Page last updated: 2024-10-20

uric acid and Angiitis

uric acid has been researched along with Angiitis in 9 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"High serum uric acid (SUA) levels are present in patients with metabolic syndrome (MetS), when the latter is associated with endothelial dysfunction, inflammation, and hypertension."3.81Association of serum uric acid levels to inflammation biomarkers and endothelial dysfunction in obese prepubertal children. ( Bermudo, F; Cañete, MD; Cañete, R; Martos, R; Valle, M; Valle, R; van Donkelaar, EL, 2015)
" The relationship between calcium oxalate (COX) crystals - implicated in the vasculitis of primary oxalosis - and immunologically mediated endothelial injury was also explored."3.66Mechanisms of vascular damage in gout and oxalosis: crystal induced, granulocyte mediated, endothelial injury. ( Boogaerts, MA; Hammerschmidt, DE; Jacob, HS; Roelant, C; Verwilghen, RL, 1983)
"Uric acid (UA) has been found to stimulate macrophage migration inhibitory factor (MIF) up-regulation in renal tubules from rats subjected to UA-induced nephropathy."1.51Blockage of macrophage migration inhibitory factor (MIF) suppressed uric acid-induced vascular inflammation, smooth muscle cell de-differentiation, and remodeling. ( Fu, X; Li, G; Liu, Q; Lou, Y; Mei, J; Niu, N; Qu, P; Sui, Z; Sun, J; Xu, M, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Drosos, GC1
Vedder, D1
Houben, E1
Boekel, L1
Atzeni, F1
Badreh, S1
Boumpas, DT1
Brodin, N1
Bruce, IN1
González-Gay, MÁ1
Jacobsen, S1
Kerekes, G1
Marchiori, F1
Mukhtyar, C1
Ramos-Casals, M1
Sattar, N1
Schreiber, K1
Sciascia, S1
Svenungsson, E1
Szekanecz, Z1
Tausche, AK1
Tyndall, A1
van Halm, V1
Voskuyl, A1
Macfarlane, GJ1
Ward, MM1
Nurmohamed, MT1
Tektonidou, MG1
Sessa, C1
Granata, A1
Gaudio, A1
Xourafa, A1
Malatino, L1
Lentini, P1
Fatuzzo, P1
Rapisarda, F1
Castellino, P1
Zanoli, L1
Fu, X1
Niu, N1
Li, G1
Xu, M1
Lou, Y1
Mei, J1
Liu, Q1
Sui, Z1
Sun, J1
Qu, P1
Valle, M1
Martos, R1
Cañete, MD1
Valle, R1
van Donkelaar, EL1
Bermudo, F1
Cañete, R1
Rajtar, R1
Kloch, M1
Bober, M1
Kolasińska-Kloch, W1
Boogaerts, MA1
Hammerschmidt, DE1
Roelant, C1
Verwilghen, RL1
Jacob, HS1
Zhioua, R1
Sebaï, L1
Kriaa, L1
el Euch, M1
Mabrouk, S1
Ouertani, A1
Meneshian, A1
Bulkley, GB1
Coutellier, P1
Delgrange, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Paediatric Obesity and Cardiovascular Dysfunction: Searching for Early Markers of Damage[NCT03169257]100 participants (Actual)Interventional2015-01-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for uric acid and Angiitis

ArticleYear
[Vascular dysfunction in Cardiorenal Syndrome type 4].
    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2020, Feb-12, Volume: 37, Issue:1

    Topics: Aorta; Arginine; Autonomic Nervous System Diseases; Bone Diseases, Metabolic; Cardio-Renal Syndrome;

2020
[The current opinion on inflammatory, biochemistry and hemostatic markers and factors in atherosclerosis. Part II].
    Przeglad lekarski, 2006, Volume: 63, Issue:9

    Topics: Animals; Atherosclerosis; Biomarkers; Causality; Clinical Trials as Topic; Comorbidity; Fibrin Fibri

2006
The physiology of endothelial xanthine oxidase: from urate catabolism to reperfusion injury to inflammatory signal transduction.
    Microcirculation (New York, N.Y. : 1994), 2002, Volume: 9, Issue:3

    Topics: Animals; Endothelium, Vascular; Humans; Reperfusion Injury; Signal Transduction; Uric Acid; Vasculit

2002

Other Studies

6 other studies available for uric acid and Angiitis

ArticleYear
EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome.
    Annals of the rheumatic diseases, 2022, Volume: 81, Issue:6

    Topics: Antiphospholipid Syndrome; Cardiovascular Diseases; Gout; Heart Disease Risk Factors; Humans; Lupus

2022
Blockage of macrophage migration inhibitory factor (MIF) suppressed uric acid-induced vascular inflammation, smooth muscle cell de-differentiation, and remodeling.
    Biochemical and biophysical research communications, 2019, 01-08, Volume: 508, Issue:2

    Topics: Animals; Cell Dedifferentiation; Cells, Cultured; Disease Models, Animal; Gene Knockdown Techniques;

2019
Association of serum uric acid levels to inflammation biomarkers and endothelial dysfunction in obese prepubertal children.
    Pediatric diabetes, 2015, Volume: 16, Issue:6

    Topics: Biomarkers; Body Mass Index; C-Reactive Protein; Child; Cross-Sectional Studies; Endothelium, Vascul

2015
Mechanisms of vascular damage in gout and oxalosis: crystal induced, granulocyte mediated, endothelial injury.
    Thrombosis and haemostasis, 1983, Aug-30, Volume: 50, Issue:2

    Topics: Blood Physiological Phenomena; Blood Platelets; Calcium Oxalate; Cell Adhesion; Cell Aggregation; Co

1983
[Risk factors and etiology of retinal vein occlusion].
    La Tunisie medicale, 1995, Volume: 73, Issue:2

    Topics: Adult; Age Factors; Aged; Arteriosclerosis; Behcet Syndrome; Coronary Disease; Diabetes Complication

1995
[Fatal toxic epidermolysis following administration of allopurinol].
    Acta clinica Belgica, 1989, Volume: 44, Issue:3

    Topics: Aged; Allopurinol; Epidermolysis Bullosa; Gastrointestinal Hemorrhage; Humans; Kidney Failure, Chron

1989