uric acid has been researched along with Alloxan Diabetes in 83 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thus, this study investigated whether the XOR inhibitor, topiroxostat, affected body weight." | 8.02 | Influence of xanthine oxidoreductase inhibitor, topiroxostat, on body weight of diabetic obese mice. ( Akari, S; Katoh, N; Mizukami, H; Murase, T; Nakamura, T; Nampei, M; Satoh, E, 2021) |
| "Uric acid has been proposed as an independent risk factor of diabetic retinopathy." | 7.88 | The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway. ( She, XP; Wang, YZ; Zheng, Z; Zhu, DD; Zou, C, 2018) |
| " Thus, this study investigated whether the XOR inhibitor, topiroxostat, affected body weight." | 4.02 | Influence of xanthine oxidoreductase inhibitor, topiroxostat, on body weight of diabetic obese mice. ( Akari, S; Katoh, N; Mizukami, H; Murase, T; Nakamura, T; Nampei, M; Satoh, E, 2021) |
| "The urate oxidase (Uox) gene encodes uricase that in the rodent liver degrades uric acid into allantoin, forming an obstacle for establishing stable mouse models of hyperuricemia." | 3.88 | Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders. ( Cheng, X; Cui, L; Hou, X; Jia, Z; Li, C; Li, X; Liu, Z; Lu, J; Ma, L; Mi, QS; Ren, W; Sun, R; Tian, Z; Wang, C; Wang, X; Xin, Y; Yuan, X; Zhang, K, 2018) |
| "Uric acid has been proposed as an independent risk factor of diabetic retinopathy." | 3.88 | The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway. ( She, XP; Wang, YZ; Zheng, Z; Zhu, DD; Zou, C, 2018) |
| " In STZ-diabetic group, blood glucose, serum sialic and uric acid levels, serum catalase (CAT) and lactate dehydrogenase (LDH) activities, brain lipid peroxidation (LPO) and nonenzymatic glycosylation (NEG) increased, while brain glutathione (GSH) level and body weight decreased." | 3.73 | Vanadyl sulfate administration protects the streptozotocin-induced oxidative damage to brain tissue in rats. ( Tunali, S; Yanardag, R, 2006) |
| " The diabetic dams presented hyperglycemia, hyperlipemia, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, decreased reduced glutathione (GSH), hepatic glycogen and superoxide dismutase (SOD) determinations." | 3.71 | Oxidative stress and diabetes in pregnant rats. ( Cunha Rudge, MV; Damasceno, DC; de Mattos Paranhos Calderon, I; Volpato, GT, 2002) |
| "As pioglitazone is an insulin sens MSDC-itizer used for diabetes, its MPC inhibitory effect in diabetic individuals was investigated." | 1.91 | Inactivation of mitochondrial pyruvate carrier promotes NLRP3 inflammasome activation and gout development via metabolic reprogramming. ( Chen, CC; Chen, LC; Chen, YJ; Chien, WC; Chung, CH; Huang, CN; Huang, KY; Liao, NS; Lin, HA; Lin, HC; Lin, YY; Ojcius, DM; Shih, CT; Tsai, KJ; Wang, JY, 2023) |
| "Collectively, Gln attenuates diabetic nephropathy and other complications in type 2 diabetes mellitus in rats through its antioxidant and anti-inflammatory activities." | 1.91 | Exogenous glutamine ameliorates diabetic nephropathy in a rat model of type 2 diabetes mellitus through its antioxidant and anti-inflammatory activities. ( Adibhesami, G; Ahmadvand, H; Babaeenezhad, E; Mahdavifard, S; Nasri, M, 2023) |
| "Hydralazine is an antihypertensive agent and may act as a xanthine oxidase (XO) inhibitor to reduce uric acid levels in a mouse renal injury model." | 1.72 | Antioxidation and Nrf2-mediated heme oxygenase-1 activation contribute to renal protective effects of hydralazine in diabetic nephropathy. ( Chang, TT; Chen, C; Chen, JW; Chiang, CH; Lee, HJ; Lin, SC, 2022) |
| "Diabetic nephropathy is reported to occur as a result of the interactions between several pathophysiological disturbances, as well as renal oxidative stress and inflammation." | 1.62 | Malaysian Propolis and Metformin Synergistically Mitigate Kidney Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats. ( Abu Bakar, AB; Jalil, NAC; Mohamed, M; Nna, VU; Othman, ZA; Zakaria, Z, 2021) |
| "Type 2 diabetes was induced by dietary manipulation for 56 days via (high fat- high fructose diet) and intraperitoneal administration of streptozocin (30 mg/kg)." | 1.51 | The freeze-dried extracts of Rotheca myricoides (Hochst.) Steane & Mabb possess hypoglycemic, hypolipidemic and hypoinsulinemic on type 2 diabetes rat model. ( Chege, BM; Frederick, B; Nyaga, NM; Waweru, MP, 2019) |
| "Therefore, Sar can markedly ameliorate diabetic nephropathy in rats via inhibition of NLRP3 inflammasome activation and AGEs-RAGE interaction." | 1.48 | Protective effects of sarsasapogenin against early stage of diabetic nephropathy in rats. ( Chen, YJ; Hao, YC; Kong, L; Liu, YW; Wang, TY; Yin, SY; Zhang, MY, 2018) |
| "Type 2 diabetes was induced in three groups using high-fat diet combined with a single dose of streptozotocin (35mg/kg body weight, intraperitoneally)." | 1.46 | Pancreatic and renal function in streptozotocin-induced type 2 diabetic rats administered combined inositol hexakisphosphate and inositol supplement. ( Alexander-Lindo, RL; Dilworth, LL; Foster, SR; Omoruyi, FO; Thompson, R, 2017) |
| "Heavy metals are known to be toxic to organisms." | 1.43 | Nephrotoxic effects of lead nitrate exposure in diabetic and nondiabetic rats: Involvement of oxidative stress and the protective role of sodium selenite. ( Baş, H; Kalender, Y, 2016) |
| "Experimental diabetes mellitus was produced by a single intraperitoneal injection of STZ (55mg/kg b." | 1.43 | Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats. ( Berredjem, H; Berredjem, M; Bouzerna, N; Cheloufi, H; Réggami, Y, 2016) |
| " B06-treated groups were given B06 by gavage at a dosage of 0." | 1.42 | [Protective effect of curcumin derivative B06 on kidney of type 2 diabetic rats]. ( Chen, GR; Chen, SM; Cheng, JG; Liu, WW; Liu, X; Wang, L; Zeng, CC, 2015) |
| "Mangiferin was orally treated with the dose of 40 mg/kg body weight/day for 30 days to diabetic rats." | 1.40 | Beneficial effects of mangiferin isolated from Salacia chinensis on biochemical and hematological parameters in rats with streptozotocin-induced diabetes. ( Arulselvan, P; Fakurazi, S; Kandasamy, M; Sellamuthu, PS, 2014) |
| "Diabetic nephropathy is the kidney disease that occurs as a result of diabetes." | 1.40 | Protective effect of bioflavonoid myricetin enhances carbohydrate metabolic enzymes and insulin signaling molecules in streptozotocin-cadmium induced diabetic nephrotoxic rats. ( Ashokkumar, N; Kandasamy, N, 2014) |
| "Eighteen rats with diabetic nephropathy and 6 rats without induced nephropathy were divided into 4 groups, each containing 6 animals." | 1.39 | Effect of silymarin on streptozotocin-nicotinamide-induced type 2 diabetic nephropathy in rats. ( Jose, MA; Kumar, BN; Sathyamurthy, D; Sheela, N, 2013) |
