Page last updated: 2024-10-20

uric acid and Atherosclerosis

uric acid has been researched along with Atherosclerosis in 142 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.

Research Excerpts

ExcerptRelevanceReference
"The European Lacidipine Study on Atherosclerosis (ELSA) was a randomized, double-blind, multicenter trial comparing the effects of a 4-year treatment with either lacidipine or atenolol on progression of carotid atherosclerosis in patients with moderate hypertension."9.30Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis. ( Bombelli, M; Cuspidi, C; Facchetti, R; Grassi, G; Macchiarulo, M; Maggiolini, D; Mancia, G; Parati, G, 2019)
"The aim of this study was to investigate the long-term effective control of serum uric acid by allopurinol on the carotid intima-media thickness (IMT) in patients with type 2 diabetes (T2DM) and asymptomatic hyperuricemia (HUA)."9.20The Effects of Allopurinol on the Carotid Intima-media Thickness in Patients with Type 2 Diabetes and Asymptomatic Hyperuricemia: A Three-year Randomized Parallel-controlled Study. ( Chen, Y; Liu, P; Wang, D; Wang, H; Wang, Y; Zhang, F, 2015)
" Elevated uric acid levels are risk factors for gout, hypertension, and chronic kidney diseases."9.12Uric Acid in Inflammation and the Pathogenesis of Atherosclerosis. ( Kimura, Y; Kono, H; Tsukui, D, 2021)
"The mechanisms of hyperhomocysteinemia (HHcy) and hyperuricemia (HUA) that promote atherosclerosis were seldom explored and always indefinite."8.95Role of Hyperhomocysteinemia and Hyperuricemia in Pathogenesis of Atherosclerosis. ( Chen, H; Chen, J; Gu, Y; Liu, N; Yang, K; Zhao, J, 2017)
"The relationship between elevated serum uric acid level and metabolic syndrome (MS) has been debated."8.90Association of serum uric acid and metabolic syndrome in type 2 diabetes. ( Bonakdaran, S; Kharaqani, B, 2014)
" Serum uric acid levels were measured and arterial stiffness and atherosclerosis were assessed by the cardio-ankle vascular index (CAVI), carotid intima-media thickness (IMT), and plaque, using ultrasound imaging."8.12Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females. ( Dohi, Y; Iwase, M; Nagami, T; Ohte, N; Seo, Y; Sugiura, T; Suzuki, K; Takagi, Y; Takase, H; Tomiishi, T; Yokochi, T; Yoshikane, N, 2022)
"Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with atherosclerosis, respectively."8.12Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. ( Dong, H; Hu, X; Li, G; Li, W; Liu, J; Wang, C; Zhou, Y, 2022)
"The association between serum uric acid (UA) and atherosclerosis in old people is controversial."8.02Association between uric acid and atherosclerosis in community-dwelling older people: The SONIC study. ( Akagi, Y; Akasaka, H; Arai, Y; Godai, K; Gondo, Y; Ikebe, K; Ishizaki, T; Kabayama, M; Kamide, K; Kiyoshige, E; Masui, Y; Rakugi, H; Sekiguchi, T; Sugimoto, K; Takami, Y; Takeya, Y; Tanaka, K; Yamamoto, K; Yasumoto, S, 2021)
"We aimed to reveal the relationship of serum uric acid (SUA) with monocyte-high-density lipoprotein ratio (MHR) and other inflammatory markers in acne patients before and after isotretinoin treatment."8.02Increases in uric acid and monocyte-high-density lipoprotein ratio as possible atherosclerotic indicators in acne patients using isotretinoin. ( Metin, N; Turan, Ç, 2021)
"Uric acid is supposed but not yet determined to be associated with atherosclerosis."7.96Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. ( Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T, 2020)
"Elevated serum uric acid (SUA) is associated with cardiovascular risk factors, which often contribute to dementia and dementia-like morbidity, yet several cross-sectional studies have shown protective associations with cognition, which would be consistent with other work showing benefits of elevated SUA through its antioxidant properties."7.96Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort. ( Alam, AB; Alonso, A; Power, MC; West, NA; Wu, A, 2020)
"The study aimed to determine the relationship among serum uric acid and metabolic syndrome and atherosclerosis, by means of carotid intima media-thickness, in a cohort of 811 otherwise healthy overweight/obese subjects, without overt atherosclerosis not using any kind of drug."7.88Uric Acid, Metabolic Syndrome and Atherosclerosis: The Chicken or the Egg, Which Comes First? ( Caccavo, D; Carbonara, R; Ciccone, MM; Cortese, AM; Cortese, F; De Pergola, G; Masiello, M; Meliota, G; Silvestris, F; Termine, G, 2018)
"Allantoin is the main product of uric acid oxidation and was found to be augmented in atherosclerotic plaque in human autopsy and in animal models of atherosclerosis."7.88Allantoin as an independent marker associated with carotid intima-media thickness in subclinical atherosclerosis. ( Benseãor, IM; Lotufo, PA; Meotti, FC; Nascimento, KP; Santana, MS, 2018)
"This paper aims to evaluate the association between serum uric acid (SUA) levels, arterial hypertension (HT) prevalence, blood pressure values control, kidney function and intima media thickness (IMT), as a surrogate marker of early atherosclerosis, in a representative group of Romanian adult population."7.88Serum uric acid and arterial hypertension-Data from Sephar III survey. ( Buzas, R; Dorobantu, M; Ivan, V; Lighezan, D; Tautu, OF, 2018)
"Aim To determine the relationship of homocysteine (HCY), uric acid (UA) and C-reactive protein (CRP) in serum of patients with acute myocardial infarction (AMI) prior to application of percutaneous coronary intervention (PCI) and their level of correlation in serum of patients with normal and elevated CRP (predictor of worse cardiovascular outcomes)."7.88A relation of serum homocysteine, uric acid and C-reactive protein level in patients with acute myocardial infarction. ( Brizić, I; Čaušević, A; Jelić Knezović, N; Marković Boras, M; Mikulić, I; Vasilj, M, 2018)
"Uric acid is a molecule that is known to act as a natural antioxidant in acute oxidative stress conditions such as acute ischemic stroke (AIS)."7.88Can high uric acid levels be an independent risk factor for acute ischemic stroke due to large-artery atherosclerosis? ( Acar, AB; Acar, T; Gül, SS; Güzey Aras, Y, 2018)
"We indicated that uric acid, AIP, and proteinuria are closely related."7.88Relationship Between Uric Acid, Proteinuria, and Atherogenic Index of Plasma in Renal Transplant Patients. ( Biyik, Z; Guney, I, 2018)
" Whether gout, the most common rheumatologic inflammatory arthritis, or its cause, elevated serum uric acid (SUA), is associated with VTE incidence is unknown."7.83Serum uric acid, gout, and venous thromboembolism: The atherosclerosis risk in communities study. ( Folsom, AR; Kubota, Y; McAdams-DeMarco, M, 2016)
"Serum uric acid (SUA) is associated with many cardiovascular risk factors such as hypertension (HTN) and metabolic syndrome (MetS)."7.81Serum uric acid levels are associated with hypertension and metabolic syndrome but not atherosclerosis in Chinese inpatients with type 2 diabetes. ( Bao, YQ; Dong, XH; Jia, WP; Li, LX; Li, MF; Li, TT; Shen, J; Zhang, R, 2015)
"The aim of this study was to examine the association between uric acid (UA) level during pregnancy and future maternal hospitalization for atherosclerotic-related morbidity."7.81High Uric Acid Levels During Pregnancy Linked to Increased Risk for Future Atherosclerotic-Related Hospitalization. ( Sergienko, R; Sheiner, E; Shoham-Vardi, I; Wolak, T, 2015)
"Male rabbits (n = 48) were divided into control, hyperuricemia (HU), hypercholesterolemia + hyperuricemia (HC + HU) and high-purine with 30-mg/kg/d losartan (HU + losartan) groups."7.81Losartan alleviates hyperuricemia-induced atherosclerosis in a rabbit model. ( Ding, Y; Li, N; Miao, P; Zheng, H, 2015)
"Serum uric acid (SUA) levels correlate with many recognized cardiovascular risk factors, including age, male sex, hypertension, diabetes mellitus, hypertriglyceridemia, obesity, and insulin resistance."7.80Association between serum uric acid, hypertension, vascular stiffness and subclinical atherosclerosis: data from the Brisighella Heart Study. ( Borghi, C; Cicero, AF; D'Addato, S; Rosticci, M; Salvi, P, 2014)
"The aims of this study were to investigate (i) associations between uric acid and prevalent cardiovascular disease (CVD), ankle-arm blood pressure index (AAIx) and carotid intima-media thickness (CIMT) in the total population and in predefined subgroups according to glucose metabolism status and (ii) the extent to which these associations are explained by low-grade inflammation."7.80The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study. ( Arts, IC; Boonen, A; Dagnelie, PC; Ferreira, I; Feskens, EJ; Schalkwijk, CG; Stehouwer, CD; van der Kallen, CJ; van der Linden, S; van Greevenbroek, MM; Wijnands, JM, 2014)
"Uric acid and hsCRP levels are independently and positively associated with subclinical thoracic atherosclerosis."7.79Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis. ( Çaylı, M; Elbasan, Z; Gür, M; Kalkan, GY; Kaya, Z; Özaltun, B; Sahin, DY; Yıldız, A, 2013)
"Serum uric acid (SUA) is a potential risk factor for atherosclerosis."7.78Serum uric acid: a marker of metabolic syndrome and subclinical atherosclerosis in Korean men. ( Bian, L; Choi, Y; Zhang, Z, 2012)
"Serum uric acid is a predictor of cardiac events and correlates to N-terminal pro-B-type natriuretic peptide and albuminuria, underscoring the importance of uric acid as a cardiovascular risk marker in patients with diabetes."7.78Serum uric acid is related to cardiovascular events and correlates with N-terminal pro-B-type natriuretic peptide and albuminuria in patients with diabetes mellitus. ( Clodi, M; Hülsmann, M; Kromoser, H; Luger, A; Neuhold, S; Pacher, R; Prager, R; Resl, M; Riedl, M; Strunk, G; Vila, G, 2012)
"Serum uric acid (SUA) is a suggested biomarker for established coronary artery disease, but the role of SUA in early phases of atherosclerosis is controversial."7.78Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study. ( Hutri-Kähönen, N; Huupponen, R; Jula, A; Juonala, M; Kähönen, M; Lehtimäki, T; Loo, BM; Lyytikäinen, LP; Oikonen, M; Raitakari, OT; Saarikoski, L; Seppälä, I; Siitonen, N; Viikari, JS; Wendelin-Saarenhovi, M, 2012)
"In PsA patients without clinically evident CV disease there is a correlation between serum uric acid concentration and subclinical atherosclerosis."7.75Asymptomatic hyperuricemia and serum uric acid concentration correlate with subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease. ( Gomez-Acebo, I; Gonzalez-Gay, MA; Gonzalez-Juanatey, C; Llorca, J; Martin, J; Miranda-Filloy, JA; Paz-Carreira, J; Vazquez-Rodriguez, TR, 2009)
" The aim of this study was to evaluate the relationships between serum uric acid concentration and degree of urinary albumin excretion as well as markers of subclinical atherosclerosis in men with type 2 diabetes mellitus."7.74Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitus. ( Asano, M; Fukui, M; Harusato, I; Hasegawa, G; Hosoda, H; Kadono, M; Nakamura, N; Shiraishi, E; Tanaka, M; Yoshikawa, T, 2008)
"Serum uric acid has been positively associated with incident hypertension, but previous studies have had limited ability to explore this relationship across sex and ethnic strata."7.73Serum uric acid predicts incident hypertension in a biethnic cohort: the atherosclerosis risk in communities study. ( Bleyer, AJ; Erlinger, TP; Evans, GW; Herrington, DM; Mellen, PB; Nieto, FJ; Wagenknecht, LE; Wofford, MR, 2006)
"Hyperuricemia is associated with the activation of the Nod-like receptor protein 3 inflammasome."7.30C-reactive Protein Levels and Cardiovascular Outcomes After Febuxostat Treatment in Patients with Asymptomatic Hyperuricemia: Post-hoc Analysis of a Randomized Controlled Study. ( Hayashi, T; Hiramitsu, S; Hisatome, I; Jinnouchi, H; Kakuda, H; Kawai, N; Kimura, K; Kojima, S; Matsui, K; Mori, H; Ogawa, H; Ohya, Y; Saito, Y; Sugawara, M; Tokutake, E; Tsujita, K; Uchiyama, K; Wakasa, Y; Waki, M; Yokota, N, 2023)
"Insulin resistance was assessed by the homeostatic model assessment (HOMA) index."5.56Uric Acid and Vascular Damage in Essential Hypertension: Role of Insulin Resistance. ( Andreozzi, F; Armentaro, G; Cassano, V; Crescibene, D; Hribal, ML; Magurno, M; Maio, R; Miceli, S; Pelaia, C; Perticone, F; Perticone, M; Sciacqua, A; Sesti, G; Toscani, A, 2020)
"The cumulative incidence of vascular stenosis was significantly higher in subjects with hyperuricaemia than in those without hyperuricaemia (54."5.51Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis. ( Chen, J; Cheng, W; Cui, Q; Geng, B; Li, N; Song, M; Wang, K; Wang, Y; Yang, J; Yao, Y; Zhou, Y, 2019)
