uric acid has been researched along with Adverse Drug Event in 26 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To analyze the efficacy and safety of benzbromarone in elderly hypertensive patients with hyperuricemia." | 7.91 | Clinical efficacy and safety of benzbromarone in elderly hypertensive patients with hyperuricemia. ( Gao, H, 2019) |
| "Hyperuricemia is frequently reported in adults, but there are few data for the pediatric population." | 5.42 | Is Hyperuricemia Overlooked when Treating Pediatric Tuberculosis Patients with Pyrazinamide? ( Aslan, AT; Budakoğlu, I; Şişmanlar, T, 2015) |
| "A number of pharmacological agents can induce hyperuricaemia, and sometimes gout, usually by interfering with the renal tubular excretion of urate but also in some instances by increasing the formation of uric acid." | 4.78 | Drug-induced gout. ( Scott, JT, 1991) |
| "To analyze the efficacy and safety of benzbromarone in elderly hypertensive patients with hyperuricemia." | 3.91 | Clinical efficacy and safety of benzbromarone in elderly hypertensive patients with hyperuricemia. ( Gao, H, 2019) |
| " The control group received neither acetaminophen nor the extract while the last group received only a toxic dose of acetaminophen." | 1.72 | Protective Effect of the Hydroalcoholic Extract of Pelargonium Graveolens L. on Rats with Acetaminophen- Induced Nephrotoxicity. ( Akbarpour, B; Asmarian, S; Gholyaf, M; Mohammadi, F, 2022) |
| "In tuberculosis (TB) treatment, adverse drug reactions (ADRs) can interrupt treatment and decrease the quality of life (QoL)." | 1.72 | Incidence and outcomes of adverse drug reactions to first-line anti-tuberculosis drugs and their effects on the quality of life: A multicenter prospective cohort study. ( Ban, GY; Choi, H; Choi, JH; Hong, JY; Hwang, YI; Hyun, IG; Jang, SH; Kim, JH; Ko, Y; Lee, CY; Lee, MG; Park, HA; Shin, TR; Sim, YS, 2022) |
| "Hyperuricemia is frequently reported in adults, but there are few data for the pediatric population." | 1.42 | Is Hyperuricemia Overlooked when Treating Pediatric Tuberculosis Patients with Pyrazinamide? ( Aslan, AT; Budakoğlu, I; Şişmanlar, T, 2015) |
| "Rasburicase (recombinant urate oxidase) is a uricolytic agent which has been developed for the prevention and treatment of chemotherapy-induced hyperuricaemia at a dosage of 0." | 1.31 | Rasburicase. ( Easton, J; Jarvis, B; Noble, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Gholyaf, M | 2 |
| Asmarian, S | 1 |
| Akbarpour, B | 1 |
| Mohammadi, F | 1 |
| Choi, H | 2 |
| Park, HA | 1 |
| Hyun, IG | 1 |
| Kim, JH | 1 |
| Hwang, YI | 1 |
| Jang, SH | 1 |
| Sim, YS | 1 |
| Shin, TR | 1 |
| Ko, Y | 1 |
| Ban, GY | 1 |
| Hong, JY | 1 |
| Lee, CY | 1 |
| Lee, MG | 1 |
| Choi, JH | 1 |
| Gao, H | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
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| Naveed, A | 1 |
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| Siddique, AB | 1 |
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| Mushtaq, Z | 1 |
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| Ilyas, S | 1 |
| Bibi, I | 1 |
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| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
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| Okunade, KS | 1 |
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| Rabiu, KA | 1 |
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| Xu, C | 2 |
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| Dong, X | 1 |
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| Dong, XR | 1 |
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| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
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| Li, Y | 5 |
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| Rojas, A | 1 |
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| Theobald, A | 1 |
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| Li, J | 7 |
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| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
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| Hou, J | 1 |
