uric acid has been researched along with Diabetes Mellitus, Gestational in 24 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous evidence suggests that higher blood uric acid (UA) levels are associated with adverse cardiovascular outcomes during pregnancy and subsequent birth outcomes." | 8.31 | Associations of early pregnancy serum uric acid levels with risk of gestational diabetes and birth outcomes: a retrospective cohort study. ( Chen, GD; Guo, XL; Li, PS; Liu, ZP; Ma, HT; Pang, TT; Shen, XY; Wan, YC; Zhou, ZX, 2023) |
| "Uric acid levels during pregnancy have been examined as a potential indicator of risk for gestational diabetes mellites, hypertension, and related adverse birth outcomes." | 8.12 | Characterizing and Evaluating Diurnal Salivary Uric Acid Across Pregnancy Among Healthy Women. ( Campbell, T; Cook, SH; Giesbrecht, GF; Granger, DA; Letourneau, N; Riis, JL, 2022) |
| "To evaluate the impact of changes in uric acid over 2 years on changes in insulin sensitivity, beta-cell function, and glycemia in women with and without recent gestational diabetes (GDM), a model of the early natural history of T2DM." | 7.96 | Changes Over Time in Uric Acid in Relation to Changes in Insulin Sensitivity, Beta-Cell Function, and Glycemia. ( Connelly, PW; Hanley, AJ; Retnakaran, R; Volpe, A; Ye, C; Zinman, B, 2020) |
| " The aim of this study was to evaluate the influence of clinical and anthropometric parameters on UA and xanthine (X) levels during pregnancy and postpartum in women with physiological pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM), and to evaluate their impact on adverse perinatal outcomes." | 7.88 | Uric Acid and Xanthine Levels in Pregnancy Complicated by Gestational Diabetes Mellitus-The Effect on Adverse Pregnancy Outcomes. ( Bartakova, V; Chalasova, K; Kankova, K; Pacal, L; Pleskacova, A; Tomandl, J, 2018) |
| "To examine the association between uric acid (UA) level during the first 20 weeks of pregnancy and the development of gestational diabetes mellitus (GDM) and preeclampsia in the second half of pregnancy." | 7.78 | High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia. ( Paran, E; Sergienko, R; Sheiner, E; Wiznitzer, A; Wolak, T, 2012) |
| "The objective of this study was to evaluate the predictive values of lipids and uric acid in mid-second trimester for adverse pregnancy outcome." | 7.78 | Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes. ( Hu, Y; Wang, Z; Zhao, X; Zhou, J, 2012) |
| "Although the association between uric acid levels and adverse pregnancy outcomes has been investigated, the effects of higher uric acid levels on the risk of gestational diabetes mellitus (GDM) have yet to be established." | 5.41 | Maternal uric acid levels and risk of gestational diabetes mellitus: A systematic review and dose-response meta-analysis of cohort studies including 105,380 participants. ( Bagheri, R; Ghanavati, M; Mohammadpour, S; Nikparast, A; Rahmani, J; Shadnoosh, M; Wong, A, 2023) |
| " The exposure factor was serum uric acid before 24 weeks of gestation, primary outcome was gestational diabetes diagnosed at 24 to 28 weeks of gestation, and secondary outcomes were GDM A2 (GDM requiring pharmacotherapy), GDM combined with pre-eclampsia, preterm delivery, and large for gestational age infants." | 4.31 | Elevated Serum Uric Acid Is Associated With Gestational Diabetes Mellitus: An Observational Cohort Study. ( Li, X; Ying, C; Yue, C, 2023) |
| "Previous evidence suggests that higher blood uric acid (UA) levels are associated with adverse cardiovascular outcomes during pregnancy and subsequent birth outcomes." | 4.31 | Associations of early pregnancy serum uric acid levels with risk of gestational diabetes and birth outcomes: a retrospective cohort study. ( Chen, GD; Guo, XL; Li, PS; Liu, ZP; Ma, HT; Pang, TT; Shen, XY; Wan, YC; Zhou, ZX, 2023) |
