urethane has been researched along with Lung Neoplasms in 606 studies
Lung Neoplasms: Tumors or cancer of the LUNG.
Excerpt | Relevance | Reference |
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"To analyze whether TGF-β exerts suppressive or oncogenic actions on mammary carcinogenesis, transgenic mice overexpressing a dominant-negative mutant type II TGF-β receptor (TβRII-DNR) driven by the mouse mammary tumor virus (MMTV) promoter were treated with a low dose of urethane, a carcinogen present in fermented food products and alcoholic beverages." | 7.96 | Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor. ( Kondo, Y; Morimoto, J; Shibata, E; Shibata, MA, 2020) |
"This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis." | 7.91 | Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019) |
" The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane." | 7.79 | The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013) |
" In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18." | 7.76 | Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010) |
" Urethane, a specific lung tumor carcinogen, can induce adenomas in mice." | 7.73 | Altered expression of connexins in urethane-induced mouse lung adenomas. ( Avanzo, JL; da Silva, TC; Dagli, ML; Fukumasu, H; Hernandez-Blazquez, FJ; Mesnil, M; Mori, CM; Yamasaki, H, 2006) |
"Susceptibility to urethane-induced lung adenomas in mice has a polygenic mode of inheritance, with no obvious discontinuity in lung tumour counts among 37 AXB recombinant inbred strains." | 7.69 | At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice. ( Festing, MF; Malkinson, AM; Yang, A, 1994) |
" The ultrastructural characteristics, effect of dexamethasone on cellular morphology and proliferation rate, and the cytoskeletal protein pattern of NAL suggests that these cell strains may be related to a urethane-induced mouse lung adenoma cell strain NUL and to a metastasizing mouse lung tumour cell line CMT." | 7.67 | Establishment of epithelial cell strains from normal adult mouse lung resembling a urethane-induced lung adenoma cell strain and a metastasizing mouse lung carcinoma cell line. ( de Montfort, ML; Le Mesurier, SM; Lykke, AW; Smith, GJ, 1984) |
"0 mg of urethane/g body wt the average diameter and prevalence of lung adenomas in adult strain." | 7.66 | Reduced prevalence and growth rate of urethane-induced lung adenomas in ageing adult strain A mice. ( Baxter, CS; Dourson, ML, 1981) |
"The combination of urethane and the non-steroidal oestrogen diethylstilboestrol induced lymphomas in CFLP mice." | 7.66 | Induction of lymphomas by urethane in combination with diethylstilboestrol in CFLP mice. ( Boján, F; Gomba, Sz; Rédai, I, 1979) |
"Dextramycine as well as leftrotating isomer (chloramphenicol--levomycetin) diminished the blastomogenic effect of urethane which is known to induce lung adenomas in mice." | 7.65 | Dextramycine (the dextraisomer of chloramphenicol) as an inhibitor of the induction of lung adenomas in mice. ( Belitsky, GA; Bogush, TA; Konopleva, IA; Shabad, LM, 1977) |
"The effect of adhesive factor (AF), urethane and their combination on the mechanical properties of lung tissue (this effect was assessed by the nuclei isolation during a standard dispersion procedure) and on adenoma induction was studied." | 7.65 | [Effect of the tissue-specific lung adhesive factor on the urethane induction of pulmonary adenomas in mice]. ( Malenkov, AG; Modianova, EA; Shabad, LM, 1977) |
"Metaphase arrest by vincristine in urethane-induced murine pulmonary adenomas became linear after an interval of 60 min." | 7.65 | Cell kinetics of urethane-induced murine pulmonary adenomas: III. Implications of the disparity between the rates of entry into DNA synthesis and into mitosis. ( Dyson, P; Heppleston, AG, 1977) |
" In experiments described in the present paper we have investigated the influence of CP on the incidence of lung adenomas in mice after administration of urethane." | 7.65 | On the influence of chloramphenicol on the induction of lung adenomas by urethane in mice. ( Belitsky, GA; Bogush, TA; Shabad, LM, 1975) |
"Continuous labelling of urethane induced pulmonary adenomata in adult male A2G mice at intervals up to 20 weeks showed that the growth fraction fell progressively from 18% at 7 weeks to 7% at 20 weeks." | 7.65 | Cell kinetics of urethane-induced murine pulmonary adenomata: II, the growth fraction and cell loss factor. ( Dyson, P; Heppleston, AG, 1976) |
