Page last updated: 2024-10-20

uric acid and Atrial Remodeling

uric acid has been researched along with Atrial Remodeling in 7 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Atrial Remodeling: Long-term changes in the electrophysiological parameters and/or anatomical structures of the HEART ATRIA that result from prolonged changes in atrial rate, often associated with ATRIAL FIBRILLATION or long periods of intense EXERCISE.

Research Excerpts

ExcerptRelevanceReference
"High levels of serum uric acid is closely associated with atrial fibrillation (AF); nonetheless, the detailed mechanisms remain unknown."4.02Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications. ( Li, Y; Liang, D; Liang, Z; Liu, H; Liu, Y; Su, M; Sun, L; Wang, D; Wei, Y; Yin, S; Zhang, G; Zhang, S; Zhao, J, 2021)
"Serum uric acid levels were not significantly different in the asymptomatic hyperuricaemia, gouty arthritis without tophi and gouty tophi groups."3.80The effects of gout on left atrial volume remodelling: a prospective echocardiographic study. ( Chang, PJ; Chang, ST; Chen, MC; Chung, CM; Hsiao, JF; Lin, CL; Lin, JC; Pan, KL, 2014)
"We studied 62 patients with untreated hypertension, randomly assigned to cilnidipine or amlodipine for 48 weeks."2.82Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients. ( Eguchi, A; Fujiwara, S; Hirotani, S; Komamura, K; Koshiba, M; Mano, T; Masaki, M; Masuyama, T; Sugahara, M; Tsujino, T, 2016)
"Hyperuricemia has been widely accepted to be associated with the incidence of paroxysmal or persistent AF, as well as to the risk of AF in post cardiovascular surgery patients."2.53Hyperuricemia and Atrial Fibrillation. ( Hisatome, I; Kuwabara, M; Maharani, N, 2016)
"Gout is usually found in patients with atrial fibrillation (AF)."1.72Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes. ( Higaki, K; Hisatome, I; Kurata, Y; Kuwabara, M; Lanaspa, MA; Li, P; Ninomiya, H; Shirayoshi, Y; Taufiq, F; Tsuneto, M, 2022)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Li, P1
Kurata, Y1
Taufiq, F1
Kuwabara, M2
Ninomiya, H1
Higaki, K1
Tsuneto, M1
Shirayoshi, Y1
Lanaspa, MA1
Hisatome, I2
Wang, D1
Sun, L1
Zhang, G1
Liu, Y1
Liang, Z1
Zhao, J1
Yin, S1
Su, M1
Zhang, S1
Wei, Y1
Liu, H1
Liang, D1
Li, Y1
Vrachatis, DA1
Papathanasiou, KA1
Iliodromitis, KE1
Giotaki, SG1
Kossyvakis, C1
Raisakis, K1
Kaoukis, A1
Lambadiari, V1
Avramides, D1
Reimers, B1
Stefanini, GG1
Cleman, M1
Giannopoulos, G1
Lansky, A1
Deftereos, SG1
Ferron, AJT1
Francisqueti, FV1
Minatel, IO1
Silva, CCVA1
Bazan, SGZ1
Kitawara, KAH1
Garcia, JL1
CorrĂȘa, CR1
Moreto, F1
Ferreira, ALA1
Pan, KL1
Lin, JC1
Lin, CL1
Chen, MC1
Chang, PJ1
Hsiao, JF1
Chang, ST1
Chung, CM1
Masaki, M1
Mano, T1
Eguchi, A1
Fujiwara, S1
Sugahara, M1
Hirotani, S1
Tsujino, T1
Komamura, K1
Koshiba, M1
Masuyama, T1
Maharani, N1

Reviews

2 reviews available for uric acid and Atrial Remodeling

ArticleYear
Could Sodium/Glucose Co-Transporter-2 Inhibitors Have Antiarrhythmic Potential in Atrial Fibrillation? Literature Review and Future Considerations.
    Drugs, 2021, Volume: 81, Issue:12

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Remodeling; Diabetes Mellitus, Type 2; Energy Me

2021
Hyperuricemia and Atrial Fibrillation.
    International heart journal, 2016, Jul-27, Volume: 57, Issue:4

    Topics: Antioxidants; Atrial Fibrillation; Atrial Remodeling; Evidence-Based Medicine; Humans; Hyperuricemia

2016

Trials

1 trial available for uric acid and Atrial Remodeling

ArticleYear
Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients.
    Heart and vessels, 2016, Volume: 31, Issue:11

    Topics: Amlodipine; Atrial Function, Left; Atrial Remodeling; Biomarkers; Blood Pressure; Calcium Channel Bl

2016

Other Studies

4 other studies available for uric acid and Atrial Remodeling

ArticleYear
Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes.
    Molecular biology reports, 2022, Volume: 49, Issue:7

    Topics: Animals; Atrial Remodeling; Caspase 1; Gout; Humans; Inflammasomes; Interleukin-1beta; Kv1.5 Potassi

2022
Increased Susceptibility of Atrial Fibrillation Induced by Hyperuricemia in Rats: Mechanisms and Implications.
    Cardiovascular toxicology, 2021, Volume: 21, Issue:3

    Topics: Actins; Animals; Apoptosis; Atrial Fibrillation; Atrial Remodeling; bcl-2-Associated X Protein; Benz

2021
Association between Cardiac Remodeling and Metabolic Alteration in an Experimental Model of Obesity Induced by Western Diet.
    Nutrients, 2018, Nov-05, Volume: 10, Issue:11

    Topics: Animals; Atrial Remodeling; Blood Glucose; Blood Pressure; Body Weight; Cardiovascular Diseases; Cho

2018
The effects of gout on left atrial volume remodelling: a prospective echocardiographic study.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:5

    Topics: Adult; Aged; Arthritis, Gouty; Atrial Remodeling; Cardiac Volume; Case-Control Studies; Cross-Sectio

2014