uric acid has been researched along with Cognitive Dysfunction in 38 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum uric acid (UA) has been suggested to be correlated with outcomes after stroke." | 9.22 | Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis. ( Jin, X; Ren, Z; Wang, Y; Wen, Q; Yan, X; Zhang, W, 2022) |
| "Serum uric acid (sUA) level may be associated with cognitive impairment/dementia." | 8.93 | Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. ( Dawson, J; Fan, Y; Hewitt, J; Khan, AA; Quinn, TJ, 2016) |
| "Elevated serum uric acid (SUA) is associated with cardiovascular risk factors, which often contribute to dementia and dementia-like morbidity, yet several cross-sectional studies have shown protective associations with cognition, which would be consistent with other work showing benefits of elevated SUA through its antioxidant properties." | 7.96 | Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort. ( Alam, AB; Alonso, A; Power, MC; West, NA; Wu, A, 2020) |
| " Although recent studies have shown that high serum uric acid (UA) levels are associated with cognitive dysfunction and may be a risk factor for PSCI, its impact remains unclear." | 7.96 | The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke. ( Chen, W; Chen, Z; Gao, X; Gu, Q; Ling, Y; Liu, J; Liu, S; Lv, X; Sun, J; Wei, D; Zhang, J, 2020) |
| "This narrative review aims to highlight recent findings on the relation between uric acid level and cognitive decline or dementia." | 7.88 | Uric acid and cognitive decline: a double-edge sword? ( Bardin, T; Latourte, A; Richette, P, 2018) |
| "Objective To explore the possible correlation between uric acid levels and leukoaraiosis (LA)." | 7.85 | The association of uric acid with leukoaraiosis. ( Cai, RW; Chen, YF; Huang, YH; Li, JJ; Li, MM; Lin, YY, 2017) |
| "The association of serum uric acid, cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) and longitudinal cognitive decline was evaluated using the AD Neuroimaging Initiative database." | 7.83 | Does serum uric acid act as a modulator of cerebrospinal fluid Alzheimer's disease biomarker related cognitive decline? ( Ham, JH; Lee, JJ; Lee, PH; Lee, WW; Sohn, YH; Ye, BS, 2016) |
| "The uric acid(UA) level was measured using automatic biochemical analyzer, and cognitive function was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and Stroop color-word test." | 5.91 | Association between uric acid and cognitive dysfunction: A cross-sectional study with newly diagnosed, drug-naïve with bipolar disorder. ( Chen, J; Li, S; Lu, X; Qiu, Y; Tang, H; Teng, Z; Wang, B; Wu, H; Xiang, H; Xu, X; Zhao, Z, 2023) |
| "Cognitive impairment induced by cerebral infarction has become a devastating health problem." | 5.56 | Serum Uric Acid and High-Sensitivity C-Reactive Protein as Predictors of Cognitive Impairment in Patients with Cerebral Infarction. ( Chen, L; Liu, F; Ran, F; Zhang, Y, 2020) |
| "67) and also revealed a dose-response relationship in this subgroup." | 5.43 | Association of cognitive function and serum uric acid: Are cardiovascular diseases a mediator among women? ( Brenner, H; Mons, U; Perna, L; Schöttker, B, 2016) |
| "Serum uric acid (UA) has been suggested to be correlated with outcomes after stroke." | 5.22 | Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis. ( Jin, X; Ren, Z; Wang, Y; Wen, Q; Yan, X; Zhang, W, 2022) |
