Page last updated: 2024-10-20

uric acid and Cirrhosis

uric acid has been researched along with Cirrhosis in 61 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Among patients with immunoglobulin A nephropathy, the higher levels of fibrinogen and uric acid may mean a higher score of tubular atrophy/interstitial fibrosis, which suggests the renal biopsy should be performed for these patients as early as possible to defined pathological classification, even though there is no obvious abnormal change in the test of renal function."8.12A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score. ( Hu, S; Lou, Z; Tu, M, 2022)
"The current work explored the influences of nifuroxazide, an in vivo inhibitor of signal transducer and activator of transcription-3 (STAT-3) activation, on tubulointerstitial fibrosis in rats with obstructive nephropathy using unilateral ureteral obstruction (UUO) model."8.02Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation. ( Hassan, NME; Said, E; Shehatou, GSG, 2021)
" The effects of API on renal function, inflammation, fibrosis, and uric acid (UA) metabolism in mice with HN were evaluated."8.02Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway. ( Cao, Y; Chen, Y; Huang, Q; Jiang, Y; Li, L; Li, Y; Luo, J; Pang, J; Wu, T; Zhang, L; Zhao, Z; Zhou, P, 2021)
" This study investigated the effects of two neutral CB1 receptor antagonists, AM6545 and AM4113, on nephropathy associated with metabolic syndrome (MetS)."8.02Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. ( Aldawsari, HM; Binmahfouz, L; Eid, BG; El-Aziz, GA; El-Bassossy, HM; Hanafy, A; Hasan, A; Makriyannis, A; Neamatallah, T; Vemuri, K, 2021)
" The effects of phloretin on renal function, fibrosis, oxidative stress, inflammation, and UA metabolism in HUA mice were evaluated."7.96Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption. ( Chen, Y; Cheng, J; Cui, D; Li, L; Liu, J; Liu, S; Lu, Y; Mao, R; Tang, M; Wang, C; Yuan, Y; Zhao, M, 2020)
"Several experimental studies implicate uric acid in renal injury and fibrosis."7.88Association between post-transplant uric acid level and renal allograft fibrosis: Analysis using Banff pathologic scores from renal biopsies. ( Choi, HY; Huh, KH; Jeong, HJ; Kim, BS; Kim, DG; Kim, MS; Kim, YS; Lim, BJ, 2018)
" Previous studies using uric acid-lowering drugs in normouricemic animals are not suitable to answer the effect of hyperuricemia on ventricular remodeling after myocardial infarction."7.77Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia. ( Chen, CC; Hsu, YJ; Lee, TM, 2011)
"Triclosan (TCS) is a ubiquitous antimicrobial used in daily consumer products."5.91Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders. ( Cai, Z; Cao, G; Chen, D; Chen, Y; Deng, C; Huang, W; Wang, T, 2023)
"Fibrosis is the culprit in the electrical derangement of the myocytes."5.91Uric acid significantly correlates with the presence of low-voltage areas at the endocardial mapping in patients with non-valvular atrial fibrillation. ( Baroni, M; Carbonaro, M; Ciampi, CM; Fortuna, M; Giannattasio, C; Gigli, L; Leidi, F; Maloberti, A; Mazzone, P; Paolucci, M; Testoni, A; Vargiu, S; Varrenti, M, 2023)
"Chloroquine (CQ) is an anti-inflammatory and disease-modifying anti-rheumatic drug (DMARD) utilized in treating autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus."5.91Chloroquine inhibits NLRP3 inflammasomes activation and alleviates renal fibrosis in mouse model of hyperuricemic nephropathy with aggravation by a high-fat-diet. ( Cui, J; Hong, P; Li, Z; Lin, J; Nie, K; Wan, J; Wu, X; Zhang, X, 2023)
"Calcitriol treatment attenuated the injury with reducing uric acid and creatinine levels, as well as tubular injury."5.62Calcitriol Treatment Attenuates Uric Acid-Induced Kidney Injury via Super Oxide Dismutase-1 (SOD-1) Upregulation and Fibrosis Reduction ( Arefian, N; Juffrie, M; Perdana Putri, RG; Ratna Sari, DC; Romi, MM; Wahyu Setyaningsih, WA, 2021)
"Esculetin is a candidate urate-lowering drug with renoprotective activity and the ability to inhibit XO, promote excretion of UA, protect oxidative stress injury, and reduce renal fibrosis."5.56Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis. ( Huang, B; Kong, W; Meng, J; Wang, L; Wang, Y; Xie, Z; Yang, B; Zhang, T; Zhou, H, 2020)
"Preventing and treating renal fibrosis was an optimal treatment for hyperuricemia-induced kidney diseases."5.51Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy. ( Feng, Y; Fu, P; Guo, F; Li, L; Liu, J; Ma, L; Pan, J; Shi, M, 2019)
"Renal fibrosis is a complication of kidney injury and associated with increased risk of morbidity and mortality."5.48Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats. ( Begum, J; Kumar, D; Kumar, P; Lingaraju, MC; Mathesh, K; Sharma, A; Singh, TU; Thakur, R, 2018)
"Hyperuricemia is associated with the development of chronic kidney disease."5.46Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats. ( Beibei, T; Huijuan, W; Jianchun, M; Rui, S; Xiaoxu, C; Xinghui, L, 2017)
" The indirect effects involve a reduction in insulin levels and resistance, uric acid concentration, body weight, and blood pressure."4.98The Anticipated Renoprotective Effects of Sodium-glucose Cotransporter 2 Inhibitors. ( Ito, M; Tanaka, T, 2018)