| " Acute toxicity and dosage fixation studies revealed that the Zn-flavonol complex is non toxic and oral administration of the complex at a concentration of 5mg/kg b." | 1.38 | Design, synthesis and characterization of zinc-3 hydroxy flavone, a novel zinc metallo complex for the treatment of experimental diabetes in rats. ( Iyyam Pillai, S; Subramanian, SP; Vijayaraghavan, K, 2012) |
| "Theophylline was metabolized to 1,3-DMU by CYP1A2 and 2E1 in rats." | 1.33 | Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1,3-dimethyluric acid formation. ( Kim, SG; Kim, SH; Kim, YC; Lee, AK; Lee, DC; Lee, I; Lee, JH; Lee, MG, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (14.46) | 18.7374 |
| 1990's | 4 (4.82) | 18.2507 |
| 2000's | 17 (20.48) | 29.6817 |
| 2010's | 39 (46.99) | 24.3611 |
| 2020's | 11 (13.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TT | 1 |
| Chiang, CH | 1 |
| Chen, C | 1 |
| Lin, SC | 1 |
| Lee, HJ | 2 |
| Chen, JW | 1 |
| Gomes, MA | 1 |
| Manzano, C | 1 |
| Alves, TM | 1 |
| Fiais, GA | 1 |
| Freitas, RN | 1 |
| Coutinho Mattera, MSL | 1 |
| Dornelles, RCM | 1 |
| Matsushita, DH | 1 |
| Stevanato Nakamune, ACM | 1 |
| Chaves-Neto, AH | 1 |
| Mbiakop, UC | 1 |
| Gomes, JHS | 1 |
| Pádua, RM | 1 |
| Lemos, VS | 1 |
| Braga, FC | 1 |
| Cortes, SF | 1 |
| Chen, LC | 1 |
| Chen, YJ | 2 |
| Lin, HA | 1 |
| Chien, WC | 1 |
| Tsai, KJ | 1 |
| Chung, CH | 1 |
| Wang, JY | 1 |
| Chen, CC | 1 |
| Liao, NS | 1 |
| Shih, CT | 1 |
| Lin, YY | 1 |
| Huang, CN | 1 |
| Ojcius, DM | 1 |
| Huang, KY | 1 |
| Lin, HC | 1 |
| Wang, YL | 1 |
| Lin, SX | 1 |
| Wang, Y | 4 |
| Liang, T | 1 |
| Jiang, T | 1 |
| Liu, P | 1 |
| Li, XY | 2 |
| Lang, DQ | 1 |
| Liu, Q | 4 |
| Shen, CY | 1 |
| Rehman, HU | 1 |
| Ullah, K | 1 |
| Rasool, A | 1 |
| Manzoor, R | 1 |
| Yuan, Y | 1 |
| Tareen, AM | 1 |
| Kaleem, I | 1 |
| Riaz, N | 1 |
| Hameed, S | 1 |
| Bashir, S | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 2 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 11 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 2 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 2 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 3 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 4 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 8 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 3 |
| Yan, Z | 3 |
| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 4 |
| Ren, Y | 1 |
| Li, J | 8 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 4 |
| Zhou, X | 2 |
| Wang, W | 3 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 2 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 6 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 2 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 3 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 2 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
| Bi, Z | 1 |
| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
| Richter, C | 1 |
| Edelhäuser, BAH | 1 |
| Engelmann, D | 1 |
| Brenmoehl, J | 1 |
| Söhnchen, C | 1 |
| Murr, N | 1 |
| Alpers, M | 1 |
| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
| Liao, Y | 1 |
| Cheng, J | 1 |
| Kong, X | 1 |
| Li, S | 1 |
| Zhang, M | 4 |
| Zhang, H | 1 |
| Yang, T | 2 |
| Dong, Y | 1 |
| Xu, Y | 1 |
| Yuan, Z | 1 |
| Cao, J | 1 |
| Zheng, Y | 2 |
| Luo, Z | 1 |
| Mei, Z | 1 |
| Yao, Y | 1 |
| Liu, Z | 4 |
| Liang, C | 1 |
| Yang, H | 1 |
| Song, Y | 1 |
| Yu, K | 1 |
| Zhu, C | 1 |
| Huang, Z | 1 |
| Qian, J | 1 |
| Ge, J | 1 |
| Hu, J | 2 |
| Wang, H | 3 |
| Liu, Y | 5 |
| Mi, Y | 1 |
| Kong, H | 1 |
| Xi, D | 1 |
| Yan, W | 1 |
| Luo, X | 1 |
| Ning, Q | 1 |
| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
| Reddy, K | 1 |
| Chen, H | 1 |
| Shin, SH | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Mu, W | 1 |
| Liu, C | 3 |
| Gao, F | 1 |
| Qi, Y | 1 |
| Lu, H | 1 |
| Zhang, X | 4 |
| Cai, X | 1 |
| Ji, RY | 1 |
| Hou, Y | 3 |
| Tian, J | 2 |
| Shi, Y | 3 |
| Ying, S | 1 |
| Tan, M | 1 |
| Feng, G | 1 |
| Kuang, Y | 1 |
| Chen, D | 1 |
| Wu, D | 3 |
| Zhu, ZQ | 1 |
| Tang, HX | 1 |
| Shi, ZE | 1 |
| Kang, J | 1 |
| Qi, J | 2 |
| Mu, J | 1 |
| Cong, Z | 1 |
| Chen, S | 2 |
| Fu, D | 1 |
| Li, Z | 3 |
| Celestrin, CP | 1 |
| Rocha, GZ | 1 |
| Stein, AM | 1 |
| Guadagnini, D | 1 |
| Tadelle, RM | 1 |
| Saad, MJA | 1 |
| Oliveira, AG | 1 |
| Bianconi, V | 1 |
| Bronzo, P | 1 |
| Banach, M | 1 |
| Sahebkar, A | 1 |
| Mannarino, MR | 1 |
| Pirro, M | 1 |
| Patsourakos, NG | 1 |
| Kouvari, M | 1 |
| Kotidis, A | 1 |
| Kalantzi, KI | 1 |
| Tsoumani, ME | 1 |
| Anastasiadis, F | 1 |
| Andronikos, P | 1 |
| Aslanidou, T | 1 |
| Efraimidis, P | 1 |
| Georgiopoulos, A | 1 |
| Gerakiou, K | 1 |
| Grigoriadou-Skouta, E | 1 |
| Grigoropoulos, P | 1 |
| Hatzopoulos, D | 1 |
| Kartalis, A | 1 |
| Lyras, A | 1 |
| Markatos, G | 1 |
| Mikrogeorgiou, A | 1 |
| Myroforou, I | 1 |
| Orkopoulos, A | 1 |
| Pavlidis, P | 1 |
| Petras, C | 1 |
| Riga, M | 1 |
| Skouloudi, M | 1 |
| Smyrnioudis, N | 1 |
| Thomaidis, K | 1 |
| Tsikouri, GE | 1 |
| Tsikouris, EI | 1 |
| Zisimos, K | 1 |
| Vavoulis, P | 1 |
| Vitali, MG | 1 |
| Vitsas, G | 1 |
| Vogiatzidis, C | 1 |
| Chantanis, S | 1 |
| Fousas, S | 1 |
| Panagiotakos, DB | 1 |
| Tselepis, AD | 1 |
| Jungen, C | 1 |
| Alken, FA | 1 |
| Eickholt, C | 1 |
| Scherschel, K | 1 |
| Kuklik, P | 1 |
| Klatt, N | 1 |
| Schwarzl, J | 1 |
| Moser, J | 1 |
| Jularic, M | 1 |
| Akbulak, RO | 1 |
| Schaeffer, B | 1 |
| Willems, S | 1 |
| Meyer, C | 1 |
| Nowak, JK | 1 |
| Szczepanik, M | 1 |
| Trypuć, M | 1 |
| Pogorzelski, A | 1 |
| Bobkowski, W | 1 |
| Grytczuk, M | 1 |
| Minarowska, A | 1 |
| Wójciak, R | 1 |
| Walkowiak, J | 1 |
| Lu, Y | 1 |
| Xi, J | 1 |
| Li, C | 2 |
| Chen, W | 2 |
| Hu, X | 1 |
| Zhang, F | 1 |
| Wei, H | 1 |
| Wang, Z | 1 |
| Gurzu, S | 1 |
| Jung, I | 1 |
| Sugimura, H | 2 |
| Stefan-van Staden, RI | 1 |
| Yamada, H | 1 |
| Natsume, H | 1 |
| Iwashita, Y | 1 |
| Szodorai, R | 1 |
| Szederjesi, J | 1 |
| Yari, D | 1 |
| Ehsanbakhsh, Z | 1 |
| Validad, MH | 1 |
| Langroudi, FH | 1 |
| Esfandiari, H | 1 |
| Prager, A | 1 |
| Hassanpour, K | 1 |
| Kurup, SP | 1 |
| Mets-Halgrimson, R | 1 |
| Yoon, H | 1 |
| Zeid, JL | 1 |
| Mets, MB | 1 |
| Rahmani, B | 1 |
| Araujo-Castillo, RV | 1 |
| Culquichicón, C | 1 |
| Solis Condor, R | 1 |
| Efendi, F | 1 |
| Sebayang, SK | 1 |
| Astutik, E | 1 |
| Hadisuyatmana, S | 1 |
| Has, EMM | 1 |
| Kuswanto, H | 1 |
| Foroutan, T | 1 |
| Ahmadi, F | 1 |
| Moayer, F | 1 |
| Khalvati, S | 1 |
| Zhang, Q | 2 |
| Lyu, Y | 1 |
| Huang, J | 1 |
| Yu, N | 1 |
| Wen, Z | 1 |
| Hou, H | 1 |
| Zhao, T | 1 |
| Gupta, A | 1 |
| Khosla, N | 1 |
| Govindasamy, V | 1 |
| Saini, A | 1 |
| Annapurna, K | 1 |
| Dhakate, SR | 1 |
| Akkaya, Ö | 1 |
| Chandgude, AL | 1 |
| Dömling, A | 1 |
| Harnett, J | 1 |
| Oakes, K | 1 |
| Carè, J | 1 |
| Leach, M | 1 |
| Brown, D | 1 |
| Cramer, H | 1 |
| Pinder, TA | 1 |
| Steel, A | 1 |
| Anheyer, D | 1 |
| Cantu, J | 1 |