| "Uric acid levels during pregnancy have been examined as a potential indicator of risk for gestational diabetes mellites, hypertension, and related adverse birth outcomes." | 4.12 | Characterizing and Evaluating Diurnal Salivary Uric Acid Across Pregnancy Among Healthy Women. ( Campbell, T; Cook, SH; Giesbrecht, GF; Granger, DA; Letourneau, N; Riis, JL, 2022) |
| "To evaluate the impact of changes in uric acid over 2 years on changes in insulin sensitivity, beta-cell function, and glycemia in women with and without recent gestational diabetes (GDM), a model of the early natural history of T2DM." | 3.96 | Changes Over Time in Uric Acid in Relation to Changes in Insulin Sensitivity, Beta-Cell Function, and Glycemia. ( Connelly, PW; Hanley, AJ; Retnakaran, R; Volpe, A; Ye, C; Zinman, B, 2020) |
| " Aimed of this study was to evaluate the serum creatinine and uric acid levels in Bangladeshi women with GDM in their second and third trimester of pregnancy." | 3.91 | Estimation of Serum Creatinine and Uric Acid in Bangladeshi Gestational Diabetic Mother Attending in Tertiary Care Hospital. ( Baral, N; Ferdous, N; Khan, NZ; Mishu, FA; Nahar, S; Sultana, GS; Yesmin, MS, 2019) |
| " The aim of this study was to evaluate the influence of clinical and anthropometric parameters on UA and xanthine (X) levels during pregnancy and postpartum in women with physiological pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM), and to evaluate their impact on adverse perinatal outcomes." | 3.88 | Uric Acid and Xanthine Levels in Pregnancy Complicated by Gestational Diabetes Mellitus-The Effect on Adverse Pregnancy Outcomes. ( Bartakova, V; Chalasova, K; Kankova, K; Pacal, L; Pleskacova, A; Tomandl, J, 2018) |
| " Serum glucose, lipids, uric acid, insulin and vaspin were measured at the 2nd and 3rd trimester of pregnancy and postpartum." | 3.79 | Serum vaspin levels in women with and without gestational diabetes mellitus during pregnancy and postpartum. ( Anastasilakis, AD; Dagklis, T; Gavana, E; Gerou, S; Giannoulis, C; Gkiomisi, A; Kourtis, A; Makedou, KG; Polyzos, SA; Rousso, D, 2013) |
| "To examine the association between uric acid (UA) level during the first 20 weeks of pregnancy and the development of gestational diabetes mellitus (GDM) and preeclampsia in the second half of pregnancy." | 3.78 | High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia. ( Paran, E; Sergienko, R; Sheiner, E; Wiznitzer, A; Wolak, T, 2012) |
| "The objective of this study was to evaluate the predictive values of lipids and uric acid in mid-second trimester for adverse pregnancy outcome." | 3.78 | Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes. ( Hu, Y; Wang, Z; Zhao, X; Zhou, J, 2012) |
| "During normal pregnancy, plasma concentrations of creatinine and uric acid normally decrease as a consequence of their increased glomerular filtration." | 3.73 | Relationship between serum uric acid, creatinine, albumin and gestational diabetes mellitus. ( Danişman, N; Güngör, ES; Mollamahmutoğlu, L, 2006) |
| "Uric acid has strong antioxidant activity, whereas its oxidative damage is closely related to many diseases." | 1.62 | The protective role of serum uric acid against premature membrane rupture in gestational diabetes: a cross-sectional study. ( Guo, M; Hou, W; Hu, X; Lu, J; Pang, S; Yu, X, 2021) |
| "Uric acid was measured in 1570 plasma samples collected at mean gestational age of 8." | 1.35 | Elevated first-trimester uric acid concentrations are associated with the development of gestational diabetes. ( Catov, J; Gandley, RE; Laughon, SK; Provins, T; Roberts, JM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 10 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 2 |
| Fan, K | 1 |
| Jin, L | 1 |
| Riis, JL | 1 |
| Cook, SH | 1 |
| Letourneau, N | 1 |
| Campbell, T | 1 |
| Granger, DA | 1 |
