uric acid has been researched along with Amentia in 32 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the association between uric acid (UA) levels and vascular dementia (VaD) and Parkinson's disease dementia (PDD), a meta-analysis was conducted." | 9.41 | Uric acid levels and their association with vascular dementia and Parkinson's disease dementia: a meta-analysis. ( Cen, K; Cui, Y; Feng, X; Hou, X; Li, Q, 2023) |
| "Serum uric acid (sUA) level may be associated with cognitive impairment/dementia." | 8.93 | Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. ( Dawson, J; Fan, Y; Hewitt, J; Khan, AA; Quinn, TJ, 2016) |
| "Elevated serum uric acid (SUA) is associated with cardiovascular risk factors, which often contribute to dementia and dementia-like morbidity, yet several cross-sectional studies have shown protective associations with cognition, which would be consistent with other work showing benefits of elevated SUA through its antioxidant properties." | 7.96 | Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort. ( Alam, AB; Alonso, A; Power, MC; West, NA; Wu, A, 2020) |
| "In patients with gout, maintaining too low serum uric acid (SUA) level with urate-lowering therapy is a concern because uric acid is thought to be neuroprotective." | 7.88 | Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study. ( Bardin, T; Debette, S; Latourte, A; Perez-Ruiz, F; Richette, P; Soumaré, A, 2018) |
| "This narrative review aims to highlight recent findings on the relation between uric acid level and cognitive decline or dementia." | 7.88 | Uric acid and cognitive decline: a double-edge sword? ( Bardin, T; Latourte, A; Richette, P, 2018) |
| "To explore the association between uric acid (UA) levels and vascular dementia (VaD) and Parkinson's disease dementia (PDD), a meta-analysis was conducted." | 5.41 | Uric acid levels and their association with vascular dementia and Parkinson's disease dementia: a meta-analysis. ( Cen, K; Cui, Y; Feng, X; Hou, X; Li, Q, 2023) |
| "Uric acid is a risk factor of cardiovascular disease, as well as a major natural antioxidant, prohibiting the occurrence of cellular damage." | 5.35 | Serum uric acid and cognitive function and dementia. ( Breteler, MM; Euser, SM; Hofman, A; Westendorp, RG, 2009) |
| "This study conducts a systematic literature review and meta-analysis regarding the potential influence of serum uric acid levels on cerebral small vessel diseases and the cognitive status in the prodromal stages of dementia." | 5.22 | The relationship between uric acid and brain health from observational studies. ( Cardoso, MA; Simó, R; Song, ZH; Tang, X; Zhou, JB, 2022) |
| "Serum uric acid (sUA) level may be associated with cognitive impairment/dementia." | 4.93 | Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis. ( Dawson, J; Fan, Y; Hewitt, J; Khan, AA; Quinn, TJ, 2016) |
| "Elevated serum uric acid (SUA) is associated with cardiovascular risk factors, which often contribute to dementia and dementia-like morbidity, yet several cross-sectional studies have shown protective associations with cognition, which would be consistent with other work showing benefits of elevated SUA through its antioxidant properties." | 3.96 | Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort. ( Alam, AB; Alonso, A; Power, MC; West, NA; Wu, A, 2020) |
| "In patients with gout, maintaining too low serum uric acid (SUA) level with urate-lowering therapy is a concern because uric acid is thought to be neuroprotective." | 3.88 | Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study. ( Bardin, T; Debette, S; Latourte, A; Perez-Ruiz, F; Richette, P; Soumaré, A, 2018) |
