uric acid has been researched along with Deficiency, Glucosephosphatase in 46 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Studies were performed to determine whether hypoglycemia or the glucagon response to hypoglycemia increases uric acid production in glycogen storage disease type I (glucose-6-phosphatase deficiency)." | 7.67 | Hyperuricemia in glycogen storage disease type I. Contributions by hypoglycemia and hyperglucagonemia to increased urate production. ( Cohen, JL; Faller, J; Fox, IH; Vinik, A, 1985) |
| "Hyperuricemia (serum urate level >7 mg/dL) is caused by accelerated generation of uric acid and/or impaired excretion in the kidney." | 4.84 | [Definition and classification of hyperuricemia]. ( Yamamoto, T, 2008) |
| "Carbohydrate requirements (milligrams per kilogram per minute), triglyceride and uric acid levels, liver ultrasonography, and creatinine clearance were investigated before, during, and after pregnancy." | 3.74 | Pregnancies in glycogen storage disease type Ia. ( Martens, DH; Merkel, M; Rake, JP; Sauer, PJ; Schwarz, M; Smit, GP; Ullrich, K; Weinstein, DA, 2008) |
| "Studies were performed to determine whether hypoglycemia or the glucagon response to hypoglycemia increases uric acid production in glycogen storage disease type I (glucose-6-phosphatase deficiency)." | 3.67 | Hyperuricemia in glycogen storage disease type I. Contributions by hypoglycemia and hyperglucagonemia to increased urate production. ( Cohen, JL; Faller, J; Fox, IH; Vinik, A, 1985) |
| "Hepatomegaly was present in 39 out of 40, while 11 out of 27 reported patients had marked hepatomegaly (> 10 cm below the costal margin in the midclavicular line)." | 1.29 | The long-term outcome of patients with glycogen storage disease type Ia. ( Smit, GP, 1993) |
| "In addition, a single patient with von Gierke's disease showed a marked increase in the plasma activity of this enzyme, relative to that apparent in normal subjects." | 1.29 | Determination of human plasma xanthine oxidase activity by high-performance liquid chromatography. ( Higashino, K; Hiroishi, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T, 1996) |
| "Seven patients with glycogen disease type I have been treated with nocturnal intragastric feeding combined with frequent daytime feeding." | 1.27 | Glycogen storage disease type I. Results of treatment with frequent daytime feeding, combined with nocturnal intragastric feeding and with administration of an alpha-glucosidase inhibitor. ( Gröbe, H; Ullrich, K, 1983) |
| "Glycogen storage disease type IB was detected by comparing glucose-6-phosphatase (EC 3." | 1.27 | Glycogen storage disease type I: laboratory data and diagnosis. ( Allam, CK; Bitar, JG; Wakid, NW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (63.04) | 18.7374 |
| 1990's | 9 (19.57) | 18.2507 |
| 2000's | 6 (13.04) | 29.6817 |
| 2010's | 2 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, WT | 1 |
| Pan, CJ | 1 |
| Lee, EJ | 1 |
| Westphal, H | 1 |
| Chou, JY | 1 |
| Das, AM | 1 |
| Lücke, T | 1 |
| Meyer, U | 1 |
| Hartmann, H | 1 |
| Illsinger, S | 1 |
| Adenwalla, HN | 1 |
| O'Connor, CR | 1 |
| Yamasaki, T | 1 |
| Mineo, I | 1 |
| Di Rocco, M | 1 |
| Calevo, MG | 1 |
| Taro', M | 1 |
| Melis, D | 1 |
| Allegri, AE | 1 |
| Parenti, G | 1 |
| Martens, DH | 1 |
| Rake, JP | 1 |
| Schwarz, M | 1 |
| Ullrich, K | 3 |
| Weinstein, DA | 1 |
| Merkel, M | 1 |
