Page last updated: 2024-11-05

urethane and Papilloma

urethane has been researched along with Papilloma in 47 studies

Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"The number of papillomas that develop in mice initiated with a single exposure to urethane and promoted by repeated applications of 12-O-tetradecanoylphorbol-13-acetate (TPA) is increased greater than 4-fold by pretreating the skin once with TPA 24 hr before administration of urethane."7.68Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion. ( Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH, 1991)
" Promotion by mezerein as well as carcinogenesis by repeated treatment with DMBA or MNNG produced papillomas with a high frequency of conversion to squamous cell carcinomas (SCCs)."3.69New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin. ( Hennings, H; Lowry, DT; Mock, B; Potter, M; Yuspa, SH, 1997)
"The number of papillomas that develop in mice initiated with a single exposure to urethane and promoted by repeated applications of 12-O-tetradecanoylphorbol-13-acetate (TPA) is increased greater than 4-fold by pretreating the skin once with TPA 24 hr before administration of urethane."3.68Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion. ( Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH, 1991)
"Mouse skin tumors, benign papillomas, and squamous cell carcinomas (SCCs) were initiated by a single topical application of urethane followed by repeated promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA)."3.67Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane. ( Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA, 1989)
"The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation."1.28Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991)
"The study on morphogenesis of squamous cell carcinomas arising from the upper digestive tract indicates that the majority of tumors of the esophagus and forestomach may pass through acanthosis or hyperkeratosis, leukokeratosis, and papilloma, and finally develop into invasive squamous cell carcinoma, but many carcinomas of the oral cavity and pharnyx, especially the tongue, may develop without passing through a papillomatous stage."1.26Tumors of the upper digestive tract of ACI/N rats given N-propyl-N-nitrosourethan in the drinking water. ( Kamiya, S; Maekawa, A; Odashima, S, 1976)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199038 (80.85)18.7374
1990's8 (17.02)18.2507
2000's1 (2.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BERENBLUM, I3
HARAN-GHERA, N1
POUND, AW3
CHIECO-BIANCHI, L1
DEBENEDICTIS, G1
TRIDENTE, G1
FIORE-DONATI, L1
Shinozuka, H1
Ritchie, AC1
Iversen, OH1
Astrup, EG1
Armuth, V2
Onodera, H1
Furuta, K1
Matsuoka, C1
Kamiya, S3
Maekawa, A3
Hirono, I1
Hosaka, S1
Kuhara, K1
Park, KK2
Surh, YJ2
Miller, JA2
Shlyankevich, M1
Hennings, H8
Lowry, DT1
Yuspa, SH4
Mock, B1
Potter, M1
Saran, A1
Zaffaroni, D1
Pazzaglia, S1
Peissel, B1
Galbiati, F1
Spinola, M1
Manenti, G1
Zanesi, N1
Rebessi, S1
Mancuso, MT1
Covelli, V1
Dragani, TA1
Dahl, GA1
Miller, EC1
Brem, SS1
Gullino, PM1
Medina, D1
Hirose, M1
Odashima, S2
Fujii, M1
Nelson, MA1
Futscher, BW1
Kinsella, T1
Wymer, J1
Bowden, GT5
Robinson, VA1
Welty, DJ1
Greenhalgh, DG1
Shores, R1
Balaschak, M1
Shores, RA1
Poirier, MC1
Reed, E1
Tarone, RE2
Bonham, K1
Embry, T1
Gibson, D1
Jaffe, DR1
Roberts, RA1
Cress, AE1
Chu, KC1
Brown, CC1
Tan, WY1
Carlson, GP1
Fossa, AA1
Morse, MA1
Weaver, PM1
Barnhart, KM1
Shimkin, MB1
Mirvish, SS1
Pogosiants, EE1
Sokova, OI1
Prigozhina, EL1
Kondrat'eva, AF1
Mohr, U1
Reznik, G1
Reznik-Schüller, H1
Slaga, TJ1
Shapas, BG1
Boutwell, RK3
Michael, D1
Patterson, E1
Turusov, VS1
Cioli, V1
Scorza Barcellona, P1
Silvestrini, B1
Hartwich, G1
Butzler, W1
Roe, FJ1
Carter, RL1
Mitchley, BC1
Peto, R1
Hecker, E1
Thomas, C1
So, BT1
Toth, B1
Yasuhira, K3

Reviews

4 reviews available for urethane and Papilloma

ArticleYear
The paradigm of two-stage carcinogenesis: a critical attitude.
    Cancer investigation, 1984, Volume: 2, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholan

1984
The carcinogenic action and metabolism of urethan and N-hydroxyurethan.
    Advances in cancer research, 1968, Volume: 11

    Topics: Adenoma; Animals; Animals, Newborn; Body Fluids; Breast Neoplasms; Carbamates; Carcinogens; Carcinom

