uric acid has been researched along with Crystal Arthritis in 11 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is now well established that intra-articular deposition of endogenous particulates, such as osteoarthritis-associated basic calcium phosphate crystals, gout-associated monosodium urate crystals, and calcium deposition disease-associated calcium pyrophosphate crystals, contributes to joint destruction through the production of cartilage-degrading enzymes and pro-inflammatory cytokines." | 4.98 | Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets. ( Dunne, A; Mahon, OR, 2018) |
| " In the present study, we aimed to explore the relationship between TAK1 and gout as well as the effects of resveratrol on TAK1 activity and MSU crystal-induced inflammation." | 3.91 | Resveratrol attenuates the MSU crystal-induced inflammatory response through the inhibition of TAK1 activity. ( He, Y; Li, H; Ou, G; Ren, L; Yang, X; Zeng, M, 2019) |
| "Crystal arthritis is the most common type of inflammatory arthritis, and fractures contribute to significant morbidity and mortality, therefore, the relationship between the two is of clinical importance." | 2.58 | Crystalline arthropathy and bone health. ( Chang, I; Gazeley, D, 2018) |
| "Therefore crystal arthropathies could be seen as an auto-inflammatory condition." | 1.51 | [Crystal arthropathies]. ( Reuss-Borst, M; Tausche, AK, 2019) |
| "Rapid diagnosis of septic arthritis from Gram-stain microscopy is limited by an inherent false-negative rate of 25-78%." | 1.48 | The Limitations of Gram-stain Microscopy of Synovial Fluid in Concomitant Septic and Crystal Arthritis. ( Atkinson, HD; Stirling, P; Tahir, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Lan, Z | 1 |
| Chen, L | 1 |
| Feng, J | 1 |
| Xie, Z | 1 |
| Liu, Z | 1 |
| Wang, F | 1 |
| Liu, P | 1 |
| Yue, X | 1 |
| Du, L | 1 |
| Zhao, Y | 1 |
| Yang, P | 1 |
| Luo, J | 1 |
| Zhu, Z | 1 |
| Hu, X | 1 |
| Cao, L | 1 |
| Lu, P | 1 |
| Sah, R | 1 |
| Lavine, K | 1 |
| Kim, B | 1 |
| Hu, H | 1 |
| Jarraya, M | 1 |
| Roemer, F | 1 |
| Kwoh, CK | 1 |
| Guermazi, A | 1 |
| Meyer, MM | 1 |
| Marks, LA | 1 |
| Aslam, F | 1 |
| Stirling, P | 1 |
| Tahir, M | 1 |
| Atkinson, HD | 1 |
| Chang, I | 1 |
| Gazeley, D | 1 |
| Bursill, D | 1 |
| Taylor, WJ | 1 |
| Terkeltaub, R | 1 |
| Kuwabara, M | 1 |
| Merriman, TR | 1 |
| Grainger, R | 1 |
| Pineda, C | 1 |
| Louthrenoo, W | 1 |
| Edwards, NL | 1 |
| Andrés, M | 1 |
| Vargas-Santos, AB | 1 |
| Roddy, E | 1 |
| Pascart, T | 1 |
| Lin, CT | 1 |
| Perez-Ruiz, F | 1 |
| Tedeschi, SK | 1 |
| Kim, SC | 1 |
| Harrold, LR | 1 |
| McCarthy, G | 1 |
| Kumar, N | 1 |
| Chapman, PT | 1 |
| Tausche, AK | 2 |
| Vazquez-Mellado, J | 1 |
| Gutierrez, M | 1 |
| da Rocha Castelar-Pinheiro, G | 1 |
| Richette, P | 1 |
| Pascual, E | 1 |
| Fisher, MC | 1 |
| Burgos-Vargas, R | 1 |
| Robinson, PC | 1 |
| Singh, JA | 1 |
| Jansen, TL | 1 |
| Saag, KG | 1 |
| Slot, O | 1 |
| Uhlig, T | 1 |
| Solomon, DH | 1 |
| Keenan, RT | 1 |
| Scire, CA | 1 |
| Biernat-Kaluza, E | 1 |
| Dehlin, M | 1 |
| Nuki, G | 1 |
| Schlesinger, N | 1 |
| Janssen, M | 1 |
| Stamp, LK | 2 |
| Sivera, F | 1 |
| Reginato, AM | 1 |
| Jacobsson, L | 1 |
| Lioté, F | 1 |
| Ea, HK | 1 |
| Rosenthal, A | 1 |
| Bardin, T | 1 |
