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urethane and Precancerous Conditions

urethane has been researched along with Precancerous Conditions in 26 studies

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
"In the A/J strain of mice, urethane (ethyl carbamate) induces lung hyperplasia, adenoma, and adenocarcinoma in a time-dependent manner."3.69Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. ( Chen, A; Horio, Y; Malkinson, AM; Rice, P; Roth, JA; Schrump, DS, 1996)
"Lung cancer is the leading cause of cancer-related death worldwide."1.38Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. ( Hayakawa, T; Imai, T; Imaida, K; Komiya, M; Mutoh, M; Takahashi, M; Tsuta, K; Ueno, T; Wakabayashi, K; Yanaka, A; Yoshimoto, M, 2012)
"The development of hepatic enzyme-altered foci (ATPase, GGTase) was investigated after dosing vinyl acetate (200 and 400 mg/kg per day, orally) to newborn rats for 3 weeks, with or without subsequent promotion by phenobarbital."1.27Vinyl acetate, a structural analog of vinyl carbamate, fails to induce enzyme-altered foci in rat liver. ( Bolt, HM; Laib, RJ, 1986)
"All types of ductal hyperplasias are characterized by intraductal epithelial hyperplasia and have been shown to give rise to mammal adenocarcinomas in situ or by transplantation into the mammary gland-free fat pads of syngeneic mice."1.26Preneoplastic lesions in murine mammary cancer. ( Medina, D, 1976)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199020 (76.92)18.7374
1990's5 (19.23)18.2507
2000's0 (0.00)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ueno, T1
Imaida, K1
Yoshimoto, M1
Hayakawa, T1
Takahashi, M1
Imai, T1
Yanaka, A1
Tsuta, K1
Komiya, M1
Wakabayashi, K1
Mutoh, M1
Scherer, E2
Steward, AP1
Emmelot, P2
Horio, Y1
Chen, A1
Rice, P1
Roth, JA1
Malkinson, AM1
Schrump, DS1
Yano, T1
Yano, Y1
Uchida, M1
Murakami, A1
Hagiwara, K1
Otani, S1
Ichikawa, T1
Cazorla, M1
Hernández, L1
Fernández, PL1
Fabra, A1
Peinado, MA1
Dasenbrock, C1
Tillmann, T1
Kamino, K1
Campo, E1
Kohler, M1
Morawieltz, G1
Cardesa, A1
Tomatis, L1
Mohr, U1
Medina, D6
Gullino, PM1
Warner, MR1
Nelson, MA1
Futscher, BW1
Kinsella, T1
Wymer, J1
Bowden, GT1
Enzmann, H1
Kaliner, G1
Watta-Gebert, B1
Löser, E1
Jiang, TL1
Yan, SC1
Zhao, LF1
Laib, RJ1
Bolt, HM1
Agassy-Cahalon, L1
Yaakubowicz, M1
Witz, IP1
Smorodinsky, NI1
Winterwerp, H1
Shabad, LM2
Kolesnichenko, TS1
Smetanin, EY1
Kondrat'eva, AF1
Frankfurt, OS1
Raitcheva, E1
Ryser, HJ1
Hatziolos, BC1
Thomas, C1
So, BT1
Kolechichenko, TS1
Kvitnitskaia, VA1
DeOme, KB1

Reviews

2 reviews available for urethane and Precancerous Conditions

ArticleYear
[The combined action of ionizing radiation and carcinogens].
    Voprosy onkologii, 1969, Volume: 15, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma,

1969
Chemical carcinogenesis.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: Acetates; Aflatoxins; Alkylating Agents; Alkylation; Amides; Animals; Azo Compounds; Benz(a)Anthrace

1971

Other Studies

24 other studies available for urethane and Precancerous Conditions

ArticleYear
Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice.
    Anticancer research, 2012, Volume: 32, Issue:11

    Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinogens; Humans; Hyperplasia; Immunohis

2012
Formation of precancerous islands in rat liver and modification of DNA by ethyl carbamate: implications for its metabolism.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Biotransformation; Carcinogens; DNA; Female; Liver Neoplasms; Neoplasms, Experimental; Prec

1980
Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Disease Progression; Exons; Genes, p53

1996
The modulation effect of vitamin E on prostaglandin E2 level and ornithine decarboxylase activity at the promotion phase of lung tumorigenesis in mice.
    Biochemical pharmacology, 1997, Jun-01, Volume: 53, Issue:11

