uric acid has been researched along with Cholestasis in 9 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 64-year-old man with alcoholic liver cirrhosis had a progressive decrease in the serum uric acid (UA) until it became undetectable, an increase renal UA clearance, mild glycosuria with normal serum glucose and a decrease in the tubular reabsorption of phosphate in association with cholestasis secondary to a gallbladder carcinoma." | 7.69 | Severe renal hypouricemia secondary to hyperbilirubinemia. ( Albarran-Hernandez, F; Alvarez de Mon, M; Arranz-Caso, JA; Barrio, V; Cuadrado-Gomez, LM; Fernández de Paz, FJ, 1995) |
| "Changes in plasma uric acid concentration (UA, mumol/L) in postoperative and critical illness have pathophysiological and clinical relevance and may alter plasma antioxidant capacity." | 3.74 | Biochemical and clinical correlates of hypouricemia in surgical and critically ill patients. ( Ardito, F; Chiarla, C; Giovannini, I; Giuliante, F; Nuzzo, G; Pallavicini, F; Vellone, M, 2007) |
| "A 64-year-old man with alcoholic liver cirrhosis had a progressive decrease in the serum uric acid (UA) until it became undetectable, an increase renal UA clearance, mild glycosuria with normal serum glucose and a decrease in the tubular reabsorption of phosphate in association with cholestasis secondary to a gallbladder carcinoma." | 3.69 | Severe renal hypouricemia secondary to hyperbilirubinemia. ( Albarran-Hernandez, F; Alvarez de Mon, M; Arranz-Caso, JA; Barrio, V; Cuadrado-Gomez, LM; Fernández de Paz, FJ, 1995) |
| "Cholestasis is one of the most severe manifestations of liver injury and has limited therapeutic options." | 1.62 | Allopurinol Protects Against Cholestatic Liver Injury in Mice Not Through Depletion of Uric Acid. ( Fan, Y; Li, G; Liu, J; Xu, T; Yu, H; Zhang, C; Zhang, Y; Zhou, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J | 1 |
| Fan, Y | 1 |
| Yu, H | 1 |
| Xu, T | 1 |
| Zhang, C | 1 |
| Zhou, L | 1 |
| Li, G | 1 |
| Zhang, Y | 1 |
| Giovannini, I | 1 |
| Chiarla, C | 1 |
| Giuliante, F | 1 |
| Vellone, M | 1 |
| Ardito, F | 1 |
| Pallavicini, F | 1 |
| Nuzzo, G | 1 |
| Schölmerich, J | 1 |
| Schmidt, K | 1 |
| Kremer, B | 1 |
| Becher, MS | 1 |
| Gerok, W | 1 |
| Arranz-Caso, JA | 1 |
| Fernández de Paz, FJ | 1 |
| Barrio, V | 1 |
| Cuadrado-Gomez, LM | 1 |
| Albarran-Hernandez, F | 1 |
| Alvarez de Mon, M | 1 |
| Park, EJ | 1 |
| Ko, G | 1 |
| Kim, J | 1 |
| Sohn, DH | 1 |
| Bairaktari, E | 1 |
| Liamis, G | 1 |
| Tsolas, O | 1 |
| Elisaf, M | 1 |
| Warren, DJ | 1 |
| Winney, RJ | 1 |
| Beveridge, GW | 1 |
| Lillie, RD | 1 |
| Pizzolato, P | 1 |
| Roszkowski, I | 1 |
| Wójcicka, J | 1 |
9 other studies available for uric acid and Cholestasis
| Article | Year |
|---|---|
Allopurinol Protects Against Cholestatic Liver Injury in Mice Not Through Depletion of Uric Acid.
Topics: 1-Naphthylisothiocyanate; Allopurinol; Animals; Cholestasis; Cholestasis, Intrahepatic; Liver; Mice; | 2021 |
Biochemical and clinical correlates of hypouricemia in surgical and critically ill patients.
Topics: Aged; Albumins; Antioxidants; Blood Chemical Analysis; Cholestasis; Critical Illness; Female; Humans | 2007 |
[Different effect of taurolithocholate and chenodeoxycholate on structure and function of isolated hepatocytes (author's transl)].
Topics: Animals; Aspartate Aminotransferases; Cell Membrane; Chenodeoxycholic Acid; Cholestasis; Dose-Respon | 1981 |
Severe renal hypouricemia secondary to hyperbilirubinemia.
Topics: Bilirubin; Blood Glucose; Cholestasis; Follow-Up Studies; Gallbladder Neoplasms; Glycosuria; Humans; | 1995 |
Biotransformation of theophylline in cirrhotic rats induced by biliary obstruction.
Topics: Animals; Area Under Curve; Biotransformation; Body Weight; Bronchodilator Agents; Cholestasis; Half- | 1999 |
Partially reversible renal tubular damage in patients with obstructive jaundice.
Topics: Adult; Bile Acids and Salts; Cholestasis; Female; Humans; Kidney Tubules, Proximal; Magnetic Resonan | 2001 |
Oligaemia, renal failure, and jaundice associated with acute pustular psoriasis.
Topics: Acute Disease; Acute Kidney Injury; Anuria; Blood Pressure; Blood Volume; Calcium; Capillary Permeab | 1974 |
Histochemical azo coupling reactions of the pigments of obstructive icterus and of hematoidin. II. Effect of blockade, bleaching and extraction procedures on the pigments and their azo derivatives.
Topics: Acetates; Azo Compounds; Benzoates; Bile Pigments; Caffeine; Cholestasis; Chromates; Histocytochemis | 1970 |
Jaundice in pregnancy. I. Biochemical assays.
Topics: Acid Phosphatase; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Chol | 1968 |