Page last updated: 2024-10-20

uric acid and Behavior Disorders

uric acid has been researched along with Behavior Disorders in 24 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to investigate the correlation between serum uric acid (UA) levels and the clinical characteristics of depression."7.78Serum uric acid levels and the clinical characteristics of depression. ( Cheng, M; Li, G; Peng, F; Wang, H; Wen, S; Yue, J; Zheng, L; Zhong, Z, 2012)
"5% potassium oxonate (an uricase inhibitor) to induce hyperuricemia."3.91Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson's disease. ( Dohgu, S; Fukae, J; Kataoka, Y; Koga, M; Matsumoto, J; Nakashima, A; Takata, F; Tsuboi, Y; Yamauchi, A, 2019)
"This study was designed to investigate the correlation between serum uric acid (UA) levels and the clinical characteristics of depression."3.78Serum uric acid levels and the clinical characteristics of depression. ( Cheng, M; Li, G; Peng, F; Wang, H; Wen, S; Yue, J; Zheng, L; Zhong, Z, 2012)
"In contrast, at complete HPRT deficiency, besides overproduction of uric acid neurological problems appear including spasticity, choreoathetosis, mental retardation, and compulsive self-mutilation."1.32The biochemical basis of the neurobehavioral abnormalities in the Lesch-Nyhan syndrome: a hypothesis. ( Mitev, VI; Neychev, VK, 2004)
" (3) Zotepine decreased serum uric acid level parallel with its dosage (r=0."1.26[Effects of zotepine, a psychotropic agent, on the serum uric acid level of inpatients at a psychiatric hospital]. ( Kaiya, H; Kondo, T; Sanpei, F; Takeda, N; Takeuchi, K; Yoshida, H, 1982)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199014 (58.33)18.7374
1990's1 (4.17)18.2507
2000's1 (4.17)29.6817
2010's5 (20.83)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Constantin, IM1
Voruz, P1
Péron, JA1
Martorell, M1
Lucas, X1
Alarcón-Zapata, P1
Capó, X1
Quetglas-Llabrés, MM1
Tejada, S1
Sureda, A1
Zhao, SS1
Qian, Y1
Mackie, SL1
Wen, C1
Mao, Y1
Nakashima, A1
Yamauchi, A1
Matsumoto, J1
Dohgu, S1
Takata, F1
Koga, M1
Fukae, J1
Tsuboi, Y1
Kataoka, Y1
Sutin, AR1
Cutler, RG1
Camandola, S1
Uda, M1
Feldman, NH1
Cucca, F1
Zonderman, AB1
Mattson, MP1
Ferrucci, L1
Schlessinger, D1
Terracciano, A1
Moccia, M1
Picillo, M1
Erro, R1
Vitale, C1
Longo, K1
Amboni, M1
Santangelo, G1
Spina, E1
De Rosa, A1
De Michele, G1
Santoro, L1
Barone, P1
Pellecchia, MT1
Jinnah, HA1
Ceballos-Picot, I1
Torres, RJ1
Visser, JE1
Schretlen, DJ1
Verdu, A1
Laróvere, LE1
Chen, CJ1
Cossu, A1
Wu, CH1
Sampat, R1
Chang, SJ1
de Kremer, RD1
Nyhan, W1
Harris, JC1
Reich, SG1
Puig, JG1
Wen, S1
Cheng, M1
Wang, H2
Yue, J1
Li, G1
Zheng, L1
Zhong, Z1
Peng, F1
DREYFUSS, F1
CZACZKES, JW1
CALVY, GL1
HEALEY, LA1
HARRISON, M1
DECKER, JL1
Farstad, M1
Skaug, OE1
Solheim, DM1
Neychev, VK1
Mitev, VI1
Yoshida, H1
Kaiya, H1
Kondo, T1
Sanpei, F1
Takeda, N1
Takeuchi, K1
Mauch, E1
Mayer, G1
Kornhuber, A1
Krapf, H1
Jürgens, R1
Hufnagl, JM1
Kornhuber, HH1
Flemenbaum, A1
Anderson, RP1
Brooks, SC1
Linn, JJ1
Disney, N1
Astakhova, LN1
Asanova, NK1
Goldstein, JL1
Fialkow, PJ1
Labrune, B1
Cartier, P1
Bonnenfant, F1
Ribierre, M1
Mallet, R1
Moure, JM1
Whitecar, JP1
Bodey, GP1
Eastwood, MR1
Trevelyan, H1
Emmerson, BT1
Bluestone, R1

Reviews

2 reviews available for uric acid and Behavior Disorders

ArticleYear
Targeting Xanthine Oxidase by Natural Products as a Therapeutic Approach for Mental Disorders.
    Current pharmaceutical design, 2021, Volume: 27, Issue:3

    Topics: Allopurinol; Biological Products; Humans; Mental Disorders; Uric Acid; Xanthine Oxidase

2021
Attenuated variants of Lesch-Nyhan disease.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 3

    Topics: Adolescent; Adult; Age of Onset; Aged; Child; Child, Preschool; Cognition Disorders; Cohort Studies;

2010

Other Studies

22 other studies available for uric acid and Behavior Disorders

ArticleYear
Moderating effects of uric acid and sex on cognition and psychiatric symptoms in asymmetric Parkinson's disease.
    Biology of sex differences, 2023, 05-04, Volume: 14, Issue:1

    Topics: Cognition; Female; Functional Laterality; Humans; Male; Mental Disorders; Parkinson Disease; Uric Ac

