uric acid has been researched along with Carcinoma, Hepatocellular in 21 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Excerpt | Relevance | Reference |
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"To assess the degree of oxidative stress, we measured plasma ubiquinone-10 percentage (%CoQ-10) in total amounts of ubiquinone-10 in patients with chronic active hepatitis, liver cirrhosis, and hepatocellular carcinoma, and in age-matched control subjects, %CoQ-10 values were 12." | 7.70 | Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion. ( Yamamoto, Y; Yamashita, S, 1999) |
"The antioxidant defence system which plays a critical role in carcinogenesis is severely altered in aflatoxin B1 induced hepatocellular carcinoma conditions." | 7.70 | Semecarpus anacardium L. nut extract administration induces the in vivo antioxidant defence system in aflatoxin B1 mediated hepatocellular carcinoma. ( Premalatha, B; Sachdanandam, P, 1999) |
"Purine not only acts as a metabolic substrate of XOR for UA production, but it induces inflammation through IFN-γ secretion that stimulates UA production through elevation of XOR expression." | 4.12 | Purine-Induced IFN-γ Promotes Uric Acid Production by Upregulating Xanthine Oxidoreductase Expression. ( Huang, D; Li, X; Liang, B; Lin, Z; Song, X; Su, T; Wang, H; Wang, J; Xie, L, 2022) |
" The Child-Pugh score, preoperative serum uric acid and proteinuria may be used to predict the risk of post-TACE AKI in HCC patients undergo TACE." | 3.80 | Prognostic factors for acute kidney injury following transarterial chemoembolization in patients with hepatocellular carcinoma. ( Ding, Y; Du, L; Hao, L; Hou, C; Lu, D; Lv, W; Wang, R; Zhou, C, 2014) |
"To assess the degree of oxidative stress, we measured plasma ubiquinone-10 percentage (%CoQ-10) in total amounts of ubiquinone-10 in patients with chronic active hepatitis, liver cirrhosis, and hepatocellular carcinoma, and in age-matched control subjects, %CoQ-10 values were 12." | 3.70 | Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion. ( Yamamoto, Y; Yamashita, S, 1999) |
"The antioxidant defence system which plays a critical role in carcinogenesis is severely altered in aflatoxin B1 induced hepatocellular carcinoma conditions." | 3.70 | Semecarpus anacardium L. nut extract administration induces the in vivo antioxidant defence system in aflatoxin B1 mediated hepatocellular carcinoma. ( Premalatha, B; Sachdanandam, P, 1999) |
"Zajdela ascite hepatoma transplanted to the abdominal cavity of Vistar rats was used as a model of tumor growth." | 1.39 | [Effect of Zajdela ascite hepatoma growth on the extracellular antioxidant system of tumor bearer]. ( Naumov, AA; Potselueva, MM; Shatalin, IuV; Sukhomlin, TK; Zinatullina, GG, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (28.57) | 18.7374 |
1990's | 3 (14.29) | 18.2507 |
2000's | 2 (9.52) | 29.6817 |
2010's | 6 (28.57) | 24.3611 |
2020's | 4 (19.05) | 2.80 |
Authors | Studies |
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Wang, H | 3 |
Xie, L | 1 |
Song, X | 1 |