"Uric acid has promoted renal fibrosis and inflammation in experimental studies, but some studies have shown nephroprotective effects due to alleviated oxidative stress."4.31Moderate hyperuricaemia ameliorated kidney damage in a low-renin model of experimental renal insufficiency. ( Eräranta, A; Honkanen, T; Kurra, V; Lakkisto, P; Mustonen, J; Myllymäki, J; Paavonen, T; Pörsti, I; Riutta, A; Tikkanen, I, 2023)
"Excessive serum uric acid (SUA) causes hyperuricemic nephropathy (HN), characterized by inflammatory infiltration and tubulointerstitial fibrosis."4.12Fufang Zhenzhu Tiaozhi capsule ameliorates hyperuricemic nephropathy by inhibition of PI3K/AKT/NF-κB pathway. ( Chen, Z; Guan, J; Guo, J; Hu, XG; Lan, T; Li, MH; Mo, JX; Wu, KR, 2022)
"Among patients with immunoglobulin A nephropathy, the higher levels of fibrinogen and uric acid may mean a higher score of tubular atrophy/interstitial fibrosis, which suggests the renal biopsy should be performed for these patients as early as possible to defined pathological classification, even though there is no obvious abnormal change in the test of renal function."4.12A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score. ( Hu, S; Lou, Z; Tu, M, 2022)
"Treatment with STAT3 inhibitor S3I-201 improved renal dysfunction, reduced serum uric acid level, and delayed the progression of kidney fibrosis."4.02Pharmacologic inhibiting STAT3 delays the progression of kidney fibrosis in hyperuricemia-induced chronic kidney disease. ( Fu, P; Guo, F; Ma, L; Pan, J; Shi, M, 2021)
"High levels of serum uric acid is closely associated with atrial fibrillation (AF); nonetheless, the detailed mechanisms remain unknown."4.02Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications. ( Li, Y; Liang, D; Liang, Z; Liu, H; Liu, Y; Su, M; Sun, L; Wang, D; Wei, Y; Yin, S; Zhang, G; Zhang, S; Zhao, J, 2021)
" This study investigated the effects of two neutral CB1 receptor antagonists, AM6545 and AM4113, on nephropathy associated with metabolic syndrome (MetS)."4.02Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. ( Aldawsari, HM; Binmahfouz, L; Eid, BG; El-Aziz, GA; El-Bassossy, HM; Hanafy, A; Hasan, A; Makriyannis, A; Neamatallah, T; Vemuri, K, 2021)
"The current work explored the influences of nifuroxazide, an in vivo inhibitor of signal transducer and activator of transcription-3 (STAT-3) activation, on tubulointerstitial fibrosis in rats with obstructive nephropathy using unilateral ureteral obstruction (UUO) model."4.02Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation. ( Hassan, NME; Said, E; Shehatou, GSG, 2021)
"Fisetin lowered uricemia, suppressed renal inflammatory response, and improved kidney fibrosis to protect against hyperuricemic nephropathy via modulation of STAT3 and TGF-β signaling pathways."4.02Natural flavonol fisetin attenuated hyperuricemic nephropathy via inhibiting IL-6/JAK2/STAT3 and TGF-β/SMAD3 signaling. ( Fu, P; Guo, F; Ma, L; Ren, Q; Tao, S; Wang, B; Yang, L, 2021)
" The effects of API on renal function, inflammation, fibrosis, and uric acid (UA) metabolism in mice with HN were evaluated."4.02Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway. ( Cao, Y; Chen, Y; Huang, Q; Jiang, Y; Li, L; Li, Y; Luo, J; Pang, J; Wu, T; Zhang, L; Zhao, Z; Zhou, P, 2021)
" The present study assessed the ability of taurine (TAU) to alleviate or prevent AMK-induced nephrotoxicity if co-administrated with AMK focusing on inflammation, apoptosis, and fibrosis."4.02The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation. ( Azmy, A; El-Amir, A; Madbouly, N; Salama, A, 2021)
" The effects of phloretin on renal function, fibrosis, oxidative stress, inflammation, and UA metabolism in HUA mice were evaluated."3.96Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption. ( Chen, Y; Cheng, J; Cui, D; Li, L; Liu, J; Liu, S; Lu, Y; Mao, R; Tang, M; Wang, C; Yuan, Y; Zhao, M, 2020)
"Although the clinical implication of hyperuricemia in chronic kidney disease has been an issue of active debate, recent data suggested a causative role of uric acid (UA) in the development of renal disease."3.88Hyperuricemia and Progression of Chronic Kidney Disease: Role of Phenotype Transition of Renal Tubular and Endothelial Cells. ( Kang, DH, 2018)
"Several experimental studies implicate uric acid in renal injury and fibrosis."3.88Association between post-transplant uric acid level and renal allograft fibrosis: Analysis using Banff pathologic scores from renal biopsies. ( Choi, HY; Huh, KH; Jeong, HJ; Kim, BS; Kim, DG; Kim, MS; Kim, YS; Lim, BJ, 2018)
"Uric acid (UA) has been associated with renal fibrosis and progression of chronic kidney disease."3.85Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney. ( De Paul, AL; Latini, A; Mukdsi, JH; Remor, A; Romero, CA; Torres, AI, 2017)
" The effect of preventing hyperuricemia was determined by concomitant treatment with a xanthine oxidase inhibitor, allopurinol (CsAALP), or with a uricosuric, benzbromarone (CsABENZ), in drinking water."3.78Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. ( Johnson, RJ; Mazali, FC; Mazzali, M, 2012)
" Blood urea nitrogen (BUN), serum creatinine (Scr), uric acid (UA) and proteinuria were evaluated."3.78Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model. ( He, J; Pei, X; Sun, S; Wang, C; Wang, Y; Wu, J; Yu, M; Zhao, W; Zhu, B, 2012)