"Hyperuricemia is an independent predictor for early atherosclerosis in hypertensive subjects with normal renal function."5.38Uric acid is an important predictor for hypertensive early atherosclerosis. ( Bahadir, E; Citil, R; Deger, SM; Durmaz, AO; Mutluay, R; Sindel, S, 2012)
"Hyperuricaemia was associated with cardiac hypertrophy with an odds ratio (OR) of 1."5.36Role of uric acid in the link between arterial stiffness and cardiac hypertrophy: a cross-sectional study. ( Chen, CC; Chen, HW; Hung, KC; Hwang, JS; Ko, YS; Kuo, CF; Lin, CM; Lin, YS; Luo, SF; See, LC; Shen, YM; Tseng, WY; Wen, MS; Yu, KH, 2010)
"The European Lacidipine Study on Atherosclerosis (ELSA) was a randomized, double-blind, multicenter trial comparing the effects of a 4-year treatment with either lacidipine or atenolol on progression of carotid atherosclerosis in patients with moderate hypertension."5.30Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis. ( Bombelli, M; Cuspidi, C; Facchetti, R; Grassi, G; Macchiarulo, M; Maggiolini, D; Mancia, G; Parati, G, 2019)
"Hyperuricemia is caused by reduced renal/extrarenal excretion and overproduction of uric acid."5.22Impact of hyperuricemia on chronic kidney disease and atherosclerotic cardiovascular disease. ( Maeda, N; Nishizawa, H; Shimomura, I, 2022)
" A total of 500 patients with asymptomatic hyperuricemia (uric acid >7."5.22Rationale and design of a multicenter randomized study for evaluating vascular function under uric acid control using the xanthine oxidase inhibitor, febuxostat: the PRIZE study. ( Ako, J; Bando, YK; Eguchi, K; Higashi, Y; Inoue, T; Ishizaka, N; Ishizu, T; Kanzaki, Y; Kuroyanagi, T; Maemura, K; Murohara, T; Node, K; Ohishi, M; Oyama, J; Sata, M; Sato, Y; Taguchi, I; Tanaka, A; Teragawa, H; Tomiyama, H; Ueda, S; Yamada, H, 2016)
"The aim of this study was to investigate the long-term effective control of serum uric acid by allopurinol on the carotid intima-media thickness (IMT) in patients with type 2 diabetes (T2DM) and asymptomatic hyperuricemia (HUA)."5.20The Effects of Allopurinol on the Carotid Intima-media Thickness in Patients with Type 2 Diabetes and Asymptomatic Hyperuricemia: A Three-year Randomized Parallel-controlled Study. ( Chen, Y; Liu, P; Wang, D; Wang, H; Wang, Y; Zhang, F, 2015)
" Elevated uric acid levels are risk factors for gout, hypertension, and chronic kidney diseases."5.12Uric Acid in Inflammation and the Pathogenesis of Atherosclerosis. ( Kimura, Y; Kono, H; Tsukui, D, 2021)
"The role of uric acid (UA) in the process of atherothrombosis is controversial."5.12Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 years. ( Bandinelli, S; Cherubini, A; Ferrucci, L; Lauretani, F; Maggio, M; Miller, E; Najjar, SS; Ruggiero, C; Senin, U, 2007)
" Based on preclinical and clinical evidences, this review discusses: (i) stone forming risk factors, crystal nucleation, aggregation, injury-induced crystal retention, and stone formation, (ii) CVD risk factors such as dyslipidemia, perturbation of gut microbiome, obesity, free radical-induced lipoprotein oxidation, and retention in the arterial wall, subsequent foam cell formation, and atherosclerosis, (iii) mechanism by which stone forming risk factors such as oxalate, calcium, uric acid, and infection contribute toward CVDs, and (iv) how CVD risk factors, such as cholesterol, phospholipids, and uric acid, contribute to kidney stone formation are described."4.98Cross-talk between renal lithogenesis and atherosclerosis: an unveiled link between kidney stone formation and cardiovascular diseases. ( Devarajan, A, 2018)
"The mechanisms of hyperhomocysteinemia (HHcy) and hyperuricemia (HUA) that promote atherosclerosis were seldom explored and always indefinite."4.95Role of Hyperhomocysteinemia and Hyperuricemia in Pathogenesis of Atherosclerosis. ( Chen, H; Chen, J; Gu, Y; Liu, N; Yang, K; Zhao, J, 2017)
"The relationship between elevated serum uric acid level and metabolic syndrome (MS) has been debated."4.90Association of serum uric acid and metabolic syndrome in type 2 diabetes. ( Bonakdaran, S; Kharaqani, B, 2014)
"Overall, the XO inhibitor febuxostat exerted protective effects against NASH and atherosclerosis in SHRSP5/Dmcr rats."4.31Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats. ( Fujii, M; Fukuoka, T; Hirohata, S; Honma, K; Kakimoto, M; Kirihara, S; Kitamori, K; Nakayama, H; Ran, S; Sato, I; Watanabe, S; Yamamoto, S, 2023)
" Serum uric acid levels were measured and arterial stiffness and atherosclerosis were assessed by the cardio-ankle vascular index (CAVI), carotid intima-media thickness (IMT), and plaque, using ultrasound imaging."4.12Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females. ( Dohi, Y; Iwase, M; Nagami, T; Ohte, N; Seo, Y; Sugiura, T; Suzuki, K; Takagi, Y; Takase, H; Tomiishi, T; Yokochi, T; Yoshikane, N, 2022)
"Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with atherosclerosis, respectively."4.12Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. ( Dong, H; Hu, X; Li, G; Li, W; Liu, J; Wang, C; Zhou, Y, 2022)
"The association between serum uric acid (UA) and atherosclerosis in old people is controversial."4.02Association between uric acid and atherosclerosis in community-dwelling older people: The SONIC study. ( Akagi, Y; Akasaka, H; Arai, Y; Godai, K; Gondo, Y; Ikebe, K; Ishizaki, T; Kabayama, M; Kamide, K; Kiyoshige, E; Masui, Y; Rakugi, H; Sekiguchi, T; Sugimoto, K; Takami, Y; Takeya, Y; Tanaka, K; Yamamoto, K; Yasumoto, S, 2021)
"We aimed to reveal the relationship of serum uric acid (SUA) with monocyte-high-density lipoprotein ratio (MHR) and other inflammatory markers in acne patients before and after isotretinoin treatment."4.02Increases in uric acid and monocyte-high-density lipoprotein ratio as possible atherosclerotic indicators in acne patients using isotretinoin. ( Metin, N; Turan, Ç, 2021)
"Uric acid is supposed but not yet determined to be associated with atherosclerosis."3.96Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. ( Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T, 2020)
"Elevated serum uric acid (SUA) is associated with cardiovascular risk factors, which often contribute to dementia and dementia-like morbidity, yet several cross-sectional studies have shown protective associations with cognition, which would be consistent with other work showing benefits of elevated SUA through its antioxidant properties."3.96Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort. ( Alam, AB; Alonso, A; Power, MC; West, NA; Wu, A, 2020)
"This study investigated the association of serum uric acid (UA) with carotid fluoro-2-deoxyglucose (FDG) uptake as a marker of inflammatory atherosclerosis."3.96Serum uric acid in asymptomatic adults is weakly associated with carotid artery FDG uptake but not intima-media thickness. ( Bae, JH; Cho, YS; Choi, JY; Hyun, SH; Kim, BT; Lee, KH; Moon, SH, 2020)
"The study aimed to determine the relationship among serum uric acid and metabolic syndrome and atherosclerosis, by means of carotid intima media-thickness, in a cohort of 811 otherwise healthy overweight/obese subjects, without overt atherosclerosis not using any kind of drug."3.88Uric Acid, Metabolic Syndrome and Atherosclerosis: The Chicken or the Egg, Which Comes First? ( Caccavo, D; Carbonara, R; Ciccone, MM; Cortese, AM; Cortese, F; De Pergola, G; Masiello, M; Meliota, G; Silvestris, F; Termine, G, 2018)
"Allantoin is the main product of uric acid oxidation and was found to be augmented in atherosclerotic plaque in human autopsy and in animal models of atherosclerosis."3.88Allantoin as an independent marker associated with carotid intima-media thickness in subclinical atherosclerosis. ( Benseãor, IM; Lotufo, PA; Meotti, FC; Nascimento, KP; Santana, MS, 2018)
"This paper aims to evaluate the association between serum uric acid (SUA) levels, arterial hypertension (HT) prevalence, blood pressure values control, kidney function and intima media thickness (IMT), as a surrogate marker of early atherosclerosis, in a representative group of Romanian adult population."3.88Serum uric acid and arterial hypertension-Data from Sephar III survey. ( Buzas, R; Dorobantu, M; Ivan, V; Lighezan, D; Tautu, OF, 2018)
"Aim To determine the relationship of homocysteine (HCY), uric acid (UA) and C-reactive protein (CRP) in serum of patients with acute myocardial infarction (AMI) prior to application of percutaneous coronary intervention (PCI) and their level of correlation in serum of patients with normal and elevated CRP (predictor of worse cardiovascular outcomes)."3.88A relation of serum homocysteine, uric acid and C-reactive protein level in patients with acute myocardial infarction. ( Brizić, I; Čaušević, A; Jelić Knezović, N; Marković Boras, M; Mikulić, I; Vasilj, M, 2018)
"Uric acid is a molecule that is known to act as a natural antioxidant in acute oxidative stress conditions such as acute ischemic stroke (AIS)."3.88Can high uric acid levels be an independent risk factor for acute ischemic stroke due to large-artery atherosclerosis? ( Acar, AB; Acar, T; Gül, SS; Güzey Aras, Y, 2018)
"We indicated that uric acid, AIP, and proteinuria are closely related."3.88Relationship Between Uric Acid, Proteinuria, and Atherogenic Index of Plasma in Renal Transplant Patients. ( Biyik, Z; Guney, I, 2018)
"Hyperuricemia and angiotensin II (Ang II) may have a pathogenetic role in the development of hypertension and atherosclerosis as well as cardiovascular disease (CVD) and its prognosis."3.85Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ. ( Çetin, A; Kırça, M; Oğuz, N; Uzuner, F; Yeşilkaya, A, 2017)
" Correlations between SA and atherosclerosis indicators, such as CIMT, LDL, hs-CRP, and uric acid, in hypothyroid individuals suggest that SA may be an indicator of atherogenesis in these patients."3.85Serum Total Sialic Acid Level is Elevated in Hypothyroid Patients as an Atherosclerotic Risk Factor. ( Aktürk, M; Altay, M; Arslan, M; Ateş, İ; Bukan, N; Çakır, N; Cerit, ET; Karakoç, MA; Yılmaz Demirtaş, C, 2017)
"Atherosclerosis induces the elevation of uric acid (UA), and an elevated UA level is well known to lead to a poor prognosis in patients with acute heart failure (AHF)."3.85Are atherosclerotic risk factors associated with a poor prognosis in patients with hyperuricemic acute heart failure? The evaluation of the causal dependence of acute heart failure and hyperuricemia. ( Asai, K; Hata, N; Kobayashi, N; Matsushita, M; Nishigoori, S; Okazaki, H; Shibata, Y; Shibuya, J; Shimizu, W; Shinada, T; Shiomura, R; Shirakabe, A; Yamamoto, Y, 2017)
"We previously identified substantial laboratory drift in uric acid measurements in the Atherosclerosis Risk in Communities (ARIC) Study over time."3.83Iterative Outlier Removal: A Method for Identifying Outliers in Laboratory Recalibration Studies. ( Coresh, J; Couper, D; Eckfeldt, JH; Grams, ME; Li, D; Parrinello, CM; Sang, Y; Selvin, E; Wruck, LM, 2016)
" Whether gout, the most common rheumatologic inflammatory arthritis, or its cause, elevated serum uric acid (SUA), is associated with VTE incidence is unknown."3.83Serum uric acid, gout, and venous thromboembolism: The atherosclerosis risk in communities study. ( Folsom, AR; Kubota, Y; McAdams-DeMarco, M, 2016)
"Serum uric acid (SUA) is associated with many cardiovascular risk factors such as hypertension (HTN) and metabolic syndrome (MetS)."3.81Serum uric acid levels are associated with hypertension and metabolic syndrome but not atherosclerosis in Chinese inpatients with type 2 diabetes. ( Bao, YQ; Dong, XH; Jia, WP; Li, LX; Li, MF; Li, TT; Shen, J; Zhang, R, 2015)
"The aim of this study was to examine the association between uric acid (UA) level during pregnancy and future maternal hospitalization for atherosclerotic-related morbidity."3.81High Uric Acid Levels During Pregnancy Linked to Increased Risk for Future Atherosclerotic-Related Hospitalization. ( Sergienko, R; Sheiner, E; Shoham-Vardi, I; Wolak, T, 2015)
"The results show that mood disorders, TUD and BMI together with elevated levels of uric acid and MDA independently contribute to increased atherogenic potential, while BMI and uric acid are risk factors for insulin resistance."3.81Factors influencing insulin resistance in relation to atherogenicity in mood disorders, the metabolic syndrome and tobacco use disorder. ( Barbosa, DS; Berk, M; Bortolasci, CC; de Castro, MR; de Melo, LG; Dodd, S; Maes, M; Moreira, EG; Vargas Nunes, SO; Vargas, HO, 2015)
"Male rabbits (n = 48) were divided into control, hyperuricemia (HU), hypercholesterolemia + hyperuricemia (HC + HU) and high-purine with 30-mg/kg/d losartan (HU + losartan) groups."3.81Losartan alleviates hyperuricemia-induced atherosclerosis in a rabbit model. ( Ding, Y; Li, N; Miao, P; Zheng, H, 2015)