" C strain females in the latter half of pregnancy were injected with urethane and the lungs of their young were searched for adenomas." | 7.63 | The neoplastic potentialities of mouse embryo tissues; lung adenomas in baby mice as result of prenatal exposure to urethane. ( ROUS, P; SMITH, WE, 1948) |
"Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 7.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
"Young, rapidly growing mice are greatly more responsive to the adenoma-inducing influence of urethane than are those just arriving at maturity." | 7.63 | Age of the host and other factors affecting the production with urethane of pulmonary adenomas in mice. ( ROGERS, S, 1951) |
"Chemical induced carcinogenesis together with genetically engineered mouse models represent important approaches for the study of the complex mechanisms involving genotype and environmental factors in cancer development, including lung cancer." | 5.62 | Urethane-induced lung carcinogenesis. ( Del Prete, A; Schioppa, T; Sozio, F; Sozzani, S, 2021) |
"Urethane is a recognized genotoxic carcinogen in fermented foods and beverages." | 5.43 | Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016) |
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62." | 5.43 | The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016) |
"Our data validate chemical carcinogenesis as a suitable "in vivo" model for further and more detailed studies on the molecular mechanisms of the death response induced by Col V in lung infiltrating adenocarcinoma opening new strategies for treatment." | 5.43 | Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model. ( Alveno, RA; Capelozzi, VL; Corrêa, PY; de Morais, J; Fabro, AT; Faustino, CB; Parra, ER; Rangel, MP; Teodoro, WR; Vargas, CM; Velosa, AP, 2016) |
"Lung cancer is a common and highly frequent cause of cancer‑associated mortality worldwide." | 5.43 | Inflammation has a role in urethane‑induced lung cancer in C57BL/6J mice. ( Chen, T; Lian, X; Lin, X; Lu, L; Wei, S; Xu, C; Zhou, L, 2016) |
"Curcumin has long been recognized as a chemopreventive agent, but poor bioavailability and weak Nrf2 induction have prohibited clinical application." | 5.42 | A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response. ( Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B, 2015) |
"Urethane treated SWR mice received 6 fortnightly injections of lymphocytes sensitized in vitro against syngeneic fibroblasts." | 5.25 | Increased incidence of urethane induced lung adenomata by autosensitized lymphocytes. ( Carnaud, C; Cohen, IR; Levo, Y; Trainin, N, 1974) |
" We elucidated the relationship between Nrf2 expression levels and whole exon mutation patterns using an ethyl-carbamate (urethane)-induced lung carcinogenesis model employing Nrf2-deficient and Keap1-kd mice, the latter of which express high levels of Nrf2." | 4.12 | Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels. ( Arai, Y; Furukawa, E; Hama, N; Kato, M; Moriguchi, T; Ohe, Y; Satoh, H; Shibata, T; Totoki, Y; Urushidate, T; Yamamoto, M, 2022) |
"To analyze whether TGF-β exerts suppressive or oncogenic actions on mammary carcinogenesis, transgenic mice overexpressing a dominant-negative mutant type II TGF-β receptor (TβRII-DNR) driven by the mouse mammary tumor virus (MMTV) promoter were treated with a low dose of urethane, a carcinogen present in fermented food products and alcoholic beverages." | 3.96 | Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor. ( Kondo, Y; Morimoto, J; Shibata, E; Shibata, MA, 2020) |
" The effects of activating GPER and function of G15 were analyzed in the proliferation of A549 and H1793 cell lines and development of urethane-induced adenocarcinoma." | 3.91 | G-Protein-Coupled Estrogen Receptor Antagonist G15 Decreases Estrogen-Induced Development of Non-Small Cell Lung Cancer. ( Fan, S; Fu, X; Liao, Y; Liu, C; Wang, J; Xiong, J; Zhou, S; Zou, M, 2019) |
" XPC-/- mice treated with the CS-carcinogen urethane developed lung adenocarcinomas representing progressive stages of tumor development, with lung tumor number increased 17-fold compared with XPC+/+ mice." | 3.91 | XPC protects against smoking- and carcinogen-induced lung adenocarcinoma. ( Saliba, J; Sandusky, GE; Sears, CR; Zhou, H, 2019) |
"This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis." | 3.91 | Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019) |