" Previous studies using uric acid-lowering drugs in normouricemic animals are not suitable to answer the effect of hyperuricemia on ventricular remodeling after myocardial infarction."3.77Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia. ( Chen, CC; Hsu, YJ; Lee, TM, 2011)
" This has led to the hypothesis that uric acid may contribute to renal fibrosis and progressive renal disease."3.76Uric acid increases fibronectin synthesis through upregulation of lysyl oxidase expression in rat renal tubular epithelial cells. ( Junwei, Y; Lei, J; Li, F; Mingxia, X; Ping, W; Ruoyun, T; Weichun, H; Xiaohua, W; Yang, Z, 2010)
"Uric acid crystal was found in four patients pleural effusion and stones in two patients' spittle which were consist of monosodium urate (MSU)."3.70[Pleural effusion of gout]. ( Han, Y; Liu, L; Zhang, K, 2000)
"Chloroquine (CQ) is an anti-inflammatory and disease-modifying anti-rheumatic drug (DMARD) utilized in treating autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus."1.91Chloroquine inhibits NLRP3 inflammasomes activation and alleviates renal fibrosis in mouse model of hyperuricemic nephropathy with aggravation by a high-fat-diet. ( Cui, J; Hong, P; Li, Z; Lin, J; Nie, K; Wan, J; Wu, X; Zhang, X, 2023)
"Fibrosis is the culprit in the electrical derangement of the myocytes."1.91Uric acid significantly correlates with the presence of low-voltage areas at the endocardial mapping in patients with non-valvular atrial fibrillation. ( Baroni, M; Carbonaro, M; Ciampi, CM; Fortuna, M; Giannattasio, C; Gigli, L; Leidi, F; Maloberti, A; Mazzone, P; Paolucci, M; Testoni, A; Vargiu, S; Varrenti, M, 2023)
"Triclosan (TCS) is a ubiquitous antimicrobial used in daily consumer products."1.91Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders. ( Cai, Z; Cao, G; Chen, D; Chen, Y; Deng, C; Huang, W; Wang, T, 2023)
"Hyperuricemia is a critical threat to human health, and conventional medical treatment only aims to treat acute gouty arthritis."1.72Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis. ( Chen, X; Lu, Y; Lu, Z; Meng, F; Pang, X; Zhang, L; Zhao, H; Zhou, L, 2022)
"Calcitriol treatment attenuated the injury with reducing uric acid and creatinine levels, as well as tubular injury."1.62Calcitriol Treatment Attenuates Uric Acid-Induced Kidney Injury via Super Oxide Dismutase-1 (SOD-1) Upregulation and Fibrosis Reduction ( Arefian, N; Juffrie, M; Perdana Putri, RG; Ratna Sari, DC; Romi, MM; Wahyu Setyaningsih, WA, 2021)
"Esculetin is a candidate urate-lowering drug with renoprotective activity and the ability to inhibit XO, promote excretion of UA, protect oxidative stress injury, and reduce renal fibrosis."1.56Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis. ( Huang, B; Kong, W; Meng, J; Wang, L; Wang, Y; Xie, Z; Yang, B; Zhang, T; Zhou, H, 2020)
"Hyperuricemia has been identified as an independent risk factor for chronic kidney disease (CKD) and is associated with the progression of kidney diseases."1.51Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia. ( Bao, W; Fang, L; Gu, H; Lin, T; Liu, N; Lu, J; Ma, S; Qiu, A; Shi, Y; Tao, M; Wang, Y; Xu, L; Zhuang, S, 2019)
"Preventing and treating renal fibrosis was an optimal treatment for hyperuricemia-induced kidney diseases."1.51Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy. ( Feng, Y; Fu, P; Guo, F; Li, L; Liu, J; Ma, L; Pan, J; Shi, M, 2019)
"Renal fibrosis is a complication of kidney injury and associated with increased risk of morbidity and mortality."1.48Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats. ( Begum, J; Kumar, D; Kumar, P; Lingaraju, MC; Mathesh, K; Sharma, A; Singh, TU; Thakur, R, 2018)
"Hyperuricemia is associated with the development of chronic kidney disease."1.46Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats. ( Beibei, T; Huijuan, W; Jianchun, M; Rui, S; Xiaoxu, C; Xinghui, L, 2017)
"Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome."1.46Soluble Uric Acid Activates the NLRP3 Inflammasome. ( Barbuto, JA; Braga, TT; Branco, P; Camara, NO; Castoldi, A; Correa-Costa, M; Davanso, MR; Forni, MF; Franklin, BS; Hiyane, MI; Kowaltowski, AJ; Latz, E; Ramos, RN, 2017)
"Hyperuricemia is an independent risk factor for CKD and contributes to kidney fibrosis."1.42EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy. ( Bao, W; Cheng, SB; Chin, YE; Liu, N; Qiu, A; Shi, Y; Wang, L; Xiong, C; Xu, L; Yan, H; Yang, T; Zhuang, S, 2015)
"A cause for the tumoral calcinosis lesions in these turtles could not be determined; however, based on previous reports in this species, a species-specific predilection, in conjunction with unknown environmental factors, is suspected."1.39Tumoral calcinosis form of hydroxyapatite deposition disease in related red-bellied short-necked turtles, Emydura subglobosa. ( Bicknese, EJ; Burns, RE; Shiraki, R; Stalis, IH; Westropp, JL, 2013)
" The effects of casein or soya protein combined with palm or safflower-seed oil on various serum parameters and renal histology were investigated on hyperuricaemic rats."1.36Relative efficacy of casein or soya protein combined with palm or safflower-seed oil on hyperuricaemia in rats. ( Chiou, HY; Lai, SH; Lo, HC; Wang, YH; Yang, Y, 2010)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (3.28)18.2507
2000's3 (4.92)29.6817
2010's28 (45.90)24.3611
2020's28 (45.90)2.80

