Page last updated: 2024-10-20

uric acid and Cerebral Hemorrhage

uric acid has been researched along with Cerebral Hemorrhage in 25 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"The relationship between serum uric acid (UA) and the risk of intracerebral hemorrhage (ICH) remains controversial."8.98Serum uric acid concentrations and risk of intracerebral hemorrhage: A systematic review and meta-analysis. ( Liang, Y; Lin, J; Qu, H; Xu, J; Zhang, X; Zhao, C; Zhao, M; Zhou, Z, 2018)
" Previous studies have shown that high serum uric acid (SUA) levels are an independent risk factor for hypertension, cardiovascular disease (CVD), and ischemic stroke."7.96Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis. ( Bai, CX; Chen, JZ; Ge, J; Hui, RT; Li, H; Liu, TL; Song, L; Song, WH; Sun, YY; Wen, HY; Xiao, N; Xu, HC; Zhang, YH, 2020)
"The relationship between uric acid and stroke prognosis is ambiguous."7.80Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients. ( Jia, Q; Liu, G; Liu, L; Pu, Y; Wang, C; Wang, Y; Wu, H; Zhao, X, 2014)
"Unlike experimental studies indicating a neuroprotective property of uric acid, clinical studies have shown that elevated levels of uric acid are associated with a risk of ischemic stroke."7.79Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke. ( Kim, BJ; Kim, CK; Lee, SH; Ryu, WS, 2013)
"The prognostic significance of uric acid (UA) levels in acute stroke is unclear, so the objective of this study was to determine the association between levels of serum UA (SUA) and mortality in acute stroke."7.74Serum uric acid as an independent predictor of early death after acute stroke. ( Athyros, VG; Gossios, T; Kakafika, A; Karagiannis, A; Krikis, N; Mikhailidis, DP; Moschou, I; Savvatianos, S; Sileli, M; Tziomalos, K; Xochellis, M, 2007)
"The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke."7.73Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study. ( Bos, MJ; Breteler, MM; Hofman, A; Koudstaal, PJ; Witteman, JC, 2006)
"The relationship between serum uric acid (UA) and the risk of intracerebral hemorrhage (ICH) remains controversial."4.98Serum uric acid concentrations and risk of intracerebral hemorrhage: A systematic review and meta-analysis. ( Liang, Y; Lin, J; Qu, H; Xu, J; Zhang, X; Zhao, C; Zhao, M; Zhou, Z, 2018)
" Previous studies have shown that high serum uric acid (SUA) levels are an independent risk factor for hypertension, cardiovascular disease (CVD), and ischemic stroke."3.96Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis. ( Bai, CX; Chen, JZ; Ge, J; Hui, RT; Li, H; Liu, TL; Song, L; Song, WH; Sun, YY; Wen, HY; Xiao, N; Xu, HC; Zhang, YH, 2020)
"Elevated serum uric acid (UA) is known to be associated with stroke."3.85Sex-dependent effects of uric acid on cerebral microbleed: a cross-sectional study in the general population. ( Jeong, SM; Kim, S; Kim, SH; Kwon, HM; Lee, JE; Lim, JS; Nam, YS; Park, JH; Yoo, TG, 2017)
"The relationship between uric acid and stroke prognosis is ambiguous."3.80Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients. ( Jia, Q; Liu, G; Liu, L; Pu, Y; Wang, C; Wang, Y; Wu, H; Zhao, X, 2014)
"Unlike experimental studies indicating a neuroprotective property of uric acid, clinical studies have shown that elevated levels of uric acid are associated with a risk of ischemic stroke."3.79Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke. ( Kim, BJ; Kim, CK; Lee, SH; Ryu, WS, 2013)
"The prognostic significance of uric acid (UA) levels in acute stroke is unclear, so the objective of this study was to determine the association between levels of serum UA (SUA) and mortality in acute stroke."3.74Serum uric acid as an independent predictor of early death after acute stroke. ( Athyros, VG; Gossios, T; Kakafika, A; Karagiannis, A; Krikis, N; Mikhailidis, DP; Moschou, I; Savvatianos, S; Sileli, M; Tziomalos, K; Xochellis, M, 2007)
"The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke."3.73Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study. ( Bos, MJ; Breteler, MM; Hofman, A; Koudstaal, PJ; Witteman, JC, 2006)
"The purine metabolite hypoxanthine accumulates with hypoxia ischemia and with reperfusion is converted to uric acid (UA)."3.70Relationship of uric acid concentrations and severe intraventricular hemorrhage/leukomalacia in the premature infant. ( Perlman, JM; Risser, R, 1998)
"Radiological markers for cerebral small vessel disease (SVD) may have different biological underpinnings in their development."1.91Classification of white matter lesions and characteristics of small vessel disease markers. ( Hwang, SA; Jung, KH; Kim, S; Lee, EJ; Lee, WJ; Park, KI; Salat, DH, 2023)
"Uric acid levels were related to serum creatinine (p < 0."1.32Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants. ( Rozycki, HJ; Sysyn, GD, 2003)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's3 (12.00)18.2507
2000's4 (16.00)29.6817
2010's5 (20.00)24.3611
2020's7 (28.00)2.80

