Page last updated: 2024-10-20

uric acid and Deficiency, Vitamin D

uric acid has been researched along with Deficiency, Vitamin D in 21 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the relationship of vitamin D status and vitamin D replacement therapy with glycemic control, serum uric acid (SUA) levels, and microalbuminuria (MAU) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD)."7.85The Association of Vitamin D Status and Vitamin D Replacement Therapy with Glycemic Control, Serum Uric Acid Levels, and Microalbuminuria in Patients with Type 2 Diabetes and Chronic Kidney Disease. ( Acikgoz, SB; Genc, AB; Sipahi, S; Solak, Y; Tamer, A; Yildirim, M, 2017)
"Elevated serum uric acid (SUA) level is strongly associated with prevalence of metabolic syndrome (MS), elevated parathyroid hormone (PTH) levels, and 25-hydroxyvitamin D [25(OH)D] insufficiency in adults."7.83Uric Acid-Induced Inflammation Is Mediated by the Parathyroid Hormone:25-Hydroxyvitamin D Ratio in Obese Adolescents. ( Alemzadeh, R; Kichler, J, 2016)
" A short-term administration of allopurinol increases plasma concentrations of 1,25(OH)2D3 in mild to moderate renal failure, with or without hyperuricemia."5.19Inhibition of xanthine oxidase and exercise on serum uric acid, 25(OH)D3, and calcium concentrations. ( Lippi, G; Salvagno, GL; Sanchis-Gomar, F, 2014)
" Compared to nonadenomatous polyps, older age, higher 25(OH) vitamin D and higher uric acid levels were at increased risk for adenomatous polyps."4.31Association of 25(OH)-Vitamin D and metabolic factors with colorectal polyps. ( Chang, YJ; Chao, JN; Chiang, CH; He, SR; Liu, YT; Yang, CH, 2023)
"To evaluate the relationship of vitamin D status and vitamin D replacement therapy with glycemic control, serum uric acid (SUA) levels, and microalbuminuria (MAU) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD)."3.85The Association of Vitamin D Status and Vitamin D Replacement Therapy with Glycemic Control, Serum Uric Acid Levels, and Microalbuminuria in Patients with Type 2 Diabetes and Chronic Kidney Disease. ( Acikgoz, SB; Genc, AB; Sipahi, S; Solak, Y; Tamer, A; Yildirim, M, 2017)
"Elevated serum uric acid (SUA) level is strongly associated with prevalence of metabolic syndrome (MS), elevated parathyroid hormone (PTH) levels, and 25-hydroxyvitamin D [25(OH)D] insufficiency in adults."3.83Uric Acid-Induced Inflammation Is Mediated by the Parathyroid Hormone:25-Hydroxyvitamin D Ratio in Obese Adolescents. ( Alemzadeh, R; Kichler, J, 2016)
" Safety was monitored based on adverse events recorded during the treatment period and on the results of laboratory tests, including measurement of creatinine and uric acid levels."2.71Clinical and laboratory safety of one year's use of a combination calcium + vitamin D tablet in ambulatory elderly women with vitamin D insufficiency: results of a multicenter, randomized, double-blind, placebo-controlled study. ( Brazier, M; Fardellone, P; Grados, F; Kamel, S; Maamer, M; Mathieu, M; Morel, A; Sebert, JL, 2005)
"Hyperuricemia is common among patients with chronic kidney disease (CKD)."1.72Hyperuricemia is associated with secondary hyperparathyroidism in patients with chronic kidney disease. ( Coelho, VA; Costa, TEM; Elias, RM; Innecchi, MLR; Lauar, JC; Moysés, RMA, 2022)
"Vitamin D deficiency has been shown to be associated with coronary artery disease (CAD)."1.56The relationship between a combination of vitamin D deficiency and hyperuricemia and the severity of coronary artery disease in myocardial infarction patients. ( Akgül, F; Akgün, T; Çakır, MO; Can, M; Serbest, NG; Somuncu, MU; Tatar, FP; Tekin, A, 2020)
"Vitamin D deficiency is common in obesity; however, its contribution in the development of metabolic complications remains uncertain."1.46The potential impact of the hypovitaminosis D on metabolic complications in obese adolescents - Preliminary results. ( Janus, D; Kalicka-Kasperczyk, A; Starzyk, JB; Sztefko, K; Wojcik, M, 2017)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's0 (0.00)18.2507
2000's1 (4.76)29.6817
2010's11 (52.38)24.3611
2020's7 (33.33)2.80