" In conclusion, AKT1E17K induces hyperplasia of mouse lung epithelium in vivo and cooperates with urethane to induce the fully malignant phenotype." | 3.83 | AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer. ( Belmonte, S; Camastra, C; Colelli, F; De Marco, C; Fagman, H; Gagliardi, M; Malanga, D; Mignogna, C; Mirante, T; Oliveira, DM; Paciello, O; Papparella, S; Rizzuto, A; Scarfò, M; Viglietto, G, 2016) |
" Additionally, in vitro administration of E2 and G1 increased the number of tumor nodules, tumor grade, and tumor index in a urethane-induced adenocarcinoma model." | 3.81 | G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1. ( Fan, S; Jiang, Z; Liao, Y; Liu, C; Tang, H; Wang, J; Xiong, J; Zhou, B; Zhou, S; Zou, M, 2015) |
" A mouse model of urethane-induced lung adenocarcinoma was used in the study." | 3.80 | Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression. ( Chen, G; Fu, S; Liao, Y; Liu, Z; Tang, H; Xu, L; Yu, L; Zhang, C; Zhou, S, 2014) |
" The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane." | 3.79 | The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013) |
" In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18." | 3.76 | Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010) |
" The mice were subjected to the development of OVA-induced allergic asthma and urethane-induced lung cancer." | 3.76 | In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse. ( Chen, Y; Ding, Q; Li, Z; Luo, X; Mao, K; Pan, Y; Sun, B; Wang, M; Wang, Z; Zang, YQ, 2010) |
" Lung adenoma was induced in mice by urethane injection followed by different periods of FTY720 administration in order to evaluate lung tumor development." | 3.75 | FTY720 and lung tumor development. ( Bueno, V; Cordeiro, JA; Cury, PM; Oshima, CT; Salinas, NR, 2009) |
" Lung adenocarcinomas were induced in A/J mice by injection of the carcinogen vinyl carbamate." | 3.75 | Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice. ( Liby, K; Ma, T; Risingsong, R; Royce, DB; Sporn, MB; Williams, CR; Yore, MM, 2009) |
" Female A/J mice were treated with the mutagenic carcinogen vinyl carbamate, which induces adenocarcinoma of the lung in all animals within 16 weeks." | 3.74 | The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. ( Dmitrovsky, E; Gribble, GW; Honda, T; Liby, K; Risingsong, R; Royce, DB; Sporn, MB; Sporn, TA; Williams, CR; Yore, MM, 2007) |
" The goal of this work was to monitor quantitatively the development and progression of adenocarcinoma in a time course study of mice treated with the carcinogen urethane using in vivo small-animal magnetic resonance imaging (MRI)." | 3.74 | Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging. ( Garbow, JR; Lubet, RA; Wang, M; Wang, Y; You, M, 2008) |
" We show herein that resistant C57BL/6J (B6) and intermediately resistant BALB/cByJ (BALB) mice form very few urethane-induced early microadenomas (i." | 3.73 | Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis. ( Dwyer-Nield, LD; Kisley, LR; Malkinson, AM; O'Donnell, EP; Zerbe, LK, 2006) |
" Urethane, a specific lung tumor carcinogen, can induce adenomas in mice." | 3.73 | Altered expression of connexins in urethane-induced mouse lung adenomas. ( Avanzo, JL; da Silva, TC; Dagli, ML; Fukumasu, H; Hernandez-Blazquez, FJ; Mesnil, M; Mori, CM; Yamasaki, H, 2006) |
"We studied the effect of endogenous immunoregulatory myelopeptide-2 on the development of spontaneous and urethane-induced lung adenomas." | 3.71 | Effect of myelopeptide-2 on the development of spontaneous and urethane-induced tumors in mice. ( Kirilina, EA; Mikhailova, AA; Morozova, OV; Turusov, VS, 2002) |
" injections of urethane (ethyl carbamate), each of 400 mg/kg body weight." | 3.70 | Chemoprevention by N-acetylcysteine of urethane-induced clastogenicity and lung tumors in mice. ( Balansky, RM; De Flora, S, 1998) |
"Four putative quantitative trait loci (QTLs) that influence susceptibility to the induction of lung adenomas by urethane in an F2 cross between A/J and BALB/cOlaHsd have been mapped." | 3.70 | At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice. ( Anna, CH; Devereux, TR; Festing, MF; Gao, F; Lin, L; Malkinson, AM; White, CM; Yang, A; You, M, 1998) |
"Susceptibility to urethane-induced lung adenomas in mice has a polygenic mode of inheritance, with no obvious discontinuity in lung tumour counts among 37 AXB recombinant inbred strains." | 3.69 | At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice. ( Festing, MF; Malkinson, AM; Yang, A, 1994) |
"In the A/J strain of mice, urethane (ethyl carbamate) induces lung hyperplasia, adenoma, and adenocarcinoma in a time-dependent manner." | 3.69 | Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. ( Chen, A; Horio, Y; Malkinson, AM; Rice, P; Roth, JA; Schrump, DS, 1996) |
