Page last updated: 2024-10-20

uric acid and Cardiac Remodeling, Ventricular

uric acid has been researched along with Cardiac Remodeling, Ventricular in 13 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Our aim in this study was to investigate the changes of serum high-sensitive C-reactive protein (hs-CRP) and uric acid (UA), and evaluate the synergistic effect of amlodipine and atorvastatin on blood pressure and left ventricular remodeling in hypertensive patients with primary hypercholesterolemia."9.13Synergistic effect of amlodipine and atorvastatin on blood pressure, left ventricular remodeling, and C-reactive protein in hypertensive patients with primary hypercholesterolemia. ( Chen, YD; Ge, CJ; Hu, SJ; Ji, Y; Lu, SZ; Wu, XF, 2008)
" This study was designed to evaluate the influences of long-term xanthine oxidase inhibitor (febuxostat) prescription on left ventricular hypertrophy (LVH), left ventricular (LV) diastolic function, and new-onset heart failure with preserved ejection fraction (HFpEF) in these patients."7.96Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia. ( Gu, J; Lin, H; Pan, JA; Wang, CQ; Zhang, JF, 2020)
"Uric acid and gamma-glutamyl transferase are prognostic indicators in chronic heart failure."7.80Uric acid and gamma-glutamyl transferase activity are associated with left ventricular remodeling indices in patients with chronic heart failure. ( Jelic, S; Markovic, O; Memon, L; Pekmezovic, T; Pljesa-Ercegovac, M; Radic, T; Radovanovic, S; Savic-Radojevic, A; Simic, D; Simic, T, 2014)
" Previous studies using uric acid-lowering drugs in normouricemic animals are not suitable to answer the effect of hyperuricemia on ventricular remodeling after myocardial infarction."7.77Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia. ( Chen, CC; Hsu, YJ; Lee, TM, 2011)
"Our aim in this study was to investigate the changes of serum high-sensitive C-reactive protein (hs-CRP) and uric acid (UA), and evaluate the synergistic effect of amlodipine and atorvastatin on blood pressure and left ventricular remodeling in hypertensive patients with primary hypercholesterolemia."5.13Synergistic effect of amlodipine and atorvastatin on blood pressure, left ventricular remodeling, and C-reactive protein in hypertensive patients with primary hypercholesterolemia. ( Chen, YD; Ge, CJ; Hu, SJ; Ji, Y; Lu, SZ; Wu, XF, 2008)
" This study was designed to evaluate the influences of long-term xanthine oxidase inhibitor (febuxostat) prescription on left ventricular hypertrophy (LVH), left ventricular (LV) diastolic function, and new-onset heart failure with preserved ejection fraction (HFpEF) in these patients."3.96Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia. ( Gu, J; Lin, H; Pan, JA; Wang, CQ; Zhang, JF, 2020)
"Serum uric acid levels were not significantly different in the asymptomatic hyperuricaemia, gouty arthritis without tophi and gouty tophi groups."3.80The effects of gout on left atrial volume remodelling: a prospective echocardiographic study. ( Chang, PJ; Chang, ST; Chen, MC; Chung, CM; Hsiao, JF; Lin, CL; Lin, JC; Pan, KL, 2014)
"Uric acid and gamma-glutamyl transferase are prognostic indicators in chronic heart failure."3.80Uric acid and gamma-glutamyl transferase activity are associated with left ventricular remodeling indices in patients with chronic heart failure. ( Jelic, S; Markovic, O; Memon, L; Pekmezovic, T; Pljesa-Ercegovac, M; Radic, T; Radovanovic, S; Savic-Radojevic, A; Simic, D; Simic, T, 2014)
" Previous studies using uric acid-lowering drugs in normouricemic animals are not suitable to answer the effect of hyperuricemia on ventricular remodeling after myocardial infarction."3.77Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia. ( Chen, CC; Hsu, YJ; Lee, TM, 2011)
"Hypertension was prevented by olmesartan, but not by allopurinol."1.35Allopurinol attenuates L-NAME induced cardiomyopathy comparable to blockade of angiotensin receptor. ( Kasal, DA; Mandarim-de-Lacerda, CA; Neves, MF; Oigman, W, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's5 (38.46)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Shui, W1
Wang, J1
Cui, T1
Kang, C1
Zhang, Z1
Pan, JA1
Lin, H1
Wang, CQ1
Zhang, JF1
Gu, J1
Zhang, H2
Ma, Y2
Cao, R1
Wang, G1
Li, S2
Cao, Y1
Liu, M1
Liu, G1
Zhang, J2
Wang, Y1
Sung, KT1
Lo, CI1
Lai, YH1
Tsai, JP1
Yun, CH1
Hsiao, CC1
Kuo, JY1
Hou, CJ1
Hung, TC1
Su, CH1
Hung, CL1
Yeh, HI1
Song, LL1
Zhang, Y1
Zhang, XR1
Song, YN1
Dai, HZ1
Pan, KL1
Lin, JC1
Lin, CL1
Chen, MC1
Chang, PJ1
Hsiao, JF1
Chang, ST1
Chung, CM1
Radovanovic, S1
Savic-Radojevic, A1
Pekmezovic, T1
Markovic, O1
Memon, L1
Jelic, S1
Simic, D1
Radic, T1
Pljesa-Ercegovac, M1
Simic, T1
Liang, WY1
Liu, WW1
Liu, ML1
Xiang, W1
Feng, XR1
Huang, B1
Chen, XH1
Sun, YS1
Kasal, DA1
Neves, MF1
Oigman, W1
Mandarim-de-Lacerda, CA1
Chen, CC1
Hsu, YJ1
Lee, TM1
Gourine, AV1
Hu, Q1
Sander, PR1
Kuzmin, AI1
Hanafy, N1
Davydova, SA1
Zaretsky, DV1
Kurata, A1
Shigematsu, Y1
Higaki, J1
Ge, CJ1
Lu, SZ1
Chen, YD1
Wu, XF1
Hu, SJ1
Ji, Y1

