uric acid has been researched along with Anoxia-Ischemia, Brain in 7 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previously, we developed a pharmacokinetic-pharmacodynamic model of allopurinol, oxypurinol, and biomarkers, hypoxanthine, xanthine, and uric acid, in neonates with hypoxic-ischemic encephalopathy, in which high initial biomarker levels were observed suggesting an impact of hypoxia." | 4.12 | Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates. ( Allegaert, K; Chu, WY; Dorlo, TPC; Huitema, ADR, 2022) |
| " The key findings leading to diagnosis were neonatal seizures unresponsive to treatment, craniofacial dysmorphic features, hyperexcitability, low blood uric acid levels, and neuroimaging findings." | 3.71 | Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy. ( Coskun, T; Haliloglu, G; Saatci, I; Topcu, M, 2001) |
| " The dosage used and the effect of allopurinol in this population, either or not undergoing therapeutic hypothermia (TH), were evaluated." | 3.11 | Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates. ( Allegaert, K; Annink, KV; Bakkali, LE; Benders, MJNL; Chu, WY; Dorlo, TPC; Franz, AR; Hagen, A; Huitema, ADR; Maiwald, CA; Nijstad, AL; Schroth, M; van Bel, F; van Weissenbruch, MM, 2022) |
| "To determine the incidence of acute renal failure (ARF) and nephrosonographic findings among asphyxiated neonates, and to correlate this with uric acid levels and the severity of hypoxic encephalopathy, we studied 80 full-term appropriate-for-date singleton neonates with perinatal asphyxia, and 30 healthy full-term neonates as controls from March 2006 to February 2007." | 1.37 | Acute renal failure: nephrosonographic findings in asphyxiated neonates. ( Ahmed, N; Chowdhary, J; Saif, RU, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, WY | 2 |
| Annink, KV | 1 |
| Nijstad, AL | 1 |
| Maiwald, CA | 1 |
| Schroth, M | 1 |
| Bakkali, LE | 1 |
| van Bel, F | 1 |
| Benders, MJNL | 1 |
| van Weissenbruch, MM | 1 |
| Hagen, A | 1 |
| Franz, AR | 1 |
| Dorlo, TPC | 2 |
| Allegaert, K | 2 |
| Huitema, ADR | 2 |
| Martini, S | 1 |
| Austin, T | 1 |
| Aceti, A | 1 |
| Faldella, G | 1 |
| Corvaglia, L | 1 |
| Bellos, I | 1 |
| Fitrou, G | 1 |
| Pergialiotis, V | 1 |
| Perrea, DN | 1 |
| Papantoniou, N | 1 |
| Daskalakis, G | 1 |
| Basu, P | 1 |
| Som, S | 1 |
| Choudhuri, N | 1 |
| Das, H | 1 |
| Ahmed, N | 1 |
| Chowdhary, J | 1 |
| Saif, RU | 1 |
| Topcu, M | 1 |
| Coskun, T | 1 |
| Haliloglu, G | 1 |
| Saatci, I | 1 |
2 reviews available for uric acid and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Asphyxia Neonatorum; Biomarkers; Brain Injuries; | 2020 |
Random urine uric acid to creatinine and prediction of perinatal asphyxia: a meta-analysis.
Topics: Apgar Score; Asphyxia Neonatorum; Biomarkers; Creatinine; Female; Humans; Hypoxia-Ischemia, Brain; I | 2019 |
1 trial available for uric acid and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.
Topics: Allopurinol; Biomarkers; Enzyme Inhibitors; Humans; Hypoxanthine; Hypoxia-Ischemia, Brain; Infant, N | 2022 |
4 other studies available for uric acid and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates.
Topics: Allopurinol; Clinical Studies as Topic; Humans; Hypoxanthine; Hypoxia; Hypoxia-Ischemia, Brain; Infa | 2022 |
Contribution of the blood glucose level in perinatal asphyxia.
Topics: Apgar Score; Asphyxia Neonatorum; Female; Glucose; Hospitals; Humans; Hypoxia-Ischemia, Brain; Infan | 2009 |
Acute renal failure: nephrosonographic findings in asphyxiated neonates.
Topics: Acute Kidney Injury; Asphyxia Neonatorum; Comorbidity; Creatinine; Humans; Hypoxia-Ischemia, Brain; | 2011 |
Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy.
Topics: Coenzymes; Diagnosis, Differential; Female; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn | 2001 |