2023
Genetically predicted serum urate levels have no causal role on depression or other psychiatric disorders.
    Clinical rheumatology, 2021, Volume: 40, Issue:9

    Topics: Anxiety; Causality; Depression; Depressive Disorder, Major; Genome-Wide Association Study; Gout; Hum

2021
Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson's disease.
    Behavioural pharmacology, 2019, Volume: 30, Issue:1

    Topics: Adrenergic Agents; Animals; Apomorphine; Disease Models, Animal; Hyperuricemia; Male; Mental Disorde

2019
Impulsivity is associated with uric acid: evidence from humans and mice.
    Biological psychiatry, 2014, Jan-01, Volume: 75, Issue:1

    Topics: Adult; Aged; Animals; Cohort Studies; Disease Models, Animal; Exploratory Behavior; Female; Humans;

2014
Is serum uric acid related to non-motor symptoms in de-novo Parkinson's disease patients?
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:7

    Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Female; Humans; Male; Men

2014
Serum uric acid levels and the clinical characteristics of depression.
    Clinical biochemistry, 2012, Volume: 45, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Depression; Female; Humans; Male;

2012
Blood cholesterol and uric acid of healthy medical students under the stress of an examination.
    A.M.A. archives of internal medicine, 1959, Volume: 103, Issue:5

    Topics: Cholesterol; Humans; Mental Disorders; Stress, Physiological; Students, Medical; Uric Acid

1959
THE PREDICTION OF DISEASE.
    Military medicine, 1964, Volume: 129

    Topics: Allergy and Immunology; Blood Pressure; Cholesterol; Coronary Disease; Diabetes Mellitus; Electronic

1964
URICOSURIC EFFECT OF CHLORPROTHIXENE.
    The New England journal of medicine, 1965, Mar-11, Volume: 272

    Topics: Biomedical Research; Blood; Chlorprothixene; Drug Therapy; Humans; Intellectual Disability; Mental D

1965
URIC ACID IN THE CEREBROSPINAL FLUID IN PSYCHIATRIC DISORDERS.
    Acta neurologica Scandinavica, 1965, Volume: 41, Issue:1

    Topics: Blood Chemical Analysis; Cerebrospinal Fluid; Humans; Mental Disorders; Psychotic Disorders; Uric Ac

1965
The biochemical basis of the neurobehavioral abnormalities in the Lesch-Nyhan syndrome: a hypothesis.
    Medical hypotheses, 2004, Volume: 63, Issue:1

    Topics: Animals; Biochemistry; Brain; Humans; Hypoxanthine Phosphoribosyltransferase; Intellectual Disabilit

2004
[Effects of zotepine, a psychotropic agent, on the serum uric acid level of inpatients at a psychiatric hospital].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1982, Volume: 2, Issue:2

    Topics: Adult; Antipsychotic Agents; Creatinine; Dibenzothiepins; Female; Humans; Male; Mental Disorders; Mi

1982
[The significance of quantitative computerized tomography in the long-term prognosis of ischemic stroke].
    Die Rehabilitation, 1994, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Brain; Cerebral Infarction; Child; Com

1994
Field dependence and blood cholesterol: an expansion.
    Perceptual and motor skills, 1978, Volume: 46, Issue:3 Pt 1

    Topics: Adolescent; Adult; Affective Symptoms; Age Factors; Aged; Body Height; Body Weight; Cholesterol; Fem

1978
Serotonin, folic acid, and uric acid metabolism in the diagnosis of neuropsychiatric disorders.
    Biological psychiatry, 1978, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Bipolar Disorder; Brain; Carbolines; Female; Folic Acid; Hallucinations; Humans;

1978
[Borderline neuropsychiatric disorders in purine metabolism disorders in children].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:3

    Topics: Adolescent; Arthritis; Brain Diseases; Child; Child, Preschool; Disease Susceptibility; Female; Huma

1985
The Alström syndrome. Report of three cases with further delineation of the clinical, pathophysiological, and genetic aspects of the disorder.
    Medicine, 1973, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Albuminuria; Blood Cell Count; Blood Urea Nitrogen; Child; Complement System Prot

1973
[Familial encephalopathy with hyperuricemia. A study of purine metabolism and therapeutic attempts].
    Archives francaises de pediatrie, 1969, Volume: 26, Issue:2

    Topics: Brain Diseases; Child, Preschool; Electroencephalography; Follow-Up Studies; Gout; Humans; Infant; K

1969
Electroencephalogram changes secondary to asparaginase.
    Archives of neurology, 1970, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Ammonia; Asparaginase; Child; Child, Preschool; Electroencephalography; Hum

1970
Stress and coronary heart disease.
    Journal of psychosomatic research, 1971, Volume: 15, Issue:3

    Topics: Adult; Blood Pressure; Cholesterol; Coronary Disease; Employment; Female; Humans; Male; Mass Screeni

1971
The clinical differentiation of lead gout from primary gout.
    Arthritis and rheumatism, 1968, Volume: 11, Issue:5

    Topics: Alcohol Drinking; Body Height; Body Weight; Child Behavior Disorders; Diagnosis, Differential; Envir

1968
Nyhan-Lesch syndrome and juvenile gout (2 cases).
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:11 Part 1

    Topics: Adult; Child, Preschool; Deficiency Diseases; Gout; Guanine; Humans; Hypoxanthines; Kidney Failure,

1968