uric acid has been researched along with Acute Myelogenous Leukemia in 42 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the ability of serum uric acid (SUA) to predict laboratory tumor lysis syndrome (LTLS) and compared it to common laboratory variables, cytogenetic profiles, tumor markers and prediction models in acute myeloid leukemia patients." | 7.81 | Uric acid and the prediction models of tumor lysis syndrome in AML. ( Ejaz, AA; Hsu, JW; Johnson, RJ; Mohandas, R; Pourafshar, N; Smallwood, BA, 2015) |
| "We investigated the ability of serum uric acid (SUA) to predict laboratory tumor lysis syndrome (LTLS) and compared it to common laboratory variables, cytogenetic profiles, tumor markers and prediction models in acute myeloid leukemia patients." | 3.81 | Uric acid and the prediction models of tumor lysis syndrome in AML. ( Ejaz, AA; Hsu, JW; Johnson, RJ; Mohandas, R; Pourafshar, N; Smallwood, BA, 2015) |
| "Uric acid (UA) is a strong immunological danger signal." | 1.46 | Uric acid as a novel biomarker for bone-marrow function and incipient hematopoietic reconstitution after aplasia in patients with hematologic malignancies. ( Bethge, WA; Eyb, V; Faul, C; Haen, SP; Heni, M; Kanz, L; Löffler, MW; Mirza, N; Naumann, A; Peter, A; Rammensee, HG; Vogel, W, 2017) |
| "In the first week, infection contributed to 71% of the deaths and pulmonary hemorrhage associated with diffuse alveolar damage contributed to 44%; the incidence of infection rose while the incidence of hemorrhage decreased during weeks 2 to 4." | 1.31 | Reducing mortality associated with immediate treatment complications of adult leukemias. ( Estey, E, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (71.43) | 18.7374 |
| 1990's | 1 (2.38) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 7 (16.67) | 24.3611 |
| 2020's | 3 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Majumdar, S | 1 |
| Sharma, N | 1 |
| Sengar, M | 1 |
| Thorat, J | 1 |
| Nayak, L | 1 |
| Bonda, A | 1 |
| Bagal, B | 1 |
| Rajendra, A | 1 |
| Sethi, A | 1 |
| Jain, H | 1 |
| Cheng, FM | 1 |
| Tien, JZ | 1 |
| Chen, TT | 1 |
| Yeh, SP | 1 |
| Lin, CC | 1 |
| Diao, S | 1 |
| Nichols, ED | 1 |
| DiNardo, C | 1 |
| Konopleva, M | 1 |
| Ning, J | 1 |
| Qiao, W | 1 |
| Maiti, A | 1 |
| DiPippo, AJ | 1 |
| Cantor, JR | 1 |
| Abu-Remaileh, M | 1 |
| Kanarek, N | 1 |
| Freinkman, E | 1 |
| Gao, X | 1 |
| Louissaint, A | 1 |
| Lewis, CA | 1 |
| Sabatini, DM | 1 |
| Yamauchi, T | 1 |
| Negoro, E | 1 |
| Lee, S | 1 |
| Takai, M | 1 |
| Matsuda, Y | 1 |
| Takagi, K | 1 |
| Kishi, S | 1 |
| Tai, K | 1 |
| Hosono, N | 1 |
| Tasaki, T | 1 |
| Ikegaya, S | 1 |
| Inai, K | 1 |
| Yoshida, A | 1 |
| Urasaki, Y | 1 |
| Iwasaki, H | 1 |
| Ueda, T | 1 |
| Kishimoto, K | 1 |
| Kobayashi, R | 2 |
| Ichikawa, M | 2 |
| Sano, H | 1 |
| Suzuki, D | 2 |
