uric acid has been researched along with Akinetic-Rigid Variant of Huntington Disease in 10 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Huntington's disease is an autosomal dominant hereditary neurodegenerative disorder characterized by severe striatal cell loss." | 1.31 | Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine. ( Brundin, P; Castilho, RF; DiFiglia, M; Hansson, O; Petersén, A; Przedborski, S; Puschban, Z; Rice, M; Romero, N; Sapp, E; Sulzer, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Auinger, P | 1 |
| Kieburtz, K | 1 |
| McDermott, MP | 1 |
| Petersén, A | 1 |
| Hansson, O | 1 |
| Puschban, Z | 1 |
| Sapp, E | 1 |
| Romero, N | 1 |
| Castilho, RF | 1 |
| Sulzer, D | 1 |
| Rice, M | 1 |
| DiFiglia, M | 1 |
| Przedborski, S | 1 |
| Brundin, P | 1 |
| Insarova, NG | 1 |
| Korshunova, TS | 1 |
| Mzhel'skaia, TI | 1 |
| Borisova, TV | 1 |
| Reed, WB | 1 |
| Fish, CH | 1 |
| Lenoch, F | 1 |
| Kelley, WN | 1 |
| Kölle, G | 1 |
| Felix, JS | 1 |
| DeMars, R | 1 |
| Dawson, DM | 1 |
| Rautenstrauch, T | 1 |
1 review available for uric acid and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
[Lesh-Nyhan syndrome. Paralysis cerebralis hyperurinogenica].
Topics: Adolescent; Adult; Athetosis; Chemical Phenomena; Chemistry; Child; Compulsive Behavior; Female; Hum | 1970 |
9 other studies available for uric acid and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
The relationship between uric acid levels and Huntington's disease progression.
Topics: Adult; Aged; Biomarkers; Disease Progression; Female; Humans; Huntington Disease; Male; Middle Aged; | 2010 |
Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.
Topics: Aging; Animals; Ascorbic Acid; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dose-Respons | 2001 |
[Metabolic disorders in Huntington's chorea].
Topics: Adult; Bilirubin; Blood Glucose; Ceruloplasmin; Cholesterol; Copper; Female; Glucose Tolerance Test; | 1978 |
Hyperuricemia with self-mutilation and choreo-athetosis. Lesch-Nyhan syndrome.
Topics: Athetosis; Child; Humans; Huntington Disease; Intellectual Disability; Male; Self Mutilation; Uremia | 1966 |
Studies on the adenine phosphoribosyltransferase enzyme in human fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase.
Topics: Athetosis; Compulsive Behavior; Culture Techniques; Fibroblasts; Humans; Huntington Disease; Intelle | 1971 |
[Hyperuricemia and gout in childhood (Lesch-Nyhan syndrome)].
Topics: Adolescent; Athetosis; Brain; Child; Child, Preschool; Compulsive Behavior; Gout; Humans; Huntington | 1971 |
Detection of females heterozygous for the Lesch-Nyhan mutation by 8-azaguanine-resistant growth of cultured fibroblasts.
Topics: Athetosis; Autoradiography; Azaguanine; Biopsy; Compulsive Behavior; Culture Techniques; Female; Fib | 1971 |
Absence of guanine deaminase from cerebellum.
Topics: Aminohydrolases; Animals; Athetosis; Brain; Brain Chemistry; Cats; Caudate Nucleus; Cerebellum; Cere | 1971 |
[Lesch-Nyhan syndrome].
Topics: Allopurinol; Athetosis; Child; Compulsive Behavior; Diet Therapy; Humans; Huntington Disease; Intell | 1974 |