Page last updated: 2024-10-20

uric acid and Depression, Involutional

uric acid has been researched along with Depression, Involutional in 20 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
"We aimed to investigate the difference in serum uric acid(SUA)levels between subtypes of depression and normal population, and whether SUA can be used to identify bipolar disorder depressive episode and major depressive disorder and predict the length of hospital stay."7.96Serum uric acid a depression biomarker. ( Deng, W; Huang, X; Li, J; Li, T; Meng, X, 2020)
"Uric acid (UA) has been suggested as a possible biomarker of bipolar disorder (BD) in recent studies."7.96Comparison of Serum Uric Acid in Major Depressive Disorder and Bipolar Disorder: a Retrospective Chart Review Study. ( Ahn, YM; Kim, S; Rhee, SJ; Song, Y, 2020)
"This large scale study finds plasma uric acid levels are lower in current, but not remitted, MDD and/or anxiety disorders, according to a dose-response gradient."7.88Uric acid in major depressive and anxiety disorders. ( Black, CN; Bot, M; Penninx, BWJH; Scheffer, PG; Snieder, H, 2018)
"We aimed to investigate the difference in serum uric acid(SUA)levels between subtypes of depression and normal population, and whether SUA can be used to identify bipolar disorder depressive episode and major depressive disorder and predict the length of hospital stay."3.96Serum uric acid a depression biomarker. ( Deng, W; Huang, X; Li, J; Li, T; Meng, X, 2020)
"Uric acid (UA) has been suggested as a possible biomarker of bipolar disorder (BD) in recent studies."3.96Comparison of Serum Uric Acid in Major Depressive Disorder and Bipolar Disorder: a Retrospective Chart Review Study. ( Ahn, YM; Kim, S; Rhee, SJ; Song, Y, 2020)
"This large scale study finds plasma uric acid levels are lower in current, but not remitted, MDD and/or anxiety disorders, according to a dose-response gradient."3.88Uric acid in major depressive and anxiety disorders. ( Black, CN; Bot, M; Penninx, BWJH; Scheffer, PG; Snieder, H, 2018)
"This study aimed to a) examine IR and β-cell function as measured by the homeostasis model assessment of insulin resistance (HOMA-IR) and insulin sensitivity and β cell function (HOMA-B) and glucotoxicity (conceptualized as increased glucose levels versus lowered HOMA-B values) in 74 participants with major depressive disorder (MDD) and bipolar disorder, with and or without MetS and TUD, versus 46 healthy controls, and b) whether IR is associated with IO&NS biomarkers, including nitric oxide metabolites (NOx), lipid hydroperoxides (LOOH), plasma advanced oxidation protein products (AOPP), C-reactive protein (CRP), haptoglobin (Hp) and uric acid."3.85Indices of insulin resistance and glucotoxicity are not associated with bipolar disorder or major depressive disorder, but are differently associated with inflammatory, oxidative and nitrosative biomarkers. ( Berk, M; Camargo, AEI; de Farias, CC; Dodd, S; Favaro Soares, J; Gastaldello Moreira, E; Higachi, L; Landucci Bonifácio, K; Maes, M; Nunes, SOV; Odebrecht Vargas, H; Sabbatini Barbosa, D, 2017)
"Findings of this study add evidence to the role of uric acid as state, rather than trait, marker in bipolar disorders."3.85Purinergic system dysfunctions in subjects with bipolar disorder: A comparative cross-sectional study. ( Bartoli, F; Brosio, E; Capuzzi, E; Carrà, G; Clerici, M; Crocamo, C; Dakanalis, A; Miotto, A, 2017)
"Individuals with major depressive disorder (MDD) have a high suicide risk."1.56Association of serum uric acid levels with suicide risk in female patients with major depressive disorder: a comparative cross-sectional study. ( Chen, JX; Feng, JH; Liu, Y; Su, YA; Tan, YL; Wang, SL; Yang, FD; Zhang, LG, 2020)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's10 (50.00)24.3611
2020's8 (40.00)2.80