| Valle, J | 1 |
| Flores, K | 1 |
| Gonzalez, D | 1 |
| Valdes, C | 1 |
| Lopez, J | 1 |
| Padilla, V | 1 |
| Alcoutlabi, M | 1 |
| Parsons, J | 1 |
| Núñez, K | 1 |
| Hamed, M | 1 |
| Fort, D | 1 |
| Bruce, D | 1 |
| Thevenot, P | 1 |
| Cohen, A | 1 |
| Weber, P | 1 |
| Menezes, AMB | 1 |
| Gonçalves, H | 1 |
| Perez-Padilla, R | 1 |
| Jarvis, D | 1 |
| de Oliveira, PD | 1 |
| Wehrmeister, FC | 1 |
| Mir, S | 1 |
| Wong, J | 1 |
| Ryan, CM | 1 |
| Bellingham, G | 1 |
| Singh, M | 2 |
| Waseem, R | 1 |
| Eckert, DJ | 1 |
| Chung, F | 1 |
| Hegde, H | 1 |
| Shimpi, N | 1 |
| Panny, A | 1 |
| Glurich, I | 1 |
| Christie, P | 1 |
| Acharya, A | 1 |
| English, KL | 1 |
| Downs, M | 1 |
| Goetchius, E | 1 |
| Buxton, R | 1 |
| Ryder, JW | 1 |
| Ploutz-Snyder, R | 1 |
| Guilliams, M | 1 |
| Scott, JM | 1 |
| Ploutz-Snyder, LL | 1 |
| Martens, C | 1 |
| Goplen, FK | 1 |
| Aasen, T | 1 |
| Gjestad, R | 1 |
| Nordfalk, KF | 1 |
| Nordahl, SHG | 1 |
| Inoue, T | 1 |
| Soshi, S | 1 |
| Kubota, M | 1 |
| Marumo, K | 1 |
| Mortensen, NP | 1 |
| Caffaro, MM | 1 |
| Patel, PR | 2 |
| Uddin, MJ | 1 |
| Aravamudhan, S | 1 |
| Sumner, SJ | 1 |
| Fennell, TR | 1 |
| Gal, RL | 1 |
| Cohen, NJ | 1 |
| Kruger, D | 1 |
| Beck, RW | 1 |
| Bergenstal, RM | 1 |
| Calhoun, P | 1 |
| Cushman, T | 1 |
| Haban, A | 1 |
| Hood, K | 1 |
| Johnson, ML | 1 |
| McArthur, T | 1 |
| Olson, BA | 1 |
| Weinstock, RS | 1 |
| Oser, SM | 1 |
| Oser, TK | 1 |
| Bugielski, B | 1 |
| Strayer, H | 1 |
| Aleppo, G | 1 |
| Maruyama, H | 1 |
| Hirayama, K | 1 |
| Yamashita, M | 1 |
| Ohgi, K | 1 |
| Tsujimoto, R | 1 |
| Takayasu, M | 1 |
| Shimohata, H | 1 |
| Kobayashi, M | 1 |
| Buscagan, TM | 1 |
| Rees, DC | 1 |
| Jaborek, JR | 1 |
| Zerby, HN | 1 |
| Wick, MP | 1 |
| Fluharty, FL | 1 |
| Moeller, SJ | 1 |
| Razavi, P | 1 |
| Dickler, MN | 1 |
| Shah, PD | 1 |
| Toy, W | 1 |
| Brown, DN | 1 |
| Won, HH | 1 |
| Li, BT | 1 |
| Shen, R | 1 |
| Vasan, N | 1 |
| Modi, S | 1 |
| Jhaveri, K | 1 |
| Caravella, BA | 1 |
| Patil, S | 1 |
| Selenica, P | 1 |
| Zamora, S | 1 |
| Cowan, AM | 1 |
| Comen, E | 1 |
| Singh, A | 1 |
| Covey, A | 1 |
| Berger, MF | 1 |
| Hudis, CA | 1 |
| Norton, L | 1 |
| Nagy, RJ | 1 |
| Odegaard, JI | 1 |
| Lanman, RB | 1 |
| Solit, DB | 1 |
| Robson, ME | 1 |
| Lacouture, ME | 1 |
| Brogi, E | 1 |
| Reis-Filho, JS | 1 |
| Moynahan, ME | 1 |
| Scaltriti, M | 1 |
| Chandarlapaty, S | 1 |
| Papouskova, K | 1 |
| Moravcova, M | 1 |
| Masrati, G | 1 |
| Ben-Tal, N | 1 |
| Sychrova, H | 1 |
| Zimmermannova, O | 1 |
| Fang, J | 2 |
| Fan, Y | 1 |
| Luo, T | 2 |
| Su, H | 1 |
| Tsetseris, L | 1 |
| Anthopoulos, TD | 1 |
| Liu, SF | 1 |
| Zhao, K | 1 |
| Sacan, O | 1 |
| Turkyilmaz, IB | 1 |
| Bayrak, BB | 1 |
| Mutlu, O | 1 |
| Akev, N | 1 |
| Yanardag, R | 3 |
| Gruber, S | 1 |
| Kamnoedboon, P | 1 |
| Özcan, M | 1 |
| Srinivasan, M | 1 |
| Jo, YH | 1 |
| Oh, HK | 1 |
| Jeong, SY | 1 |
| Lee, BG | 1 |
| Zheng, J | 1 |
| Guan, H | 1 |
| Li, D | 2 |
| Tan, H | 1 |
| Maji, TK | 1 |
| J R, A | 1 |
| Mukherjee, S | 1 |
| Alexander, R | 1 |
| Mondal, A | 1 |
| Das, S | 1 |
| Sharma, RK | 1 |
| Chakraborty, NK | 1 |
| Dasgupta, K | 1 |
| Sharma, AMR | 1 |
| Hawaldar, R | 1 |
| Pandey, M | 1 |
| Naik, A | 1 |
| Majumdar, K | 1 |
| Pal, SK | 1 |
| Adarsh, KV | 1 |
| Ray, SK | 1 |
| Karmakar, D | 1 |
| Ma, Y | 3 |
| Gao, W | 1 |
| Ma, S | 1 |
| Lin, W | 1 |
| Zhou, T | 1 |
| Wu, T | 1 |
| Wu, Q | 1 |
| Ye, C | 1 |
| He, X | 1 |
| Jiang, F | 1 |
| Yuan, D | 1 |
| Chen, Q | 1 |
| Hong, M | 1 |
| Chen, K | 1 |
| Hussain, M | 1 |
| Razi, SS | 1 |
| Yildiz, EA | 1 |
| Zhao, J | 1 |
| Yaglioglu, HG | 1 |
| Donato, MD | 1 |
| Jiang, J | 1 |
| Jamil, MI | 1 |
| Zhan, X | 1 |
| Chen, F | 1 |
| Cheng, D | 1 |
| Wu, CT | 1 |
| Utsunomiya, T | 1 |
| Ichii, T | 1 |
| Fujinami, S | 1 |
| Nakajima, K | 1 |
| Sanchez, DM | 1 |
| Raucci, U | 1 |
| Ferreras, KN | 1 |
| Martínez, TJ | 1 |
| Mordi, NA | 1 |
| Mordi, IR | 1 |
| Singh, JS | 1 |
| McCrimmon, RJ | 1 |
| Struthers, AD | 1 |
| Lang, CC | 1 |
| Wang, XW | 1 |
| Yuan, LJ | 1 |
| Yang, Y | 1 |
| Chen, WF | 1 |
| Luo, R | 1 |
| Yang, K | 1 |
| Amarasiri, SS | 1 |
| Attanayake, AP | 1 |
| Arawwawala, LDAM | 1 |
| Jayatilaka, KAPW | 1 |
| Mudduwa, LKB | 1 |
| Ogunsuyi, O | 2 |
| Akanni, O | 1 |
| Alabi, O | 1 |
| Alimba, C | 1 |
| Adaramoye, O | 1 |
| Cambier, S | 1 |
| Eswara, S | 1 |
| Gutleb, AC | 1 |
| Bakare, A | 1 |
| Gu, Z | 1 |
| Cong, J | 1 |
| Pellegrini, M | 1 |
| Palmieri, S | 1 |
| Ricci, A | 1 |
| Serio, A | 1 |
| Paparella, A | 1 |
| Lo Sterzo, C | 1 |
| Jadeja, SD | 1 |
| Vaishnav, J | 1 |
| Mansuri, MS | 1 |
| Shah, C | 1 |
| Mayatra, JM | 1 |
| Shah, A | 1 |
| Begum, R | 1 |
| Song, H | 2 |
| Lian, Y | 1 |
| Wan, T | 1 |
| Schultz-Lebahn, A | 1 |
| Skipper, MT | 1 |
| Hvas, AM | 1 |
| Larsen, OH | 1 |
| Hijazi, Z | 1 |
| Granger, CB | 1 |
| Hohnloser, SH | 1 |
| Westerbergh, J | 1 |
| Lindbäck, J | 1 |
| Alexander, JH | 1 |
| Keltai, M | 1 |
| Parkhomenko, A | 1 |
| López-Sendón, JL | 1 |
| Lopes, RD | 1 |
| Siegbahn, A | 1 |
| Wallentin, L | 1 |
| El-Tarabany, MS | 1 |
| Saleh, AA | 1 |
| El-Araby, IE | 1 |
| El-Magd, MA | 1 |
| van Ginkel, MPH | 1 |
| Schijven, MP | 1 |
| van Grevenstein, WMU | 1 |
| Schreuder, HWR | 1 |
| Pereira, EDM | 1 |
| da Silva, J | 1 |
| Carvalho, PDS | 1 |
| Grivicich, I | 1 |
| Picada, JN | 1 |
| Salgado Júnior, IB | 1 |
| Vasques, GJ | 1 |
| Pereira, MADS | 1 |
| Reginatto, FH | 1 |
| Ferraz, ABF | 1 |
| Vasilenko, EA | 1 |
| Gorshkova, EN | 1 |
| Astrakhantseva, IV | 1 |
| Drutskaya, MS | 1 |
| Tillib, SV | 1 |
| Nedospasov, SA | 1 |
| Mokhonov, VV | 1 |
| Nam, YW | 1 |
| Cui, M | 1 |
| Orfali, R | 1 |
| Viegas, A | 1 |
| Nguyen, M | 1 |
| Mohammed, EHM | 1 |
| Zoghebi, KA | 1 |
| Rahighi, S | 1 |
| Parang, K | 1 |
| Patterson, KC | 1 |
| Kahanovitch, U | 1 |
| Gonçalves, CM | 1 |
| Hablitz, JJ | 1 |
| Staruschenko, A | 1 |
| Mulkey, DK | 1 |
| Olsen, ML | 1 |
| Gu, L | 1 |
| Cao, X | 1 |
| Mukhtar, A | 1 |
| Wu, K | 1 |
| Zhang, YY | 1 |
| Zhu, Y | 1 |
| Lu, DZ | 1 |
| Dong, W | 1 |
| Bi, WJ | 1 |
| Feng, XJ | 1 |
| Wen, LM | 1 |
| Sun, H | 1 |
| Qi, MC | 1 |
| Chang, CC | 1 |
| Dinh, TK | 1 |
| Lee, YA | 1 |
| Wang, FN | 1 |
| Sung, YC | 1 |
| Yu, PL | 1 |
| Chiu, SC | 1 |
| Shih, YC | 1 |
| Wu, CY | 1 |
| Huang, YD | 1 |
| Lu, TT | 1 |
| Wan, D | 1 |
| Sakizadeh, J | 1 |
| Cline, JP | 1 |
| Snyder, MA | 1 |
| Kiely, CJ | 1 |
| McIntosh, S | 1 |
| Jiang, X | 1 |
| Cao, JW | 1 |
| Zhao, CK | 1 |
| Yang, R | 1 |
| Zhang, QY | 1 |
| Chen, KJ | 2 |
| Liu, H | 3 |
| He, Z | 1 |
| Chen, B | 1 |
| Wu, J | 2 |
| Du, X | 1 |
| Moore, J | 1 |
| Blank, BR | 1 |
| Eksterowicz, J | 1 |
| Sutimantanapi, D | 1 |
| Yuen, N | 1 |
| Metzger, T | 1 |
| Chan, B | 1 |
| Huang, T | 1 |
| Chen, X | 1 |
| Duong, F | 1 |
| Kong, W | 1 |
| Chang, JH | 1 |
| Sun, J | 1 |
| Zavorotinskaya, T | 1 |
| Ye, Q | 1 |