Authors

AuthorsStudies
Pan, J2
Shi, M2
Guo, F3
Ma, L4
Fu, P3
Romi, MM1
Arefian, N1
Wahyu Setyaningsih, WA1
Perdana Putri, RG1
Juffrie, M1
Ratna Sari, DC1
Huang, H1
Ding, R1
Chen, Z2
Yi, Z1
Wang, H1
Lv, Y1
Bao, E1
Tu, M1
Hu, S1
Lou, Z1
Wei, H1
Chen, L1
Li, Q1
Liang, X1
Wang, K1
Zhang, Y5
Li, Y3
Liu, Y3
Xu, G1
Chen, JS1
Wang, MX1
Wang, MM1
Zhang, YK1
Guo, X1
Chen, YY1
Zhang, MQ1
Sun, JY1
Liu, YF1
Liu, C1
Zhao, H1
Chen, X1
Zhang, L2
Meng, F1
Zhou, L1
Pang, X1
Lu, Z1
Lu, Y4
Zhou, X1
Zhang, B1
Zhao, X1
Lin, Y1
Zhuang, Y1
Guo, J2
Wang, S2
Li, MH1
Guan, J1
Mo, JX1
Wu, KR1
Hu, XG1
Lan, T1
Yang, C1
Su, HY1
An, N1
Wu, HL1
Guo, XY1
Li, ZH1
Chen, XC1
Zhu, SP1
Wu, D1
Li, HY1
Pan, QJ1
Liang, D2
Liu, HF1
Huang, W1
Cao, G1
Deng, C2
Chen, Y4
Wang, T1
Chen, D1
Cai, Z1
Kurra, V1
Eräranta, A1
Paavonen, T1
Honkanen, T1
Myllymäki, J1
Riutta, A1
Tikkanen, I1
Lakkisto, P1
Mustonen, J1
Pörsti, I1
Baroni, M1
Fortuna, M1
Maloberti, A1
Leidi, F1
Ciampi, CM1
Carbonaro, M1
Testoni, A1
Vargiu, S1
Varrenti, M1
Paolucci, M1
Gigli, L1
Giannattasio, C1
Mazzone, P1
Cui, J1
Hong, P1
Li, Z1
Lin, J1
Wu, X1
Nie, K1
Zhang, X1
Wan, J1
Sun, L2
Liu, Q1
Xue, M1
Yan, H2
Qiu, X1
Tian, Y1
Zhang, H2
Liang, H1
Lu, M1
Yin, J1
Xu, T1
Dai, X1
Liu, T1
Shi, H1
Mo, F1
Sukhorukov, V1
Orekhov, AN1
Gao, S1
Wang, L3
Zhang, D1
Cui, D1
Liu, S1
Tang, M1
Zhao, M1
Mao, R1
Wang, C2
Yuan, Y2
Li, L4
Cheng, J1
Liu, J3
Balakumar, P1
Alqahtani, A1
Khan, NA1
Mahadevan, N1
Dhanaraj, SA1
Wang, Y3
Kong, W1
Zhang, T1
Huang, B1
Meng, J1
Yang, B1
Xie, Z1
Zhou, H1
Wang, D1
Zhang, G1
Liang, Z1
Zhao, J1
Yin, S1
Su, M1
Zhang, S2
Wei, Y1
Liu, H1
Eid, BG1
Neamatallah, T1
Hanafy, A1
El-Bassossy, HM1
Binmahfouz, L1
Aldawsari, HM1
Hasan, A1
El-Aziz, GA1
Vemuri, K1
Makriyannis, A1
Hassan, NME1
Said, E1
Shehatou, GSG1
Ren, Q1
Tao, S1
Wang, B1
Yang, L1
Zhao, Z1
Luo, J1
Jiang, Y1
Huang, Q1
Cao, Y1
Zhou, P1
Wu, T1
Pang, J1
Nakagawa, T1
Sanchez-Lozada, LG1
Andres-Hernando, A1
Kojima, H1
Kasahara, M1
Rodriguez-Iturbe, B1
Bjornstad, P1
Lanaspa, MA1
Johnson, RJ3
Madbouly, N1
Azmy, A1
Salama, A1
El-Amir, A1
Cheng, D1
An, X1
Liao, G1
Zhong, L1
Du, P1
Chen, M1
Zhu, C1
Romero, CA1
Remor, A1
Latini, A1
De Paul, AL1
Torres, AI1
Mukdsi, JH1
Huijuan, W1
Xiaoxu, C1
Rui, S1
Xinghui, L1
Beibei, T1
Jianchun, M1
Kang, DH2
Ito, M1
Tanaka, T2
Thakur, R1
Sharma, A1
Lingaraju, MC1
Begum, J1
Kumar, D2
Mathesh, K1
Kumar, P1
Singh, TU1
Park, SK1
Rosenthal, TR1
Williams, JS1
Shelton, JM1
Takahashi, M1
Bobulescu, IA1
Kim, DG1
Kim, BS1
Choi, HY1
Lim, BJ1
Huh, KH1
Kim, MS1
Jeong, HJ1
Kim, YS1
Feng, Y1
Shi, Y2
Xu, L2
Tao, M1
Fang, L1
Lu, J1
Gu, H1
Ma, S1
Lin, T1
Bao, W2
Qiu, A2
Zhuang, S2
Liu, N2
Song, LL1
Zhang, XR1
Song, YN1
Dai, HZ1
Burns, RE1
Bicknese, EJ1
Westropp, JL1
Shiraki, R1
Stalis, IH1
Neuschwander-Tetri, BA1
Zalewska, A1
Knaś, M1
Gińdzieńska-Sieśkiewicz, E1
