uric acid has been researched along with Allergy, Drug in 27 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and tolerability of allopurinol as the first-choice antihyperuricaemic treatment for gout, and compare the efficacy and tolerability of benzbromarone and probenecid as second-choice treatment." | 9.14 | Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. ( Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN, 2009) |
| "Allopurinol is the most commonly used urate-lowering therapy in gout." | 7.78 | Starting dose is a risk factor for allopurinol hypersensitivity syndrome: a proposed safe starting dose of allopurinol. ( Dalbeth, N; Dockerty, JL; Drake, J; Frampton, C; Jones, PB; Stamp, LK; Taylor, WJ, 2012) |
| "A patient with coexistent Klinefelter's syndrome, systemic lupus erythematosus (SLE) and chronic tophaceous gouty arthritis developed allopurinol hypersensitivity." | 7.67 | Allopurinol hypersensitivity in a patient with coexistent systemic lupus erythematosus and tophaceous gout. ( Fam, AG; McDonald, J; Paton, T; Senn, J, 1988) |
| "To investigate the efficacy and tolerability of allopurinol as the first-choice antihyperuricaemic treatment for gout, and compare the efficacy and tolerability of benzbromarone and probenecid as second-choice treatment." | 5.14 | Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol. ( Brouwers, JR; Delsing, J; Griep, EN; Hoekstra, M; Jansen, TL; Reinders, MK; van de Laar, MA; van Roon, EN, 2009) |
| "Allopurinol is the most commonly used urate-lowering therapy in gout." | 3.78 | Starting dose is a risk factor for allopurinol hypersensitivity syndrome: a proposed safe starting dose of allopurinol. ( Dalbeth, N; Dockerty, JL; Drake, J; Frampton, C; Jones, PB; Stamp, LK; Taylor, WJ, 2012) |
| "A patient with coexistent Klinefelter's syndrome, systemic lupus erythematosus (SLE) and chronic tophaceous gouty arthritis developed allopurinol hypersensitivity." | 3.67 | Allopurinol hypersensitivity in a patient with coexistent systemic lupus erythematosus and tophaceous gout. ( Fam, AG; McDonald, J; Paton, T; Senn, J, 1988) |
| "There have been recent reports of a characteristic hypersensitivity syndrome associated with the use of allopurinol." | 3.66 | Allpurinol hypersensitivity syndrome: effects and treatment. ( Evans, EF; Lindsey, SW, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kikuchi, A | 1 |
| Kigasawa, H | 1 |
| Tsurusawa, M | 1 |
| Kawa, K | 1 |
| Kikuta, A | 1 |
| Tsuchida, M | 1 |
| Nagatoshi, Y | 1 |
| Asami, K | 1 |
| Horibe, K | 1 |
| Makimoto, A | 1 |
| Tsukimoto, I | 1 |
| Perry, ME | 1 |
| Madhok, R | 1 |
| Simon, HB | 1 |
| Stamp, LK | 1 |
| Taylor, WJ | 1 |
| Jones, PB | 1 |
| Dockerty, JL | 1 |
| Drake, J | 1 |
| Frampton, C | 1 |
| Dalbeth, N | 1 |
| Wong, ML | 1 |
| Reinders, MK | 1 |
| van Roon, EN | 1 |
| Jansen, TL | 1 |
| Delsing, J | 1 |
| Griep, EN | 1 |
| Hoekstra, M | 1 |
| van de Laar, MA | 1 |
| Brouwers, JR | 1 |
| Earll, JM | 1 |
| Saavedra, M | 1 |
| Lombardo, JV | 1 |
| Terlinsky, A | 1 |
| Chester, AC | 1 |
| Preuss, HG | 1 |
| Urban, T | 1 |
| Maquarre, E | 1 |
| Housset, C | 1 |
| Chouaid, C | 1 |
| Devin, E | 1 |
| Lebeau, B | 1 |
| Umpiérrez, A | 1 |