Wang, J | 5 |
Li, X | 11 |
Lin, Z | 1 |
Su, T | 1 |
Liang, B | 1 |
Huang, D | 1 |
Yu, S | 1 |
Li, Z | 3 |
Tu, L | 1 |
Pu, Y | 1 |
Yan, D | 1 |
Wang, X | 6 |
Zheng, X | 1 |
Yu, J | 1 |
Hayashi, M | 1 |
Yamada, S | 1 |
Tanabe, H | 1 |
Takami, H | 1 |
Inokawa, Y | 1 |
Sonohara, F | 1 |
Shimizu, D | 1 |
Hattori, N | 1 |
Kanda, M | 1 |
Tanaka, C | 1 |
Nakayama, G | 1 |
Koike, M | 1 |
Fujiwara, M | 1 |
Kodera, Y | 1 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 4 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Song, J | 3 |
Bascuñán, J | 2 |
Chu, Y | 1 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
Alias, A | 1 |
Zakaria, Y | 1 |
Abu-Bakar, N | 1 |
Naveed, A | 1 |
Jilani, K | 1 |
Siddique, AB | 1 |
Akbar, M | 1 |
Riaz, M | 1 |
Mushtaq, Z | 1 |
Sikandar, M | 1 |
Ilyas, S | 1 |
Bibi, I | 1 |
Asghar, A | 1 |
Rasool, G | 1 |
Irfan, M | 1 |
Li, XY | 1 |
Zhao, S | 1 |
Fan, XH | 1 |
Chen, KP | 1 |
Hua, W | 1 |
Liu, ZM | 1 |
Xue, XD | 1 |
Zhou, B | 1 |
Zhang, S | 2 |
Xing, YL | 1 |
Chen, MA | 1 |
Sun, Y | 1 |
Neradilek, MB | 1 |
Wu, XT | 1 |
Zhang, D | 2 |
Huang, W | 1 |
Cui, Y | 1 |
Yang, QQ | 1 |
Li, HW | 1 |
Zhao, XQ | 1 |
Hossein Rashidi, B | 1 |
Tarafdari, A | 1 |
Ghazimirsaeed, ST | 1 |
Shahrokh Tehraninezhad, E | 1 |
Keikha, F | 1 |
Eslami, B | 1 |
Ghazimirsaeed, SM | 1 |
Jafarabadi, M | 1 |
Silvani, Y | 1 |
Lovita, AND | 1 |
Maharani, A | 1 |
Wiyasa, IWA | 1 |
Sujuti, H | 1 |
Ratnawati, R | 1 |
Raras, TYM | 1 |
Lemin, AS | 1 |
Rahman, MM | 1 |
Pangarah, CA | 1 |
Kiyu, A | 1 |
Zeng, C | 2 |
Du, H | 1 |
Lin, D | 1 |
Jalan, D | 1 |
Rubagumya, F | 1 |
Hopman, WM | 1 |
Vanderpuye, V | 1 |
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Booth, CM | 1 |
Berry, S | 1 |
Hammad, N | 1 |
Sajo, EA | 1 |
Okunade, KS | 1 |
Olorunfemi, G | 1 |
Rabiu, KA | 1 |
Anorlu, RI | 1 |
Xu, C | 2 |
Xiang, Y | 1 |
Xu, X | 1 |
Zhou, L | 2 |
Dong, X | 1 |
Tang, S | 1 |
Gao, XC | 1 |
Wei, CH | 1 |
Zhang, RG | 1 |
Cai, Q | 1 |
He, Y | 1 |
Tong, F | 1 |
Dong, JH | 1 |
Wu, G | 1 |
Dong, XR | 1 |
Tang, X | 1 |
Tao, F | 1 |
Xiang, W | 1 |
Zhao, Y | 2 |
Jin, L | 1 |
Tao, H | 1 |
Lei, Y | 1 |
Gan, H | 1 |
Huang, Y | 1 |
Chen, Y | 3 |
Chen, L | 3 |
Shan, A | 1 |
Zhao, H | 2 |
Wu, M | 2 |
Ma, Q | 1 |
Zhang, E | 1 |
Zhang, J | 3 |
Li, Y | 5 |
Xue, F | 1 |
Deng, L | 1 |
Liu, L | 2 |
Yan, Z | 2 |
Wang, Y | 2 |
Meng, J | 1 |
Chen, G | 2 |
Anastassiadou, M | 1 |
Bernasconi, G | 1 |
Brancato, A | 1 |
Carrasco Cabrera, L | 1 |
Greco, L | 1 |
Jarrah, S | 1 |
Kazocina, A | 1 |
Leuschner, R | 1 |
Magrans, JO | 1 |
Miron, I | 1 |
Nave, S | 1 |
Pedersen, R | 1 |
Reich, H | 1 |
Rojas, A | 1 |
Sacchi, A | 1 |
Santos, M | 1 |
Theobald, A | 1 |
Vagenende, B | 1 |
Verani, A | 1 |
Du, L | 2 |
Liu, X | 1 |
Ren, Y | 1 |
Li, J | 7 |
Li, P | 1 |
Jiao, Q | 1 |
Meng, P | 1 |
Wang, F | 2 |
Wang, YS | 1 |
Wang, C | 3 |
Zhou, X | 2 |
Wang, W | 1 |
Wang, S | 2 |
Hou, J | 1 |
Zhang, A | 1 |
Lv, B | 1 |
Gao, C | 1 |
Pang, D | 1 |
Lu, K | 1 |
Ahmad, NH | 1 |
Wang, L | 1 |
Zhu, J | 2 |
Zhang, L | 2 |
Zhuang, T | 1 |
Tu, J | 1 |
Zhao, Z | 1 |
Qu, Y | 1 |
Yao, H | 1 |
