Page last updated: 2024-10-20

uric acid and Agnogenic Myeloid Metaplasia

uric acid has been researched along with Agnogenic Myeloid Metaplasia in 19 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Research Excerpts

ExcerptRelevanceReference
"Primary (PMF) and secondary myelofibrosis (SMF) are myeloproliferative neoplasms characterized by high cellular turnover and substantial risk of thrombosis and death."5.72Higher serum uric acid is associated with higher risks of thrombosis and death in patients with primary myelofibrosis. ( Galusic, D; Holik, H; Krecak, I; Kusec, R; Lucijanic, M; Moric Peric, M; Pejsa, V; Perisa, V; Sedinic, M; Stoos-Veic, T; Zekanovic, I, 2022)
" He was diagnosed as primary myelofibrosis and treated with interferon-α, together with urate acid-lowing therapy (febuxostat 60 mg once daily)."3.88[A case of gout secondary to primary myelofibrosis]. ( Hao, YJ; Ji, LL; Zhang, ZL, 2018)
"Primary (PMF) and secondary myelofibrosis (SMF) are myeloproliferative neoplasms characterized by high cellular turnover and substantial risk of thrombosis and death."1.72Higher serum uric acid is associated with higher risks of thrombosis and death in patients with primary myelofibrosis. ( Galusic, D; Holik, H; Krecak, I; Kusec, R; Lucijanic, M; Moric Peric, M; Pejsa, V; Perisa, V; Sedinic, M; Stoos-Veic, T; Zekanovic, I, 2022)
"Patients with myelofibrosis had echocardiographic evidence of PH more often than patients with other MPNs (p < 0."1.56Association of Disease Subtype and Duration with Echocardiographic Evidence of Pulmonary Hypertension in Myeloproliferative Neoplasm. ( Akgun-Cagliyan, G; Kaya, E; Kilic, O; Ozen, F; Senol, H; Yaylali, YT; Yilmaz, S, 2020)
"No identifiable cause of secondary myelofibrosis."1.26[Acute or subacute myelofibrosis]. ( Bernard, J; Brière, J; Brière, JF; Castro-Malaspina, H, 1976)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199016 (84.21)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.26)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Yaylali, YT1
Yilmaz, S1
Akgun-Cagliyan, G1
Kilic, O1
Kaya, E1
Senol, H1
Ozen, F1
Lucijanic, M1
Krecak, I1
Galusic, D1
Sedinic, M1
Holik, H1
Perisa, V1
Moric Peric, M1
Zekanovic, I1
Stoos-Veic, T1
Pejsa, V1
Kusec, R1
Ji, LL1
Hao, YJ1
Zhang, ZL1
LASTER, L1
MULLER, AF1
Rojer, RA1
Mulder, NH1
Nieweg, HO1
Brière, J1
Castro-Malaspina, H1
Brière, JF1
Bernard, J1
Klimova, NF1
Pilipas, VA1
Alvsaker, JO2
Kühböck, J1
Peskar, BM1
Vormittag, W1
Gilbert, HS1
Hunstein, W1
Hauswaldt, C1
Presant, CA1
Safdar, SH1
Ward, HP1
Block, MH1
Richter, R1
Hermanny, G1
Hofer, E1
Stobbe, H1
Lewis, SM1
Pettit, JE1
Tattersall, MH1
Pepys, MB1
Yü, TF1
Hooey, MA1
Crookston, JH1
Squires, AH1
Garrod, PR1
McSwiney, RR1
Bold, AM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Pulmonary Hypertension in Patients With Chronic Myeloproliferative Disorders at Sohag University Hospital[NCT04843475]150 participants (Anticipated)Observational2021-05-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for uric acid and Agnogenic Myeloid Metaplasia

ArticleYear
The spectrum of myeloproliferative disorders.
    The Medical clinics of North America, 1973, Volume: 57, Issue:2

    Topics: Blood Platelets; Cell Differentiation; Diagnosis, Differential; Hematocrit; Hematopoietic Stem Cells

1973
[Myelofibrosis (author's transl)].
    Klinische Wochenschrift, 1974, Apr-01, Volume: 52, Issue:7

    Topics: Antineoplastic Agents; Bone Marrow Examination; Folic Acid; Histamine; Humans; Hypertension, Portal;

1974
The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome.
    Medicine, 1971, Volume: 50, Issue:5

    Topics: Adrenal Cortex Hormones; Alkaline Phosphatase; Androgens; Anemia; Animals; Blood Cell Count; Blood C

1971

Other Studies

16 other studies available for uric acid and Agnogenic Myeloid Metaplasia

ArticleYear
Association of Disease Subtype and Duration with Echocardiographic Evidence of Pulmonary Hypertension in Myeloproliferative Neoplasm.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2020, Volume: 29, Issue:5