| "This study conducts a systematic literature review and meta-analysis regarding the potential influence of serum uric acid levels on cerebral small vessel diseases and the cognitive status in the prodromal stages of dementia." | 5.22 | The relationship between uric acid and brain health from observational studies. ( Cardoso, MA; Simó, R; Song, ZH; Tang, X; Zhou, JB, 2022) |
| "Serum uric acid (sUA) level may be associated with cognitive impairment/dementia." | 4.93 | Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. ( Dawson, J; Fan, Y; Hewitt, J; Khan, AA; Quinn, TJ, 2016) |
| "Elevated serum uric acid (SUA) is associated with cardiovascular risk factors, which often contribute to dementia and dementia-like morbidity, yet several cross-sectional studies have shown protective associations with cognition, which would be consistent with other work showing benefits of elevated SUA through its antioxidant properties." | 3.96 | Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort. ( Alam, AB; Alonso, A; Power, MC; West, NA; Wu, A, 2020) |
| " Although recent studies have shown that high serum uric acid (UA) levels are associated with cognitive dysfunction and may be a risk factor for PSCI, its impact remains unclear." | 3.96 | The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke. ( Chen, W; Chen, Z; Gao, X; Gu, Q; Ling, Y; Liu, J; Liu, S; Lv, X; Sun, J; Wei, D; Zhang, J, 2020) |
| "Lower serum urate concentration is associated with worsening motor function; while higher homocysteine concentration is associated with change in motor function and cognitive decline." | 3.91 | Urate and Homocysteine: Predicting Motor and Cognitive Changes in Newly Diagnosed Parkinson's Disease. ( Burn, DJ; Duncan, GW; Johnston, F; Khoo, TK; Lawson, RA; Sleeman, I; Yarnall, AJ, 2019) |
| "This narrative review aims to highlight recent findings on the relation between uric acid level and cognitive decline or dementia." | 3.88 | Uric acid and cognitive decline: a double-edge sword? ( Bardin, T; Latourte, A; Richette, P, 2018) |
| "Objective To explore the possible correlation between uric acid levels and leukoaraiosis (LA)." | 3.85 | The association of uric acid with leukoaraiosis. ( Cai, RW; Chen, YF; Huang, YH; Li, JJ; Li, MM; Lin, YY, 2017) |
| "Uric acid (UA) may not only prevent development of cognitive dysfunction owing to its antioxidant efficacy, but also may worsen cognitive functions by gaining pro-oxidant character." | 3.85 | Uric acid may be protective against cognitive impairment in older adults, but only in those without cardiovascular risk factors. ( Isik, AT; Kaya, D; Soysal, P; Tuven, B; Unutmaz, G, 2017) |
| "The association of serum uric acid, cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) and longitudinal cognitive decline was evaluated using the AD Neuroimaging Initiative database." | 3.83 | Does serum uric acid act as a modulator of cerebrospinal fluid Alzheimer's disease biomarker related cognitive decline? ( Ham, JH; Lee, JJ; Lee, PH; Lee, WW; Sohn, YH; Ye, BS, 2016) |
| " This article examined the association between long-term use of ULT and cognitive decline among community-dwelling older adults with spontaneous memory complaints." | 3.11 | Association between urate-lowering therapies and cognitive decline in community-dwelling older adults. ( Cantet, C; de Souto Barreto, P; Giudici, KV; Molet-Benhamou, L; Rolland, Y, 2022) |
| "Studying the effects of uric acid levels on cognitive function and quantifying the dose-response relationship." | 3.01 | Uric acid levels and risk of cognitive impairment: Dose-response meta-analysis of prospective cohort studies. ( Liu, Q; Peng, M; Si, G; Yang, T, 2023) |