| Cuesta-Herranz, J | 1 |
| De Las Heras, M | 1 |
| Lluch-Bernal, M | 1 |
| Figueredo, E | 1 |
| Sastre, J | 1 |
| Grahame, R | 1 |
| Simmonds, HA | 1 |
| McBride, MB | 1 |
| Marsh, FP | 1 |
| Fam, AG | 2 |
| Monev, SD | 1 |
| Hammer, B | 1 |
| Link, A | 1 |
| Wagner, A | 1 |
| Böhm, M | 1 |
| Butler, RC | 1 |
| Shah, SM | 1 |
| Grunow, WA | 1 |
| Texter, C | 1 |
| Lindsey, SW | 1 |
| Evans, EF | 1 |
| Glezer, GA | 1 |
| Casas, E | 1 |
| Puig, JG | 1 |
| Mateos, FA | 1 |
| Jiménez, ML | 1 |
| Michán, AD | 1 |
| Ramos, TH | 1 |
| McDonald, J | 1 |
| Paton, T | 1 |
| Senn, J | 1 |
| Field, MJ | 1 |
| Lawrence, JR | 1 |
| Pan, HY | 1 |
| Glazener, FS | 1 |
| Umeki, S | 1 |
| Ohga, R | 1 |
| Konishi, Y | 1 |
| Yasuda, T | 1 |
| Morimoto, K | 1 |
| Terao, A | 1 |
| Mănescu, N | 1 |
| Gluhovschi, G | 1 |
| Golea, O | 1 |
| Nicolcioiu, M | 1 |
| Schwarzkopf, A | 1 |
| Zosin, C | 1 |
| Hellström, PE | 1 |
| Repo, UK | 1 |
| Frayha, RA | 1 |
| Cowdry, SC | 1 |
| Shapiro, S | 1 |
| Storti, E | 1 |
| Quaglino, D | 1 |
3 reviews available for uric acid and Allergy, Drug
| Article | Year |
|---|---|
Difficult gout and new approaches for control of hyperuricemia in the allopurinol-allergic patient.
Topics: Allopurinol; Drug Hypersensitivity; Gout; Gout Suppressants; Humans; Kidney; Transplantation, Homolo | 2001 |
Complications of thiazide diuretic therapy: an update.
Topics: Alkalosis; Benzothiadiazines; Blood Volume; Coronary Disease; Death, Sudden; Diuretics; Drug Hyperse | 1986 |
Allopurinol. A review.
Topics: Adult; Allopurinol; Child; Drug Hypersensitivity; Drug Interactions; Gout; Humans; Iron; Kidney Dise | 1971 |
3 trials available for uric acid and Allergy, Drug
| Article | Year |
|---|---|
A study of rasburicase for the management of hyperuricemia in pediatric patients with newly diagnosed hematologic malignancies at high risk for tumor lysis syndrome.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Drug Hypersensi | 2009 |
Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol.
Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Admin | 2009 |
Capreomycin, ethambutol and rifampicin in apparently incurable pulmonary tuberculosis.
Topics: Adult; Aged; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic | 1969 |
21 other studies available for uric acid and Allergy, Drug
| Article | Year |
|---|---|
Treatment failure gout: failure to treat?
Topics: Allopurinol; Drug Hypersensitivity; General Practice; Gout; Gout Suppressants; Guideline Adherence; | 2010 |
On call. I've had gout for many years. I used to take Zyloprim without any problems, but I just had a severe allergic reaction, so my doctor switched me to Benemid. I'm doing okay, but the drug sometimes upsets my stomach. Do you have any suggestions?
Topics: Allopurinol; Drug Hypersensitivity; Gastritis; Gout; Gout Suppressants; Humans; Male; Middle Aged; P | 2010 |
Starting dose is a risk factor for allopurinol hypersensitivity syndrome: a proposed safe starting dose of allopurinol.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Case-Control Studies; Dose-Response Relationship, Drug; | 2012 |
Optimal management of chronic gout: attempting to render the (t)issues crystal-clear.
