urethane has been researched along with Papilloma in 47 studies
Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The number of papillomas that develop in mice initiated with a single exposure to urethane and promoted by repeated applications of 12-O-tetradecanoylphorbol-13-acetate (TPA) is increased greater than 4-fold by pretreating the skin once with TPA 24 hr before administration of urethane." | 7.68 | Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion. ( Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH, 1991) |
| " Promotion by mezerein as well as carcinogenesis by repeated treatment with DMBA or MNNG produced papillomas with a high frequency of conversion to squamous cell carcinomas (SCCs)." | 3.69 | New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin. ( Hennings, H; Lowry, DT; Mock, B; Potter, M; Yuspa, SH, 1997) |
| "The number of papillomas that develop in mice initiated with a single exposure to urethane and promoted by repeated applications of 12-O-tetradecanoylphorbol-13-acetate (TPA) is increased greater than 4-fold by pretreating the skin once with TPA 24 hr before administration of urethane." | 3.68 | Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion. ( Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH, 1991) |
| "Mouse skin tumors, benign papillomas, and squamous cell carcinomas (SCCs) were initiated by a single topical application of urethane followed by repeated promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA)." | 3.67 | Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane. ( Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA, 1989) |
| "The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation." | 1.28 | Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991) |
| "The study on morphogenesis of squamous cell carcinomas arising from the upper digestive tract indicates that the majority of tumors of the esophagus and forestomach may pass through acanthosis or hyperkeratosis, leukokeratosis, and papilloma, and finally develop into invasive squamous cell carcinoma, but many carcinomas of the oral cavity and pharnyx, especially the tongue, may develop without passing through a papillomatous stage." | 1.26 | Tumors of the upper digestive tract of ACI/N rats given N-propyl-N-nitrosourethan in the drinking water. ( Kamiya, S; Maekawa, A; Odashima, S, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (80.85) | 18.7374 |
| 1990's | 8 (17.02) | 18.2507 |
| 2000's | 1 (2.13) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERENBLUM, I | 3 |
| HARAN-GHERA, N | 1 |
| POUND, AW | 3 |
| CHIECO-BIANCHI, L | 1 |
| DEBENEDICTIS, G | 1 |
| TRIDENTE, G | 1 |
| FIORE-DONATI, L | 1 |
| Shinozuka, H | 1 |
| Ritchie, AC | 1 |
| Iversen, OH | 1 |
| Astrup, EG | 1 |
| Armuth, V | 2 |
| Onodera, H | 1 |
| Furuta, K | 1 |
| Matsuoka, C | 1 |
| Kamiya, S | 3 |
| Maekawa, A | 3 |
| Hirono, I | 1 |
| Hosaka, S | 1 |
| Kuhara, K | 1 |
| Park, KK | 2 |
| Surh, YJ | 2 |
| Miller, JA | 2 |
| Shlyankevich, M | 1 |
| Hennings, H | 8 |
| Lowry, DT | 1 |
| Yuspa, SH | 4 |
| Mock, B | 1 |
| Potter, M | 1 |
| Saran, A | 1 |
| Zaffaroni, D | 1 |
| Pazzaglia, S | 1 |
| Peissel, B | 1 |
| Galbiati, F | 1 |
| Spinola, M | 1 |
| Manenti, G | 1 |
| Zanesi, N | 1 |
| Rebessi, S | 1 |
| Mancuso, MT | 1 |
| Covelli, V | 1 |
| Dragani, TA | 1 |
| Dahl, GA | 1 |
| Miller, EC | 1 |
| Brem, SS | 1 |
| Gullino, PM | 1 |
| Medina, D | 1 |
| Hirose, M | 1 |
| Odashima, S | 2 |
| Fujii, M | 1 |
| Nelson, MA | 1 |
| Futscher, BW | 1 |
| Kinsella, T | 1 |
| Wymer, J | 1 |
| Bowden, GT | 5 |
| Robinson, VA | 1 |
| Welty, DJ | 1 |
| Greenhalgh, DG | 1 |
| Shores, R | 1 |
| Balaschak, M | 1 |
| Shores, RA | 1 |
| Poirier, MC | 1 |
| Reed, E | 1 |
| Tarone, RE | 2 |
| Bonham, K | 1 |
| Embry, T | 1 |
| Gibson, D | 1 |
| Jaffe, DR | 1 |
| Roberts, RA | 1 |
| Cress, AE | 1 |
| Chu, KC | 1 |
| Brown, CC | 1 |
| Tan, WY | 1 |
| Carlson, GP | 1 |
| Fossa, AA | 1 |
| Morse, MA | 1 |
| Weaver, PM | 1 |
| Barnhart, KM | 1 |
