uric acid has been researched along with Deafness in 15 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Deafness: A general term for the complete loss of the ability to hear from both ears.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two members of a Spanish family were studied: an eight-year-old boy (Patient 1) with tophaceous gout, purine nucleotide and uric acid overproduction, and sensorineural deafness, and his 27-year-old mother (Patient 2), who had gout." | 7.67 | Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness. ( Becker, MA; Jimenez, ML; Kim, M; Mateos, FA; Puig, JG; Simmonds, HA, 1988) |
| " Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months." | 6.64 | Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. ( Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA, 1974) |
| "The overactivity of PRPP synthetase is transmitted as a sex-linked abnormality, being characterized by uric acid overproduction and, in some patients, by muscular hypotonia, neurosensitive deafness and/or ataxia." | 3.68 | [Metabolism of purine nucleotides in the central nervous system in patients with phosphoribosylpyrophosphate synthetase hyperactivity and neurosensory deafness]. ( García Neito, V; García Puig, J; López Jiménez, M; Mateos Antón, F; Ramos Hernández, T; Sebastián Melián, J, 1990) |
| "Two members of a Spanish family were studied: an eight-year-old boy (Patient 1) with tophaceous gout, purine nucleotide and uric acid overproduction, and sensorineural deafness, and his 27-year-old mother (Patient 2), who had gout." | 3.67 | Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness. ( Becker, MA; Jimenez, ML; Kim, M; Mateos, FA; Puig, JG; Simmonds, HA, 1988) |
| " Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months." | 2.64 | Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. ( Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sahin, A | 1 |
| Kilic, K | 1 |
| Sakat, MS | 1 |
| Melikoglu, MA | 1 |
| Sarihan, K | 1 |
| MONTANDON, A | 1 |
| Simmonds, HA | 4 |
| Webster, DR | 3 |
| Wilson, J | 3 |
| Lingham, S | 1 |
| Potter, CF | 1 |
| Fairbanks, LD | 1 |
| Martin, H | 1 |
| Boulud, B | 1 |
| Martin, C | 1 |
| Romanet, P | 1 |
| Wilke, H | 1 |
| Grossgerge, H | 1 |
| Haubold, E | 1 |
| Kahlke, W | 1 |
| Frahm, H | 1 |
| Regler, B | 1 |
| López Jiménez, M | 1 |
| García Puig, J | 1 |
| Mateos Antón, F | 1 |
| Ramos Hernández, T | 1 |
| Sebastián Melián, J | 1 |
| García Neito, V | 1 |
| Jiménez, ML | 2 |
| Puig, JG | 2 |
| Mateos, FA | 2 |
| Ramos, TH | 1 |
| Melián, JS | 1 |
| Nieto, VG | 1 |
| Becker, MA | 2 |
| Kim, M | 1 |
| Lingam, S | 1 |
| Huskisson, EC | 1 |
| Wojtulewski, JA | 1 |
| Berry, H | 1 |
| Scott, J | 1 |
| Hart, FD | 1 |
| Balme, HW | 1 |
| Goldstein, JL | 1 |
| Fialkow, PJ | 1 |
| Amer, M | 1 |
| el-Shazly, M | 1 |
| Rosenberg, AL | 1 |
| Bergstrom, L | 1 |
| Troost, BT | 1 |
| Bartholomew, BA | 1 |
| Weinstein, RL | 1 |
| Kliman, B | 1 |
| Scully, RE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of a Cold Water Immersion (CWI) on Pain in People With Gouty Arthritis: A Community Based Randomized Controlled Trial[NCT04587544] | 76 participants (Actual) | Interventional | 2019-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for uric acid and Deafness
| Article | Year |
|---|---|
Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin.
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Body Temperature; Clinical Trials as Topic; Deafness; | 1974 |
14 other studies available for uric acid and Deafness
| Article | Year |
|---|---|
Early hearing loss detection in gout using extended high frequency audiometry.
Topics: Audiometry; Audiometry, Pure-Tone; Auditory Threshold; Cross-Sectional Studies; Deafness; Gout; Hear | 2022 |
[Uric acid diathesis and deafness].
Topics: Deafness; Disease Susceptibility; Hearing; Hearing Disorders; Hearing Loss; Humans; Uric Acid | 1953 |
An X-linked syndrome characterised by hyperuricaemia, deafness, and neurodevelopmental abnormalities.
Topics: Adenine Phosphoribosyltransferase; Adult; Child; Child, Preschool; Deafness; Female; Genetic Linkage | 1982 |
Evidence of a new syndrome involving hereditary uric acid over-production, neurological complications and deafness.
Topics: Clinical Laboratory Techniques; Deafness; Erythrocytes; Female; Humans; Infant, Newborn; Kinetics; M | 1984 |
[Internal ear deafness and metabolic disorders].
Topics: Adult; Aged; Deafness; Diabetes Complications; Female; Humans; Hyperglycemia; Labyrinth Diseases; Ma | 1976 |
[Frequency and distribution of risk factors in hearing loss].
Topics: Adolescent; Adult; Aged; Deafness; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; | 1977 |
[Metabolism of purine nucleotides in the central nervous system in patients with phosphoribosylpyrophosphate synthetase hyperactivity and neurosensory deafness].
Topics: Adult; Brain; Child; Deafness; Female; Genetic Carrier Screening; Gout; Homozygote; Humans; Hypoxant | 1990 |
Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity.
Topics: Adolescent; Adult; Child; Child, Preschool; Deafness; Female; Humans; Hypoxanthines; Inosine; Male; | 1989 |
Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
Topics: Adult; Child; Deafness; Female; Fibroblasts; Gout; Humans; Male; Phosphotransferases; Purine Nucleot | 1988 |
An inborn error of purine metabolism, deafness and neurodevelopmental abnormality.
Topics: Deafness; Erythrocytes; Female; Guanosine Triphosphate; Humans; Infant; Infant, Newborn; Intellectua | 1985 |
The Alström syndrome. Report of three cases with further delineation of the clinical, pathophysiological, and genetic aspects of the disorder.
Topics: Adolescent; Adult; Albuminuria; Blood Cell Count; Blood Urea Nitrogen; Child; Complement System Prot | 1973 |
The association of familial hyperbetalipoproteinaemia with Waardenburg's syndrome.
Topics: Abnormalities, Multiple; Adolescent; Adult; Blood Glucose; Child; Cholesterol; Chromosome Aberration | 1974 |
Hyperuricemia and neurologic deficits. A family study.
Topics: Adult; Ataxia; Deafness; Erythrocytes; Female; Humans; Kidney Diseases; Kidney Function Tests; Male; | 1970 |
Familial syndrome of primary testicular insufficiency with normal virilization, blindness, deafness and metabolic abnormalities.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Blindness; Body Heigh | 1969 |