Lee, DF | 1 |
Shen, J | 3 |
Wen, L | 1 |
Huang, G | 2 |
Xie, X | 1 |
Zhao, Q | 1 |
Hu, W | 1 |
Zhang, Y | 4 |
Wu, X | 1 |
Lu, J | 2 |
Li, M | 1 |
Li, W | 2 |
Wu, W | 1 |
Du, F | 1 |
Ji, H | 1 |
Yang, X | 2 |
Xu, Z | 1 |
Wan, L | 1 |
Wen, Q | 1 |
Cho, CH | 1 |
Zou, C | 1 |
Xiao, Z | 1 |
Liao, J | 1 |
Su, X | 1 |
Bi, Z | 1 |
Su, Q | 1 |
Huang, H | 1 |
Wei, Y | 2 |
Gao, Y | 2 |
Na, KJ | 1 |
Choi, H | 1 |
Oh, HR | 1 |
Kim, YH | 1 |
Lee, SB | 1 |
Jung, YJ | 1 |
Koh, J | 1 |
Park, S | 1 |
Lee, HJ | 1 |
Jeon, YK | 1 |
Chung, DH | 1 |
Paeng, JC | 1 |
Park, IK | 1 |
Kang, CH | 1 |
Cheon, GJ | 1 |
Kang, KW | 1 |
Lee, DS | 1 |
Kim, YT | 1 |
Pajuelo-Lozano, N | 1 |
Alcalá, S | 1 |
Sainz, B | 1 |
Perona, R | 1 |
Sanchez-Perez, I | 1 |
Logotheti, S | 1 |
Marquardt, S | 1 |
Gupta, SK | 1 |
Richter, C | 1 |
Edelhäuser, BAH | 1 |
Engelmann, D | 1 |
Brenmoehl, J | 1 |
Söhnchen, C | 1 |
Murr, N | 1 |
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Singh, KP | 1 |
Wolkenhauer, O | 1 |
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Spitschak, A | 1 |
Pützer, BM | 1 |
Liao, Y | 1 |
Cheng, J | 2 |
Kong, X | 1 |
Li, S | 1 |
Zhang, M | 4 |
Zhang, H | 1 |
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Dong, Y | 1 |
Xu, Y | 1 |
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Yao, Y | 1 |
Liu, Z | 2 |
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Song, Y | 1 |
Yu, K | 1 |
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Huang, Z | 1 |
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Hu, J | 2 |
Liu, Y | 4 |
Mi, Y | 1 |
Kong, H | 1 |
Xi, D | 1 |
Yan, W | 1 |
Luo, X | 1 |
Ning, Q | 1 |
Chang, X | 2 |
Zhang, T | 2 |
Wang, Q | 2 |
Rathore, MG | 1 |
Reddy, K | 1 |
Chen, H | 1 |
Shin, SH | 1 |
Ma, WY | 1 |
Bode, AM | 1 |
Dong, Z | 1 |
Mu, W | 1 |
Liu, C | 3 |
Gao, F | 1 |
Qi, Y | 1 |
Lu, H | 1 |
Zhang, X | 4 |
Cai, X | 1 |
Ji, RY | 1 |
Hou, Y | 3 |
Tian, J | 2 |
Shi, Y | 1 |
Ying, S | 1 |
Tan, M | 1 |
Feng, G | 1 |
Kuang, Y | 1 |
Chen, D | 1 |
Wu, D | 3 |
Zhu, ZQ | 1 |
Tang, HX | 1 |
Shi, ZE | 1 |
Kang, J | 1 |
Liu, Q | 1 |
Qi, J | 2 |
Mu, J | 1 |
Cong, Z | 1 |
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Celestrin, CP | 1 |
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Stein, AM | 1 |
Guadagnini, D | 1 |
Tadelle, RM | 1 |
Saad, MJA | 1 |
Oliveira, AG | 1 |
Bianconi, V | 1 |
Bronzo, P | 1 |
Banach, M | 1 |
Sahebkar, A | 1 |
Mannarino, MR | 1 |
Pirro, M | 1 |
Patsourakos, NG | 1 |
Kouvari, M | 1 |
Kotidis, A | 1 |
Kalantzi, KI | 1 |
Tsoumani, ME | 1 |
Anastasiadis, F | 1 |
Andronikos, P | 1 |
Aslanidou, T | 1 |
Efraimidis, P | 1 |
Georgiopoulos, A | 1 |
Gerakiou, K | 1 |
Grigoriadou-Skouta, E | 1 |
Grigoropoulos, P | 1 |
Hatzopoulos, D | 1 |
Kartalis, A | 1 |
Lyras, A | 1 |
Markatos, G | 1 |
Mikrogeorgiou, A | 1 |
Myroforou, I | 1 |
Orkopoulos, A | 1 |
Pavlidis, P | 1 |
Petras, C | 1 |
Riga, M | 1 |
Skouloudi, M | 1 |
Smyrnioudis, N | 1 |
Thomaidis, K | 1 |
Tsikouri, GE | 1 |
Tsikouris, EI | 1 |
Zisimos, K | 1 |
Vavoulis, P | 1 |
Vitali, MG | 1 |
Vitsas, G | 1 |
Vogiatzidis, C | 1 |