"Serum uric acid (SUA) levels correlate with many recognized cardiovascular risk factors, including age, male sex, hypertension, diabetes mellitus, hypertriglyceridemia, obesity, and insulin resistance."3.80Association between serum uric acid, hypertension, vascular stiffness and subclinical atherosclerosis: data from the Brisighella Heart Study. ( Borghi, C; Cicero, AF; D'Addato, S; Rosticci, M; Salvi, P, 2014)
"In the univariate analysis, the major risk factors for kidney dysfunction in the patients with the cardio-cerebrovascular disease were age, gender, hypertension, diabetes mellitus, dyslipidemia and serum uric acid."3.80High prevalence and risk factors for kidney dysfunction in patients with atherosclerotic cardio-cerebrovascular disease. ( Bao, YS; Ji, Y; Jia, XB; Na, SP; Yang, J; Zhao, SL, 2014)
"Increased serum uric acid levels and vascular atherosclerosis are very common in diabetes."3.80Serum uric acid is associated with arterial stiffness in men with newly diagnosed type 2 diabetes mellitus. ( Sun, H; Xiang, G; Xiang, L; Zhang, J, 2014)
"The aims of this study were to investigate (i) associations between uric acid and prevalent cardiovascular disease (CVD), ankle-arm blood pressure index (AAIx) and carotid intima-media thickness (CIMT) in the total population and in predefined subgroups according to glucose metabolism status and (ii) the extent to which these associations are explained by low-grade inflammation."3.80The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study. ( Arts, IC; Boonen, A; Dagnelie, PC; Ferreira, I; Feskens, EJ; Schalkwijk, CG; Stehouwer, CD; van der Kallen, CJ; van der Linden, S; van Greevenbroek, MM; Wijnands, JM, 2014)
"There was direct relationship between level of CV risk and presence of additional risk factors (hyperglycemia, hyperuricemia, hyperfibrinogenemia, left ventricular hypertrophy)."3.80[Detection of early markers of atherosclerosis in men with various levels of risk of cardiovascular complications]. ( Badeĭnikova, KK; Didigova, RT; Mamedov, MN; Mazaev, AP; Toguzova, ZA, 2014)
"The non-traditional risk factors for atherosclerotic lesions of the cardiovascular system (C-reactive protein, uric acid, fibrinogen, homocysteine) in blood plasma of patients with manifestative hypothyroidism at the age of 23 to 73 years were assessed in the study."3.79[Atypical risk factors of atherosclerosis in patients with hypothyroidism]. ( Mykhaĭlenko, OIu, 2013)
"Uric acid and hsCRP levels are independently and positively associated with subclinical thoracic atherosclerosis."3.79Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis. ( Çaylı, M; Elbasan, Z; Gür, M; Kalkan, GY; Kaya, Z; Özaltun, B; Sahin, DY; Yıldız, A, 2013)
"Serum uric acid (SUA) is a potential risk factor for atherosclerosis."3.78Serum uric acid: a marker of metabolic syndrome and subclinical atherosclerosis in Korean men. ( Bian, L; Choi, Y; Zhang, Z, 2012)
"Serum uric acid is a predictor of cardiac events and correlates to N-terminal pro-B-type natriuretic peptide and albuminuria, underscoring the importance of uric acid as a cardiovascular risk marker in patients with diabetes."3.78Serum uric acid is related to cardiovascular events and correlates with N-terminal pro-B-type natriuretic peptide and albuminuria in patients with diabetes mellitus. ( Clodi, M; Hülsmann, M; Kromoser, H; Luger, A; Neuhold, S; Pacher, R; Prager, R; Resl, M; Riedl, M; Strunk, G; Vila, G, 2012)
"We investigated the relationship among serum cardiac biomarkers including N-terminal pro-brain natriuretic peptide (NT-pro-BNP), cardiac troponin T (cTnT), uric acid and high-sensitive C-reactive protein (hs-CRP) and noninvasive predictors of atherosclerosis including carotid intima-media thickness (IMT), aortic stiffness (pulse wave velocity (PWV)) and transthoracic coronary flow reserve (CFR) in peritoneal dialysis (PD) patients."3.78Cardiac biomarkers and noninvasive predictors of atherosclerosis in chronic peritoneal dialysis patients. ( Akagun, T; Alpay, N; Bozfakioglu, S; Caliskan, Y; Ecder, T; Guz, G; Ozkok, A; Polat, N; Tufan, F, 2012)
"Serum uric acid (SUA) is a suggested biomarker for established coronary artery disease, but the role of SUA in early phases of atherosclerosis is controversial."3.78Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study. ( Hutri-Kähönen, N; Huupponen, R; Jula, A; Juonala, M; Kähönen, M; Lehtimäki, T; Loo, BM; Lyytikäinen, LP; Oikonen, M; Raitakari, OT; Saarikoski, L; Seppälä, I; Siitonen, N; Viikari, JS; Wendelin-Saarenhovi, M, 2012)
"High serum uric acid levels are associated with gout, atherosclerosis and cardiovascular disease."3.76Sex and age interaction with genetic association of atherogenic uric acid concentrations. ( Adams, TD; Brandstätter, A; Coassin, S; Hunt, SC; Kedenko, L; Kiechl, S; Kramer, F; Kronenberg, F; Lamina, C; Paulweber, B; Summerer, M; Willeit, J, 2010)
"In PsA patients without clinically evident CV disease there is a correlation between serum uric acid concentration and subclinical atherosclerosis."3.75Asymptomatic hyperuricemia and serum uric acid concentration correlate with subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease. ( Gomez-Acebo, I; Gonzalez-Gay, MA; Gonzalez-Juanatey, C; Llorca, J; Martin, J; Miranda-Filloy, JA; Paz-Carreira, J; Vazquez-Rodriguez, TR, 2009)
" The aim of this study was to evaluate the relationships between serum uric acid concentration and degree of urinary albumin excretion as well as markers of subclinical atherosclerosis in men with type 2 diabetes mellitus."3.74Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitus. ( Asano, M; Fukui, M; Harusato, I; Hasegawa, G; Hosoda, H; Kadono, M; Nakamura, N; Shiraishi, E; Tanaka, M; Yoshikawa, T, 2008)
"The role of uric acid (UA) in the process of atherosclerosis and atherotrombosis is controversial."3.73Uric acid and inflammatory markers. ( Bandinelli, S; Ble, A; Bos, AJ; Cherubini, A; Dixit, VD; Ferrucci, L; Lauretani, F; Maggio, M; Ruggiero, C; Senin, U, 2006)
"Serum uric acid has been positively associated with incident hypertension, but previous studies have had limited ability to explore this relationship across sex and ethnic strata."3.73Serum uric acid predicts incident hypertension in a biethnic cohort: the atherosclerosis risk in communities study. ( Bleyer, AJ; Erlinger, TP; Evans, GW; Herrington, DM; Mellen, PB; Nieto, FJ; Wagenknecht, LE; Wofford, MR, 2006)
"Hyperuricemia is associated with the activation of the Nod-like receptor protein 3 inflammasome."3.30C-reactive Protein Levels and Cardiovascular Outcomes After Febuxostat Treatment in Patients with Asymptomatic Hyperuricemia: Post-hoc Analysis of a Randomized Controlled Study. ( Hayashi, T; Hiramitsu, S; Hisatome, I; Jinnouchi, H; Kakuda, H; Kawai, N; Kimura, K; Kojima, S; Matsui, K; Mori, H; Ogawa, H; Ohya, Y; Saito, Y; Sugawara, M; Tokutake, E; Tsujita, K; Uchiyama, K; Wakasa, Y; Waki, M; Yokota, N, 2023)
"Although hyperuricemia is undoubtedly related to CKD, controversial findings have been hitherto reported in patients treated with urate-lowering therapies."2.82Chronic kidney disease: Which role for xanthine oxidoreductase activity and products? ( Battelli, MG; Bolognesi, A; Bortolotti, M; Polito, L, 2022)
"Atherosclerosis is regarded as the disease of the arterial vasculature."2.72Harnessing hyperuricemia to atherosclerosis and understanding its mechanistic dependence. ( Jayachandran, M; Qu, S, 2021)
" In the process of purine metabolism, reactive oxygen species, including superoxide, are generated concomitantly with uric acid production, which may deteriorate endothelial function through the reaction of superoxide with nitric oxide (NO), leading to decreased NO bioavailability and increased production of peroxynitrite, a reactive oxidant."2.58Hyperuricemia and endothelial function: From molecular background to clinical perspectives. ( Higashi, Y; Hisatome, I; Kihara, Y; Maruhashi, T, 2018)
"Hypertension is an established risk factor of cardiovascular morbidity and mortality."2.52[The First Step Aiming at the Prevention of Hypertension and Atherosclerosis. Identification of Individuals at High Risk of Hypertension]. ( Dohi, Y, 2015)
"Uric acid has been formerly considered a major antioxidant in human plasma with possible beneficial anti-atherosclerotic effects."2.48Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications. ( Cravero, E; Muscari, A; Puddu, GM; Puddu, P; Vizioli, L, 2012)
"Acute rupture or erosion of unstable atherosclerotic plaques is a major cause of adverse consequences of atherosclerotic cardiovascular disease, often leading to myocardial infarction or stroke."1.91High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy. ( Chen, B; Cheng, J; He, F; Koyama, H; Liu, W; Lv, J; Wang, Q; Xu, C; Yamamoto, T; Yu, W; Zhao, H, 2023)
"In conclusion, Hyperuricemia is prevalent among Chinese adults."1.72Association of Hyperuricemia with 10-Year Atherosclerotic Cardiovascular Disease Risk among Chinese Adults and Elders. ( Chen, F; Han, S; Liu, J; Xu, T; Yuan, L, 2022)
"Uric acid is an effective antioxidant."1.62Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway. ( Bi, H; Hao, Z; Lin, Y; Liu, Y; Xia, Y; Xie, Y; Yang, X, 2021)
"Hyperuricemia was often found in subjects with an elevated risk of cardiovascular disease (CVD)."1.56Clinical relevance of serum uric acid and abdominal aortic-calcification in a national survey. ( Chen, WL; Li, YW, 2020)
"Insulin resistance was assessed by the homeostatic model assessment (HOMA) index."1.56Uric Acid and Vascular Damage in Essential Hypertension: Role of Insulin Resistance. ( Andreozzi, F; Armentaro, G; Cassano, V; Crescibene, D; Hribal, ML; Magurno, M; Maio, R; Miceli, S; Pelaia, C; Perticone, F; Perticone, M; Sciacqua, A; Sesti, G; Toscani, A, 2020)
"We enrolled 37 ADPKD patients (20 males with 51."1.51Uroflowmetry alterations in patients with autosomal dominant polycystic kidney disease. ( Cianci, R; Ciccariello, M; Lai, S; Mastroluca, D; Mazzaferro, S; Mittherhofer, AP; Ricciuti, GP; Riviello, L; Salciccia, S; Vocaturi, M; Von Heland, M, 2019)
"The cumulative incidence of vascular stenosis was significantly higher in subjects with hyperuricaemia than in those without hyperuricaemia (54."1.51Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis. ( Chen, J; Cheng, W; Cui, Q; Geng, B; Li, N; Song, M; Wang, K; Wang, Y; Yang, J; Yao, Y; Zhou, Y, 2019)
"Experimental diabetes mellitus was produced by a single intraperitoneal injection of STZ (55mg/kg b."1.43Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats. ( Berredjem, H; Berredjem, M; Bouzerna, N; Cheloufi, H; Réggami, Y, 2016)
"Epilepsy is a chronic disease that affects metabolism either alone or through the antiepileptic drug (AED) treatment."1.42Epilepsy and antiepileptic drugs: risk factors for atherosclerosis. ( Abdelaziz, GH; Ahmed, SM; El-Jaafary, SI; Kamel, T; Rabah, AM; Talaat, FM, 2015)
"Hyperuricemia is an important risk factor for atherosclerosis, yet the potential mechanisms are not well understood."1.42Uric acid promotes chemokine and adhesion molecule production in vascular endothelium via nuclear factor-kappa B signaling. ( Feng, XR; Liang, WY; Liu, ML; Wang, YC; Zhang, JW; Zhu, XY, 2015)
"Atherosclerosis is considered as an inflammatory disease, and carotid artery intima-media thickness (IMT) and carotid plaque are generally used as intermediated phenotype of atherosclerosis."1.42Association of interleukin-10 promoter region polymorphisms with risk factors of Atherosclerosis. ( Cho, HC; Chung, IS; Chung, JH; Jun, SE; Park, KO; Shin, DH; Yu, GI, 2015)
"Hyperuricemia is an independent predictor for early atherosclerosis in hypertensive subjects with normal renal function."1.38Uric acid is an important predictor for hypertensive early atherosclerosis. ( Bahadir, E; Citil, R; Deger, SM; Durmaz, AO; Mutluay, R; Sindel, S, 2012)
"Atherosclerotic plaque formation and vascular calcinosis were modeled in a subchronic experiment."1.38Biochemical indicators of atherogenic and protective activity of xydiphone in experimental animals. ( Dreval, AA; Ilyushina, IA; Murashov, AN; Pimenov, MS; Sukhorukov, VS; Yur'eva, EA, 2012)
"Hyperuricaemia was associated with cardiac hypertrophy with an odds ratio (OR) of 1."1.36Role of uric acid in the link between arterial stiffness and cardiac hypertrophy: a cross-sectional study. ( Chen, CC; Chen, HW; Hung, KC; Hwang, JS; Ko, YS; Kuo, CF; Lin, CM; Lin, YS; Luo, SF; See, LC; Shen, YM; Tseng, WY; Wen, MS; Yu, KH, 2010)
"Hyperuricemia is postulated to be a risk factor for atherosclerotic diseases, although whether it is independent of classical atherogenic risk factors is controversial."1.34Higher serum uric acid is associated with increased arterial stiffness in Japanese individuals. ( Hashimoto, H; Ishizaka, N; Ishizaka, Y; Nagai, R; Toda, E; Yamakado, M, 2007)

