uric acid has been researched along with Anemia, Cooley's in 14 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mild adverse events were reported in 48 (9%) patients and serious adverse events, including cerebral vascular accident and portal vein thrombosis were reported in two patients each." | 3.30 | Long-term clinical efficacy and safety of thalidomide in patients with transfusion-dependent β-thalassemia: results from Thal-Thalido study. ( Ali, M; Ali, Z; Ismail, M; Khan, MTM; Rani, GF; Rehman, IU, 2023) |
| "The majority of patients with thalassemia major were males." | 1.46 | Kidney Function in Patients With Different Variants of Beta-Thalassemia. ( Ansari, S; Nickavar, A; Qmarsi, A; Zarei, E, 2017) |
| "Although all types of beta thalassemia patients should be closely monitored to prevent further decrease in renal functions, the patients with TI should be considered to have a higher risk of glomerular and tubular deterioration as well as TM." | 1.42 | Glomerular and tubular functions in children with different forms of beta thalassemia. ( Akdağ, B; Aral, YZ; Aybek, H; Balcı, YI; Uzun, E; Yüksel, S, 2015) |
| "However, patients with elevated phosphaturia, elevated uricuria and/or abnormal levels of calcaemia show a significant decline in eGFR over time, suggesting that tubular damage acquired in childhood caused by either TM or its treatment may eventually result in abnormal eGFR." | 1.38 | Renal function in patients with β-thalassaemia major: a long-term follow-up study. ( Carta, MP; Corrias, C; Lai, ME; Ponticelli, C; Spiga, A; Vacquer, S, 2012) |
| "Persons with beta-thalassemia minor usually are symptomless." | 1.32 | Renal tubular dysfunction in beta-thalassemia minor. ( Bulucu, F; Cetin, T; Kocar, IH; Kurt, I; Musabak, U; Oguz, Y; Oktenli, C; Ozgurtas, T; Sanisoglu, SY; Yenicesu, M; Yildiz, O, 2003) |
| "A study on thalassemia intermedia and major patients in Jakarta was initiated to obtain a comprehensive picture of metabolic dysregulation, iron overload, oxidative stress, and cell damage." | 1.32 | Iron status and oxidative stress in beta-thalassemia patients in Jakarta. ( Adhiyanto, C; Dillon, HS; Freisleben, HJ; Handayani, S; Hidayat, J; Kurniati, V; Kusnandar, S; Laksmitawati, DR; Munthe, BG; Ramelan, W; Soegianto, RR; Udyaningsih-Freisleben, SK; Wirawan, R, 2003) |
| "In patients with beta-thalassemia major, the most important cause of mortality and morbidity is organ failure due to deposits of iron." | 1.31 | Renal function in pediatric patients with beta-thalassemia major. ( Aldudak, B; Anarat, A; Anarat, R; Dikmen, N; Gali, E; Karabay Bayazit, A; Kilinç, Y; Noyan, A; Ozel, A; Sasmaz, I, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, Z | 1 |
| Ismail, M | 1 |
| Rehman, IU | 1 |
| Rani, GF | 1 |
| Ali, M | 1 |
| Khan, MTM | 1 |
| Ricchi, P | 1 |
| Meloni, A | 2 |
| Pistoia, L | 2 |
| Spasiano, A | 2 |
| Rita Gamberini, M | 1 |
| Maggio, A | 1 |
| Gerardi, C | 2 |
| Messina, G | 1 |
| Campisi, S | 1 |
| Allò, M | 1 |
| Renne, S | 1 |
| Righi, R | 2 |
| Midiri, M | 1 |
| Positano, V | 2 |
| Filosa, A | 2 |
| Pepe, A | 2 |
| Vassalle, C | 1 |
| Gamberini, MR | 1 |
| Zuccarelli, A | 1 |
| Casini, T | 1 |
| Missere, M | 1 |
| Ndreu, R | 1 |
| Chaloemwong, J | 1 |
| Tantiworawit, A | 1 |
| Rattanathammethee, T | 1 |
| Chai-Adisaksopha, C | 1 |
| Rattarittamrong, E | 1 |
| Norasetthada, L | 1 |
| Charoenkwan, P | 1 |
| Louthrenoo, W | 1 |
| Dasgupta, S | 1 |
| Dasgupta, A | 1 |
| Mukhopadhayay, T | 1 |
| Bhattacharya, S | 1 |
| Swaika, B | 1 |
| Banarjee, U | 1 |
| Chakrabarty, P | 1 |
| Uzun, E | 1 |
| Balcı, YI | 1 |
| Yüksel, S | 1 |
| Aral, YZ | 1 |
| Aybek, H | 1 |
| Akdağ, B | 1 |
| Nickavar, A | 1 |
| Qmarsi, A | 1 |
| Ansari, S | 1 |
| Zarei, E | 1 |
| Sadeghi-Bojd, S | 1 |
| Hashemi, M | 1 |
| Naderi, M | 1 |
| Shikhani, S | 1 |
| Ahmadzadeh, A | 1 |
| Jalali, A | 1 |
| Assar, S | 1 |
| Khalilian, H | 1 |
| Zandian, K | 1 |
| Pedram, M | 1 |
| Lai, ME | 1 |
| Spiga, A | 1 |
| Vacquer, S | 1 |
| Carta, MP | 1 |
| Corrias, C | 1 |
| Ponticelli, C | 1 |
| Cetin, T | 1 |
| Oktenli, C | 1 |
