uric acid has been researched along with Atheroma in 25 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum uric acid increases with metabolic disorders; however, whether the effects of uric acid on atherosclerosis are different in females and males has not been sufficiently evaluated." | 8.12 | Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females. ( Dohi, Y; Iwase, M; Nagami, T; Ohte, N; Seo, Y; Sugiura, T; Suzuki, K; Takagi, Y; Takase, H; Tomiishi, T; Yokochi, T; Yoshikane, N, 2022) |
| "The data indicate that the development of atherosclerosis and inflammation is promoted by uric acid in vivo." | 7.96 | Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. ( Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T, 2020) |
| "Elevated serum uric acid (SUA) level is known to be a prognostic factor in patients with acute coronary syndrome (ACS)." | 7.88 | Correlation of Serum Uric Acid Levels with Nonculprit Plaque Instability in Patients with Acute Coronary Syndromes: A 3-Vessel Optical Coherence Tomography Study. ( Lin, L; Wang, N; Yu, B; Zhang, D; Zhang, R, 2018) |
| "To explore the associations between urine uric acid excretion (UUAE) and diabetic retinopathy (DR)/lower limb atherosclerotic lesions in hospitalized Chinese patients with type 2 diabetes." | 7.81 | Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes. ( Bao, YQ; Chen, MY; Jia, WP; Li, LX; Li, TT; Lu, JX; Shuai, HP; Wang, JW; Xia, HF; Zhang, R, 2015) |
| "Although many studies have examined the relationship between uric acid (UA) and coronary artery disease (CAD), whether UA is an independent risk factor contributing to progression of CAD is still controversial." | 7.80 | A cross-sectional analysis of the relationship between uric acid and coronary atherosclerosis in patients with suspected coronary artery disease in China. ( Chen, L; Geng, S; Li, H; Liu, T; Qi, G; Sun, Y; Wu, C; Xu, K; Yu, X; Zhi, Y, 2014) |
| " Based on preclinical and clinical evidences, this review discusses: (i) stone forming risk factors, crystal nucleation, aggregation, injury-induced crystal retention, and stone formation, (ii) CVD risk factors such as dyslipidemia, perturbation of gut microbiome, obesity, free radical-induced lipoprotein oxidation, and retention in the arterial wall, subsequent foam cell formation, and atherosclerosis, (iii) mechanism by which stone forming risk factors such as oxalate, calcium, uric acid, and infection contribute toward CVDs, and (iv) how CVD risk factors, such as cholesterol, phospholipids, and uric acid, contribute to kidney stone formation are described." | 4.98 | Cross-talk between renal lithogenesis and atherosclerosis: an unveiled link between kidney stone formation and cardiovascular diseases. ( Devarajan, A, 2018) |
| "Serum uric acid increases with metabolic disorders; however, whether the effects of uric acid on atherosclerosis are different in females and males has not been sufficiently evaluated." | 4.12 | Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females. ( Dohi, Y; Iwase, M; Nagami, T; Ohte, N; Seo, Y; Sugiura, T; Suzuki, K; Takagi, Y; Takase, H; Tomiishi, T; Yokochi, T; Yoshikane, N, 2022) |
| "The data indicate that the development of atherosclerosis and inflammation is promoted by uric acid in vivo." | 3.96 | Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. ( Hosoyamada, M; Kimura, Y; Kono, H; Onda, A; Tsukui, D; Yanagida, T, 2020) |
| "Elevated serum uric acid (SUA) level is known to be a prognostic factor in patients with acute coronary syndrome (ACS)." | 3.88 | Correlation of Serum Uric Acid Levels with Nonculprit Plaque Instability in Patients with Acute Coronary Syndromes: A 3-Vessel Optical Coherence Tomography Study. ( Lin, L; Wang, N; Yu, B; Zhang, D; Zhang, R, 2018) |