Waszkiewicz, N1
Klimiuk, A1
Litwin, K1
Sierakowski, S1
Waszkiel, D1
Kim, IY1
Lee, DW1
Lee, SB1
Kwak, IS1
Jia, G1
Habibi, J1
Bostick, BP1
DeMarco, VG1
Aroor, AR1
Hayden, MR1
Whaley-Connell, AT1
Sowers, JR1
Sibunruang, C1
Ingsathit, A1
Kantachuvesiri, P1
Radinahamed, P1
Rattanasiri, S1
Pootracool, P1
Kijvikai, K1
Sumethkul, V1
Kantachuvesiri, S1
Yang, T1
Xiong, C1
Chin, YE1
Cheng, SB1
Lin, L1
Yang, J2
Zhang, J1
Li, K1
Huo, B1
Dai, H1
Zhang, W1
Tan, W1
He, Y1
Ai, Z1
Xu, R1
Liu, W1
Zhou, Q1
Li, B1
Huang, F1
Yu, X1
Yang, Q1
Abdel-Daim, MM1
El-Sayed, YS1
Eldaim, MA1
Ibrahim, A1
Braga, TT1
Forni, MF1
Correa-Costa, M1
Ramos, RN1
Barbuto, JA1
Branco, P1
Castoldi, A1
Hiyane, MI1
Davanso, MR1
Latz, E1
Franklin, BS1
Kowaltowski, AJ1
Camara, NO1
Lo, HC1
Wang, YH1
Chiou, HY1
Lai, SH1
Yang, Y1
Yang, Z1
Xiaohua, W1
Lei, J1
Ruoyun, T1
Mingxia, X1
Weichun, H1
Li, F1
Ping, W1
Junwei, Y1
Chen, CC1
Hsu, YJ1
Lee, TM1
Mazali, FC1
Mazzali, M2
Butler, R1
Inzunza, J1
Suzuki, H1
Fujii-Kuriyama, Y1
Warner, M1
Gustafsson, JÅ1
He, J1
Sun, S1
Yu, M1
Pei, X1
Zhu, B1
Wu, J1
Zhao, W1
Iwata, A1
Miura, S1
Ike, A1
Sugihara, M1
Nishikawa, H1
Kawamura, A1
Saku, K1
Stabellini, N1
Storari, A1
Aleotti, A1
Fiocchi, O1
Tarroni, G1
Fabbian, F1
Gilli, P1
Gentile, S1
Turco, S1
Torella, R1
George, J1
Chandrakasan, G1
Hughes, J1
Kim, YG1
Jefferson, JA1
Gordon, KL1
Lan, HY1
Kivlighn, S1
Zhang, K1
Liu, L1
Han, Y1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645]Phase 4100 participants (Anticipated)Interventional2018-12-01Not yet recruiting
Value of Uric Acid as Early Predictor of Lupus Nephritis in Assiut University Hospital[NCT05402735]100 participants (Anticipated)Observational2022-06-15Recruiting
Pediatric Hypertension Registry (PHREG)[NCT03305562]179 participants (Actual)Observational [Patient Registry]2017-09-20Terminated (stopped due to Study was a pilot study and the investigators received funding to initiate the main study)
The Role of the Renin-Angiotensin System in Pediatric Primary Hypertension (PHRAS)[NCT03310684]160 participants (Anticipated)Observational2018-12-03Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for uric acid and Cirrhosis

ArticleYear
Mechanistic insights into hyperuricemia-associated renal abnormalities with special emphasis on epithelial-to-mesenchymal transition: Pathologic implications and putative pharmacologic targets.
    Pharmacological research, 2020, Volume: 161

    Topics: Animals; Biomarkers; Cytokines; Epithelial-Mesenchymal Transition; Febuxostat; Fibrosis; Gout Suppre

2020
Endogenous Fructose Metabolism Could Explain the Warburg Effect and the Protection of SGLT2 Inhibitors in Chronic Kidney Disease.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Cell Hypoxia; Diabetes Mellitus; Disease Progression; Fibrosis; Fructose; Glycolysis; Human

