uric acid has been researched along with Cataract in 17 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the involvement of uric acid (UA) in the pathogenesis of posterior subcapsular cataract (PSC)." | 7.96 | Elevated level of uric acid in aqueous humour is associated with posterior subcapsular cataract in human lens. ( Chan, SO; Chen, YL; Chu, WK; Lin, HL; Niu, YY; Pang, CP; Qin, YJ; Xie, WJ; Zhang, HY; Zhang, YQ, 2020) |
| "High-performance liquid chromatography measured levels of uric acid and xanthine in aqueous humor samples of patients with retinoblastoma, melanoma, Coats' disease, adult cataract, and congenital cataract." | 7.70 | Uric acid in the aqueous humor and tears of retinoblastoma patients. ( Abramson, DH; Gamache, PH; Mendelsohn, ME; Senft, S; Servodidio, CA, 1998) |
| "Uric acid was marked by indirect method with uricase." | 6.68 | [Level of uric acid in aqueous humor of patients with cataract]. ( Kałuzny, J; Kałuzny, JJ; Raukuć, D, 1996) |
| "Uric acid was marked by indirect method with uricase." | 6.68 | [Uric acid level in aqueous humor of patients with cataract]. ( Kałuzny, J; Kałuzny, JJ; Raukuć, D, 1996) |
| "Uric acid, which is an endogenous antioxidant was statistically significantly decreased in the urine and plasma of SDZ ICT 322 VE/SeD treated rats." | 5.30 | Enhancement of SDZ ICT 322-induced cataracts and skin changes in rats following vitamin E- and selenium-deficient diet. ( Cordier, A; Längle, UW; Wolf, A, 1997) |
| "To examine the involvement of uric acid (UA) in the pathogenesis of posterior subcapsular cataract (PSC)." | 3.96 | Elevated level of uric acid in aqueous humour is associated with posterior subcapsular cataract in human lens. ( Chan, SO; Chen, YL; Chu, WK; Lin, HL; Niu, YY; Pang, CP; Qin, YJ; Xie, WJ; Zhang, HY; Zhang, YQ, 2020) |
| "The aim of this investigation was to assess and compare levels of uric acid in human tear fluid, aqueous humour and serum in cataract patients in order to obtain information about uric acid-dependent antioxidative status." | 3.75 | Determination of uric acid concentrations in human tear fluid, aqueous humour and serum. ( Faschinger, C; Horwath-Winter, J; Kirchengast, S; Meinitzer, A; Schmut, O; Wachswender, C, 2009) |
| "The levels of the two major primate UV filters, 3-hydroxykynurenine glucoside (3OHKG) and 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid glucoside (AHBG), in cataract lenses were markedly decreased compared with levels in normal lenses." | 3.72 | Lenticular levels of amino acids and free UV filters differ significantly between normals and cataract patients. ( Jamie, JF; Streete, IM; Truscott, RJ, 2004) |
| "High-performance liquid chromatography measured levels of uric acid and xanthine in aqueous humor samples of patients with retinoblastoma, melanoma, Coats' disease, adult cataract, and congenital cataract." | 3.70 | Uric acid in the aqueous humor and tears of retinoblastoma patients. ( Abramson, DH; Gamache, PH; Mendelsohn, ME; Senft, S; Servodidio, CA, 1998) |
| "The concentration of the free aromatic amino acids tryptophan and tyrosine, the antioxidant uric acid and some unidentified compounds have been determined in the water-soluble extracts of parts from clear and nuclear-cataractous human lenses." | 3.67 | Distribution of aromatic and fluorescent compounds within single human lenses. ( Bessems, GJ; Hoenders, HJ, 1987) |
| "Uric acid was marked by indirect method with uricase." | 2.68 | [Level of uric acid in aqueous humor of patients with cataract]. ( Kałuzny, J; Kałuzny, JJ; Raukuć, D, 1996) |
| "Uric acid was marked by indirect method with uricase." | 2.68 | [Uric acid level in aqueous humor of patients with cataract]. ( Kałuzny, J; Kałuzny, JJ; Raukuć, D, 1996) |
| "Uric acid, which is an endogenous antioxidant was statistically significantly decreased in the urine and plasma of SDZ ICT 322 VE/SeD treated rats." | 1.30 | Enhancement of SDZ ICT 322-induced cataracts and skin changes in rats following vitamin E- and selenium-deficient diet. ( Cordier, A; Längle, UW; Wolf, A, 1997) |
| "Lens opacities were associated with lower levels of riboflavin, vitamin E, iron, and protein nutritional status." | 1.29 | Biochemical factors in the lens opacities. Case-control study. The Lens Opacities Case-Control Study Group. ( Ansari, N; Chylack, LT; Hyman, L; Leske, MC; Milton, RC; Sperduto, R; Srivastava, S; Underwood, B; Wu, SY, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bouchemi, M | 1 |
| Soualmia, H | 1 |
| Midani, F | 1 |
| El Afrit, MA | 1 |
| El Asmi, M | 1 |
| Feki, M | 1 |
| Qin, YJ | 1 |
| Chan, SO | 1 |
| Lin, HL | 1 |
| Zhang, YQ | 1 |
| Chen, YL | 1 |
| Niu, YY | 1 |
| Xie, WJ | 1 |
| Chu, WK | 1 |
| Pang, CP | 1 |
| Zhang, HY | 1 |
| Horwath-Winter, J | 1 |
| Kirchengast, S | 1 |
| Meinitzer, A | 1 |