| Ozgurtas, T | 1 |
| Yenicesu, M | 1 |
| Sanisoglu, SY | 1 |
| Oguz, Y | 1 |
| Yildiz, O | 1 |
| Kurt, I | 1 |
| Musabak, U | 1 |
| Bulucu, F | 1 |
| Kocar, IH | 1 |
| Laksmitawati, DR | 1 |
| Handayani, S | 1 |
| Udyaningsih-Freisleben, SK | 1 |
| Kurniati, V | 1 |
| Adhiyanto, C | 1 |
| Hidayat, J | 1 |
| Kusnandar, S | 1 |
| Dillon, HS | 1 |
| Munthe, BG | 1 |
| Wirawan, R | 1 |
| Soegianto, RR | 1 |
| Ramelan, W | 1 |
| Freisleben, HJ | 1 |
| De Luca, C | 1 |
| Grandinetti, M | 1 |
| Maggio, F | 1 |
| Lamba, M | 1 |
| Passi, S | 1 |
| Aldudak, B | 1 |
| Karabay Bayazit, A | 1 |
| Noyan, A | 1 |
| Ozel, A | 1 |
| Anarat, A | 1 |
| Sasmaz, I | 1 |
| Kilinç, Y | 1 |
| Gali, E | 1 |
| Anarat, R | 1 |
| Dikmen, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cystatin C and Beta 2 Microglobulin as Biochemical Markers for Early Detection of Renal Impairment in Children With Beta Thalassemia[NCT03881917] | 150 participants (Anticipated) | Observational | 2019-11-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for uric acid and Anemia, Cooley's
| Article | Year |
|---|---|
Long-term clinical efficacy and safety of thalidomide in patients with transfusion-dependent β-thalassemia: results from Thal-Thalido study.
Topics: beta-Thalassemia; Ferritins; Humans; Hydroxyurea; Thalidomide; Treatment Outcome; Uric Acid | 2023 |
Hyperuricemia, urine uric excretion, and associated complications in thalassemia patients.
Topics: Adolescent; Adult; Arthritis, Gouty; beta-Thalassemia; Cross-Sectional Studies; Female; Glomerular F | 2019 |
12 other studies available for uric acid and Anemia, Cooley's
| Article | Year |
|---|---|
Longitudinal follow-up of patients with thalassaemia intermedia who started transfusion therapy in adulthood: a cohort study.
Topics: Adolescent; Adult; Aged; beta-Thalassemia; Bilirubin; Blood Platelets; Blood Transfusion; Bone Disea | 2020 |
Relationship between uric acid levels and cardiometabolic findings in a large cohort of β-thalassemia major patients.
Topics: Adult; beta-Thalassemia; Cohort Studies; Female; Ferritins; Humans; Iron; Liver; Magnetic Resonance | 2018 |
Serum uric acid: an early indicator of oxidative stress in beta thalassemia population.
Topics: Adolescent; Adult; Bangladesh; beta-Thalassemia; Case-Control Studies; Female; Ferritins; Humans; Ir | 2013 |
Glomerular and tubular functions in children with different forms of beta thalassemia.
Topics: Adolescent; alpha-Macroglobulins; beta 2-Microglobulin; beta-Thalassemia; Case-Control Studies; Chil | 2015 |
Kidney Function in Patients With Different Variants of Beta-Thalassemia.
Topics: Adolescent; Adult; beta-Thalassemia; Child; Creatinine; Cross-Sectional Studies; Female; Glomerular | 2017 |
Kidney function tests in children with beta-thalassemia minor in Zahedan, southeast of Iran.
Topics: Adolescent; beta 2-Microglobulin; beta-Thalassemia; Biomarkers; Child; Child, Preschool; Creatinine; | 2011 |
Renal tubular dysfunction in pediatric patients with beta-thalassemia major.
Topics: Acetylglucosaminidase; Adolescent; beta-Thalassemia; Child; Cross-Sectional Studies; Female; Ferriti | 2011 |
Renal function in patients with β-thalassaemia major: a long-term follow-up study.
Topics: Adult; beta-Thalassemia; Calcium; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hyp | 2012 |
Renal tubular dysfunction in beta-thalassemia minor.
Topics: Adult; beta 2-Microglobulin; beta-Thalassemia; Bone Diseases, Metabolic; Female; Hemoglobins; Humans | 2003 |
Iron status and oxidative stress in beta-thalassemia patients in Jakarta.
Topics: Adolescent; Adult; Antioxidants; beta-Thalassemia; Bilirubin; Blood Proteins; Child; Hemoglobins; Hu | 2003 |
Blood antioxidant status and urinary levels of catecholamine metabolites in beta-thalassemia.
Topics: Adolescent; Adult; Antioxidants; beta-Thalassemia; Bilirubin; Carotenoids; Catecholamines; Child; Fa | 1999 |
Renal function in pediatric patients with beta-thalassemia major.
Topics: Acetylglucosaminidase; Adolescent; Adult; beta-Thalassemia; Blood Urea Nitrogen; Child; Child, Presc | 2000 |