Page last updated: 2024-10-20

uric acid and Dementia, Vascular

uric acid has been researched along with Dementia, Vascular in 13 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)

Research Excerpts

ExcerptRelevanceReference
"To explore the association between uric acid (UA) levels and vascular dementia (VaD) and Parkinson's disease dementia (PDD), a meta-analysis was conducted."9.41Uric acid levels and their association with vascular dementia and Parkinson's disease dementia: a meta-analysis. ( Cen, K; Cui, Y; Feng, X; Hou, X; Li, Q, 2023)
"To explore the association between uric acid (UA) levels and vascular dementia (VaD) and Parkinson's disease dementia (PDD), a meta-analysis was conducted."5.41Uric acid levels and their association with vascular dementia and Parkinson's disease dementia: a meta-analysis. ( Cen, K; Cui, Y; Feng, X; Hou, X; Li, Q, 2023)
" The single ascending dose of Naoqingzhiming tablet (180-2160 mg) were well tolerated in all enrolled subjects, without serious adverse events and adverse events leading to withdrawal from the study."3.11Safety, tolerability and pharmacokinetics of a Class I natural medicine with therapeutic potential for vascular dementia: Naoqingzhiming tablet. ( Cao, Y; Chen, M; Han, Y; Jiang, H; Jiang, X; Li, T; Lin, P; Liu, X; Sun, F; Tao, Y; Yan, F, 2022)
"It is known that hyperuricemia is recognized as an independent cardiovascular risk factor."2.82[The role of hyperuricemia in the development of cognitive changes in the elderly.] ( Ariev, AL; Kunitskaya, NA, 2022)
"Hyperuricemia has been recognized as an independent cardiovascular risk factor in epidemiological studies."2.58Uric Acid and Cognitive Function in Older Individuals. ( Meschi, T; Nouvenne, A; Prati, B; Tana, C; Ticinesi, A, 2018)
"Uric acid (UA) is an endogenous antioxidant, low levels of which are also implicated in neurodegenerative disease."1.91The Influence of Agricultural Work and Plasma Uric Acid on Hospital Admission for Alzheimer's Disease. ( Liu, H; Reynolds, GP; Wei, X, 2023)
"Uric acid (UA) is a major contributor to naturally-occurring antioxidant activity and is thought to have protective effects against neurodegenerative processes."1.56Uric Acid and High-Density Lipoprotein Cholesterol Are Differently Associated with Alzheimer's Disease and Vascular Dementia. ( Liu, H; Reynolds, GP; Wei, X, 2020)
"Uric acid (UA) has long been implicated as a critical cause of cardiovascular disease."1.46Uric acid is associated with vascular dementia in Chinese population. ( Cui, R; Liu, Y; Lu, K; Wang, Q; Xu, Y; Zhao, Y, 2017)
"the bilirubin level was obviously lower while the ua level was significantly higher in the Sivd group when compared with the controls."1.40Serum antioxidant levels associated with subcortical ischemic vascular disease. ( Hao, J; Liu, H; Sun, Z; Wang, L; Zhang, C; Zhou, X; Zhu, M; Zhu, X, 2014)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's5 (38.46)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Lin, P1
Tao, Y1
Sun, F1
Jiang, X1
Li, T1
Liu, X1
Chen, M1
Jiang, H1
Yan, F1
Han, Y1
Cao, Y1
Kunitskaya, NA1
Ariev, AL1
Li, Q1
Cen, K1
Cui, Y1
Feng, X1
Hou, X1
Liu, H3
Reynolds, GP2
Wei, X2
Serdarevic, N1
Stanciu, AE1
Begic, L1
Uncanin, S1
Tana, C1
Ticinesi, A1
Prati, B1
Nouvenne, A1
Meschi, T1
Scheepers, LEJM1
Jacobsson, LTH1
Kern, S1
Johansson, L1
Dehlin, M1
Skoog, I1
Cervellati, C1
Romani, A1
Seripa, D1
Cremonini, E1
Bosi, C1
Magon, S1
Passaro, A1
Bergamini, CM1
Pilotto, A1
Zuliani, G1
Zhou, X1
Wang, L1
Zhang, C1
Zhu, M1
Zhu, X1
Hao, J1
Sun, Z1
Xu, Y1
Wang, Q1
Cui, R1
Lu, K1
Liu, Y1
Zhao, Y1
Gackowski, D1
Rozalski, R1
Siomek, A1
Dziaman, T1
Nicpon, K1
Klimarczyk, M1
Araszkiewicz, A1
Olinski, R1
Tohgi, H1
Abe, T1
Takahashi, S1
Kikuchi, T1

