uric acid has been researched along with Cerebral Hemorrhage in 25 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
Excerpt | Relevance | Reference |
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"The relationship between serum uric acid (UA) and the risk of intracerebral hemorrhage (ICH) remains controversial." | 8.98 | Serum uric acid concentrations and risk of intracerebral hemorrhage: A systematic review and meta-analysis. ( Liang, Y; Lin, J; Qu, H; Xu, J; Zhang, X; Zhao, C; Zhao, M; Zhou, Z, 2018) |
" Previous studies have shown that high serum uric acid (SUA) levels are an independent risk factor for hypertension, cardiovascular disease (CVD), and ischemic stroke." | 7.96 | Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis. ( Bai, CX; Chen, JZ; Ge, J; Hui, RT; Li, H; Liu, TL; Song, L; Song, WH; Sun, YY; Wen, HY; Xiao, N; Xu, HC; Zhang, YH, 2020) |
"The relationship between uric acid and stroke prognosis is ambiguous." | 7.80 | Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients. ( Jia, Q; Liu, G; Liu, L; Pu, Y; Wang, C; Wang, Y; Wu, H; Zhao, X, 2014) |
"Unlike experimental studies indicating a neuroprotective property of uric acid, clinical studies have shown that elevated levels of uric acid are associated with a risk of ischemic stroke." | 7.79 | Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke. ( Kim, BJ; Kim, CK; Lee, SH; Ryu, WS, 2013) |
"The prognostic significance of uric acid (UA) levels in acute stroke is unclear, so the objective of this study was to determine the association between levels of serum UA (SUA) and mortality in acute stroke." | 7.74 | Serum uric acid as an independent predictor of early death after acute stroke. ( Athyros, VG; Gossios, T; Kakafika, A; Karagiannis, A; Krikis, N; Mikhailidis, DP; Moschou, I; Savvatianos, S; Sileli, M; Tziomalos, K; Xochellis, M, 2007) |
"The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke." | 7.73 | Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study. ( Bos, MJ; Breteler, MM; Hofman, A; Koudstaal, PJ; Witteman, JC, 2006) |
"The relationship between serum uric acid (UA) and the risk of intracerebral hemorrhage (ICH) remains controversial." | 4.98 | Serum uric acid concentrations and risk of intracerebral hemorrhage: A systematic review and meta-analysis. ( Liang, Y; Lin, J; Qu, H; Xu, J; Zhang, X; Zhao, C; Zhao, M; Zhou, Z, 2018) |
" Previous studies have shown that high serum uric acid (SUA) levels are an independent risk factor for hypertension, cardiovascular disease (CVD), and ischemic stroke." | 3.96 | Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis. ( Bai, CX; Chen, JZ; Ge, J; Hui, RT; Li, H; Liu, TL; Song, L; Song, WH; Sun, YY; Wen, HY; Xiao, N; Xu, HC; Zhang, YH, 2020) |
"Elevated serum uric acid (UA) is known to be associated with stroke." | 3.85 | Sex-dependent effects of uric acid on cerebral microbleed: a cross-sectional study in the general population. ( Jeong, SM; Kim, S; Kim, SH; Kwon, HM; Lee, JE; Lim, JS; Nam, YS; Park, JH; Yoo, TG, 2017) |
"The relationship between uric acid and stroke prognosis is ambiguous." | 3.80 | Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients. ( Jia, Q; Liu, G; Liu, L; Pu, Y; Wang, C; Wang, Y; Wu, H; Zhao, X, 2014) |
"Unlike experimental studies indicating a neuroprotective property of uric acid, clinical studies have shown that elevated levels of uric acid are associated with a risk of ischemic stroke." | 3.79 | Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke. ( Kim, BJ; Kim, CK; Lee, SH; Ryu, WS, 2013) |