    Topics: Animals; Dinoprostone; Down-Regulation; Enzyme Induction; Lung Neoplasms; Male; Mice; Ornithine Deca

1997
Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice.
    Molecular carcinogenesis, 1998, Volume: 21, Issue:4

    Topics: Adenoma; Animals; Carcinoma; Cell Transformation, Neoplastic; Codon; Disease Progression; DNA, Neopl

1998
Serial transplantation of chemical carcinogen-induced mouse mammary ductal dysplasias.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experiment

1979
Preneoplastic lesions in murine mammary cancer.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Hyperplasia; Mammary Neop

1976
Considerations on the preneoplastic lesions of the mammary gland.
    The American journal of pathology, 1977, Volume: 89, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Bromocriptine; Cell Transformat

1977
Mammary tumorigenesis in chemical carcinogen-treated mice. IV. Induction of mammary ductal hyperplasias.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Female; Hyperplasia; Mammary

1976
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jul-15, Volume: 89, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Ne

1992
Foci of altered hepatocytes induced in embryonal turkey liver.
    Carcinogenesis, 1992, Volume: 13, Issue:6

    Topics: Animals; Glucosephosphate Dehydrogenase; Glycogen; Liver; Liver Neoplasms; Nitrosamines; Precancerou

1992
Preventing effect of "liuwei dihuang decoction" on esophageal carcinoma.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2

    Topics: Animals; Cell Nucleus; Cyclic AMP; Cyclophosphamide; Drugs, Chinese Herbal; Epithelium; Esophageal N

1989
Vinyl acetate, a structural analog of vinyl carbamate, fails to induce enzyme-altered foci in rat liver.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: Adenosine Triphosphatases; Animals; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental;

1986
The immune system during the precancer period: naturally-occurring tumor reactive monoclonal antibodies and urethane carcinogenesis.
    Immunology letters, 1988, Volume: 18, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Immunity, Innate; Leukemia L5178; Lung Neopla

1988
Modification of DNA and metabolism of ethyl carbamate in vivo: formation of 7-(2-oxoethyl)guanine and its sensitive determination by reductive tritiation using 3H-sodium borohydride.
    IARC scientific publications, 1986, Issue:70

    Topics: Animals; Biotransformation; Borohydrides; Carcinogens; Cross-Linking Reagents; DNA Damage; Guanine;

1986
Transplacental blastomogenesis in organ cultures of embryonic lung tissue.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:5

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Carcinogens; Female; Hyperplasia; Injections,

1971
Fast onset of DNA synthesis stimulated by tumor promotor in mouse epidermis at the initation stage of carcinogenesis.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:6

    Topics: Animals; Autoradiography; Benz(a)Anthracenes; Benzopyrenes; Croton Oil; DNA; DNA Replication; Female

1973
Mammary tumorigenesis in chemical carcinogen-treated mice. I. Incidence in BALB-c and C57BL mice.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:1

    Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Carcinogens; Hyperplasia; Mammary Neoplasms, Experiment

1974
Urethan injections in newborn calves inoculated with murine lymphosarcoma material.
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1972, Volume: 19, Issue:5

    Topics: Animals; Cattle; Cattle Diseases; Injections, Intraperitoneal; Injections, Intravenous; Leukemia; Ly

1972
Dose-response studies in experimentally induced lung tumours.
    Environmental research, 1971, Volume: 4, Issue:4

    Topics: Adenocarcinoma; Adenoma; Air Pollution; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Carc

1971
[Morphology of N-nitroso-compound induced tumors in the upper digestive tract of rats].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:7

    Topics: Amino Alcohols; Animals; Carcinogens; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esters; Ethyla

1969
[The short-term transplacental effect of urethane on organ cultures of embryonic mouse lung tissue].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:2

    Topics: Animals; Culture Techniques; Embryo, Mammalian; Female; Hyperplasia; Lung Diseases; Maternal-Fetal E

1970
Carcinogen-induced mammary tumors from preneoplastic nodule outgrowths in BALB-c mice.
    Cancer research, 1970, Volume: 30, Issue:4

    Topics: Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Mammary Neoplasms, Experimenta

1970
Effect of hormone stimulation, dose, and time of administration of carcinogen on carcinogen-induced mammary tumors from preneoplastic nodule outgrowths.
    Journal of the National Cancer Institute, 1971, Volume: 46, Issue:4

    Topics: Animals; Benz(a)Anthracenes; Carcinogens; Mammary Glands, Animal; Mammary Neoplasms, Experimental; M

1971