| "It is known that hyperuricemia is recognized as an independent cardiovascular risk factor." | 2.82 | [The role of hyperuricemia in the development of cognitive changes in the elderly.] ( Ariev, AL; Kunitskaya, NA, 2022) |
| "Hyperuricemia has been recognized as an independent cardiovascular risk factor in epidemiological studies." | 2.58 | Uric Acid and Cognitive Function in Older Individuals. ( Meschi, T; Nouvenne, A; Prati, B; Tana, C; Ticinesi, A, 2018) |
| "The uric acid(UA) level was measured using automatic biochemical analyzer, and cognitive function was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and Stroop color-word test." | 1.91 | Association between uric acid and cognitive dysfunction: A cross-sectional study with newly diagnosed, drug-naïve with bipolar disorder. ( Chen, J; Li, S; Lu, X; Qiu, Y; Tang, H; Teng, Z; Wang, B; Wu, H; Xiang, H; Xu, X; Zhao, Z, 2023) |
| "Hyperuricemia has not been found to increase the risk of cognitive impairment in people 55 years and older." | 1.62 | [Association between mild cognitive impairment and serum uric acid levels among people aged 55 and above in 4 provinces of China]. ( Chen, P; Fu, Z; Hu, D; Su, C; Wang, H; Wang, X; Wang, Z; Zhang, B; Zhang, Z, 2021) |
| "Uric acid is a powerful antioxidant." | 1.62 | Detrimental effects of long-term elevated serum uric acid on cognitive function in rats. ( Gu, CW; Jia, H; Li, SJ; Li, TT; Liu, XR; Nie, ZC; Tang, Y; Tian, T; Xu, WD, 2021) |
| "Cognitive impairment induced by cerebral infarction has become a devastating health problem." | 1.56 | Serum Uric Acid and High-Sensitivity C-Reactive Protein as Predictors of Cognitive Impairment in Patients with Cerebral Infarction. ( Chen, L; Liu, F; Ran, F; Zhang, Y, 2020) |
| "Uric acid (UA) has long been implicated as a critical cause of cardiovascular disease." | 1.46 | Uric acid is associated with vascular dementia in Chinese population. ( Cui, R; Liu, Y; Lu, K; Wang, Q; Xu, Y; Zhao, Y, 2017) |
| "67) and also revealed a dose-response relationship in this subgroup." | 1.43 | Association of cognitive function and serum uric acid: Are cardiovascular diseases a mediator among women? ( Brenner, H; Mons, U; Perna, L; Schöttker, B, 2016) |
| "Cognitive deficits are common in Parkinson's disease (PD) and many patients eventually develop dementia; however, its occurrence is unpredictable." | 1.43 | Lower serum uric acid is associated with mild cognitive impairment in early Parkinson's disease: a 4-year follow-up study. ( Amboni, M; Barone, P; Erro, R; Moccia, M; Pellecchia, MT; Picillo, M; Santangelo, G; Savastano, R; Siano, P; Vallelunga, A; Vitale, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 22 (57.89) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, C | 1 |
| Guo, H | 1 |
| Liu, X | 1 |
| Yan, X | 1 |
| Ren, Z | 1 |
| Wen, Q | 1 |
| Jin, X | 1 |
| Wang, Y | 2 |
| Zhang, W | 1 |
| Tang, X | 1 |
| Song, ZH | 1 |
| Cardoso, MA | 1 |
| Zhou, JB | 1 |
| Simó, R | 1 |
| Molet-Benhamou, L | 1 |
| Giudici, KV | 1 |
| de Souto Barreto, P | 1 |
| Cantet, C | 1 |
| Rolland, Y | 1 |
| Li, YM | 1 |
| Yu, Q | 1 |
| Huang, L | 1 |
| Fu, J | 1 |
| Feng, RJ | 1 |
| Chen, Y | 3 |
| Cao, P | 3 |
| Xiao, Z | 3 |
| Ruan, Z | 3 |
| Kunitskaya, NA | 1 |
| Ariev, AL | 1 |
| Li, S | 1 |
| Lu, X | 1 |
| Qiu, Y | 1 |
| Teng, Z | 1 |
| Zhao, Z | 1 |
| Xu, X | 1 |
| Tang, H | 1 |
| Xiang, H | 1 |
| Chen, J | 1 |
| Wang, B | 1 |
| Wu, H | 1 |