| Giesbrecht, GF | 1 |
| Hu, T | 1 |
| An, Z | 1 |
| Li, H | 1 |
| Liu, Y | 1 |
| Xia, L | 1 |
| Qiu, L | 1 |
| Yao, A | 1 |
| Ma, L | 1 |
| Liu, L | 1 |
| Yue, C | 1 |
| Ying, C | 1 |
| Li, X | 2 |
| Nikparast, A | 1 |
| Rahmani, J | 1 |
| Bagheri, R | 1 |
| Mohammadpour, S | 1 |
| Shadnoosh, M | 1 |
| Wong, A | 1 |
| Ghanavati, M | 1 |
| Su, S | 1 |
| Zhang, E | 1 |
| Gao, S | 1 |
| Zhang, Y | 1 |
| Liu, J | 1 |
| Xie, S | 1 |
| Yue, W | 1 |
| Liu, R | 1 |
| Yin, C | 1 |
| Pang, TT | 1 |
| Zhou, ZX | 1 |
| Li, PS | 1 |
| Ma, HT | 1 |
| Shen, XY | 1 |
| Wan, YC | 1 |
| Guo, XL | 1 |
| Liu, ZP | 1 |
| Chen, GD | 1 |
| Volpe, A | 1 |
| Ye, C | 1 |
| Hanley, AJ | 1 |
| Connelly, PW | 1 |
| Zinman, B | 1 |
| Retnakaran, R | 1 |
| Ye, Y | 1 |
| Xiong, Y | 1 |
| Zhou, Q | 1 |
| Wu, J | 1 |
| Xiao, X | 1 |
| Guo, M | 1 |
| Lu, J | 1 |
| Yu, X | 1 |
| Hu, X | 1 |
| Hou, W | 1 |
| Pang, S | 1 |
| Leng, J | 1 |
| Wang, L | 1 |
| Wang, J | 1 |
| Li, W | 1 |
| Liu, H | 1 |
| Zhang, S | 1 |
| Li, L | 1 |
| Tian, H | 1 |
| Xun, P | 1 |
| Yang, X | 1 |
| Yu, Z | 1 |
| Hu, G | 1 |
| Pleskacova, A | 1 |
| Bartakova, V | 1 |
| Chalasova, K | 1 |
| Pacal, L | 1 |
| Kankova, K | 1 |
| Tomandl, J | 1 |
| Mishu, FA | 1 |
| Baral, N | 1 |
| Ferdous, N | 1 |
| Nahar, S | 1 |
| Khan, NZ | 1 |
| Sultana, GS | 1 |
| Yesmin, MS | 1 |
| Maged, AM | 1 |
| Moety, GA | 1 |
| Mostafa, WA | 1 |
| Hamed, DA | 1 |
| Molęda, P | 1 |
| Fronczyk, A | 1 |
| Safranow, K | 1 |
| Majkowska, L | 1 |
| Cheng, D | 1 |
| Zhao, J | 1 |
| Jian, L | 1 |
| Ding, T | 1 |
| Liu, S | 1 |
| Kharb, S | 1 |
| Laughon, SK | 1 |
| Catov, J | 1 |
| Provins, T | 1 |
| Roberts, JM | 1 |
| Gandley, RE | 1 |
| Wolak, T | 1 |
| Sergienko, R | 1 |
| Wiznitzer, A | 1 |
| Paran, E | 1 |
| Sheiner, E | 1 |
| Tisi, DK | 1 |
| Burns, DH | 1 |
| Luskey, GW | 1 |
| Koski, KG | 1 |
| Zhou, J | 1 |
| Zhao, X | 1 |
| Wang, Z | 1 |
| Hu, Y | 1 |
| Gkiomisi, A | 1 |
| Makedou, KG | 1 |
| Anastasilakis, AD | 1 |
| Polyzos, SA | 1 |
| Kourtis, A | 1 |
| Gerou, S | 1 |
| Gavana, E | 1 |
| Dagklis, T | 1 |
| Rousso, D | 1 |
| Giannoulis, C | 1 |
| Seghieri, G | 1 |
| Breschi, MC | 1 |
| Anichini, R | 1 |
| De Bellis, A | 1 |
| Alviggi, L | 1 |
| Maida, I | 1 |
| Franconi, F | 1 |
| Güngör, ES | 1 |
| Danişman, N | 1 |
| Mollamahmutoğlu, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Early Screening and Intervention for Gestational Diabetes Mellitus on Pregnancy Outcomes: the TESGO Randomized Trial[NCT03523143] | 967 participants (Actual) | Interventional | 2018-06-11 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for uric acid and Diabetes Mellitus, Gestational
| Article | Year |
|---|---|
Maternal uric acid levels and risk of gestational diabetes mellitus: A systematic review and dose-response meta-analysis of cohort studies including 105,380 participants.
Topics: Cohort Studies; Diabetes, Gestational; Female; Humans; Odds Ratio; Pregnancy; Pregnancy Outcome; Uri | 2023 |
Serum uric acid and the risk of gestational diabetes mellitus: a systematic review and meta-analysis.
Topics: Diabetes, Gestational; Female; Humans; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, S | 2023 |
22 other studies available for uric acid and Diabetes Mellitus, Gestational
| Article | Year |
|---|---|
Serum uric acid in early pregnancy and risk of gestational diabetes mellitus: A cohort study of 85,609 pregnant women.
Topics: China; Cohort Studies; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Pregnancy; | 2022 |
Characterizing and Evaluating Diurnal Salivary Uric Acid Across Pregnancy Among Healthy Women.
Topics: Body Mass Index; Diabetes, Gestational; Female; Gestational Weight Gain; Humans; Pregnancy; Pregnanc | 2022 |
UHPLC-MS/MS-Based Metabolomics and Clinical Phenotypes Analysis Reveal Broad-Scale Perturbations in Early Pregnancy Related to Gestational Diabetes Mellitus.