| Sauer, PJ | 1 |
| Smit, GP | 2 |
| Yamamoto, T | 3 |
| Nuki, G | 1 |
| Gröbe, H | 1 |
| Pritchard, MH | 1 |
| Wolfsdorf, JI | 3 |
| Crigler, JF | 3 |
| Moriwaki, Y | 2 |
| Takahashi, S | 1 |
| Tsutsumi, Z | 1 |
| Yamakita, J | 1 |
| Nasako, Y | 1 |
| Hiroishi, K | 1 |
| Higashino, K | 2 |
| Wittenstein, B | 1 |
| Klein, M | 1 |
| Finckh, B | 1 |
| Kohlschütter, A | 1 |
| Spahr, RC | 1 |
| Stormont, D | 1 |
| Davies, C | 1 |
| Emmerson, BT | 2 |
| Watts, RW | 1 |
| Roe, TF | 1 |
| Kogut, MD | 1 |
| Benke, PJ | 1 |
| Gold, S | 1 |
| Greene, HL | 2 |
| Wilson, FA | 1 |
| Hefferan, P | 1 |
| Terry, AB | 1 |
| Moran, JR | 1 |
| Slonim, AE | 2 |
| Claus, TH | 1 |
| Burr, IM | 2 |
| Ekert, H | 1 |
| Waters, KD | 1 |
| Marinello, E | 1 |
| Pompucci, G | 1 |
| Riario-Sforza, G | 1 |
| Leonard, JV | 1 |
| Francis, DE | 1 |
| Dunger, DB | 1 |
| O'Neill, JA | 1 |
| Ravenscroft, PJ | 1 |
| Bartolozzi, G | 1 |
| Bernini, G | 1 |
| Marianelli, L | 1 |
| Nassi, P | 1 |
| Caimi, G | 1 |
| Lo Presti, R | 1 |
| Chen, YT | 2 |
| Feinstein, KA | 1 |
| Coleman, RA | 2 |
| Effmann, EL | 1 |
| Scheinman, JI | 1 |
| Park, HK | 1 |
| Roe, CR | 1 |
| Plotkin, RA | 1 |
| Laffel, LM | 1 |
| Rudlin, CR | 1 |
| Wakid, NW | 1 |
| Bitar, JG | 1 |
| Allam, CK | 1 |
| Cohen, JL | 1 |
| Vinik, A | 1 |
| Faller, J | 1 |
| Fox, IH | 2 |
| Pennes, DR | 1 |
| Martel, W | 1 |
| Dosman, J | 1 |
| Crawhall, JC | 1 |
| Klassen, GA | 1 |
| Mamer, OA | 1 |
| Neumann, P | 1 |
| Boyle, JA | 1 |
| Seegmiller, JE | 3 |
| Howell, RR | 2 |
| Fine, RN | 1 |
| Strauss, J | 1 |
| Donnell, GN | 1 |
| Alepa, FP | 1 |
| Klinenberg, JR | 1 |
| Zuppinger, K | 1 |
| Papenberg, J | 1 |
| Schürch, P | 1 |
| von Wartburg, JP | 1 |
| Colombo, JP | 1 |
| Rossi, E | 1 |
| Benedetti, A | 1 |
| Bucciante, G | 1 |
| Cattano, G | 1 |
| Nardini, A | 1 |
| Neubaur, J | 2 |
| Willms, B | 2 |
| Söling, HD | 1 |
| Creutzfeldt, W | 1 |
| Matschke, I | 1 |
| Wolf, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anaplerotic Therapy Using Triheptanoin for Patients With Glycogen Storage Disease Type I[NCT03665636] | Early Phase 1 | 4 participants (Actual) | Interventional | 2020-10-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for uric acid and Deficiency, Glucosephosphatase
| Article | Year |
|---|---|
[Secondary hyperuricemia in glycogen storage disease types I, III, V and VII].
Topics: Glycogen Storage Disease Type I; Glycogen Storage Disease Type III; Glycogen Storage Disease Type V; | 2003 |
[Definition and classification of hyperuricemia].
Topics: Alcohol Drinking; Diet, Reducing; Fructose; Glucose-6-Phosphatase; Glycogen Storage Disease Type I; | 2008 |
Human purine metabolism: some recent advances and relationships with immunodeficiency.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Glycogen Storage Disease Type I; Gout; Human | 1983 |
Gout and pseudogout: crystal-induced arthropathies.
Topics: Calcium Pyrophosphate; Chondrocalcinosis; Crystallization; Diuretics; Ethanol; Glycogen Storage Dise | 1981 |
Metabolic causes of renal stone formation.
Topics: Adenine Phosphoribosyltransferase; Cystinuria; Glycogen Storage Disease Type I; Humans; Hypoxanthine | 1977 |
[Screening for enzyme abnormality causing hyperuricemia].
Topics: Glycogen Storage Disease Type I; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrom | 1991 |
[Physiopathological aspects of secondary hyperuricemia].
