uric acid has been researched along with Arrhythmias, Cardiac in 37 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Elevated uric acid (UA) level is reported to be related to the development of left ventricular hypertrophy (LVH) which is associated with high incidence of ventricular tachycardia (VT) and sudden cardiac death." | 7.78 | Uric acid increases the incidence of ventricular arrhythmia in patients with left ventricular hypertrophy. ( Kamioka, M; Kamiyama, Y; Saitoh, S; Suzuki, H; Takeishi, Y; Yamada, S, 2012) |
| "Gout is a systemic disease, characterized by the formation and deposition of crystals in tissues (mainly in and around the joints) of individuals with elevated serum uric acid levels." | 5.01 | Gout and arrhythmias: In search for causation beyond association. ( Angelidis, C; Deftereos, S; Giannopoulos, G, 2019) |
| "Elevated uric acid (UA) level is reported to be related to the development of left ventricular hypertrophy (LVH) which is associated with high incidence of ventricular tachycardia (VT) and sudden cardiac death." | 3.78 | Uric acid increases the incidence of ventricular arrhythmia in patients with left ventricular hypertrophy. ( Kamioka, M; Kamiyama, Y; Saitoh, S; Suzuki, H; Takeishi, Y; Yamada, S, 2012) |
| " Severities of ischaemia (ST-segment elevation, inhomogeneity of electrical activation) and ventricular arrhythmias (VPBs, VT, VF), plasma nitrate/nitrite levels, as well as myocardial superoxide and nitrotyrosine productions were determined." | 3.77 | Is there a trigger role of peroxynitrite in the anti-arrhythmic effect of ischaemic preconditioning and peroxynitrite infusion? ( Juhász, L; Kaszaki, J; Kiss, A; Kovács, M; Nyeso, E; Seprényi, G; Végh, A, 2011) |
| "A 7-year followup study among men with hyperuricemia was conducted to study the longterm relationships between serum uric acid concentrations and cardiovascular diseases." | 3.72 | Hypertension was the major risk factor leading to development of cardiovascular diseases among men with hyperuricemia. ( Chen, CH; Chou, P; Lin, KC; Tsao, HM, 2004) |
| "Diuretics have long been used in the treatment of hypertension and are outstandingly efficacious when used either alone or in combination with other antihypertensive compounds." | 2.38 | Diuretics in hypertension: clinical experiences. ( Papademetriou, V, 1992) |
| "Febuxostat is a xanthine oxidase inhibitor used to reduce the formation of uric acid and prevent gout attacks." | 1.72 | Febuxostat Increases Ventricular Arrhythmogenesis Through Calcium Handling Dysregulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. ( Cai, C; Chen, M; Cui, C; Lin, Z; Liu, H; Qin, H; Zheng, B; Zhu, Y, 2022) |
| " Chronic use of XO inhibitors, but not uricosuric agent, down-regulated sympathetic innervation probably through a superoxide-dependent pathway and plays a role in the beneficial effect on arrhythmogenic response." | 1.43 | Effects of urate-lowering agents on arrhythmia vulnerability in post-infarcted rat hearts. ( Chang, NC; Lee, TM; Lin, SZ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (51.35) | 18.7374 |
