uric acid has been researched along with Arterial Diseases, Carotid in 58 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In Japanese patients with asymptomatic hyperuricemia, 24 months of febuxostat treatment did not delay carotid atherosclerosis progression, compared with non-pharmacological care." | 9.34 | Febuxostat does not delay progression of carotid atherosclerosis in patients with asymptomatic hyperuricemia: A randomized, controlled trial. ( Eguchi, K; Higashi, Y; Ishibashi, R; Ishizaka, N; Ishizu, T; Kanzaki, Y; Kario, K; Kato, T; Maemura, K; Murohara, T; Node, K; Ohishi, M; Oyama, JI; Sata, M; Sezai, A; Taguchi, I; Tanaka, A; Teragawa, H; Tomiyama, H; Toyoda, S; Ueda, S; Yamada, H; Yokote, K, 2020) |
| "The European Lacidipine Study on Atherosclerosis (ELSA) was a randomized, double-blind, multicenter trial comparing the effects of a 4-year treatment with either lacidipine or atenolol on progression of carotid atherosclerosis in patients with moderate hypertension." | 9.30 | Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis. ( Bombelli, M; Cuspidi, C; Facchetti, R; Grassi, G; Macchiarulo, M; Maggiolini, D; Mancia, G; Parati, G, 2019) |
| "It is still undefined whether serum uric acid (SUA) is an independent risk factor for target organ damage (TOD) and cardiovascular events in human hypertension." | 9.12 | Lack of association between serum uric acid and organ damage in a never-treated essential hypertensive population at low prevalence of hyperuricemia. ( Cuspidi, C; Esposito, A; Mancia, G; Meani, S; Sala, C; Valerio, C; Zanchetti, A, 2007) |
| "Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with atherosclerosis, respectively." | 8.12 | Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. ( Dong, H; Hu, X; Li, G; Li, W; Liu, J; Wang, C; Zhou, Y, 2022) |
| "Serum uric acid (SUA) is associated with many cardiovascular risk factors, such as metabolic syndrome (MetS) and subclinical atherosclerosis." | 8.12 | Association Between Serum Uric Acid Level and Carotid Atherosclerosis and Metabolic Syndrome in Patients With Type 2 Diabetes Mellitus. ( Li, M; Li, T; Li, W; Liu, R; Liu, S; Liu, X; Ouyang, S; Wang, Y; Zhang, Y, 2022) |
| "The association between serum uric acid (UA) and atherosclerosis in old people is controversial." | 8.02 | Association between uric acid and atherosclerosis in community-dwelling older people: The SONIC study. ( Akagi, Y; Akasaka, H; Arai, Y; Godai, K; Gondo, Y; Ikebe, K; Ishizaki, T; Kabayama, M; Kamide, K; Kiyoshige, E; Masui, Y; Rakugi, H; Sekiguchi, T; Sugimoto, K; Takami, Y; Takeya, Y; Tanaka, K; Yamamoto, K; Yasumoto, S, 2021) |
| "Heterogeneous results have been obtained in the relationship between serum uric acid (SUA) and target organ damage (TOD) in patients with hypertension." | 7.88 | Sex-related relationships between uric acid and target organ damage in hypertension. ( Casati, M; Falbo, R; Giannattasio, C; Grassi, G; Maggioni, S; Maloberti, A; Nava, S; Occhi, L; Panzeri, F; Signorini, S; Triglione, N, 2018) |
| " However, no data are available concerning the relationship between serum uric acid (UA) and subclinical thoracic aortic atherosclerosis." | 7.79 | Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis. ( Çaylı, M; Elbasan, Z; Gür, M; Kalkan, GY; Kaya, Z; Özaltun, B; Sahin, DY; Yıldız, A, 2013) |
| " Associations between uric acid (UA), metabolic syndrome (MetS) and carotid IMT have been reported, but findings regarding the relationship have been inconsistent." | 7.78 | Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome. ( Abe, M; Kawamoto, R; Kusunoki, T; Onji, M; Takayama, S, 2012) |