Authors

AuthorsStudies
Costa, TEM1
Lauar, JC1
Innecchi, MLR1
Coelho, VA1
Moysés, RMA1
Elias, RM1
Chen, LY1
Ye, XH1
Cheng, JL1
Xue, Y1
Shao, J1
Krysiak, R1
Basiak, M1
Machnik, G1
Szkróbka, W1
Okopień, B1
Chiang, CH1
Chang, YJ1
He, SR1
Chao, JN1
Yang, CH1
Liu, YT1
Lin, KM1
Lu, CL1
Hung, KC1
Wu, PC1
Pan, CF1
Wu, CJ1
Syu, RS1
Chen, JS1
Hsiao, PJ1
Lu, KC1
Somuncu, MU1
Serbest, NG1
Akgül, F1
Çakır, MO1
Akgün, T1
Tatar, FP1
Can, M1
Tekin, A1
Isnuwardana, R1
Bijukchhe, S1
Thadanipon, K1
Ingsathit, A1
Thakkinstian, A1
Ibrahim, WN1
Younes, N1
Shi, Z1
Abu-Madi, MA1
Wojcik, M1
Janus, D1
Kalicka-Kasperczyk, A1
Sztefko, K1
Starzyk, JB1
Fayed, A1
El Nokeety, MM1
Heikal, AA1
Sadek, KM1
Hammad, H1
Abdulazim, DO1
Salem, MM1
Sharaf El Din, UA1
Tian, LQ1
Shi, WQ1
Zhou, Y1
Zhang, YW1
Zhang, ML1
Peng, H1
Li, H1
Li, C1
Chao, X1
Zhang, Q1
Zhang, Y1
Shrestha, S1
Shrestha, L1
Jha, DK1
Sanchis-Gomar, F1
Salvagno, GL1
Lippi, G1
Gradillas-García, A1
Álvarez, J1
Rubio, JA1
de Abajo, FJ1
Alemzadeh, R1
Kichler, J1
Cartaya, J1
Gupta, OT1
Sipahi, S1
Acikgoz, SB1
Genc, AB1
Yildirim, M1
Solak, Y1
Tamer, A1
GROEN, JJ1
ESHCHAR, J1
BEN-ISHAY, D1
ALKAN, WJ1
BENASSA, BI1
Brazier, M1
Grados, F1
Kamel, S1
Mathieu, M1
Morel, A1
Maamer, M1
Sebert, JL1
Fardellone, P1
al-Gauhari, AA1
al-Nagdy, SA1
el-Sabbagh, ME1
Eisa, EA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
STOP Vertigo: Supplementation of Vitamin D for Termination of Recurrences From Benign Paroxysmal Positional Vertigo[NCT05863949]860 participants (Anticipated)Interventional2023-07-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for uric acid and Deficiency, Vitamin D

ArticleYear
The Paradoxical Role of Uric Acid in Osteoporosis.
    Nutrients, 2019, Sep-05, Volume: 11, Issue:9

    Topics: Animals; Biomarkers; Bone and Bones; Bone Remodeling; Humans; Hyperparathyroidism, Secondary; Hyperu

2019
Association Between Vitamin D and Uric Acid in Adults: A Systematic Review and Meta-Analysis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:10

    Topics: Humans; Hyperuricemia; Uric Acid; Vitamin D; Vitamin D Deficiency; Vitamins

2020

Trials

2 trials available for uric acid and Deficiency, Vitamin D

ArticleYear
Inhibition of xanthine oxidase and exercise on serum uric acid, 25(OH)D3, and calcium concentrations.
    Clinical laboratory, 2014, Volume: 60, Issue:8

    Topics: Adult; Allopurinol; Athletes; Calcifediol; Calcium; Cellulose; Double-Blind Method; Enzyme Inhibitor

2014
Clinical and laboratory safety of one year's use of a combination calcium + vitamin D tablet in ambulatory elderly women with vitamin D insufficiency: results of a multicenter, randomized, double-blind, placebo-controlled study.
    Clinical therapeutics, 2005, Volume: 27, Issue:12

    Topics: Aged; Bone Density Conservation Agents; Calcium; Calcium Carbonate; Cholecalciferol; Creatine; Dieta

2005

Other Studies

17 other studies available for uric acid and Deficiency, Vitamin D

ArticleYear
Hyperuricemia is associated with secondary hyperparathyroidism in patients with chronic kidney disease.
    International urology and nephrology, 2022, Volume: 54, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Calcium; Cholecalciferol; Female; Furosemide; Humans; H

2022
The association between vitamin D levels and heart rate variability in patients with type 2 diabetes mellitus.
    Medicine, 2022, Aug-26, Volume: 101, Issue:34

    Topics: Diabetes Mellitus, Type 2; Heart Rate; Humans; Retrospective Studies; Uric Acid; Vitamin D; Vitamin