1968
[The combined action of ionizing radiation and carcinogens].
    Voprosy onkologii, 1969, Volume: 15, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma,

1969
[On the problem of cocarcinogenesis].
    Voprosy onkologii, 1969, Volume: 15, Issue:6

    Topics: Animals; Carcinogens; Croton Oil; Mice; Neoplasms; Neoplasms, Experimental; Papilloma; Sarcoma, Expe

1969

Other Studies

43 other studies available for urethane and Papilloma

ArticleYear
Papilloma formation in the forestomach of the mouse following oral administration of urethan (ethyl carbamate).
    Cancer research, 1957, Volume: 17, Issue:4

    Topics: Administration, Oral; Animals; Mice; Neoplasms, Experimental; Papilloma; Stomach Neoplasms; Urethane

1957
The localisation of the influence of croton oil stimulation on tumour initiation by urethane in mice.
    The Australian journal of experimental biology and medical science, 1963, Volume: 41

    Topics: Animals; Cell Transformation, Neoplastic; Croton Oil; Mice; Neoplasms; Neoplasms, Experimental; Papi

1963
INFLUENCE OF AGE ON SUSCEPTIBILITY TO LIVER CARCINOGENESIS AND SKIN INITIATING ACTION BY URETHANE IN SWISS MICE.
    British journal of cancer, 1963, Volume: 17

    Topics: Aging; Animals; Animals, Newborn; Carcinogenesis; Carcinoma, Hepatocellular; Croton Oil; Female; Hum

1963
The initiation of tumour formation by urethane in the mouse.
    British journal of cancer, 1962, Volume: 16

    Topics: Animals; Mice; Neoplasms; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Urethane

1962
Pretreatment with croton oil, DNA synthesis, and carcinogenesis by carcinogen followed by croton oil.
    International journal of cancer, 1967, Mar-15, Volume: 2, Issue:2

    Topics: Animals; Benz(a)Anthracenes; Carcinogens; Croton Oil; DNA; Mice; Neoplasms, Experimental; Papilloma;

1967
Further exploration of stages in carcinogenesis.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Caffeine; Cocarcinogenesis; Female; Isoxazoles; Mice; Mice, Inbred ICR; Neoplasms, Experime

1982
Carcinogenicities of 1-ethyl- and 1-amyl-1-nitrosourethans in female donryu rats: dose-effect relations.
    Gan, 1982, Volume: 73, Issue:1

    Topics: Animals; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Duodenal Neoplasms; Esophageal Ne

1982
Enhancement by bracken of induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan.
    British journal of cancer, 1982, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Gastrointestinal Ne

1982
The effect of caffeine on two-stage skin carcinogenesis and on complete systemic carcinogenesis.
    Carcinogenesis, 1981, Volume: 2, Issue:10

    Topics: Adenoma; Animals; Caffeine; Drug Interactions; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neopl

1981
Chemoprotective properties of chlorophyllin against vinyl carbamate, p-nitrophenyl vinyl ether and their electrophilic epoxides.
    Cancer letters, 1995, Jul-20, Volume: 94, Issue:1

    Topics: Animals; Antimutagenic Agents; Chlorophyllides; DNA Adducts; Dose-Response Relationship, Drug; Epoxy

1995
Inhibitory effects of chlorophyllin on chemically induced mutagenesis and carcinogenesis.
    Annals of the New York Academy of Sciences, 1995, Sep-30, Volume: 768

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Antimutagenic

1995
New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis;

1997
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
    International journal of cancer, 2002, Feb-10, Volume: 97, Issue:5

    Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Pred

2002
Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 1

    Topics: Adenoma; Animals; Biotransformation; Carcinogens; Female; In Vitro Techniques; Lung Neoplasms; Mice;

1978
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia.
    Science (New York, N.Y.), 1977, Mar-04, Volume: 195, Issue:4281

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Iri

1977
Carcinogenic effect of N-ethyl- and N-amyl-N-nitrosourethans on female Donryu rats.
    Gan, 1979, Volume: 70, Issue:5

    Topics: Administration, Oral; Administration, Topical; Animals; Carcinoma; Duodenal Neoplasms; Esophageal Ne

1979
Carcinogenic effect of N-butyl-N-nitrosourethan on CDF1 mice.
    Gan, 1976, Volume: 67, Issue:2

    Topics: Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Transformatio

1976
Tumors of the upper digestive tract of ACI/N rats given N-propyl-N-nitrosourethan in the drinking water.
    Gan, 1976, Volume: 67, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Female; Intestinal Neoplasms; Leukoplakia; Male; Mouth Neoplasms;

1976
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jul-15, Volume: 89, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Ne

1992
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
    Basic life sciences, 1991, Volume: 57