| Junttila, MR | 1 |
| Ndubaku, C | 1 |
| Friedman, LS | 1 |
| Fantin, VR | 1 |
| Sun, D | 1 |
| Fei, P | 1 |
| Xie, Q | 1 |
| Jiang, Y | 1 |
| Feng, H | 1 |
| Chang, Y | 1 |
| Kang, H | 1 |
| Xing, M | 1 |
| Chen, J | 1 |
| Shao, Z | 1 |
| Yuan, C | 1 |
| Wu, Y | 2 |
| Allan, R | 1 |
| Canham, K | 1 |
| Wallace, R | 1 |
| Singh, D | 1 |
| Ward, J | 1 |
| Cooper, A | 1 |
| Newcomb, C | 1 |
| Nammour, S | 1 |
| El Mobadder, M | 1 |
| Maalouf, E | 1 |
| Namour, M | 1 |
| Namour, A | 1 |
| Rey, G | 1 |
| Matamba, P | 1 |
| Matys, J | 1 |
| Zeinoun, T | 1 |
| Grzech-Leśniak, K | 1 |
| Segabinazi Peserico, C | 1 |
| Garozi, L | 1 |
| Zagatto, AM | 1 |
| Machado, FA | 1 |
| Hirth, JM | 1 |
| Dinehart, EE | 1 |
| Lin, YL | 1 |
| Kuo, YF | 1 |
| Nouri, SS | 1 |
| Ritchie, C | 1 |
| Volow, A | 1 |
| Li, B | 2 |
| McSpadden, S | 1 |
| Dearman, K | 1 |
| Kotwal, A | 1 |
| Sudore, RL | 1 |
| Ward, L | 1 |
| Thakur, A | 1 |
| Kondadasula, SV | 1 |
| Ji, K | 1 |
| Schalk, DL | 1 |
| Bliemeister, E | 1 |
| Ung, J | 1 |
| Aboukameel, A | 1 |
| Casarez, E | 1 |
| Sloane, BF | 1 |
| Lum, LG | 1 |
| Xiao, M | 1 |
| Feng, X | 1 |
| Gao, R | 1 |
| Du, B | 1 |
| Brooks, T | 1 |
| Zwirner, J | 1 |
| Hammer, N | 1 |
| Ondruschka, B | 1 |
| Jermy, M | 1 |
| Luengo, A | 1 |
| Marzo, I | 1 |
| Reback, M | 1 |
| Daubit, IM | 1 |
| Fernández-Moreira, V | 1 |
| Metzler-Nolte, N | 1 |
| Gimeno, MC | 1 |
| Tonchev, I | 1 |
| Heberman, D | 1 |
| Peretz, A | 1 |
| Medvedovsky, AT | 1 |
| Gotsman, I | 1 |
| Rashi, Y | 1 |
| Poles, L | 1 |
| Goland, S | 1 |
| Perlman, GY | 1 |
| Danenberg, HD | 1 |
| Beeri, R | 1 |
| Shuvy, M | 1 |
| Fu, Q | 1 |
| Yang, D | 1 |
| Sarapulova, A | 1 |
| Pang, Q | 1 |
| Meng, Y | 1 |
| Wei, L | 1 |
| Ehrenberg, H | 1 |
| Kim, CC | 1 |
| Jeong, SH | 1 |
| Oh, KH | 1 |
| Nam, KT | 1 |
| Sun, JY | 1 |
| Ning, J | 1 |
| Duan, Z | 1 |
| Kershaw, SV | 1 |
| Rogach, AL | 1 |
| Gao, Z | 1 |
| Wang, T | 1 |
| Li, Q | 1 |
| Cao, T | 1 |
| Guo, L | 1 |
| Fu, Y | 1 |
| Seeger, ZL | 1 |
| Izgorodina, EI | 1 |
| Hue, S | 1 |
| Beldi-Ferchiou, A | 1 |
| Bendib, I | 1 |
| Surenaud, M | 1 |
| Fourati, S | 1 |
| Frapard, T | 1 |
| Rivoal, S | 1 |
| Razazi, K | 1 |
| Carteaux, G | 1 |
| Delfau-Larue, MH | 1 |
| Mekontso-Dessap, A | 1 |
| Audureau, E | 1 |
| de Prost, N | 1 |
| Gao, SS | 1 |
| Duangthip, D | 1 |
| Lo, ECM | 1 |
| Chu, CH | 1 |
| Roberts, W | 1 |
| Rosenheck, RA | 1 |
| Miyake, T | 1 |
| Kimoto, E | 1 |
| Luo, L | 1 |
| Mathialagan, S | 1 |
| Horlbogen, LM | 1 |
| Ramanathan, R | 1 |
| Wood, LS | 1 |
| Johnson, JG | 1 |
| Le, VH | 1 |
| Vourvahis, M | 1 |
| Rodrigues, AD | 1 |
| Muto, C | 1 |
| Furihata, K | 1 |
| Sugiyama, Y | 1 |
| Kusuhara, H | 1 |
| Gong, Q | 1 |
| Song, W | 1 |
| Sun, B | 1 |
| Cao, P | 1 |
| Gu, S | 1 |
| Sun, X | 2 |
| Zhou, G | 1 |
| Toma, C | 1 |
| Khandhar, S | 1 |
| Zalewski, AM | 1 |
| D'Auria, SJ | 1 |
| Tu, TM | 1 |
| Jaber, WA | 1 |
| Cho, J | 2 |
| Suwandaratne, NS | 1 |
| Razek, S | 1 |
| Choi, YH | 1 |
| Piper, LFJ | 1 |
| Watson, DF | 1 |
| Banerjee, S | 1 |
| Xie, S | 1 |
| Lindsay, AP | 1 |
| Bates, FS | 1 |
| Lodge, TP | 1 |
| Hao, Y | 1 |
| Chapovetsky, A | 1 |
| Liu, JJ | 1 |
| Welborn, M | 1 |
| Luna, JM | 1 |
| Do, T | 1 |
| Haiges, R | 1 |
| Miller Iii, TF | 1 |
| Marinescu, SC | 1 |
| Lopez, SA | 1 |
| Compter, I | 1 |
| Eekers, DBP | 1 |
| Hoeben, A | 1 |
| Rouschop, KMA | 1 |
| Reymen, B | 1 |
| Ackermans, L | 1 |
| Beckervordersantforth, J | 1 |
| Bauer, NJC | 1 |
| Anten, MM | 1 |
| Wesseling, P | 1 |
| Postma, AA | 1 |
| De Ruysscher, D | 1 |
| Lambin, P | 1 |
| Qiang, L | 1 |
| Yang, S | 1 |
| Cui, YH | 1 |
| He, YY | 1 |
| Kumar, SK | 1 |
| Jacobus, SJ | 1 |
| Cohen, AD | 1 |
| Weiss, M | 1 |
| Callander, N | 1 |
| Singh, AK | 1 |
| Parker, TL | 1 |
| Menter, A | 1 |
| Parsons, B | 1 |
| Kumar, P | 1 |
| Kapoor, P | 1 |
| Rosenberg, A | 1 |
| Zonder, JA | 1 |
| Faber, E | 1 |
| Lonial, S | 1 |
| Anderson, KC | 1 |
| Richardson, PG | 1 |
| Orlowski, RZ | 1 |
| Wagner, LI | 1 |
| Rajkumar, SV | 1 |
| Li, G | 1 |
| Hou, G | 1 |
| Cui, J | 1 |
| Xie, H | 1 |
| Sun, Z | 1 |
| Fang, Z | 1 |
| Dunstand-Guzmán, E | 1 |
| Hallal-Calleros, C | 1 |
| Hernández-Velázquez, VM | 1 |
| Canales-Vargas, EJ | 1 |
| Domínguez-Roldan, R | 1 |
| Pedernera, M | 1 |
| Peña-Chora, G | 1 |
| Flores-Pérez, I | 1 |
| Kim, MJ | 1 |
| Han, C | 1 |
| White, K | 1 |
| Park, HJ | 1 |
| Ding, D | 1 |
| Boyd, K | 1 |
| Rothenberger, C | 1 |
| Bose, U | 1 |
| Carmichael, P | 1 |
| Linser, PJ | 1 |
| Tanokura, M | 1 |
| Salvi, R | 1 |
| Someya, S | 1 |
| Samuni, A | 1 |
| Goldstein, S | 1 |
| Divya, KP | 1 |
| Dharuman, V | 1 |
| Feng, J | 2 |
| Qian, Y | 1 |
| Cheng, Q | 1 |
| Ma, H | 1 |
| Ren, X | 1 |
| Wei, Q | 1 |
| Pan, W | 1 |
| Guo, J | 1 |
| Situ, B | 1 |
| An, T | 1 |
| Zheng, L | 1 |
| Augusto, S | 1 |
| Ratola, N | 1 |
| Tarín-Carrasco, P | 1 |
| Jiménez-Guerrero, P | 1 |
| Turco, M | 1 |
| Schuhmacher, M | 1 |
| Costa, S | 1 |
| Teixeira, JP | 1 |
| Costa, C | 1 |
| Syed, A | 1 |
| Marraiki, N | 1 |
| Al-Rashed, S | 1 |
| Elgorban, AM | 1 |
| Yassin, MT | 1 |
| Chankhanittha, T | 1 |
| Nanan, S | 1 |
| Sorokina, KN | 1 |
| Samoylova, YV | 1 |
| Gromov, NV | 1 |
| Ogorodnikova, OL | 1 |
| Parmon, VN | 1 |
| Ye, J | 1 |
| Liao, W | 1 |
| Zhang, P | 1 |
| Nabi, M | 1 |
| Cai, Y | 1 |
| Li, F | 1 |
| Alsbou, EM | 1 |
| Omari, KW | 1 |
| Adeosun, WA | 1 |
| Asiri, AM | 1 |
| Marwani, HM | 1 |
| Barral, M | 1 |
| Jemal-Turki, A | 1 |
| Beuvon, F | 1 |
| Soyer, P | 1 |
| Camparo, P | 1 |
| Cornud, F | 1 |
| Atwater, BD | 1 |
| Jones, WS | 1 |
| Loring, Z | 1 |
| Friedman, DJ | 1 |
| Namburath, M | 1 |
| Papirio, S | 1 |
| Moscariello, C | 1 |
| Di Costanzo, N | 1 |
| Pirozzi, F | 1 |
| Alappat, BJ | 1 |
| Sreekrishnan, TR | 1 |
| Volpin, F | 1 |
| Woo, YC | 1 |
| Kim, H | 2 |
| Freguia, S | 1 |
| Jeong, N | 1 |
| Choi, JS | 1 |
| Phuntsho, S | 1 |
| Shon, HK | 1 |
| Domínguez-Zambrano, E | 1 |
| Pedraza-Chaverri, J | 2 |
| López-Santos, AL | 1 |
| Medina-Campos, ON | 2 |
| Cruz-Rivera, C | 1 |
| Bueno-Hernández, F | 1 |
| Espinosa-Cuevas, A | 1 |
| Bulavaitė, A | 1 |
| Dalgediene, I | 1 |
| Michailoviene, V | 1 |
| Pleckaityte, M | 1 |
| Sauerbier, P | 1 |
| Köhler, R | 1 |
| Renner, G | 1 |
| Militz, H | 1 |
| Itano, S | 1 |
| Kadoya, H | 1 |
| Satoh, M | 1 |
| Nakamura, T | 2 |
| Murase, T | 2 |
| Sasaki, T | 1 |
| Kanwar, YS | 1 |
| Kashihara, N | 1 |
| Nasri, M | 1 |
| Adibhesami, G | 1 |
| Mahdavifard, S | 1 |
| Babaeenezhad, E | 1 |
| Ahmadvand, H | 1 |
| Nampei, M | 1 |
| Satoh, E | 1 |
| Akari, S | 1 |
| Katoh, N | 1 |
| Mizukami, H | 1 |
| Nna, VU | 1 |
| Abu Bakar, AB | 1 |
| Zakaria, Z | 1 |
| Othman, ZA | 1 |
| Jalil, NAC | 1 |
| Mohamed, M | 1 |
| Toyoki, D | 1 |
| Shibata, S | 1 |
| Kuribayashi-Okuma, E | 1 |
| Xu, N | 1 |
| Ishizawa, K | 1 |
| Hosoyamada, M | 1 |
| Uchida, S | 1 |
| Hou, X | 2 |