Authors

AuthorsStudies
Lu, Z1
Wang, Y2
Xun, G1
Ceresa, A1
Esposito, CM1
Surace, T1
Legnani, F1
Cirella, L1
Cetti, D1
Di Paolo, M1
Nosari, G1
Zanelli Quarantini, F1
Serati, M1
Ciappolino, V1
Caldiroli, A1
Capuzzi, E2
Buoli, M1
Zhu, Y1
Wu, X1
Liu, H1
Niu, Z1
Zhao, J1
Wang, F1
Mao, R1
Guo, X1
Zhang, C1
Wang, Z1
Chen, J1
Fang, Y1
Chen, Z1
Liang, S1
Bai, Y1
Lin, J1
Li, M1
Mo, Z1
Xie, S1
Huang, S1
Long, J1
Meng, X1
Huang, X1
Deng, W1
Li, J1
Li, T1
Kim, S1
Rhee, SJ1
Song, Y1
Ahn, YM1
Chen, JX1
Feng, JH1
Zhang, LG1
Liu, Y1
Yang, FD1
Wang, SL1
Tan, YL1
Su, YA1
Zhao, SS1
Qian, Y1
Mackie, SL1
Wen, C1
Mao, Y1
Landucci Bonifácio, K1
Sabbatini Barbosa, D1
Gastaldello Moreira, E1
de Farias, CC1
Higachi, L1
Camargo, AEI1
Favaro Soares, J1
Odebrecht Vargas, H1
Nunes, SOV2
Berk, M1
Dodd, S1
Maes, M2
Black, CN1
Bot, M1
Scheffer, PG1
Snieder, H1
Penninx, BWJH1
Bonifacio, KL1
Morelli, NR1
Vargas, HO1
Moreira, EG1
St Stoyanov, D1
Barbosa, DS1
Carvalho, AF1
Dos Santos Oliveira, PM1
Santos, V1
Coroa, M1
Ribeiro, J1
Madeira, N1
Bartoli, F2
Crocamo, C2
Carrà, G2
Wiener, C1
Rassier, GT1
Kaster, MP1
Jansen, K1
Pinheiro, RT1
Klamt, F1
Magalhães, PV1
Kapczinski, F1
Ghisleni, G1
da Silva, RA1
Lyngdoh, T1
Bochud, M1
Glaus, J1
Castelao, E1
Waeber, G1
Vollenweider, P1
Preisig, M1
Zheng, P1
Chen, JJ1
Huang, T1
Wang, MJ1
Dong, MX1
Huang, YJ1
Zhou, LK1
Xie, P1
Jiménez-Fernández, S1
Gurpegui, M1
Díaz-Atienza, F1
Pérez-Costillas, L1
Gerstenberg, M1
Correll, CU1
Dakanalis, A1
Brosio, E1
Miotto, A1
Clerici, M1
Grimaldi, S1
Englund, A1
Partonen, T1
Haukka, J1
Pirkola, S1
Reunanen, A1
Aromaa, A1
Lönnqvist, J1
Sarandol, A1
Sarandol, E1
Eker, SS1
Erdinc, S1
Vatansever, E1
Kirli, S1

Reviews

2 reviews available for uric acid and Depression, Involutional

ArticleYear
Serum uric acid is not associated with major depressive disorder in European and South American populations: a meta-analysis and two-sample bidirectional Mendelian Randomization study.
    European journal of clinical nutrition, 2022, Volume: 76, Issue:12

    Topics: Causality; Depressive Disorder, Major; Humans; Mendelian Randomization Analysis; Polymorphism, Singl

2022
Oxidative stress and antioxidant parameters in patients with major depressive disorder compared to healthy controls before and after antidepressant treatment: results from a meta-analysis.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:12

    Topics: Antidepressive Agents; Depressive Disorder, Major; Humans; Nitrites; Oxidative Stress; Peroxidases;

2015

Other Studies

18 other studies available for uric acid and Depression, Involutional

ArticleYear
Individuals with bipolar disorder have a higher level of uric acid than major depressive disorder: a case-control study.
    Scientific reports, 2021, 09-15, Volume: 11, Issue:1

    Topics: Adult; Antidepressive Agents; Biomarkers; Bipolar Disorder; Case-Control Studies; Depressive Disorde

2021
Gender differences in clinical and biochemical parameters of patients consecutively hospitalized for unipolar depression.
    Psychiatry research, 2022, Volume: 310

    Topics: Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Female; Humans; Male; Sex Factors; U