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce

1991
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
    Cancer communications, 1991, Volume: 3, Issue:9

    Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation,

1991
Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Mi

1990
Enhanced malignant conversion of benign mouse skin tumors by cisplatin.
    Journal of the National Cancer Institute, 1990, May-16, Volume: 82, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cisplatin; DNA; Female; Mice; Papilloma; Skin

1990
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
    Molecular carcinogenesis, 1989, Volume: 2, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Pro

1989
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Mode

1987
Binding and distribution studies in the SENCAR mouse of compounds demonstrating a route-dependent tumorigenic effect.
    Environmental health perspectives, 1986, Volume: 68

    Topics: Acrylamide; Acrylamides; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene; Car

1986
Cisplatin as an initiating agent in two-stage mouse skin carcinogenesis.
    Cancer letters, 1985, Volume: 29, Issue:1

    Topics: Animals; Carcinogens; Cisplatin; Cocarcinogenesis; Female; Injections, Intraperitoneal; Mice; Papill

1985
Biological tests of carcinogenic activity.
    Archives of environmental health, 1968, Volume: 16, Issue:4

    Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla

1968
[A new animal for experimental oncologic research--the Dzhungarian hamster].
    Voprosy onkologii, 1970, Volume: 16, Issue:3

    Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel

1970
Urethan as a carcinogen for the European hamster.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:5

    Topics: Adrenal Gland Neoplasms; Animals; Carcinogens; Cricetinae; Female; Fibrosarcoma; Injections, Intrape

1974
Macromolecular synthesis following a single application of alkylating agents used as initiators of mouse skin tumorigenesis.
    Cancer research, 1973, Volume: 33, Issue:4

    Topics: Alkylating Agents; Animals; Croton Oil; Cytidine; DNA; Female; Hyperplasia; Leucine; Mice; Neoplasms

1973
Enhancement of skin tumorigenesis by a single application of croton oil before or soon after initiation by urethan.
    Cancer research, 1973, Volume: 33, Issue:12

    Topics: Animals; Cell Division; Croton Oil; DNA; DNA Replication; Female; Hydroxyurea; Mice; Neoplasms, Expe

1973
Study of the potential carcinogenicity of topical drug. Suggestions for a new experimental approach.
    Experimental and molecular pathology, 1971, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Administration, Topical; Animals; Anti-Inflammatory Agents; Bronchial Neoplasms; Car

1971
[Secondary tumors in hemoblastoses during cytostatic treatment].
    Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo

1971
On the persistence of tumour initiation and the acceleration of tumour progression in mouse skin tumorigenesis.
    International journal of cancer, 1972, Mar-15, Volume: 9, Issue:2

    Topics: Acetone; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Croton Oil; Female; Mice; Neo

1972
Tumour formation in mice by urethane administered with related carbamates.
    British journal of cancer, 1972, Volume: 26, Issue:3

    Topics: Animals; Carbamates; Carcinoma; Carcinoma, Squamous Cell; Croton Oil; Drug Interactions; Esters; Inj

1972
[Morphology of N-nitroso-compound induced tumors in the upper digestive tract of rats].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:7

    Topics: Amino Alcohols; Animals; Carcinogens; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esters; Ethyla

1969
Tumor induction with single urethan injection in newborn and adult syrian golden hamsters. A study on age influence. I.
    International journal of cancer, 1970, Jul-15, Volume: 6, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Cricetinae; Female; Male; Neoplasms, Experimental; Papilloma

1970
Skin papilloma production by Anthralin painting after urethan initiation in mice.
    Gan, 1968, Volume: 59, Issue:3

    Topics: Animals; Anthracenes; Croton Oil; Injections, Intraperitoneal; Mice; Neoplasms, Experimental; Papill

1968
Induction of malignant lymphoma and other tumors during experiments with anthralin painting of mice.
    Gan, 1968, Volume: 59, Issue:3

    Topics: Acetone; Adenoma; Animals; Anthracenes; Carcinoma; Injections, Intraperitoneal; Lung Neoplasms; Lymp

1968
The inhibition of DNA synthesis by initiators of mouse skin tumorigenesis.
    Cancer research, 1969, Volume: 29, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Carcinogens; DNA; Lactones; Neoplasms, Experimental; Papilloma; Quinoli

1969
Suspicious influence of thymectomy on skin papilloma induction.
    Gan, 1969, Volume: 60, Issue:1

    Topics: Animals; Croton Oil; Graft vs Host Disease; Methylcholanthrene; Mice; Papilloma; Skin Neoplasms; Thy

1969
The effect of croton oil pretreatment on skin tumor initiation in mice.
    Cancer research, 1969, Volume: 29, Issue:10

    Topics: Alkylating Agents; Animals; Benz(a)Anthracenes; Carcinoma; Chromatography; Croton Oil; DNA; Female;

1969