Authors

AuthorsStudies
Wang, D1
Wang, Y5
Xu, D1
Zhou, G1
He, S1
Park, KI1
Jung, KH1
Lee, EJ1
Lee, WJ1
Hwang, SA1
Kim, S2
Salat, DH1
Wang, Q1
Li, S1
Sun, M1
Ma, J1
Sun, J1
Fan, M1
Xiao, N1
Liu, TL1
Li, H1
Xu, HC1
Ge, J1
Wen, HY1
Bai, CX1
Song, L1
Sun, YY1
Zhang, YH1
Hui, RT1
Song, WH1
Chen, JZ1
Huang, H2
Huang, G2
Gu, J1
Chen, K2
Huang, Y1
Xu, H2
Jeong, SM1
Yoo, TG1
Nam, YS1
Kim, SH1
Lee, JE1
Lim, JS1
Kwon, HM1
Park, JH1
Zhou, Z1
Liang, Y1
Lin, J1
Zhang, X1
Qu, H1
Xu, J1
Zhao, C1
Zhao, M1
Wu, H1
Jia, Q1
Liu, G1
Liu, L1
Pu, Y1
Zhao, X1
Wang, C1
Chen, H1
Li, F1
Wang, X1
Kong, Y1
Ryu, WS1
Kim, CK1
Kim, BJ1
Lee, SH1
Sysyn, GD1
Rozycki, HJ1
Weir, CJ1
Muir, SW1
Walters, MR1
Lees, KR1
Bos, MJ1
Koudstaal, PJ1
Hofman, A1
Witteman, JC1
Breteler, MM1
Karagiannis, A1
Mikhailidis, DP1
Tziomalos, K1
Sileli, M1
Savvatianos, S1
Kakafika, A1
Gossios, T1
Krikis, N1
Moschou, I1
Xochellis, M1
Athyros, VG1
Kamoi, K1
Toyama, M1
Ishibashi, M1
Yamaji, T1
Beghi, E1
Boglium, G1
Cosso, P1
Fiorelli, G1
Lorini, C1
Mandelli, M1
Bellini, A1
Perlman, JM1
Risser, R1
Ekert, H1
Waters, KD1
Chopra, JS1
Prabhakar, S1
Mertz, DP1
Kendrick, KM1
Leng, G1
Araki, A1
Sako, Y1
Fukushima, Y1
Matsumoto, M1
Asada, T1
Kita, T1
Gertler, MM1
Rusk, HA1
Whiter, HH1
Leetma, HE1
Ehrenkranz, M1

Reviews

2 reviews available for uric acid and Cerebral Hemorrhage

ArticleYear
Serum uric acid concentrations and risk of intracerebral hemorrhage: A systematic review and meta-analysis.
    Atherosclerosis, 2018, Volume: 275

    Topics: Age Factors; Aged; Biomarkers; Cerebral Hemorrhage; Comorbidity; Female; Humans; Hyperuricemia; Male

2018
[Significance of physical activity in the prevention of degenerative heart and vascular diseases?].
    Deutsche medizinische Wochenschrift (1946), 1976, Feb-06, Volume: 101, Issue:6

    Topics: Adult; Age Factors; Arteriosclerosis; Body Weight; Cerebral Hemorrhage; Cerebrovascular Disorders; C

1976

Other Studies

23 other studies available for uric acid and Cerebral Hemorrhage

ArticleYear
Relationship between uric acid and cerebral amyloid angiopathy.
    The International journal of neuroscience, 2023, Volume: 133, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cerebral Amyloid Angiopathy; Cerebral Hemo

2023
Classification of white matter lesions and characteristics of small vessel disease markers.
    European radiology, 2023, Volume: 33, Issue:2

    Topics: Aged; Brain; Cerebral Hemorrhage; Cerebral Small Vessel Diseases; Diabetes Mellitus; Humans; Magneti

2023
Systemic immune-inflammation index may predict the acute kidney injury and prognosis in patients with spontaneous cerebral hemorrhage undergoing craniotomy: a single-center retrospective study.
    BMC nephrology, 2023, 03-25, Volume: 24, Issue:1

    Topics: Acute Kidney Injury; Cerebral Hemorrhage; Humans; Inflammation; Prognosis; Retrospective Studies; Ur