Chantanis, S | 1 |
Fousas, S | 1 |
Panagiotakos, DB | 1 |
Tselepis, AD | 1 |
Jungen, C | 1 |
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Eickholt, C | 1 |
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Dömling, A | 1 |
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Cramer, H | 1 |
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Anheyer, D | 1 |
Cantu, J | 1 |
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Gonzalez, D | 1 |
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de Oliveira, PD | 1 |
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Weinstock, RS | 1 |
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Bugielski, B | 1 |
Strayer, H | 1 |
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Singh, A | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Phase 1, Open-label, Randomized, Two-period, Two-treatment, Crossover Study to Evaluate the Effects of Food on the Pharmacokinetics of Urate After a Single Dose of Inosine in Healthy Male Subjects[NCT02614469] | Phase 1 | 18 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT02614469)
Timeframe: -12 to 0 hr pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | mg*hr/dL (Mean) |
---|---|
Inosine Fed | 2040 |
Inosine Fasted | 2031 |
(NCT02614469)
Timeframe: -12 to 0 hr pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | mg*hr/dL (Mean) |
---|---|
Inosine Fed | 267 |
Inosine Fasted | 268 |
Correction for individual endogenous urate levels was done by subtracting the individual mean endogenous baseline concentration prior to dosing from each post-dose concentration in the profile. The two samples collected at -12 h and 0 h (pre-dose) before the meal were used to measure the mean endogenous baseline concentrations in each dosing period (periods 1 and 2). (NCT02614469)
Timeframe: -12 to 0 hr pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, and 48 hrs post-dose
Intervention | mg*hr/dL (Mean) |
---|---|
Inosine Fed | 80.4 |
Inosine Fasted | 83.0 |
Correction for individual endogenous urate levels was done by subtracting the individual mean endogenous baseline concentration prior to dosing from each post-dose concentration in the profile. The two samples collected at -12 h and 0 h (pre-dose) before the meal were used to measure the mean endogenous baseline concentrations in each dosing period (periods 1 and 2). Negative concentrations were set to zero. (NCT02614469)
Timeframe: -12 to 0 hr pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | mg*hr/dL (Mean) |
---|---|
Inosine Fed | 36.1 |
Inosine Fasted | 39.3 |
Correction for individual endogenous urate levels was done by subtracting the individual mean endogenous baseline concentration prior to dosing from each post-dose concentration in the profile. The two samples collected at -12 h and 0 h (pre-dose) before the meal were used to measure the mean endogenous baseline concentrations in each dosing period (periods 1 and 2). Negative concentrations were set to zero. (NCT02614469)
Timeframe: -12 to 0 hr pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | mg/dL (Mean) |