"To determine if hemizygous transgenic mice carrying the human c-Ha-ras gene (CB6F1-Tg Hras2 mice (Hras2 mice)) are susceptible to the carcinogenic potential of known murine carcinogens, male and female Hras2 mice and their non-transgenic CB6F1 littermates (non-Tg mice) were each given a single intraperitoneal injection of 60 mg of vinyl carbamate (VC)/kg body weight or saline (vehicle control) and monitored for 16 wk without further treatment." | 3.69 | Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors. ( Hayashi, Y; Kodama, Y; Maronpot, RR; Mitsumori, K; Nomura, T; Wakana, S; Yamamoto, S; Yasuhara, K, 1997) |
"A number of investigators have observed a quadratic relationship between acute urethane dose and cumulative pulmonary adenoma incidence in mice." | 3.67 | Consideration of the mechanism of pulmonary adenogenesis in urethane-treated Swiss mice. ( O'Flaherty, EJ; Sichak, SP, 1984) |
" The ultrastructural characteristics, effect of dexamethasone on cellular morphology and proliferation rate, and the cytoskeletal protein pattern of NAL suggests that these cell strains may be related to a urethane-induced mouse lung adenoma cell strain NUL and to a metastasizing mouse lung tumour cell line CMT." | 3.67 | Establishment of epithelial cell strains from normal adult mouse lung resembling a urethane-induced lung adenoma cell strain and a metastasizing mouse lung carcinoma cell line. ( de Montfort, ML; Le Mesurier, SM; Lykke, AW; Smith, GJ, 1984) |
"To determine the locus in the H-2 complex that affects susceptibility to the development of pulmonary adenomas in mice, H-2 congenic and recombinant strains of mice with A/Wy, BALB/c, C3H, and B10 backgrounds were subjected to treatment with urethane." | 3.67 | The H-2 class II genes and the susceptibility to the development of pulmonary adenoma in mice. ( Migita, S; Miyashita, N; Moriwaki, K, 1989) |
"0 mg of urethane/g body wt the average diameter and prevalence of lung adenomas in adult strain." | 3.66 | Reduced prevalence and growth rate of urethane-induced lung adenomas in ageing adult strain A mice. ( Baxter, CS; Dourson, ML, 1981) |
"The combination of urethane and the non-steroidal oestrogen diethylstilboestrol induced lymphomas in CFLP mice." | 3.66 | Induction of lymphomas by urethane in combination with diethylstilboestrol in CFLP mice. ( Boján, F; Gomba, Sz; Rédai, I, 1979) |
" injection of caffeine (8, 20, and 40 mg/kg) 3 times weekly for 8 weeks suppressed the development of spontaneous pulmonary adenomas in strain A mice." | 3.66 | Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice. ( Shimkin, MB; Theiss, JC, 1978) |
" If BHT was given orally following injection of one single dose of urethane, adenoma formation in lung was enhanced." | 3.66 | Toxicity of butylated hydroxytoluene in mouse following oral administration. ( Lock, S; Witschi, H, 1978) |
"Transplacental exposure of BALB/c mice to urethane on day 17 of gestation resulted in the appearance of 2 distinct crops of primary lung tumors (adenomas)." | 3.66 | Two crops of primary lung tumors in BALB/c mice after a single transplacental exposure to urethane. ( Anderson, LM, 1978) |
"Lung adenomas arose in 2 of 10 nude mice injected twice with urethane in a dose of 1 mg/g of body weight; these tumours were revealed in 7 of 10 immunologically normal littermates treated in the same way." | 3.66 | [Lower urethane carcinogenicity for the lungs of thymus-free nude mice in comparison with immunologically normal littermate mice]. ( Gruntenko, EV; Kaledin, VI; Morozkova, TS, 1978) |
"Dextramycine as well as leftrotating isomer (chloramphenicol--levomycetin) diminished the blastomogenic effect of urethane which is known to induce lung adenomas in mice." | 3.65 | Dextramycine (the dextraisomer of chloramphenicol) as an inhibitor of the induction of lung adenomas in mice. ( Belitsky, GA; Bogush, TA; Konopleva, IA; Shabad, LM, 1977) |
"The effect of adhesive factor (AF), urethane and their combination on the mechanical properties of lung tissue (this effect was assessed by the nuclei isolation during a standard dispersion procedure) and on adenoma induction was studied." | 3.65 | [Effect of the tissue-specific lung adhesive factor on the urethane induction of pulmonary adenomas in mice]. ( Malenkov, AG; Modianova, EA; Shabad, LM, 1977) |
