uric acid has been researched along with Brain Injuries in 15 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Secondary brain injury following hemorrhagic shock (HS) is a frequent complication in patients, even in the absence of direct brain trauma, leading to behavioral changes and more specifically anxiety and depression." | 5.62 | Targeting Uric Acid Prevents Brain Injury and Anxiety in a Rat Model of Hemorrhagic Shock. ( Bernard, F; Beyrouthy, J; Bouchard, C; Brochu, B; Charbonney, E; Gagné, MA; Gilbert, K; Khazoom, F; L'Ecuyer, S; Liu, C; Rousseau, G, 2021) |
| "Secondary brain injury following hemorrhagic shock (HS) is a frequent complication in patients, even in the absence of direct brain trauma, leading to behavioral changes and more specifically anxiety and depression." | 1.62 | Targeting Uric Acid Prevents Brain Injury and Anxiety in a Rat Model of Hemorrhagic Shock. ( Bernard, F; Beyrouthy, J; Bouchard, C; Brochu, B; Charbonney, E; Gagné, MA; Gilbert, K; Khazoom, F; L'Ecuyer, S; Liu, C; Rousseau, G, 2021) |
| "Hypertension is the most important modifiable risk factor for stroke and is associated with poorer post-stroke outcomes." | 1.56 | Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats. ( Chamorro, Á; Dantas, AP; Jiménez-Altayó, F; Jiménez-Xarrié, E; Martí-Fabregas, J; Pérez, B; Planas, AM; Puertas-Umbert, L; Vila, E, 2020) |
| "Uric acid is a major antioxidant in the blood of humans that can protect cultured neurons against oxidative and metabolic insults." | 1.34 | Soluble neuroprotective antioxidant uric acid analogs ameliorate ischemic brain injury in mice. ( Arumugam, TV; Cutler, RG; Greig, NH; Guo, Z; Haberman, F; Holloway, HW; Hyun, DH; Mattson, MP; Tang, SC; Yu, QS, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Martini, S | 1 |
| Austin, T | 1 |
| Aceti, A | 1 |
| Faldella, G | 1 |
| Corvaglia, L | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
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| Fan, XH | 1 |
| Chen, KP | 1 |
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| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
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| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
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| Lovita, AND | 1 |
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| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
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| Du, H | 1 |
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| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
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| Booth, CM | 1 |
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| Rabiu, KA | 1 |
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| Dong, X | 1 |
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| Dong, XR | 1 |
| Tang, X | 1 |
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| Zhao, Y | 2 |
| Jin, L | 1 |
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| Chen, Y | 3 |
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| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
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| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
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| Anastassiadou, M | 1 |
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| Li, P | 1 |
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| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
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| Hou, J | 1 |
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| Gao, C | 1 |
| Pang, D | 1 |
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| Ahmad, NH | 1 |
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| Zhuang, T | 1 |
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| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
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| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
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| Huang, H | 1 |
| Wei, Y | 2 |
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| Na, KJ | 1 |
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| Lee, SB | 1 |
| Jung, YJ | 1 |
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| Park, S | 1 |
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| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
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| Kang, KW | 1 |
| Lee, DS | 1 |
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| Pajuelo-Lozano, N | 1 |
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| Sainz, B | 1 |
| Perona, R | 1 |
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2 reviews available for uric acid and Brain Injuries
| Article | Year |
|---|---|
Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Asphyxia Neonatorum; Biomarkers; Brain Injuries; | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
1 trial available for uric acid and Brain Injuries
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
13 other studies available for uric acid and Brain Injuries
| Article | Year |
|---|---|
Targeting Uric Acid Prevents Brain Injury and Anxiety in a Rat Model of Hemorrhagic Shock.
Topics: Animals; Anxiety; Brain Injuries; Disease Models, Animal; Inflammation Mediators; Male; Random Alloc | 2021 |
Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats.
Topics: Animals; Antioxidants; Brain Injuries; Cerebral Revascularization; Hypertension; Infarction, Middle | 2020 |
[THE SEARCH AFTER PROGNOSTIC TESTS OF DEVELOPMENT OF UROLITHIASIS OF PATIENTS WITH VERTEBRO-CEREBROSPINAL TRAUMA].
Topics: Adult; Brain Injuries; Calcium; Case-Control Studies; Cerebrum; Creatinine; Female; Humans; Male; Mi | 2015 |
Impairment of the ability of the injured aged brain in elevating urate and ascorbate.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Axons; Brain Injuries; Corpus Callosum; Extracellular M | 2006 |
Can cerebrospinal fluid uric acid levels differentiate intraventricular hemorrhage from traumatic tap?
Topics: Brain Injuries; Cerebral Ventricles; Diagnosis, Differential; Diagnostic Techniques, Neurological; F | 2006 |
Soluble neuroprotective antioxidant uric acid analogs ameliorate ischemic brain injury in mice.
Topics: Animals; Antioxidants; Blood Flow Velocity; Brain Injuries; Brain Ischemia; Cell Culture Techniques; | 2007 |
Time course of peripheral oxidative stress as consequence of global ischaemic brain injury in rats.
Topics: Animals; Antioxidants; Brain Injuries; DNA Damage; Free Radicals; Lymphocytes; Male; Oxidative Stres | 2008 |
Neurochemical monitoring and on-line pH measurements using brain microdialysis in patients in intensive care.
Topics: Acid-Base Equilibrium; Adult; Ascorbic Acid; Blood Glucose; Blood-Brain Barrier; Brain Edema; Brain | 1994 |
Cerebral uric acid increases following experimental traumatic brain injury in rat.
Topics: Animals; Brain Injuries; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrochemistry; Fu | 1996 |
Closed head injury increases extracellular levels of antioxidants in rat hippocampus in vivo: an adaptive mechanism?
Topics: Animals; Antioxidants; Ascorbic Acid; Brain Injuries; Extracellular Space; Head Injuries, Closed; Hi | 2001 |
The prognostic value of osmolality within the first week of sustaining head injury.
Topics: Blood Glucose; Blood Proteins; Blood Urea Nitrogen; Brain Injuries; Coma; Creatinine; Humans; Osmola | 1979 |
[Metabolic studies in traumatic shock considering therapeutic measures].
Topics: Blood Cell Count; Blood Coagulation Disorders; Blood Platelets; Brain Injuries; Carbohydrate Metabol | 1979 |
Azotaemia in severe head injury--central dysregulation or renal failure?
Topics: Brain; Brain Injuries; Creatinine; Humans; Kidney; Kidney Failure, Chronic; Urea; Uremia; Uric Acid | 1978 |