| Shimkin, MB | 1 |
| Mirvish, SS | 1 |
| Pogosiants, EE | 1 |
| Sokova, OI | 1 |
| Prigozhina, EL | 1 |
| Kondrat'eva, AF | 1 |
| Mohr, U | 1 |
| Reznik, G | 1 |
| Reznik-Schüller, H | 1 |
| Slaga, TJ | 1 |
| Shapas, BG | 1 |
| Boutwell, RK | 3 |
| Michael, D | 1 |
| Patterson, E | 1 |
| Turusov, VS | 1 |
| Cioli, V | 1 |
| Scorza Barcellona, P | 1 |
| Silvestrini, B | 1 |
| Hartwich, G | 1 |
| Butzler, W | 1 |
| Roe, FJ | 1 |
| Carter, RL | 1 |
| Mitchley, BC | 1 |
| Peto, R | 1 |
| Hecker, E | 1 |
| Thomas, C | 1 |
| So, BT | 1 |
| Toth, B | 1 |
| Yasuhira, K | 3 |
4 reviews available for urethane and Papilloma
| Article | Year |
|---|---|
The paradigm of two-stage carcinogenesis: a critical attitude.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholan | 1984 |
The carcinogenic action and metabolism of urethan and N-hydroxyurethan.
Topics: Adenoma; Animals; Animals, Newborn; Body Fluids; Breast Neoplasms; Carbamates; Carcinogens; Carcinom | 1968 |
[The combined action of ionizing radiation and carcinogens].
Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma, | 1969 |
[On the problem of cocarcinogenesis].
Topics: Animals; Carcinogens; Croton Oil; Mice; Neoplasms; Neoplasms, Experimental; Papilloma; Sarcoma, Expe | 1969 |
43 other studies available for urethane and Papilloma
| Article | Year |
|---|---|
Papilloma formation in the forestomach of the mouse following oral administration of urethan (ethyl carbamate).
Topics: Administration, Oral; Animals; Mice; Neoplasms, Experimental; Papilloma; Stomach Neoplasms; Urethane | 1957 |
The localisation of the influence of croton oil stimulation on tumour initiation by urethane in mice.
Topics: Animals; Cell Transformation, Neoplastic; Croton Oil; Mice; Neoplasms; Neoplasms, Experimental; Papi | 1963 |
INFLUENCE OF AGE ON SUSCEPTIBILITY TO LIVER CARCINOGENESIS AND SKIN INITIATING ACTION BY URETHANE IN SWISS MICE.
Topics: Aging; Animals; Animals, Newborn; Carcinogenesis; Carcinoma, Hepatocellular; Croton Oil; Female; Hum | 1963 |
The initiation of tumour formation by urethane in the mouse.
Topics: Animals; Mice; Neoplasms; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Urethane | 1962 |
Pretreatment with croton oil, DNA synthesis, and carcinogenesis by carcinogen followed by croton oil.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Croton Oil; DNA; Mice; Neoplasms, Experimental; Papilloma; | 1967 |
Further exploration of stages in carcinogenesis.
Topics: Animals; Caffeine; Cocarcinogenesis; Female; Isoxazoles; Mice; Mice, Inbred ICR; Neoplasms, Experime | 1982 |
Carcinogenicities of 1-ethyl- and 1-amyl-1-nitrosourethans in female donryu rats: dose-effect relations.
Topics: Animals; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Duodenal Neoplasms; Esophageal Ne | 1982 |
Enhancement by bracken of induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Gastrointestinal Ne | 1982 |
The effect of caffeine on two-stage skin carcinogenesis and on complete systemic carcinogenesis.
Topics: Adenoma; Animals; Caffeine; Drug Interactions; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neopl | 1981 |
Chemoprotective properties of chlorophyllin against vinyl carbamate, p-nitrophenyl vinyl ether and their electrophilic epoxides.
Topics: Animals; Antimutagenic Agents; Chlorophyllides; DNA Adducts; Dose-Response Relationship, Drug; Epoxy | 1995 |
Inhibitory effects of chlorophyllin on chemically induced mutagenesis and carcinogenesis.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Antimutagenic | 1995 |
New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; | 1997 |
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Pred | 2002 |
Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate.
Topics: Adenoma; Animals; Biotransformation; Carcinogens; Female; In Vitro Techniques; Lung Neoplasms; Mice; | 1978 |
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Iri | 1977 |
Carcinogenic effect of N-ethyl- and N-amyl-N-nitrosourethans on female Donryu rats.