"The prognostic significance of uric acid (UA) levels in acute stroke is unclear, so the objective of this study was to determine the association between levels of serum UA (SUA) and mortality in acute stroke." | 3.74 | Serum uric acid as an independent predictor of early death after acute stroke. ( Athyros, VG; Gossios, T; Kakafika, A; Karagiannis, A; Krikis, N; Mikhailidis, DP; Moschou, I; Savvatianos, S; Sileli, M; Tziomalos, K; Xochellis, M, 2007) |
"The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke." | 3.73 | Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study. ( Bos, MJ; Breteler, MM; Hofman, A; Koudstaal, PJ; Witteman, JC, 2006) |
"The purine metabolite hypoxanthine accumulates with hypoxia ischemia and with reperfusion is converted to uric acid (UA)." | 3.70 | Relationship of uric acid concentrations and severe intraventricular hemorrhage/leukomalacia in the premature infant. ( Perlman, JM; Risser, R, 1998) |
"Radiological markers for cerebral small vessel disease (SVD) may have different biological underpinnings in their development." | 1.91 | Classification of white matter lesions and characteristics of small vessel disease markers. ( Hwang, SA; Jung, KH; Kim, S; Lee, EJ; Lee, WJ; Park, KI; Salat, DH, 2023) |
"Uric acid levels were related to serum creatinine (p < 0." | 1.32 | Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants. ( Rozycki, HJ; Sysyn, GD, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (24.00) | 18.7374 |
1990's | 3 (12.00) | 18.2507 |
2000's | 4 (16.00) | 29.6817 |
2010's | 5 (20.00) | 24.3611 |
2020's | 7 (28.00) | 2.80 |
Authors | Studies |
---|---|
Wang, D | 1 |
Wang, Y | 5 |
Xu, D | 1 |
Zhou, G | 1 |
He, S | 1 |
Park, KI | 1 |
Jung, KH | 1 |
Lee, EJ | 1 |
Lee, WJ | 1 |
Hwang, SA | 1 |
Kim, S | 2 |
Salat, DH | 1 |
Wang, Q | 1 |
Li, S | 1 |
Sun, M | 1 |
Ma, J | 1 |
Sun, J | 1 |
Fan, M | 1 |
Xiao, N | 1 |
Liu, TL | 1 |
Li, H | 1 |
Xu, HC | 1 |
Ge, J | 1 |
Wen, HY | 1 |
Bai, CX | 1 |
Song, L | 1 |
Sun, YY | 1 |
Zhang, YH | 1 |
Hui, RT | 1 |
Song, WH | 1 |
Chen, JZ | 1 |
Huang, H | 2 |
Huang, G | 2 |
Gu, J | 1 |
Chen, K | 2 |
Huang, Y | 1 |
Xu, H | 2 |
Jeong, SM | 1 |
Yoo, TG | 1 |
Nam, YS | 1 |
Kim, SH | 1 |
Lee, JE | 1 |
Lim, JS | 1 |
Kwon, HM | 1 |
Park, JH | 1 |
Zhou, Z | 1 |
Liang, Y | 1 |
Lin, J | 1 |
Zhang, X | 1 |
Qu, H | 1 |
Xu, J | 1 |
Zhao, C | 1 |
Zhao, M | 1 |
Wu, H | 1 |
Jia, Q | 1 |
Liu, G | 1 |
Liu, L | 1 |
Pu, Y | 1 |
Zhao, X | 1 |
Wang, C | 1 |
Chen, H | 1 |
Li, F | 1 |
Wang, X | 1 |
Kong, Y | 1 |
Ryu, WS | 1 |
Kim, CK | 1 |
Kim, BJ | 1 |
Lee, SH | 1 |
Sysyn, GD | 1 |
Rozycki, HJ | 1 |
Weir, CJ | 1 |
Muir, SW | 1 |
Walters, MR | 1 |
Lees, KR | 1 |
Bos, MJ | 1 |
Koudstaal, PJ | 1 |
Hofman, A | 1 |
Witteman, JC | 1 |
Breteler, MM | 1 |
Karagiannis, A | 1 |
Mikhailidis, DP | 1 |
Tziomalos, K | 1 |
Sileli, M | 1 |
Savvatianos, S | 1 |
Kakafika, A | 1 |
Gossios, T | 1 |
Krikis, N | 1 |
Moschou, I | 1 |
Xochellis, M | 1 |
Athyros, VG | 1 |
Kamoi, K | 1 |
Toyama, M | 1 |
Ishibashi, M | 1 |
Yamaji, T | 1 |
Beghi, E | 1 |
Boglium, G | 1 |
Cosso, P | 1 |
Fiorelli, G | 1 |
Lorini, C | 1 |
Mandelli, M | 1 |
Bellini, A | 1 |
Perlman, JM | 1 |
Risser, R | 1 |
Ekert, H | 1 |
Waters, KD | 1 |
Chopra, JS | 1 |
Prabhakar, S | 1 |
Mertz, DP | 1 |
Kendrick, KM | 1 |
Leng, G | 1 |
Araki, A | 1 |
Sako, Y | 1 |
Fukushima, Y | 1 |
Matsumoto, M | 1 |
Asada, T | 1 |
Kita, T | 1 |
Gertler, MM | 1 |
Rusk, HA | 1 |
Whiter, HH | 1 |
Leetma, HE | 1 |
Ehrenkranz, M | 1 |
2 reviews available for uric acid and Cerebral Hemorrhage
Article | Year |
---|---|
Serum uric acid concentrations and risk of intracerebral hemorrhage: A systematic review and meta-analysis.
Topics: Age Factors; Aged; Biomarkers; Cerebral Hemorrhage; Comorbidity; Female; Humans; Hyperuricemia; Male | 2018 |
[Significance of physical activity in the prevention of degenerative heart and vascular diseases?].