| "We aimed to investigate whether elevated serum uric acid concentrations are associated with higher risk of metabolic syndrome (MetS) and carotid atherosclerosis in patients with type 2 diabetes." | 7.77 | Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. ( Chen, L; He, M; Hu, R; Huang, Y; Li, Q; Lu, B; Qu, S; Tao, X; Wen, J; Yang, Z; Ye, Z; Zhang, W; Zhang, Z, 2011) |
| " After adjusting for age, total cholesterol, and smoking status, the odds ratios (95% CI) of sex-specific quartiles of serum uric acid for metabolic syndrome were 1." | 7.73 | Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals. ( Ishizaka, N; Ishizaka, Y; Nagai, R; Toda, E; Yamakado, M, 2005) |
| "In Japanese patients with asymptomatic hyperuricemia, 24 months of febuxostat treatment did not delay carotid atherosclerosis progression, compared with non-pharmacological care." | 5.34 | Febuxostat does not delay progression of carotid atherosclerosis in patients with asymptomatic hyperuricemia: A randomized, controlled trial. ( Eguchi, K; Higashi, Y; Ishibashi, R; Ishizaka, N; Ishizu, T; Kanzaki, Y; Kario, K; Kato, T; Maemura, K; Murohara, T; Node, K; Ohishi, M; Oyama, JI; Sata, M; Sezai, A; Taguchi, I; Tanaka, A; Teragawa, H; Tomiyama, H; Toyoda, S; Ueda, S; Yamada, H; Yokote, K, 2020) |
| "The European Lacidipine Study on Atherosclerosis (ELSA) was a randomized, double-blind, multicenter trial comparing the effects of a 4-year treatment with either lacidipine or atenolol on progression of carotid atherosclerosis in patients with moderate hypertension." | 5.30 | Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis. ( Bombelli, M; Cuspidi, C; Facchetti, R; Grassi, G; Macchiarulo, M; Maggiolini, D; Mancia, G; Parati, G, 2019) |
| " The keywords used to retrieve the literature were carotid intima thickness, intima-media thickness, carotid atherosclerosis, carotid stenosis, carotid artery, uric acid, blood uric acid, and hyperuricaemia." | 5.12 | Meta-analysis of the correlation between serum uric acid level and carotid intima-media thickness. ( Huang, W; Li, L; Ma, M; Mao, M; Peng, B; Wang, H; Wang, L; Zhong, X, 2021) |
| "It is still undefined whether serum uric acid (SUA) is an independent risk factor for target organ damage (TOD) and cardiovascular events in human hypertension." | 5.12 | Lack of association between serum uric acid and organ damage in a never-treated essential hypertensive population at low prevalence of hyperuricemia. ( Cuspidi, C; Esposito, A; Mancia, G; Meani, S; Sala, C; Valerio, C; Zanchetti, A, 2007) |
| "serum uric acid, but not the serum uric acid/creatinine ratio, results strongly influenced by the number of cardiovascular risk factors and by the insulin resistance degree." | 4.12 | Uric acid and uric acid/creatinine ratio and their correlations with the hemorheological determinants in subjects with subclinical carotid atherosclerosis. ( Amato, C; Brucculeri, S; Caimi, G; Carlisi, M; Lo Presti, R; Urso, C, 2022) |
| "Uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) are positively and negatively associated with atherosclerosis, respectively." | 4.12 | Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. ( Dong, H; Hu, X; Li, G; Li, W; Liu, J; Wang, C; Zhou, Y, 2022) |
| "Serum uric acid (SUA) is associated with many cardiovascular risk factors, such as metabolic syndrome (MetS) and subclinical atherosclerosis." | 4.12 | Association Between Serum Uric Acid Level and Carotid Atherosclerosis and Metabolic Syndrome in Patients With Type 2 Diabetes Mellitus. ( Li, M; Li, T; Li, W; Liu, R; Liu, S; Liu, X; Ouyang, S; Wang, Y; Zhang, Y, 2022) |