| Kawada, T | 1 |
| Khaled, Y | 1 |
| Abdelhamid, AA | 1 |
| Al-Mazroey, H | 1 |
| Almannai, AK | 1 |
| Fetais, S | 1 |
| Al-Srami, AS | 1 |
| Ahmed, S | 1 |
| Al-Hajri, N | 1 |
| Mustafa, A | 1 |
| Chivese, T | 1 |
| Djouhri, L | 1 |
| Tong, XW | 1 |
| Zhang, YT | 1 |
| Li, X | 1 |
| Yu, ZW | 1 |
| Pu, SD | 1 |
| Xu, YX | 1 |
| Shan, YY | 1 |
| Gao, XY | 1 |
| Liu, Q | 1 |
| Peng, M | 1 |
| Yang, T | 1 |
| Si, G | 1 |
| Zhang, J | 2 |
| Tang, L | 1 |
| Hu, J | 1 |
| Xu, Y | 2 |
| Boccardi, V | 1 |
| Carino, S | 1 |
| Marinelli, E | 1 |
| Lapenna, M | 1 |
| Caironi, G | 1 |
| Bianco, AR | 1 |
| Cecchetti, R | 1 |
| Ruggiero, C | 1 |
| Mecocci, P | 1 |
| Kim, HJ | 1 |
| Sohn, IW | 1 |
| Kim, YS | 1 |
| Jun, JB | 1 |
| Alam, AB | 1 |
| Wu, A | 1 |
| Power, MC | 1 |
| West, NA | 1 |
| Alonso, A | 1 |
| Sun, J | 1 |
| Lv, X | 1 |
| Gao, X | 1 |
| Chen, Z | 1 |
| Wei, D | 1 |
| Ling, Y | 1 |
| Gu, Q | 1 |
| Liu, J | 1 |
| Chen, W | 1 |
| Liu, S | 1 |
| Ran, F | 1 |
| Liu, F | 1 |
| Zhang, Y | 2 |
| Chen, L | 1 |
| Su, C | 1 |
| Hu, D | 1 |
| Wang, X | 1 |
| Chen, P | 1 |
| Fu, Z | 1 |
| Zhang, Z | 1 |
| Wang, Z | 1 |
| Wang, H | 1 |
| Zhang, B | 1 |
| Tian, T | 1 |
| Liu, XR | 1 |
| Li, TT | 1 |
| Nie, ZC | 1 |
| Li, SJ | 1 |
| Tang, Y | 1 |
| Gu, CW | 1 |
| Xu, WD | 1 |
| Jia, H | 1 |
| Qiao, M | 1 |
| Chen, C | 1 |
| Liang, Y | 1 |
| Luo, Y | 1 |
| Wu, W | 1 |
| Lee, YG | 1 |
| Park, M | 1 |
| Jeong, SH | 1 |
| Kang, SW | 1 |
| Baik, K | 1 |
| Jung, JH | 1 |
| Lee, PH | 2 |
| Sohn, YH | 2 |
| Ye, BS | 2 |
| Wang, T | 1 |
| Sun, ZW | 1 |
| Shao, LQ | 1 |
| Xu, XB | 1 |
| Liu, Y | 2 |
| Qin, M | 1 |
| Weng, X | 1 |
| Zhang, YX | 1 |
| Wang, F | 1 |
| Zhao, M | 1 |
| Han, Z | 1 |
| Li, D | 1 |
| Zhang, S | 1 |
| Kong, X | 1 |
| Sun, N | 1 |
| Zhang, Q | 1 |
| Lei, P | 1 |
| Liu, M | 1 |
| Wang, J | 2 |
| Zeng, J | 1 |
| He, Y | 1 |
| Latourte, A | 1 |
| Bardin, T | 1 |
| Richette, P | 1 |
| Tana, C | 1 |
| Ticinesi, A | 1 |
| Prati, B | 1 |
| Nouvenne, A | 1 |
| Meschi, T | 1 |
| Sleeman, I | 1 |
| Lawson, RA | 1 |
| Yarnall, AJ | 1 |
| Duncan, GW | 1 |
| Johnston, F | 1 |
| Khoo, TK | 1 |
| Burn, DJ | 1 |
| Huang, R | 1 |
| Tian, S | 1 |
| Han, J | 1 |
| Lin, H | 1 |
| Guo, D | 1 |
| An, K | 1 |
| Wang, S | 1 |
| Cervellati, C | 1 |
| Romani, A | 1 |
| Seripa, D | 1 |
| Cremonini, E | 1 |
| Bosi, C | 1 |
| Magon, S | 1 |
| Passaro, A | 1 |
| Bergamini, CM | 1 |
| Pilotto, A | 1 |
| Zuliani, G | 1 |
| Khan, AA | 1 |
| Quinn, TJ | 1 |
| Hewitt, J | 1 |
| Fan, Y | 1 |
| Dawson, J | 1 |
| Lee, WW | 1 |
| Ham, JH | 1 |
| Lee, JJ | 1 |
| Perna, L | 1 |
| Mons, U | 1 |
| Schöttker, B | 1 |
| Brenner, H | 1 |
| Desideri, G | 1 |
| Gentile, R | 1 |
| Antonosante, A | 1 |
| Benedetti, E | 1 |
| Grassi, D | 1 |
| Cristiano, L | 1 |
| Manocchio, A | 1 |
| Selli, S | 1 |
| Ippoliti, R | 1 |
| Ferri, C | 1 |
| Borghi, C | 1 |
| Giordano, A | 1 |
| Cimini, A | 1 |
| Pellecchia, MT | 1 |
| Savastano, R | 1 |
| Moccia, M | 1 |
| Picillo, M | 1 |
| Siano, P | 1 |
| Erro, R | 1 |
| Vallelunga, A | 1 |
| Amboni, M | 1 |
| Vitale, C | 1 |
| Santangelo, G | 1 |
| Barone, P | 1 |
| Li, JJ | 1 |
| Huang, YH | 1 |
| Lin, YY | 1 |
| Li, MM | 1 |
| Chen, YF | 1 |
| Cai, RW | 1 |
| Tuven, B | 1 |
| Soysal, P | 1 |
| Unutmaz, G | 1 |
| Kaya, D | 1 |
| Isik, AT | 1 |
| Wang, Q | 1 |
| Cui, R | 1 |
| Lu, K | 1 |
| Zhao, Y | 1 |
7 reviews available for uric acid and Cognitive Dysfunction
| Article | Year |
|---|---|
Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis.