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| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 2 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
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| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
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| Zhang, Y | 4 |
| Wu, X | 1 |
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| Huang, H | 1 |
| Wei, Y | 2 |
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| Na, KJ | 1 |
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| Kim, YH | 1 |
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| Jung, YJ | 1 |
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| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
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| Logotheti, S | 1 |
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| Liang, C | 1 |
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| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
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| Ma, WY | 1 |
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| Patsourakos, NG | 1 |
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| Kotidis, A | 1 |
| Kalantzi, KI | 1 |
| Tsoumani, ME | 1 |
| Anastasiadis, F | 1 |
| Andronikos, P | 1 |
| Aslanidou, T | 1 |
| Efraimidis, P | 1 |
| Georgiopoulos, A | 1 |
| Gerakiou, K | 1 |
| Grigoriadou-Skouta, E | 1 |
| Grigoropoulos, P | 1 |
| Hatzopoulos, D | 1 |
| Kartalis, A | 1 |
| Lyras, A | 1 |
| Markatos, G | 1 |
| Mikrogeorgiou, A | 1 |
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| Orkopoulos, A | 1 |
| Pavlidis, P | 1 |
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| Chen, W | 2 |
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| Sugimura, H | 2 |
| Stefan-van Staden, RI | 1 |
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| Iwashita, Y | 1 |
| Szodorai, R | 1 |
| Szederjesi, J | 1 |
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| Validad, MH | 1 |
| Langroudi, FH | 1 |
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| Hassanpour, K | 1 |
| Kurup, SP | 1 |
| Mets-Halgrimson, R | 1 |
| Yoon, H | 1 |
| Zeid, JL | 1 |
| Mets, MB | 1 |
| Rahmani, B | 1 |
| Araujo-Castillo, RV | 1 |
| Culquichicón, C | 1 |
| Solis Condor, R | 1 |
| Efendi, F | 1 |
| Sebayang, SK | 1 |
| Astutik, E | 1 |
| Hadisuyatmana, S | 1 |
| Has, EMM | 1 |
| Kuswanto, H | 1 |
| Foroutan, T | 1 |
| Ahmadi, F | 1 |
| Moayer, F | 1 |
| Khalvati, S | 1 |
| Zhang, Q | 2 |
| Lyu, Y | 1 |
| Huang, J | 1 |
| Yu, N | 1 |
| Wen, Z | 1 |
| Hou, H | 1 |
| Zhao, T | 1 |
| Gupta, A | 2 |
| Khosla, N | 1 |
| Govindasamy, V | 1 |
| Saini, A | 1 |
| Annapurna, K | 1 |
| Dhakate, SR | 1 |
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| Chandgude, AL | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Investigation of Aging Men With Renal Stones: The Role of Bone Demineralization (Metabolic and Hormonal Assessment)[NCT01246531] | 42 participants (Actual) | Observational | 2008-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for uric acid and Adverse Drug Event
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy.
Topics: Aged; Chronic Disease; Clinical Trials, Phase III as Topic; Cluster Analysis; Dose-Response Relation | 2014 |
Medical management of renal stone disease.
Topics: Acidosis; Case Management; Comorbidity; Diet Therapy; Drug-Related Side Effects and Adverse Reaction | 2011 |
[Molecular mechanism in biological transport in the kidney: Organic cation/anion transporters].
Topics: Animals; Biological Transport; Carnitine; Carrier Proteins; Drug-Related Side Effects and Adverse Re | 2006 |
Pathophysiology and clinical aspects of urinary lithiasis.
Topics: Calcium; Cystine; Cystinuria; Drug-Related Side Effects and Adverse Reactions; Humans; Hypercalciuri | 2007 |
[Physiopathological aspects of secondary hyperuricemia].
Topics: Acute Disease; Coronary Disease; Drug-Related Side Effects and Adverse Reactions; Fructose; Glycogen | 1991 |
Drug-induced gout.
Topics: Cyclosporins; Cytotoxins; Diuretics; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Et | 1991 |
2 trials available for uric acid and Adverse Drug Event
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout.
