Page last updated: 2024-10-20

uric acid and Chorea

uric acid has been researched along with Chorea in 38 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.

Research Excerpts

Excerpt	Relevance	Reference
"Certain gouty subjects with excessive de novo purine synthesis are deficient in hypoxanthineguanine phosphoribosyltransferase (HG-PRTase [EC 2."	3.65	Mechanism of excessive purine biosynthesis in hypoxanthine-guanine phosphoribosyltransferase deficiency. ( Sorensen, LB, 1970)
"A patient with polycythemia rubra vera and chorea is described and the literature on this rare combination is reviewed."	1.25	Chorea complicating polycythemia rubra vera. ( Ashenhurst, EM, 1972)

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
LESCH, M	2
NYHAN, WL	3
HOEFNAGEL, D	1
ANDREW, ED	1
MIREAULT, NG	1
BERNDT, WO	1
Michener, WM	1
Marie, J	1
Royer, P	1
Rappaport, R	1
Gottlieb, RP	1
Koppel, MM	1
Bakay, B	1
Nissinen, E	1
Borden, M	1
Page, T	1
Proctor, P	1
McGinness, JE	1
Beardmore, TD	1
Fox, IH	2
Kelley, WN	3
Wyngaarden, JB	1
McDonald, JA	1
Reed, WB	1
Leiber, B	1
Olbrich, G	1
Sweetman, L	1
Wada, Y	2
Emmerson, BT	1
Wallace, DC	1
Thompson, CJ	1
Láhoda, F	1
Ross, A	1
Ashenhurst, EM	1
Kastner, C	1
Berman, PH	1
Balis, ME	1
Dancis, J	1
Kaiser, W	1
Zöllner, N	1
Jones, CE	1
Smith, EE	1
Hicks, W	1
Crowell, JW	1
Sorensen, LB	2
van der Zee, SP	1
Lommen, EJ	1
Trijbels, JM	1
Schretlen, ED	1
Ghadimi, H	1
Bhalla, CK	1
Kirchenbaum, DM	1
Choi, KW	1
Bloom, AD	1
Boyle, JA	1
Raivio, KO	1
Astrin, KH	1
Schulman, JD	1
Graf, ML	1
Seegmiller, JE	2
Jacobsen, CB	1
Omura, GA	1
Jolley, RL	1
Scott, CD	1
Chow, DC	1
Kawahara, FS	1
Saunders, T	1
Sarto, GE	1
Dizmang, LH	1
Cheatham, CF	1
Newcombe, DS	1
Arima, M	1
Aoki, N	1
Ono, K	1
Vaisrub, S	1
Benke, PJ	1
Dörner, K	1
Manzke, H	1
Byrne, WL	1

Reviews

2 reviews available for uric acid and Chorea

Article	Year
[Congenital disorder of purine metabolism]. Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:5 Topics: Athetosis; Chorea; Compulsive Behavior; Humans; Intellectual Disability; Metabolism, Inborn Errors;	1970
[Treatment of congenital purine-pyrimidine metabolism anomalies]. Horumon to rinsho. Clinical endocrinology, 1971, Volume: 19, Issue:1 Topics: Athetosis; Chorea; Compulsive Behavior; Gout; Humans; Intellectual Disability; Orotic Acid; Purine-P	1971

Trials

1 trial available for uric acid and Chorea

Article	Year
Effects of the uricogenic agent, 2-ethylamino-1,3,4-thiadiazole in hypoxanthine-guanine phosphoribosyl transferase deficiency. Metabolism: clinical and experimental, 1968, Volume: 17, Issue:10 Topics: Adolescent; Athetosis; Azoles; Carbon Isotopes; Cerebral Palsy; Child; Chorea; Clinical Trials as To	1968