| "To explore the associations between urine uric acid excretion (UUAE) and diabetic retinopathy (DR)/lower limb atherosclerotic lesions in hospitalized Chinese patients with type 2 diabetes." | 3.81 | Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes. ( Bao, YQ; Chen, MY; Jia, WP; Li, LX; Li, TT; Lu, JX; Shuai, HP; Wang, JW; Xia, HF; Zhang, R, 2015) |
| "Elevated serum uric acid (SUA) level is known to be a prognostic factor in patients with acute coronary syndrome (ACS)." | 3.81 | Relation of Lipid Content of Coronary Plaque to Level of Serum Uric Acid. ( Fujimoto, Y; Kobayashi, Y; Nakayama, T; Saito, Y; Sugimoto, K, 2015) |
| "Although many studies have examined the relationship between uric acid (UA) and coronary artery disease (CAD), whether UA is an independent risk factor contributing to progression of CAD is still controversial." | 3.80 | A cross-sectional analysis of the relationship between uric acid and coronary atherosclerosis in patients with suspected coronary artery disease in China. ( Chen, L; Geng, S; Li, H; Liu, T; Qi, G; Sun, Y; Wu, C; Xu, K; Yu, X; Zhi, Y, 2014) |
| "Acute rupture or erosion of unstable atherosclerotic plaques is a major cause of adverse consequences of atherosclerotic cardiovascular disease, often leading to myocardial infarction or stroke." | 1.91 | High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy. ( Chen, B; Cheng, J; He, F; Koyama, H; Liu, W; Lv, J; Wang, Q; Xu, C; Yamamoto, T; Yu, W; Zhao, H, 2023) |
| "Hyperuricemia was associated with greater NLRP3 and gasdermin-D expression on human atheroma plaques in patients with peripheral artery disease." | 1.72 | Birefringent crystals deposition and inflammasome expression in human atheroma plaques by levels of uricemia. ( Andrés, M; Argente-Del-Castillo, E; Mendieta, L; Miñano, A; Pascual, E; Trigueros, M, 2022) |
| "Coronary atherosclerotic plaques (calcified, mixed, and non-calcified plaques) were assessed using CCTA." | 1.51 | Serum uric acid level and subclinical coronary atherosclerosis in asymptomatic individuals: An observational cohort study. ( Choe, J; Choi, SW; Hong, S; Kang, JW; Kim, HK; Kim, YG; Kim, YH; Lee, CK; Lee, SW; Lee, Y; Lim, DH; Lim, TH; Park, GM; Yang, DH; Yoo, B, 2019) |
| "Atherosclerosis is considered as an inflammatory disease, and carotid artery intima-media thickness (IMT) and carotid plaque are generally used as intermediated phenotype of atherosclerosis." | 1.42 | Association of interleukin-10 promoter region polymorphisms with risk factors of Atherosclerosis. ( Cho, HC; Chung, IS; Chung, JH; Jun, SE; Park, KO; Shin, DH; Yu, GI, 2015) |
| "The total burden of subclinical coronary atherosclerosis is significant in young adults." | 1.42 | Evaluation of lipoprotein-associated phosholipase A2 and plaque burden/composition in young adults. ( Akin, F; Akturk, F; Ayca, B; Birand, A; Celik, O; Erturk, M; Kaya, MG; Ozturk, D; Pusuroglu, H; Satilmis, S; Yalcin, AA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 18 (72.00) | 24.3611 |
| 2020's | 7 (28.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, Y | 1 |
| Qing, J | 1 |
| Wu, G | 1 |
| Li, X | 1 |
| Guo, F | 1 |
| Wang, Y | 2 |
| Wang, L | 1 |
| Li, M | 1 |
| Sugiura, T | 1 |
| Dohi, Y | 1 |
| Takagi, Y | 1 |
| Yokochi, T | 1 |
| Yoshikane, N | 1 |
| Suzuki, K | 1 |
| Tomiishi, T | 1 |
| Nagami, T | 1 |
| Iwase, M | 1 |
| Takase, H | 1 |
| Ohte, N | 1 |
| Seo, Y | 1 |
| Yu, W | 4 |
| Liu, W | 4 |
| Wang, Q | 4 |
| Xu, C | 4 |
| Zhao, H | 4 |
| Lv, J | 4 |
| He, F | 4 |
| Chen, B | 4 |
| Yamamoto, T | 4 |
| Koyama, H | 4 |
| Cheng, J | 4 |
| Andrés, M | 1 |
| Mendieta, L | 1 |
| Argente-Del-Castillo, E | 1 |
| Trigueros, M | 1 |
| Miñano, A | 1 |
| Pascual, E | 1 |
| Chu, X | 1 |
