uric acid has been researched along with Critical Illness in 13 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Based on the first serum uric acid level within 24 h of admission to the ICU, patients were divided into groups with or without hyperuricemia, and the incidence of AKI within seven days of ICU admission was compared between the two groups." | 4.31 | Association between hyperuricemia and acute kidney injury in critically ill patients with sepsis. ( Gong, CL; Jiang, YX; Liu, FG; Shi, YL; Tang, Y; Xie, KQ; Yi, Y; Zhou, HW; Zhou, JW, 2023) |
| "Changes in plasma uric acid concentration (UA, mumol/L) in postoperative and critical illness have pathophysiological and clinical relevance and may alter plasma antioxidant capacity." | 3.74 | Biochemical and clinical correlates of hypouricemia in surgical and critically ill patients. ( Ardito, F; Chiarla, C; Giovannini, I; Giuliante, F; Nuzzo, G; Pallavicini, F; Vellone, M, 2007) |
| "Serum total antioxidant status (TAS) and uric acid (UA) levels were measured in 50 patients over 18 hours to represent the initial stage of critical illness." | 3.70 | Measures of total free radical activity in critically ill patients. ( Lowe, D; MacKinnon, KL; Molnar, Z; Shearer, E; Watson, ID, 1999) |
| "The severity of coronavirus disease 2019 (COVID-19) is highly variable between individuals, ranging from asymptomatic infection to critical disease with acute respiratory distress syndrome requiring mechanical ventilation." | 1.62 | Serum uric acid, disease severity and outcomes in COVID-19. ( Belkhir, L; De Greef, J; Dufour, I; Gérard, L; Jadoul, M; Laterre, PF; Morelle, J; Perrot, M; Schmit, G; Werion, A; Wisniewska, A; Wittebole, X; Yombi, JC, 2021) |
| "Uric acid is a major non-enzymatic antioxidant in the blood, and it exerts a protective action on vitamin C." | 1.48 | The Association Between Serum Uric Acid Level and Prognosis in Critically Ill Patients, Uric Acid as a Prognosis Predictor. ( Er, MC; Kucuk, AO; Ozturk, CE; Pehlivanlar-Kucuk, M; Ulger, F, 2018) |
| "TAC, unable to distinguish severe sepsis and septic shock, is unlikely to be a particularly useful outcome measure." | 1.35 | Plasma antioxidant status in septic critically ill patients: a decrease over time. ( Aho, LS; Aube, H; Blettery, B; Doise, JM; Guilland, JC; Quenot, JP; Rochette, L; Vergely, C; Zeller, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, YX | 1 |
| Gong, CL | 1 |
| Tang, Y | 2 |
| Yi, Y | 1 |
| Liu, FG | 1 |
| Zhou, JW | 1 |
| Shi, YL | 1 |
| Zhou, HW | 1 |
| Xie, KQ | 1 |
| Gong, C | 1 |
| Liu, X | 1 |
| Huang, Y | 1 |
| Fang, H | 1 |
| Cheng, Y | 1 |
| Liu, Y | 1 |
| Wang, D | 1 |
| Dufour, I | 1 |
| Werion, A | 1 |
| Belkhir, L | 1 |
| Wisniewska, A | 1 |
| Perrot, M | 1 |
| De Greef, J | 1 |
| Schmit, G | 1 |
| Yombi, JC | 1 |
| Wittebole, X | 1 |
| Laterre, PF | 1 |
| Jadoul, M | 1 |
| Gérard, L | 1 |
| Morelle, J | 1 |
| Ciapetti, M | 1 |
| Mancinelli, P | 1 |
| Cecchi, A | 1 |
| Borrelli, E | 1 |
| Bocci, V | 1 |
| Peris, A | 1 |
| Pehlivanlar-Kucuk, M | 1 |
| Kucuk, AO | 1 |
| Ozturk, CE | 1 |
| Er, MC | 1 |
| Ulger, F | 1 |
| Giovannini, I | 2 |
| Chiarla, C | 2 |
| Giuliante, F | 2 |
| Pallavicini, F | 2 |
| Vellone, M | 2 |
| Ardito, F | 2 |
| Nuzzo, G | 2 |
| Gunaydin, B | 1 |
| Sancak, B | 1 |
| Candan, S | 1 |
| Sariahmetoğlu, M | 1 |
| Ozçağli, G | 1 |
| Tunçtan, B | 1 |
| Cakici, I | 1 |
| Akçabay, M | 1 |
| Moviat, M | 1 |
| Terpstra, AM | 1 |
| Ruitenbeek, W | 1 |
| Kluijtmans, LA | 1 |
| Pickkers, P | 1 |
| van der Hoeven, JG | 1 |
| Doise, JM | 1 |
| Aho, LS | 1 |
| Quenot, JP | 1 |
