Page last updated: 2024-10-20

uric acid and Diabetic Neuropathies

uric acid has been researched along with Diabetic Neuropathies in 18 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"Hyperuricemia was also significantly associated with increased risk of peripheral neuropathy in patients with type 2 diabetes (risk ratio [RR] = 2."2.53Serum Uric Acid Levels and Diabetic Peripheral Neuropathy in Type 2 Diabetes: a Systematic Review and Meta-analysis. ( Che, K; Chen, Y; Hou, X; Li, C; Wang, B; Wang, Y; Xu, D; Yan, S; Yu, S, 2016)
"Uric acid is a kind of natural antioxidant that plays a major role in the antioxidant capacity against oxidative stress."1.91Serum Uric Acid Levels Are Related to Diabetic Peripheral Neuropathy, Especially for Motor Conduction Velocity of Tibial Nerve in Type 2 Diabetes Mellitus Patients. ( Chen, Y; He, M; Vladmir, C; Wang, W; Xu, J; Zhang, H; Zhang, Y; Zhang, Z; Zhao, W; Zhou, W, 2023)
"In total, 230 patients with type 2 diabetes were examined."1.72The relation between serum uric acid levels and diabetic peripheral neuropathy in type 2 diabetes in Guilan, north of Iran. ( Assadinia, AS; Fayazi, HS; Mortazavi, SS; Sharifhassan, Z; Yaseri, M, 2022)
"299 patients with type 2 diabetes mellitus (T2DM) hospitalized in the Second Affiliated Hospital of Soochow University were enrolled."1.72Genomic DNA Methylation in Diabetic Chronic Complications in Patients With Type 2 Diabetes Mellitus. ( Hu, J; Jiang, M; Wang, X; Yang, W; Zhang, HH; Zhang, S; Zhu, Y, 2022)
"Median time to recurrence was 64 months."1.56Predictive Factors for Kidney Stone Recurrence in Type 2 Diabetes Mellitus. ( Monga, M; Prasanchaimontri, P, 2020)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's7 (38.89)24.3611
2020's6 (33.33)2.80

Authors

AuthorsStudies
Fayazi, HS1
Yaseri, M1
Mortazavi, SS1
Sharifhassan, Z1
Assadinia, AS1
Zhuang, Y1
Huang, H1
Hu, X1
Zhang, J1
Cai, Q1
Wang, X1
Yang, W1
Zhu, Y1
Zhang, S1
Jiang, M1
Hu, J1
Zhang, HH1
Takeuchi, Y1
Mizukami, H1
Kudoh, K1
Osonoi, S1
Sasaki, T1
Kushibiki, H1
Ogasawara, S1
Hara, Y1
Igawa, A1
Pan, X1
Yamada, T1
Yamazaki, K1
Mikami, T1
Daimon, M1
Yagihashi, S1
Hakamada, K1
Nakaji, S1
Zhang, H2
Vladmir, C1
Zhang, Z1
Zhou, W1
Xu, J1
Zhao, W1
Chen, Y2
He, M1
Zhang, Y1
Wang, W1
Prasanchaimontri, P1
Monga, M1
Abraham, A1
Breiner, A1
Barnett, C1
Katzberg, HD1
Lovblom, LE1
Perkins, BA1
Bril, V1
Lin, X1
Xu, L1
Zhao, D1
Luo, Z1
Pan, S1
Bell, DSH1
Yu, S1
Hou, X1
Xu, D1
Che, K1
Li, C1
Yan, S1
Wang, Y1
Wang, B1
Miric, DJ1
Kisic, BM1
Filipovic-Danic, S1
Grbic, R1
Dragojevic, I1
Miric, MB1
Puhalo-Sladoje, D1
Papanas, N2
Katsiki, N2
Papatheodorou, K2
Demetriou, M2
Papazoglou, D2
Gioka, T2
Maltezos, E2
Kotsiou, S1
Mikhailidis, DP1
Roche, S1
Moinade, S1
Newman, JH1
Elbagir, MN1
Eltom, MA1
Mahadi, EO1
Berne, C1
Hanna, AK1
Roy, M1
Zinman, B1
McCulloch, JC1
Mortimer, C1
Falk, JA1
Chipman, M1
Gordon, AS1
Marliss, EB1
Berenyi, MR1
Straus, B1
Miglietta, OE1

Reviews

1 review available for uric acid and Diabetic Neuropathies

ArticleYear
Serum Uric Acid Levels and Diabetic Peripheral Neuropathy in Type 2 Diabetes: a Systematic Review and Meta-analysis.
    Molecular neurobiology, 2016, Volume: 53, Issue:2

    Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Hyperuricemia; Publication Bias; Risk Fact

2016

Trials

1 trial available for uric acid and Diabetic Neuropathies

ArticleYear
Treatment of diabetic neuropathy with clofibrate.
    Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:9

    Topics: Adolescent; Aged; Cholesterol; Clinical Trials as Topic; Clofibrate; Diabetic Angiopathies; Diabetic

1971

Other Studies

16 other studies available for uric acid and Diabetic Neuropathies

ArticleYear
The relation between serum uric acid levels and diabetic peripheral neuropathy in type 2 diabetes in Guilan, north of Iran.
    BMC endocrine disorders, 2022, Feb-12, Volume: 22, Issue:1

    Topics: Adult; Aged; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Fem

2022
Serum uric acid and diabetic peripheral neuropathy: a double-edged sword.
    Acta neurologica Belgica, 2023, Volume: 123, Issue:3

    Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Hyperuricemia; Risk Factors; Uric Acid

2023
Genomic DNA Methylation in Diabetic Chronic Complications in Patients With Type 2 Diabetes Mellitus.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Carotid Intima-Media Thickness; Cholesterol, LDL; Creatinine; Diabetes Mellitus, Type 2; Diabetic Ne

2022
The diversity and abundance of gut microbiota are associated with the pain sensation threshold in the Japanese population.
    Neurobiology of disease, 2022, 10-15, Volume: 173

    Topics: Bacteroides; Blood Glucose; Diabetic Neuropathies; Gastrointestinal Microbiome; Glycated Hemoglobin;

2022
Serum Uric Acid Levels Are Related to Diabetic Peripheral Neuropathy, Especially for Motor Conduction Velocity of Tibial Nerve in Type 2 Diabetes Mellitus Patients.
    Journal of diabetes research, 2023, Volume: 2023

    Topics: Antioxidants; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glycated Hemoglobin; Humans; Neural

2023
Predictive Factors for Kidney Stone Recurrence in Type 2 Diabetes Mellitus.
    Urology, 2020, Volume: 143

    Topics: Aged; Asymptomatic Diseases; Body Mass Index; Calcium Oxalate; Causality; Cohort Studies; Comorbidit

2020
Uric acid levels correlate with the severity of diabetic sensorimotor polyneuropathy.
    Journal of the neurological sciences, 2017, Aug-15, Volume: 379

    Topics: Aged; Biomarkers; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus; Diabetic Neuropathies;

2017
Correlation between serum uric acid and diabetic peripheral neuropathy in T2DM patients.
    Journal of the neurological sciences, 2018, 02-15, Volume: 385

    Topics: Adult; Aged; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Humans; Male; Mi

2018
Correlation between serum uric acid and diabetic peripheral neuropathy - association rather than causation.
    Journal of the neurological sciences, 2018, 07-15, Volume: 390

    Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Uric Acid

2018
Xanthine Oxidase Activity in Type 2 Diabetes Mellitus Patients with and without Diabetic Peripheral Neuropathy.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Aged; Biomarkers; Body Mass Index; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Neuropa

2016
Peripheral neuropathy is associated with increased serum levels of uric acid in type 2 diabetes mellitus.
    Angiology, 2011, Volume: 62, Issue:4

    Topics: Adult; Aged; C-Reactive Protein; Chi-Square Distribution; Diabetes Mellitus, Type 2; Diabetic Neurop

2011
Increased serum levels of uric acid are associated with sudomotor dysfunction in subjects with type 2 diabetes mellitus.
    Experimental diabetes research, 2011, Volume: 2011

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Periphera

2011
[Study of the course of development in 84 non-insulin-dependent diabetics over a 5-to-10-year period. Their therapeutic outcome].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1983, Dec-01, Volume: 59, Issue:44

    Topics: Adult; Aged; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic

1983
The differential diagnosis of septic arthritis in the elderly.
    Comprehensive therapy, 1984, Volume: 10, Issue:8

    Topics: Aged; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Cellulitis; Diabetic Neuropathies; Di

1984
Pattern of long-term complications in Sudanese insulin-treated diabetic patients.
    Diabetes research and clinical practice, 1995, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disord

1995
An evaluation of factors associated with proliferative diabetic retinopathy.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1985, Volume: 8, Issue:2

    Topics: Adult; Angina Pectoris; Blood Coagulation; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neurop

1985