uric acid and ALS - Amyotrophic Lateral Sclerosis

uric acid has been researched along with ALS - Amyotrophic Lateral Sclerosis in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (11.11)	18.7374
1990's	2 (5.56)	18.2507
2000's	3 (8.33)	29.6817
2010's	16 (44.44)	24.3611
2020's	11 (30.56)	2.80

Authors

Authors	Studies
Choi, YC; Han, HJ; Kim, SM; Kim, SW; Shin, HY	1
Basile, MS; Bramanti, P; Mazzon, E	1
Kano, O; Nagano, Y; Nelson, S; Takahashi, F; Ushirogawa, Y; Yoneoka, T	2
Cooper-Knock, J; Julian, TH; Motsi, GK; Şanlı, BA; Shen, E; Whittaker, KJ	1
Berry, JD; Beukenhorst, AL; Chan, J; Chase, M; Connolly, M; Cudkowicz, ME; Dagostino, D; Ferment, V; Gelevski, D; Hall, M; Lieberman, C; Locatelli, E; Macklin, EA; Manousakis, G; Nicholson, K; Onnela, JP; Ostrow, J; Paganoni, S; Pothier, L; Randall, R; Schwarzschild, MA; Sherman, AV; Steinhart, E; Walk, D; Walker, DG; Walker, J; Wills, AM; Yu, H	1
Bai, J; Feng, F; He, Z; Huang, X; Li, M; Wang, H; Wang, J; Yang, F; Yu, W; Zhang, X	1
Areprintseva, DK; Kutlubaev, MA; Pervushina, EV	1
Fan, DS; Fu, JY; He, J; Zhao, YN	1
Andrews, H; Barohn, RJ; Bedlack, RS; Factor-Litvak, P; Fernandes, JAM; Garofalo, DC; Gilmore, M; Heitzman, D; Hupf, J; Kasarskis, EJ; Katz, JS; Lomen-Hoerth, C; Mitsumoto, H; Mozaffar, T; Nations, SP; Oskarsson, B; Santella, RM; Sorenson, EJ; Swenson, AJ	1
Furukawa, T; Haji, S; Izumi, Y; Kaji, R; Murakami, N; Osaki, Y; Sako, W	1
Atassi, N; Berry, J; Chan, J; Cudkowicz, M; Nicholson, K; Paganoni, S; Schoenfeld, D; Sherman, A; Shui, A	1
Ascherio, A; Bjornevik, K; Kolonel, LN; Le Marchand, L; Manson, JE; McCullough, ML; O'Reilly, ÉJ; Schwarzschild, MA	1
Chen, X; Hao, J; Ke, Y; Lu, L; Lu, N; Zhang, F; Zhang, Q	1
Bakshi, R; Chen, X; Granucci, E; Mueller, KA; Paganoni, S; Sadri-Vakili, G; Schwarzschild, MA; Xu, Y	1
Mitsumoto, H; Saito, T	1
Feng, H; Jiang, H; Liang, W; Wang, S; Wang, T; Wang, X; Wang, Y; Yang, Y; Zhang, C	1
Cao, B; Chen, X; Chen, Y; Hou, Y; Liu, H; Ou, R; Shang, H; Wei, QQ; Yuan, X; Zhang, L	1
Cao, B; Chen, X; Guo, X; Huang, R; Ou, R; Shang, H; Song, W; Wei, Q; Zheng, Z	1
Abraham, A; Drory, VE	1
Miyazaki, Y; Nagase, M; Yamamoto, Y; Yoshino, H	1
Duan, Y; Fan, D	1
Ascherio, A; Cudkowicz, ME; Johns, DR; Leitner, M; Liu, D; O'Reilly, ÉJ; Paganoni, S; Schwarzschild, MA	1
Artamonov, I; Berliner, S; Drory, VE; Ish-Shalom, M; Keizman, D; Maimon, N; Nefussy, B; Tsehori, J; Vered, Y	1
Ikeda, K; Iwasaki, Y; Kawabe, K	1
Blagojević, D; Jones, DR; Nikolić-Kokić, A; Spasić, MB; Spasojević, I; Stević, Z	1
Capozzo, R; D'Errico, E; Leo, A; Logroscino, G; Simone, IL; Tortelli, R; Zoccolella, S	1
Cudkowicz, ME; Jaffa, M; Paganoni, S; Quiroz Zárate, A; Wills, AM; Yu, H; Zhang, M	1
Hirayama, T; Ikeda, K; Iwasaki, Y; Kawabe, K; Takazawa, T	1
Okamoto, K; Sohmiya, M; Suzuki, Y; Tanaka, M; Tanino, Y; Yamamoto, Y	1
Chen, LL; Fridovich, I; Hallewell, RA; Liochev, SI	2
Mallette, LE; Patten, BM	1
Bunina, TL; Khondkarian, OA; Korshunova, TS; Larskiĭ, EG	1
Fareed, GC; Tyler, HR	1