Topics: Acute Disease; Coronary Disease; Drug-Related Side Effects and Adverse Reactions; Fructose; Glycogen | 1991 |
Selected aspects of the aetiology, pathogenesis and treatment of disorders of purine metabolism.
Topics: Allopurinol; Colchicine; Glycogen Storage Disease Type I; Gout; Humans; Lesch-Nyhan Syndrome; Metabo | 1971 |
2 trials available for uric acid and Deficiency, Glucosephosphatase
| Article | Year |
|---|---|
Biochemical evidence for the requirement of continuous glucose therapy in young adults with type 1 glycogen storage disease.
Topics: Adolescent; Adult; Blood Glucose; Female; Glucose; Glycogen Storage Disease Type I; Humans; Hypoglyc | 1994 |
Continuous glucose for treatment of patients with type 1 glycogen-storage disease: comparison of the effects of dextrose and uncooked cornstarch on biochemical variables.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Cholesterol; Female; Glucose; Glycogen Storage D | 1990 |
36 other studies available for uric acid and Deficiency, Glucosephosphatase
| Article | Year |
|---|---|
Generation of mice with a conditional allele for G6pc.
Topics: Alleles; Animals; Blood Glucose; Cholesterol; Disease Models, Animal; DNA Primers; Gene Components; | 2009 |
Glycogen storage disease type 1: impact of medium-chain triglycerides on metabolic control and growth.
Topics: Adult; Body Height; Body Weight; Child, Preschool; Diet; Dietary Carbohydrates; Dietary Fats; Energy | 2010 |
Catastrophic axial gout causing paraplegia in a patient with glycogen storage disease.
Topics: Adult; Catastrophic Illness; Drug Therapy, Combination; Febuxostat; Glycogen Storage Disease Type I; | 2011 |
Hepatocellular adenoma and metabolic balance in patients with type Ia glycogen storage disease.
Topics: Adenoma, Liver Cell; Adolescent; Adult; Body Mass Index; Case-Control Studies; Child; Child, Prescho | 2008 |
Pregnancies in glycogen storage disease type Ia.
Topics: Adult; Dietary Carbohydrates; Female; Glycogen Storage Disease Type I; Humans; Infant, Newborn; Preg | 2008 |
Glycogen storage disease type I. Results of treatment with frequent daytime feeding, combined with nocturnal intragastric feeding and with administration of an alpha-glucosidase inhibitor.
Topics: Acarbose; Alanine; Aspartate Aminotransferases; Blood Glucose; Child; Enteral Nutrition; Female; Gly | 1983 |
The long-term outcome of patients with glycogen storage disease type Ia.
Topics: Adenoma; Adolescent; Adult; Aged; Apolipoproteins; Blood Glucose; Child; Cholesterol; Female; Glycog | 1993 |
Determination of human plasma xanthine oxidase activity by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ethanol; Glycogen Storage Disease Type I; Gout; Heparin; Hepat | 1996 |
Plasma antioxidants in pediatric patients with glycogen storage disease, diabetes mellitus, and hypercholesterolemia.
Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Child; Child, Preschool; Cholesterol; Chromatography | 2002 |
Von Gierke's disease: a review.
Topics: Allopurinol; Bicarbonates; Blood Glucose; Diazoxide; Gluconeogenesis; Glucose-6-Phosphatase; Glycoge | 1976 |
Urate production in heterozygotes for glucose-6-phosphatase deficiency.
Topics: Adult; Blood Platelets; Child, Preschool; Erythrocytes; Female; Glucose-6-Phosphatase; Glucosephosph | 1976 |
The pathogenesis of hyperuricemia in glycogen storage disease, type I.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Fructose; Glucagon; Glycogen Storage Disease Typ | 1977 |
Uric acid metabolism in therapy of glycogen storage disease type I.
Topics: Child; Dietary Carbohydrates; Glycine; Glycogen Storage Disease Type I; Humans; Intubation, Gastroin | 1978 |
ATP depletion, a possible role in the pathogenesis of hyperuricemia in glycogen storage disease type I.
Topics: Adenosine Triphosphate; Adolescent; Adult; Animals; Child; Child, Preschool; Glucagon; Glycogen Stor | 1978 |
Hematologic emergencies in children.
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Asp | 1978 |
[Interrelationship between purine, carbohydrate, lipid and aminoacid metabolism, in hyperuricaemia and gout (author's transl)].