Topics: Cognitive Dysfunction; Humans; Ischemic Stroke; Prospective Studies; Stroke; Uric Acid | 2022 |
The relationship between uric acid and brain health from observational studies.
Topics: Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Hum | 2022 |
[The role of hyperuricemia in the development of cognitive changes in the elderly.]
Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Dementia; Dementia, Vascular; Humans; Hyp | 2022 |
Uric acid levels and risk of cognitive impairment: Dose-response meta-analysis of prospective cohort studies.
Topics: Cognition; Cognitive Dysfunction; Humans; Male; Prospective Studies; Risk Factors; Uric Acid | 2023 |
The Influence of Serum Uric Acid Level on Alzheimer's Disease: A Narrative Review.
Topics: Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Humans; Risk Factors; Uric Acid | 2021 |
Uric Acid and Cognitive Function in Older Individuals.
Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Dementia; Dementia, Vascular; Disease Pro | 2018 |
Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis.
Topics: Aging; Cognition; Cognitive Dysfunction; Dementia; Disease Progression; Humans; Neuropsychological T | 2016 |
1 trial available for uric acid and Cognitive Dysfunction
| Article | Year |
|---|---|
Association between urate-lowering therapies and cognitive decline in community-dwelling older adults.
Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Humans; Independent Living; Uric Acid | 2022 |
30 other studies available for uric acid and Cognitive Dysfunction
| Article | Year |
|---|---|
High uric acid induced hippocampal mitochondrial dysfunction and cognitive impairment involving intramitochondrial NF-κB inhibitor α/nuclear factor-κB pathway.
Topics: Animals; Cognitive Dysfunction; Hippocampus; Mice; Mitochondria; NF-kappa B; NF-KappaB Inhibitor alp | 2022 |
[Correlations Between Gut Microbiota Changes and Cognitive Function in Patients with Post-Stroke Cognitive Impairment in the Early Stage].
Topics: Bacteria; Bifidobacterium; Biomarkers; Clostridiales; Cognition; Cognitive Dysfunction; Cross-Sectio | 2022 |
m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-κB pathway mediated NLRP3-ASC-Caspase1 inflammasome.
Topics: Adaptor Proteins, Signal Transducing; Animals; CARD Signaling Adaptor Proteins; Caspase 1; Cells, Cu | 2022 |
m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-κB pathway mediated NLRP3-ASC-Caspase1 inflammasome.
Topics: Adaptor Proteins, Signal Transducing; Animals; CARD Signaling Adaptor Proteins; Caspase 1; Cells, Cu | 2022 |
m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-κB pathway mediated NLRP3-ASC-Caspase1 inflammasome.
Topics: Adaptor Proteins, Signal Transducing; Animals; CARD Signaling Adaptor Proteins; Caspase 1; Cells, Cu | 2022 |
m(6)A methyltransferase METTL3 relieves cognitive impairment of hyperuricemia mice via inactivating MyD88/NF-κB pathway mediated NLRP3-ASC-Caspase1 inflammasome.
Topics: Adaptor Proteins, Signal Transducing; Animals; CARD Signaling Adaptor Proteins; Caspase 1; Cells, Cu | 2022 |
Association between uric acid and cognitive dysfunction: A cross-sectional study with newly diagnosed, drug-naïve with bipolar disorder.
Topics: Bipolar Disorder; Cognition Disorders; Cognitive Dysfunction; Cross-Sectional Studies; Female; Human | 2023 |
Serum uric acid and dementia subtype.
Topics: Cognitive Dysfunction; Dementia; Humans; Uric Acid | 2023 |
Higher serum uric acid is associated with poorer cognitive performance in healthy middle-aged people: a cross-sectional study.
Topics: Adult; Aged; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Male; Middle | 2023 |
Uric acid index is a risk for mild cognitive impairment in type 2 diabetes.
Topics: Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans | 2023 |
Uric acid is associated with cognitive impairment in the elderly patients receiving maintenance hemodialysis-A two-center study.
Topics: Aged; Blood Pressure; Cognition; Cognitive Dysfunction; Female; Humans; Male; Middle Aged; Neuropsyc | 2020 |
Uric acid and late-onset Alzheimer's disease: results from the ReGAl 2.0 project.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Female; Humans; Italy | 2021 |
The Different Relationship between Homocysteine and Uric Acid Levels with Respect to the MTHFR C677T Polymorphism According to Gender in Patients with Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Biomarkers; Cerebrovascular Disorders; Cognitive Dysfunction; Female; Genet | 2020 |
Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort.