| "This narrative review aims to highlight recent findings on the relation between uric acid level and cognitive decline or dementia." | 3.88 | Uric acid and cognitive decline: a double-edge sword? ( Bardin, T; Latourte, A; Richette, P, 2018) |
| "There is evidence that uric acid may have antioxidant and neuroprotective effects and might therefore alter the risk for neurodegenerative diseases such as dementia." | 3.88 | Hyperuricemia and dementia - a case-control study. ( Broich, K; Engel, B; Gomm, W; Haenisch, B; Maier, W; Weckbecker, K, 2018) |
| "Uric acid (UA) may not only prevent development of cognitive dysfunction owing to its antioxidant efficacy, but also may worsen cognitive functions by gaining pro-oxidant character." | 3.85 | Uric acid may be protective against cognitive impairment in older adults, but only in those without cardiovascular risk factors. ( Isik, AT; Kaya, D; Soysal, P; Tuven, B; Unutmaz, G, 2017) |
| "Concentrations of hypoxanthine, xanthine, uric acid and creatinine were measured in CSF of patients suffering form presenile and senile dementia of Alzheimer type (PDAT, SDAT) and multi infarct dementia (MID) and in a reference group of young neurotic patients." | 3.67 | Purine metabolites in the CSF in presenile and senile dementia of Alzheimer type, and in multi infarct dementia. ( Degrell, I; Niklasson, F, 1988) |
| "It is known that hyperuricemia is recognized as an independent cardiovascular risk factor." | 2.82 | [The role of hyperuricemia in the development of cognitive changes in the elderly.] ( Ariev, AL; Kunitskaya, NA, 2022) |
| "Hyperuricemia has been recognized as an independent cardiovascular risk factor in epidemiological studies." | 2.58 | Uric Acid and Cognitive Function in Older Individuals. ( Meschi, T; Nouvenne, A; Prati, B; Tana, C; Ticinesi, A, 2018) |
| "Both BMI and urate are independent predictors of dementia, and there are inverse monotonic and dose-response associations of BMI and urate with dementia." | 1.56 | Associations of BMI and Serum Urate with Developing Dementia: A Prospective Cohort Study. ( Cao, Z; Li, S; Wang, Y; Xu, C; Xu, F; Yang, H; Zhang, Y, 2020) |
| "Uric acid is a risk factor of cardiovascular disease, as well as a major natural antioxidant, prohibiting the occurrence of cellular damage." | 1.35 | Serum uric acid and cognitive function and dementia. ( Breteler, MM; Euser, SM; Hofman, A; Westendorp, RG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 13 (40.63) | 24.3611 |
| 2020's | 7 (21.88) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, X | 1 |
| Song, ZH | 1 |
| Cardoso, MA | 1 |
| Zhou, JB | 1 |
| Simó, R | 1 |
| Kunitskaya, NA | 1 |
| Ariev, AL | 1 |
| Li, Q | 1 |
| Cen, K | 1 |
| Cui, Y | 1 |
| Feng, X | 1 |
| Hou, X | 1 |
| Kawada, T | 1 |
| Alam, AB | 1 |
| Wu, A | 1 |
| Power, MC | 1 |
| West, NA | 1 |
| Alonso, A | 1 |
| Cao, Z | 1 |
| Xu, C | 1 |
| Yang, H | 1 |
| Li, S | 1 |
| Xu, F | 1 |
| Zhang, Y | 1 |
| Wang, Y | 1 |
| Mikhailichenko, N | 1 |
| Wang, YH | 1 |
| Wei, JC | 1 |
| Lai, TJ | 1 |
| Latourte, A | 3 |
| Soumaré, A | 2 |
| Bardin, T | 3 |
| Perez-Ruiz, F | 1 |
| Debette, S | 2 |
| Richette, P | 3 |
| Singh, JA | 2 |
| Lee, YH | 2 |
| Song, GG | 2 |
| Cleveland, J | 1 |
| Tana, C | 1 |
| Ticinesi, A | 1 |
| Prati, B | 1 |
| Nouvenne, A | 1 |
| Meschi, T | 1 |
| Engel, B | 1 |
| Gomm, W | 1 |
| Broich, K | 1 |
| Maier, W | 1 |
| Weckbecker, K | 1 |
| Haenisch, B | 1 |
| González-Aramburu, I | 1 |
| Sánchez-Juan, P | 1 |
| Sierra, M | 1 |
| Fernández-Juan, E | 1 |
| Sánchez-Quintana, C | 1 |
| Berciano, J | 1 |
| Combarros, O | 1 |
| Infante, J | 1 |
| Khan, AA | 1 |
| Quinn, TJ | 1 |
| Hewitt, J | 1 |
| Fan, Y | 1 |
| Dawson, J | 1 |
| Desideri, G | 1 |
| Gentile, R | 1 |