Reviews

5 review(s) available for uric acid and ALS - Amyotrophic Lateral Sclerosis

Article	Year
Inosine in Neurodegenerative Diseases: From the Bench to the Bedside. Molecules (Basel, Switzerland), 2022, Jul-21, Volume: 27, Issue:14 Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Antioxidants; Humans; Inosine; Multiple Sclerosis; Neurodegenerative Diseases; Parkinson Disease; Quality of Life; Uric Acid	2022
The value of serum uric acid as a prognostic biomarker in amyotrophic lateral sclerosis: Evidence from a meta-analysis. Clinical neurology and neurosurgery, 2021, Volume: 203 Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Humans; Prognosis; Sensitivity and Specificity; Uric Acid	2021
Serum uric acid levels in patients with amyotrophic lateral sclerosis: a meta-analysis. Scientific reports, 2018, 01-18, Volume: 8, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Case-Control Studies; Cause of Death; Humans; Prognosis; Publication Bias; Uric Acid	2018
[A prognostic biomarker in amyotrophic lateral sclerosis]. Rinsho shinkeigaku = Clinical neurology, 2018, Dec-21, Volume: 58, Issue:12 Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Brain; Creatinine; Disease Progression; Electric Impedance; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Myography; Neurofilament Proteins; Neuroimaging; Positron-Emission Tomography; Prognosis; Transcranial Magnetic Stimulation; Uric Acid	2018
Influence of serum uric acid levels on prognosis and survival in amyotrophic lateral sclerosis: a meta-analysis. Journal of neurology, 2014, Volume: 261, Issue:6 Topics: Amyotrophic Lateral Sclerosis; Female; Humans; Male; Prognosis; PubMed; Sex Factors; Uric Acid	2014

Trials

5 trial(s) available for uric acid and ALS - Amyotrophic Lateral Sclerosis

Article	Year
Associations between urate levels and amyotrophic lateral sclerosis functional score with edaravone treatment: Post hoc analysis of studies MCI186-16, MCI186-17, and MCI186-19. Muscle & nerve, 2022, Volume: 66, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Clinical Trials, Phase III as Topic; Disease Progression; Double-Blind Method; Edaravone; Free Radical Scavengers; Humans; Uric Acid	2022
Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis. Muscle & nerve, 2023, Volume: 67, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Double-Blind Method; Humans; Inosine; Retrospective Studies; Uric Acid	2023
Increased oxidative stress in patients with amyotrophic lateral sclerosis and the effect of edaravone administration. Redox report : communications in free radical research, 2016, Volume: 21, Issue:3 Topics: Aged; Amyotrophic Lateral Sclerosis; Antipyrine; Biomarkers; Edaravone; Fatty Acids, Nonesterified; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Ubiquinone; Uric Acid	2016
Serum urate at trial entry and ALS progression in EMPOWER. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2017, Volume: 18, Issue:1-2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Antioxidants; Benzothiazoles; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; International Cooperation; Male; Middle Aged; Pramipexole; Sex Factors; Survival Analysis; Uric Acid; Young Adult	2017
The use of isoprinosine in patients with amyotrophic lateral sclerosis. Neurology, 1971, Volume: 21, Issue:9 Topics: Acetamides; Adult; Aged; Amino Alcohols; Amyotrophic Lateral Sclerosis; Benzoates; Clinical Trials as Topic; Creatine Kinase; Female; Follow-Up Studies; Humans; Lung; Male; Middle Aged; Nucleosides; Placebos; Speech; Uric Acid	1971

Other Studies

26 other study(ies) available for uric acid and ALS - Amyotrophic Lateral Sclerosis