Topics: Chromatography, High Pressure Liquid; Diabetes, Gestational; Female; Humans; Metabolomics; Phenotype | 2022 |
Elevated Serum Uric Acid Is Associated With Gestational Diabetes Mellitus: An Observational Cohort Study.
Topics: Cohort Studies; Diabetes, Gestational; Female; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pr | 2023 |
Associations of early pregnancy serum uric acid levels with risk of gestational diabetes and birth outcomes: a retrospective cohort study.
Topics: Diabetes, Gestational; Female; Fetal Growth Retardation; Fetal Macrosomia; Humans; Hyperuricemia; In | 2023 |
Changes Over Time in Uric Acid in Relation to Changes in Insulin Sensitivity, Beta-Cell Function, and Glycemia.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glucose Tolerance Te | 2020 |
Comparison of Machine Learning Methods and Conventional Logistic Regressions for Predicting Gestational Diabetes Using Routine Clinical Data: A Retrospective Cohort Study.
Topics: Adult; Blood Glucose; Cholesterol; Clinical Decision Rules; Cohort Studies; Decision Trees; Diabetes | 2020 |
The protective role of serum uric acid against premature membrane rupture in gestational diabetes: a cross-sectional study.
Topics: Adult; Cross-Sectional Studies; Diabetes, Gestational; Female; Fetal Membranes, Premature Rupture; H | 2021 |
Uric acid and diabetes risk among Chinese women with a history of gestational diabetes mellitus.
Topics: Adult; Asian People; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetes, Gestational; Fema | 2017 |
Uric Acid and Xanthine Levels in Pregnancy Complicated by Gestational Diabetes Mellitus-The Effect on Adverse Pregnancy Outcomes.
Topics: Adult; Biomarkers; Case-Control Studies; Diabetes, Gestational; Female; Humans; Pregnancy; Pregnancy | 2018 |
Estimation of Serum Creatinine and Uric Acid in Bangladeshi Gestational Diabetic Mother Attending in Tertiary Care Hospital.
Topics: Adult; Asian People; Bangladesh; Blood Glucose; Creatinine; Cross-Sectional Studies; Diabetes, Gesta | 2019 |
Comparative study between different biomarkers for early prediction of gestational diabetes mellitus.
Topics: Adult; Albumins; Biomarkers; C-Reactive Protein; Creatinine; Diabetes, Gestational; Early Diagnosis; | 2014 |
Is Uric Acid a Missing Link between Previous Gestational Diabetes Mellitus and the Development of Type 2 Diabetes at a Later Time of Life?
Topics: Adult; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Gluco | 2016 |
Relationship between red cell distribution width and early renal injury in patients with gestational diabetes mellitus.
Topics: Acute Kidney Injury; Adult; Albuminuria; Blood Urea Nitrogen; China; Creatinine; Cross-Sectional Stu | 2016 |
Total radical-trapping antioxidant potential in gestational diabetes.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Case-Control Studies; Diabetes, Gestational; Female; | 2008 |
Elevated first-trimester uric acid concentrations are associated with the development of gestational diabetes.
Topics: Body Mass Index; Diabetes, Gestational; Female; Humans; Hyperuricemia; Insulin Resistance; Logistic | 2009 |
High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia.
Topics: Adult; Biomarkers; Diabetes, Gestational; Female; Humans; Multivariate Analysis; Pre-Eclampsia; Preg | 2012 |
Fetal exposure to altered amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1 occurs before screening for gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Amniotic Fluid; Diabetes, Gestational; Female; Glucose; Humans; Insuli | 2011 |
Combination of lipids and uric acid in mid-second trimester can be used to predict adverse pregnancy outcomes.
Topics: Adult; Diabetes, Gestational; Female; Humans; Lipids; Longitudinal Studies; Pre-Eclampsia; Pregnancy | 2012 |
Serum vaspin levels in women with and without gestational diabetes mellitus during pregnancy and postpartum.
Topics: Adult; Blood Glucose; Diabetes, Gestational; Female; Glucose; Humans; Insulin; Insulin Resistance; L | 2013 |
Serum homocysteine levels are increased in women with gestational diabetes mellitus.
Topics: Adult; Blood Glucose; Blood Pressure; Case-Control Studies; Diabetes, Gestational; Female; Folic Aci | 2003 |
Relationship between serum uric acid, creatinine, albumin and gestational diabetes mellitus.
Topics: Adult; Creatinine; Diabetes, Gestational; Female; Glomerular Filtration Rate; Glucose Tolerance Test | 2006 |