Page last updated: 2024-10-20

uric acid and Atrophy

uric acid has been researched along with Atrophy in 12 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the association between baseline uric acid and the primary composite outcome of doubling of interstitium or ESRD from interstitial fibrosis and tubular atrophy (IF/TA) in the Angiotensin II Blockade for Chronic Allograft Nephropathy (ABCAN) Trial participants."9.19Uric acid and allograft loss from interstitial fibrosis/tubular atrophy: post hoc analysis from the angiotensin II blockade in chronic allograft nephropathy trial. ( Hart, A; Ibrahim, HN; Jackson, S; Kasiske, BL; Matas, AJ; Mauer, MS; Najafian, B; Spong, R, 2014)
"Among patients with immunoglobulin A nephropathy, the higher levels of fibrinogen and uric acid may mean a higher score of tubular atrophy/interstitial fibrosis, which suggests the renal biopsy should be performed for these patients as early as possible to defined pathological classification, even though there is no obvious abnormal change in the test of renal function."8.12A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score. ( Hu, S; Lou, Z; Tu, M, 2022)
"Renal handling of uric acid and clinical prognosis following episodes of macroscopic hematuria (EMH) were examined in 113 patients with IgA nephropathy (IgAN)."7.68Evidence of enhanced uric acid clearance in macrohematuric patients with IgA nephropathy: prognostic significance of macrohematuria. ( Miura, M; Nomoto, Y; Sakai, H, 1990)
"We evaluated the association between baseline uric acid and the primary composite outcome of doubling of interstitium or ESRD from interstitial fibrosis and tubular atrophy (IF/TA) in the Angiotensin II Blockade for Chronic Allograft Nephropathy (ABCAN) Trial participants."5.19Uric acid and allograft loss from interstitial fibrosis/tubular atrophy: post hoc analysis from the angiotensin II blockade in chronic allograft nephropathy trial. ( Hart, A; Ibrahim, HN; Jackson, S; Kasiske, BL; Matas, AJ; Mauer, MS; Najafian, B; Spong, R, 2014)
"Among patients with immunoglobulin A nephropathy, the higher levels of fibrinogen and uric acid may mean a higher score of tubular atrophy/interstitial fibrosis, which suggests the renal biopsy should be performed for these patients as early as possible to defined pathological classification, even though there is no obvious abnormal change in the test of renal function."4.12A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score. ( Hu, S; Lou, Z; Tu, M, 2022)
" Blood urea nitrogen (BUN), serum creatinine (Scr), uric acid (UA) and proteinuria were evaluated."3.78Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model. ( He, J; Pei, X; Sun, S; Wang, C; Wang, Y; Wu, J; Yu, M; Zhao, W; Zhu, B, 2012)
"Renal handling of uric acid and clinical prognosis following episodes of macroscopic hematuria (EMH) were examined in 113 patients with IgA nephropathy (IgAN)."3.68Evidence of enhanced uric acid clearance in macrohematuric patients with IgA nephropathy: prognostic significance of macrohematuria. ( Miura, M; Nomoto, Y; Sakai, H, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Tu, M1
Hu, S1
Lou, Z1
Zalewska, A1
Knaś, M1
Gińdzieńska-Sieśkiewicz, E1
Waszkiewicz, N1
Klimiuk, A1
Litwin, K1
Sierakowski, S1
Waszkiel, D1
Hart, A1
Jackson, S1
Kasiske, BL1
Mauer, MS1
Najafian, B1
Matas, AJ1
Spong, R1
Ibrahim, HN1
Ai, Z1
Xu, R1
Liu, W1
Zhou, Q1
Li, B1
Huang, F1
Yu, X1
Yang, Q1
He, J1
Wang, Y1
Sun, S1
Yu, M1
Wang, C1
Pei, X1
Zhu, B1
Wu, J1
Zhao, W1
Farstad, M1
Haug, JO1
Lindbak, H1
Skaug, OE1
VIVIER, G1
THOMAS, J1
Miura, M1
Nomoto, Y1
Sakai, H1
Passwell, J1
Zipperkowski, L1
Katznelson, D1
Szeinberg, A1
Crispin, M1
Pollak, S1
Goodman, R1
Bat-Miriam, M1
Cohen, BE1
Young, IJ1
Crampton, AR1
Shimizu, T1
Hiroata, R1
Nomura, Y1
Aibara, K1
Miyaki, K1
Simon, NM1
Smucker, JE1
O'Conor, VJ1
del Greco, F1