Research

Studies (142)

TimeframeStudies, this research(%)All Research%
pre-19904 (2.82)18.7374
1990's0 (0.00)18.2507
2000's24 (16.90)29.6817
2010's85 (59.86)24.3611
2020's29 (20.42)2.80

Authors

AuthorsStudies
Yang, Y1
Qu, Y1
Lv, X1
Zhao, R1
Yu, J1
Hu, S1
Kang, J1
Zhang, Y1
Gong, Y1
Cui, T1
Zhang, X1
Yan, Y2
Teng, MS1
Wu, S1
Hsu, LA1
Chou, HH1
Ko, YL1
Lin, Y1
Xie, Y1
Hao, Z1
Bi, H1
Liu, Y1
Yang, X1
Xia, Y1
Kimura, Y2
Tsukui, D2
Kono, H2
Nishizawa, H1
Maeda, N1
Shimomura, I1
Sugiura, T1
Dohi, Y2
Takagi, Y1
Yokochi, T1
Yoshikane, N1
Suzuki, K1
Tomiishi, T1
Nagami, T1
Iwase, M1
Takase, H1
Ohte, N1
Seo, Y1
Shiina, K1
Tomiyama, H2
Tanaka, A2
Yoshida, H1
Eguchi, K2
Kario, K1
Kato, T1
Teragawa, H2
Toyoda, S1
Ohishi, M2
Fukumoto, Y1
Takase, B1
Ishizu, T2
Node, K2
Ma, M1
Wang, L2
Zhong, X1
Zhong, L1
Chen, R1
Li, L1
Mao, M1
Hu, X1
Liu, J2
Li, W1
Wang, C2
Li, G1
Zhou, Y3
Dong, H1
Yu, W4
Liu, W4
Wang, Q4
Xu, C4
Zhao, H4
Lv, J4
He, F4
Chen, B4
Yamamoto, T4
Koyama, H4
Cheng, J4
Baessler, A1
Fischer, M1
Kojima, S1
Uchiyama, K1
Yokota, N1
Tokutake, E1
Wakasa, Y1
Hiramitsu, S1
Waki, M1
Jinnouchi, H1
Kakuda, H1
Hayashi, T1
Kawai, N1
Sugawara, M1
Mori, H1
Tsujita, K1
Matsui, K1
Hisatome, I2
Ohya, Y1
Kimura, K1
Saito, Y1
Ogawa, H1
Chen, F1
Yuan, L1
Xu, T1
Han, S1
Polito, L2
Bortolotti, M1
Battelli, MG2
Bolognesi, A2
Mello, FM3
Bensenor, IM3
Santos, IS3
Bittencourt, MS3
Lotufo, PA4
Fuller, R3
Şaylık, F1
Çınar, T1
Selçuk, M1
Tanboğa, İH1
Kakimoto, M1
Fujii, M1
Sato, I1
Honma, K1
Nakayama, H1
Kirihara, S1
Fukuoka, T1
Ran, S1
Hirohata, S1
Kitamori, K1
Yamamoto, S1
Watanabe, S1
He, B1
Nie, Q1
Wang, F1
Wang, X1
Guo, J1
Fan, X1
Ye, Z1
Liu, P2
Wen, J1
Mazidi, M2
Katsiki, N2
Mikhailidis, DP2
Bartłomiejczyk, MA1
Banach, M2
Yuan, Y1
Hu, JW1
Wang, Y3
Wang, KK1
Zheng, WL1
Chu, C1
Ma, Q1
Liao, YY1
Mu, JJ1
Yanagida, T1
Onda, A1
Hosoyamada, M1
Luo, F1
Zhuo, C1
Alam, AB1
Wu, A1
Power, MC1
West, NA1
Alonso, A2
Li, YW1
Chen, WL1
Cassano, V1
Crescibene, D1
Hribal, ML1
Pelaia, C1
Armentaro, G1
Magurno, M1
Toscani, A1
Miceli, S1
Andreozzi, F1
Maio, R1
Perticone, M1
Sesti, G1
Perticone, F1
Sciacqua, A1
Jayachandran, M1
Qu, S1
Tanaka, K1
Kabayama, M1
Sugimoto, K1
Akasaka, H1
Takami, Y1
Takeya, Y1
Yamamoto, K1
Sekiguchi, T1
Kiyoshige, E1
Akagi, Y1
Godai, K1
Yasumoto, S1
Masui, Y1
Gondo, Y1
Ikebe, K1
Arai, Y1
Ishizaki, T1
Rakugi, H1
Kamide, K1
Metin, N1
Turan, Ç1
Nansseu, JR2
Ama Moor, VJ1
Takam, RDM1
Zing-Awona, B2
Azabji-Kenfack, M1
Tankeu, F1
Tchoula, CM1
Moukette, BM1
Ngogang, JY1
Hannawi, S1
AlSalmi, I1
Moller, I1
Naredo, E1
Zhao, J2
Chen, H2
Liu, N1
Chen, J3
Gu, Y1
Yang, K1
Shen, S1
Qi, H1
He, X1
Lu, Y1
Yang, C1
Li, F1
Qiang, D1
Shui, K1
Zhou, L1
Weng, X1
Shen, Z1
Wu, L1
De Pergola, G1
Cortese, F1
Termine, G1
Meliota, G1
Carbonara, R1
Masiello, M1
Cortese, AM1
Silvestris, F1
Caccavo, D1
Ciccone, MM1
Devarajan, A1
Santana, MS1
Nascimento, KP1
Benseãor, IM1
Meotti, FC1
Buzas, R1
Tautu, OF1
Dorobantu, M1
Ivan, V1
Lighezan, D1
Marković Boras, M1
Čaušević, A1
Brizić, I1
Mikulić, I1
Vasilj, M1
Jelić Knezović, N1
Acar, T1
Güzey Aras, Y1
Gül, SS1
Acar, AB1
Cho, YS1
Bae, JH1
Moon, SH1
Hyun, SH1
Choi, JY1
Kim, BT1
Lee, KH1
Maruhashi, T1
Kihara, Y1
Higashi, Y2
Biyik, Z1
Guney, I1
Bombelli, M1
Macchiarulo, M1
Facchetti, R1
Maggiolini, D1
Cuspidi, C1
Parati, G1
Mancia, G1
Grassi, G1
Antonini-Canterin, F1
Di Nora, C1
Pellegrinet, M1
Vriz, O1
La Carrubba, S1
Carerj, S1
Zito, C1
Matescu, A1
Ravasel, A1
Cosei, I1
Popescu, BA1
Lai, S1
Mittherhofer, AP1
Cianci, R1
Riviello, L1
Vocaturi, M1
Mastroluca, D1
Ciccariello, M1
Von Heland, M1
Ricciuti, GP1
Salciccia, S1
Mazzaferro, S1
Concistrè, A1
Petramala, L1
Bisogni, V1
Mezzadri, M1
Olmati, F1
Saracino, V1
Oliviero, G1
Bonvicini, M1
Tonnarini, G1
Iannucci, G1
Letizia, C1
Song, M1
Li, N2
Yao, Y1
Wang, K1
Yang, J2
Cui, Q1
Geng, B1
Cheng, W1
Wang, A1
Barber, JR1
Tin, A1
De Marzo, AM1
Kottgen, A3
Joshu, CE1
Platz, EA1
Kupusinac, A1
Doroslovački, R1
Malbaški, D1
Srdić, B1
Stokić, E1
Wang, H2
Jacobs, DR1
Gaffo, AL1
Gross, MD1
Goff, DC1
Carr, JJ1
Cicero, AF1
Salvi, P1
D'Addato, S1
Rosticci, M1
Borghi, C1
Bao, YS1
Jia, XB1
Ji, Y1
Zhao, SL1
Na, SP1
Knowles, JW1
Reaven, G1
Bonakdaran, S1
Kharaqani, B1
Zhang, J1
Xiang, G1
Xiang, L1
Sun, H1
Sarmento, PL1
Plavnik, FL1
Scaciota, A1
Lima, JO1
Miranda, RB1
Ajzen, SA1
Roszkowska, R1
Taranta-Janusz, K1
Tenderenda-Banasiuk, E1
Wasilewska, A1
Wijnands, JM1
Boonen, A1
Dagnelie, PC1
van Greevenbroek, MM1
van der Kallen, CJ1
Ferreira, I1
Schalkwijk, CG1
Feskens, EJ1
Stehouwer, CD1
van der Linden, S1
Arts, IC1
Talaat, FM1
Kamel, T1
Rabah, AM1
Ahmed, SM1
El-Jaafary, SI1
Abdelaziz, GH1
Badeĭnikova, KK1
Mazaev, AP1
Toguzova, ZA1
Mamedov, MN1
Didigova, RT1
Solomenchuk, TN1
Semegen-Bodak, KV1
Slaba, NA1
Chngrian, GV1
Mysyshin, MB1
Rasheed, H1
Hughes, K1
Flynn, TJ1
Merriman, TR1
Kosacka, M1
Brzecka, A1
Piesiak, P1
Korzeniewska, A1
Jankowska, R1
Liang, WY1
Zhu, XY1
Zhang, JW1
Feng, XR1
Wang, YC1
Liu, ML1
Li, LX1
Dong, XH1
Li, MF1
Zhang, R1
Li, TT1
Shen, J2
Bao, YQ1
Jia, WP1
Yu, GI1
Jun, SE1
Cho, HC1
Park, KO1
Chung, JH1
Shin, DH1
Chung, IS1
Mayer, FJ1
Mannhalter, C1
Minar, E1
Schillinger, M1
Chavakis, T1
Siegert, G1
Arneth, BM1
Koppensteiner, R1
Hoke, M1
Mykhaĭlenko, OIu1
Chen, Y4
Xu, B1
Sun, W1
Sun, J1
Wang, T1
Xu, Y1
Xu, M2
Lu, J1
Li, X1
Bi, Y1
Wang, W2
Ning, G1
Wolak, T1
Shoham-Vardi, I1
Sergienko, R1
Sheiner, E1
Bortolasci, CC1
Vargas, HO1
Vargas Nunes, SO1
de Melo, LG1
de Castro, MR1
Moreira, EG1
Dodd, S1
Barbosa, DS1
Berk, M1
Maes, M2
Altun, B1
Cintosun, U1
Ozturk, K1
Zhang, F1
Wang, D1
Kummer, AE1
Grams, M2
Lutsey, P1
Matsushita, K1
Folsom, AR2
Coresh, J3
Castejon, R1
Jimenez-Ortiz, C1
Rosado, S1
Tutor-Ureta, P1
Mellor-Pita, S1
Yebra-Bango, M1
Zheng, H1
Ding, Y1
Miao, P1
Burke, BT1
Law, A1
Baer, AN1
McAdams-DeMarco, MA1
Moor, VJ1
Nouaga, ME1
Tchanana, G1
Ketcha, A1
Réggami, Y1
Berredjem, H1
Cheloufi, H1
Berredjem, M1
Bouzerna, N1
Parrinello, CM1
Grams, ME1
Sang, Y1
Couper, D1
Wruck, LM1
Li, D1
Eckfeldt, JH1
Selvin, E1
Oyama, J1
Sato, Y1
Sata, M1
Taguchi, I1
Kuroyanagi, T1
Ishizaka, N2
Kanzaki, Y1
Yamada, H1
Maemura, K1
Ako, J1
Bando, YK1
Ueda, S1
Inoue, T1
Murohara, T1
Kubota, Y1
McAdams-DeMarco, M1
Kırça, M1
Oğuz, N1
Çetin, A1
Uzuner, F1
Yeşilkaya, A1
Altay, M1
Karakoç, MA1
Çakır, N1
Yılmaz Demirtaş, C1
Cerit, ET1
Aktürk, M1
Ateş, İ1
Bukan, N1
Arslan, M1
Chang, Y1
Li, Y2
Guo, X1
Guo, L1
Sun, Y1
Okazaki, H1
Shirakabe, A1
Kobayashi, N1
Hata, N1
Shinada, T1
Matsushita, M1
Yamamoto, Y1
Shibata, Y1
Shibuya, J1
Shiomura, R1
Nishigoori, S1
Asai, K1
Shimizu, W1
Kushiyama, A1
Nakatsu, Y1
Matsunaga, Y1
Yamamotoya, T1
Mori, K1
Ueda, K1
Inoue, Y1
Sakoda, H1
Fujishiro, M1
Ono, H1
Asano, T1
Oliveira, SR1
Kallaur, AP1
Lopes, J1