    Topics: Adult; Aged; Bone Marrow Neoplasms; Echocardiography; Female; Humans; Hypertension, Pulmonary; Male;

2020
Higher serum uric acid is associated with higher risks of thrombosis and death in patients with primary myelofibrosis.
    Wiener klinische Wochenschrift, 2022, Volume: 134, Issue:3-4

    Topics: Humans; Male; Primary Myelofibrosis; Prognosis; Retrospective Studies; Risk Factors; Thrombosis; Uri

2022
[A case of gout secondary to primary myelofibrosis].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2018, Dec-18, Volume: 50, Issue:6

    Topics: Arthritis, Gouty; Febuxostat; Gout; Gout Suppressants; Humans; Male; Middle Aged; Primary Myelofibro

2018
Uric acid production in a case of myeloid metaplasia associated with gouty arthritis, studied with N15 labeled glycine.
    The American journal of medicine, 1953, Volume: 15, Issue:6

    Topics: Arthritis, Gouty; Glycine; Gout; Humans; Metaplasia; Primary Myelofibrosis; Research; Uric Acid

1953
'Classic' and 'acute' myelofibrosis. A retrospective study.
    Acta haematologica, 1978, Volume: 60, Issue:2

    Topics: Acute Disease; Blood Cell Count; Blood Sedimentation; Bone Marrow; Hemoglobins; Humans; L-Lactate De

1978
[Acute or subacute myelofibrosis].
    Nouvelle revue francaise d'hematologie, 1976, Volume: 16, Issue:1

    Topics: Acute Disease; Adult; Aged; Alkaline Phosphatase; Bone Marrow Examination; Cell Survival; Erythrocyt

1976
[Characteristics of uric acid metabolism in myelofibrosis].
    Problemy gematologii i perelivaniia krovi, 1976, Volume: 21, Issue:7

    Topics: Adult; Aged; Humans; Kidney; Middle Aged; Primary Myelofibrosis; Uric Acid

1976
Uric acid in human plasma. V. Isolation and identification of plasma proteins interacting with urate.
    Scandinavian journal of clinical and laboratory investigation, 1966, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Aged; Alpha-Globulins; Blood Protein Electrophoresis; Chromatography, Gel; Chroma

1966
[A "myeloproliferative syndrome" of long duration (author's transl)].
    Medizinische Klinik, 1974, Mar-08, Volume: 69, Issue:10

    Topics: Aged; Arthritis; Bone Marrow; Chronic Disease; Diagnosis, Differential; Humans; Leukemia, Myeloid; M

1974
Oxymetholone in myelofibrosis and chronic lymphocytic leukemia.
    Archives of internal medicine, 1973, Volume: 132, Issue:2

    Topics: Aged; Anemia, Aplastic; Blood Cell Count; Blood Platelets; Blood Transfusion; Chemical and Drug Indu

1973
[Secondary hyperuricemia in hemoblastosis].
    Das Deutsche Gesundheitswesen, 1971, Nov-04, Volume: 26, Issue:45

    Topics: Blood Cell Count; Humans; Leukemia; Myeloproliferative Disorders; Nephrosis; Polycythemia Vera; Prim

1971
Myelosclerosis and paroxysmal nocturnal haemoglobinuria.
    Scandinavian journal of haematology, 1971, Volume: 8, Issue:6

    Topics: Adult; Alkaline Phosphatase; Bilirubin; Blood Proteins; Bone Marrow Examination; Chromium Isotopes;

1971
Uric acid in human plasma. IV. Investigations on the interactions between urate and the macromolecular fraction in plasma from healthy individuals and patients with diseases associated with hyperuricemia.
    Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Aged; Blood; Chemical Phenomena; Chemistry; Female; Gout; Hodgkin Disease; Humans

1965
Secondary gout associated with myeloproliferative diseases.
    Arthritis and rheumatism, 1965, Volume: 8, Issue:5

    Topics: Anemia, Hemolytic; Female; Gaucher Disease; Gout; Humans; Kidney Calculi; Leukemia, Myeloid; Male; N

1965
Myeloproliferative disease complicated by megaloblastic anemia and hyperuricemia.
    Canadian Medical Association journal, 1965, Oct-23, Volume: 93, Issue:17

    Topics: Anemia, Macrocytic; Blood; Blood Coagulation Disorders; Busulfan; Enzyme Therapy; Epistaxis; Female;

1965
Investigation of renal excretion of phosphate and urate.
    Clinical science, 1966, Volume: 31, Issue:1

    Topics: Adult; Gout; Humans; Middle Aged; Phosphates; Primary Myelofibrosis; Uric Acid; Urinary Calculi

1966