| Wachswender, C | 1 |
| Faschinger, C | 1 |
| Schmut, O | 1 |
| Streete, IM | 1 |
| Jamie, JF | 1 |
| Truscott, RJ | 1 |
| Leske, MC | 1 |
| Wu, SY | 1 |
| Hyman, L | 1 |
| Sperduto, R | 1 |
| Underwood, B | 1 |
| Chylack, LT | 1 |
| Milton, RC | 1 |
| Srivastava, S | 1 |
| Ansari, N | 1 |
| Kałuzny, J | 2 |
| Kałuzny, JJ | 2 |
| Raukuć, D | 2 |
| Längle, UW | 1 |
| Wolf, A | 1 |
| Cordier, A | 1 |
| Richer, SP | 1 |
| Rose, RC | 1 |
| Mendelsohn, ME | 1 |
| Abramson, DH | 1 |
| Senft, S | 1 |
| Servodidio, CA | 1 |
| Gamache, PH | 1 |
| Aksoy, H | 1 |
| Keles, S | 1 |
| Koçer, I | 1 |
| Akçay, F | 1 |
| Bässler, KH | 1 |
| Szczypka, M | 1 |
| Gajewski, J | 1 |
| Laskowska-Klita, T | 1 |
| Zbieg-Sendecka, E | 1 |
| Brás, A | 1 |
| Monteiro, C | 1 |
| Rueff, J | 1 |
| Bessems, GJ | 1 |
| Hoenders, HJ | 1 |
| Paulson, GW | 1 |
| Son, CD | 1 |
| Nance, WE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Laser Species and Ocular Antioxidant Activity on Postoperative Inflammation and Visual Prognosis in Patients Undergoing Ophthalmic Surgery - a Comparative Study[NCT05905237] | 1,000 participants (Anticipated) | Observational | 2022-07-12 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for uric acid and Cataract
| Article | Year |
|---|---|
[Level of uric acid in aqueous humor of patients with cataract].
Topics: Adult; Aged; Aged, 80 and over; Aqueous Humor; Cataract; Female; Humans; Male; Middle Aged; Uric Aci | 1996 |
[Uric acid level in aqueous humor of patients with cataract].
Topics: Adult; Aged; Aged, 80 and over; Aqueous Humor; Cataract; Female; Humans; Male; Middle Aged; Uric Aci | 1996 |
15 other studies available for uric acid and Cataract
| Article | Year |
|---|---|
Impaired nitric oxide production in patients with primary open-angle glaucoma.
Topics: Aqueous Humor; Blood Chemical Analysis; Case-Control Studies; Cataract; Female; Glaucoma, Open-Angle | 2020 |
Elevated level of uric acid in aqueous humour is associated with posterior subcapsular cataract in human lens.
Topics: Aqueous Humor; Cataract; Humans; Lens, Crystalline; Retrospective Studies; Uric Acid | 2020 |
Determination of uric acid concentrations in human tear fluid, aqueous humour and serum.
Topics: Aged; Aged, 80 and over; Antioxidants; Aqueous Humor; Cataract; Chromatography, High Pressure Liquid | 2009 |
Lenticular levels of amino acids and free UV filters differ significantly between normals and cataract patients.
Topics: Adult; Aged; Aged, 80 and over; Cataract; Chromatography, High Pressure Liquid; Glucosides; Humans; | 2004 |
Biochemical factors in the lens opacities. Case-control study. The Lens Opacities Case-Control Study Group.
Topics: Adult; Aged; Amino Acids; Case-Control Studies; Cataract; Erythrocytes; Female; Glutathione Reductas | 1995 |
Enhancement of SDZ ICT 322-induced cataracts and skin changes in rats following vitamin E- and selenium-deficient diet.
Topics: Animals; Body Weight; Cataract; Eating; Indoles; Male; Oxidative Stress; Rats; Rats, Wistar; Seleniu | 1997 |
Water soluble antioxidants in mammalian aqueous humor: interaction with UV B and hydrogen peroxide.
Topics: Aged; Analysis of Variance; Animals; Antioxidants; Aqueous Humor; Ascorbic Acid; Cataract; Chromatog | 1998 |
Uric acid in the aqueous humor and tears of retinoblastoma patients.
Topics: Adult; Aqueous Humor; Cataract; Chromatography, High Pressure Liquid; Humans; Infant; Melanoma; Reti | 1998 |
Diabetic cataract and the total antioxidant status in aqueous humor.
Topics: Aged; Antioxidants; Aqueous Humor; Case-Control Studies; Cataract; Diabetes Mellitus, Type 2; Humans | 2001 |
Absorption, metabolism, and tolerance of polyol sugar substitutes.
Topics: Absorption; Cataract; Chemical Phenomena; Chemistry; Diarrhea; Glucuronates; Humans; Intestinal Abso | 1978 |
Risk factors for age-related cortical, nuclear, and posterior subcapsular cataracts. The Italian-American Cataract Study Group.
Topics: Adult; Age Factors; Aged; Case-Control Studies; Cataract; Confounding Factors, Epidemiologic; Cortis | 1991 |
Red blood cells and serum antioxidant defense systems of galactosaemic children.
Topics: Antioxidants; Cataract; Ceruloplasmin; Child; Child, Preschool; Erythrocytes; Galactosemias; Humans; | 1990 |
Oxidative stress in trisomy 21. A possible role in cataractogenesis.
Topics: Adolescent; Adult; Ascorbic Acid; Cataract; Child; Child, Preschool; Down Syndrome; Erythrocytes; Fr | 1989 |
Distribution of aromatic and fluorescent compounds within single human lenses.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cataract; Chromatography, High Pressure Liquid; Fluorescence; | 1987 |
Neurologic aspects of typical and atypical Down's syndrome.
Topics: Cataract; Chromosome Aberrations; Down Syndrome; Gait; Humans; Hydroxyindoleacetic Acid; Intelligenc | 1969 |