Colado Simão, AN1
Reiche, EM1
de Almeida, ERD1
Morimoto, HK1
de Carvalho Jennings de Pereira, WL1
Alfieri, DF1
Flauzino, T1
de Meleck Proença, C1
Gomes, AM1
Kaimen-Maciel, DR1
Qin, G1
Chen, Z1
Su, W1
Geng, X1
Chen, X1
Xu, X1
Pan, W1
Auclair, S1
Silberberg, M1
Gueux, E1
Morand, C1
Mazur, A1
Milenkovic, D1
Scalbert, A1
Vekic, J1
Jelic-Ivanovic, Z1
Spasojevic-Kalimanovska, V1
Memon, L1
Zeljkovic, A1
Bogavac-Stanojevic, N1
Spasic, S1
Gonzalez-Gay, MA2
Gonzalez-Juanatey, C2
Vazquez-Rodriguez, TR2
Gomez-Acebo, I1
Miranda-Filloy, JA1
Paz-Carreira, J1
Martin, J1
Llorca, J2
Percario, S1
Odorizzi, VF1
Souza, DR1
Pinhel, MA1
Gennari, JL1
Gennari, MS1
Godoy, MF1
Mosley, TH1
Huang, X1
Dierssen, T1
Brandstätter, A1
Lamina, C1
Kiechl, S1
Hunt, SC1
Coassin, S1
Paulweber, B1
Kramer, F1
Summerer, M1
Willeit, J1
Kedenko, L1
Adams, TD1
Kronenberg, F1
Sabio, JM1
Vargas-Hitos, JA1
Mediavilla, JD1
Navarrete-Navarrete, N1
Zamora-Posadas, M1
Pérez-Vicente, S1
Hidalgo-Tenorio, C1
Díaz-Chamorro, A1
Jáimez, L1
Jiménez-Alonso, J1
Krishnan, E1
Kuo, CF1
Yu, KH1
Luo, SF1
Ko, YS1
Wen, MS1
Lin, YS1
Hung, KC1
Chen, CC1
Lin, CM1
Hwang, JS1
Tseng, WY1
Chen, HW1
Shen, YM1
See, LC1
Kiseljaković, E1
Valjevac, A1
Hasić, S1
Nakas-Ićindić, E1
Dzubur, A1
Jadrić, R1
Gilardini, L1
Pasqualinotto, L1
Di Matteo, S1
Caffetto, K1
Croci, M1
Girola, A1
Invitti, C1
Saeed, A1
Herlitz, H1
Nowakowska-Fortuna, E1
Nilsson, U1
Alhadad, A1
Jensen, G1
Mattiasson, I1
Lindblad, B1
Gottsäter, A1
Guron, G1
McIntyre, NJ1
Fluck, RJ1
McIntyre, CW1
Taal, MW1
Zhang, Z1
Bian, L1
Choi, Y1
Resl, M1
Clodi, M1
Neuhold, S1
Kromoser, H1
Riedl, M1
Vila, G1
Prager, R1
Pacher, R1
Strunk, G1
Luger, A1
Hülsmann, M1
Chuang, YC1
Chuang, HY1
Lin, TK1
Chang, CC1
Lu, CH1
Chang, WN1
Chen, SD1
Tan, TY1
Huang, CR1
Chan, SH1
Mutluay, R1
Deger, SM1
Bahadir, E1
Durmaz, AO1
Citil, R1
Sindel, S1
Puddu, P1
Puddu, GM1
Cravero, E1
Vizioli, L1
Muscari, A1
Caliskan, Y1
Ozkok, A1
Akagun, T1
Alpay, N1
Guz, G1
Polat, N1
Tufan, F1
Ecder, T1
Bozfakioglu, S1
D'Marco, L1
García, I1
Vega, C1
Kushnarenko, NN1
Govorin, AV1
Shcherbakova, OA1
Sotnikova, SG1
Ivanitskaia, OV1
Oikonen, M1
Wendelin-Saarenhovi, M1
Lyytikäinen, LP1
Siitonen, N1
Loo, BM1
Jula, A1
Seppälä, I1
Saarikoski, L1
Lehtimäki, T1
Hutri-Kähönen, N1
Juonala, M1
Kähönen, M1
Huupponen, R1
Viikari, JS1
Raitakari, OT1
Yur'eva, EA1
Sukhorukov, VS1
Murashov, AN1
Pimenov, MS1
Ilyushina, IA1
Dreval, AA1
Baliarsingh, S1
Sharma, N1
Mukherjee, R1
Gür, M1
Sahin, DY1
Elbasan, Z1
Kalkan, GY1
Yıldız, A1
Kaya, Z1
Özaltun, B1
Çaylı, M1
Liang, J1
Zhou, N1
Teng, F1
Zou, C1
Qi, L1
PUIG-MUSET, P1
LAPORTE, J1
VALDECASAS, FG1
HANSEN, OE1
BARNETT, AJ1
CARSON, V1
DE MEIRING, PV1
BEAUMONT, JL1
SCHWARTZ, D1
Saijo, Y1
Utsugi, M1
Yoshioka, E1
Horikawa, N1
Sato, T1
Gong, YY1
Kishi, R1
Erdogan, D1
Gullu, H1
Caliskan, M1
Yildirim, E1
Bilgi, M1
Ulus, T1
Sezgin, N1
Muderrisoglu, H2
Demirbag, R1
Yilmaz, R1
Ulucay, A1
Unlu, D1
Ruggiero, C2
Cherubini, A2
Ble, A1
Bos, AJ1
Maggio, M2
Dixit, VD1
Lauretani, F2
Bandinelli, S2
Senin, U2
Ferrucci, L2
Ishizaka, Y1
Toda, E1
Hashimoto, H1
Nagai, R1
Yamakado, M1
Ariel, RJ1
Mellen, PB1
Bleyer, AJ1
Erlinger, TP1
Evans, GW1
Nieto, FJ1
Wagenknecht, LE1
Wofford, MR1
Herrington, DM1
Wei, YD1
Hu, DY1
Zhang, RF1
Zheng, LQ1
Li, J1
Yu, JM1
Xing, Y1
Bianchi, C1
Penno, G1
Malloggi, L1
Barontini, R1
Corfini, M1
Giovannitti, MG1
Di Cianni, G1
Del Prato, S1
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Tseng, CH1
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Yildirir, A1
Atar, I1
Pirat, B1
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Ozin, B1
Wakabayashi, I1
Masuda, H1
Fukui, M1
Tanaka, M1
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Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Randomized, Comparative Trial on the Effect of Febuxostat in Preventing Cerebral and Cardiorenovascular Events in Patients With Hyperuricemia[NCT01984749]1,000 participants (Anticipated)Interventional2013-11-30Active, not recruiting
Effect of the Interaction Between Environmental Factors and Genetic Predisposition on Long-term Blood Pressure in Chinese Population[NCT02734472]5,298 participants (Anticipated)Observational2016-07-31Recruiting
Effects of Allopurinol on Inflammatory Markers and Morphostructural Changes Evidenced by Musculoskeletal Ultrasound in Individuals With Asymptomatic Hyperuricemia. A Proof of Concept[NCT04012294]Phase 3200 participants (Anticipated)Interventional2019-08-30Recruiting
The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy[NCT05414669]Phase 435 participants (Actual)Interventional2020-08-06Completed
Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study[NCT03700645]Phase 4100 participants (Anticipated)Interventional2018-12-01Not yet recruiting
[NCT02797028]Phase 4320 participants (Anticipated)Interventional2015-01-31Recruiting
Assessing the Role of the NLRP3 Inflammasome in Driving Inflammation in Affected Joints of Patients With Intercritical Gout[NCT04125459]8 participants (Anticipated)Observational2020-01-22Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

18 reviews available for uric acid and Atherosclerosis

ArticleYear
Uric Acid in Inflammation and the Pathogenesis of Atherosclerosis.
    International journal of molecular sciences, 2021, Nov-17, Volume: 22, Issue:22

    Topics: Animals; Atherosclerosis; Comorbidity; Diabetes Mellitus, Type 2; Gout; Humans; Hypertension; Hyperu

2021
Impact of hyperuricemia on chronic kidney disease and atherosclerotic cardiovascular disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:4

    Topics: Atherosclerosis; Cardiovascular Diseases; Female; Humans; Hyperuricemia; Male; Renal Insufficiency,

2022
[Novel options to maximize oral lipid lowering treatment : Role of bempedoic acid in combination treatment].
    Herz, 2022, Volume: 47, Issue:3

    Topics: Anticholesteremic Agents; Atherosclerosis; Cholesterol, LDL; Cross-Sectional Studies; Dicarboxylic A

2022
Chronic kidney disease: Which role for xanthine oxidoreductase activity and products?
    Pharmacological research, 2022, Volume: 184

    Topics: Atherosclerosis; Diabetes Mellitus, Type 2; Humans; Hypertension; Hyperuricemia; Purines; Reactive O

2022
Serum Uric Acid Levels and Subclinical Atherosclerosis: Results From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
    Current problems in cardiology, 2023, Volume: 48, Issue:3

    Topics: Adult; Atherosclerosis; Brazil; Carotid Intima-Media Thickness; Female; Humans; Longitudinal Studies

2023
Serum Uric Acid Levels and Subclinical Atherosclerosis: Results From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
    Current problems in cardiology, 2023, Volume: 48, Issue:3