2021
The Anticipated Renoprotective Effects of Sodium-glucose Cotransporter 2 Inhibitors.
    Internal medicine (Tokyo, Japan), 2018, Aug-01, Volume: 57, Issue:15

    Topics: Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Fibrosis; Glucose; Humans; Hypoglycemic Agen

2018
Carbohydrate intake and nonalcoholic fatty liver disease.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:4

    Topics: Animals; Beverages; Clinical Trials as Topic; Dietary Carbohydrates; Fatty Liver; Fibrosis; Humans;

2013
The role of uric acid in kidney fibrosis: experimental evidences for the causal relationship.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Disease Models, Animal; Fibrosis; Humans; Inflammation; Renal Insufficiency, Chronic; Uric

2014

Other Studies

56 other studies available for uric acid and Cirrhosis

ArticleYear
Pharmacologic inhibiting STAT3 delays the progression of kidney fibrosis in hyperuricemia-induced chronic kidney disease.
    Life sciences, 2021, Nov-15, Volume: 285

    Topics: Aminosalicylic Acids; Animals; Benzenesulfonates; Disease Models, Animal; Fibrosis; Hyperuricemia; K

2021
Calcitriol Treatment Attenuates Uric Acid-Induced Kidney Injury via Super Oxide Dismutase-1 (SOD-1) Upregulation and Fibrosis Reduction
    Iranian biomedical journal, 2021, 11-01, Volume: 25, Issue:6

    Topics: Animals; Calcitriol; Fibrosis; Hyperuricemia; Mice; Superoxide Dismutase-1; Up-Regulation; Uric Acid

2021
Goose nephritic astrovirus infection increases autophagy, destroys intercellular junctions in renal tubular epithelial cells, and damages podocytes in the kidneys of infected goslings.
    Veterinary microbiology, 2021, Volume: 263

    Topics: Animals; Astroviridae Infections; Autophagy; Avastrovirus; Fibrosis; Geese; Intercellular Junctions;

2021
A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:1

    Topics: Adult; Atrophy; Female; Fibrinogen; Fibrosis; Glomerulonephritis, IGA; Humans; Kidney Tubules; Male;

2022
CD137L-macrophage induce lymphatic endothelial cells autophagy to promote lymphangiogenesis in renal fibrosis.
    International journal of biological sciences, 2022, Volume: 18, Issue:3

    Topics: 4-1BB Ligand; Animals; Autophagy; Endothelial Cells; Female; Fibrosis; Glomerulonephritis, IGA; Huma

2022
Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Animals; Fibrosis; Hyperuricemia; Inflammation; Iridoids; Kidney Diseases; Mice; Molecular Docking S

2022
Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis.
    Pharmacological research, 2022, Volume: 182

    Topics: Animals; Fibrosis; Humans; Hyperuricemia; Kidney; Kidney Diseases; Mice; Uric Acid

2022
Chlorogenic Acid Prevents Hyperuricemia Nephropathy via Regulating TMAO-Related Gut Microbes and Inhibiting the PI3K/AKT/mTOR Pathway.
    Journal of agricultural and food chemistry, 2022, Aug-24, Volume: 70, Issue:33

    Topics: Animals; Chlorogenic Acid; Fibrosis; Gastrointestinal Microbiome; Hyperuricemia; Mammals; Methylamin

2022
Fufang Zhenzhu Tiaozhi capsule ameliorates hyperuricemic nephropathy by inhibition of PI3K/AKT/NF-κB pathway.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Animals; Fibrosis; Hyperuricemia; Inflammation; Kidney; Mice; NF-kappa B; Phosphatidylinositol 3-Kin

2022
AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model.
    European journal of medical research, 2022, Sep-10, Volume: 27, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Fibrosis; Hyperuricemia; Kidney; Kid

2022
Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders.
    Journal of environmental sciences (China), 2023, Volume: 124

    Topics: Animals; Anti-Infective Agents; Corn Oil; Creatinine; Cytokines; Dimethyl Sulfoxide; Fatty Acids; Fi

2023
Moderate hyperuricaemia ameliorated kidney damage in a low-renin model of experimental renal insufficiency.
    Basic & clinical pharmacology & toxicology, 2023, Volume: 132, Issue:1

    Topics: Animals; Fibrosis; Hyperuricemia; Inflammation; Kidney; Kidney Diseases; Nephrectomy; Oxonic Acid; R

2023
Uric acid significantly correlates with the presence of low-voltage areas at the endocardial mapping in patients with non-valvular atrial fibrillation.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2023, Volume: 33, Issue:7

    Topics: Atrial Fibrillation; Cross-Sectional Studies; Fibrosis; Heart Atria; Humans; Uric Acid

2023
Chloroquine inhibits NLRP3 inflammasomes activation and alleviates renal fibrosis in mouse model of hyperuricemic nephropathy with aggravation by a high-fat-diet.
    International immunopharmacology, 2023, Volume: 120

    Topics: Animals; Chloroquine; Creatinine; Diet, High-Fat; Fibrosis; Hyperuricemia; Inflammasomes; Kidney; Ki

2023
Fucoidan from
    Journal of agricultural and food chemistry, 2023, Aug-02, Volume: 71, Issue:30

    Topics: Animals; Fibrosis; Hyperuricemia; Janus Kinase 2; Kidney; Laminaria; Mice; Polysaccharides; Renal In