Other Studies

35 other studies available for uric acid and Chorea

Article	Year
A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION. The American journal of medicine, 1964, Volume: 36 Topics: Athetosis; Biomedical Research; Blood Chemical Analysis; Central Nervous System Diseases; Cerebral P	1964
HEREDITARY CHOREOATHETOSIS, SELF-MUTILATION AND HYPERURICEMIA IN YOUNG MALES. The New England journal of medicine, 1965, Jul-15, Volume: 273 Topics: Athetosis; Blood; Child; Chorea; Colorimetry; Genetics, Medical; Humans; Hyperuricemia; Infant; Male	1965
Hyperuricemia and mental retardation with athetosis and self-mutilation. American journal of diseases of children (1960), 1967, Volume: 113, Issue:2 Topics: Allopurinol; Athetosis; Body Height; Body Weight; Child; Child, Preschool; Chorea; Humans; Infant; I	1967
[Congenital hyperuricemia with neurologic, renal and blood disturbances]. Archives francaises de pediatrie, 1967, Volume: 24, Issue:5 Topics: Adolescent; Allopurinol; Anemia, Macrocytic; Athetosis; Chorea; Gout; Humans; Intellectual Disabilit	1967
Hyperuricaemia and choreoathetosis in a child without mental retardation or self-mutilation - a new HPRT variant. Journal of inherited metabolic disease, 1982, Volume: 5, Issue:4 Topics: Adolescent; Athetosis; Chorea; Erythrocytes; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransfe	1982
Levodopa side-effects and the Lesch-Nyhan syndrome. Lancet (London, England), 1970, Dec-26, Volume: 2, Issue:7687 Topics: Athetosis; Chorea; Compulsive Behavior; Diagnosis, Differential; Dihydroxyphenylalanine; Humans; Int	1970
Effect of allopurinol on pyrimidine metabolism in the Lesch-Nyhan syndrome. Lancet (London, England), 1970, Oct-17, Volume: 2, Issue:7677 Topics: Allopurinol; Athetosis; Child; Chorea; Compulsive Behavior; Humans; Intellectual Disability; Orotic	1970
Regulation of purine biosynthesis in cultured human cells. I. Effects of orotic acid. Biochimica et biophysica acta, 1970, Sep-22, Volume: 215, Issue:3 Topics: Adolescent; Adult; Athetosis; Cell Line; Chorea; Compulsive Behavior; Culture Techniques; Fibroblast	1970
Lesch-Nyhan syndrome: altered kinetic properties of mutant enzyme. Science (New York, N.Y.), 1971, Feb-19, Volume: 171, Issue:3972 Topics: Athetosis; Child; Chorea; Compulsive Behavior; Diphosphates; Erythrocytes; Guanine; Humans; Hypoxant	1971
[Genetic aspects in dermatology]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1970, Volume: 21, Issue:1 Topics: Adult; Alopecia; Amino Acid Metabolism, Inborn Errors; Athetosis; Carotid Body Tumor; Chorea; Chromo	1970
[Lesch-Nyhan syndrome]. Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:1 Topics: Aggression; Athetosis; Bites, Human; Chorea; Glycine; Humans; Hyperlipidemias; Intellectual Disabili	1973
Partial deficiency of hypoxanthine-guanine phosphoribosyltransferase: intermediate enzyme deficiency in heterozygote red cells. Annals of internal medicine, 1972, Volume: 76, Issue:2 Topics: Adolescent; Adult; Aged; Athetosis; Child; Child, Preschool; Chorea; Compulsive Behavior; Erythrocyt	1972
[Neurological complications in uricopathy]. Munchener medizinische Wochenschrift (1950), 1972, Mar-10, Volume: 114, Issue:10 Topics: Adult; Athetosis; Cardiovascular Diseases; Chorea; Compulsive Behavior; Female; Humans; Intellectual	1972
Chorea complicating polycythemia rubra vera. Canadian Medical Association journal, 1972, Sep-09, Volume: 107, Issue:5 Topics: Aged; Chorea; Erythrocyte Count; Hematocrit; Hemoglobinometry; Humans; Leukocyte Count; Male; Polycy	1972
[Juvenile hyperuricemia, gout and cerebral palsy (Lesch-Nyhan syndrome)]. Zeitschrift fur Kinderheilkunde, 1969, Oct-09, Volume: 107, Issue:1 Topics: Adolescent; Allopurinol; Athetosis; Cerebral Palsy; Chorea; Gout; Humans; Male; Uric Acid	1969
A method for the prenatal diagnosis of the Lesch-Nyhan syndrome using fresh amniotic cells. Transactions of the American Neurological Association, 1969, Volume: 94 Topics: Amniotic Fluid; Athetosis; Chorea; Female; Fetal Diseases; Fetus; Gestational Age; Humans; Intellect	1969
[Lesh-Nyhan syndrome. A congenital defect of purine metabolism with the clinical symptoms of gout and central nervous disorders]. Deutsche medizinische Wochenschrift (1946), 1970, May-08, Volume: 95, Issue:19 Topics: Athetosis; Child, Preschool; Chorea; Compulsive Behavior; Erythrocytes; Female; Humans; Infant; Inte	1970
