Page last updated: 2024-10-20

uric acid and Apnea, Sleep

uric acid has been researched along with Apnea, Sleep in 17 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to determine whether the severity of sleep-disordered breathing (SDB) was associated with increased levels of uric acid (UA), both in serum and in urine, as a marker of tissue hypoxia, in a sample of overweight and obese subjects, irrespective of indexes of adiposity."9.12Sleep-disordered breathing and uric acid in overweight and obese children and adolescents. ( De Backer, WA; Desager, KN; Haentjens, D; Rooman, R; Schrauwen, N; Van Gaal, L; Van Hoeck, K; Verhulst, SL, 2007)
"Serum uric acid (UA) level is associated with the high cumulative incidence or prevalence of coronary artery disease (CAD), and hyperuricemia is considered as an independent risk marker for CAD."8.31Overnight changes in uric acid, xanthine oxidoreductase and oxidative stress levels and their relationships with sleep-disordered breathing in patients with coronary artery disease. ( Daida, H; Hiki, M; Ishiwata, S; Kasai, T; Kato, T; Kuwabara, M; Matsumoto, H; Murase, T; Murata, A; Naito, R; Nakamura, T; Sato, A; Shimizu, M; Shitara, J; Suda, S; Yatsu, S, 2023)
"In conclusion, weight loss is effective in treating obese children with SDB."5.38Weight loss and sleep-disordered breathing in childhood obesity: effects on inflammation and uric acid. ( Aerts, P; De Backer, WA; Debode, P; Desager, KN; Franckx, H; Ramet, J; Van Gaal, LF; Van Hoorenbeeck, K; Verhulst, SL; Wouters, K, 2012)
"The aim of this study was to determine whether the severity of sleep-disordered breathing (SDB) was associated with increased levels of uric acid (UA), both in serum and in urine, as a marker of tissue hypoxia, in a sample of overweight and obese subjects, irrespective of indexes of adiposity."5.12Sleep-disordered breathing and uric acid in overweight and obese children and adolescents. ( De Backer, WA; Desager, KN; Haentjens, D; Rooman, R; Schrauwen, N; Van Gaal, L; Van Hoeck, K; Verhulst, SL, 2007)
"Serum uric acid (UA) level is associated with the high cumulative incidence or prevalence of coronary artery disease (CAD), and hyperuricemia is considered as an independent risk marker for CAD."4.31Overnight changes in uric acid, xanthine oxidoreductase and oxidative stress levels and their relationships with sleep-disordered breathing in patients with coronary artery disease. ( Daida, H; Hiki, M; Ishiwata, S; Kasai, T; Kato, T; Kuwabara, M; Matsumoto, H; Murase, T; Murata, A; Naito, R; Nakamura, T; Sato, A; Shimizu, M; Shitara, J; Suda, S; Yatsu, S, 2023)
"To assess the utility of urinary uric acid excretion as a marker of nocturnal hypoxia in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after the institution of nasal continuous positive airway pressure (CPAP)."3.70Changes in urinary uric acid excretion in obstructive sleep apnea before and after therapy with nasal continuous positive airway pressure. ( Sahebjani, H, 1998)
"During hypoxia ATP degradation to uric acid is increased in animal models and humans."3.68Overnight urinary uric acid: creatinine ratio for detection of sleep hypoxemia. Validation study in chronic obstructive pulmonary disease and obstructive sleep apnea before and after treatment with nasal continuous positive airway pressure. ( Braghiroli, A; Donner, CF; Erbetta, M; Ruga, V; Sacco, C, 1993)