    Topics: Adult; Atherosclerosis; Brazil; Carotid Intima-Media Thickness; Female; Humans; Longitudinal Studies

2023
Serum Uric Acid Levels and Subclinical Atherosclerosis: Results From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
    Current problems in cardiology, 2023, Volume: 48, Issue:3

    Topics: Adult; Atherosclerosis; Brazil; Carotid Intima-Media Thickness; Female; Humans; Longitudinal Studies

2023
Serum Uric Acid Levels and Subclinical Atherosclerosis: Results From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
    Current problems in cardiology, 2023, Volume: 48, Issue:3

    Topics: Adult; Atherosclerosis; Brazil; Carotid Intima-Media Thickness; Female; Humans; Longitudinal Studies

2023
Harnessing hyperuricemia to atherosclerosis and understanding its mechanistic dependence.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Atherosclerosis; Endothelial Cells; Humans; Hyperuricemia; Uric Acid; Xanthine Oxidase

2021
Role of Hyperhomocysteinemia and Hyperuricemia in Pathogenesis of Atherosclerosis.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:12

    Topics: Animals; Atherosclerosis; Biomarkers; Cell Proliferation; Endoplasmic Reticulum Stress; Endothelium,

2017
Cross-talk between renal lithogenesis and atherosclerosis: an unveiled link between kidney stone formation and cardiovascular diseases.
    Clinical science (London, England : 1979), 2018, 03-30, Volume: 132, Issue:6

    Topics: Animals; Arteries; Atherosclerosis; Calcium; Crystallization; Humans; Kidney; Kidney Calculi; Lipids

2018
Hyperuricemia and endothelial function: From molecular background to clinical perspectives.
    Atherosclerosis, 2018, Volume: 278

    Topics: Antioxidants; Atherosclerosis; Cardiovascular Diseases; Catalysis; Endothelium, Vascular; Humans; Hy

2018
Association of serum uric acid and metabolic syndrome in type 2 diabetes.
    Current diabetes reviews, 2014, Volume: 10, Issue:2

    Topics: Adult; Atherosclerosis; Biomarkers; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Cross-Section

2014
Xanthine oxidoreductase in atherosclerosis pathogenesis: not only oxidative stress.
    Atherosclerosis, 2014, Volume: 237, Issue:2

    Topics: Adipocytes; Animals; Atherosclerosis; Cardiovascular Diseases; Cell Differentiation; Cell Movement;

2014
[The First Step Aiming at the Prevention of Hypertension and Atherosclerosis. Identification of Individuals at High Risk of Hypertension].
    Rinsho byori. The Japanese journal of clinical pathology, 2015, Volume: 63, Issue:11

    Topics: Albuminuria; Ankle Brachial Index; Atherosclerosis; Biomarkers; Blood Pressure; Cardiovascular Disea

2015
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Atherosclerosis; Disease Progression; Free Radicals; Heart Failure; Humans; Inflammasomes;

2016
Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout.
    Rheumatology (Oxford, England), 2010, Volume: 49, Issue:7

    Topics: Atherosclerosis; Gout; Humans; Hyperuricemia; Inflammasomes; Lipid Metabolism; Lipids; Oxidative Str

2010
Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications.
    Journal of cardiology, 2012, Volume: 59, Issue:3

    Topics: Allopurinol; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Humans;

2012
Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications.
    Journal of cardiology, 2012, Volume: 59, Issue:3

    Topics: Allopurinol; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Humans;

2012
Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications.
    Journal of cardiology, 2012, Volume: 59, Issue:3

    Topics: Allopurinol; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Humans;

2012
Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications.
    Journal of cardiology, 2012, Volume: 59, Issue:3

    Topics: Allopurinol; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Humans;

2012
[HYPERURICEMIA AND ATHEROSCLEROSIS].
    Ugeskrift for laeger, 1964, Jun-25, Volume: 126

    Topics: Arteriosclerosis; Atherosclerosis; Blood; Cerebrovascular Disorders; Coronary Disease; Gout; Humans;

1964
[The current opinion on inflammatory, biochemistry and hemostatic markers and factors in atherosclerosis. Part II].
    Przeglad lekarski, 2006, Volume: 63, Issue:9

    Topics: Animals; Atherosclerosis; Biomarkers; Causality; Clinical Trials as Topic; Comorbidity; Fibrin Fibri

2006
Uric acid and oxidative stress: relative impact on cardiovascular risk?
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2007, Volume: 17, Issue:6

    Topics: Atherosclerosis; Biomarkers; Cardiovascular Diseases; Humans; Hyperuricemia; Oxidative Stress; React

2007

Trials

7 trials available for uric acid and Atherosclerosis

ArticleYear
Differential effect of a xanthine oxidase inhibitor on arterial stiffness and carotid atherosclerosis: a subanalysis of the PRIZE study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:4

    Topics: Ankle Brachial Index; Atherosclerosis; Awards and Prizes; Carotid Artery Diseases; Enzyme Inhibitors

2022
C-reactive Protein Levels and Cardiovascular Outcomes After Febuxostat Treatment in Patients with Asymptomatic Hyperuricemia: Post-hoc Analysis of a Randomized Controlled Study.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:5

    Topics: Atherosclerosis; C-Reactive Protein; Febuxostat; Female; Humans; Hyperuricemia; Inflammation; Male;

2023
Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis.
    Journal of hypertension, 2019, Volume: 37, Issue:4

    Topics: Antihypertensive Agents; Atenolol; Atherosclerosis; Blood Pressure; Carotid Artery Diseases; Dihydro

2019
The Effects of Allopurinol on the Carotid Intima-media Thickness in Patients with Type 2 Diabetes and Asymptomatic Hyperuricemia: A Three-year Randomized Parallel-controlled Study.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:17

    Topics: Adult; Aged; Allopurinol; Asian People; Atherosclerosis; Biomarkers; Blood Pressure; C-Reactive Prot

2015
Rationale and design of a multicenter randomized study for evaluating vascular function under uric acid control using the xanthine oxidase inhibitor, febuxostat: the PRIZE study.
    Cardiovascular diabetology, 2016, Jun-18, Volume: 15

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Carotid Artery, Common; Dose-Response Relationship,

2016
Sex difference in the distribution of atherosclerotic risk factors and their association with peripheral arterial disease in Taiwanese type 2 diabetic patients.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Atherosclerosis; Blood Pressure; Body Mass Index; Cohor

2007
Usefulness of uric acid to predict changes in C-reactive protein and interleukin-6 in 3-year period in Italians aged 21 to 98 years.
    The American journal of cardiology, 2007, Jul-01, Volume: 100, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Cohort

2007

Other Studies

117 other studies available for uric acid and Atherosclerosis

ArticleYear
Sesamol supplementation alleviates nonalcoholic steatohepatitis and atherosclerosis in high-fat, high carbohydrate and high-cholesterol diet-fed rats.
    Food & function, 2021, Oct-04, Volume: 12, Issue:19

    Topics: Animals; Aorta; Atherosclerosis; Benzodioxoles; Cholesterol, Dietary; Diet, High-Fat; Dietary Carboh

2021
Pleiotropic Effects of Functional
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: Adult; Atherosclerosis; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Body Mass Index; DNA Met

2021
Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway.
    Journal of immunology research, 2021, Volume: 2021

    Topics: Antioxidants; Atherosclerosis; Carboxylic Ester Hydrolases; Cell Adhesion; Cell Line, Tumor; Cells,

2021
Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females.
    Journal of atherosclerosis and thrombosis, 2022, Nov-01, Volume: 29, Issue:11

    Topics: Atherosclerosis; Carotid Arteries; Carotid Intima-Media Thickness; Female; Humans; Male; Middle Aged

2022
Age and Gender Differences Between Carotid Intima-Media Thickness and Serum Uric Acid.
    The American journal of cardiology, 2022, 06-01, Volume: 172

    Topics: Adult; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; F

2022
Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2022, Volume: 32, Issue:7

    Topics: Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Carotid Stenosis; Choleste

2022
High Level of Uric Acid Promotes Atherosclerosis by Targeting NRF2-Mediated Autophagy Dysfunction and Ferroptosis.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Atherosclerosis; Autophagy; Ferroptosis; Hyperuricemia; Mice; NF-E2-Related Factor 2; Plaqu

2022
Association of Hyperuricemia with 10-Year Atherosclerotic Cardiovascular Disease Risk among Chinese Adults and Elders.
    International journal of environmental research and public health, 2022, 05-31, Volume: 19, Issue:11

    Topics: Adult; Aged; Atherosclerosis; Cardiovascular Diseases; China; Cross-Sectional Studies; Female; Human

2022
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
    Journal of atherosclerosis and thrombosis, 2023, Sep-01, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric

2023
The Relationship between Uric Acid/Albumin Ratio and Carotid Intima-Media Thickness in Patients with Hypertension.
    Arquivos brasileiros de cardiologia, 2023, Volume: 120, Issue:5

    Topics: Atherosclerosis; C-Reactive Protein; Carotid Intima-Media Thickness; Humans; Hypertension; Inflammat

2023
Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats.
    Journal of applied biomedicine, 2023, Volume: 21, Issue:2

    Topics: Animals; Antioxidants; Atherosclerosis; Diet, High-Fat; Enzyme Inhibitors; Febuxostat; Lipids; Non-a

2023
Hyperuricemia promotes the progression of atherosclerosis by activating endothelial cell pyroptosis via the ROS/NLRP3 pathway.
    Journal of cellular physiology, 2023, Volume: 238, Issue:8

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Human Umbilical Vein Endothelial Cells; Humans; Hyperur

2023
Association of Empirical Dietary Atherogenic Indices with All-Cause and Cause-Specific Mortality in a Multi-Ethnic Adult Population of the United States.
    Nutrients, 2019, Oct-01, Volume: 11, Issue:10

    Topics: Apolipoprotein B-100; Atherosclerosis; Biomarkers; Cause of Death; Diet, Atherogenic; Feeding Behavi

2019
Association between atherogenic index of plasma and subclinical renal damage over a 12-year follow-up: Hanzhong adolescent hypertension study.
    European journal of clinical nutrition, 2020, Volume: 74, Issue:2

    Topics: Adolescent; Atherosclerosis; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Hypertensio

2020
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:3

    Topics: Adult; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Benzbromarone; Biomarkers; Disease M

2020
Association between uric acid and brachial-ankle pulse wave velocity: secondary analysis of data from a cross-sectional study.
    Scientific reports, 2020, 02-10, Volume: 10, Issue:1

    Topics: Adult; Ankle Brachial Index; Atherosclerosis; Biomarkers; Cross-Sectional Studies; Female; Humans; I

2020
Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort.
    Journal of the neurological sciences, 2020, Jul-15, Volume: 414

    Topics: Aged; Atherosclerosis; Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Humans; Middle Aged

2020
Clinical relevance of serum uric acid and abdominal aortic-calcification in a national survey.
    Clinical cardiology, 2020, Volume: 43, Issue:10

    Topics: Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Biomarkers; China; Female; Humans; Hyperuricemia

2020
Uric Acid and Vascular Damage in Essential Hypertension: Role of Insulin Resistance.
    Nutrients, 2020, Aug-19, Volume: 12, Issue:9

    Topics: Adult; Atherosclerosis; Biomarkers; C-Reactive Protein; Essential Hypertension; Female; Humans; Insu

2020
Association between uric acid and atherosclerosis in community-dwelling older people: The SONIC study.
    Geriatrics & gerontology international, 2021, Volume: 21, Issue:1

    Topics: Aged; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cross-Sectional Stud

2021
Increases in uric acid and monocyte-high-density lipoprotein ratio as possible atherosclerotic indicators in acne patients using isotretinoin.
    Journal of cosmetic dermatology, 2021, Volume: 20, Issue:9

    Topics: Acne Vulgaris; Atherosclerosis; Cholesterol, HDL; Humans; Isotretinoin; Lipoproteins, HDL; Monocytes

2021
Cameroonian professional soccer players and risk of atherosclerosis.
    BMC research notes, 2017, Jun-02, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antioxidants; Atherosclerosis; Athletes; Autoantibodies; Cameroon; Cholesterol, L

2017
Uric acid is independent cardiovascular risk factor, as manifested by increased carotid intima-media thickness in rheumatoid arthritis patients.
    Clinical rheumatology, 2017, Volume: 36, Issue:8

    Topics: Adult; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Intima-M

2017
Aerobic Exercise for a Duration of 90 min or Longer Per Week may Reduce the Atherogenic Index of Plasma.
    Scientific reports, 2018, 01-29, Volume: 8, Issue:1

    Topics: Atherosclerosis; Blood Glucose; Blood Pressure; Body Mass Index; China; Cross-Sectional Studies; Exe

