uric acid has been researched along with Brain Disorders in 28 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since uric acid is associated with cardiovascular and renal disease, a treatment to maintain blood uric acid level may be required in patients with hyperuricemia." | 9.24 | Rationale, design, and baseline characteristics of a study to evaluate the effect of febuxostat in preventing cerebral, cardiovascular, and renal events in patients with hyperuricemia. ( Hayashi, T; Hiramitsu, S; Hisatome, I; Jinnouchi, H; Kakuda, H; Kawai, N; Kimura, K; Kojima, S; Matsui, K; Mori, H; Ogawa, H; Ohya, Y; Saito, Y; Sugawara, M; Tokutake, E; Uchiyama, K; Wakasa, Y; Waki, M; Yokota, N, 2017) |
| "The serum uric acid (UA) levels were measured in 112 patients with multiple sclerosis (MS) and 794 patients with different types of other neurological diseases (OND) or healthy control group." | 7.74 | Serum uric acid levels of patients with multiple sclerosis and other neurological diseases. ( Hu, X; Li, J; Pei, Z; Peng, F; Qiu, W; Xu, G; Zhang, B; Zhong, X, 2008) |
| "Since uric acid is associated with cardiovascular and renal disease, a treatment to maintain blood uric acid level may be required in patients with hyperuricemia." | 5.24 | Rationale, design, and baseline characteristics of a study to evaluate the effect of febuxostat in preventing cerebral, cardiovascular, and renal events in patients with hyperuricemia. ( Hayashi, T; Hiramitsu, S; Hisatome, I; Jinnouchi, H; Kakuda, H; Kawai, N; Kimura, K; Kojima, S; Matsui, K; Mori, H; Ogawa, H; Ohya, Y; Saito, Y; Sugawara, M; Tokutake, E; Uchiyama, K; Wakasa, Y; Waki, M; Yokota, N, 2017) |
| "High uric acid (UA) levels can cause gout, urolithiasis and acute and chronic nephropathy, all of which are due to the deposit of urate crystals." | 4.87 | Is there anything good in uric acid? ( Alvarez-Lario, B; Macarrón-Vicente, J, 2011) |
| "The serum uric acid (UA) levels were measured in 112 patients with multiple sclerosis (MS) and 794 patients with different types of other neurological diseases (OND) or healthy control group." | 3.74 | Serum uric acid levels of patients with multiple sclerosis and other neurological diseases. ( Hu, X; Li, J; Pei, Z; Peng, F; Qiu, W; Xu, G; Zhang, B; Zhong, X, 2008) |
| "Uric acid levels were related to serum creatinine (p < 0." | 1.32 | Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants. ( Rozycki, HJ; Sysyn, GD, 2003) |
| "An occasional child will have marked leukocytosis and disturbance of organ function due to massive leukemic infiltrates." | 1.25 | Complications and total care of a child with acute leukemia. ( Ragab, AH; Vietti, TJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (64.29) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 2 |
| Liu, D | 2 |
| Yin, Z | 1 |
| Fang, Z | 1 |
| Yang, M | 1 |
| Du, X | 1 |
| Nie, B | 1 |
| Gao, K | 1 |
| Kojima, S | 1 |
| Matsui, K | 1 |
| Ogawa, H | 1 |
| Jinnouchi, H | 1 |
| Hiramitsu, S | 1 |
| Hayashi, T | 1 |
| Yokota, N | 1 |
| Kawai, N | 1 |
| Tokutake, E | 1 |
| Uchiyama, K | 1 |
| Sugawara, M | 1 |
| Kakuda, H | 1 |
| Wakasa, Y | 1 |
| Mori, H | 1 |
| Hisatome, I | 1 |
| Waki, M | 1 |
| Ohya, Y | 1 |
| Kimura, K | 1 |
| Saito, Y | 1 |
| Ngu, LH | 1 |
| Afroze, B | 1 |
| Chen, BC | 1 |
| Affandi, O | 1 |
| Zabedah, MY | 1 |
| Alvarez-Lario, B | 1 |
| Macarrón-Vicente, J | 1 |
| Sysyn, GD | 1 |
| Rozycki, HJ | 1 |
| Farstad, M | 1 |
| Haug, JO | 1 |
| Lindbak, H | 1 |
| Skaug, OE | 1 |
| Peng, F | 1 |
| Zhang, B | 1 |
| Zhong, X | 1 |
| Li, J | 1 |
| Xu, G | 1 |
| Hu, X | 1 |
| Qiu, W | 1 |
| Pei, Z | 1 |
| Soni, SS | 1 |
| Adikey, GK | 1 |
| Raman, AS | 1 |
| Manzke, H | 1 |
| Staemmler, W | 1 |
| Maesaka, JK | 2 |
| Venkatesan, J | 2 |
| Piccione, JM | 2 |
| Decker, R | 2 |
| Dreisbach, AW | 2 |
| Wetherington, J | 1 |
| Reynolds, TB | 1 |
| Lieberman, FL | 1 |
| Goodman, AR | 1 |
| Mellor, D | 1 |
| Vietti, TJ | 1 |
| Ragab, AH | 1 |
| Wetherington, JD | 1 |
| Ruth, VJ | 1 |
| Raivio, KO | 1 |
| Astakhova, LN | 1 |
| Asanova, NK | 1 |
| Dormoy, O | 1 |