Determination of urinary purines in hyperuricosuric children by thin-layer chromatography. The Journal of laboratory and clinical medicine, 1970, Volume: 76, Issue:1 Topics: Allopurinol; Athetosis; Child; Child, Preschool; Chorea; Chromatography, Thin Layer; Densitometry; H	1970
Mechanism of excessive purine biosynthesis in hypoxanthine-guanine phosphoribosyltransferase deficiency. The Journal of clinical investigation, 1970, Volume: 49, Issue:5 Topics: Adult; Allopurinol; Athetosis; Carbon Isotopes; Child; Chorea; Compulsive Behavior; Deficiency Disea	1970
The influence of adenine on the clinical features and purine metabolism in the Lesch-Nyhan syndrome. Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:3 Topics: Adenine; Allopurinol; Athetosis; Bone Marrow; Carbon Isotopes; Child; Child, Preschool; Chorea; Comp	1970
The significance of the deficiency state in Lesch-Nyhan disease. Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:3 Topics: Allopurinol; Amino Acids; Athetosis; Carbon Isotopes; Child, Preschool; Chorea; Compulsive Behavior;	1970
Biochemically marked lymphocytoid lines: establishment of Lesch-Nyhan cells. Science (New York, N.Y.), 1970, Oct-02, Volume: 170, Issue:3953 Topics: Athetosis; Cell Line; Chorea; Compulsive Behavior; Culture Techniques; Humans; Hypoxanthines; Immuno	1970
Lesch-Nyhan syndrome: preventive control by prenatal diagnosis. Science (New York, N.Y.), 1970, Aug-14, Volume: 169, Issue:3946 Topics: Adenine; Amniotic Fluid; Athetosis; Autoradiography; Basal Ganglia; Carbon Isotopes; Cerebellum; Cer	1970
Diagnosis of the Lesch-Nyhan syndrome. JAMA, 1970, Jul-13, Volume: 213, Issue:2 Topics: Athetosis; Chorea; Compulsive Behavior; Humans; Intellectual Disability; Purines; Self Mutilation; T	1970
Preliminary results from high-resolution analyses of ultraviolet-absorbing and carbohydrate constituents in several pathologic body fluids. Clinical chemistry, 1970, Volume: 16, Issue:8 Topics: Adolescent; Adult; Alkaptonuria; Allopurinol; Amniotic Fluid; Athetosis; Carbohydrates; Chorea; Chro	1970
A new assay method for hypoxanthine-guanine phosphoribosyltransferase. The Journal of laboratory and clinical medicine, 1970, Volume: 76, Issue:5 Topics: Adenine; Adenine Nucleotides; Athetosis; Carbon Isotopes; Chorea; Chromatography; Compulsive Behavio	1970
Prenatal diagnosis of genetic disorders by amniocentesis. Wisconsin medical journal, 1970, Volume: 69, Issue:12 Topics: Adult; Amniotic Fluid; Athetosis; Chorea; Chromosome Aberrations; Chromosome Disorders; Compulsive B	1970
The Lesch-Nyhan syndrome. The American journal of psychiatry, 1970, Volume: 127, Issue:5 Topics: Adolescent; Aggression; Athetosis; Blood Specimen Collection; Child; Child Development; Chorea; Comp	1970
The urinary excretion of aminoimidazolecarboxamide in the Lesch-Nyhan syndrome. Pediatrics, 1970, Volume: 46, Issue:4 Topics: Adolescent; Athetosis; Child; Child, Preschool; Chorea; Compulsive Behavior; Female; Folic Acid; Hum	1970
Lesch-Nyhan syndrome. Paediatria Universitatis Tokyo, 1970, Volume: 18 Topics: Allopurinol; Athetosis; Benzofurans; Brain; Child; Child, Preschool; Chorea; Compulsive Behavior; Er	1970
Lesch-Nyhan syndrome: preventive control. Science (New York, N.Y.), 1970, Dec-18, Volume: 170, Issue:3964 Topics: Athetosis; Chorea; Compulsive Behavior; Humans; Intellectual Disability; Purine-Pyrimidine Metabolis	1970
Inborn terror of metabolism. JAMA, 1970, Dec-21, Volume: 214, Issue:12 Topics: Athetosis; Chorea; Compulsive Behavior; Female; Humans; Intellectual Disability; Male; Pregnancy; Pu	1970
Alteration of purine control mechanisms in patients with the Lesch-Nyhan mutation. Wisconsin medical journal, 1971, Volume: 70, Issue:7 Topics: Athetosis; Chorea; Compulsive Behavior; Diseases in Twins; Female; Humans; Infant, Newborn; Intellec	1971
[Simple determination of purines by preparative thin-layer chromatography]. Zeitschrift fur klinische Chemie und klinische Biochemie, 1971, Volume: 9, Issue:1 Topics: Athetosis; Chorea; Chromatography, Thin Layer; Compulsive Behavior; Diagnosis, Differential; Gout; H	1971
Molecular approaches to the central nervous system: AAAS Symposium 29-31 December 1968. Dallas, Texas. Science (New York, N.Y.), 1968, Dec-20, Volume: 162, Issue:3860 Topics: Athetosis; Cerebral Palsy; Chorea; Glucosyltransferases; Humans; Intellectual Disability; Molecular	1968