2022
Vitamin D Status Determines Cardiometabolic Effects of Cabergoline in Women with Elevated Prolactin Levels: A Pilot Study.
    Nutrients, 2023, May-14, Volume: 15, Issue:10

    Topics: C-Reactive Protein; Cabergoline; Cardiovascular Diseases; Female; Fibrinogen; Glucose; Humans; Hyper

2023
Association of 25(OH)-Vitamin D and metabolic factors with colorectal polyps.
    PloS one, 2023, Volume: 18, Issue:6

    Topics: Adenomatous Polyps; Adult; Colonic Polyps; Cross-Sectional Studies; Female; Humans; Hyperglycemia; M

2023
The relationship between a combination of vitamin D deficiency and hyperuricemia and the severity of coronary artery disease in myocardial infarction patients.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2020, Volume: 48, Issue:1

    Topics: Biomarkers; Coronary Artery Disease; Cross-Sectional Studies; Female; Humans; Hyperuricemia; Male; M

2020
Serum Uric Acid Level Is Positively Associated With Higher Bone Mineral Density at Multiple Skeletal Sites Among Healthy Qataris.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Antioxidants; Body Mass Index; Bone and Bones; Bone

2021
The potential impact of the hypovitaminosis D on metabolic complications in obese adolescents - Preliminary results.
    Annals of agricultural and environmental medicine : AAEM, 2017, Dec-23, Volume: 24, Issue:4

    Topics: Adolescent; Blood Pressure; Child; Female; Fibroblast Growth Factors; Humans; Male; Obesity; Poland;

2017
Urine albumin and serum uric acid are important determinants of serum 25 hydroxyvitamin D level in pre-dialysis chronic kidney disease patients.
    Renal failure, 2019, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Albumins; Albuminuria; Cross-Sectional Studies; Female; Glomerular Filtration Rat

2019
The Association of Serum Vitamin D Deficiency and Metabolic Risk Factors in Chinese Adults with Prediabetes: A Cross-Sectional Study.
    Journal of nutritional science and vitaminology, 2019, Volume: 65, Issue:3

    Topics: Adult; Aged; China; Cholesterol, HDL; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Pr

2019
Association between vitamin D insufficiency and elevated serum uric acid among middle-aged and elderly Chinese Han women.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adult; Aged; Asian People; Biomarkers; Blood Glucose; Fasting; Female; Humans; Hyperuricemia; Lipids

2013
Vitamin D status among individuals attended in Health Home Care Centre, Lalitpur, Nepal.
    Nepal Medical College journal : NMCJ, 2012, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Calcium; Cholecalciferol; Female; Hemoglobi

2012
[Relationship between vitamin D deficiency and metabolic syndrome in adult population of the Community of Madrid].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2015, Volume: 62, Issue:4

    Topics: Adult; Aged; Anthropometry; Blood Glucose; Cross-Sectional Studies; Diet; Disease Susceptibility; Fe

2015
Uric Acid-Induced Inflammation Is Mediated by the Parathyroid Hormone:25-Hydroxyvitamin D Ratio in Obese Adolescents.
    Metabolic syndrome and related disorders, 2016, Volume: 14, Issue:3

    Topics: Adolescent; Female; Humans; Inflammation; Male; Metabolic Syndrome; Parathyroid Hormone; Pediatric O

2016
Uric Acid, Parathyroid Hormone, and Vitamin D: New Players in an Old Game.
    Metabolic syndrome and related disorders, 2016, Volume: 14, Issue:3

    Topics: Calcium; Humans; Parathyroid Hormone; Uric Acid; Vitamin D; Vitamin D Deficiency; Vitamins

2016
The Association of Vitamin D Status and Vitamin D Replacement Therapy with Glycemic Control, Serum Uric Acid Levels, and Microalbuminuria in Patients with Type 2 Diabetes and Chronic Kidney Disease.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2017, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuminuria; Blood Glucose; Creatinine; Diabetes Mellitu

2017
OSTEOMALACIA AMONG THE BEDOUIN OF THE NEGEV DESERT; CLINICAL AND BIOCHEMICAL OBSERVATIONS.
    Archives of internal medicine, 1965, Volume: 116

    Topics: Alkaline Phosphatase; Arabs; Blood; Calcium; Clothing; Creatine; Creatinine; Desert Climate; Drug Th

1965
Biochemical studies on some aspects of protein metabolism in vitamin-D deficient rats.
    Comparative biochemistry and physiology. A, Comparative physiology, 1974, Mar-01, Volume: 47, Issue:3

    Topics: Amino Acids; Animals; Blood Proteins; Body Water; Body Weight; Creatinine; Female; Male; Rats; Serum

1974