2022
Employing biochemical biomarkers for building decision tree models to predict bipolar disorder from major depressive disorder.
    Journal of affective disorders, 2022, 07-01, Volume: 308

    Topics: Bilirubin; Biomarkers; Bipolar Disorder; Decision Trees; Depressive Disorder, Major; Female; Humans;

2022
Serum uric acid a depression biomarker.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Biomarkers; Bipolar Disorder; Case-Control Studies; China; Depression; Depr

2020
Comparison of Serum Uric Acid in Major Depressive Disorder and Bipolar Disorder: a Retrospective Chart Review Study.
    Journal of Korean medical science, 2020, Jul-20, Volume: 35, Issue:28

    Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Biomarkers; Bipolar Disorder;

2020
Association of serum uric acid levels with suicide risk in female patients with major depressive disorder: a comparative cross-sectional study.
    BMC psychiatry, 2020, 09-29, Volume: 20, Issue:1

    Topics: Cross-Sectional Studies; Depressive Disorder, Major; Female; Humans; Psychiatric Status Rating Scale

2020
Genetically predicted serum urate levels have no causal role on depression or other psychiatric disorders.
    Clinical rheumatology, 2021, Volume: 40, Issue:9

    Topics: Anxiety; Causality; Depression; Depressive Disorder, Major; Genome-Wide Association Study; Gout; Hum

2021
Indices of insulin resistance and glucotoxicity are not associated with bipolar disorder or major depressive disorder, but are differently associated with inflammatory, oxidative and nitrosative biomarkers.
    Journal of affective disorders, 2017, Volume: 222

    Topics: Adult; Biomarkers; Bipolar Disorder; Blood Glucose; Body Mass Index; C-Reactive Protein; Cross-Secti

2017
Uric acid in major depressive and anxiety disorders.
    Journal of affective disorders, 2018, 01-01, Volume: 225

    Topics: Adult; Antidepressive Agents; Anxiety Disorders; Cross-Sectional Studies; Depressive Disorder, Major

2018
Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Adult; Advanced Oxidation Protein Products; Analysis of Variance; Anxiety Disorders; Aryldialkylphos

2018
Serum uric acid as a predictor of bipolarity in individuals with a major depressive episode.
    Bipolar disorders, 2019, Volume: 21, Issue:3

    Topics: Adult; Biomarkers; Bipolar Disorder; Cyclothymic Disorder; Depressive Disorder, Major; Female; Human

2019
Differences in serum uric acid between 'unipolar' and 'bipolar' depression: Preliminary data.
    Bipolar disorders, 2019, Volume: 21, Issue:3

    Topics: Bipolar Disorder; Depression; Depressive Disorder, Major; Humans; Preliminary Data; Uric Acid

2019
Gender-based differences in oxidative stress parameters do not underlie the differences in mood disorders susceptibility between sexes.
    European psychiatry : the journal of the Association of European Psychiatrists, 2014, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Advanced Oxidation Protein Products; Bipolar Disorder; Brazil; Case-Control Studi

2014
Associations of serum uric acid and SLC2A9 variant with depressive and anxiety disorders: a population-based study.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Anxiety Disorders; Comorbidity; Cross-Sectional Studies; Depressive Disorder, Major; Female;

2013
A novel urinary metabolite signature for diagnosing major depressive disorder.
    Journal of proteome research, 2013, Dec-06, Volume: 12, Issue:12

    Topics: Adult; Biomarkers; Case-Control Studies; Depressive Disorder, Major; Dicarboxylic Acids; Discriminan

2013
Purinergic system dysfunctions in subjects with bipolar disorder: A comparative cross-sectional study.
    Comprehensive psychiatry, 2017, Volume: 73

    Topics: Adolescent; Adult; Aged; Bilirubin; Biomarkers; Bipolar Disorder; Case-Control Studies; Creatinine;

2017
Experienced poor lighting contributes to the seasonal fluctuations in weight and appetite that relate to the metabolic syndrome.
    Journal of environmental and public health, 2009, Volume: 2009

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Alcohol-Related Disorders; Anxiety Disorders; Appe

2009
Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems.
    Human psychopharmacology, 2007, Volume: 22, Issue:2

    Topics: Adult; Antidepressive Agents; Antioxidants; Ascorbic Acid; Carotenoids; Depressive Disorder, Major;

2007