uric acid has been researched along with Death, Sudden, Cardiac in 7 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compared with the placebo group, the empagliflozin group showed significant decreases in body weight, systolic blood pressure, and uric acid." | 9.34 | Effects of empagliflozin versus placebo on cardiac sympathetic activity in acute myocardial infarction patients with type 2 diabetes mellitus: the EMBODY trial. ( Asai, K; Hoshika, Y; Ishikawa, M; Iwasaki, YK; Kodani, E; Kubota, Y; Maruyama, M; Miyamoto, M; Miyauchi, Y; Mozawa, K; Ogano, M; Shimizu, W; Takano, H; Tanabe, J; Tara, S; Tokita, Y; Tsukada, Y; Yamamoto, T; Yodogawa, K, 2020) |
| "The uric acid (UA) level is related to cardiac events and mortality, but little is known about the clinical significance of serum UA with regard to the ventricular tachyarrhythmia (VT) risk in patients with heart failure." | 7.88 | Association between Serum Uric Acid Level and Ventricular Tachyarrhythmia in Heart Failure Patients with Implantable Cardioverter-Defibrillator. ( Kamioka, M; Kaneshiro, T; Matsumoto, Y; Nodera, M; Ohira, T; Suzuki, H; Takeishi, Y; Yoshihisa, A, 2018) |
| "In patients with coronary artery disease (CAD), elevated serum uric acid (SUA) levels may predict worse cardiovascular outcomes." | 7.75 | Serum uric acid for risk stratification of patients with coronary artery disease. ( Behar, S; Boyko, V; Brodov, Y; Chouraqui, P; Goldenberg, I; Mandelzweig, L, 2009) |
| " Compared with the placebo group, the empagliflozin group showed significant decreases in body weight, systolic blood pressure, and uric acid." | 5.34 | Effects of empagliflozin versus placebo on cardiac sympathetic activity in acute myocardial infarction patients with type 2 diabetes mellitus: the EMBODY trial. ( Asai, K; Hoshika, Y; Ishikawa, M; Iwasaki, YK; Kodani, E; Kubota, Y; Maruyama, M; Miyamoto, M; Miyauchi, Y; Mozawa, K; Ogano, M; Shimizu, W; Takano, H; Tanabe, J; Tara, S; Tokita, Y; Tsukada, Y; Yamamoto, T; Yodogawa, K, 2020) |
| "This pharmacologic protection trial was conducted to test the hypothesis that allopurinol, a scavenger and inhibitor of oxygen free radical production, could reduce death, seizures, coma, and cardiac events in infants who underwent heart surgery using deep hypothermic circulatory arrest (DHCA)." | 5.09 | Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest. ( Clancy, RR; Gaynor, JW; Goin, JE; Hirtz, DG; Jacobs, ML; Mahle, WT; McGaurn, SA; Murphy, JD; Nicolson, SC; Norwood, WI; Spray, TL; Steven, JM; Wernovsky, G, 2001) |
| "The uric acid (UA) level is related to cardiac events and mortality, but little is known about the clinical significance of serum UA with regard to the ventricular tachyarrhythmia (VT) risk in patients with heart failure." | 3.88 | Association between Serum Uric Acid Level and Ventricular Tachyarrhythmia in Heart Failure Patients with Implantable Cardioverter-Defibrillator. ( Kamioka, M; Kaneshiro, T; Matsumoto, Y; Nodera, M; Ohira, T; Suzuki, H; Takeishi, Y; Yoshihisa, A, 2018) |
| "In patients with coronary artery disease (CAD), elevated serum uric acid (SUA) levels may predict worse cardiovascular outcomes." | 3.75 | Serum uric acid for risk stratification of patients with coronary artery disease. ( Behar, S; Boyko, V; Brodov, Y; Chouraqui, P; Goldenberg, I; Mandelzweig, L, 2009) |
| "Participants were followed for sudden cardiac death or incident CHD (i." | 1.62 | Higher Serum Urate Levels Are Associated With an Increased Risk for Sudden Cardiac Death. ( Armstrong, ND; Bridges, SL; Chaudhary, NS; Colantonio, LD; Curtis, JR; Gaffo, A; Howard, G; Irvin, MR; Lang, L; Merriman, TR; Muntner, P; Plante, TB; Reynolds, RJ; Saag, KG; Safford, MM; Singh, JA; Soliman, EZ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Shimizu, W | 1 |