| Ajzenberg, D | 1 |
| Champanier, JP | 1 |
| Etienne, JC | 1 |
| Gougeon, J | 1 |
| Pascalis, G | 1 |
| Young, IJ | 2 |
| Crampton, AR | 1 |
| Labrune, B | 2 |
| Cartier, P | 2 |
| Bonnenfant, F | 2 |
| Ribierre, M | 2 |
| Mallet, R | 2 |
| Rowley, WF | 1 |
| Becker, B | 1 |
| Gaballah, S | 1 |
| Singh, SD | 1 |
| Sepaha, HC | 1 |
| Vijayvargiyd, R | 1 |
| Chhaparwal, BC | 1 |
| Pohowalla, JN | 1 |
| Nyhan, WL | 1 |
| Sweetman, L | 1 |
| Carpenter, DG | 1 |
| Carter, CH | 1 |
| Hoefnagel, D | 1 |
| Hooft, C | 1 |
| Van Nevel, C | 1 |
| De Schaepdryver, AF | 1 |
| Rosenberg, D | 1 |
| Monnet, P | 1 |
| Mamelle, JC | 1 |
| Colombel, M | 1 |
| Salle, B | 1 |
| Bovier-Lapierre, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Comparative Trial on the Effect of Febuxostat in Preventing Cerebral and Cardiorenovascular Events in Patients With Hyperuricemia[NCT01984749] | 1,000 participants (Anticipated) | Interventional | 2013-11-30 | Active, not recruiting | |||
| Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987] | 122 participants (Actual) | Observational | 2019-07-30 | Completed | |||
| Effects of Adding Hypertonic Saline Solutions and/or Etilefrine to Standard Diuretics Therapy in Egyptian Cirrhotic Patients With Ascites[NCT04785755] | Phase 2 | 90 participants (Actual) | Interventional | 2017-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for uric acid and Brain Disorders
| Article | Year |
|---|---|
Is there anything good in uric acid?
Topics: Age Factors; Brain Diseases; Cardiovascular Diseases; Female; Gout; Humans; Hypertension; Hyperurice | 2011 |
Encephalitis and encephalopathy in childhood leukaemia.
Topics: Antineoplastic Agents; Asparaginase; Brain Diseases; Brain Neoplasms; Child; Encephalitis; Humans; L | 1976 |
2 trials available for uric acid and Brain Disorders
| Article | Year |
|---|---|
Rationale, design, and baseline characteristics of a study to evaluate the effect of febuxostat in preventing cerebral, cardiovascular, and renal events in patients with hyperuricemia.
Topics: Aged; Aged, 80 and over; Brain Diseases; Cardiovascular Diseases; Cause of Death; Febuxostat; Female | 2017 |
Advantages of treatment of ascites without sodium restriction and without complete removal of excess fluid.
Topics: Blood Urea Nitrogen; Brain Diseases; Creatinine; Diuresis; Humans; Liver Cirrhosis; Random Allocatio | 1978 |
24 other studies available for uric acid and Brain Disorders
| Article | Year |
|---|---|
Retrospective case-control study on screening risk factors of antibiotic-associated encephalopathy in patients with chronic kidney disease.
Topics: Albumins; Anti-Bacterial Agents; Brain Diseases; Case-Control Studies; Humans; Phosphorus; Renal Ins | 2022 |
Retrospective case-control study on screening risk factors of antibiotic-associated encephalopathy in patients with chronic kidney disease.
Topics: Albumins; Anti-Bacterial Agents; Brain Diseases; Case-Control Studies; Humans; Phosphorus; Renal Ins | 2022 |
Retrospective case-control study on screening risk factors of antibiotic-associated encephalopathy in patients with chronic kidney disease.
Topics: Albumins; Anti-Bacterial Agents; Brain Diseases; Case-Control Studies; Humans; Phosphorus; Renal Ins | 2022 |
Retrospective case-control study on screening risk factors of antibiotic-associated encephalopathy in patients with chronic kidney disease.
Topics: Albumins; Anti-Bacterial Agents; Brain Diseases; Case-Control Studies; Humans; Phosphorus; Renal Ins | 2022 |
Predictive value of serum uric acid levels on mortality in acute coronary syndrome patients with chronic kidney disease after drug-eluting stent implantation.
Topics: Aged; Angina, Unstable; Brain Diseases; China; Drug-Eluting Stents; Female; Glomerular Filtration Ra | 2013 |
Molybdenum cofactor deficiency in a Malaysian child.
Topics: Brain Diseases; Child; Coenzymes; Cysteine; Diagnosis, Differential; Humans; Hypoxanthine; Hypoxia; | 2009 |
Lack of prognostic significance of early elevated serum uric acid levels in low birthweight infants.