Article	Year
Serum uric acid level predicts the progression of amyotrophic lateral sclerosis following treatment with edaravone. Redox report : communications in free radical research, 2022, Volume: 27, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Edaravone; Humans; Oxidative Stress; Uric Acid	2022
Associations between the ALSFRS-R score and urate levels during 12 months of edaravone treatment for amyotrophic lateral sclerosis: Post hoc analysis of ALSFRS-R scores in clinical studies MCI186-16, MCI186-17, and MCI186-19. Muscle & nerve, 2022, Volume: 66, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Disease Progression; Edaravone; Free Radical Scavengers; Humans; Uric Acid	2022
Unbiased metabolome screen links serum urate to risk of Alzheimer's disease. Neurobiology of aging, 2022, Volume: 120 Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Genome-Wide Association Study; Humans; Mendelian Randomization Analysis; Metabolome; Neurodegenerative Diseases; Parkinson Disease; Polymorphism, Single Nucleotide; Uric Acid	2022
Gender-specific association of uric acid and survival in sporadic amyotrophic lateral sclerosis patients. Brain research, 2023, 09-15, Volume: 1815 Topics: Amyotrophic Lateral Sclerosis; Creatinine; Female; Humans; Male; Uric Acid	2023
[The influence of uric acid on the course of amyotrophic lateral sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2023, Volume: 123, Issue:5 Topics: Amyotrophic Lateral Sclerosis; Antioxidants; Gout; Humans; Male; Neuroprotection; Uric Acid	2023
[Progress in the application of uric acid-lowering treatments in amyotrophic lateral sclerosis]. Zhonghua nei ke za zhi, 2023, Jul-01, Volume: 62, Issue:7 Topics: Amyotrophic Lateral Sclerosis; Humans; Uric Acid	2023
Plasma creatinine and oxidative stress biomarkers in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2020, Volume: 21, Issue:3-4 Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Biomarkers; Cohort Studies; Creatinine; Cross-Sectional Studies; Female; Humans; Longitudinal Studies; Male; Middle Aged; Oxidative Stress; Prospective Studies; Survival Rate; Uric Acid	2020
Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded Pooled Resource Open-Access ALS clinical trials database. Muscle & nerve, 2018, Volume: 57, Issue:3 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Databases, Factual; Disease Progression; Female; Humans; Male; Middle Aged; Prognosis; Survival Rate; Uric Acid	2018
Pre-diagnostic plasma urate and the risk of amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2018, Volume: 19, Issue:3-4 Topics: Aged; Amyotrophic Lateral Sclerosis; Case-Control Studies; Cohort Studies; Colorimetry; Female; Humans; Logistic Models; Male; Middle Aged; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; United States; Uric Acid	2018
Urate mitigates oxidative stress and motor neuron toxicity of astrocytes derived from ALS-linked SOD1 Molecular and cellular neurosciences, 2018, Volume: 92 Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Astrocytes; Cell Line; Cells, Cultured; Culture Media, Conditioned; Mice; Motor Neurons; Mutation; Oxidative Stress; Superoxide Dismutase-1; Uric Acid	2018
Neuroprotection by urate on the mutant hSOD1-related cellular and Drosophila models of amyotrophic lateral sclerosis: Implication for GSH synthesis via activating Akt/GSK3β/Nrf2/GCLC pathways. Brain research bulletin, 2019, Volume: 146 Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Cell Line, Tumor; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Glutamate-Cysteine Ligase; Glutathione; Glycogen Synthase Kinase 3 beta; Male; Mice; Motor Neurons; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Uric Acid	2019
Clinical disease stage related changes of serological factors in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2019, Volume: 20, Issue:1-2 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Blood Proteins; Case-Control Studies; Cholesterol; Creatinine; Disease Progression; Female; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Longitudinal Studies; Male; Middle Aged; Serum Albumin; Uric Acid	2019
Serum uric acid level is associated with the prevalence but not with survival of amyotrophic lateral sclerosis in a Chinese population. Metabolic brain disease, 2014, Volume: 29, Issue:3 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; China; Disease Progression; Female; Humans; Male; Middle Aged; Prevalence; Survival Rate; Uric Acid	2014
[Association of serum uric acid level with amyotrophic lateral sclerosis]. Zhonghua yi xue za zhi, 2016, Jan-19, Volume: 96, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Blood Urea Nitrogen; Disease Progression; Humans; Logistic Models; Uric Acid	2016