2023
Fuling-Zexie formula attenuates hyperuricemia-induced nephropathy and inhibits JAK2/STAT3 signaling and NLRP3 inflammasome activation in mice.
    Journal of ethnopharmacology, 2024, Jan-30, Volume: 319, Issue:Pt 2

    Topics: Albumins; Animals; Chromatography, Liquid; Fibrosis; Hyperuricemia; Inflammasomes; Inflammation; Int

2024
Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Volume: 66

    Topics: Animals; Cell Line; Cytokines; Fibrosis; Humans; Hyperuricemia; Inflammasomes; Inflammation; Kidney

2020
Multiple-Purpose Connectivity Map Analysis Reveals the Benefits of Esculetin to Hyperuricemia and Renal Fibrosis.
    International journal of molecular sciences, 2020, Oct-18, Volume: 21, Issue:20

    Topics: Animals; Cell Nucleus; Disease Models, Animal; Down-Regulation; Fibrosis; Hep G2 Cells; Humans; Hype

2020
Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications.
    Cardiovascular toxicology, 2021, Volume: 21, Issue:3

    Topics: Actins; Animals; Apoptosis; Atrial Fibrillation; Atrial Remodeling; bcl-2-Associated X Protein; Benz

2021
Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome.
    Molecules (Basel, Switzerland), 2021, Feb-06, Volume: 26, Issue:4

    Topics: Animals; Cytoprotection; Fibrosis; Inflammation; Kidney; Male; Metabolic Syndrome; Morpholines; Pyra

2021
Nifuroxazide suppresses UUO-induced renal fibrosis in rats via inhibiting STAT-3/NF-κB signaling, oxidative stress and inflammation.
    Life sciences, 2021, May-01, Volume: 272

    Topics: Animals; Fibrosis; Hydroxybenzoates; Inflammation; Kidney; Kidney Diseases; Male; NF-kappa B; Nitrof

2021
Natural flavonol fisetin attenuated hyperuricemic nephropathy via inhibiting IL-6/JAK2/STAT3 and TGF-β/SMAD3 signaling.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 87

    Topics: Administration, Oral; Animals; Fibrosis; Flavonols; Gene Expression Regulation; Hyperuricemia; Inter

2021
Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 87

    Topics: Animals; Apigenin; beta Catenin; Creatinine; Dose-Response Relationship, Drug; Fibrosis; Glucose Tra

2021
The nephroprotective properties of taurine-amikacin treatment in rats are mediated through HSP25 and TLR-4 regulation.
    The Journal of antibiotics, 2021, Volume: 74, Issue:9

    Topics: Amikacin; Animals; Anti-Bacterial Agents; Apoptosis; Blood Urea Nitrogen; Creatinine; Dose-Response

2021
Mesenchymal stem cells transplantation attenuates hyperuricemic nephropathy in rats.
    International immunopharmacology, 2021, Volume: 99

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Culture Techniques; Cell Survival; Fibrosis; Hyperurice

2021
microRNA-199a downregulation alleviates hyperuricemic nephropathy
    Journal of receptor and signal transduction research, 2022, Volume: 42, Issue:4

    Topics: Animals; beta Catenin; Down-Regulation; Fibrosis; Hyperuricemia; Kidney Diseases; MicroRNAs; PPAR ga

2022
Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney.
    Journal of molecular histology, 2017, Volume: 48, Issue:3

    Topics: Animals; Caspase 1; Epithelial-Mesenchymal Transition; Fibrosis; Inflammasomes; Inflammation; Kidney

2017
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Animals; Collagen; Disease Progression; Down-Regulation; Drugs, Chinese Herbal; Extracellular Matrix

2017
Hyperuricemia and Progression of Chronic Kidney Disease: Role of Phenotype Transition of Renal Tubular and Endothelial Cells.
    Contributions to nephrology, 2018, Volume: 192

    Topics: Actins; Animals; Antioxidants; Capillaries; Disease Progression; Endothelial Cells; Epithelial-Mesen

2018
Ameliorative effect of ursolic acid on renal fibrosis in adenine-induced chronic kidney disease in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 101

    Topics: Adenine; Animals; Blood Urea Nitrogen; Collagen Type I; Connective Tissue Growth Factor; Creatinine;

2018
Metabolic and cardiovascular effects of chronic mild hyperuricemia in rodents.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2018, Volume: 66, Issue:7

    Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiovascular Diseases; Chronic Disease; Fasti

2018
Association between post-transplant uric acid level and renal allograft fibrosis: Analysis using Banff pathologic scores from renal biopsies.
    Scientific reports, 2018, 08-02, Volume: 8, Issue:1

    Topics: Adult; Allografts; Biopsy; Female; Fibrosis; Graft Survival; Humans; Kidney; Kidney Transplantation;

2018
Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Animals; Blueberry Plants; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Fibronectins;

2019
Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia.
    American journal of physiology. Renal physiology, 2019, 03-01, Volume: 316, Issue:3

    Topics: Animals; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Fibroblasts; Fibrosis; Histones; Hype

2019
Theacrine attenuates myocardial fibrosis after myocardial infarction via the SIRT3/β-catenin/PPARγ pathway in estrogen-deficient mice.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:12

    Topics: Administration, Oral; Animals; Apoptosis; beta Catenin; Disease Models, Animal; Echocardiography; Es