| "The association between serum uric acid (UA) and atherosclerosis in old people is controversial." | 4.02 | Association between uric acid and atherosclerosis in community-dwelling older people: The SONIC study. ( Akagi, Y; Akasaka, H; Arai, Y; Godai, K; Gondo, Y; Ikebe, K; Ishizaki, T; Kabayama, M; Kamide, K; Kiyoshige, E; Masui, Y; Rakugi, H; Sekiguchi, T; Sugimoto, K; Takami, Y; Takeya, Y; Tanaka, K; Yamamoto, K; Yasumoto, S, 2021) |
| "In patients with cerebral infarction (CI), elevated serum uric acid (UA) level may exacerbate the occurrence and development of carotid atherosclerosis (AS)." | 3.88 | Uric acid promotes oxidative stress and enhances vascular endothelial cell apoptosis in rats with middle cerebral artery occlusion. ( Song, C; Zhao, X, 2018) |
| "Heterogeneous results have been obtained in the relationship between serum uric acid (SUA) and target organ damage (TOD) in patients with hypertension." | 3.88 | Sex-related relationships between uric acid and target organ damage in hypertension. ( Casati, M; Falbo, R; Giannattasio, C; Grassi, G; Maggioni, S; Maloberti, A; Nava, S; Occhi, L; Panzeri, F; Signorini, S; Triglione, N, 2018) |
| " However, no data are available concerning the relationship between serum uric acid (UA) and subclinical thoracic aortic atherosclerosis." | 3.79 | Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis. ( Çaylı, M; Elbasan, Z; Gür, M; Kalkan, GY; Kaya, Z; Özaltun, B; Sahin, DY; Yıldız, A, 2013) |
| " Associations between uric acid (UA), metabolic syndrome (MetS) and carotid IMT have been reported, but findings regarding the relationship have been inconsistent." | 3.78 | Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome. ( Abe, M; Kawamoto, R; Kusunoki, T; Onji, M; Takayama, S, 2012) |
| "We aimed to investigate whether elevated serum uric acid concentrations are associated with higher risk of metabolic syndrome (MetS) and carotid atherosclerosis in patients with type 2 diabetes." | 3.77 | Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. ( Chen, L; He, M; Hu, R; Huang, Y; Li, Q; Lu, B; Qu, S; Tao, X; Wen, J; Yang, Z; Ye, Z; Zhang, W; Zhang, Z, 2011) |
| "To analyze the association of hyperuricemia with incidence of carotid plaque in general population and furthermore to explore the predictive value of serum uric acid in the early prevention of atherosclerotic disease." | 3.74 | [The association between hyperuricemia and prevalence of carotid plaque]. ( Li, Y; Li, ZA; Liu, J; Wang, W; Yong, Q; Zhao, D, 2008) |
| " After adjusting for age, total cholesterol, and smoking status, the odds ratios (95% CI) of sex-specific quartiles of serum uric acid for metabolic syndrome were 1." | 3.73 | Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals. ( Ishizaka, N; Ishizaka, Y; Nagai, R; Toda, E; Yamakado, M, 2005) |
| "Stroke was significantly associated with hypertension and high values of plasma glucose but not with fibrinogen, factor VIIc, or factor VIIIc." | 3.69 | Associations between carotid atherosclerosis and high factor VIII activity, dyslipidemia, and hypertension. ( Bai, CH; Chen, JR; Chiu, HC; Pan, WH, 1997) |
| " Abnormal angiograms were associated with greater age, treated hypertension, current smoking, and lower hemoglobin levels but with higher uric acid, factor VIII, and fibrinogen concentrations." | 3.67 | Arterial disease risk factors and angiographic evidence of atheroma of the carotid artery. ( Harrison, MJ; Hurst, C; Meade, TW; Schneidau, A; Wilkes, HC, 1989) |
| "Febuxostat is a selective xanthine oxidase inhibitor that reportedly exhibits antioxidant properties." | 3.30 | Effect of febuxostat on the level of malondialdehyde-modified low-density lipoprotein, an oxidative stress marker: A subanalysis of the PRIZE study. ( Bando, YK; Fujii, Y; Kadokami, T; Koide, H; Murohara, T; Node, K; Nomura, S; Saito, M; Sano, H; Tanaka, A; Teragawa, H; Ueda, T; Yoshida, H, 2023) |