"It was concluded that the insomnia was more prevalent than the sleep apnea."1.72Epidemiological studies of sleep disorder in educational community of Pakistani population, its major risk factors and associated diseases. ( Ahmad, S; Akmal, H; Ashfaq, M; Aslam, MW; Ditta, A; Jafar, K; Javed, T; Khan, MS; Khan, T; Rehman, TU; Sehgal, SA; Tahir, R; Umar, A; Waheed, A; Wajid, M, 2022)
"In conclusion, weight loss is effective in treating obese children with SDB."1.38Weight loss and sleep-disordered breathing in childhood obesity: effects on inflammation and uric acid. ( Aerts, P; De Backer, WA; Debode, P; Desager, KN; Franckx, H; Ramet, J; Van Gaal, LF; Van Hoorenbeeck, K; Verhulst, SL; Wouters, K, 2012)
"Recurrent hypoxia associated with sleep apnea-hypopnea syndrome (SAHS) leads to an increase in the degradation of adenosine triphosphatase to xanthine and, secondarily, to an increase in uric acid concentrations."1.33[Blood uric acid levels in patients with sleep-disordered breathing]. ( Capote, F; Carmona Bernal, C; García Aguilar, D; Luque Crespo, E; Romero Falcón, A; Ruiz García, A; Sánchez Armengol, A, 2006)
"To determine if obstructive sleep apnea (OSA) is independently associated with cardiovascular risk factors and health status in subjects with severe obesity."1.29Impact of obstructive sleep apnea and sleepiness on metabolic and cardiovascular risk factors in the Swedish Obese Subjects (SOS) Study. ( Grunstein, RR; Hedner, J; Sjöström, L; Stenlöf, K, 1995)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's5 (29.41)29.6817
2010's2 (11.76)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Umar, A1
Khan, MS1
Sehgal, SA1
Jafar, K1
Ahmad, S1
Waheed, A1
Aslam, MW1
Wajid, M1
Rehman, TU1
Khan, T1
Ditta, A1
Akmal, H1
Ashfaq, M1
Javed, T1
Tahir, R1
Shimizu, M1
Kasai, T1
Naito, R1
Sato, A1
Ishiwata, S1
Yatsu, S1
Shitara, J1
Matsumoto, H1
Murata, A1
Kato, T1
Suda, S1
Hiki, M1
Kuwabara, M1
Murase, T1
Nakamura, T1
Daida, H1
Ando, SI1
Sunadome, H1
Murase, K1
Tabara, Y1
Matsumoto, T1
Minami, T1
Kanai, O1
Nagasaki, T1
Takahashi, N1
Hamada, S1
Tanizawa, K1
Togawa, J1
Uiji, S1
Wakamura, T1
Komenami, N1
Setoh, K1
Kawaguchi, T1
Morita, S1
Takahashi, Y1
Nakayama, T1
Hirai, T1
Sato, S1
Matsuda, F1
Chin, K1
Lai, CH1
Huang, RJ1
Wong, JK1
Chang, SW1
Chung, AH1
Chi, YC1
Yu, YC1
Lee, SD1
Ting, H1
Van Hoorenbeeck, K1
Franckx, H1
Debode, P1
Aerts, P1
Wouters, K1
Ramet, J1
Van Gaal, LF1
Desager, KN2
De Backer, WA2
Verhulst, SL2
Abrams, B1
Saito, H1
Nishimura, M1
Shibuya, E1
Makita, H1
Tsujino, I1
Miyamoto, K1
Kawakami, Y1
Matsumoto, Y1
Ruiz García, A1
Sánchez Armengol, A1
Luque Crespo, E1
García Aguilar, D1
Romero Falcón, A1
Carmona Bernal, C1
Capote, F1
Van Hoeck, K1
Schrauwen, N1
Haentjens, D1
Rooman, R1
Van Gaal, L1
Grunstein, RR1
Stenlöf, K1
Hedner, J1
Sjöström, L1
Braghiroli, A1
Sacco, C1
Erbetta, M1
Ruga, V1
Donner, CF1
Sahebjani, H1
Xiao, Y1
Yin, K1
Zheng, P1
Kubota, O1
Nishimura, K1
Inoue, Y1
Akutsu, H1
Mizuno, H1
McKeon, JL1
Saunders, NA1
Murree-Allen, K1
Olson, LG1
Gyulay, S1
Dickeson, J1
Houghton, A1
Wlodarczyk, J1
Hensley, MJ1