Topics: Aged; Atherosclerosis; Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Humans; Middle Aged | 2020 |
The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke.
Topics: Aged; Biomarkers; Cognitive Dysfunction; Female; Humans; Ischemic Stroke; Male; Middle Aged; Risk Fa | 2020 |
Serum Uric Acid and High-Sensitivity C-Reactive Protein as Predictors of Cognitive Impairment in Patients with Cerebral Infarction.
Topics: Aged; Biomarkers; C-Reactive Protein; Cerebral Infarction; Cognition; Cognitive Dysfunction; Female; | 2020 |
[Association between mild cognitive impairment and serum uric acid levels among people aged 55 and above in 4 provinces of China].
Topics: China; Cognitive Dysfunction; Cohort Studies; Humans; Hyperuricemia; Middle Aged; Risk Factors; Uric | 2021 |
Detrimental effects of long-term elevated serum uric acid on cognitive function in rats.
Topics: Animals; Biomarkers; Cognition; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Disease Su | 2021 |
Effects of baseline serum uric acid and apolipoprotein E4 on longitudinal cognition and cerebral metabolism.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Apolipoprotein E4; Brain; Cognition; Cogni | 2021 |
Diagnostic Values of Serum Levels of Homocysteine and Uric Acid for Predicting Vascular Mild Cognitive Impairment in Patients with Cerebral Small Vessel Disease.
Topics: Aged; Case-Control Studies; Cerebral Small Vessel Diseases; Cholesterol; Cognitive Dysfunction; Fema | 2017 |
Hyperuricemia as a Protective Factor for Mild Cognitive Impairment in Non-Obese Elderly.
Topics: Aged; C-Reactive Protein; Case-Control Studies; Cognitive Dysfunction; Female; Humans; Hyperuricemia | 2017 |
Relationship between serum uric acid level and mild cognitive impairment in Chinese community elderly.
Topics: Aged; Asian People; China; Cognitive Dysfunction; Cross-Sectional Studies; Female; Humans; Hyperuric | 2017 |
Uric acid and cognitive decline: a double-edge sword?
Topics: Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Gout; Humans; Hyperuricemia; Oxidative Str | 2018 |
Urate and Homocysteine: Predicting Motor and Cognitive Changes in Newly Diagnosed Parkinson's Disease.
Topics: Aged; Case-Control Studies; Cognitive Dysfunction; Disease Progression; Female; Follow-Up Studies; H | 2019 |
U-Shaped Association Between Serum Uric Acid Levels and Cognitive Functions in Patients with Type 2 Diabetes: A Cross-Sectional Study.
Topics: Aged; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; | 2019 |
Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.
Topics: Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cogni | 2014 |
Does serum uric acid act as a modulator of cerebrospinal fluid Alzheimer's disease biomarker related cognitive decline?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition Disorders; Cognitive Dysfunction; | 2016 |
Association of cognitive function and serum uric acid: Are cardiovascular diseases a mediator among women?
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cognitive Dysfunction; Cohort Studies; Cross-Secti | 2016 |
Uric Acid Amplifies Aβ Amyloid Effects Involved in the Cognitive Dysfunction/Dementia: Evidences From an Experimental Model In Vitro.
Topics: Aldehydes; Amyloid; Amyloid beta-Peptides; Blotting, Western; Brain-Derived Neurotrophic Factor; Cel | 2017 |
Lower serum uric acid is associated with mild cognitive impairment in early Parkinson's disease: a 4-year follow-up study.
Topics: Aged; Cognitive Dysfunction; Female; Humans; Italy; Logistic Models; Longitudinal Studies; Magnetic | 2016 |
The association of uric acid with leukoaraiosis.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Asian People; Cognitive Dysfunction; Cross-Sectional Stud | 2017 |
Uric acid may be protective against cognitive impairment in older adults, but only in those without cardiovascular risk factors.
Topics: Aged; Aged, 80 and over; Cognitive Dysfunction; Dementia; Female; Heart Failure; Humans; Hypertensio | 2017 |
Uric acid is associated with vascular dementia in Chinese population.
Topics: Aged; China; Cognitive Dysfunction; Dementia, Vascular; Female; Humans; Male; Middle Aged; Protectiv | 2017 |