| Choi, HK | 1 |
| Hershfield, MS | 1 |
| Czegley, C | 1 |
| Choi, SJ | 1 |
| Dalbeth, N | 1 |
| Zamudio-Cuevas, Y | 1 |
| Fernández-Torres, J | 1 |
| Martínez-Nava, GA | 1 |
| Martínez-Flores, K | 1 |
| López-Reyes, A | 1 |
| Mahon, OR | 1 |
| Dunne, A | 1 |
| Li, H | 1 |
| Ou, G | 1 |
| He, Y | 1 |
| Ren, L | 1 |
| Yang, X | 1 |
| Zeng, M | 1 |
| Anderson, NG | 1 |
| Becce, F | 1 |
| Rajeswari, M | 1 |
| Polson, M | 1 |
| Guyen, O | 1 |
| Viry, A | 1 |
| Choi, C | 1 |
| Kirkbride, TE | 1 |
| Raja, AY | 1 |
| Reuss-Borst, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Allopurinol on Inflammatory Markers and Morphostructural Changes Evidenced by Musculoskeletal Ultrasound in Individuals With Asymptomatic Hyperuricemia. A Proof of Concept[NCT04012294] | Phase 3 | 200 participants (Anticipated) | Interventional | 2019-08-30 | Recruiting | ||
| Novel Complex Radiodiagnostics of Peripherial Arthropathies[NCT05657847] | 500 participants (Anticipated) | Observational | 2022-03-07 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for uric acid and Crystal Arthritis
| Article | Year |
|---|---|
Crystal arthropathies and osteoarthritis-where is the link?
Topics: Calcinosis; Crystal Arthropathies; Gout; Humans; Inflammation; Osteoarthritis; Uric Acid | 2023 |
Clinical implications of synovial fluid specimen handling for crystal associated arthritides: A systematic review.
Topics: Calcium Pyrophosphate; Crystal Arthropathies; Crystallization; Edetic Acid; Gout; Humans; Predictive | 2021 |
Crystalline arthropathy and bone health.
Topics: Bone and Bones; Bone Density; Chondrocalcinosis; Crystal Arthropathies; Fractures, Bone; Gout; Human | 2018 |
Emergent nanotherapies in microcrystal-induced arthritis.
Topics: Animals; Calcium Phosphates; Chitosan; Chondrocalcinosis; Crystal Arthropathies; Diclofenac; Disease | 2018 |
Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets.
Topics: Animals; Arthritis; Biomarkers; Calcium Pyrophosphate; Crystal Arthropathies; Disease Susceptibility | 2018 |
6 other studies available for uric acid and Crystal Arthritis
| Article | Year |
|---|---|
Mechanosensitive TRPV4 is required for crystal-induced inflammation.
Topics: Adult; Animals; Arthralgia; Arthritis; Arthritis, Gouty; Crystal Arthropathies; Gout; Humans; Inflam | 2021 |
The Limitations of Gram-stain Microscopy of Synovial Fluid in Concomitant Septic and Crystal Arthritis.
Topics: Arthritis, Infectious; Bacteria; Bacteriological Techniques; Biomarkers; Calcium Pyrophosphate; Crys | 2018 |
Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout.
Topics: Consensus; Crystal Arthropathies; Delphi Technique; Gout; Humans; Hyperuricemia; Uric Acid | 2019 |
Resveratrol attenuates the MSU crystal-induced inflammatory response through the inhibition of TAK1 activity.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Crystal Arthropathies; Down-Regulation; Extracel | 2019 |
Clinical Utility of Multi-Energy Spectral Photon-Counting Computed Tomography in Crystal Arthritis.
Topics: Calcium Pyrophosphate; Chondrocalcinosis; Crystal Arthropathies; Diagnosis, Differential; Durapatite | 2019 |
[Crystal arthropathies].
Topics: Anti-Inflammatory Agents; Crystal Arthropathies; Cytokines; Humans; Microscopy; Uric Acid | 2019 |