---|---|
Inosine Fed | 1.73 |
Inosine Fasted | 1.65 |
Correction for individual endogenous urate levels was done by subtracting the individual mean endogenous baseline concentration prior to dosing from each post-dose concentration in the profile. The two samples collected at -12 h and 0 h (pre-dose) before the meal were used to measure the mean endogenous baseline concentrations in each dosing period (periods 1 and 2). (NCT02614469)
Timeframe: -12 to 0 hr pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | hr (Mean) |
---|---|
Inosine Fed | 44.3 |
Inosine Fasted | 44.7 |
Correction for individual endogenous urate levels was done by subtracting the individual mean endogenous baseline concentration prior to dosing from each post-dose concentration in the profile. The two samples collected at -12 h and 0 h (pre-dose) before the meal were used to measure the mean endogenous baseline concentrations in each dosing period (periods 1 and 2). (NCT02614469)
Timeframe: -12 to 0 h pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, and 48 hrs post-dose
Intervention | hr (Median) |
---|---|
Inosine Fed | 3.0 |
Inosine Fasted | 3.0 |
(NCT02614469)
Timeframe: -12 to 0 hrs pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36 and 48 hrs post-dose
Intervention | mg/dL (Mean) |
---|---|
Inosine Fed | 6.6 |
Inosine Fasted | 6.4 |
Number of participants with clinically significant findings in vital signs by investigator after study drug administration. (NCT02614469)
Timeframe: Up to 10 days after first study drug administration at Day 1 of Period 1
Intervention | participants (Number) |
---|---|
Inosine Fed | 0 |
Inosine Fasted | 0 |
Number of participants with adverse events after study drug administration (NCT02614469)
Timeframe: Up to 10 days after first study drug administration at Day 1 of Period 1
Intervention | participants (Number) |
---|---|
Inosine Fed | 0 |
Inosine Fasted | 0 |
(NCT02614469)
Timeframe: -12 to 0 pre-dose and 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | hr (Mean) |
---|---|
Inosine Fed | 242 |
Inosine Fasted | 241 |
(NCT02614469)
Timeframe: -12 to 0 hr pre-dose, 0.5, 1, 2, 4, 6, 8, 10, 12, 24, 36, 48 hrs post-dose
Intervention | hr (Median) |
---|---|
Inosine Fed | 3.0 |
Inosine Fasted | 3.0 |
1 review available for uric acid and Carcinoma, Hepatocellular
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
1 trial available for uric acid and Carcinoma, Hepatocellular
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
20 other studies available for uric acid and Carcinoma, Hepatocellular
Article | Year |
---|---|
Purine-Induced IFN-γ Promotes Uric Acid Production by Upregulating Xanthine Oxidoreductase Expression.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Hepatocytes; Humans; Inflammation; Interferon-gamma; Ju | 2022 |
Uricase sensitizes hepatocellular carcinoma cells to 5-fluorouracil through uricase-uric acid-UMP synthase axis.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver | 2022 |
High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences.
Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Risk Factors; | 2021 |
Overexpression of Uric Acid Transporter SLC2A9 Inhibits Proliferation of Hepatocellular Carcinoma Cells.
Topics: Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Gene Expression Regulation | 2019 |
Determination of uric acid in serum using an optical sensor based on binuclear Pd(II) 2-pyrazinecarboxamide-bipyridine doped in a sol gel matrix.
Topics: 2,2'-Dipyridyl; Carcinoma, Hepatocellular; Cardiovascular Diseases; Coordination Complexes; Gels; Hu | 2019 |
[Effect of Zajdela ascite hepatoma growth on the extracellular antioxidant system of tumor bearer].
Topics: Animals; Antioxidants; Ascites; Carcinoma, Hepatocellular; Ceruloplasmin; Disease Models, Animal; Li | 2013 |
Prognostic factors for acute kidney injury following transarterial chemoembolization in patients with hepatocellular carcinoma.
Topics: Acute Kidney Injury; Adult; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; China; | 2014 |
[Hyperleucocytosis with acute uric acid nephropathy in a patient with hepatocellular carcinoma].
Topics: Acute Kidney Injury; Aged; Carcinoma, Hepatocellular; Humans; Leukocytosis; Liver Neoplasms; Male; U | 2017 |
A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside.
Topics: Adolescent; Ammonia; Antineoplastic Agents, Alkylating; Carcinoma, Hepatocellular; Energy Metabolism | 2012 |
Catabolism of xanthine and uracil in tumor-bearing rats.
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Hydantoins; Liver Neoplasms; Neoplasms; N | 1962 |
Protective effect of Kalpaamruthaa in combating the oxidative stress posed by aflatoxin B1-induced hepatocellular carcinoma with special reference to flavonoid structure-activity relationship.
Topics: Aflatoxin B1; Analysis of Variance; Animals; Carcinoma, Hepatocellular; Catalase; Glutathione Peroxi | 2008 |
Intravenous load of fructose and fructose 1,6-diphosphate: effects on uricemia in patients with nonalcoholic liver disease.
Topics: Adult; Carcinoma, Hepatocellular; Diagnosis, Differential; Female; Fructose; Fructose-Bisphosphatase | 1996 |
Plasma ubiquinone to ubiquinol ratio in patients with hepatitis, cirrhosis, and hepatoma, and in patients treated with percutaneous transluminal coronary reperfusion.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Ascorbic Acid; beta Carotene; Biliru | 1999 |
Semecarpus anacardium L. nut extract administration induces the in vivo antioxidant defence system in aflatoxin B1 mediated hepatocellular carcinoma.
Topics: Aflatoxin B1; Animals; Antioxidants; Ascorbic Acid; Carcinogens; Carcinoma, Hepatocellular; Cytochro | 1999 |
Effect of inosine on the plasma concentration of uridine and purine bases.
Topics: Adult; Carcinoma, Hepatocellular; Creatinine; Dose-Response Relationship, Drug; Humans; Hypoxanthine | 2002 |
The role of surgery in the management of unusual complications of transcatheter arterial embolization for hepatocellular carcinoma.
Topics: Acute Disease; Adult; Aged; Carcinoma, Hepatocellular; Duodenum; Embolization, Therapeutic; Female; | 1988 |
[A case of primary hepatocellular carcinoma with hypouricemia].
Topics: Adult; Biological Transport; Carcinoma, Hepatocellular; Humans; Kidney; Liver Neoplasms; Male; Uric | 1986 |
Hypouricemia in liver cell carcinoma: an isolated renal tubular defect.
Topics: Biological Transport; Carcinoma, Hepatocellular; Humans; Kidney Tubules; Liver Neoplasms; Uric Acid | 1987 |
A study on the sensitivity test of cancer cells to anticancer drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carcinoma, He | 1966 |
Therapy for carcinoma of the liver.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Angiography; Aspartate Aminotransferases; Carcino | 1971 |