uric acid has been researched along with Creutzfeldt-Jakob Syndrome in 2 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid was also shown to inhibit neurotoxicity of a prion protein peptide, production of the abnormal prion protein isoform (PrP(Sc)) by infected cells, and polymerization of recombinant prion protein." | 1.32 | BSE and vCJD cause disturbance to uric acid levels. ( Brown, DR; Green, A; Ironside, JW; Lekishvili, T; Sassoon, J; Thompsett, AR, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S | 1 |
| He, S | 1 |
| Shang, JK | 1 |
| Ma, MM | 1 |
| Xu, CS | 1 |
| Shi, XH | 1 |
| Zhang, JW | 1 |
| Lekishvili, T | 1 |
| Sassoon, J | 1 |
| Thompsett, AR | 1 |
| Green, A | 1 |
| Ironside, JW | 1 |
| Brown, DR | 1 |
2 other studies available for uric acid and Creutzfeldt-Jakob Syndrome
| Article | Year |
|---|---|
Serum uric acid and lipid profiles in sporadic Creutzfeldt-Jakob disease.
Topics: Adult; Aged; Case-Control Studies; Creutzfeldt-Jakob Syndrome; Female; Humans; Lipoproteins, HDL; Li | 2016 |
BSE and vCJD cause disturbance to uric acid levels.
Topics: Animals; Brain; Brain Chemistry; Cattle; Cell Survival; Cells, Cultured; Creutzfeldt-Jakob Syndrome; | 2004 |