Topics: Administration, Oral; Administration, Topical; Animals; Carcinoma; Duodenal Neoplasms; Esophageal Ne | 1979 |
Carcinogenic effect of N-butyl-N-nitrosourethan on CDF1 mice.
Topics: Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Transformatio | 1976 |
Tumors of the upper digestive tract of ACI/N rats given N-propyl-N-nitrosourethan in the drinking water.
Topics: Animals; Carcinoma, Squamous Cell; Female; Intestinal Neoplasms; Leukoplakia; Male; Mouth Neoplasms; | 1976 |
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Ne | 1992 |
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce | 1991 |
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, | 1991 |
Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Mi | 1990 |
Enhanced malignant conversion of benign mouse skin tumors by cisplatin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cisplatin; DNA; Female; Mice; Papilloma; Skin | 1990 |
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Pro | 1989 |
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Mode | 1987 |
Binding and distribution studies in the SENCAR mouse of compounds demonstrating a route-dependent tumorigenic effect.
Topics: Acrylamide; Acrylamides; Administration, Oral; Administration, Topical; Animals; Benzo(a)pyrene; Car | 1986 |
Cisplatin as an initiating agent in two-stage mouse skin carcinogenesis.
Topics: Animals; Carcinogens; Cisplatin; Cocarcinogenesis; Female; Injections, Intraperitoneal; Mice; Papill | 1985 |
Biological tests of carcinogenic activity.
Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla | 1968 |
[A new animal for experimental oncologic research--the Dzhungarian hamster].
Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel | 1970 |
Urethan as a carcinogen for the European hamster.
Topics: Adrenal Gland Neoplasms; Animals; Carcinogens; Cricetinae; Female; Fibrosarcoma; Injections, Intrape | 1974 |
Macromolecular synthesis following a single application of alkylating agents used as initiators of mouse skin tumorigenesis.
Topics: Alkylating Agents; Animals; Croton Oil; Cytidine; DNA; Female; Hyperplasia; Leucine; Mice; Neoplasms | 1973 |
Enhancement of skin tumorigenesis by a single application of croton oil before or soon after initiation by urethan.
Topics: Animals; Cell Division; Croton Oil; DNA; DNA Replication; Female; Hydroxyurea; Mice; Neoplasms, Expe | 1973 |
Study of the potential carcinogenicity of topical drug. Suggestions for a new experimental approach.
Topics: Adenocarcinoma; Administration, Topical; Animals; Anti-Inflammatory Agents; Bronchial Neoplasms; Car | 1971 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
On the persistence of tumour initiation and the acceleration of tumour progression in mouse skin tumorigenesis.
Topics: Acetone; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Croton Oil; Female; Mice; Neo | 1972 |
Tumour formation in mice by urethane administered with related carbamates.
Topics: Animals; Carbamates; Carcinoma; Carcinoma, Squamous Cell; Croton Oil; Drug Interactions; Esters; Inj | 1972 |
[Morphology of N-nitroso-compound induced tumors in the upper digestive tract of rats].
Topics: Amino Alcohols; Animals; Carcinogens; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esters; Ethyla | 1969 |
Tumor induction with single urethan injection in newborn and adult syrian golden hamsters. A study on age influence. I.
Topics: Age Factors; Animals; Animals, Newborn; Cricetinae; Female; Male; Neoplasms, Experimental; Papilloma | 1970 |
Skin papilloma production by Anthralin painting after urethan initiation in mice.
Topics: Animals; Anthracenes; Croton Oil; Injections, Intraperitoneal; Mice; Neoplasms, Experimental; Papill | 1968 |
Induction of malignant lymphoma and other tumors during experiments with anthralin painting of mice.
Topics: Acetone; Adenoma; Animals; Anthracenes; Carcinoma; Injections, Intraperitoneal; Lung Neoplasms; Lymp | 1968 |
The inhibition of DNA synthesis by initiators of mouse skin tumorigenesis.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; DNA; Lactones; Neoplasms, Experimental; Papilloma; Quinoli | 1969 |
Suspicious influence of thymectomy on skin papilloma induction.
Topics: Animals; Croton Oil; Graft vs Host Disease; Methylcholanthrene; Mice; Papilloma; Skin Neoplasms; Thy | 1969 |
The effect of croton oil pretreatment on skin tumor initiation in mice.
Topics: Alkylating Agents; Animals; Benz(a)Anthracenes; Carcinoma; Chromatography; Croton Oil; DNA; Female; | 1969 |