2019
Tumoral calcinosis form of hydroxyapatite deposition disease in related red-bellied short-necked turtles, Emydura subglobosa.
    Veterinary pathology, 2013, Volume: 50, Issue:3

    Topics: Animals; Apatites; Calcinosis; Calcium; Calcium Pyrophosphate; Crystallography; Durapatite; Female;

2013
Salivary antioxidants in patients with systemic sclerosis.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:1

    Topics: Adult; Aged; Antioxidants; Atrophy; Case-Control Studies; Colorimetry; DMF Index; Female; Fibrosis;

2014
Uric acid promotes left ventricular diastolic dysfunction in mice fed a Western diet.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:3

    Topics: Allopurinol; Animals; Biomarkers; Diet, Western; Dietary Fats; Dietary Sucrose; Disease Models, Anim

2015
Increased urine transforming growth factor β1 (TGF-β1) and serum uric acid are associated with an early decline of glomerular filtration rate in kidney transplant recipients.
    Transplantation proceedings, 2015, Volume: 47, Issue:2

    Topics: Adult; Allografts; Female; Fibrosis; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney;

2015
EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy.
    Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:11

    Topics: Animals; Chemokines; Cytokines; Disease Progression; ErbB Receptors; Fibroblasts; Fibrosis; Gefitini

2015
Nocturnal and Circadian Rhythm of Blood Pressure Is Associated with Renal Structure Damage and Function in Patients with IgAN.
    Archives of medical research, 2016, Volume: 47, Issue:1

    Topics: Adolescent; Adult; Aorta, Thoracic; Asian People; Blood Pressure; Blood Pressure Monitoring, Ambulat

2016
Clinicopathologic features of IgA nephropathy patients with different levels of proteinuria.
    Clinical nephrology, 2016, Volume: 86, Issue:7

    Topics: Adult; Atrophy; Biopsy; Female; Fibrosis; Glomerular Filtration Rate; Glomerulonephritis, IGA; Glome

2016
Nephroprotective efficacy of ceftriaxone against cisplatin-induced subchronic renal fibrosis in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:3

    Topics: Actins; Animals; Biomarkers; Bromodeoxyuridine; Ceftriaxone; Cell Proliferation; Cisplatin; Creatini

2017
Soluble Uric Acid Activates the NLRP3 Inflammasome.
    Scientific reports, 2017, 01-13, Volume: 7

    Topics: Animals; Caspase 1; Cells, Cultured; Disease Models, Animal; Fibrosis; Inflammasomes; Interleukin-1b

2017
Relative efficacy of casein or soya protein combined with palm or safflower-seed oil on hyperuricaemia in rats.
    The British journal of nutrition, 2010, Volume: 104, Issue:1

    Topics: Albumins; Analysis of Variance; Animals; Blood Urea Nitrogen; Caseins; Cholesterol; Creatinine; Diet

2010
Uric acid increases fibronectin synthesis through upregulation of lysyl oxidase expression in rat renal tubular epithelial cells.
    American journal of physiology. Renal physiology, 2010, Volume: 299, Issue:2

    Topics: Animals; Blotting, Western; Cell Line; Disease Models, Animal; Epithelial Cells; Extracellular Matri

2010
Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Allopurinol; Analysis of Variance; Animals; Antioxidants; Atrasentan; Biomarkers; Cyclic N-Oxides; D

2011
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy.
    Nephron. Experimental nephrology, 2012, Volume: 120, Issue:1

    Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis;

2012
Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jan-24, Volume: 109, Issue:4

    Topics: Animals; Apoptosis; Cadherins; Fibrosis; Immunohistochemistry; In Situ Nick-End Labeling; Macrophage

2012
Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model.
    Nephrology (Carlton, Vic.), 2012, Volume: 17, Issue:5

    Topics: Animals; Atrophy; Biomarkers; Blood Urea Nitrogen; Bone Marrow Transplantation; Cell-Derived Micropa

2012
Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin.
    Coronary artery disease, 2012, Volume: 23, Issue:5

    Topics: Aged; Angina, Stable; Atorvastatin; Biomarkers; C-Reactive Protein; Case-Control Studies; Chi-Square

2012
Familial interstitial nephropathy without hyperuricemia.
    Nephron, 1994, Volume: 66, Issue:2

    Topics: Adult; Aged; Biopsy; Family Health; Female; Fibrosis; Humans; Kidney; Kidney Diseases; Male; Middle

1994
Diabetes mellitus after liver transplantation: a possible relation with the nutritional status.
    Diabetes research and clinical practice, 1998, Volume: 41, Issue:3

    Topics: Albuminuria; Bilirubin; Blood Glucose; Blood Proteins; C-Peptide; Cyclosporine; Diabetes Mellitus, T

1998
Biochemical abnormalities during the progression of hepatic fibrosis induced by dimethylnitrosamine.
    Clinical biochemistry, 2000, Volume: 33, Issue:7

    Topics: Animals; Blood Glucose; Cholesterol; Creatinine; Dimethylnitrosamine; Fibrosis; Hydroxyproline; Insu

2000
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Animals; Blood Pressure; Crystallization; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Ma

2001
[Pleural effusion of gout].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2000, Volume: 23, Issue:6

    Topics: Adult; Aged; Female; Fibrosis; Gout; Humans; Lung; Lung Diseases; Male; Middle Aged; Pleural Effusio

2000