Topics: Adult; Age Factors; Arteriosclerosis; Body Weight; Cerebral Hemorrhage; Cerebrovascular Disorders; C | 1976 |
23 other studies available for uric acid and Cerebral Hemorrhage
Article | Year |
---|---|
Relationship between uric acid and cerebral amyloid angiopathy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cerebral Amyloid Angiopathy; Cerebral Hemo | 2023 |
Classification of white matter lesions and characteristics of small vessel disease markers.
Topics: Aged; Brain; Cerebral Hemorrhage; Cerebral Small Vessel Diseases; Diabetes Mellitus; Humans; Magneti | 2023 |
Systemic immune-inflammation index may predict the acute kidney injury and prognosis in patients with spontaneous cerebral hemorrhage undergoing craniotomy: a single-center retrospective study.
Topics: Acute Kidney Injury; Cerebral Hemorrhage; Humans; Inflammation; Prognosis; Retrospective Studies; Ur | 2023 |
Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis.
Topics: Animals; Cerebral Hemorrhage; Humans; Hypertension; Intracranial Hemorrhage, Hypertensive; MAP Kinas | 2020 |
Relationship of Serum Uric Acid to Hematoma Volume and Prognosis in Patients with Acute Supratentorial Intracerebral Hemorrhage.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Cerebral Hemorrhage; Cohort Studies; Female; | 2020 |
Letter to the Editor Regarding "Relationship of Serum Uric Acid to Hematoma Volume and Prognosis in Patients with Acute Supratentorial Intracerebral Hemorrhage".
Topics: Cerebral Hemorrhage; Hematoma; Humans; Prognosis; Uric Acid | 2021 |
In Reply to the Letter to the Editor Regarding "Relationship of Serum Uric Acid to Hematoma Volume and Prognosis in Patients with Acute Supratentorial Intracerebral Hemorrhage".
Topics: Cerebral Hemorrhage; Hematoma; Humans; Prognosis; Uric Acid | 2021 |
Sex-dependent effects of uric acid on cerebral microbleed: a cross-sectional study in the general population.
Topics: Adult; Aged; Cerebral Hemorrhage; Cross-Sectional Studies; Female; Humans; Magnetic Resonance Imagin | 2017 |
Decreased uric acid levels correlate with poor outcomes in acute ischemic stroke patients, but not in cerebral hemorrhage patients.
Topics: Aged; Biomarkers; Brain Ischemia; Cerebral Hemorrhage; China; Down-Regulation; Female; Humans; Kapla | 2014 |
Retrospective analysis of the predictive effect of routine biochemical results on the prognosis of intracerebral hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Cerebral Hemorrhage; China; Female; Humans; Lipid Met | 2011 |
Serum uric acid levels and cerebral microbleeds in patients with acute ischemic stroke.
Topics: Aged; Cerebral Hemorrhage; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Stroke; Ur | 2013 |
Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants.
Topics: Apgar Score; Brain Diseases; Cerebral Hemorrhage; Creatinine; Gestational Age; Humans; Infant, Low B | 2003 |
Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke.
Topics: Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Female; Follow-Up Studies; Humans; Ischemi | 2003 |
Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study.
Topics: Aged; Brain Ischemia; Cardiovascular Diseases; Case-Control Studies; Cerebral Hemorrhage; Cohort Stu | 2006 |
Serum uric acid as an independent predictor of early death after acute stroke.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Cerebral Hemorrhage; Cohort Studies; Female; Hospital Morta | 2007 |
Hyponatremia and osmoregulation of vasopressin secretion in patients with intracranial bleeding.
Topics: Aged; Aged, 80 and over; Arginine Vasopressin; Blood Pressure; Blood Urea Nitrogen; Cerebral Hemorrh | 1995 |
Stroke and alcohol intake in a hospital population. A case-control study.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcoholism; Aspartate Aminotransferases; Biomarker | 1995 |
Relationship of uric acid concentrations and severe intraventricular hemorrhage/leukomalacia in the premature infant.
Topics: Birth Weight; Brain Ischemia; Cerebral Hemorrhage; Gestational Age; Humans; Hypoxia; Infant, Newborn | 1998 |
Hematologic emergencies in children.
Topics: Acute Disease; Acute Kidney Injury; Adolescent; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Asp | 1978 |
Clinical features and risk factors in stroke in young.
Topics: Adolescent; Adult; Age Factors; Cerebral Hemorrhage; Cerebrovascular Disorders; Child; Child, Presch | 1979 |
Haemorrhage-induced release of noradrenaline, 5-hydroxytryptamine and uric acid in the supraoptic nucleus of the rat, measured by microdialysis.
Topics: Animals; Cerebral Hemorrhage; Dialysis; Dopamine; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphen | 1988 |
Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects.
Topics: Adult; Aged; Cerebral Hemorrhage; Cerebral Infarction; Creatinine; Cysteine; Dipeptides; Female; Hom | 1989 |
Ischemic cerebrovascular disease. The assessment of risk factors.
Topics: Adult; Age Factors; Aged; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary D | 1968 |