Topics: Apgar Score; Brain Diseases; Cerebral Hemorrhage; Creatinine; Gestational Age; Humans; Infant, Low B | 2003 |
URIC ACID IN THE CEREBROSPINAL FLUID IN CEREBRAL ATROPHY.
Topics: Atrophy; Blood Chemical Analysis; Brain Diseases; Cerebrospinal Fluid; Humans; Nervous System Diseas | 1965 |
Serum uric acid levels of patients with multiple sclerosis and other neurological diseases.
Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Child, Preschool; Encephalitis; Female; Humans; Male | 2008 |
Fractional excretion of uric acid as a therapeutic monitor in cerebral salt wasting syndrome.
Topics: Aged; Biomarkers; Brain Diseases; Humans; Hyponatremia; Male; Stroke; Uric Acid; Wasting Syndrome | 2008 |
Oxypurine concentration in the CSF in children with different diseases of the nervous system.
Topics: Brain Diseases; Humans; Hydrocephalus; Hypoxanthines; Infant; Infant, Newborn; Leukemia, Lymphoid; M | 1981 |
Plasma natriuretic factor(s) in patients with intracranial disease, renal salt wasting and hyperuricosuria.
Topics: Adult; Animals; Biological Transport; Brain Diseases; Dose-Response Relationship, Drug; Female; Huma | 1993 |
Complications and total care of a child with acute leukemia.
Topics: Acute Disease; Adolescent; Agranulocytosis; Anemia; Antineoplastic Agents; Bacterial Infections; Bon | 1975 |
Abnormal urate transport in patients with intracranial disease.
Topics: Biological Transport; Brain Diseases; Female; Humans; Kidney Tubules; Male; Middle Aged; Prospective | 1992 |
Purine metabolites as measures of birth asphyxia and predictors of brain damage.
Topics: Adult; Asphyxia Neonatorum; Brain Diseases; Female; Humans; Hypoxanthines; Infant, Newborn; Male; Pr | 1989 |
[Borderline neuropsychiatric disorders in purine metabolism disorders in children].
Topics: Adolescent; Arthritis; Brain Diseases; Child; Child, Preschool; Disease Susceptibility; Female; Huma | 1985 |
[Familial encephalopathy with oligophrenia and congenital indifference to pain and Laurence-Moon-Bardet-Biedl syndrome].
Topics: Alkaline Phosphatase; Brain Diseases; Child; Esterases; Female; Glucosephosphate Dehydrogenase; Huma | 1970 |
Medical Grand Rounds from the University of Alabama Medical Center. Lead poisoning.
Topics: Adult; Aged; Alcoholism; Amyotrophic Lateral Sclerosis; Anemia, Macrocytic; Brain Diseases; Diagnosi | 1972 |
[Encephalopathy with self mutilations in a twin. Normal HGPRT activity. Hyperuricosuria without major hyperuricemia. Apropos of the limits of the Lesch-Nyham syndrome].
Topics: Adolescent; Brain Diseases; Diagnosis, Differential; Diseases in Twins; Humans; Lesch-Nyhan Syndrome | 1972 |
Cerebrospinal fluid uric acid levels in cerebral atrophy occurring in psychiatric and neurologic patients.
Topics: Adult; Age Factors; Aged; Alcoholism; Atrophy; Brain Diseases; Female; Hospitalization; Humans; Male | 1974 |
[Familial encephalopathy with hyperuricemia. A study of purine metabolism and therapeutic attempts].
Topics: Brain Diseases; Child, Preschool; Electroencephalography; Follow-Up Studies; Gout; Humans; Infant; K | 1969 |
Cerebrospinal fluid levels of uric acid in cortical atrophy.
Topics: Adult; Aged; Analysis of Variance; Brain Diseases; Cerebral Cortex; Hospitalization; Hospitals, Psyc | 1969 |
Uric acid levels in serum and C.S.F. in neurological disorders.
Topics: Blood-Brain Barrier; Brain Diseases; Cerebral Cortex; Child; Humans; Uric Acid | 1970 |
Effects of azathiprine in a disorder of uric acid metabolism and cerebral function.
Topics: Adult; Azathioprine; Blood Platelets; Brain Diseases; Child; Gout; Hematocrit; Hemoglobinometry; Hum | 1968 |
[Familial encephalopathy with hyperuricemia. Study of purine metabolism. Therapeutic endeavors].
Topics: Adult; Brain Diseases; Child, Preschool; Humans; Infant; Intellectual Disability; Male; Purine-Pyrim | 1968 |
Hyperuricosuric encephalopathy without hyperuricaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Body Weight; Brain Diseases; Carbon Isotopes; Child, Preschool | 1968 |
[Encephalopathy with disorders of purine metabolism. Familial case].
Topics: Adenosine Triphosphate; Allopurinol; Anemia; Brain Diseases; Carbon Isotopes; Child, Preschool; Eryt | 1968 |