| "In contrast, Uox-KO mice with carotid atherosclerosis showed severe neointimal changes in histology staining consistent with increases in intimal area and increases in proliferating cell nuclear antigen (PCNA)- and F4/80-positive cells." | 1.51 | Urate-lowering therapy alleviates atherosclerosis inflammatory response factors and neointimal lesions in a mouse model of induced carotid atherosclerosis. ( Ji, X; Li, C; Liu, Z; Lu, J; Merriman, TR; Qu, X; Sun, M; Wu, X; Yuan, X, 2019) |
| " The association of SUA with PLQ increased with increasing SUA levels, demonstrating a dose-response relation for men [OR 1." | 1.35 | Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study. ( Ellison, RC; Felson, DT; Hunt, S; Neogi, T; Terkeltaub, R; Zhang, Y, 2009) |
| "Hyperuricemia is postulated to be a risk factor for atherosclerotic diseases, although whether it is independent of classical atherogenic risk factors is controversial." | 1.34 | Higher serum uric acid is associated with increased arterial stiffness in Japanese individuals. ( Hashimoto, H; Ishizaka, N; Ishizaka, Y; Nagai, R; Toda, E; Yamakado, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.45) | 18.7374 |
| 1990's | 4 (6.90) | 18.2507 |
| 2000's | 14 (24.14) | 29.6817 |
| 2010's | 26 (44.83) | 24.3611 |
| 2020's | 12 (20.69) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, XK | 1 |
| Luo, D | 1 |
| Chen, WJ | 1 |
| Wang, RR | 1 |
| Yang, J | 1 |
| Niu, MM | 1 |
| Caimi, G | 1 |
| Urso, C | 1 |
| Brucculeri, S | 1 |
| Amato, C | 1 |
| Lo Presti, R | 1 |
| Carlisi, M | 1 |
| Shiina, K | 1 |
| Tomiyama, H | 2 |
| Tanaka, A | 4 |
| Yoshida, H | 3 |
| Eguchi, K | 2 |
| Kario, K | 2 |
| Kato, T | 3 |
| Teragawa, H | 3 |
| Toyoda, S | 3 |
| Ohishi, M | 2 |
| Fukumoto, Y | 1 |
| Takase, B | 1 |
| Ishizu, T | 3 |
| Node, K | 4 |
| Ma, M | 2 |
| Wang, L | 2 |
| Zhong, X | 2 |
| Zhong, L | 1 |
| Chen, R | 1 |
| Li, L | 2 |
| Mao, M | 2 |
| Hamasaki, S | 1 |
| Watarai, M | 1 |
| Ueda, S | 2 |
| Inoue, T | 1 |
| Hu, X | 1 |
| Liu, J | 2 |
| Li, W | 3 |
| Wang, C | 1 |
| Li, G | 1 |
| Zhou, Y | 2 |
| Dong, H | 1 |
| Gao, Y | 1 |
| Xu, B | 2 |
| Yang, Y | 2 |
| Zhang, M | 1 |
| Yu, T | 1 |
| Zhang, Q | 1 |
| Sun, J | 2 |
| Liu, R | 2 |
| Wang, Y | 2 |
| Ouyang, S | 1 |
| Li, M | 1 |
| Zhang, Y | 2 |
| Liu, X | 2 |
| Li, T | 1 |
| Liu, S | 1 |
| Fujii, Y | 1 |
| Ueda, T | 1 |
| Nomura, S | 1 |
| Kadokami, T | 1 |
| Koide, H | 1 |
| Saito, M | 1 |
| Sano, H | 1 |
| Bando, YK | 1 |
| Murohara, T | 2 |
| Taguchi, I | 1 |
| Ishizaka, N | 3 |
| Kanzaki, Y | 1 |
| Sata, M | 1 |
| Sezai, A | 1 |
| Ishibashi, R | 1 |
| Maemura, K | 1 |
| Higashi, Y | 1 |
| Yamada, H | 1 |
| Yokote, K | 1 |
| Oyama, JI | 1 |
| Tanaka, K | 1 |
| Kabayama, M | 1 |
| Sugimoto, K | 1 |
| Akasaka, H | 1 |
| Takami, Y | 1 |
| Takeya, Y | 1 |
| Yamamoto, K | 1 |
| Sekiguchi, T | 1 |
| Kiyoshige, E | 1 |
| Akagi, Y | 1 |
| Godai, K | 1 |
| Yasumoto, S | 1 |
| Masui, Y | 1 |
| Gondo, Y | 1 |
| Ikebe, K | 1 |
| Arai, Y | 1 |
| Ishizaki, T | 1 |
| Rakugi, H | 1 |
| Kamide, K | 1 |
| Huang, W | 1 |
| Wang, H | 1 |
| Peng, B | 1 |
| Zhang, H | 1 |
| Gao, Z | 1 |
| Lü, K | 1 |
| Song, C | 1 |
| Zhao, X | 2 |
| Maloberti, A | 1 |
| Maggioni, S | 1 |
| Occhi, L | 1 |
| Triglione, N | 1 |
| Panzeri, F | 1 |
| Nava, S | 1 |
| Signorini, S | 1 |
| Falbo, R | 1 |
| Casati, M | 1 |
| Grassi, G | 2 |
| Giannattasio, C | 1 |
| Feng, L | 1 |
| Hua, C | 1 |
| Sun, H | 1 |
| Qin, LY | 1 |
| Niu, PP | 1 |
| Guo, ZN | 1 |
| Lu, J | 2 |
| Sun, M | 1 |
| Wu, X | 1 |
| Yuan, X | 1 |
| Liu, Z | 1 |
| Qu, X | 1 |
| Ji, X | 1 |
| Merriman, TR | 1 |
| Li, C | 1 |
| Bombelli, M | 1 |
| Macchiarulo, M | 1 |
| Facchetti, R | 1 |
| Maggiolini, D | 1 |
