Page last updated: 2024-10-20

uric acid and Carotid Stenosis

uric acid has been researched along with Carotid Stenosis in 16 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)

Research Excerpts

ExcerptRelevanceReference
"Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with atherosclerosis, respectively."8.12Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. ( Dong, H; Hu, X; Li, G; Li, W; Liu, J; Wang, C; Zhou, Y, 2022)
"The role of serum uric acid in ischemic stroke is controversial."7.91Association between serum uric acid and carotid disease in patients with atherosclerotic acute ischemic stroke. ( Arévalo-Lorido, JC; Carretero-Gómez, J; Robles Pérez-Monteoliva, NR, 2019)
"Uric acid is a molecule that is known to act as a natural antioxidant in acute oxidative stress conditions such as acute ischemic stroke (AIS)."7.88Can high uric acid levels be an independent risk factor for acute ischemic stroke due to large-artery atherosclerosis? ( Acar, AB; Acar, T; Gül, SS; Güzey Aras, Y, 2018)
"Between 2009 and 2012, we conducted a study among 406 consecutive first-ever ischemic stroke patients to assess the relationship between uric acid and carotid artery."7.80Association of uric acid and carotid artery disease in patients with ischemic stroke. ( Kabaroglu, C; Karaman, B; Kumral, E; Orman, M, 2014)
"We aimed to investigate whether elevated serum uric acid concentrations are associated with higher risk of metabolic syndrome (MetS) and carotid atherosclerosis in patients with type 2 diabetes."7.77Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. ( Chen, L; He, M; Hu, R; Huang, Y; Li, Q; Lu, B; Qu, S; Tao, X; Wen, J; Yang, Z; Ye, Z; Zhang, W; Zhang, Z, 2011)
" The keywords used to retrieve the literature were carotid intima thickness, intima-media thickness, carotid atherosclerosis, carotid stenosis, carotid artery, uric acid, blood uric acid, and hyperuricaemia."5.12Meta-analysis of the correlation between serum uric acid level and carotid intima-media thickness. ( Huang, W; Li, L; Ma, M; Mao, M; Peng, B; Wang, H; Wang, L; Zhong, X, 2021)
"Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with atherosclerosis, respectively."4.12Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. ( Dong, H; Hu, X; Li, G; Li, W; Liu, J; Wang, C; Zhou, Y, 2022)
"The role of serum uric acid in ischemic stroke is controversial."3.91Association between serum uric acid and carotid disease in patients with atherosclerotic acute ischemic stroke. ( Arévalo-Lorido, JC; Carretero-Gómez, J; Robles Pérez-Monteoliva, NR, 2019)
"Uric acid is a molecule that is known to act as a natural antioxidant in acute oxidative stress conditions such as acute ischemic stroke (AIS)."3.88Can high uric acid levels be an independent risk factor for acute ischemic stroke due to large-artery atherosclerosis? ( Acar, AB; Acar, T; Gül, SS; Güzey Aras, Y, 2018)