| Antonosante, A | 1 |
| Benedetti, E | 1 |
| Grassi, D | 1 |
| Cristiano, L | 1 |
| Manocchio, A | 1 |
| Selli, S | 1 |
| Ippoliti, R | 1 |
| Ferri, C | 1 |
| Borghi, C | 1 |
| Giordano, A | 1 |
| Cimini, A | 1 |
| Tuven, B | 1 |
| Soysal, P | 1 |
| Unutmaz, G | 1 |
| Kaya, D | 1 |
| Isik, AT | 1 |
| Euser, SM | 1 |
| Hofman, A | 1 |
| Westendorp, RG | 1 |
| Breteler, MM | 1 |
| Irizarry, MC | 1 |
| Raman, R | 1 |
| Schwarzschild, MA | 1 |
| Becerra, LM | 1 |
| Thomas, RG | 1 |
| Peterson, RC | 1 |
| Ascherio, A | 1 |
| Aisen, PS | 1 |
| Ruggiero, C | 1 |
| Cherubini, A | 1 |
| Lauretani, F | 1 |
| Bandinelli, S | 1 |
| Maggio, M | 1 |
| Di Iorio, A | 1 |
| Zuliani, G | 1 |
| Dragonas, C | 1 |
| Senin, U | 1 |
| Ferrucci, L | 1 |
| Aspray, TJ | 1 |
| Nesbit, K | 1 |
| Cassidy, TP | 1 |
| Farrow, E | 1 |
| Hawthorne, G | 1 |
| Reyes, AJ | 1 |
| Wikkelsø, C | 1 |
| Blomstrand, C | 1 |
| Nordquist, P | 1 |
| Degrell, I | 3 |
| Nagy, E | 1 |
| Kasa, M | 1 |
| Bierma, TJ | 1 |
| Waterstraat, F | 1 |
| Corsaut, M | 1 |
| Singh, SP | 1 |
| Niklasson, F | 2 |
| Hetta, J | 1 |
| March, J | 1 |
| Field, J | 1 |
| Shanley, J | 1 |
| Turner, WJ | 1 |
| Munch-Petersen, S | 1 |
| Pakkenberg, H | 1 |
| Kornerup, H | 1 |
| Ortmann, J | 1 |
| Ipsen, E | 1 |
| Jacobsen, P | 1 |
| Simmelsgård, H | 1 |
5 reviews available for uric acid and Amentia
| Article | Year |
|---|---|
The relationship between uric acid and brain health from observational studies.
Topics: Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Hum | 2022 |
[The role of hyperuricemia in the development of cognitive changes in the elderly.]
Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Dementia; Dementia, Vascular; Humans; Hyp | 2022 |
Uric acid levels and their association with vascular dementia and Parkinson's disease dementia: a meta-analysis.
Topics: Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Parkinson Disease; Reproducibility of Resul | 2023 |
Uric Acid and Cognitive Function in Older Individuals.
Topics: Aged; Alzheimer Disease; Cognition; Cognitive Dysfunction; Dementia; Dementia, Vascular; Disease Pro | 2018 |
Serum uric acid level and association with cognitive impairment and dementia: systematic review and meta-analysis.
Topics: Aging; Cognition; Cognitive Dysfunction; Dementia; Disease Progression; Humans; Neuropsychological T | 2016 |
2 trials available for uric acid and Amentia
| Article | Year |
|---|---|
Biochemical observations during a trial of inosiplex in senile dementia.
Topics: Aged; Amino Alcohols; Benzoates; Body Weight; Clinical Trials as Topic; Dementia; Humans; Hypoxanthi | 1973 |
RNA treatment of dementia. A double-blind study.
Topics: Aged; Animals; Autoradiography; Cholesterol; Clinical Trials as Topic; Creatinine; Dementia; Electro | 1974 |
25 other studies available for uric acid and Amentia
| Article | Year |
|---|---|
Serum uric acid and dementia subtype.
Topics: Cognitive Dysfunction; Dementia; Humans; Uric Acid | 2023 |
Associations of serum uric acid with incident dementia and cognitive decline in the ARIC-NCS cohort.
Topics: Aged; Atherosclerosis; Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Humans; Middle Aged | 2020 |
Associations of BMI and Serum Urate with Developing Dementia: A Prospective Cohort Study.
Topics: Adult; Aged; Body Mass Index; Cohort Studies; Dementia; Disease Progression; Female; Follow-Up Studi | 2020 |
Association between Anti-inflammatory Drug and Dementia in Patients with Gout: A Nationwide, Population-Based Nested Case-Control Study.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Case-Control Studies; Dementia; Female; Glucocorticoi | 2021 |
Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study.
Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Brain; Cohort Studies; Dementia; Female; Follow-Up Studi | 2018 |
Role of serum urate in neurocognitive function and dementia: new evidence contradicts old thinking.
Topics: Cohort Studies; Dementia; Gout; Humans; Research Design; Uric Acid | 2018 |
Uric acid and incident dementia: a population-based cohort study.
Topics: Cohort Studies; Dementia; Humans; Risk Factors; Uric Acid | 2018 |
Use of urate-lowering therapies is not associated with an increased risk of incident dementia in older adults.
Topics: Aged; Dementia; Gout; Humans; Uric Acid | 2018 |
Response to: 'Uric acid and incident dementia: a population-based cohort study' by Lee and Song.
Topics: Cohort Studies; Dementia; Gout; Humans; Research Design; Uric Acid | 2018 |
Response to: 'Use of urate-lowering therapies is not associated with an increase in the risk of incident dementia in older adults' by Lee and Song.
Topics: Aged; Dementia; Gout; Humans; Hyperuricemia; Uric Acid | 2018 |
Uric acid and cognitive decline: a double-edge sword?
Topics: Cognitive Dysfunction; Cross-Sectional Studies; Dementia; Gout; Humans; Hyperuricemia; Oxidative Str | 2018 |
Hyperuricemia and dementia - a case-control study.
Topics: Aged; Case-Control Studies; Dementia; Female; Gout; Humans; Hyperuricemia; Male; Middle Aged; Odds R | 2018 |
Serum uric acid and risk of dementia in Parkinson's disease.
Topics: Aged; Dementia; DNA Mutational Analysis; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; | 2014 |
Uric Acid Amplifies Aβ Amyloid Effects Involved in the Cognitive Dysfunction/Dementia: Evidences From an Experimental Model In Vitro.
Topics: Aldehydes; Amyloid; Amyloid beta-Peptides; Blotting, Western; Brain-Derived Neurotrophic Factor; Cel | 2017 |
Uric acid may be protective against cognitive impairment in older adults, but only in those without cardiovascular risk factors.
Topics: Aged; Aged, 80 and over; Cognitive Dysfunction; Dementia; Female; Heart Failure; Humans; Hypertensio | 2017 |
Serum uric acid and cognitive function and dementia.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Cognition Disorders; Dementia; Female; Follow-Up Studies; | 2009 |
Plasma urate and progression of mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Boston; Cognition Disorders; Confounding Factors, Epidem | 2009 |
Uric acid and dementia in community-dwelling older persons.
Topics: Aged; Alcohol Drinking; C-Reactive Protein; Cholesterol; Dementia; Energy Intake; Female; Humans; In | 2009 |
Diabetes in British nursing and residential homes: a pragmatic screening study.
Topics: Aged; Blood Glucose; Dementia; Diabetes Mellitus; Female; Glucose Tolerance Test; Homes for the Aged | 2006 |
Heart failure, dementia, and diuretics: is uric acid involved?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antihypertensive Agents; Cohort Studies; Dementia; Femal | 2006 |
Cerebrospinal fluid investigations in multi-infarct dementia and senile dementia.
Topics: Aged; Blood Proteins; Cerebrospinal Fluid Proteins; Dementia; Electrophoresis, Agar Gel; Humans; Hyd | 1981 |
Concentration gradients for HVA, 5-HIAA, ascorbic acid, and uric acid in cerebrospinal fluid.
Topics: Adult; Aged; Alcohol Amnestic Disorder; Ascorbic Acid; Brain; Dementia; Female; Homovanillic Acid; H | 1990 |
Routine blood chemistry screen: a diagnostic aid for Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Chemical Analysis; Dementia; Discriminant Analysis | 1989 |
Hypoxanthine, xanthine, urate and creatinine concentration gradients in cerebrospinal fluid.
Topics: Biological Transport, Active; Cisterna Magna; Creatinine; Dementia; Depression; Humans; Hypoxanthine | 1988 |
Purine metabolites in the CSF in presenile and senile dementia of Alzheimer type, and in multi infarct dementia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Creatinine; Dementia; Humans; Hypoxan | 1988 |