Topics: Aged; Allopurinol; Benzbromarone; Confidence Intervals; Dose-Response Relationship, Drug; Drug Admin | 2009 |
18 other studies available for uric acid and Adverse Drug Event
| Article | Year |
|---|---|
Protective Effect of the Hydroalcoholic Extract of Pelargonium Graveolens L. on Rats with Acetaminophen- Induced Nephrotoxicity.
Topics: Acetaminophen; Animals; Creatinine; Drug-Related Side Effects and Adverse Reactions; Mice; Pelargoni | 2022 |
Incidence and outcomes of adverse drug reactions to first-line anti-tuberculosis drugs and their effects on the quality of life: A multicenter prospective cohort study.
Topics: Adult; Aged; Anorexia; Antitubercular Agents; Drug-Related Side Effects and Adverse Reactions; Femal | 2022 |
Clinical efficacy and safety of benzbromarone in elderly hypertensive patients with hyperuricemia.
Topics: Aged; Benzbromarone; Blood Pressure; Drug-Related Side Effects and Adverse Reactions; Female; Humans | 2019 |
Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity.
Topics: Adenine; Amino Acids; Animals; Antiviral Agents; Cell Line; Cercopithecidae; Dogs; Drug-Related Side | 2018 |
Factors influencing Urate Lowering Therapies prescription for asymptomatic hyperuricemia by general practitioners: a qualitative study.
Topics: Adult; Drug-Related Side Effects and Adverse Reactions; Family Practice; Female; General Practitione | 2019 |
Is Hyperuricemia Overlooked when Treating Pediatric Tuberculosis Patients with Pyrazinamide?
Topics: Adolescent; Allopurinol; Antitubercular Agents; Child; Child, Preschool; Drug Administration Schedul | 2015 |
Medication trials in an imperfect world: gout and Parkinson's disease.
Topics: Antiparkinson Agents; Cardiovascular Diseases; Clinical Trials as Topic; Disease Progression; Drug-R | 2009 |
Management of the stone former.
Topics: Allopurinol; Calcium; Cellulose; Cystinuria; Diet; Drug-Related Side Effects and Adverse Reactions; | 1984 |
Piroxicam (Feldene) predisposes to chemotherapy-induced acute uric acid nephropathy.
Topics: Acute Disease; Aged; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney Diseases; Male; | 1984 |
Rasburicase.
Topics: Adolescent; Child; Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Humans | 2001 |
[Hyperuricemia and gout--diagnosis].
Topics: Adenine; Adult; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Go | 2002 |
[Treatment of oncologic emergencies after cytostatic therapy].
Topics: Allopurinol; Blood Platelets; Blood Transfusion; Breast Neoplasms; Drug-Related Side Effects and Adv | 1979 |
[Hyperuricemia due to therapeutic measures].
Topics: Antihypertensive Agents; Antineoplastic Agents; Antiparkinson Agents; Antitubercular Agents; Drug-Re | 1977 |
Acute tumour lysis syndrome with extreme metabolic abnormalities.
Topics: Adult; Drug-Related Side Effects and Adverse Reactions; Humans; Hypercalcemia; Hyperkalemia; Hypocal | 1987 |
[Serum potassium, creatinine and uric acid in 331 institutionalized elderly: pharmacologic considerations].
Topics: Aged; Creatinine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Institutionalizat | 1986 |
Pharmacogenetics.
Topics: Abnormalities, Drug-Induced; Allopurinol; Barbiturates; Chromosome Aberrations; Drug-Related Side Ef | 1974 |
[The effect of pharmaca-in vivo and in vitro-on a new enzymatic colorimetric uric acid test (author's transl)].
Topics: Clinical Enzyme Tests; Colorimetry; Drug-Related Side Effects and Adverse Reactions; Humans; In Vitr | 1974 |
[Clinical significance of hyperuricemia in the hospitalized population].
Topics: Adolescent; Adult; Aged; Drug-Related Side Effects and Adverse Reactions; Hospitalization; Humans; M | 1971 |