Low uric acid levels in serum of patients with ALS: further evidence for oxidative stress? Journal of the neurological sciences, 2009, Oct-15, Volume: 285, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Body Mass Index; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxidative Stress; Severity of Illness Index; Sex Characteristics; Time Factors; Uric Acid	2009
Do serum uric acid levels reflect oxidative stress in the progression of ALS? Journal of the neurological sciences, 2009, Dec-15, Volume: 287, Issue:1-2 Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Body Mass Index; Central Nervous System; Creatinine; Disease Progression; Down-Regulation; Emaciation; Female; Humans; Male; Middle Aged; Muscular Atrophy; Oxidative Stress; Predictive Value of Tests; Respiratory Paralysis; Uric Acid; Vital Capacity	2009
Different roles of radical scavengers--ascorbate and urate in the cerebrospinal fluid of amyotrophic lateral sclerosis patients. Redox report : communications in free radical research, 2010, Volume: 15, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Ascorbic Acid; Cerebrospinal Fluid; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Uric Acid	2010
An exploratory study of serum urate levels in patients with amyotrophic lateral sclerosis. Journal of neurology, 2011, Volume: 258, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Uric Acid	2011
Uric acid levels predict survival in men with amyotrophic lateral sclerosis. Journal of neurology, 2012, Volume: 259, Issue:9 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Proportional Hazards Models; Sex Characteristics; Survival Analysis; Uric Acid	2012
Relationships between disease progression and serum levels of lipid, urate, creatinine and ferritin in Japanese patients with amyotrophic lateral sclerosis: a cross-sectional study. Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:12 Topics: Aged; Amyotrophic Lateral Sclerosis; Asian People; Case-Control Studies; Creatinine; Cross-Sectional Studies; Disease Progression; Female; Ferritins; Humans; Lipids; Logistic Models; Male; Middle Aged; Uric Acid; Vital Capacity	2012
An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients. Journal of the neurological sciences, 2005, Jan-15, Volume: 228, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Ascorbic Acid; Bilirubin; Case-Control Studies; Chromatography, High Pressure Liquid; Coenzymes; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxidation-Reduction; Statistics, Nonparametric; Time Factors; Ubiquinone; Uric Acid	2005
Superoxide-dependent peroxidase activity of H48Q: a superoxide dismutase variant associated with familial amyotrophic lateral sclerosis. Archives of biochemistry and biophysics, 1997, Oct-15, Volume: 346, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Binding Sites; Cloning, Molecular; Copper; Cytochrome c Group; Escherichia coli; Hydrogen Peroxide; Mutation; Oxidation-Reduction; Recombinant Proteins; Superoxide Dismutase; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase	1997
The familial amyotrophic lateral sclerosis-associated amino acid substitutions E100G, G93A, and G93R do not influence the rate of inactivation of copper- and zinc-containing superoxide dismutase by H2O2. Archives of biochemistry and biophysics, 1998, Apr-15, Volume: 352, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Enzyme Stability; Humans; Hydrogen Peroxide; Kinetics; Metalloproteins; Mutation; Peroxidases; Superoxide Dismutase; Uric Acid	1998
Motor neuron disease: retrospective study of associated abnormalities. Diseases of the nervous system, 1976, Volume: 37, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Amyotrophic Lateral Sclerosis; Blood Pressure; Bone and Bones; Bone Diseases; Calcinosis; Calcium; Female; Humans; Male; Middle Aged; Motor Neurons; Muscular Atrophy; Neuromuscular Diseases; Phosphates; Radiography; Retrospective Studies; Uric Acid	1976
Medical Grand Rounds from the University of Alabama Medical Center. Lead poisoning. Southern medical journal, 1972, Volume: 65, Issue:3 Topics: Adult; Aged; Alcoholism; Amyotrophic Lateral Sclerosis; Anemia, Macrocytic; Brain Diseases; Diagnosis, Differential; Environmental Exposure; Gout; Heme; Humans; Hydro-Lyases; Hypertension, Renal; Kidney Diseases; Lead; Lead Poisoning; Male; Middle Aged; Nephritis, Interstitial; Nervous System Diseases; Peripheral Nervous System Diseases; Psychoses, Alcoholic; Uric Acid	1972
[Change in the uric acid content in the blood serum and urine in amyotrophic lateral sclerosis]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1974, Volume: 74, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Diet; Humans; Purines; Spectrophotometry; Uric Acid	1974