| Kubota, Y | 1 |
| Hoshika, Y | 1 |
| Mozawa, K | 1 |
| Tara, S | 1 |
| Tokita, Y | 1 |
| Yodogawa, K | 1 |
| Iwasaki, YK | 1 |
| Yamamoto, T | 1 |
| Takano, H | 1 |
| Tsukada, Y | 1 |
| Asai, K | 1 |
| Miyamoto, M | 1 |
| Miyauchi, Y | 1 |
| Kodani, E | 1 |
| Ishikawa, M | 1 |
| Maruyama, M | 1 |
| Ogano, M | 1 |
| Tanabe, J | 1 |
| Colantonio, LD | 1 |
| Reynolds, RJ | 1 |
| Merriman, TR | 1 |
| Gaffo, A | 1 |
| Singh, JA | 1 |
| Plante, TB | 1 |
| Chaudhary, NS | 1 |
| Armstrong, ND | 1 |
| Soliman, EZ | 1 |
| Curtis, JR | 1 |
| Bridges, SL | 1 |
| Lang, L | 1 |
| Howard, G | 1 |
| Safford, MM | 1 |
| Saag, KG | 1 |
| Muntner, P | 1 |
| Irvin, MR | 1 |
| Özyılmaz, S | 1 |
| Satılmışoğlu, MH | 1 |
| Gül, M | 1 |
| Uyarel, H | 1 |
| Serdar, OA | 1 |
| Nodera, M | 1 |
| Suzuki, H | 1 |
| Matsumoto, Y | 1 |
| Kamioka, M | 1 |
| Kaneshiro, T | 1 |
| Yoshihisa, A | 1 |
| Ohira, T | 1 |
| Takeishi, Y | 1 |
| Brodov, Y | 1 |
| Chouraqui, P | 1 |
| Goldenberg, I | 1 |
| Boyko, V | 1 |
| Mandelzweig, L | 1 |
| Behar, S | 1 |
| Silbernagel, G | 1 |
| Hoffmann, MM | 1 |
| Grammer, TB | 1 |
| Boehm, BO | 1 |
| März, W | 1 |
| Clancy, RR | 1 |
| McGaurn, SA | 1 |
| Goin, JE | 1 |
| Hirtz, DG | 1 |
| Norwood, WI | 1 |
| Gaynor, JW | 1 |
| Jacobs, ML | 1 |
| Wernovsky, G | 1 |
| Mahle, WT | 1 |
| Murphy, JD | 1 |
| Nicolson, SC | 1 |
| Steven, JM | 1 |
| Spray, TL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation[NCT02519335] | Phase 1 | 12 participants (Actual) | Interventional | 2014-09-30 | Terminated (stopped due to PI no longer at this facility) | ||
| Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery[NCT04997291] | Phase 1 | 12 participants (Anticipated) | Interventional | 2021-04-09 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for uric acid and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Effects of empagliflozin versus placebo on cardiac sympathetic activity in acute myocardial infarction patients with type 2 diabetes mellitus: the EMBODY trial.
Topics: 3-Iodobenzylguanidine; Aged; Benzhydryl Compounds; Blood Pressure; Body Weight; Death, Sudden, Cardi | 2020 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
5 other studies available for uric acid and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Higher Serum Urate Levels Are Associated With an Increased Risk for Sudden Cardiac Death.
Topics: Adult; Black or African American; Coronary Disease; Death, Sudden, Cardiac; Female; Humans; Incidenc | 2021 |
Evaluation of the association between serum uric acid level andthe predicted risk score of sudden cardiac death in five years in patients with hypertrophic cardiomyopathy.
Topics: Adolescent; Adult; Aged; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Female; Humans; Male; | 2018 |
Association between Serum Uric Acid Level and Ventricular Tachyarrhythmia in Heart Failure Patients with Implantable Cardioverter-Defibrillator.
Topics: Aged; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Female; Heart Failur | 2018 |
Serum uric acid for risk stratification of patients with coronary artery disease.
Topics: Aged; Biomarkers; Coronary Artery Disease; Death, Sudden, Cardiac; Female; Humans; Male; Middle Aged | 2009 |
Uric acid is predictive of cardiovascular mortality and sudden cardiac death in subjects referred for coronary angiography.
Topics: Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Death, Sudden, Cardiac; Fema | 2013 |