Trials

1 trial available for uric acid and Cardiac Remodeling, Ventricular

ArticleYear
Synergistic effect of amlodipine and atorvastatin on blood pressure, left ventricular remodeling, and C-reactive protein in hypertensive patients with primary hypercholesterolemia.
    Heart and vessels, 2008, Volume: 23, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; C-Reactive Protein; Drug Sy

2008

Other Studies

12 other studies available for uric acid and Cardiac Remodeling, Ventricular

ArticleYear
Serum uric acid is related to left ventricular geometry and function in patients with obstructive sleep apnea.
    Sleep & breathing = Schlaf & Atmung, 2023, Volume: 27, Issue:5

    Topics: Echocardiography; Heart Ventricles; Humans; Hypertrophy, Left Ventricular; Sleep Apnea, Obstructive;

2023
Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia.
    Heart and vessels, 2020, Volume: 35, Issue:10

    Topics: Aged; Asymptomatic Diseases; Biomarkers; Blood Pressure; Databases, Factual; Diastole; Disease Progr

2020
Soluble uric acid induces myocardial damage through activating the NLRP3 inflammasome.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:15

    Topics: Animals; Apoptosis; Cell Line; Gene Knockdown Techniques; Inflammasomes; Lysosomes; Mitochondria, He

2020
Associations of serum uric acid level and gout with cardiac structure, function and sex differences from large scale asymptomatic Asians.
    PloS one, 2020, Volume: 15, Issue:7

    Topics: Adult; Asian People; Asymptomatic Diseases; Echocardiography, Doppler; Female; Gout; Heart Atria; He

2020
Theacrine attenuates myocardial fibrosis after myocardial infarction via the SIRT3/β-catenin/PPARγ pathway in estrogen-deficient mice.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:12

    Topics: Administration, Oral; Animals; Apoptosis; beta Catenin; Disease Models, Animal; Echocardiography; Es

2019
The effects of gout on left atrial volume remodelling: a prospective echocardiographic study.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:5

    Topics: Adult; Aged; Arthritis, Gouty; Atrial Remodeling; Cardiac Volume; Case-Control Studies; Cross-Sectio

2014
Uric acid and gamma-glutamyl transferase activity are associated with left ventricular remodeling indices in patients with chronic heart failure.
    Revista espanola de cardiologia (English ed.), 2014, Volume: 67, Issue:8

    Topics: Aged; Biomarkers; Disease Progression; Echocardiography; Female; gamma-Glutamyltransferase; Heart Fa

2014
Serum uric acid level and left ventricular hypertrophy in elderly male patients with nonvalvular atrial fibrillation.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2016, Volume: 26, Issue:7

    Topics: Age Factors; Aged; Aged, 80 and over; Atrial Fibrillation; Biomarkers; Chi-Square Distribution; Huma

2016
Allopurinol attenuates L-NAME induced cardiomyopathy comparable to blockade of angiotensin receptor.
    Histology and histopathology, 2008, Volume: 23, Issue:10

    Topics: Allopurinol; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomyopathies; Dis

2008
Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Allopurinol; Analysis of Variance; Animals; Antioxidants; Atrasentan; Biomarkers; Cyclic N-Oxides; D

2011
Interstitial purine metabolites in hearts with LV remodeling.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Heart Rate; He

2004
Sex-related differences in relations of uric acid to left ventricular hypertrophy and remodeling in Japanese hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:2

    Topics: Aged; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Hypertension; Hypertrophy, Left

2005