Topics: Alcoholic Intoxication; Alcoholism; Amino Acids; Carbohydrate Metabolism; Diabetes Mellitus; Fructos | 1978 |
The dietary management of hepatic glycogen storage disease.
Topics: Blood Glucose; Cholesterol; Glucose; Glycogen Storage Disease; Glycogen Storage Disease Type I; Huma | 1979 |
Continuous nocturnal intragastric feeding for management of type 1 glycogen-storage disease.
Topics: Adolescent; Aspartate Aminotransferases; Blood Glucose; Child; Cholesterol; Clofibrate; Eating; Ente | 1976 |
Abnormal renal urate homeostasis in systemic disorders.
Topics: Alcoholism; Diabetes Mellitus; Female; Fructose Intolerance; Glomerular Filtration Rate; Glycogen St | 1975 |
[Type I glycogenosis. Description of 2 cases with hyperuricemia].
Topics: Biopsy; Child; Galactose; Glucagon; Glucose Tolerance Test; Glycogen Storage Disease Type I; Gout; H | 1975 |
Variability of renal length in type I glycogen storage disease.
Topics: Adolescent; Child; Child, Preschool; Cholesterol; Female; Glycogen Storage Disease Type I; Humans; K | 1990 |
Amelioration of proximal renal tubular dysfunction in type I glycogen storage disease with dietary therapy.
Topics: Adolescent; Adult; beta 2-Microglobulin; Blood Glucose; Cholesterol; Dietary Carbohydrates; Female; | 1990 |
Physical growth and development of children with type 1 glycogen-storage disease: comparison of the effects of long-term use of dextrose and uncooked cornstarch.
Topics: Adolescent; Blood Glucose; Body Height; Body Weight; Child; Child, Preschool; Cholesterol; Female; G | 1990 |
Glycogen storage disease type I: laboratory data and diagnosis.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Child, Preschool; Cholesterol; Female; Glu | 1987 |
Hyperuricemia in glycogen storage disease type I. Contributions by hypoglycemia and hyperglucagonemia to increased urate production.
Topics: Adenosine Triphosphate; Adolescent; Adult; Female; Glucagon; Glucose; Glycogen Storage Disease Type | 1985 |
Hyperuricemia and gout.
Topics: Adolescent; Age Factors; Arthritis; Arthrography; Bone Diseases; Child; Diagnosis, Differential; Fem | 1986 |
Adenosine triphosphate degradation in specific disease.
Topics: Adenine; Adenosine Triphosphate; Biotransformation; Carnitine O-Palmitoyltransferase; Ethanol; Fruct | 1985 |
Urinary excretion of C6-C10 dicarboxylic acids in glycogen storage disease types I and 3.
Topics: Adolescent; Blood Glucose; Body Height; Body Weight; Carbon Radioisotopes; Child; Cholesterol; Chrom | 1974 |
The interrelationship of glycogen storage disease and gout.
Topics: Adult; Child; Glycogen Storage Disease Type I; Gout; Humans; Kidney Function Tests; Lactates; Uric A | 1965 |
Hyperuricemia in glycogen-storage disease type 1.
Topics: Adolescent; Adult; Child; Child, Preschool; Glucose; Glycogen Storage Disease; Glycogen Storage Dise | 1966 |
Relationships between glycogen storage disease and tophaceous gout.
Topics: Adult; Female; Glucose Tolerance Test; Glycogen Storage Disease Type I; Gout; Humans; Inulin; Lactat | 1967 |
[Increased alcohol oxydation in glycogenosis type I].
Topics: Adolescent; Adult; Blood Glucose; Child; Ethanol; Fatty Acids, Nonesterified; Glycerides; Glycogen S | 1967 |
[Gout in the evolution of Von Gierke's disease].
Topics: Adolescent; Adult; Allopurinol; Child; Female; Glycogen Storage Disease; Glycogen Storage Disease Ty | 1969 |
[Gout as a complication of adult glycogen storage disease].
Topics: Adolescent; Adult; Blood Glucose; Female; Glycogen Storage Disease Type I; Gout; Humans; Lactates; M | 1969 |
Metabolic aberrations in gout.
Topics: Female; Glycogen Storage Disease Type I; Gout; Humans; Kidney; Kidney Calculi; Kidney Diseases; Male | 1970 |
[Metabolism studies in children and young adults with glycogenoses].
Topics: Adolescent; Adult; Child; Fatty Acids; Glucagon; Glucosidases; Glucosyltransferases; Glycogen Storag | 1969 |