Page last updated: 2024-10-20

uric acid and Bone Fractures

uric acid has been researched along with Bone Fractures in 15 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Crystal arthritis is the most common type of inflammatory arthritis, and fractures contribute to significant morbidity and mortality, therefore, the relationship between the two is of clinical importance."2.58Crystalline arthropathy and bone health. ( Chang, I; Gazeley, D, 2018)
"Gout was not associated with a risk of non-vertebral fracture."1.46Gout and the Risk of Non-vertebral Fracture. ( Curhan, GC; Kim, SC; Liu, J; Paik, JM; Solomon, DH, 2017)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's4 (26.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Xu, N1
Wang, Y1
Chen, Y1
Guo, YN1
Li, RX1
Zhou, YM1
Xu, J1
Wang, G1
Zhuo, N1
Yan, D1
Liu, Z1
Lai, SW1
Kuo, YH1
Liao, KF1
Chang, I1
Gazeley, D1
Yan, P1
Zhang, Z1
Wan, Q1
Zhu, J1
Li, H1
Gao, C1
Ma, H1
Xu, Y1
Kim, SC1
Paik, JM1
Liu, J1
Curhan, GC1
Solomon, DH1
Kortan, N1
Roberts, J1
Roebuck, J1
Maggio, D1
Barabani, M1
Pierandrei, M1
Polidori, MC1
Catani, M1
Mecocci, P1
Senin, U1
Pacifici, R1
Cherubini, A1
Black, DM1
Greenspan, SL1
Ensrud, KE1
Palermo, L1
McGowan, JA1
Lang, TF1
Garnero, P1
Bouxsein, ML1
Bilezikian, JP1
Rosen, CJ1
Newman, JH1
Schweda, E1
Podlesch, I1
Heller, W1
Domres, B1
Hausdörfer, J1
Veihelmann, D1
Bennett, AH1
Colodny, AH1
Flückiger, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Trial of Parathyroid Hormone (PTH) and Alendronate in Combination in the Treatment of Osteoporosis[NCT00005005]Phase 2238 participants (Actual)Interventional1999-10-31Completed
The Denosumab And Teriparatide Administration Study (DATA)[NCT00926380]Phase 294 participants (Actual)Interventional2009-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Spine Bone Density From Baseline to 2 Years

(NCT00926380)
Timeframe: Baseline and 2 years

Interventionpercent change (Mean)
Denosumab ONLY8.3
Teriparatide (Forteo®) ONLY9.5
Denosumab and Teriparatide (Forteo®)12.9

Reviews

1 review available for uric acid and Bone Fractures

ArticleYear
Crystalline arthropathy and bone health.
    Current opinion in rheumatology, 2018, Volume: 30, Issue:2

    Topics: Bone and Bones; Bone Density; Chondrocalcinosis; Crystal Arthropathies; Fractures, Bone; Gout; Human

2018

Trials

1 trial available for uric acid and Bone Fractures

ArticleYear
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density; Bone Remodel

2003
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density; Bone Remodel

2003
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density; Bone Remodel

2003
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Alendronate; Biomarkers; Bone Density; Bone Remodel

2003

Other Studies

13 other studies available for uric acid and Bone Fractures

ArticleYear
The associations between uric acid with BMDs and risk of the 10-year probability of fractures in Chinese patients with T2DM stratified by age and gender.
    Endocrine, 2023, Volume: 80, Issue:3

    Topics: Absorptiometry, Photon; Aged; Bone Density; Cross-Sectional Studies; Diabetes Mellitus, Type 2; East

2023
Lowering serum urate level to a guideline-based target is associated with a lower risk of incident fracture in people with gout: comment on the article by Wei et al.
    Arthritis & rheumatology (Hoboken, N.J.), 2023, Volume: 75, Issue:10

    Topics: Fractures, Bone; Gout; Gout Suppressants; Humans; Risk; Treatment Outcome; Uric Acid

2023
Serum uric acid and the risk of incident hip fractures in women and men.
    Maturitas, 2021, Volume: 154

    Topics: Accidental Falls; Bone Density; Female; Fractures, Bone; Hip Fractures; Humans; Incidence; Male; Ost

2021
Association of serum uric acid with bone mineral density and clinical fractures in Chinese type 2 diabetes mellitus patients: A cross-sectional study.
    Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 486

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bone Density; China; Cross-Sectional Studies;

2018
Gout and the Risk of Non-vertebral Fracture.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2017, Volume: 32, Issue:2

    Topics: Cohort Studies; Female; Fractures, Bone; Gout; Humans; Male; Middle Aged; Risk Factors; Uric Acid

2017
Gout masquerading as a triquetral fracture.
    The Journal of rheumatology, 2010, Volume: 37, Issue:3

    Topics: Adrenal Cortex Hormones; Diagnosis, Differential; Fractures, Bone; Gout; Humans; Male; Middle Aged;

2010
Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:4

    Topics: Activities of Daily Living; Aged; Aging; Antioxidants; Ascorbic Acid; Body Mass Index; Bone and Bone

2003
POLYCYTHEMIA vera, compression fractures and hyperuricemia.
    The American journal of medicine, 1958, Volume: 25, Issue:1

    Topics: Fractures, Bone; Fractures, Compression; Humans; Hyperuricemia; Medical Records; Polycythemia Vera;

1958
The differential diagnosis of septic arthritis in the elderly.
    Comprehensive therapy, 1984, Volume: 10, Issue:8

    Topics: Aged; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Cellulitis; Diabetic Neuropathies; Di

1984
[Postoperative nutrition of maxillary surgery patients with the instant formula diet].
    Infusionstherapie und klinische Ernahrung, 1982, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Glucose; Creatinine; Electrolytes; Enteral Nutrition; Facial Neoplasm

1982
[Metabolic studies in traumatic shock considering therapeutic measures].
    Die Medizinische Welt, 1979, Jun-22, Volume: 30, Issue:25

    Topics: Blood Cell Count; Blood Coagulation Disorders; Blood Platelets; Brain Injuries; Carbohydrate Metabol

1979
Urinary tract calculi in children.
    The Journal of urology, 1973, Volume: 109, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Colon, Sigmoid; Crohn Disease; Cystinuria; Female; Fract

1973
[Fracture healing in hyperuricemia].
    Praxis, 1969, Jun-24, Volume: 58, Issue:25

    Topics: Adolescent; Adult; Aged; Female; Fractures, Bone; Gout; Humans; Male; Middle Aged; Uric Acid; Wound

1969