| Yuan, X | 1 |
| Cui, L | 1 |
| Ma, L | 1 |
| Cheng, X | 1 |
| Xin, Y | 1 |
| Zhang, K | 1 |
| Ren, W | 1 |
| Sun, R | 1 |
| Jia, Z | 1 |
| Tian, Z | 1 |
| Mi, QS | 1 |
| Foster, SR | 1 |
| Dilworth, LL | 1 |
| Omoruyi, FO | 1 |
| Thompson, R | 1 |
| Alexander-Lindo, RL | 1 |
| Cao, H | 1 |
| Wei, X | 1 |
| Cheng, P | 1 |
| Jiao, R | 1 |
| Xing, Y | 1 |
| Tang, J | 1 |
| Li, T | 1 |
| Han, H | 1 |
| Lee, JS | 1 |
| Shin, S | 1 |
| Lee, J | 1 |
| Kim, J | 1 |
| Cho, SW | 1 |
| Seo, J | 1 |
| Lee, T | 1 |
| Liu, YW | 1 |
| Hao, YC | 1 |
| Yin, SY | 1 |
| Zhang, MY | 1 |
| Kong, L | 1 |
| Wang, TY | 1 |
| Mudassir, HA | 1 |
| Qureshi, SA | 1 |
| Azmi, MB | 1 |
| Ahsan, M | 1 |
| Ma, J | 2 |
| Hu, MT | 1 |
| Dong, XD | 1 |
| Xiang, LT | 1 |
| Gu, QR | 1 |
| Du, ZY | 1 |
| Chen, SM | 2 |
| Chen, GR | 2 |
| Zhu, DD | 1 |
| Wang, YZ | 1 |
| She, XP | 1 |
| Zheng, Z | 1 |
| Guo, XX | 1 |
| Wang, K | 1 |
| Ji, BP | 1 |
| Zhou, F | 1 |
| Lai, X | 1 |
| Tong, D | 1 |
| Ai, X | 1 |
| Luo, Y | 1 |
| Zuo, F | 1 |
| Wei, Z | 1 |
| Jiang, Q | 1 |
| Meng, X | 1 |
| Zeng, Y | 1 |
| Wang, P | 1 |
| Thounaojam, MC | 1 |
| Montemari, A | 1 |
| Powell, FL | 1 |
| Malla, P | 1 |
| Gutsaeva, DR | 1 |
| Bachettoni, A | 1 |
| Ripandelli, G | 1 |
| Repossi, A | 1 |
| Tawfik, A | 1 |
| Martin, PM | 1 |
| Facchiano, F | 1 |
| Bartoli, M | 1 |
| Chege, BM | 1 |
| Waweru, MP | 1 |
| Frederick, B | 1 |
| Nyaga, NM | 1 |
| Sheela, N | 1 |
| Jose, MA | 1 |
| Sathyamurthy, D | 1 |
| Kumar, BN | 1 |
| Guan, M | 1 |
| Xie, L | 1 |
| Diao, C | 1 |
| Wang, N | 1 |
| Gao, H | 1 |
| Sellamuthu, PS | 1 |
| Arulselvan, P | 2 |
| Fakurazi, S | 1 |
| Kandasamy, M | 1 |
| Cicerchi, C | 1 |
| Li, N | 1 |
| Kratzer, J | 1 |
| Garcia, G | 1 |
| Roncal-Jimenez, CA | 1 |
| Tanabe, K | 1 |
| Hunter, B | 1 |
| Rivard, CJ | 1 |
| Sautin, YY | 1 |
| Gaucher, EA | 1 |
| Johnson, RJ | 1 |
| Lanaspa, MA | 1 |
| Ran, J | 1 |
| Tan, R | 1 |
| Lao, G | 1 |
| Kandasamy, N | 1 |
| Ashokkumar, N | 1 |
| El-Megharbel, SM | 1 |
| Hamza, RZ | 1 |
| Refat, MS | 2 |
| Balakumar, P | 1 |
| Varatharajan, R | 1 |
| Nyo, YH | 1 |
| Renushia, R | 1 |
| Raaginey, D | 1 |
| Oh, AN | 1 |
| Akhtar, SS | 1 |
| Rupeshkumar, M | 1 |
| Sundram, K | 1 |
| Dhanaraj, SA | 1 |
| Malardé, L | 1 |
| Groussard, C | 1 |
| Lefeuvre-Orfila, L | 1 |
| Vincent, S | 1 |
| Efstathiou, T | 1 |
| Gratas-Delamarche, A | 1 |
| Juárez-Reyes, K | 1 |
| Brindis, F | 1 |
| Bye, R | 1 |
| Linares, E | 1 |
| Mata, R | 1 |
| Baş, H | 1 |
| Kalender, Y | 1 |
| Zeng, CC | 1 |
| Liu, WW | 1 |
| Cheng, JG | 1 |
| Réggami, Y | 1 |
| Berredjem, H | 1 |
| Cheloufi, H | 1 |
| Berredjem, M | 1 |
| Bouzerna, N | 1 |
| Selim, ME | 1 |
| Hendi, AA | 1 |
| Alfallaj, E | 1 |
| Han, JW | 1 |
| Shim, DW | 1 |
| Shin, WY | 1 |
| Kim, MK | 1 |
| Shim, EJ | 1 |
| Koppula, S | 1 |
| Kim, TJ | 1 |
| Kang, TB | 1 |
| Lee, KH | 1 |
| Pourfarjam, Y | 1 |
| Rezagholizadeh, L | 1 |
| Nowrouzi, A | 1 |
| Meysamie, A | 1 |
| Ghaseminejad, S | 1 |
| Ziamajidi, N | 1 |
| Norouzi, D | 1 |
| Rupérez, FJ | 1 |
| García-Martínez, D | 1 |
| Baena, B | 1 |
| Maeso, N | 1 |
| Cifuentes, A | 1 |
| Barbas, C | 1 |
| Teixeira de Lemos, E | 1 |
| Reis, F | 1 |
| Baptista, S | 1 |
| Pinto, R | 1 |
| Sepodes, B | 1 |
| Vala, H | 1 |
| Rocha-Pereira, P | 1 |
| Correia da Silva, G | 1 |
| Teixeira, N | 1 |
| Silva, AS | 1 |
| Carvalho, L | 1 |
| Teixeira, F | 1 |
| Das, UN | 1 |
| Medvedeva, NB | 1 |
| Telushkin, PL | 1 |
| Stel'makh, AY | 1 |
| Mallick, C | 1 |
| De, D | 1 |
| Ghosh, D | 1 |
| Liu, S | 1 |
| Wang, XM | 1 |
| Duan, H | 1 |
| Rotimi, SO | 1 |
| Olayiwola, I | 1 |
| Ademuyiwa, O | 1 |
| Adamson, I | 1 |
| BAILEY, CC | 1 |
| BAILEY, OT | 1 |
| LEECH, RS | 1 |
| Latha, RC | 1 |
| Daisy, P | 2 |
| Vijayaraghavan, K | 1 |
| Iyyam Pillai, S | 1 |
| Subramanian, SP | 1 |
| Jaiswal, N | 1 |
| Bhatia, V | 1 |
| Srivastava, SP | 1 |
| Srivastava, AK | 1 |
| Tamrakar, AK | 1 |
| Haeri, MR | 1 |
| Limaki, HK | 1 |
| White, CJ | 1 |
| White, KN | 1 |
| Saipriya, K | 1 |
| Zharkova, NV | 1 |
| Potapov, PP | 1 |
| Stelmach, AY | 1 |
| Cheng, R | 1 |
| Lee, K | 1 |
| Hu, Y | 1 |
| Yi, J | 1 |
| Ma, JX | 1 |
| El-Shenawy, NS | 1 |
| Fakihi, FH | 1 |
| Damasceno, DC | 1 |
| Volpato, GT | 1 |
| de Mattos Paranhos Calderon, I | 1 |
| Cunha Rudge, MV | 1 |
| El-Remessy, AB | 1 |
| Behzadian, MA | 1 |
| Abou-Mohamed, G | 1 |
| Franklin, T | 1 |
| Caldwell, RW | 1 |
| Caldwell, RB | 1 |
| Matsumoto, S | 1 |
| Koshiishi, I | 1 |
| Inoguchi, T | 1 |
| Nawata, H | 1 |
| Utsumi, H | 1 |
| Korytár, P | 1 |
| Sivonová, M | 1 |
| Maruniaková, A | 1 |
| Ulicná, O | 1 |
| Kvasnicka, P | 1 |
| Liptáková, A | 1 |
| Bozek, P | 1 |
| Cársky, J | 1 |
| Duracková, Z | 1 |
| LOUBATIERES, A | 1 |
| BOUYARD, P | 1 |
| DE LACLOS, F | 1 |
| Garg, MC | 1 |
| Chaudhary, DP | 1 |
| Bansal, DD | 1 |
| Kim, YC | 1 |
| Lee, AK | 1 |
| Lee, JH | 1 |
| Lee, I | 1 |
| Lee, DC | 1 |
| Kim, SH | 1 |
| Kim, SG | 1 |
| Lee, MG | 1 |
| Ozsoy-Sacan, O | 1 |
| Orak, H | 1 |
| Ozgey, Y | 1 |
| Tunali, S | 1 |
| Galusha, SA | 1 |
| Rock, KL | 1 |
| Senthilkumar, GP | 1 |
| Sathish Kumar, D | 1 |
| Subramanian, S | 1 |
| Eidi, A | 1 |
| Eidi, M | 1 |
| Esmaeili, E | 1 |
| CONN, JW | 1 |
| LOUIS, LH | 1 |
| JOHNSTON, MW | 1 |
| Dominis, M | 1 |
| Rocic, S | 1 |
| Ashcroft, SJ | 2 |
| Rocic, B | 4 |
| Poje, M | 4 |
| Sikirica, M | 1 |
| Vicković, I | 1 |
| Bruvo, M | 1 |
| Asayama, K | 1 |
| Nakane, T | 1 |
| Uchida, N | 1 |
| Hayashibe, H | 1 |
| Dobashi, K | 1 |
| Nakazawa, S | 1 |
| Mitra, SK | 1 |
| Gopumadhavan, S | 1 |
| Muralidhar, TS | 1 |
| Anturlikar, SD | 1 |
| Sujatha, MB | 1 |
| Kristal, BS | 1 |
| Vigneau-Callahan, KE | 1 |
| Moskowitz, AJ | 1 |
| Matson, WR | 1 |
| Akimoto, LS | 1 |
| Pedrinho, SR | 1 |
| Bazotte, RB | 1 |
| Kawada, J | 1 |
| Harrison, DE | 1 |
| Rahman, MA | 2 |
| Schmidt, R | 2 |
| Methfessel, J | 2 |
| Schultka, R | 1 |
| Apel, D | 1 |
| Alam, MJ | 1 |
| Whitehouse, FW | 1 |
| Cleary, WJ | 1 |
| Keil, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2/3 Study of Effect of AT1RB Versus ACE Inhibitor in Addition to XO Inhibitor on Progression of LV Remodeling and Dysfunction in Diabetic Patients With Acute MI.[NCT01052272] | Phase 2/Phase 3 | 72 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
LVEF is a calculation of heart pump function determined from the volume after complete filling minus the volume after complete contraction divided by the volume after complete filling. A value of 55% or greater is normal. This is a measure of LV Systolic Function. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals for reporting purposes (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | percent (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,18,18) | Month 6(n=14,11,11,12) | Month 9(n=1,2,0,0) | Month 12(n=12,11,11,11) | Month 15(n=3,2,1,1) | Month 18(n=10,12,8,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 56.36 | 56.82 | 42.62 | 52.37 | 39.88 | 56.33 | NA | 51.70 | 54.17 |