2018
Uric Acid, Metabolic Syndrome and Atherosclerosis: The Chicken or the Egg, Which Comes First?
    Endocrine, metabolic & immune disorders drug targets, 2018, Volume: 18, Issue:3

    Topics: Adult; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickness; Female; Humans; Insulin; Leptin;

2018
Allantoin as an independent marker associated with carotid intima-media thickness in subclinical atherosclerosis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Volume: 51, Issue:8

    Topics: Allantoin; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickness; Double-Blind Method; Humans;

2018
Serum uric acid and arterial hypertension-Data from Sephar III survey.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickn

2018
A relation of serum homocysteine, uric acid and C-reactive protein level in patients with acute myocardial infarction.
    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2018, Aug-01, Volume: 15, Issue:2

    Topics: Aged; Atherosclerosis; Biomarkers; C-Reactive Protein; Female; Homocysteine; Humans; Hyperhomocystei

2018
Can high uric acid levels be an independent risk factor for acute ischemic stroke due to large-artery atherosclerosis?
    Ideggyogyaszati szemle, 2018, Jul-30, Volume: 71, Issue:7-08

    Topics: Atherosclerosis; Bilirubin; Biomarkers; Brain Ischemia; Carotid Intima-Media Thickness; Carotid Sten

2018
Serum uric acid in asymptomatic adults is weakly associated with carotid artery FDG uptake but not intima-media thickness.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020, Volume: 27, Issue:5

    Topics: Adult; Asymptomatic Diseases; Atherosclerosis; Carotid Arteries; Carotid Intima-Media Thickness; Cro

2020
Relationship Between Uric Acid, Proteinuria, and Atherogenic Index of Plasma in Renal Transplant Patients.
    Transplantation proceedings, 2018, Volume: 50, Issue:10

    Topics: Adult; Aged; Atherosclerosis; Cardiovascular Diseases; Cohort Studies; Female; Glomerular Filtration

2018
Association of ideal cardiovascular health metrics with serum uric acid, inflammation and atherogenic index of plasma: A population-based survey.
    Atherosclerosis, 2019, Volume: 284

    Topics: Adult; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Female

2019
Effect of uric acid serum levels on carotid arterial stiffness and intima-media thickness: A high resolution Echo-Tracking Study.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2019, Mar-27, Volume: 89, Issue:1

    Topics: Adult; Aged; Atherosclerosis; Carotid Arteries; Carotid Intima-Media Thickness; Female; Humans; Hype

2019
Uroflowmetry alterations in patients with autosomal dominant polycystic kidney disease.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:7

    Topics: Adult; Aged; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Intima-Media Thickness; C

2019
Subclinical atherosclerosis due to increase of plasma aldosterone concentrations in essential hypertensive individuals.
    Journal of hypertension, 2019, Volume: 37, Issue:11

    Topics: Adult; Aldosterone; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carotid Intima-Media Thicknes

2019
Longitudinal association between serum uric acid levels and multiterritorial atherosclerosis.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8

    Topics: Adult; Arteries; Asian People; Atherosclerosis; Cohort Studies; Constriction, Pathologic; Female; Hu

2019
Serum Urate, Genetic Variation, and Prostate Cancer Risk: Atherosclerosis Risk in Communities (ARIC) Study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019, Volume: 28, Issue:7

    Topics: Atherosclerosis; Genetic Variation; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk Factors; Ur

2019
A primary estimation of the cardiometabolic risk by using artificial neural networks.
    Computers in biology and medicine, 2013, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Atherosclerosis; Blood Pressure; Body Mass Index; Female; Fibr

2013
Longitudinal association between serum urate and subclinical atherosclerosis: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
    Journal of internal medicine, 2013, Volume: 274, Issue:6

    Topics: Adolescent; Adult; Age Factors; Atherosclerosis; Biomarkers; Body Mass Index; Coronary Artery Diseas

2013
Association between serum uric acid, hypertension, vascular stiffness and subclinical atherosclerosis: data from the Brisighella Heart Study.
    Journal of hypertension, 2014, Volume: 32, Issue:1

    Topics: Adult; Atherosclerosis; Female; Humans; Hypertension; Italy; Male; Metabolic Syndrome; Middle Aged;

2014
High prevalence and risk factors for kidney dysfunction in patients with atherosclerotic cardio-cerebrovascular disease.
    QJM : monthly journal of the Association of Physicians, 2014, Volume: 107, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Atherosclerosis; Cerebrovascular Disorders; China; Coronary Di

2014
Hyperuricaemia: the unintended consequence of insulin resistance/compensatory hyperinsulinaemia. Philanthropy gone awry.
    Journal of internal medicine, 2014, Volume: 276, Issue:2

    Topics: Atherosclerosis; Coronary Artery Disease; Female; Humans; Male; Uric Acid

2014
Serum uric acid is associated with arterial stiffness in men with newly diagnosed type 2 diabetes mellitus.
    Journal of endocrinological investigation, 2014, Volume: 37, Issue:5

    Topics: Adult; Age Factors; Atherosclerosis; C-Reactive Protein; Carotid Arteries; China; Cross-Sectional St

2014
Relationship between cardiovascular risk factors and the echogenicity and pattern of the carotid intima-media complex in men.
    Sao Paulo medical journal = Revista paulista de medicina, 2014, Volume: 132, Issue:2

    Topics: Adult; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Carotid Artery, Common; Carotid

2014
Increased circulating inflammatory markers may indicate that formula-fed children are at risk of atherosclerosis.
    Acta paediatrica (Oslo, Norway : 1992), 2014, Volume: 103, Issue:8

    Topics: Atherosclerosis; Biomarkers; Breast Feeding; Chemokine CCL2; Child, Preschool; Female; Humans; Infan

2014
The cross-sectional association between uric acid and atherosclerosis and the role of low-grade inflammation: the CODAM study.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:11

    Topics: Adult; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cross-S

2014
Epilepsy and antiepileptic drugs: risk factors for atherosclerosis.
    The International journal of neuroscience, 2015, Volume: 125, Issue:7

    Topics: Adult; Analysis of Variance; Anticonvulsants; Atherosclerosis; C-Reactive Protein; Carotid Intima-Me

2015
[Detection of early markers of atherosclerosis in men with various levels of risk of cardiovascular complications].
    Kardiologiia, 2014, Volume: 54, Issue:6

    Topics: Adult; Ankle Brachial Index; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Arteries;

2014
[Proaterogenic metabolic disorders in patients with chronic kidney disease nondiabetic origin: possibility of statin therapy].
    Kardiologiia, 2014, Volume: 54, Issue:6

    Topics: Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Blood Pressure; Cardiotonic Agents; Disease

2014
Mendelian randomization provides no evidence for a causal role of serum urate in increasing serum triglyceride levels.
    Circulation. Cardiovascular genetics, 2014, Volume: 7, Issue:6

    Topics: Apolipoproteins; Atherosclerosis; Demography; Female; Genetic Association Studies; Humans; Least-Squ

2014
Soluble ligand CD40 and uric acid as markers of atheromatosis in patients with obstructive sleep apnea.
    Advances in experimental medicine and biology, 2015, Volume: 839

    Topics: Adult; Atherosclerosis; Biomarkers; Case-Control Studies; CD40 Ligand; Female; Humans; Hypertension;

2015
Uric acid promotes chemokine and adhesion molecule production in vascular endothelium via nuclear factor-kappa B signaling.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:2

    Topics: Animals; Atherosclerosis; Cell Adhesion; Cell Adhesion Molecules; Cell Survival; Chemokine CCL2; Che

2015
Serum uric acid levels are associated with hypertension and metabolic syndrome but not atherosclerosis in Chinese inpatients with type 2 diabetes.
    Journal of hypertension, 2015, Volume: 33, Issue:3

    Topics: Aged; Asian People; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cross-

2015
Association of interleukin-10 promoter region polymorphisms with risk factors of Atherosclerosis.
    International journal of immunogenetics, 2015, Volume: 42, Issue:1

    Topics: Atherosclerosis; Blood Pressure; Carotid Intima-Media Thickness; Cholesterol; Female; Homocysteine;

2015
The impact of uric acid on long-term mortality in patients with asymptomatic carotid atherosclerotic disease.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:2

    Topics: Aged; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Female; Humans; Male; Middle Aged; Progn

2015
[Atypical risk factors of atherosclerosis in patients with hypothyroidism].
    Likars'ka sprava, 2013, Issue:6

    Topics: Adult; Aged; Atherosclerosis; Biomarkers; Body Mass Index; C-Reactive Protein; Carotid Arteries; Fem

2013
Impact of the Serum Uric Acid Level on Subclinical Atherosclerosis in Middle-aged and Elderly Chinese.
    Journal of atherosclerosis and thrombosis, 2015, Aug-26, Volume: 22, Issue:8

    Topics: Adult; Age Factors; Aged; Asian People; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Caroti

2015
High Uric Acid Levels During Pregnancy Linked to Increased Risk for Future Atherosclerotic-Related Hospitalization.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:6

    Topics: Adult; Atherosclerosis; Case-Control Studies; Female; Hospitalization; Humans; Israel; Pregnancy; Pr

2015
Factors influencing insulin resistance in relation to atherogenicity in mood disorders, the metabolic syndrome and tobacco use disorder.
    Journal of affective disorders, 2015, Jul-01, Volume: 179

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Biomarkers; Bipolar Disorder; Blood Glucose; Body Mass Ind

2015
Risk Factors for Subclinical Atherosclerosis and Uric Acid.
    Journal of atherosclerosis and thrombosis, 2015, Volume: 22, Issue:9

    Topics: Asian People; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Female; Huma

2015
Risk Factors for Subclinical Atherosclerosis and Uric Acid--Reply.
    Journal of atherosclerosis and thrombosis, 2015, Volume: 22, Issue:9

    Topics: Asian People; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Female; Huma

2015
Nephrolithiasis as a Risk Factor for CKD: The Atherosclerosis Risk in Communities Study.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Nov-06, Volume: 10, Issue:11

    Topics: Atherosclerosis; Female; Humans; Male; Middle Aged; Nephrolithiasis; Prospective Studies; Renal Insu

2015
Metabolic syndrome is associated with decreased circulating endothelial progenitor cells and increased arterial stiffness in systemic lupus erythematosus.
    Lupus, 2016, Volume: 25, Issue:2

    Topics: Adult; Aged; Arteries; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies

2016
Losartan alleviates hyperuricemia-induced atherosclerosis in a rabbit model.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:9

    Topics: Animals; Antihypertensive Agents; Aorta; Atherosclerosis; Blotting, Western; Disease Models, Animal;

2015
Gout in Older Adults: The Atherosclerosis Risk in Communities Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2016, Volume: 71, Issue:4

    Topics: Age Factors; Aged; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Bin

2016
Atherogenic index of plasma and risk of cardiovascular disease among Cameroonian postmenopausal women.
    Lipids in health and disease, 2016, Mar-09, Volume: 15

    Topics: Aged; Atherosclerosis; Blood Glucose; Blood Pressure; Cameroon; Cardiovascular Diseases; Cholesterol

2016
Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats.
    European journal of pharmacology, 2016, May-15, Volume: 779

    Topics: Animals; Atherosclerosis; Bilirubin; Blood Glucose; Body Weight; Carbamates; Creatinine; Diabetes Me

2016
Iterative Outlier Removal: A Method for Identifying Outliers in Laboratory Recalibration Studies.
    Clinical chemistry, 2016, Volume: 62, Issue:7

    Topics: Atherosclerosis; Calibration; Clinical Laboratory Techniques; Data Interpretation, Statistical; Huma

2016
Serum uric acid, gout, and venous thromboembolism: The atherosclerosis risk in communities study.
    Thrombosis research, 2016, Volume: 144

    Topics: Atherosclerosis; Biomarkers; Female; Gout; Humans; Middle Aged; Prospective Studies; Risk Factors; U

2016
Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ.
    Journal of receptor and signal transduction research, 2017, Volume: 37, Issue:2

    Topics: Angiotensin II; Animals; Atherosclerosis; Cardiovascular Diseases; Cell Proliferation; Gene Expressi

2017
Serum Total Sialic Acid Level is Elevated in Hypothyroid Patients as an Atherosclerotic Risk Factor.
    Journal of clinical laboratory analysis, 2017, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Atherosclerosis; Autoantibodies; Biomarkers; C-Reactive Protein; Cardiovascular D

2017
Atherogenic Index of Plasma Predicts Hyperuricemia in Rural Population: A Cross-Sectional Study from Northeast China.
    International journal of environmental research and public health, 2016, 09-02, Volume: 13, Issue:9