| Lu, Y | 1 |
| Mei, M | 1 |
| Peng, P | 1 |
| Zhao, Y | 1 |
| Fu, G | 1 |
| Qiu, F | 1 |
| Jin, C | 1 |
| Kimura, Y | 1 |
| Yanagida, T | 1 |
| Onda, A | 1 |
| Tsukui, D | 1 |
| Hosoyamada, M | 1 |
| Kono, H | 1 |
| Zhang, H | 1 |
| Devarajan, A | 1 |
| Zhang, D | 1 |
| Zhang, R | 2 |
| Wang, N | 1 |
| Lin, L | 1 |
| Yu, B | 1 |
| Lv, S | 1 |
| Ohene, BE | 1 |
| Zhou, Y | 2 |
| Lim, DH | 1 |
| Lee, Y | 1 |
| Park, GM | 1 |
| Choi, SW | 1 |
| Kim, YG | 2 |
| Lee, SW | 1 |
| Kim, YH | 1 |
| Yang, DH | 1 |
| Kang, JW | 1 |
| Lim, TH | 1 |
| Kim, HK | 1 |
| Choe, J | 1 |
| Hong, S | 1 |
| Lee, CK | 1 |
| Yoo, B | 1 |
| Tan, C | 1 |
| Liu, Y | 1 |
| Li, W | 1 |
| Deng, F | 1 |
| Liu, X | 1 |
| Wang, X | 1 |
| Gui, Y | 1 |
| Qin, L | 1 |
| Hu, C | 1 |
| Chen, L | 2 |
| Sun, Y | 1 |
| Yu, X | 1 |
| Zhi, Y | 1 |
| Geng, S | 1 |
| Li, H | 1 |
| Liu, T | 1 |
| Xu, K | 1 |
| Wu, C | 1 |
| Qi, G | 1 |
| Yu, GI | 1 |
| Jun, SE | 1 |
| Cho, HC | 1 |
| Park, KO | 1 |
| Chung, JH | 1 |
| Shin, DH | 1 |
| Chung, IS | 1 |
| Celik, O | 1 |
| Ozturk, D | 1 |
| Akin, F | 1 |
| Satilmis, S | 1 |
| Yalcin, AA | 1 |
| Erturk, M | 1 |
| Ayca, B | 1 |
| Akturk, F | 1 |
| Birand, A | 1 |
| Pusuroglu, H | 1 |
| Kaya, MG | 1 |
| Kawada, T | 1 |
| Andou, T | 1 |
| Fukumitsu, M | 1 |
| Li, Q | 1 |
| Dong, K | 1 |
| Wang, A | 1 |
| Yang, X | 1 |
| Zhang, C | 1 |
| Zhu, Y | 1 |
| Wu, S | 1 |
| Zhao, X | 1 |
| Li, LX | 1 |
| Lu, JX | 1 |
| Shuai, HP | 1 |
| Xia, HF | 1 |
| Wang, JW | 1 |
| Chen, MY | 1 |
| Li, TT | 1 |
| Bao, YQ | 1 |
| Jia, WP | 1 |
| Saito, Y | 1 |
| Nakayama, T | 1 |
| Sugimoto, K | 1 |
| Fujimoto, Y | 1 |
| Kobayashi, Y | 1 |
| Ando, K | 1 |
| Takahashi, H | 1 |
| Watanabe, T | 1 |
| Daidoji, H | 1 |
| Otaki, Y | 1 |
| Nishiyama, S | 1 |
| Arimoto, T | 1 |
| Shishido, T | 1 |
| Miyashita, T | 1 |
| Miyamoto, T | 1 |
| Kubota, I | 1 |
| Kawasaki, M | 1 |
| Lee, JH | 1 |
| Kang, YS | 1 |
| Jeong, YJ | 1 |
| Yoon, YS | 1 |
| Kwack, WG | 1 |
| Oh, JY | 1 |
| Iwata, A | 1 |
| Miura, S | 1 |
| Tanaka, T | 1 |
| Ike, A | 1 |
| Sugihara, M | 1 |
| Nishikawa, H | 1 |
| Kawamura, A | 1 |
| Saku, K | 1 |
| Jiang, S | 1 |
| Sun, X | 1 |
| Gu, H | 1 |
| Chen, Y | 1 |
| Xi, C | 1 |
| Qiao, X | 1 |
| Chen, X | 1 |
1 review available for uric acid and Atheroma
| Article | Year |
|---|---|
Cross-talk between renal lithogenesis and atherosclerosis: an unveiled link between kidney stone formation and cardiovascular diseases.
Topics: Animals; Arteries; Atherosclerosis; Calcium; Crystallization; Humans; Kidney; Kidney Calculi; Lipids | 2018 |
1 trial available for uric acid and Atheroma
| Article | Year |
|---|---|
The Association between Serum Uric Acid Levels and the Prevalence of Vulnerable Atherosclerotic Carotid Plaque: A Cross-sectional Study.
Topics: Adult; Aged; Carotid Artery Diseases; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Pl | 2015 |
23 other studies available for uric acid and Atheroma
| Article | Year |
|---|---|
Correlation between serum uric acid levels and carotid plaque neovascularisation assessed by contrast-enhanced ultrasound.
Topics: Aged; Carotid Stenosis; Cohort Studies; Female; Humans; Male; Middle Aged; Neovascularization, Patho | 2021 |
Increased Impact of Serum Uric Acid on Arterial Stiffness and Atherosclerosis in Females.
Topics: Atherosclerosis; Carotid Arteries; Carotid Intima-Media Thickness; Female; Humans; Male; Middle Aged | 2022 |
High Level of Uric Acid Promotes Atherosclerosis by Targeting NRF2-Mediated Autophagy Dysfunction and Ferroptosis.
Topics: Animals; Atherosclerosis; Autophagy; Ferroptosis; Hyperuricemia; Mice; NF-E2-Related Factor 2; Plaqu | 2022 |
Birefringent crystals deposition and inflammasome expression in human atheroma plaques by levels of uricemia.