| 1990's | 5 (13.51) | 18.2507 |
| 2000's | 5 (13.51) | 29.6817 |
| 2010's | 6 (16.22) | 24.3611 |
| 2020's | 2 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Dewi, IP | 1 |
| Putra, KNS | 1 |
| Dewi, KP | 1 |
| Wardhani, LFK | 1 |
| Julario, R | 1 |
| Dharmadjati, BB | 1 |
| Zhu, Y | 1 |
| Zheng, B | 1 |
| Cai, C | 1 |
| Lin, Z | 1 |
| Qin, H | 1 |
| Liu, H | 1 |
| Cui, C | 1 |
| Chen, M | 1 |
| Giannopoulos, G | 1 |
| Angelidis, C | 1 |
| Deftereos, S | 1 |
| Cicero, AF | 1 |
| Rosticci, M | 1 |
| Reggi, A | 1 |
| Derosa, G | 1 |
| Parini, A | 1 |
| Grandi, E | 1 |
| D'Addato, S | 1 |
| Borghi, C | 1 |
| Lee, TM | 1 |
| Lin, SZ | 1 |
| Chang, NC | 1 |
| Szymanowska, K | 1 |
| Piatkowska, A | 1 |
| Nowicka, A | 1 |
| Michalski, M | 1 |
| Dankowski, R | 1 |
| Kandziora, M | 1 |
| Biegalski, W | 1 |
| Wierzchowiecki, M | 1 |
| Poprawski, K | 1 |
| Lazzeri, C | 1 |
| Valente, S | 1 |
| Tarquini, R | 1 |
| Chiostri, M | 1 |
| Picariello, C | 1 |
| Gensini, GF | 1 |
| Juhász, L | 1 |
| Kiss, A | 1 |
| Nyeso, E | 1 |
| Kovács, M | 1 |
| Seprényi, G | 1 |
| Kaszaki, J | 1 |
| Végh, A | 1 |
| Yamada, S | 1 |
| Suzuki, H | 1 |
| Kamioka, M | 1 |
| Kamiyama, Y | 1 |
| Saitoh, S | 1 |
| Takeishi, Y | 1 |
| Lin, KC | 1 |
| Tsao, HM | 1 |
| Chen, CH | 1 |
| Chou, P | 1 |
| Gunnare, S | 1 |
| Ernstgård, L | 1 |
| Sjögren, B | 1 |
| Johanson, G | 1 |
| Ogilvie, RI | 1 |
| Wilcox, RG | 1 |
| Richardson, D | 1 |
| Hampton, JR | 1 |
| Mitchell, JR | 1 |
| Banks, DC | 1 |
| Cognazzo, A | 1 |
| Grasso, E | 1 |
| Gerbino Promis, PC | 1 |
| Zagnoni, P | 1 |
| De Bacquer, D | 1 |
| Martins Pereira, LS | 1 |
| De Backer, G | 1 |
| De Henauw, S | 1 |
| Kornitzer, M | 1 |
| Altug, S | 1 |
| Demiryürek, AT | 2 |
| Cakici, I | 1 |
| Kanzik, I | 1 |
| Altup, S | 1 |
| Ak, D | 1 |
| Tungel, M | 1 |
| Kanzik , I | 1 |
| Shehab, AM | 1 |
| Butler, R | 1 |
| MacFadyen, RJ | 1 |
| Struthers, AD | 1 |
| Mertz, DP | 1 |
| Rusteborg, J | 1 |
| Fevery, J | 1 |
| Persky, VW | 1 |
| Dyer, AR | 1 |
| Idris-Soven, E | 1 |
| Stamler, J | 1 |
| Shekelle, RB | 1 |
| Schoenberger, JA | 1 |
| Berkson, DM | 1 |
| Lindberg, HA | 1 |
| Papademetriou, V | 2 |
| Pella, J | 1 |
| Stancák, B | 1 |
| Bodnár, J | 1 |
| Sedlák, J | 1 |
| Schroner, Z | 1 |
| Lacoursiere, L | 1 |
| Kingma, JG | 1 |
| Moser, M | 4 |
| Black, H | 1 |
| Stair, D | 1 |
| McDonald, CJ | 1 |
| Hui, SL | 1 |
| Tierney, WM | 1 |
| Jelliffe, RW | 1 |
| Hill, D | 1 |
| Tatter, D | 1 |
| Lewis, E | 1 |
| Jahnecke, J | 1 |
| Ritter, M | 1 |
| Kreuzer, H | 1 |
| Kübler, W | 1 |
| Loogen, F | 1 |
| Ghani, MF | 1 |
| Parker, BM | 1 |
| Smith, JR | 1 |
| Kohn, RM | 1 |
| Ibrahim, MA | 1 |
| Feldman, JG | 1 |
| Varricchio, M | 1 |
| Tirri, G | 1 |
| Russo, R | 1 |
| Gentile, S | 1 |
| Barbeau, A | 1 |
| Mars, H | 1 |
| Gillo-Joffroy, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005140] | 0 participants | Observational | 1977-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for uric acid and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Serum uric acid and the risk of ventricular arrhythmias: a systematic review.
Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Humans; Risk Factors; Uric Acid | 2022 |
Gout and arrhythmias: In search for causation beyond association.
Topics: Ablation Techniques; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biomarkers; Gout; Gout Suppressan | 2019 |
[Biochemical basis of the effects of alcohol].
Topics: Acetaldehyde; Alcoholism; Arrhythmias, Cardiac; Carbohydrate Metabolism; Citrates; Citric Acid Cycle | 1976 |
Diuretics in hypertension: clinical experiences.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Hypokalemia; Risk F | 1992 |
The dilemma of mild hypertension.
Topics: Arrhythmias, Cardiac; Blood Glucose; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Hypo | 1986 |
The diuretic dilemma and the management of mild hypertension.
Topics: Arrhythmias, Cardiac; Blood Glucose; Cholesterol; Diuretics; Humans; Hypertension; Hypokalemia; Uric | 1986 |
The diuretic dilemma and the management of mild hypertension.
Topics: Arrhythmias, Cardiac; Decision Making; Diuretics; Drug Therapy, Combination; Glucose; Humans; Hypert | 1986 |
4 trials available for uric acid and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Sulphinpyrazone in acute myocardial infarction: studies on cardiac rhythm and renal function.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Creatinine; Double-Blind Method; Female; Humans; Mal | 1980 |
A placebo-controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure.
Topics: Aged; Allopurinol; Arrhythmias, Cardiac; Cardiac Output, Low; Cross-Over Studies; Data Interpretatio | 2001 |
In defense of traditional antihypertensive therapy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 1988 |
The dilemma of mild hypertension.
Topics: Arrhythmias, Cardiac; Blood Glucose; Clinical Trials as Topic; Diuretics; Humans; Hypertension; Hypo | 1986 |
27 other studies available for uric acid and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Febuxostat Increases Ventricular Arrhythmogenesis Through Calcium Handling Dysregulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Topics: Allopurinol; Arrhythmias, Cardiac; Calcium; Extracellular Signal-Regulated MAP Kinases; Febuxostat; | 2022 |
Relationship between serum uric acid and electrocardiographic alterations in a large sample of general population: data from the Brisighella Heart Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Biomarkers; Electrocardiography; F | 2015 |
Effects of urate-lowering agents on arrhythmia vulnerability in post-infarcted rat hearts.
Topics: Animals; Arrhythmias, Cardiac; Febuxostat; GAP-43 Protein; Male; Myocardial Infarction; Myocardium; | 2016 |
Clinical significance of heart rate turbulence assessment in patients with chronic heart failure.
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Case-Control Studies; Causality; Chronic Disea | 2008 |
Prognostic values of admission transaminases in ST-elevation myocardial infarction submitted to primary angioplasty.
Topics: Age Factors; Alanine Transaminase; Angioplasty; Arrhythmias, Cardiac; Aspartate Aminotransferases; D | 2010 |
Is there a trigger role of peroxynitrite in the anti-arrhythmic effect of ischaemic preconditioning and peroxynitrite infusion?
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Vessels | 2011 |
Uric acid increases the incidence of ventricular arrhythmia in patients with left ventricular hypertrophy.
Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Biomarkers; Female; Humans; Hypertrophy, Left Ventric | 2012 |
Hypertension was the major risk factor leading to development of cardiovascular diseases among men with hyperuricemia.
Topics: Adult; Arrhythmias, Cardiac; Arteriosclerosis; Female; Follow-Up Studies; Humans; Hypertension; Hype | 2004 |
Toxicokinetics of 1,1,1,2-tetrafluoroethane (HFC-134a) in male volunteers after experimental exposure.