| Cuspidi, C | 2 |
| Parati, G | 1 |
| Mancia, G | 2 |
| Weghuber, D | 1 |
| Zelzer, S | 1 |
| Stelzer, I | 1 |
| Paulmichl, K | 1 |
| Kammerhofer, D | 1 |
| Schnedl, W | 1 |
| Molnar, D | 1 |
| Mangge, H | 1 |
| Bae, JS | 1 |
| Shin, DH | 1 |
| Park, PS | 1 |
| Choi, BY | 1 |
| Kim, MK | 1 |
| Shin, MH | 1 |
| Lee, YH | 1 |
| Chun, BY | 1 |
| Kim, SK | 1 |
| Tan, C | 1 |
| Liu, Y | 1 |
| Deng, F | 1 |
| Wang, X | 1 |
| Gui, Y | 1 |
| Qin, L | 1 |
| Hu, C | 1 |
| Chen, L | 2 |
| Cicero, AF | 1 |
| Desideri, G | 1 |
| Grossi, G | 1 |
| Urso, R | 1 |
| Rosticci, M | 1 |
| D'Addato, S | 1 |
| Borghi, C | 1 |
| Mallamaci, F | 1 |
| Testa, A | 1 |
| Leonardis, D | 1 |
| Tripepi, R | 1 |
| Pisano, A | 1 |
| Spoto, B | 1 |
| Sanguedolce, MC | 1 |
| Parlongo, RM | 1 |
| Tripepi, G | 1 |
| Zoccali, C | 1 |
| Mayer, FJ | 1 |
| Mannhalter, C | 1 |
| Minar, E | 1 |
| Schillinger, M | 1 |
| Chavakis, T | 1 |
| Siegert, G | 1 |
| Arneth, BM | 1 |
| Koppensteiner, R | 1 |
| Hoke, M | 1 |
| Chen, Y | 3 |
| Sun, W | 1 |
| Wang, T | 1 |
| Xu, Y | 1 |
| Xu, M | 2 |
| Li, X | 1 |
| Bi, Y | 1 |
| Wang, W | 3 |
| Ning, G | 1 |
| Kawada, T | 1 |
| Andou, T | 1 |
| Fukumitsu, M | 1 |
| Li, LX | 1 |
| Wang, AP | 1 |
| Zhang, R | 1 |
| Li, TT | 1 |
| Wang, JW | 1 |
| Bao, YQ | 1 |
| Jia, WP | 1 |
| Li, Q | 2 |
| Dong, K | 1 |
| Wang, A | 1 |
| Yang, X | 1 |
| Zhang, C | 1 |
| Zhu, Y | 1 |
| Wu, S | 1 |
| Altun, B | 1 |
| Cintosun, U | 1 |
| Ozturk, K | 1 |
| Lee, JH | 1 |
| Kang, YS | 1 |
| Jeong, YJ | 1 |
| Yoon, YS | 1 |
| Kwack, WG | 1 |
| Oh, JY | 1 |
| Gagliardi, AC | 1 |
| Miname, MH | 1 |
| Santos, RD | 1 |
| Pacifico, L | 1 |
| Cantisani, V | 1 |
| Anania, C | 1 |
| Bonaiuto, E | 1 |
| Martino, F | 1 |
| Pascone, R | 1 |
| Chiesa, C | 1 |
| Neogi, T | 1 |
| Ellison, RC | 1 |
| Hunt, S | 1 |
| Terkeltaub, R | 1 |
| Felson, DT | 1 |
| Li, Y | 1 |
| Zhao, D | 1 |
| Li, ZA | 1 |
| Yong, Q | 1 |
| Yilmaz, MI | 1 |
| Qureshi, AR | 1 |
| Carrero, JJ | 1 |
| Saglam, M | 1 |
| Suliman, ME | 1 |
| Caglar, K | 1 |
| Eyileten, T | 1 |
| Sonmez, A | 1 |
| Oguz, Y | 1 |
| Vural, A | 1 |
| Yenicesu, M | 1 |
| Axelsson, J | 1 |
| Antonini-Canterin, F | 1 |
| La Carrubba, S | 1 |
| Gullace, G | 1 |
| Zito, C | 1 |
| Di Bello, V | 1 |
| Di Salvo, G | 1 |
| Benedetto, F | 1 |
| Novo, S | 1 |
| Pezzano, A | 1 |
| Perticone, F | 1 |
| Balbarini, A | 1 |
| Carerj, S | 1 |
| Yang, Z | 1 |
| Lu, B | 1 |
| Wen, J | 1 |
| Ye, Z | 1 |
| He, M | 1 |
| Tao, X | 1 |
| Zhang, W | 1 |
| Huang, Y | 1 |
| Zhang, Z | 1 |
| Qu, S | 1 |
| Hu, R | 1 |
| Takayama, S | 1 |
| Kawamoto, R | 4 |
| Kusunoki, T | 1 |
| Abe, M | 1 |
| Onji, M | 1 |
| Jiang, S | 1 |
| Sun, X | 1 |
| Gu, H | 1 |
| Xi, C | 1 |
| Qiao, X | 1 |
| Chen, X | 1 |
| Gür, M | 1 |
| Sahin, DY | 1 |
| Elbasan, Z | 1 |
| Kalkan, GY | 1 |
| Yıldız, A | 1 |
| Kaya, Z | 1 |
| Özaltun, B | 1 |
| Çaylı, M | 1 |
| Ishizaka, Y | 2 |
| Toda, E | 2 |
| Nagai, R | 2 |
| Yamakado, M | 2 |
| Viazzi, F | 1 |
| Parodi, D | 1 |
| Leoncini, G | 1 |
| Parodi, A | 1 |
| Falqui, V | 1 |
| Ratto, E | 1 |
| Vettoretti, S | 1 |
| Bezante, GP | 1 |
| Del Sette, M | 1 |
| Deferrari, G | 1 |
| Pontremoli, R | 1 |
| Tomita, H | 3 |
| Oka, Y | 3 |
| Kodama, A | 1 |
| Ohtsuka, N | 3 |
| Kamitani, A | 1 |
| Hashimoto, H | 1 |
| Tavil, Y | 1 |
| Kaya, MG | 1 |
| Oktar, SO | 1 |
| Sen, N | 1 |
| Okyay, K | 1 |
| Yazici, HU | 1 |
| Cengel, A | 1 |
| Valerio, C | 1 |
| Sala, C | 1 |
| Meani, S | 1 |
| Esposito, A | 1 |
| Zanchetti, A | 1 |
| Bächli, H | 1 |
| Langemann, H | 1 |
| Mendelowitsch, A | 1 |
| Alessandri, B | 1 |
| Landolt, H | 1 |
| Gratzl, O | 1 |
| Pan, WH | 1 |
| Bai, CH | 1 |
| Chen, JR | 1 |
| Chiu, HC | 1 |
| Saito, D | 1 |
| Shiraki, T | 1 |
| Oka, T | 1 |