| Yasuda, K | 1 |
| Iguchi, A | 1 |
| Kobayashi, K | 1 |
| Ejaz, AA | 2 |
| Pourafshar, N | 1 |
| Mohandas, R | 1 |
| Smallwood, BA | 1 |
| Johnson, RJ | 2 |
| Hsu, JW | 1 |
| Koratala, A | 1 |
| Singhania, G | 1 |
| Alquadan, KF | 1 |
| Shimada, M | 1 |
| Haen, SP | 1 |
| Eyb, V | 1 |
| Mirza, N | 1 |
| Naumann, A | 1 |
| Peter, A | 1 |
| Löffler, MW | 1 |
| Faul, C | 1 |
| Vogel, W | 1 |
| Bethge, WA | 1 |
| Rammensee, HG | 1 |
| Kanz, L | 1 |
| Heni, M | 1 |
| Nakajima, M | 1 |
| Inamoto, J | 1 |
| Cho, Y | 1 |
| Kaneda, M | 1 |
| Yoshida, M | 1 |
| Ariga, T | 1 |
| Balcar-Boroń, A | 1 |
| Czerwionka-Szaflarska, M | 1 |
| Słowik, J | 1 |
| Wysocki, M | 1 |
| Hoffmann, A | 1 |
| Kwiatkowska, D | 1 |
| Langner, W | 1 |
| Rico Lenza, H | 1 |
| Díaz Mediavilla, J | 1 |
| Hernández Díaz, ER | 1 |
| Jara Orellana, N | 1 |
| Bordiu Obanza, E | 1 |
| Charro Salgado, A | 1 |
| Espinós Pérez, D | 1 |
| Chevion, S | 1 |
| Or, R | 1 |
| Berry, EM | 1 |
| Estey, E | 1 |
| Vilpo, JA | 1 |
| Levanto, A | 1 |
| Jones, WA | 1 |
| Mir, MA | 2 |
| Sonoda, Y | 1 |
| Sawai, K | 1 |
| Misawa, S | 1 |
| Takino, T | 1 |
| Abe, T | 1 |
| Becher, R | 1 |
| Firusian, N | 1 |
| Greene, T | 1 |
| Orchard, PJ | 1 |
| Moffet, HL | 1 |
| Hafez, GR | 1 |
| Sondel, PM | 1 |
| Simonson, GM | 1 |
| Matheke, ML | 1 |
| Kessler, G | 1 |
| Chan, KM | 1 |
| Rainer, H | 1 |
| Lugscheider, R | 1 |
| Bauer, K | 1 |
| Moser, K | 1 |
| Ledvina, M | 1 |
| Lampkin, B | 1 |
| McWilliams, NB | 1 |
| Mauer, AM | 1 |
| Levi, JA | 1 |
| Speden, JB | 1 |
| Vincent, PC | 1 |
| Gunz, FW | 1 |
| Arfi, S | 1 |
| Baglin, A | 1 |
| Alterescu, R | 1 |
| Goguel, A | 1 |
| Fendler, JP | 1 |
| Fritel, D | 1 |
| Vysotskaia, TA | 1 |
| Kisliak, NS | 1 |
| Lenskaia, RV | 1 |
| Morozova, EA | 1 |
| Samochatova, EV | 1 |
| Leonova, LV | 1 |
| Delamore, IW | 1 |
| Schmidt, CG | 1 |
| Gallmeier, WM | 1 |
| Nissen, NI | 1 |
| Dano, K | 1 |
| Vogler, WR | 1 |
| Brown, CH | 1 |
| Stashick, E | 1 |
| Carbone, PP | 1 |
| Marmont, AM | 1 |
| Damasio, EE | 1 |
| Rundles, RW | 1 |
| Oettgen, HF | 1 |
| Old, LJ | 1 |
| Boyse, EA | 1 |
| Campbell, HA | 1 |
| Philips, FS | 1 |
| Clarkson, BD | 1 |
| Tallal, L | 1 |
| Leeper, RD | 1 |
| Schwartz, MK | 1 |
| Kim, JH | 1 |
| Schiffer, LM | 1 |
| Atkins, HL | 1 |
| Chanana, AD | 1 |
| Cronkite, EP | 1 |
| Greenberg, ML | 1 |
| Stryckmans, PA | 1 |
| Jakubowska, D | 1 |
| Ziólkiewicz, Z | 1 |
| Handa, SP | 1 |
| Martin, DJ | 1 |
| Jaffe, N | 1 |
| Storti, E | 1 |
| Quaglino, D | 1 |
3 reviews available for uric acid and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
[Biochemical findings in body fluids in leukemia patients. Changes in the urine].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Amino Acids; Ammonia; Creatine; Creatinine; Electrolytes; | 1967 |
Treatment of acute leukemia.