Reviews

1 review available for uric acid and Apnea, Sleep

ArticleYear
[Sleep apnea syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1

    Topics: Cardiovascular Diseases; Gout; Humans; Hyperuricemia; Life Style; Sleep Apnea Syndromes; Uric Acid

2003

Trials

1 trial available for uric acid and Apnea, Sleep

ArticleYear
Sleep-disordered breathing and uric acid in overweight and obese children and adolescents.
    Chest, 2007, Volume: 132, Issue:1

    Topics: Adiposity; Adolescent; Biomarkers; Child; Female; Humans; Hypoxia; Linear Models; Male; Obesity; Ove

2007

Other Studies

15 other studies available for uric acid and Apnea, Sleep

ArticleYear
Epidemiological studies of sleep disorder in educational community of Pakistani population, its major risk factors and associated diseases.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Adult; Epidemiologic Studies; Female; Headache; Humans; Male; Migraine Disorders; Pakistan; Prevalen

2022
Overnight changes in uric acid, xanthine oxidoreductase and oxidative stress levels and their relationships with sleep-disordered breathing in patients with coronary artery disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:10

    Topics: Coronary Artery Disease; Humans; Hyperuricemia; Male; Oxidative Stress; Sleep Apnea Syndromes; Uric

2023
Can we obtain a reliable marker that shows the hypoxic burden in patients with sleep disordered breathing?
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:11

    Topics: Coronary Artery Disease; Humans; Hypoxia; Sleep Apnea Syndromes; Uric Acid; Xanthine Dehydrogenase

2023
Associations between Sleep-Disordered Breathing and Serum Uric Acid and Their Sex Differences: The Nagahama Study.
    Nutrients, 2023, Sep-30, Volume: 15, Issue:19

    Topics: Diabetes Mellitus; Female; Humans; Male; Oxygen; Sex Characteristics; Sleep Apnea Syndromes; Uric Ac

2023
Confounded by obesity and modulated by urinary uric acid excretion, sleep-disordered breathing indirectly relates to hyperuricaemia in males: A structural equation model.
    Journal of sleep research, 2021, Volume: 30, Issue:3

    Topics: Biomarkers; Body Mass Index; Humans; Hyperuricemia; Male; Middle Aged; Obesity; Polysomnography; Sle

2021
Weight loss and sleep-disordered breathing in childhood obesity: effects on inflammation and uric acid.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:1

    Topics: Adenoidectomy; Adolescent; Belgium; Biomarkers; Child; Female; Follow-Up Studies; Humans; Inflammati

2012
High prevalence of gout with sleep apnea.
    Medical hypotheses, 2012, Volume: 78, Issue:2

    Topics: Glomerular Filtration Rate; Gout; Humans; Hypoxia; Prevalence; Sleep Apnea Syndromes; Uric Acid

2012
Tissue hypoxia in sleep apnea syndrome assessed by uric acid and adenosine.
    Chest, 2002, Volume: 122, Issue:5

    Topics: Adenosine; Adult; Biomarkers; Cell Hypoxia; Humans; Male; Middle Aged; Postpoliomyelitis Syndrome; S

2002
[Blood uric acid levels in patients with sleep-disordered breathing].
    Archivos de bronconeumologia, 2006, Volume: 42, Issue:10

    Topics: Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Retrospective Studies; Sleep Apnea Syndr

2006
Impact of obstructive sleep apnea and sleepiness on metabolic and cardiovascular risk factors in the Swedish Obese Subjects (SOS) Study.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1995, Volume: 19, Issue:6

    Topics: Adult; Anthropometry; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Female

1995
Overnight urinary uric acid: creatinine ratio for detection of sleep hypoxemia. Validation study in chronic obstructive pulmonary disease and obstructive sleep apnea before and after treatment with nasal continuous positive airway pressure.
    The American review of respiratory disease, 1993, Volume: 148, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Circadian Rhythm; Creatinine; Female; Humans; Hypoxia; Lung Disea

1993
Changes in urinary uric acid excretion in obstructive sleep apnea before and after therapy with nasal continuous positive airway pressure.
    Chest, 1998, Volume: 113, Issue:6

    Topics: Creatinine; Humans; Hypoxia; Male; Middle Aged; Positive-Pressure Respiration; Prospective Studies;

1998
[Significance of the changes of urinary uric acid, ANP, renin and aldosterone in sleep apnea syndrome patients].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2000, Volume: 23, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Creatinine; Female; Humans; Male; Middle Aged; Renin;

2000
[The metabolic index of nocturnal hypoxia in patients after lung resection and thoracoplasty].
    Nihon Kyobu Shikkan Gakkai zasshi, 1991, Volume: 29, Issue:7

    Topics: Aged; Coenzymes; Creatinine; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pneumonectomy

1991
Urinary uric acid:creatinine ratio, serum erythropoietin, and blood 2,3-diphosphoglycerate in patients with obstructive sleep apnea.
    The American review of respiratory disease, 1990, Volume: 142, Issue:1

    Topics: 2,3-Diphosphoglycerate; Circadian Rhythm; Creatinine; Diphosphoglyceric Acids; Erythropoietin; Femal

1990