| Kajiyama, A | 1 |
| Doi, M | 1 |
| Masaka, T | 1 |
| Nieto, FJ | 1 |
| Iribarren, C | 1 |
| Gross, MD | 1 |
| Comstock, GW | 1 |
| Cutler, RG | 1 |
| Patetsios, P | 1 |
| Song, M | 1 |
| Shutze, WP | 1 |
| Pappas, C | 1 |
| Rodino, W | 1 |
| Ramirez, JA | 1 |
| Panetta, TF | 1 |
| Gilroy, J | 1 |
| Sano, Y | 1 |
| Kanematsu, EH | 1 |
| Yoshiura, M | 1 |
| Iwamoto, T | 1 |
| Takizawa, N | 1 |
| Tokuhisa, T | 1 |
| Mizuno, A | 1 |
| Schneidau, A | 1 |
| Harrison, MJ | 1 |
| Hurst, C | 1 |
| Wilkes, HC | 1 |
| Meade, TW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study for the Investigation of New Individual Risk Profiles and Therapeutic Strategies in Obesity Related Cardiovascular and Metabolic Disorders.[NCT00482924] | 1,500 participants (Anticipated) | Observational | 2003-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for uric acid and Arterial Diseases, Carotid
| Article | Year |
|---|---|
Meta-analysis of the correlation between serum uric acid level and carotid intima-media thickness.
Topics: Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Carotid Stenosis; Humans; | 2021 |
Value and Progress of Ultrasound in Diagnosis and Treatment of Hyperuricemia.
Topics: Arthritis, Gouty; Carotid Artery Diseases; Gout; Humans; Hyperuricemia; Kidney; Non-alcoholic Fatty | 2017 |
Uric acid: A marker of increased cardiovascular risk.
Topics: Biomarkers; Cardiovascular Diseases; Carotid Artery Diseases; Coronary Artery Disease; Female; Heart | 2009 |
Early manifestations and investigation of cerebral arteriosclerosis.
Topics: Angiography; Basilar Artery; Blood Glucose; Brain; Carotid Artery Diseases; Cerebrovascular Disorder | 1976 |
8 trials available for uric acid and Arterial Diseases, Carotid
| Article | Year |
|---|---|
Differential effect of a xanthine oxidase inhibitor on arterial stiffness and carotid atherosclerosis: a subanalysis of the PRIZE study.
Topics: Ankle Brachial Index; Atherosclerosis; Awards and Prizes; Carotid Artery Diseases; Enzyme Inhibitors | 2022 |
Association between serum urate level and carotid atherosclerosis: an insight from a post hoc analysis of the PRIZE randomised clinical trial.
Topics: Adult; Awards and Prizes; Carotid Artery Diseases; Carotid Intima-Media Thickness; Febuxostat; Human | 2022 |
Effect of febuxostat on the level of malondialdehyde-modified low-density lipoprotein, an oxidative stress marker: A subanalysis of the PRIZE study.
Topics: Carotid Artery Diseases; Cholesterol, LDL; Febuxostat; Humans; Hyperuricemia; Malondialdehyde; Oxida | 2023 |
Febuxostat does not delay progression of carotid atherosclerosis in patients with asymptomatic hyperuricemia: A randomized, controlled trial.
Topics: Aged; Aged, 80 and over; Asymptomatic Diseases; Carotid Artery Diseases; Carotid Intima-Media Thickn | 2020 |
Serum uric acid and resistance to antihypertensive treatment: data from the European Lacidipine Study on Atherosclerosis.
Topics: Antihypertensive Agents; Atenolol; Atherosclerosis; Blood Pressure; Carotid Artery Diseases; Dihydro | 2019 |
High risk vs. "metabolically healthy" phenotype in juvenile obesity - neck subcutaneous adipose tissue and serum uric acid are clinically relevant.
Topics: Adiponectin; Adolescent; Carotid Artery Diseases; Child; Child, Preschool; Female; Humans; Insulin R | 2013 |
The Association between Serum Uric Acid Levels and the Prevalence of Vulnerable Atherosclerotic Carotid Plaque: A Cross-sectional Study.
Topics: Adult; Aged; Carotid Artery Diseases; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Pl | 2015 |
Lack of association between serum uric acid and organ damage in a never-treated essential hypertensive population at low prevalence of hyperuricemia.