"Between 2009 and 2012, we conducted a study among 406 consecutive first-ever ischemic stroke patients to assess the relationship between uric acid and carotid artery."3.80Association of uric acid and carotid artery disease in patients with ischemic stroke. ( Kabaroglu, C; Karaman, B; Kumral, E; Orman, M, 2014)
"We aimed to investigate whether elevated serum uric acid concentrations are associated with higher risk of metabolic syndrome (MetS) and carotid atherosclerosis in patients with type 2 diabetes."3.77Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. ( Chen, L; He, M; Hu, R; Huang, Y; Li, Q; Lu, B; Qu, S; Tao, X; Wen, J; Yang, Z; Ye, Z; Zhang, W; Zhang, Z, 2011)
"Hyperuricemia is closely associated with cardiovascular disease (CVD)."1.56Association between serum level of urate and subclinical atherosclerosis: results from the SCAPIS Pilot. ( Angerås, O; Bergström, G; Dehlin, M; Drivelegka, P; Forsblad-d'Elia, H; Jacobsson, LTH; Schmidt, C, 2020)
" The association of SUA with PLQ increased with increasing SUA levels, demonstrating a dose-response relation for men [OR 1."1.35Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study. ( Ellison, RC; Felson, DT; Hunt, S; Neogi, T; Terkeltaub, R; Zhang, Y, 2009)
"This study was carried out on carotid artery plaque and plasma of 50 patients."1.33Purine catabolism in advanced carotid artery plaque. ( Ciari, I; Felici, C; Giubbolini, M; Marinello, E; Porcelli, B; Setacci, C; Terzuoli, L, 2006)
"The uric acid level was positively correlated in both sexes with a variety of health-related factors, most notably body mass index, creatinine, triglycerides, diuretic use, alcohol intake, hypertension, diabetes, and insulin levels."1.29Correlates of uric acid and its association with asymptomatic carotid atherosclerosis: the ARIC Study. Atherosclerosis Risk in Communities. ( Eckfeldt, JH; Folsom, AR; Iribarren, C; McGovern, PG; Nieto, FJ, 1996)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's2 (12.50)29.6817
2010's6 (37.50)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Tan, Y1
Qing, J1
Wu, G1
Li, X1
Guo, F1
Wang, Y2
Wang, L2
Li, M1
Hu, X1
Liu, J1
Li, W1
Wang, C1
Li, G1
Zhou, Y2
Dong, H1
Xi, J3
Men, S3
Nan, J3
Yang, Q3
Dong, J3
Drivelegka, P1
Forsblad-d'Elia, H1
Angerås, O1
Bergström, G1
Schmidt, C1
Jacobsson, LTH1
Dehlin, M1
Ma, M1
Huang, W1
Zhong, X1
Li, L1
Wang, H1
Peng, B1
Mao, M1
Acar, T1
Güzey Aras, Y1
Gül, SS1
Acar, AB1
Yang, X1
Lv, H1
Hidru, TH1
Wu, J1
Liu, H1
Liu, K1
Xia, Y1
Jiang, Y1
Arévalo-Lorido, JC1
Carretero-Gómez, J1
Robles Pérez-Monteoliva, NR1
Kumral, E1
Karaman, B1
Orman, M1
Kabaroglu, C1
Neogi, T1
Ellison, RC1
Hunt, S1
Terkeltaub, R1
Felson, DT1
Zhang, Y1
Kim, JH2
Kim, SY1
Jung, ES1
Jung, SW1
Koo, JS1
Yeon, JE1
Kwon, SY1
Lee, SW1
Byun, KS1
Lee, CH1
Li, Q1
Yang, Z1
Lu, B1
Wen, J1
Ye, Z1
Chen, L1
He, M1
Tao, X1
Zhang, W1
Huang, Y1
Zhang, Z1
Qu, S1
Hu, R1
Felici, C1
Ciari, I1
Terzuoli, L1
Porcelli, B1
Setacci, C1
Giubbolini, M1
Marinello, E1
Iribarren, C1
Folsom, AR1
Eckfeldt, JH1
McGovern, PG1
Nieto, FJ1
Patetsios, P1
Rodino, W1
Wisselink, W1
Bryan, D1
Kirwin, JD1
Panetta, TF1
Saito, D1
Shiraki, T1
Oka, T1
Kajiyama, A1
Doi, M1
Masaka, T1