2023
Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis.
    Translational stroke research, 2020, Volume: 11, Issue:5

    Topics: Animals; Cerebral Hemorrhage; Humans; Hypertension; Intracranial Hemorrhage, Hypertensive; MAP Kinas

2020
Relationship of Serum Uric Acid to Hematoma Volume and Prognosis in Patients with Acute Supratentorial Intracerebral Hemorrhage.
    World neurosurgery, 2020, Volume: 143

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cerebral Hemorrhage; Cohort Studies; Female;

2020
Letter to the Editor Regarding "Relationship of Serum Uric Acid to Hematoma Volume and Prognosis in Patients with Acute Supratentorial Intracerebral Hemorrhage".
    World neurosurgery, 2021, Volume: 149

    Topics: Cerebral Hemorrhage; Hematoma; Humans; Prognosis; Uric Acid

2021
In Reply to the Letter to the Editor Regarding "Relationship of Serum Uric Acid to Hematoma Volume and Prognosis in Patients with Acute Supratentorial Intracerebral Hemorrhage".
    World neurosurgery, 2021, Volume: 149

    Topics: Cerebral Hemorrhage; Hematoma; Humans; Prognosis; Uric Acid

2021
Sex-dependent effects of uric acid on cerebral microbleed: a cross-sectional study in the general population.
    European journal of neurology, 2017, Volume: 24, Issue:10

    Topics: Adult; Aged; Cerebral Hemorrhage; Cross-Sectional Studies; Female; Humans; Magnetic Resonance Imagin

2017
Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:3

    Topics: Aged; Biomarkers; Brain Ischemia; Cerebral Hemorrhage; China; Down-Regulation; Female; Humans; Kapla

2014
Retrospective analysis of the predictive effect of routine biochemical results on the prognosis of intracerebral hemorrhage.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Cerebral Hemorrhage; China; Female; Humans; Lipid Met

2011
Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Aged; Cerebral Hemorrhage; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Stroke; Ur

2013
Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants.
    Biology of the neonate, 2003, Volume: 83, Issue:4

    Topics: Apgar Score; Brain Diseases; Cerebral Hemorrhage; Creatinine; Gestational Age; Humans; Infant, Low B

2003
Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke.
    Stroke, 2003, Volume: 34, Issue:8

    Topics: Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Female; Follow-Up Studies; Humans; Ischemi

2003
Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study.
    Stroke, 2006, Volume: 37, Issue:6

    Topics: Aged; Brain Ischemia; Cardiovascular Diseases; Case-Control Studies; Cerebral Hemorrhage; Cohort Stu

2006
Serum uric acid as an independent predictor of early death after acute stroke.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:7

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cerebral Hemorrhage; Cohort Studies; Female; Hospital Morta

2007
Hyponatremia and osmoregulation of vasopressin secretion in patients with intracranial bleeding.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:10

    Topics: Aged; Aged, 80 and over; Arginine Vasopressin; Blood Pressure; Blood Urea Nitrogen; Cerebral Hemorrh

1995
Stroke and alcohol intake in a hospital population. A case-control study.
    Stroke, 1995, Volume: 26, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcoholism; Aspartate Aminotransferases; Biomarker

1995
Relationship of uric acid concentrations and severe intraventricular hemorrhage/leukomalacia in the premature infant.
    The Journal of pediatrics, 1998, Volume: 132, Issue:3 Pt 1

    Topics: Birth Weight; Brain Ischemia; Cerebral Hemorrhage; Gestational Age; Humans; Hypoxia; Infant, Newborn

1998
Hematologic emergencies in children.
    Paediatrician, 1978, Volume: 7, Issue:4-5

    Topics: Acute Disease; Acute Kidney Injury; Adolescent; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Asp

1978
Clinical features and risk factors in stroke in young.
    Acta neurologica Scandinavica, 1979, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Age Factors; Cerebral Hemorrhage; Cerebrovascular Disorders; Child; Child, Presch

1979
Haemorrhage-induced release of noradrenaline, 5-hydroxytryptamine and uric acid in the supraoptic nucleus of the rat, measured by microdialysis.
    Brain research, 1988, Feb-09, Volume: 440, Issue:2

    Topics: Animals; Cerebral Hemorrhage; Dialysis; Dopamine; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphen

1988
Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects.
    Atherosclerosis, 1989, Volume: 79, Issue:2-3

    Topics: Adult; Aged; Cerebral Hemorrhage; Cerebral Infarction; Creatinine; Cysteine; Dipeptides; Female; Hom

1989
Ischemic cerebrovascular disease. The assessment of risk factors.
    Geriatrics, 1968, Volume: 23, Issue:3

    Topics: Adult; Age Factors; Aged; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D

1968