Topics: Adult; Albuminuria; Carotid Artery Diseases; Female; Humans; Hypertension; Hypertrophy, Left Ventric | 2007 |
46 other studies available for uric acid and Arterial Diseases, Carotid
| Article | Year |
|---|---|
Association between serum uric acid and carotid atherosclerosis in elderly postmenopausal women: A hospital-based study.
Topics: Aged; Ambulatory Care; Carotid Artery Diseases; Female; Follow-Up Studies; Hormone Replacement Thera | 2022 |
Uric acid and uric acid/creatinine ratio and their correlations with the hemorheological determinants in subjects with subclinical carotid atherosclerosis.
Topics: Aged; Carotid Artery Diseases; Creatinine; Female; Humans; Hyperuricemia; Insulin Resistance; Male; | 2022 |
Age and Gender Differences Between Carotid Intima-Media Thickness and Serum Uric Acid.
Topics: Adult; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; F | 2022 |
Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis.
Topics: Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Carotid Stenosis; Choleste | 2022 |
Association Between Serum Uric Acid and Carotid Intima-Media Thickness in Different Fasting Blood Glucose Patterns: A Case-Control Study.
Topics: Blood Glucose; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Choles | 2022 |
Association Between Serum Uric Acid Level and Carotid Atherosclerosis and Metabolic Syndrome in Patients With Type 2 Diabetes Mellitus.
Topics: Carotid Artery Diseases; Carotid Intima-Media Thickness; Cross-Sectional Studies; Diabetes Mellitus, | 2022 |
Association between uric acid and atherosclerosis in community-dwelling older people: The SONIC study.
Topics: Aged; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cross-Sectional Stud | 2021 |
Serum 25-Hydroxyvitamin D3 Levels Are Associated with Carotid Intima-Media Thickness and Carotid Atherosclerotic Plaque in Type 2 Diabetic Patients.
Topics: Adult; Blood Glucose; Calcifediol; Calcium; Carotid Artery Diseases; Carotid Intima-Media Thickness; | 2017 |
Uric acid promotes oxidative stress and enhances vascular endothelial cell apoptosis in rats with middle cerebral artery occlusion.
Topics: Aged; Aged, 80 and over; Animals; Apoptosis; Carotid Artery Diseases; Cerebral Infarction; Endotheli | 2018 |
Sex-related relationships between uric acid and target organ damage in hypertension.
Topics: Adult; Aged; Carotid Artery Diseases; Carotid Intima-Media Thickness; Correlation of Data; Cross-Sec | 2018 |
Association between Serum Uric Acid Level and Carotid Atherosclerosis in Chinese Individuals Aged 75 Years or Older: A Hospital-Based Case-Control Study.
Topics: Aged, 80 and over; Asian People; Carotid Artery Diseases; Case-Control Studies; Female; Humans; Male | 2018 |
Urate-lowering therapy alleviates atherosclerosis inflammatory response factors and neointimal lesions in a mouse model of induced carotid atherosclerosis.
Topics: Allopurinol; Animals; Antimetabolites; Carotid Artery Diseases; Human Umbilical Vein Endothelial Cel | 2019 |
The impact of serum uric acid level on arterial stiffness and carotid atherosclerosis: the Korean Multi-Rural Communities Cohort study.
Topics: Adult; Aged; Ankle Brachial Index; Asian People; Carotid Arteries; Carotid Artery Diseases; Carotid | 2013 |
Associations of matrix metalloproteinase-9 and monocyte chemoattractant protein-1 concentrations with carotid atherosclerosis, based on measurements of plaque and intima-media thickness.
Topics: Adult; Aged; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Chemokine CC | 2014 |
Serum uric acid and impaired cognitive function in a cohort of healthy young elderly: data from the Brisighella Study.
Topics: Aged; Carotid Artery Diseases; Cognition; Cohort Studies; Female; Humans; Italy; Longitudinal Studie | 2015 |
A genetic marker of uric acid level, carotid atherosclerosis, and arterial stiffness: a family-based study.
Topics: Adult; Alleles; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cross-Sectional | 2015 |
The impact of uric acid on long-term mortality in patients with asymptomatic carotid atherosclerotic disease.
Topics: Aged; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Female; Humans; Male; Middle Aged; Progn | 2015 |
Impact of the Serum Uric Acid Level on Subclinical Atherosclerosis in Middle-aged and Elderly Chinese.
Topics: Adult; Age Factors; Aged; Asian People; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Caroti | 2015 |
Metabolic syndrome showed significant relationship with carotid atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Carotid Arteries; Carotid Artery Dis | 2016 |
Decreased urine uric acid excretion is an independent risk factor for chronic kidney disease but not for carotid atherosclerosis in hospital-based patients with type 2 diabetes: a cross-sectional study.
Topics: Adult; Aged; Biomarkers; Carotid Artery Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2 | 2015 |
Risk Factors for Subclinical Atherosclerosis and Uric Acid.
Topics: Asian People; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Female; Huma | 2015 |
Risk Factors for Subclinical Atherosclerosis and Uric Acid--Reply.