Reviews

1 review available for uric acid and Carotid Stenosis

ArticleYear
Meta-analysis of the correlation between serum uric acid level and carotid intima-media thickness.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Carotid Stenosis; Humans;

2021

Other Studies

15 other studies available for uric acid and Carotid Stenosis

ArticleYear
Correlation between serum uric acid levels and carotid plaque neovascularisation assessed by contrast-enhanced ultrasound.
    Clinical radiology, 2021, Volume: 76, Issue:12

    Topics: Aged; Carotid Stenosis; Cohort Studies; Female; Humans; Male; Middle Aged; Neovascularization, Patho

2021
Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2022, Volume: 32, Issue:7

    Topics: Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Carotid Stenosis; Choleste

2022
The blood monocyte to high density lipoprotein cholesterol ratio (MHR) is a possible marker of carotid artery plaque.
    Lipids in health and disease, 2022, Dec-03, Volume: 21, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Carotid Stenosis; Cholesterol, HDL; Creatinine; Glycated Hemoglobin;

2022
The blood monocyte to high density lipoprotein cholesterol ratio (MHR) is a possible marker of carotid artery plaque.
    Lipids in health and disease, 2022, Dec-03, Volume: 21, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Carotid Stenosis; Cholesterol, HDL; Creatinine; Glycated Hemoglobin;

2022
The blood monocyte to high density lipoprotein cholesterol ratio (MHR) is a possible marker of carotid artery plaque.
    Lipids in health and disease, 2022, Dec-03, Volume: 21, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Carotid Stenosis; Cholesterol, HDL; Creatinine; Glycated Hemoglobin;

2022
The blood monocyte to high density lipoprotein cholesterol ratio (MHR) is a possible marker of carotid artery plaque.
    Lipids in health and disease, 2022, Dec-03, Volume: 21, Issue:1

    Topics: Biomarkers; C-Reactive Protein; Carotid Stenosis; Cholesterol, HDL; Creatinine; Glycated Hemoglobin;

2022
Association between serum level of urate and subclinical atherosclerosis: results from the SCAPIS Pilot.
    Arthritis research & therapy, 2020, 02-22, Volume: 22, Issue:1

    Topics: Carotid Intima-Media Thickness; Carotid Stenosis; Cohort Studies; Coronary Artery Disease; Female; H

2020
Can high uric acid levels be an independent risk factor for acute ischemic stroke due to large-artery atherosclerosis?
    Ideggyogyaszati szemle, 2018, Jul-30, Volume: 71, Issue:7-08

    Topics: Atherosclerosis; Bilirubin; Biomarkers; Brain Ischemia; Carotid Intima-Media Thickness; Carotid Sten

2018
Relation of serum uric acid to asymptomatic proximal extracranial artery stenosis in a middle-aged Chinese population: a community-based cross-sectional study.
    BMJ open, 2018, 08-23, Volume: 8, Issue:8

    Topics: Adult; Asian People; Asymptomatic Diseases; Biomarkers; Carotid Stenosis; China; Cohort Studies; Cro

2018
Association between serum uric acid and carotid disease in patients with atherosclerotic acute ischemic stroke.
    Vascular, 2019, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Carotid Intima-Media Thickness; Carotid Stenosi

2019
Association of uric acid and carotid artery disease in patients with ischemic stroke.
    Acta neurologica Scandinavica, 2014, Volume: 130, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carotid Intima-Media Thickness; Carotid Stenosis; Female; Humans; Hy

2014
Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study.
    The Journal of rheumatology, 2009, Volume: 36, Issue:2

    Topics: Adult; Aged; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Carotid Stenosis; Cohort Studies

2009
Carotid intima-media thickness is increased not only in non-alcoholic fatty liver disease patients but also in alcoholic fatty liver patients.
    Digestion, 2011, Volume: 84, Issue:2

    Topics: Adult; Alanine Transaminase; Alcohol Drinking; Analysis of Variance; Aspartate Aminotransferases; Bi

2011
Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes.
    Cardiovascular diabetology, 2011, Aug-04, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Carotid Steno

2011
Purine catabolism in advanced carotid artery plaque.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:9-11

    Topics: Aged; Aged, 80 and over; Allantoin; Allopurinol; Carotid Stenosis; Chemistry, Clinical; Female; Free

2006
Correlates of uric acid and its association with asymptomatic carotid atherosclerosis: the ARIC Study. Atherosclerosis Risk in Communities.
    Annals of epidemiology, 1996, Volume: 6, Issue:4

    Topics: Age Distribution; Analysis of Variance; Arteriosclerosis; Black People; Carotid Stenosis; Cohort Stu

1996
Identification of uric acid in aortic aneurysms and atherosclerotic artery.
    Annals of the New York Academy of Sciences, 1996, Nov-18, Volume: 800

    Topics: Adult; Aged; Aortic Aneurysm, Abdominal; Arteriosclerosis; Carotid Stenosis; Chromatography, High Pr

1996
Morphologic correlation between atherosclerotic lesions of the carotid and coronary arteries in patients with angina pectoris.
    Japanese circulation journal, 1999, Volume: 63, Issue:7

    Topics: Aged; Angina Pectoris; Arteriosclerosis; Blood Pressure; C-Reactive Protein; Carotid Artery Diseases

1999