uric acid has been researched along with Brain Infarction in 4 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite the promising neuroprotective effects of uric acid (UA) in acute ischemic stroke, the seemingly pleiotropic underlying mechanisms are not completely understood." | 8.02 | Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke. ( Aliena-Valero, A; Baixauli-Martín, J; Chamorro, Á; Pérez, S; Rius-Pérez, S; Salom, JB; Torregrosa, G, 2021) |
| "Uric acid (UA) has been reported to be reduced in the serum of patients with multiple sclerosis (MS) and optic neuritis (ON)." | 7.76 | Serum uric acid levels and neuromyelitis optica. ( Dai, Y; Deng, X; Hu, X; Jiang, Y; Li, Q; Long, Y; Peng, F; Qiu, W; Wu, A; Zhong, X, 2010) |
| "Uric acid has been known to exert neuroprotective effects by acting as a free radical scavenger; however, several observational studies indicated that high levels of serum uric acid increased the risk of cardiovascular events or stroke." | 5.36 | High levels of serum uric acid are associated with silent brain infarction. ( Heo, SH; Lee, SH, 2010) |
| "Despite the promising neuroprotective effects of uric acid (UA) in acute ischemic stroke, the seemingly pleiotropic underlying mechanisms are not completely understood." | 4.02 | Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke. ( Aliena-Valero, A; Baixauli-Martín, J; Chamorro, Á; Pérez, S; Rius-Pérez, S; Salom, JB; Torregrosa, G, 2021) |
| "Uric acid (UA) has been reported to be reduced in the serum of patients with multiple sclerosis (MS) and optic neuritis (ON)." | 3.76 | Serum uric acid levels and neuromyelitis optica. ( Dai, Y; Deng, X; Hu, X; Jiang, Y; Li, Q; Long, Y; Peng, F; Qiu, W; Wu, A; Zhong, X, 2010) |
| "Uric acid has been known to exert neuroprotective effects by acting as a free radical scavenger; however, several observational studies indicated that high levels of serum uric acid increased the risk of cardiovascular events or stroke." | 1.36 | High levels of serum uric acid are associated with silent brain infarction. ( Heo, SH; Lee, SH, 2010) |
| "Fourteen patients developed symptomatic brain infarction (BI) during follow-up." | 1.35 | Association between future events of brain infarction and soluble levels of intercellular adhesion molecule-1 and C-reactive protein in patients with type 2 diabetes mellitus. ( Hamada, Y; Hotta, N; Kanai, A; Kawamura, T; Nagashima, M; Nakamura, J; Nakamura, N; Nakashima, E; Nakayama, M; Sano, T; Umemura, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aliena-Valero, A | 1 |
| Rius-Pérez, S | 1 |
| Baixauli-Martín, J | 1 |
| Torregrosa, G | 1 |
| Chamorro, Á | 1 |
| Pérez, S | 1 |
| Salom, JB | 1 |
| Kanai, A | 1 |
| Kawamura, T | 1 |
| Umemura, T | 1 |
| Nagashima, M | 1 |
| Nakamura, N | 1 |
| Nakayama, M | 1 |
| Sano, T | 1 |
| Nakashima, E | 1 |
| Hamada, Y | 1 |
| Nakamura, J | 1 |
| Hotta, N | 1 |
| Peng, F | 1 |
| Zhong, X | 1 |
| Deng, X | 1 |
| Qiu, W | 1 |
| Wu, A | 1 |
| Long, Y | 1 |
| Hu, X | 1 |
| Li, Q | 1 |
| Jiang, Y | 1 |
| Dai, Y | 1 |
| Heo, SH | 1 |
| Lee, SH | 1 |
4 other studies available for uric acid and Brain Infarction
| Article | Year |
|---|---|
Uric Acid Neuroprotection Associated to IL-6/STAT3 Signaling Pathway Activation in Rat Ischemic Stroke.
Topics: Animals; Antioxidants; Apoptosis; Body Weight; Brain Edema; Brain Infarction; Cytokines; Gene Expres | 2021 |
Association between future events of brain infarction and soluble levels of intercellular adhesion molecule-1 and C-reactive protein in patients with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Brain Infarction; C-Reactive Protein; Diabet | 2008 |
Serum uric acid levels and neuromyelitis optica.
Topics: Adolescent; Adult; Aged; Brain Infarction; Case-Control Studies; Child; Child, Preschool; China; Coh | 2010 |
High levels of serum uric acid are associated with silent brain infarction.
Topics: Adult; Aged; Analysis of Variance; Brain; Brain Infarction; C-Reactive Protein; Cardiovascular Disea | 2010 |