| Candesartan Cilexetil and Allopurinol | 52.68 | 57.28 | NA | 56.11 | 54.46 | 57.82 | 56.17 | 55.79 | 54.40 |
| Ramipril | 52.19 | 54.20 | 64.98 | 52.76 | 52.13 | 55.02 | 51.27 | 57.18 | 50.73 |
| Ramipril and Allopurinol | 53.37 | 52.80 | NA | 51.74 | 34.89 | 54.05 | NA | 55.59 | NA |
LVEDV/BSA: As an indicator of heart size, the blood volume of the heart is related to the body size. The relation of heart blood volume to body size is more accurate in determining pathology because larger people require a larger heart blood volume. The values that are too high or too low indicate a diseased myocardium. This is a measure of LV Diastolic Function. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals. (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | ml/m^2 (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,18,18) | Month 6(n=14,11,11,12) | Month 9(n=1,2,0,0) | Month12(n=12,11,11,11) | Month 15(n=3,2,1,1) | Month 18(n=10,12,8,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 78.06 | 78.60 | 93.57 | 85.44 | 90.20 | 82.74 | NA | 84.28 | 76.65 |
| Candesartan Cilexetil and Allopurinol | 79.03 | 78.01 | NA | 79.75 | 63.1 | 84.95 | 75.27 | 79.72 | 75.05 |
| Ramipril | 73.03 | 74.10 | 73.23 | 75.34 | 81.19 | 75.28 | 71.99 | 70.46 | 48.68 |
| Ramipril and Allopurinol | 78.52 | 86.13 | NA | 83.95 | 108.25 | 67.96 | NA | 71.63 | NA |
LVESV/BSA: The end systolic volume is the blood volume of the heart at the end of contraction and is an index of the pump function of the heart. This relation to body size is more accurate in determining pathology because larger people require a larger heart blood volume. The values that are too high or too low indicate a diseased myocardium. This is a measure of LV Systolic Function. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals. (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | ml/m^2 (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,18,18) | Month 6(n=14,11,11,12) | Month 9(n=1,2,0,0) | Month 12(n=12,11,11,11) | Month 15(n=3,2,1,1) | Month 18(n=10,12,8,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 35.26 | 35.26 | 53.87 | 42.27 | 54.04 | 37.76 | NA | 41.72 | 35.13 |
| Candesartan Cilexetil and Allopurinol | 39.49 | 34.15 | NA | 36.07 | 28.74 | 37.18 | 32.99 | 35.99 | 34.22 |
| Ramipril | 36.20 | 34.77 | 25.64 | 36.82 | 39.42 | 35.30 | 35.23 | 31.17 | 23.98 |
| Ramipril and Allopurinol | 37.91 | 42.88 | NA | 42.34 | 70.48 | 30.39 | NA | 31.56 | NA |
LVED Mass/LVEDV: As an indicator of heart muscle mass and heart blood volume, the mass indexed to end diastolic volume determines whether there is an adequate amount of heart muscle to pump the heart blood volume obtained from a three-dimensional analysis. The values that are too high or too low indicate a diseased myocardium. This is a measure of LV Geometry. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals for reporting purposes. (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | g/ml (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,18,18) | Month 6(n=14,11,11,12) | Month 9(n=1,2,0,0) | Month 12(n=12,11,11,11) | Month 15(n=3,2,1,1) | Month 18(n=10,12,8,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 0.95 | 0.83 | 0.67 | 0.78 | 0.70 | 0.79 | NA | 0.80 | 0.64 |
| Candesartan Cilexetil and Allopurinol | 0.87 | 0.82 | NA | 0.86 | 0.68 | 0.80 | 0.69 | 0.82 | 0.69 |
| Ramipril | 0.92 | 0.87 | 0.75 | 0.84 | 0.81 | 0.79 | 0.95 | 0.84 | 0.93 |
| Ramipril and Allopurinol | 0.86 | 0.71 | NA | 0.72 | 0.57 | 0.83 | NA | 0.80 | NA |
LVED Radius/Wall thickness As an indicator of heart muscle mass and heart volume chamber diameter, the end-diastolic radius indexed to end diastolic wall thickness determines whether there is an adequate amount of heart muscle to pump the heart blood volume obtained from a two-dimensional analysis. The values that are too high or too low indicate a diseased myocardium. This is a measure of LV Geometry. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals for reporting purposes. (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | unitless (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,18,18) | Month 6(n=14,11,11,12) | Month 9(n=1,2,0,0) | Month 12(n=12,11,11,11) | Month 15(n=3,2,1,1) | Month 18(n=10,12,8,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 3.14 | 3.39 | 4.14 | 3.68 | 4.10 | 3.71 | NA | 3.58 | 4.04 |
| Candesartan Cilexetil and Allopurinol | 3.45 | 3.63 | NA | 3.42 | 3.90 | 3.56 | 4.24 | 3.56 | 4.29 |
| Ramipril | 3.23 | 3.32 | 3.42 | 3.43 | 3.44 | 3.60 | 2.92 | 3.46 | 3.12 |
| Ramipril and Allopurinol | 3.57 | 4.04 | NA | 4.01 | 4.57 | 3.60 | NA | 3.61 | NA |
By identifying three points in three different planes in the heart muscle, the maximum shortening is the average of the difference between the distance between these three points at the end of filling of the heart and the end of contraction divided by the length at the end of filling times 100. The maximum shortening is a three dimensional analysis. The higher values indicate a healthy heart. This is a measure of LV Systolic Function. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals for reporting purposes. (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | percent of length at end of filling (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,17,18) | Month 6(n=14,11,10,12) | Month 9(n=1,2,0,0) | Month 12(n=11,11,10,10) | Month 15(n=3,2,1,1) | Month 18(n=10,12,7,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 16.68 | 17.50 | 19.08 | 17.13 | 16.28 | 17.55 | NA | 16.62 | 20.38 |
| Candesartan Cilexetil and Allopurinol | 16.00 | 18.50 | NA | 18.51 | 16.36 | 17.52 | 17.89 | 17.85 | 16.59 |
| Ramipril | 15.81 | 16.88 | 18.43 | 14.57 | 17.06 | 17.26 | 16.68 | 15.67 | 13.70 |
| Ramipril and Allopurinol | 15.84 | 18.72 | NA | 17.96 | 14.22 | 17.46 | NA | 17.52 | NA |
The Peak Early Filling Rate Normalized to EDV is calculated from the slope of the volume during the early filling of the heart with respect to time. The higher values indicate a very healthy heart muscle and lower values are indicative of a very stiff muscle. This is a measure of LV Diastolic Function. Since some visits did not occur at the scheduled 6 month intervals, the results have been divided into 3-month visit intervals for reporting purposes. (NCT01052272)
Timeframe: 5 visits per Participant over 2 years (about every 6 months)
| Intervention | 1/sec (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Month 0 (n=17,17,18,18) | Month 6(n=14,11,11,12) | Month 9(n=1,2,0,0) | Month 12(n=12,11,11,11) | Month 15(n=3,2,1,1) | Month 18(n=10,12,8,8) | Month 21(n=3,0,0,1) | Month 24 (n=11,9,8,10) | Month 27 (n=1,1,0,1) | |
| Candesartan Cilexetil | 2.01 | 2.02 | 1.13 | 1.90 | 1.48 | 1.93 | NA | 1.65 | 1.10 |