    Topics: Adult; Atherosclerosis; China; Cross-Sectional Studies; Female; Humans; Hyperuricemia; Male; Middle

2016
Are atherosclerotic risk factors associated with a poor prognosis in patients with hyperuricemic acute heart failure? The evaluation of the causal dependence of acute heart failure and hyperuricemia.
    Heart and vessels, 2017, Volume: 32, Issue:4

    Topics: Acute Disease; Aged; Atherosclerosis; Cause of Death; Female; Heart Failure; Humans; Hyperuricemia;

2017
Insulin resistance, atherogenicity, and iron metabolism in multiple sclerosis with and without depression: Associations with inflammatory and oxidative stress biomarkers and uric acid.
    Psychiatry research, 2017, Volume: 250

    Topics: Adult; Atherosclerosis; Biomarkers; C-Reactive Protein; Case-Control Studies; Depressive Disorder; F

2017
Clinical usefulness of metabolic risk factors to identify young asymptomatic women adults with subclinical atherosclerosis: A cross-sectional study.
    Medicine, 2017, Volume: 96, Issue:11

    Topics: Adult; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cross-Sectional Studies; Fema

2017
Apple polyphenols and fibers attenuate atherosclerosis in apolipoprotein E-deficient mice.
    Journal of agricultural and food chemistry, 2008, Jul-23, Volume: 56, Issue:14

    Topics: Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Dietary Fiber; Flavonoids; Fruit; Lipids;

2008
High serum uric acid and low-grade inflammation are associated with smaller LDL and HDL particles.
    Atherosclerosis, 2009, Volume: 203, Issue:1

    Topics: Adult; Atherosclerosis; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Female; Fibrinogen;

2009
Asymptomatic hyperuricemia and serum uric acid concentration correlate with subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease.
    Seminars in arthritis and rheumatism, 2009, Volume: 39, Issue:3

    Topics: Adult; Aged; Arthritis, Psoriatic; Atherosclerosis; Biomarkers; Carotid Arteries; Cohort Studies; Fe

2009
Edible mushroom Agaricus sylvaticus can prevent the onset of atheroma plaques in hipercholesterolemic rabbits.
    Cellular and molecular biology (Noisy-le-Grand, France), 2008, Nov-17, Volume: 54 Suppl

    Topics: Agaricus; Animals; Antioxidants; Aorta; Atherosclerosis; Cholesterol, Dietary; Hypercholesterolemia;

2008
Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study.
    American journal of epidemiology, 2009, May-01, Volume: 169, Issue:9

    Topics: Antiparkinson Agents; Atherosclerosis; Biomarkers; Black or African American; Cohort Studies; Commun

2009
Role of asymptomatic hyperuricemia and serum uric acid levels in the pathogenesis of subclinical atherosclerosis in psoriatic arthritis: comment on the article by Chen et al.
    Arthritis and rheumatism, 2009, Jun-15, Volume: 61, Issue:6

    Topics: Arthritis, Psoriatic; Atherosclerosis; Cohort Studies; Comorbidity; Female; Humans; Hyperuricemia; M

2009
Sex and age interaction with genetic association of atherogenic uric acid concentrations.
    Atherosclerosis, 2010, Volume: 210, Issue:2

    Topics: Age Factors; Aged; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Bin

2010
Correlation of asymptomatic hyperuricaemia and serum uric acid levels with arterial stiffness in women with systemic lupus erythematosus without clinically evident atherosclerotic cardiovascular disease.
    Lupus, 2010, Volume: 19, Issue:5

    Topics: Adult; Arteries; Atherosclerosis; Cross-Sectional Studies; Female; Humans; Lupus Erythematosus, Syst

2010
Role of uric acid in the link between arterial stiffness and cardiac hypertrophy: a cross-sectional study.
    Rheumatology (Oxford, England), 2010, Volume: 49, Issue:6

    Topics: Adult; Age Factors; Aged; Atherosclerosis; Cardiomegaly; Cross-Sectional Studies; Female; Humans; Hy

2010
Association of homocysteine with traditional and non-traditional risk factors in patients with atherosclerotic vascular disease.
    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2011, Volume: 8, Issue:1

    Topics: Atherosclerosis; C-Reactive Protein; Female; Homocysteine; Humans; Lipids; Male; Middle Aged; Risk F

2011
Factors associated with early atherosclerosis and arterial calcifications in young subjects with a benign phenotype of obesity.
    Obesity (Silver Spring, Md.), 2011, Volume: 19, Issue:8

    Topics: Adiponectin; Adolescent; Atherosclerosis; Biomarkers; Calcium; Carotid Arteries; Child; Cholesterol,

2011
Oxidative stress and endothelin-1 in atherosclerotic renal artery stenosis and effects of renal angioplasty.
    Kidney & blood pressure research, 2011, Volume: 34, Issue:6

    Topics: Aged; Angioplasty; Atherosclerosis; Biomarkers; Endothelin-1; Female; Humans; Hypertension; Male; Mi

2011
Risk profile in chronic kidney disease stage 3: older versus younger patients.
    Nephron. Clinical practice, 2011, Volume: 119, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Albuminuria; Atherosclerosis; Cardiovascular Diseases; Diabeti

2011
Serum uric acid: a marker of metabolic syndrome and subclinical atherosclerosis in Korean men.
    Angiology, 2012, Volume: 63, Issue:6

    Topics: Atherosclerosis; Biomarkers; Body Mass Index; Calcinosis; Carotid Intima-Media Thickness; Coronary A

2012
Serum uric acid is related to cardiovascular events and correlates with N-terminal pro-B-type natriuretic peptide and albuminuria in patients with diabetes mellitus.
    Diabetic medicine : a journal of the British Diabetic Association, 2012, Volume: 29, Issue:6

    Topics: Albuminuria; Atherosclerosis; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic

2012
Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis.
    Epilepsia, 2012, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Atherosclerosis; Blood Glucose; Carbamazepine; Carotid Art

2012
Uric acid is an important predictor for hypertensive early atherosclerosis.
    Advances in therapy, 2012, Volume: 29, Issue:3

    Topics: Adult; Atherosclerosis; Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Intima-Media Thick

2012
Cardiac biomarkers and noninvasive predictors of atherosclerosis in chronic peritoneal dialysis patients.
    Kidney & blood pressure research, 2012, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Biomarkers; Blood Flow Velocity; C-Reactive Protein; Carot

2012
[Uric acid, atherosclerosis and vascular calcifications in chronic kidney disease].
    Investigacion clinica, 2012, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Atherosclerosis; Calcinosis; Cardiovascular Diseases; Chronic Disease; Como

2012
[Clinical significance of insulin resistance syndrome in development of endothelial dysfunction in patients with primary gout].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2012, Issue:2

    Topics: Adult; Atherosclerosis; Blood Glucose; Brachial Artery; Carbohydrate Metabolism; Disease Progression

2012
Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study.
    Atherosclerosis, 2012, Volume: 223, Issue:2

    Topics: Adult; Age Factors; Asymptomatic Diseases; Atherosclerosis; Biomarkers; Body Mass Index; Cardiovascu

2012
Biochemical indicators of atherogenic and protective activity of xydiphone in experimental animals.
    Bulletin of experimental biology and medicine, 2012, Volume: 153, Issue:4

    Topics: Alkaline Phosphatase; Animals; Atherosclerosis; Biomarkers; Cholesterol, LDL; Creatine Kinase; Creat

2012
Serum uric acid: marker for atherosclerosis as it is positively associated with "atherogenic index of plasma".
    Archives of physiology and biochemistry, 2013, Volume: 119, Issue:1

    Topics: Adult; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Humans; India

2013
Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis.
    Journal of cardiology, 2013, Volume: 61, Issue:2

    Topics: Adult; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Biomarkers; C-Reactive Protein; Carotid Ar

2013
Synergistic effects of serum uric acid and cardiometabolic risk factors on early stage atherosclerosis: the cardiometabolic risk in Chinese study.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; China; Female; Heart; Human

2012
[Hepatocatalase: biochemical and pharmacological properties. Its relation with atherosclerosis].
    Archives des maladies du coeur et des vaisseaux, 1963, Volume: 5(Suppl 1)

    Topics: Arteriosclerosis; Atherosclerosis; Catalase; Cholesterol; Granuloma; Humans; Uric Acid

1963
"ATROMID" IN ATHEROSCLEROSIS.
    The Medical journal of Australia, 1964, Jul-04, Volume: 2

    Topics: Androsterone; Angina Pectoris; Arteriosclerosis Obliterans; Atherosclerosis; Blood Chemical Analysis

1964
[BLOOD CHOLESTEROL AND TRIGLYCERIDES IN 2 OCCUPATIONAL GROUPS. FIRST RESULTS OF AN EPIDEMIOLOGIC INVESTIGATION ON THE FACTORS OF ATHEROSCLEROSIS].
    Revue de l'atherosclerose, 1964, Volume: 6

    Topics: Adolescent; Aging; Arteriosclerosis; Atherosclerosis; Blood; Blood Pressure; Body Weight; Cholestero

1964
Relationships of C-reactive protein, uric acid, and glomerular filtration rate to arterial stiffness in Japanese subjects.
    Journal of human hypertension, 2005, Volume: 19, Issue:11

    Topics: Adult; Ankle; Atherosclerosis; Blood Flow Velocity; Blood Pressure; Brachial Artery; C-Reactive Prot

2005
Relationship of serum uric acid to measures of endothelial function and atherosclerosis in healthy adults.
    International journal of clinical practice, 2005, Volume: 59, Issue:11

    Topics: Adult; Aorta, Thoracic; Atherosclerosis; Brachial Artery; Carotid Artery, Common; Endothelium, Vascu

2005
The inverse relationship between thoracic aortic intima media thickness and testosterone level.
    Endocrine research, 2005, Volume: 31, Issue:4

    Topics: Adult; Aged; Aorta, Thoracic; Atherosclerosis; C-Reactive Protein; Echocardiography, Transesophageal

2005
Uric acid and inflammatory markers.
    European heart journal, 2006, Volume: 27, Issue:10

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Biomarkers; C-Reactive Protein; Cytokines; Female; Humans;

2006
Higher serum uric acid is associated with increased arterial stiffness in Japanese individuals.
    Atherosclerosis, 2007, Volume: 192, Issue:1

    Topics: Aged; Atherosclerosis; Brachial Artery; Carotid Arteries; Carotid Artery Diseases; Elasticity; Femal

2007
Significance of uric acid for the heart and vessels.
    European heart journal, 2006, Volume: 27, Issue:15

    Topics: Atherosclerosis; Biomarkers; Humans; Uric Acid

2006
Serum uric acid predicts incident hypertension in a biethnic cohort: the atherosclerosis risk in communities study.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:6

    Topics: Atherosclerosis; Black or African American; Cohort Studies; Female; Follow-Up Studies; Humans; Hyper

2006
[Metabolic syndrome complicated by peripheral arterial disease: clinical study of 2115 cases].
    Zhonghua yi xue za zhi, 2006, Aug-15, Volume: 86, Issue:30

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Blood Glucose; Blood Urea Nitrogen; Body Mass Index

2006
Non-traditional markers of atherosclerosis potentiate the risk of coronary heart disease in patients with type 2 diabetes and metabolic syndrome.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2008, Volume: 18, Issue:1

    Topics: Aged; Atherosclerosis; Biomarkers; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease

2008
Vascular risk factors and oxidative stress as independent predictors of asymptomatic atherosclerosis in adult patients with epilepsy.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Adult; Anticonvulsants; Antioxidants; Atherosclerosis; Blood Glucose; Carotid Arteries; Cholesterol;

2007
[Chronic asymptomatic hyperuricemia as a marker of atherogenic risk in children].
    Kardiologiia, 2007, Volume: 47, Issue:3

    Topics: Adolescent; Age Factors; Atherosclerosis; Biomarkers; Blood Glucose; Blood Pressure; Chi-Square Dist

2007
Effects of serum levels of novel atherosclerotic risk factors on aortic valve calcification.
    The Journal of heart valve disease, 2007, Volume: 16, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Aortic Valve; Atherosclerosis; C-Reactive Protein; Calcinosis;

2007
Association of D-dimer with microalbuminuria in patients with type 2 diabetes mellitus.
    Journal of thrombosis and thrombolysis, 2009, Volume: 27, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Atherosclerosis; Biomarkers; Body Mass Index; Carotid A

2009
Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitus.
    Metabolism: clinical and experimental, 2008, Volume: 57, Issue:5

    Topics: Aged; Albuminuria; Atherosclerosis; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemo

2008