Trials

1 trial available for uric acid and Atrophy

ArticleYear
Uric acid and allograft loss from interstitial fibrosis/tubular atrophy: post hoc analysis from the angiotensin II blockade in chronic allograft nephropathy trial.
    Transplantation, 2014, May-27, Volume: 97, Issue:10

    Topics: Allografts; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atrophy; Biopsy; Chronic Diseas

2014

Other Studies

11 other studies available for uric acid and Atrophy

ArticleYear
A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:1

    Topics: Adult; Atrophy; Female; Fibrinogen; Fibrosis; Glomerulonephritis, IGA; Humans; Kidney Tubules; Male;

2022
Salivary antioxidants in patients with systemic sclerosis.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:1

    Topics: Adult; Aged; Antioxidants; Atrophy; Case-Control Studies; Colorimetry; DMF Index; Female; Fibrosis;

2014
Clinicopathologic features of IgA nephropathy patients with different levels of proteinuria.
    Clinical nephrology, 2016, Volume: 86, Issue:7

    Topics: Adult; Atrophy; Biopsy; Female; Fibrosis; Glomerular Filtration Rate; Glomerulonephritis, IGA; Glome

2016
Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model.
    Nephrology (Carlton, Vic.), 2012, Volume: 17, Issue:5

    Topics: Animals; Atrophy; Biomarkers; Blood Urea Nitrogen; Bone Marrow Transplantation; Cell-Derived Micropa

2012
URIC ACID IN THE CEREBROSPINAL FLUID IN CEREBRAL ATROPHY.
    Acta neurologica Scandinavica, 1965, Volume: 41, Issue:1

    Topics: Atrophy; Blood Chemical Analysis; Brain Diseases; Cerebrospinal Fluid; Humans; Nervous System Diseas

1965
[RENAL ATROPHIES OF URIC LITHIASIS. CIRCUMSTANCES OF APPEARANCE, EVOLUTION OF RADIOLOGICAL STUDY OF 5 CASES].
    Rein et foie, maladies de la nutrition; actualites, 1965, Volume: 7

    Topics: Atrophy; Humans; Kidney; Kidney Calculi; Kidney Diseases; Lithiasis; Pathology; Radiology; Uric Acid

1965
Evidence of enhanced uric acid clearance in macrohematuric patients with IgA nephropathy: prognostic significance of macrohematuria.
    Clinical nephrology, 1990, Volume: 33, Issue:1

    Topics: Adult; Atrophy; Female; Follow-Up Studies; Glomerulonephritis, IGA; Hematuria; Humans; Kidney Functi

1990
A syndrome characterized by congenital ichthyosis with atrophy, mental retardation, dwarfism, and generalized aminoaciduria.
    The Journal of pediatrics, 1973, Volume: 82, Issue:3

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Atrophy; Biopsy; Child; Consanguinity; Dermatoglyp

1973
Cerebrospinal fluid uric acid levels in cerebral atrophy occurring in psychiatric and neurologic patients.
    Biological psychiatry, 1974, Volume: 8, Issue:3

    Topics: Adult; Age Factors; Aged; Alcoholism; Atrophy; Brain Diseases; Female; Hospitalization; Humans; Male

1974
Nephrotoxic effect of MSG (monosodium glutamate) in the chicken.
    Japanese journal of medical science & biology, 1971, Volume: 24, Issue:5

    Topics: Acute Kidney Injury; Animals; Atrophy; Body Weight; Chickens; Edema; Extremities; Gallbladder; Gluta

1971
Differential uric acid excretion in essential and renal hypertension.
    Circulation, 1969, Volume: 39, Issue:1

    Topics: Atrophy; Glomerular Filtration Rate; Humans; Hydronephrosis; Hypertension; Hypertension, Renal; Kidn

1969