| Guilland, JC | 1 |
| Zeller, M | 1 |
| Vergely, C | 1 |
| Aube, H | 1 |
| Blettery, B | 1 |
| Rochette, L | 1 |
| MacKinnon, KL | 1 |
| Molnar, Z | 1 |
| Lowe, D | 1 |
| Watson, ID | 1 |
| Shearer, E | 1 |
| Brunet, S | 1 |
| Leblanc, M | 1 |
| Geadah, D | 1 |
| Parent, D | 1 |
| Courteau, S | 1 |
| Cardinal, J | 1 |
| Molinos Normiella, C | 1 |
| Rey Galán, C | 1 |
| Medina Villanueva, A | 1 |
| Concha Torre, A | 1 |
| Menéndez Cuervo, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock[NCT03380507] | Phase 2/Phase 3 | 106 participants (Actual) | Interventional | 2018-03-17 | Terminated (stopped due to The research is no longer funded and terminated due to futility) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for uric acid and Critical Illness
| Article | Year |
|---|---|
Temporal variation of oxidant stress in critically ill patients.
Topics: Adult; Aged; Antioxidants; Critical Illness; Female; Glutathione Peroxidase; Humans; Lipid Peroxidat | 2007 |
12 other studies available for uric acid and Critical Illness
| Article | Year |
|---|---|
Association between hyperuricemia and acute kidney injury in critically ill patients with sepsis.
Topics: Acute Kidney Injury; Adult; China; Critical Illness; Female; Humans; Hyperuricemia; Intensive Care U | 2023 |
[Analysis of prognosis risk factors of critically ill patients after cardiac surgery: a consecutive 5-year retrospective study].
Topics: Critical Illness; Humans; Intensive Care Units; Prognosis; Retrospective Studies; Risk Factors; ROC | 2019 |
Serum uric acid, disease severity and outcomes in COVID-19.
Topics: Aged; Belgium; Cohort Studies; COVID-19; Critical Illness; Humans; Kidney Tubules, Proximal; Male; M | 2021 |
Reduction of non-enzymatic antioxidants in plasma during ECMO-treatment in ARDS by influence A H1N1.
Topics: Antioxidants; Critical Illness; Extracorporeal Membrane Oxygenation; Female; Humans; Influenza A Vir | 2018 |
The Association Between Serum Uric Acid Level and Prognosis in Critically Ill Patients, Uric Acid as a Prognosis Predictor.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Critical Illness; Female; Healt | 2018 |
Serum uric acid, creatinine, and the assessment of antioxidant capacity in critical illness.
Topics: Antioxidants; Creatinine; Critical Illness; Humans; Sepsis; Uric Acid | 2006 |
Biochemical and clinical correlates of hypouricemia in surgical and critically ill patients.
Topics: Aged; Albumins; Antioxidants; Blood Chemical Analysis; Cholestasis; Critical Illness; Female; Humans | 2007 |
Contribution of various metabolites to the "unmeasured" anions in critically ill patients with metabolic acidosis.
Topics: Acid-Base Imbalance; Acidosis; Adult; Aged; Amino Acids; Anions; Critical Illness; Female; Humans; M | 2008 |
Plasma antioxidant status in septic critically ill patients: a decrease over time.
Topics: Adult; Aged; Analysis of Variance; Antioxidants; Ascorbic Acid; Bilirubin; Biomarkers; Chromatograph | 2008 |
Measures of total free radical activity in critically ill patients.
Topics: Adult; Aged; Antioxidants; Critical Illness; Free Radicals; Humans; Intensive Care Units; Middle Age | 1999 |
Diffusive and convective solute clearances during continuous renal replacement therapy at various dialysate and ultrafiltration flow rates.
Topics: Acute Kidney Injury; Adult; Aged; beta 2-Microglobulin; Blood Flow Velocity; Creatinine; Critical Il | 1999 |
[Uric acid as a prognostic marker in critically ill patients].
Topics: Child, Preschool; Critical Illness; Female; Humans; Male; Prognosis; Prospective Studies; Retrospect | 2001 |