Topics: Asparaginase; Bacterial Infections; Central Nervous System Diseases; Child; Child, Preschool; Cyclop | 1972 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; | 1970 |
3 trials available for uric acid and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
A phase II study to evaluate the efficacy of low-dose rasburicase (1.5mg) in adolescent and adult acute leukemia and high-grade lymphomas with tumor lysis syndrome.
Topics: Adolescent; Adult; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Tumor Lysis Syndrome; Ur | 2023 |
Clinical trials of 1-beta-D-arabinofuranosyl cytosine and 1,3-bis-(2-chloroethyl)-1-nitrosourea combination in metastatic cancer and acute leukemia.
Topics: Age Factors; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Clinical Trials as Topic; Cytar | 1971 |
Clinical efficacy and lack of toxicity of allopurinol (NSC-1390) given intravenously.
Topics: Administration, Oral; Adolescent; Adult; Alkaline Phosphatase; Allopurinol; Blood Urea Nitrogen; Chi | 1970 |
36 other studies available for uric acid and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Venetoclax plus cytochrome P450 inhibitors without ramp-up strategy led to low risk of tumor lysis syndrome in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitid | 2020 |
Incidence of tumor lysis syndrome in patients with acute myeloid leukemia undergoing low-intensity induction with venetoclax.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, | 2021 |
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Topics: Aged; Animals; Cell Culture Techniques; Cell Line, Tumor; Culture Media; Fluorouracil; Glucose; Huma | 2017 |
A high serum uric acid level is associated with poor prognosis in patients with acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Female; Humans; L-Lactate Dehydrogena | 2013 |
Risk factors for tumor lysis syndrome in childhood acute myeloid leukemia treated with a uniform protocol without rasburicase prophylaxis.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Child; Child, Pres | 2015 |
Uric acid and the prediction models of tumor lysis syndrome in AML.
Topics: Acute Kidney Injury; Antineoplastic Agents; Biomarkers; Female; Humans; Incidence; Leukemia, Myeloid | 2015 |
Serum Uric Acid Exhibits Inverse Relationship with Estimated Glomerular Filtration Rate.
Topics: Acute Kidney Injury; Cohort Studies; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney | 2016 |
Uric acid as a novel biomarker for bone-marrow function and incipient hematopoietic reconstitution after aplasia in patients with hematologic malignancies.
Topics: Adult; Aged; Anemia; Biomarkers, Tumor; Blood Cell Count; Bone Marrow; Female; Graft Survival; Hemat | 2017 |
Higher urinary excretion of inorganic phosphate during early induction chemotherapy predicts a good prognosis in childhood acute leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Child; Child, Preschool; Fem | 2011 |
[Serum iron and copper concentration in children with acute leukemia].
Topics: Adolescent; Child; Child, Preschool; Copper; Female; Humans; Infant; Iron; Leukemia, Lymphoid; Leuke | 1983 |
[Imbalance of hormones regulating the phosphocalcium metabolism in myeloid leukemia].
Topics: Adult; Calcitonin; Calcium; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middl | 1984 |
The antioxidant status of patients subjected to total body irradiation.
Topics: Adolescent; Adult; Anemia, Aplastic; Antioxidants; Ascorbic Acid; Bone Marrow Transplantation; Child | 1999 |
Reducing mortality associated with immediate treatment complications of adult leukemias.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cause of Death; Humans; Infection | 2001 |
Effect of granulocytic chalone on acute myeloid leukaemia in man. A follow-up study.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Blood Platelets; Blood Sedimentation; Bone Marrow | 1977 |
Renal excretion of uric acid and its relation to relapse and remission in acute myeloid leukaemia.
Topics: Adolescent; Adult; Aged; Allopurinol; Creatinine; Female; Homeostasis; Humans; Kidney; Kidney Tubule | 1977 |
[Uric acid nephropathy in a case of AML (author's transl)].
Topics: Acute Kidney Injury; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Renal Dial | 1977 |
[Acute hyperuricemia as an oncological emergency].