Topics: Caspase 1; Ethanol; Gout; Humans; Hyperuricemia; Inflammasomes; Interleukin-1beta; NLR Family, Pyrin | 2022 |
Correlation Between Serum Uric Acid Levels and Coronary Plaque Characteristics on Optical Coherence Tomography.
Topics: Acute Coronary Syndrome; Calcinosis; Coronary Angiography; Coronary Artery Disease; Coronary Vessels | 2022 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy.
Topics: Animals; Apoptosis; Atherosclerosis; Autophagy; Mice; Mice, Knockout; Plaque, Atherosclerotic; Uric | 2023 |
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Topics: Adult; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Benzbromarone; Biomarkers; Disease M | 2020 |
Serum 25-Hydroxyvitamin D3 Levels Are Associated with Carotid Intima-Media Thickness and Carotid Atherosclerotic Plaque in Type 2 Diabetic Patients.
Topics: Adult; Blood Glucose; Calcifediol; Calcium; Carotid Artery Diseases; Carotid Intima-Media Thickness; | 2017 |
Correlation of Serum Uric Acid Levels with Nonculprit Plaque Instability in Patients with Acute Coronary Syndromes: A 3-Vessel Optical Coherence Tomography Study.
Topics: Acute Coronary Syndrome; Aged; Coronary Vessels; Female; Humans; Lipids; Macrophages; Male; Middle A | 2018 |
Very High Serum Uric Acid Levels, Plaque Morphology, and the Acute Coronary Syndrome.
Topics: Acute Coronary Syndrome; Coronary Artery Disease; Humans; Plaque, Atherosclerotic; Tomography, Optic | 2018 |
Serum uric acid level and subclinical coronary atherosclerosis in asymptomatic individuals: An observational cohort study.
Topics: Asymptomatic Diseases; Biomarkers; Computed Tomography Angiography; Coronary Angiography; Coronary A | 2019 |
Associations of matrix metalloproteinase-9 and monocyte chemoattractant protein-1 concentrations with carotid atherosclerosis, based on measurements of plaque and intima-media thickness.
Topics: Adult; Aged; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Chemokine CC | 2014 |
A cross-sectional analysis of the relationship between uric acid and coronary atherosclerosis in patients with suspected coronary artery disease in China.
Topics: Aged; Biomarkers; Chi-Square Distribution; China; Coronary Angiography; Coronary Artery Disease; Cor | 2014 |
Association of interleukin-10 promoter region polymorphisms with risk factors of Atherosclerosis.
Topics: Atherosclerosis; Blood Pressure; Carotid Intima-Media Thickness; Cholesterol; Female; Homocysteine; | 2015 |
Evaluation of lipoprotein-associated phosholipase A2 and plaque burden/composition in young adults.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Age Factors; Biomarkers; C-Reactive Protein; | 2015 |
Metabolic syndrome showed significant relationship with carotid atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Artery Dis | 2016 |
Decreased urine uric acid excretion is associated with diabetic retinopathy but not with lower limb atherosclerosis in hospitalized patients with type 2 diabetes.
Topics: Aged; Alcohol Drinking; Biomarkers; China; Comorbidity; Constriction, Pathologic; Cross-Sectional St | 2015 |
Relation of Lipid Content of Coronary Plaque to Level of Serum Uric Acid.
Topics: Acute Coronary Syndrome; Aged; Biomarkers; Body Mass Index; Calcinosis; Female; Hospitals, Universit | 2015 |
Impact of Serum Uric Acid Levels on Coronary Plaque Stability Evaluated Using Integrated Backscatter Intravascular Ultrasound in Patients with Coronary Artery Disease.
Topics: Aged; Coronary Artery Disease; Female; Humans; Image Interpretation, Computer-Assisted; Japan; Male; | 2016 |
Tissue Characterization of Coronary Plaques as a Key to Relationship between Serum Uric Acid Level and Cardiovascular Disease: A Direct Risk or an Indirect Marker?
Topics: Biomarkers; Cardiovascular Diseases; Humans; Plaque, Atherosclerotic; Tissue Distribution; Ultrasono | 2016 |
Relationship between FEV1 and Cardiovascular Risk Factors in General Population without Airflow Limitation.
Topics: Adult; Age Factors; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Carotid Artery Dise | 2016 |
Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin.
Topics: Aged; Angina, Stable; Atorvastatin; Biomarkers; C-Reactive Protein; Case-Control Studies; Chi-Square | 2012 |
Age-related change in kidney function, its influencing factors, and association with asymptomatic carotid atherosclerosis in healthy individuals--a 5-year follow-up study.
Topics: Age Factors; Aged; Aging; Blood Pressure; Carotid Artery Diseases; China; Cholesterol, LDL; Cross-Se | 2012 |