Topics: Asian People; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Female; Huma | 2015 |
Relationship between FEV1 and Cardiovascular Risk Factors in General Population without Airflow Limitation.
Topics: Adult; Age Factors; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Carotid Artery Dise | 2016 |
Serum uric acid and its association with metabolic syndrome and carotid atherosclerosis in obese children.
Topics: Alanine Transaminase; Blood Glucose; Blood Pressure; Carotid Artery Diseases; Child; Cholesterol; Co | 2009 |
Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study.
Topics: Adult; Aged; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Carotid Stenosis; Cohort Studies | 2009 |
[The association between hyperuricemia and prevalence of carotid plaque].
Topics: Aged; Carotid Artery Diseases; Cohort Studies; Female; Humans; Hyperuricemia; Male; Middle Aged; Pre | 2008 |
Predictors of carotid artery intima-media thickness in chronic kidney disease and kidney transplant patients without overt cardiovascular disease.
Topics: Adult; Biomarkers; Blood Pressure; Carotid Artery Diseases; Carotid Artery, Common; Cross-Sectional | 2010 |
Association between carotid atherosclerosis and metabolic syndrome: results from the ISMIR study.
Topics: Aged; Blood Glucose; Carotid Artery Diseases; Creatinine; Cross-Sectional Studies; Female; Fibrinoge | 2010 |
Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Carotid Steno | 2011 |
Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Asian People; Biomarkers; Carotid Artery Diseases; Caro | 2012 |
Age-related change in kidney function, its influencing factors, and association with asymptomatic carotid atherosclerosis in healthy individuals--a 5-year follow-up study.
Topics: Age Factors; Aged; Aging; Blood Pressure; Carotid Artery Diseases; China; Cholesterol, LDL; Cross-Se | 2012 |
Uric acid and high sensitive C-reactive protein are associated with subclinical thoracic aortic atherosclerosis.
Topics: Adult; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Biomarkers; C-Reactive Protein; Carotid Ar | 2013 |
Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Bilirubin; Carotid Artery Diseases; Cross-Sectional St | 2005 |
Serum uric acid and target organ damage in primary hypertension.
Topics: Adult; Albuminuria; Biomarkers; Carotid Artery Diseases; Female; Humans; Hypertension; Hypertrophy, | 2005 |
Association between uric acid and carotid atherosclerosis in elderly persons.
Topics: Aged; Aged, 80 and over; Carotid Artery Diseases; Cross-Sectional Studies; Female; Humans; Linear Mo | 2005 |
Association between risk factors and carotid enlargement.
Topics: Adaptation, Physiological; Aged; Alcohol Drinking; Body Mass Index; Cardiovascular Diseases; Carotid | 2006 |
Higher serum uric acid is associated with increased arterial stiffness in Japanese individuals.
Topics: Aged; Atherosclerosis; Brachial Artery; Carotid Arteries; Carotid Artery Diseases; Elasticity; Femal | 2007 |
Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis.
Topics: Aged; Aged, 80 and over; Carotid Artery Diseases; Carotid Artery, Common; Female; Humans; Incidence; | 2006 |
Uric acid level and its association with carotid intima-media thickness in patients with hypertension.
Topics: Adult; Carotid Artery Diseases; Carotid Artery, Common; Female; Humans; Hypertension; Hyperuricemia; | 2008 |
Microdialytic monitoring during cerebrovascular surgery.
Topics: Ascorbic Acid; Biomarkers; Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Cerebr | 1996 |
Associations between carotid atherosclerosis and high factor VIII activity, dyslipidemia, and hypertension.
Topics: Adult; Age Factors; Aged; Antithrombin III; Arteriosclerosis; Blood Pressure; Carotid Artery Disease | 1997 |
Morphologic correlation between atherosclerotic lesions of the carotid and coronary arteries in patients with angina pectoris.
Topics: Aged; Angina Pectoris; Arteriosclerosis; Blood Pressure; C-Reactive Protein; Carotid Artery Diseases | 1999 |
Uric acid and serum antioxidant capacity: a reaction to atherosclerosis?
Topics: Antioxidants; Arteriosclerosis; Bilirubin; Carotenoids; Carotid Artery Diseases; Case-Control Studie | 2000 |
Identification of uric acid and xanthine oxidase in atherosclerotic plaque.
Topics: Adult; Aged; Cadaver; Carotid Arteries; Carotid Artery Diseases; Case-Control Studies; Endarterectom | 2001 |
Uric acid as biochemical marker for retinal and optic nerve damage after occlusion and reperfusion of common carotid and vertebral arteries in rat.
Topics: Animals; Arterial Occlusive Diseases; Biomarkers; Carotid Artery Diseases; Chromatography, High Pres | 1992 |
Arterial disease risk factors and angiographic evidence of atheroma of the carotid artery.
Topics: Aging; Angiography, Digital Subtraction; Arteriosclerosis; Carotid Artery Diseases; Cerebrovascular | 1989 |