| Candesartan Cilexetil and Allopurinol | 2.0 | 1.98 | NA | 1.77 | 2.28 | 2.05 | 2.50 | 1.82 | 2.15 |
| Ramipril | 1.93 | 1.74 | 2.50 | 1.80 | 2.02 | 1.91 | 1.69 | 2.05 | 1.34 |
| Ramipril and Allopurinol | 2.11 | 2.03 | NA | 1.93 | 1.56 | 1.89 | NA | 1.88 | NA |
2 reviews available for uric acid and Alloxan Diabetes
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
[New hypotheses for the mechanisms of streptozotocin and alloxan inducing diabetes mellitus].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alloxan; Animals; Diabetes Mellitus, Experimental; DN | 1992 |
1 trial available for uric acid and Alloxan Diabetes
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
81 other studies available for uric acid and Alloxan Diabetes
| Article | Year |
|---|---|
Antioxidation and Nrf2-mediated heme oxygenase-1 activation contribute to renal protective effects of hydralazine in diabetic nephropathy.
Topics: Allopurinol; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose | 2022 |
Assessment of redox state and biochemical parameters of salivary glands in streptozotocin-induced diabetic male rats treated with mate tea (Ilex paraguariensis).
Topics: Amylases; Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione; Glutathione | 2022 |
Oral sub-chronic treatment with Terminalia phaeocarpa Eichler (Combretaceae) reduces liver PTP1B activity in a murine model of diabetes.
Topics: Animals; Blood Glucose; Cholesterol; Combretaceae; Diabetes Mellitus, Experimental; Disease Models, | 2023 |
Inactivation of mitochondrial pyruvate carrier promotes NLRP3 inflammasome activation and gout development via metabolic reprogramming.
Topics: Animals; Diabetes Mellitus, Experimental; Gout; Hereditary Autoinflammatory Diseases; Inflammasomes; | 2023 |
Topics: Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Inflammation; Mice; Mi | 2023 |
Comparative impact of streptozotocin on altering normal glucose homeostasis in diabetic rats compared to normoglycemic rats.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Home | 2023 |
Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in Ins
Topics: Albuminuria; Ameloblasts; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease | 2020 |
Exogenous glutamine ameliorates diabetic nephropathy in a rat model of type 2 diabetes mellitus through its antioxidant and anti-inflammatory activities.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2023 |
Influence of xanthine oxidoreductase inhibitor, topiroxostat, on body weight of diabetic obese mice.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fatty Acids, Nonesterified | 2021 |
Malaysian Propolis and Metformin Synergistically Mitigate Kidney Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Creatinine; Diabetes Mellitus, Experimental; Diabet | 2021 |
Insulin stimulates uric acid reabsorption via regulating urate transporter 1 and ATP-binding cassette subfamily G member 2.
Topics: Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blood Gl | 2017 |
Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders.
Topics: Animals; Biomarkers; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Creatinine; Diabetes Mellit | 2018 |
Pancreatic and renal function in streptozotocin-induced type 2 diabetic rats administered combined inositol hexakisphosphate and inositol supplement.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Drug Thera | 2017 |
A Novel Multi-Epitope Vaccine Based on Urate Transporter 1 Alleviates Streptozotocin-Induced Diabetes by Producing Anti-URAT1 Antibody and an Immunomodulatory Effect in C57BL/6J Mice.
Topics: Animals; Antioxidants; Autoantibodies; Autoantigens; Cytokines; Diabetes Mellitus, Experimental; Dia | 2017 |
Single-Droplet Multiplex Bioassay on a Robust and Stretchable Extreme Wetting Substrate through Vacuum-Based Droplet Manipulation.
Topics: Animals; Biological Assay; Colorimetry; Diabetes Mellitus, Experimental; Dimethylpolysiloxanes; Gluc | 2018 |
Protective effects of sarsasapogenin against early stage of diabetic nephropathy in rats.
Topics: Anemarrhena; Animals; China; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese | 2018 |
Ethanolic seeds extract of Centratherum anthelminticum reduces oxidative stress in type 2 diabetes.
Topics: Alanine Transaminase; Animals; Antioxidants; Asteraceae; Bilirubin; Creatine Kinase; Diabetes Mellit | 2018 |
[Protective effects of Curcumin analogue L6H4 on kidney from type 2 diabetic rats].
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Curcumin; Diabetes Mellit | 2017 |
The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; | 2018 |
Stability of a type 2 diabetes rat model induced by high-fat diet feeding with low-dose streptozotocin injection.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; | 2018 |
Amelioration of diabetic nephropathy in db/db mice treated with tibetan medicine formula Siwei Jianghuang Decoction Powder extract.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Creatinine; Curcuma; Diabetes Mellitus, Experimental; D | 2018 |
Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy.
Topics: Allopurinol; Animals; Benzbromarone; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; | 2019 |
The freeze-dried extracts of Rotheca myricoides (Hochst.) Steane & Mabb possess hypoglycemic, hypolipidemic and hypoinsulinemic on type 2 diabetes rat model.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Freeze Drying; H | 2019 |
Effect of silymarin on streptozotocin-nicotinamide-induced type 2 diabetic nephropathy in rats.
Topics: Albuminuria; Animals; Blood Glucose; Case-Control Studies; Creatinine; Diabetes Mellitus, Experiment | 2013 |
Systemic perturbations of key metabolites in diabetic rats during the evolution of diabetes studied by urine metabonomics.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Discriminant | 2013 |
Beneficial effects of mangiferin isolated from Salacia chinensis on biochemical and hematological parameters in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Male; Phytotherapy; Rats; Rats, | 2014 |
Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids.
Topics: AMP Deaminase; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Experimental; Europe; Gene | 2014 |
Low protein diet inhibits uric acid synthesis and attenuates renal damage in streptozotocin-induced diabetic rats.
Topics: Albuminuria; Animals; Cell Proliferation; Cell Size; Diabetes Mellitus, Experimental; Diabetic Nephr | 2014 |
Protective effect of bioflavonoid myricetin enhances carbohydrate metabolic enzymes and insulin signaling molecules in streptozotocin-cadmium induced diabetic nephrotoxic rats.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Urea Nitrogen; Cadmium Chloride; Carbohydrate | 2014 |
Synthesis, spectroscopic, structural and thermal characterizations of vanadyl(IV) adenine complex prospective as antidiabetic drug agent.
