uric acid has been researched along with Cardiotoxicity in 2 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Histopathological examination of the heart, and biochemical examinations for heart function (creatine phosphokinase (CPK), lactate dehydrogenase (LDH), and aspartate aminotransferase (AST)), inflammation (tumor necrosis factor-alpha (TNF-α) and interleukin 10 (IL-10)), oxidative stress (malondialdehyde (MDA), glutathione (GSH), superoxide dismutase (SOD), catalase, nitric oxide (NO), and uric acid), kidney function (urea and creatinine), and minerals (calcium, phosphorus, sodium, and potassium) were carried out." | 4.31 | Glycine protects against doxorubicin-induced heart toxicity in mice. ( El-Ablack, FZ; Saad, EA; Shosha, MI, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shosha, MI | 1 |
| El-Ablack, FZ | 1 |
| Saad, EA | 1 |
| Tanaka, Y | 1 |
| Nagoshi, T | 1 |
| Yoshii, A | 1 |
| Oi, Y | 1 |
| Takahashi, H | 1 |
| Kimura, H | 1 |
| Ito, K | 1 |
| Kashiwagi, Y | 1 |
| Tanaka, TD | 1 |
| Yoshimura, M | 1 |
2 other studies available for uric acid and Cardiotoxicity
| Article | Year |
|---|---|
Glycine protects against doxorubicin-induced heart toxicity in mice.
Topics: Animals; Antioxidants; Cardiomyopathies; Cardiotoxicity; Catalase; Doxorubicin; Glutathione; Inflamm | 2023 |
Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice.
Topics: Animals; Cardiotoxicity; Doxorubicin; Febuxostat; Mice; Uric Acid; Xanthine Oxidase | 2021 |