Reviews

3 reviews available for uric acid and Dementia, Vascular

ArticleYear
[The role of hyperuricemia in the development of cognitive changes in the elderly.]
    Advances in gerontology = Uspekhi gerontologii, 2022, Volume: 35, Issue:5

    Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Dementia; Dementia, Vascular; Humans; Hyp

2022
Uric acid levels and their association with vascular dementia and Parkinson's disease dementia: a meta-analysis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023, Volume: 44, Issue:6

    Topics: Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Parkinson Disease; Reproducibility of Resul

2023
Uric Acid and Cognitive Function in Older Individuals.
    Nutrients, 2018, Jul-27, Volume: 10, Issue:8

    Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Dementia; Dementia, Vascular; Disease Pro

2018

Trials

1 trial available for uric acid and Dementia, Vascular

ArticleYear
Safety, tolerability and pharmacokinetics of a Class I natural medicine with therapeutic potential for vascular dementia: Naoqingzhiming tablet.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Area Under Curve; Dementia, Vascular; Dose-Response Relationship, Drug; Double-Blind Method; Healthy

2022

Other Studies

9 other studies available for uric acid and Dementia, Vascular

ArticleYear
The Influence of Agricultural Work and Plasma Uric Acid on Hospital Admission for Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 92, Issue:4

    Topics: Alzheimer Disease; Dementia, Vascular; Hospitals; Humans; Neurodegenerative Diseases; Pesticides; Ur

2023
Uric Acid and High-Density Lipoprotein Cholesterol Are Differently Associated with Alzheimer's Disease and Vascular Dementia.
    Journal of Alzheimer's disease : JAD, 2020, Volume: 73, Issue:3

    Topics: Aged; Alzheimer Disease; Biomarkers; Brain; Cholesterol, HDL; Dementia, Vascular; Female; Humans; Ma

2020
Serum Uric Acid Concentration in Patients with Cerebrovascular Disease (Ischemic Stroke and Vascular Dementia).
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2020, Volume: 74, Issue:2

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cerebrovascular Disorders; Dementia, Vascular; Humans

2020
Urate and risk of Alzheimer's disease and vascular dementia: A population-based study.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2019, Volume: 15, Issue:6

    Topics: Adult; Alzheimer Disease; Dementia, Vascular; Female; Humans; Longitudinal Studies; Middle Aged; Ris

2019
Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.
    Journal of the neurological sciences, 2014, Feb-15, Volume: 337, Issue:1-2

    Topics: Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cogni

2014
Serum antioxidant levels associated with subcortical ischemic vascular disease.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Aged; Antioxidants; Bilirubin; Biomarkers; Brain Ischemia; Cross-Sectional Studies; Dementia, Vascul

2014
Uric acid is associated with vascular dementia in Chinese population.
    Brain and behavior, 2017, Volume: 7, Issue:2

    Topics: Aged; China; Cognitive Dysfunction; Dementia, Vascular; Female; Humans; Male; Middle Aged; Protectiv

2017
Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia.
    Journal of the neurological sciences, 2008, Mar-15, Volume: 266, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Ascorbic Acid

2008
The urate and xanthine concentrations in the cerebrospinal fluid in patients with vascular dementia of the Binswanger type, Alzheimer type dementia, and Parkinson's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:2

    Topics: Aged; Alzheimer Disease; Dementia, Multi-Infarct; Dementia, Vascular; Humans; Parkinson Disease; Psy

1993