Topics: Animals; Blood Glucose; Coordination Complexes; Creatinine; Diabetes Mellitus, Experimental; Electri | 2015 |
Fenofibrate and dipyridamole treatments in low-doses either alone or in combination blunted the development of nephropathy in diabetic rats.
Topics: Animals; Blood Glucose; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropat | 2014 |
Fermented soy permeate reduces cytokine level and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Diabet | 2015 |
Hypoglycemic, antihyperglycemic, and antioxidant effects of the edible plant Anoda cristata.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Flavones; Flavonoids; Free Ra | 2015 |
Nephrotoxic effects of lead nitrate exposure in diabetic and nondiabetic rats: Involvement of oxidative stress and the protective role of sodium selenite.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetes Mellitus, Experimental | 2016 |
Effect of β-anhydroicaritin on the expression levels of tumor necrosis factor-α and matrix metalloproteinase-3 in periodontal tissue of diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Body Weight; Carbohydrates; Diabetes Mellitus, Experimental; Im | 2015 |
[Protective effect of curcumin derivative B06 on kidney of type 2 diabetic rats].
Topics: Animals; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Curcumin; Diabetes Mellitus, Experimenta | 2015 |
Antihyperglycemic and antidiabetic effects of Ethyl (S)-2-(1-cyclohexylsulfamide carbamoyloxy) propanoate in streptozotocin-induced diabetic Wistar rats.
Topics: Animals; Atherosclerosis; Bilirubin; Blood Glucose; Body Weight; Carbamates; Creatinine; Diabetes Me | 2016 |
The possible counteractive effect of gold nanoparticles against streptozotocin-induced type 1 diabetes in young male albino rats.
Topics: Age Factors; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diab | 2016 |
Juniperus rigida Sieb. extract inhibits inflammatory responses via attenuation of TRIF-dependent signaling and inflammasome activation.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Prote | 2016 |
Effect of Cichorium intybus L. seed extract on renal parameters in experimentally induced early and late diabetes type 2 in rats.
Topics: Animals; Blood Glucose; Cichorium intybus; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nep | 2017 |
Evolution of oxidative stress parameters and response to oral vitamins E and C in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Ascorbic Acid; Diabetes Mellitus, Experimental; Female; Glutathione; | 2008 |
Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats.
Topics: Animals; Animals, Genetically Modified; Blood Glucose; Cholesterol; Cytokines; Diabetes Mellitus, Ex | 2009 |
Parameters of nitrogen metabolism during insulin hypoglycemia in rats with alloxan-induced diabetes.
Topics: Alloxan; Amino Acids; AMP Deaminase; Animals; Diabetes Mellitus, Experimental; Diabetic Coma; Glutam | 2008 |
Correction of protein metabolic disorders by composite extract of Musa paradisiaca and Coccinia indica in streptozotocin-induced diabetic albino rat: an approach through the pancreas.
Topics: Amidohydrolases; Animals; Blood Glucose; Cucurbitaceae; Diabetes Mellitus, Experimental; Glycated He | 2009 |
Peroxynitrite mediates glomerular lesion of diabetic rat via JAK/STAT signaling pathway.
Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; I | 2009 |
Inability of legumes to reverse diabetic-induced nephropathy in rats despite improvement in blood glucose and antioxidant status.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Proteins; Diabetes Mellitus, Experimental; D | 2010 |
Diabetes mellitus in rabbits injected with dialuric acid.
Topics: Animals; Barbiturates; Diabetes Mellitus, Experimental; Humans; Rabbits; Uric Acid | 1946 |
Insulin-secretagogue, antihyperlipidemic and other protective effects of gallic acid isolated from Terminalia bellerica Roxb. in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Blood Proteins; C-Peptide; Cholesterol; Creatinine; Diabetes Mellitus, Exper | 2011 |
Design, synthesis and characterization of zinc-3 hydroxy flavone, a novel zinc metallo complex for the treatment of experimental diabetes in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; C-Peptide; Creatinine; Di | 2012 |
Antidiabetic effect of Eclipta alba associated with the inhibition of alpha-glucosidase and aldose reductase.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Exp | 2012 |
Non-insulin dependent anti-diabetic activity of (2S, 3R, 4S) 4-hydroxyisoleucine of fenugreek (Trigonella foenum graecum) in streptozotocin-induced type I diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hypoglycemic Age | 2012 |
Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cassia; Creatinine; Diabetes Mellitus, Ex | 2012 |
Nitrogen metabolism in rats with experimental diabetes during acute alcohol intoxication.
Topics: Alcoholic Intoxication; Alloxan; Amino Acids; Aminohydrolases; Animals; Blood Urea Nitrogen; Central | 2011 |
Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy.
Topics: Aldehydes; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme | 2013 |
Decreasing the diabetic complication by vanadyl(VO)2+/vitamin B 6 complex in alloxan-induced diabetic mice.
Topics: Alloxan; Animals; Creatinine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glucosephosph | 2013 |
Oxidative stress and diabetes in pregnant rats.
Topics: Animals; Antioxidants; Congenital Abnormalities; Diabetes Mellitus, Experimental; Female; Gestationa | 2002 |
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.
Topics: Animals; Blood-Retinal Barrier; Body Weight; Diabetes Mellitus, Experimental; Endothelial Growth Fac | 2003 |
Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Allopurinol; Animals; Blood Glucose; Diabete | 2003 |
Influence of 2,5-dihydroxybenzylidene aminoguanidine on lipid oxidative damage and on antioxidant levels in model diabetes mellitus.
Topics: Aldehydes; Animals; Antioxidants; Benzyl Compounds; Blood Glucose; Cholesterol; Diabetes Mellitus, E | 2003 |
[Uric acid and diabetes mellitus].
Topics: Animals; Diabetes Mellitus, Experimental; Humans; Uric Acid | 1952 |
Effect of vitamin E supplementation on diabetes induced oxidative stress in experimental diabetes in rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Diabetes Mellitus, Experimental; Erythrocytes; Gluta | 2005 |
Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1,3-dimethyluric acid formation.
Topics: Administration, Oral; Alloxan; Aminophylline; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP | 2005 |
Protective effects of glurenorm (gliquidone) treatment on the liver injury of experimental diabetes.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Glucose; Dia | 2005 |
Vanadyl sulfate administration protects the streptozotocin-induced oxidative damage to brain tissue in rats.
Topics: Administration, Oral; Animals; Body Weight; Brain; Catalase; Diabetes Mellitus, Experimental; Glutat | 2006 |
Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model.
Topics: Adjuvants, Immunologic; Adoptive Transfer; Animals; Antigen-Presenting Cells; Antigens; Autoimmunity | 2006 |
Anti-diabetic effect of Murraya koenigii leaves on streptozotocin induced diabetic rats.
Topics: Animals; Blood Glucose; Blood Proteins; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetes Melli | 2006 |
Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Creatinine; | 2006 |
Metabolism of uric acid, glutathione and nitrogen, and excretion of 11-oxysteroids and 17-ketosteroids during induction of diabetes in man with pituitary adrenocorticotropic hormone.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Animals; Diabetes Mellitus, Experimental; Glutathione; | 1949 |
Diabetogenic action of alloxan-like compounds: cytotoxic effects of 5-hydroxy-pseudouric acid and dehydrouramil hydrate hydrochloride on rat pancreatic beta cells.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; Pyrimi | 1984 |
Oxidation of uric acid. 4. Synthesis, structure, and diabetogenic action of 5-imino-2,4,6(1H,3H,5H)-pyrimidinetrione salts and their alloxan-like covalent adducts.
Topics: Animals; Chemical Phenomena; Chemistry; Crystallography; Diabetes Mellitus, Experimental; Male; Oxid | 1983 |
Diabetogenic action of alloxan-like derivatives of uric acid.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Male; Rats; Uric Acid | 1980 |
Serum antioxidant status in streptozotocin-induced diabetic rat.
Topics: Animals; Antioxidants; Blood Glucose; Brain; Ceruloplasmin; Diabetes Mellitus, Experimental; Fructos | 1994 |
Effect of a herbomineral preparation D-400 in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Blood Urea Nitrogen; Cell Count; Creatinine; Diabetes | 1996 |
Purine catabolism: links to mitochondrial respiration and antioxidant defenses?
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Guanine; Guanosin | 1999 |
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In | 2000 |
Structure-activity relationships of alloxan-like compounds derived from uric acid.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; Rats; Rats, Inbred Le | 1986 |
Contribution of blood phosphate esters to the blood saccharoid fraction of rats with alloxan-induced diabetes or treated with insulin or epinephrine.
Topics: Animals; Ascorbic Acid; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Epinephrine; Ery | 1974 |
[Morphological and biochemical studies of the effect of barbituric acid, ureidosuccinic acid, orotic acid, uracil and thymine on the diabetogenic effect of alloxan].
Topics: Adrenal Glands; Alloxan; Amino Alcohols; Animals; Barbiturates; Blood Glucose; Diabetes Mellitus, Ex | 1968 |
Changes in the saccharoid fraction in rats with alloxan-induced diabetes or injected with epinephrine.
Topics: Alloxan; Animals; Ascorbic Acid; Blood Glucose; Creatine; Creatinine; Diabetes Mellitus, Experimenta | 1971 |
Diabetes mellitus in patients with gout.
Topics: Adult; Aged; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Glu | 1966 |
[On the effect of pyrimidines and their precursors on the diabetogenic activity of alloxan].
Topics: Alloxan; Animals; Aspartic Acid; Barbiturates; Blood Glucose; Cytosine; Diabetes Mellitus, Experimen | 1966 |