Topics: Adult; Allopurinol; Daunorubicin; Drug Therapy, Combination; Humans; L-Lactate Dehydrogenase; Leukem | 1978 |
Current therapy for acute leukemia in childhood.
Topics: Antineoplastic Agents; Bone Marrow Diseases; Child; Humans; Leukemia; Leukemia, Myeloid, Acute; Pati | 1976 |
Pseudomonas sepsis simulating acute promyelocytic leukemia.
Topics: Bone Marrow Examination; Hemoglobins; Hepatomegaly; Humans; Infant; Leukemia, Myeloid, Acute; Leukoc | 1988 |
Caring for patients with acute myelocytic leukemia.
Topics: Bone Marrow; Daunorubicin; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged | 1988 |
Interference of the chemotherapeutic agent etoposide with the direct phosphotungstic acid method for uric acid.
Topics: Etoposide; False Positive Reactions; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Phosphot | 1987 |
[Reverse transcriptase activities in human plasma of malignant states (author's transl)].
Topics: Breast Neoplasms; Carcinoma; Chromatography, Affinity; DNA; Female; Humans; Leukemia, Myeloid, Acute | 1974 |
Studies on muramidase in hematologic disorders. I. Serum muramidase and serum lactic dehydrogenase in leukemia.
Topics: Adult; Female; Hematologic Diseases; Humans; L-Lactate Dehydrogenase; Leukemia; Leukemia, Lymphoid; | 1973 |
[Acute kidney failure in acute leukemia].
Topics: Acute Kidney Injury; Adult; Aged; Blood Cell Count; Female; Furosemide; Humans; Leukemia; Leukemia, | 1973 |
[Certain cases of acute leukemia in children with hyperleukocytosis in the peripheral blood and increased risk of development of uric acid nephropathy].
Topics: Acute Kidney Injury; Adolescent; Female; Histocytochemistry; Humans; Kidney Diseases; Leukemia, Lymp | 1974 |
[Uric acid nephropathy with uremia during treatment of acute leukemia in children].
Topics: Acute Kidney Injury; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Humans; Kidney; Leu | 1974 |
Hypouricaemia and proximal renal tubular dysfunction in acute myeloid leukaemia.
Topics: Amino Acids; Calcium; Creatinine; Cytarabine; Daunorubicin; Female; Humans; Hydrogen-Ion Concentrati | 1974 |
[On the enzyme therapy of leukemias].
Topics: Adolescent; Adult; Aged; Asparaginase; Asparagine; Blood Cell Count; Blood Sedimentation; Enzymes; F | 1968 |
Some clinical observations on the treatment with L-asparaginase of the acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Asparaginase; Blood Chemical Analysis; Blood Platelets; Body | 1970 |
Metabolic effects of allopurinol and allo-xanthine.
Topics: Adult; Allopurinol; Drug Tolerance; Enzyme Therapy; Female; Gout; Humans; Leukemia, Myeloid, Acute; | 1966 |
Inhibition of leukemias in man by L-asparaginase.
Topics: Adolescent; Adult; Asparaginase; Blood Platelets; Body Temperature; Bone Marrow Examination; Child; | 1967 |
Extracorporeal irradiation of blood (ECIB) in man. II. Treatment of acute myelocytic leukemia.
Topics: Acute Disease; Adult; Aged; Blood Cell Count; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, | 1968 |
[Hyperuricemia with arthritis symptoms in the course of acute myeloid leukemia].
Topics: Gout; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Uric Acid | 1967 |
Acute renal railure in association with hyperuricemia: its recovery with ethacrynic acid.
Topics: Acute Kidney Injury; Bicarbonates; Ethacrynic Acid; Female; Humans; Infusions, Parenteral; Leukemia, | 1971 |
Prolonged nephrogram due to hyperuricaemia.
Topics: Female; Humans; Kidney; Kidney Diseases; Leukemia, Myeloid, Acute; Metabolic Diseases; Spleen; Uric | 1971 |
Dysmetabolic and neurological complications in leukemia patients treated with L-asparaginase.
Topics: Asparaginase; Central Nervous System Diseases; Child; Clinical Enzyme Tests; Drug Hypersensitivity; | 1970 |