Topics: Allopurinol; Anti-Inflammatory Agents; Benzbromarone; Chronic Disease; Colchicine; Drug Hypersensiti | 2005 |
Oxipurinol therapy in allopurinol-allergic patients.
Topics: Aged; Allopurinol; Arthritis; Drug Hypersensitivity; Female; Gout; Humans; Oxypurinol; Pyrimidines; | 1983 |
Tubulointerstitial diseases.
Topics: Analgesics; Drug Hypersensitivity; Glomerular Filtration Rate; Humans; Hypercalcemia; Hypokalemia; I | 1980 |
[Allopurinol hypersensitivity. A possible cause of hepatitis and mucocutaneous eruptions in a patient undergoing antitubercular treatment].
Topics: Adult; Allopurinol; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; D | 1995 |
Successful desensitization of a fixed drug eruption caused by allopurinol.
Topics: Allopurinol; Desensitization, Immunologic; Drug Hypersensitivity; Gout Suppressants; Humans; Male; M | 1998 |
How should we treat tophaceous gout in patients with allopurinol hypersensitivity?
Topics: Adolescent; Adult; Aged; Allopurinol; Benzbromarone; Creatinine; Drug Hypersensitivity; Gout; Gout S | 1998 |
How should hyperuricemia be treated in a patient with allopurinol hypersensitivity?
Topics: Antimetabolites; Desensitization, Immunologic; Drug Hypersensitivity; Gout; Gout Suppressants; Human | 2001 |
[Hypersensitivity syndrome during therapy with allopurinol in asymptomatic hyperuricemia with a fatal outcome].
Topics: Aged; Aged, 80 and over; Allopurinol; Antimetabolites; Drug Hypersensitivity; Fatal Outcome; Female; | 2001 |
Massive hepatic necrosis in a patient receiving allopurinol.
Topics: Allopurinol; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Middle A | 1977 |
Allpurinol hypersensitivity syndrome: effects and treatment.
Topics: Adult; Aged; Allopurinol; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Syndrome; Uric A | 1978 |
[The side effects and complications in treatment with diuretic preparations. 2].
Topics: Diuretics; Drug Hypersensitivity; Humans; Hypercalcemia; Hyperkalemia; Hypocalcemia; Hypokalemia; Ma | 1992 |
The allopurinol hypersensitivity syndrome: its relation to plasma oxypurinol levels.
Topics: Aged; Aged, 80 and over; Allopurinol; Drug Hypersensitivity; Humans; Male; Metabolism, Inborn Errors | 1989 |
Allopurinol hypersensitivity in a patient with coexistent systemic lupus erythematosus and tophaceous gout.
Topics: Adult; Allopurinol; Arthrography; Drug Hypersensitivity; Fingers; Gout; Humans; Klinefelter Syndrome | 1988 |
The mackerel was in fact a red herring.
Topics: Allopurinol; Diagnostic Errors; Drug Hypersensitivity; Female; Food Hypersensitivity; Humans; Medica | 1986 |
Oral zinc therapy normalizes serum uric acid level in Wilson's disease patients.
Topics: Administration, Oral; Child; Drug Hypersensitivity; Female; Hepatolenticular Degeneration; Humans; L | 1986 |
[Acute renal failure after rifampicin (author's transl)].
Topics: Acute Kidney Injury; Adult; Anuria; Biopsy; Creatinine; Drug Hypersensitivity; Humans; Male; Middle | 1974 |
Immunologic reactivity in hyperuricemia.
Topics: Ampicillin; Drug Hypersensitivity; Female; Humans; Infectious Mononucleosis; Male; Uric Acid | 1972 |
Dysmetabolic and neurological complications in leukemia patients treated with L-asparaginase.
Topics: Asparaginase; Central Nervous System Diseases; Child; Clinical Enzyme Tests; Drug Hypersensitivity; | 1970 |