Topics: Adult; Algorithms; Arrhythmias, Cardiac; C-Reactive Protein; Central Nervous System; Clinical Trials | 2006 |
Diuretic treatment in essential hypertension.
Topics: Aged; Arrhythmias, Cardiac; Blood Glucose; Diuretics; Dose-Response Relationship, Drug; Hemodynamics | 1983 |
[Frequency of risk factors in cerebrovascular disease and their effect on the course and outcome. Study on 423 hospitalized patients].
Topics: Aged; Aging; Arrhythmias, Cardiac; Cerebrovascular Disorders; Coronary Disease; Diabetes Complicatio | 1981 |
Prevalences and correlates of ECG abnormalities in the adult Belgian population.
Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Belgium; Blood Pressure; Body Mass Index; Calcium; D | 1995 |
The beneficial effects of peroxynitrite on ischaemia-reperfusion arrhythmias in rat isolated hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Catalase; Dose-Response Relationship, Drug; H | 1999 |
Contribution of peroxynitrite to the beneficial effects of preconditioning on ischaemia-induced arrhythmias in rat isolated hearts.
Topics: Animals; Arrhythmias, Cardiac; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfu | 2001 |
[Duplication of the left atrioventricular orifice (author's transl)].
Topics: Adult; Allopurinol; Arrhythmias, Cardiac; Blood Glucose; Cardiomegaly; Cholesterol; Diphosphates; El | 1975 |
Uric acid: a risk factor for coronary heart disease?
Topics: Arrhythmias, Cardiac; Chicago; Coronary Disease; Electrocardiography; Female; Heart Conduction Syste | 1979 |
[Uric acid and sinoatrial node function].
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Humans; Middle Aged; Retrospective Studies; Si | 1992 |
Reperfusion-induced arrhythmias are not prevented by uric acid in the isolated rat heart.
Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Free Radical Scavengers; In Vitro Techniques; Male; | 1991 |
Clinical significance of metabolic disturbances induced by the use of diuretics.
Topics: Arrhythmias, Cardiac; Blood Glucose; Cardiomegaly; Diuretics; Humans; Hyperkalemia; Lipids; Potassiu | 1987 |
Diuretic-induced laboratory abnormalities that predict ventricular ectopy.
Topics: Arrhythmias, Cardiac; Blood Chemical Analysis; Computers; Diuretics; Electrocardiography; Female; Fo | 1986 |
Death from weight-control pills. A case report with objective postmortem confirmation.
Topics: Adult; Amphetamine; Appetite Depressants; Arrhythmias, Cardiac; Death, Sudden; Digitalis Glycosides; | 1969 |
[Side effects of antihypertensive agents].
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Diarrhea; Diuretics; Fatigue; Ganglionic Blockers; Ga | 1970 |
[Frequency of ST-T segment changes on electrocardiograms in paients with mitral stenosis].
Topics: Adult; Age Factors; Aged; Antistreptolysin; Arrhythmia, Sinus; Arrhythmias, Cardiac; Blood Coagulati | 1974 |
Recognition of myocardial infarction after cardiac surgery and its relation to cardiopulmonary bypass.
Topics: Alanine Transaminase; Angiography; Arrhythmias, Cardiac; Aspartate Aminotransferases; Cardiac Cathet | 1974 |
Premature ventricular beats and coronary heart disease risk factors.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Cholesterol; Coronary Disease; Electrocardi | 1971 |
[Clinico-statistical studies on coronary insufficiency and heart rhythm changes in an aged patient with gout].
Topics: Adult; Aged; Arrhythmias, Cardiac; Arteriosclerosis; Coronary Disease; Gout; Humans; Middle Aged; Ur | 1971 |
Adverse clinical side effects of levodopa therapy.
Topics: Antiparkinson Agents; Arrhythmias, Cardiac; Benserazide; Carboxy-Lyases; Dihydroxyphenylalanine; Ede | 1971 |