Page last updated: 2024-10-20

uric acid and Cerebral Palsy

uric acid has been researched along with Cerebral Palsy in 19 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
" Hyperuricemia leads to hyperuricuria and uric acid nephrolithiasis."3.74Rare variant of Lesch-Nyhan syndrome without self-mutilation or nephrolithiasis. ( Kersnik Levart, T, 2007)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199013 (68.42)18.7374
1990's0 (0.00)18.2507
2000's2 (10.53)29.6817
2010's3 (15.79)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Ambarsari, CG1
Cahyadi, D1
Sari, L1
Satria, O1
Sahli, F1
Darmadi, TL1
Kadaristiana, A1
Ayyavoo, A1
Derraik, JG1
Hofman, PL1
Cutfield, WS1
Schoendorfer, N1
Tinggi, U1
Sharp, N2
Boyd, R1
Vitetta, L2
Davies, PS2
Schoendorfer, NC1
Obeid, R1
Moxon-Lester, L1
Boyd, RN1
LESCH, M2
NYHAN, WL2
HOEFNAGEL, D1
Aycicek, A1
Iscan, A1
Kersnik Levart, T1
van der Zee, SP1
Schretlen, ED1
Monnens, LA1
Kekre, S1
Singh, SD1
Chhaparwal, BC1
Pohowalla, JN1
Sweetman, L1
Seegmiller, JE2
Kastner, C1
Manzke, H1
Becker, MH1
Wallin, JK1
Kaufman, JM1
Greene, ML1
Byrne, WL1
Sass, JK1
Itabashi, HH1
Dexter, RA1
Dodge, PR1

Reviews

2 reviews available for uric acid and Cerebral Palsy

ArticleYear
Uric acid studies in serum and cerebrospinal fluid in neurological disorders with mental retardation.
    Indian pediatrics, 1971, Volume: 8, Issue:10

    Topics: Carbohydrate Metabolism, Inborn Errors; Central Nervous System Diseases; Cerebral Palsy; Child; Chil

1971
Biochemical and genetic studies of an X-linked neurological disease (The Lesch-Nyhan syndrome).
    Harvey lectures, 1971, Volume: 65

    Topics: Animals; Athetosis; Cells, Cultured; Cerebral Palsy; Child; Disease Models, Animal; Feedback; Female

1971

Trials

1 trial available for uric acid and Cerebral Palsy

ArticleYear
Effects of the uricogenic agent, 2-ethylamino-1,3,4-thiadiazole in hypoxanthine-guanine phosphoribosyl transferase deficiency.
    Metabolism: clinical and experimental, 1968, Volume: 17, Issue:10

    Topics: Adolescent; Athetosis; Azoles; Carbon Isotopes; Cerebral Palsy; Child; Chorea; Clinical Trials as To

1968

Other Studies

16 other studies available for uric acid and Cerebral Palsy

ArticleYear
Late diagnosis of Lesch-Nyhan disease complicated with end-stage renal disease and tophi burst: a case report.
    Renal failure, 2020, Volume: 42, Issue:1

    Topics: Adolescent; Allopurinol; Cerebral Palsy; Delayed Diagnosis; Exons; Gout Suppressants; Humans; Hypoxa

2020
Postterm births: are prolonged pregnancies too long?
    The Journal of pediatrics, 2014, Volume: 164, Issue:3

    Topics: Body Composition; Body Mass Index; Cerebral Palsy; Child Behavior Disorders; Child, Preschool; Diabe

2014
Protein levels in enteral feeds: do these meet requirements in children with severe cerebral palsy?
    The British journal of nutrition, 2012, Volume: 107, Issue:10

    Topics: Albumins; Blood Proteins; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Creatinine;

2012
Methylation capacity in children with severe cerebral palsy.
    European journal of clinical investigation, 2012, Volume: 42, Issue:7

    Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystath

2012
A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION.
    The American journal of medicine, 1964, Volume: 36

    Topics: Athetosis; Biomedical Research; Blood Chemical Analysis; Central Nervous System Diseases; Cerebral P

1964
THE SYNDROME OF ATHETOID CEREBRAL PALSY, MENTAL DEFICIENCY, SELF-MUTILATION AND HYPERURICEMIA.
    Journal of mental deficiency research, 1965, Volume: 9

    Topics: Athetosis; Blood Chemical Analysis; Blood Urea Nitrogen; Cerebral Palsy; Child; Genetics, Medical; H

1965
Oxidative and antioxidative capacity in children with cerebral palsy.
    Brain research bulletin, 2006, May-31, Volume: 69, Issue:6

    Topics: Albumins; Analysis of Variance; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infant; Lip

2006
Rare variant of Lesch-Nyhan syndrome without self-mutilation or nephrolithiasis.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:11

    Topics: Cerebral Palsy; Child; Diagnosis, Differential; Humans; Kidney; Lesch-Nyhan Syndrome; Male; Nephroca

2007
Megaloblastic anaemia in the Lesch-Nyhan syndrome.
    Lancet (London, England), 1968, Jun-29, Volume: 1, Issue:7557

    Topics: Adenine; Anemia, Macrocytic; Cerebral Palsy; Child; Humans; Intellectual Disability; Male; Movement

1968
[Juvenile hyperuricemia, gout and cerebral palsy (Lesch-Nyhan syndrome)].
    Zeitschrift fur Kinderheilkunde, 1969, Oct-09, Volume: 107, Issue:1

    Topics: Adolescent; Allopurinol; Athetosis; Cerebral Palsy; Chorea; Gout; Humans; Male; Uric Acid

1969
[Hyperuricemia with cerebral paresis. Syndrome of a hereditary purine metabolic disorder].
    Helvetica paediatrica acta, 1967, Volume: 22, Issue:3

    Topics: Adolescent; Anemia, Macrocytic; Cerebral Palsy; Child; Child, Preschool; Glycine; Humans; Hyperlipid

1967
Congenital hyperuricosuria. Associated radiologic features.
    Radiologic clinics of North America, 1968, Volume: 6, Issue:2

    Topics: Cerebral Palsy; Child; Finger Injuries; Gout; Hip Dislocation; Humans; Intellectual Disability; Male

1968
Urine uric acid to creatinine rtio--a screening test for inherited disorders of purine metabolism. Phosphoribosyltransferase (PRT) deficiency in X-linked cerebral palsy and in a variant of gout.
    The Journal of pediatrics, 1968, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Cerebral Palsy; Child; Child, Preschool; Creatinine; Diet; Fem

1968
Molecular approaches to the central nervous system: AAAS Symposium 29-31 December 1968. Dallas, Texas.
    Science (New York, N.Y.), 1968, Dec-20, Volume: 162, Issue:3860

    Topics: Athetosis; Cerebral Palsy; Chorea; Glucosyltransferases; Humans; Intellectual Disability; Molecular

1968
Juvenile gout with brain involvement.
    Archives of neurology, 1965, Volume: 13, Issue:6

    Topics: Blood; Brain; Cerebral Palsy; Child; Demyelinating Diseases; Gout; Humans; Intellectual Disability;

1965
Disordered uric acid metabolism and neurologic abnormalities.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:1

    Topics: Blood-Brain Barrier; Cerebral Palsy; Humans; Infant; Intellectual Disability; Male; Movement Disorde

1966