"Metaphase arrest by vincristine in urethane-induced murine pulmonary adenomas became linear after an interval of 60 min." | 3.65 | Cell kinetics of urethane-induced murine pulmonary adenomas: III. Implications of the disparity between the rates of entry into DNA synthesis and into mitosis. ( Dyson, P; Heppleston, AG, 1977) |
" In experiments described in the present paper we have investigated the influence of CP on the incidence of lung adenomas in mice after administration of urethane." | 3.65 | On the influence of chloramphenicol on the induction of lung adenomas by urethane in mice. ( Belitsky, GA; Bogush, TA; Shabad, LM, 1975) |
" Following these findings, the influence of hydantoin on carcinogenesis was evaluated by using the model of urethane-induced lung adenomas in SWR mice." | 3.65 | Hydantoin immunosuppression and carcinogenesis. ( Levo, Y; Markowitz, O; Trainin, N, 1975) |
"Continuous labelling of urethane induced pulmonary adenomata in adult male A2G mice at intervals up to 20 weeks showed that the growth fraction fell progressively from 18% at 7 weeks to 7% at 20 weeks." | 3.65 | Cell kinetics of urethane-induced murine pulmonary adenomata: II, the growth fraction and cell loss factor. ( Dyson, P; Heppleston, AG, 1976) |
"Thirty-six lung adenomata induced in mice by urethane followed or not by cortisone, all had an adenomatous morphology at first s." | 3.65 | Relationship between antigenicity and morphology of murine lung adenomata. ( Boiocchi, M; Colinaghi, MI; Ménard, S, 1976) |
" C strain females in the latter half of pregnancy were injected with urethane and the lungs of their young were searched for adenomas." | 3.63 | The neoplastic potentialities of mouse embryo tissues; lung adenomas in baby mice as result of prenatal exposure to urethane. ( ROUS, P; SMITH, WE, 1948) |
"Three spontaneous pulmonary adenomas of C mice, morphologically resembling those induced by methylcholanthrene or urethane, were propagated in host after host under conditions such that the neoplastic cells were directly exposed, while proliferating, to one or the other of these agents." | 3.63 | Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas. ( DUMBELL, K; ROUS, P, 1955) |
"Young, rapidly growing mice are greatly more responsive to the adenoma-inducing influence of urethane than are those just arriving at maturity." | 3.63 | Age of the host and other factors affecting the production with urethane of pulmonary adenomas in mice. ( ROGERS, S, 1951) |
"Lung cancer is one of the most common malignancies in the world, and chemotherapy can have unfavorable side effects." | 1.91 | The effect of Moringa oleifera leaf extracts against urethane-induced lung cancer in rat model. ( Abdel-Gaber, R; Dkhil, MA; Ibrahim, MA; Mohamed, SR; Soliman, D; Thagfan, FA, 2023) |
"Leptin is a nutritional cytokine, and it is closely related to the progression of cancer." | 1.91 | EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota. ( Gao, J; Hao, S; Jiang, P; Li, F, 2023) |
"Lung cancer is one of the most common types of malignant tumors of the respiratory system and has the highest rates of incidence and mortality of malignant tumors." | 1.72 | Synthesis and characterization of berberine-loaded chitosan nanoparticles for the protection of urethane-induced lung cancer. ( Abdel-Wahhab, MA; Badawy, AM; Badawy, EA; El-Bana, MA; El-Dosoky, MA; Farrag, AE; Mahmoud, MA; Morsy, SM, 2022) |
"Urethane was injected subcutaneously twice a week for 4 weeks to induce lung cancer and then the mice were fed for 4 months." | 1.72 | [Equol and its enantiomers inhibited urethane-induced lung cancer in mice]. ( Chen, ZK; Ma, DF; Wang, Y; Yu, X; Zou, YQ, 2022) |
"Aliskiren-treated mice had significantly lower levels of NF-κB p65, Bcl-2, cyclin D1, ICAM-1, MMP-2, and Nrf2, with an increase in the catalytic activity of caspase-3 due to its RAS inhibitory mechanism." | 1.72 | Novel therapeutic modalities target cell signaling of Renin-Angiotensin system/NF-κB-induced cell cycle arrest and apoptosis in urethane-induced lung cancer in mice: An in vivo study. ( Abo-Youssef, AM; Hamzawy, MA; Khalaf, MM; Malak, MN, 2022) |
"Trigonelline is a plant alkaloid, a significant constituent in coffee, and has shown health benefits in several disorders." | 1.72 | Multiple targets of Nrf 2 inhibitor; trigonelline in combating urethane-induced lung cancer by caspase-executioner apoptosis, cGMP and limitation of cyclin D1 and Bcl2. ( Abo-Youssef, AM; Hamzawy, MA; Khalaf, MM; Malak, MN, 2022) |
"Chemical induced carcinogenesis together with genetically engineered mouse models represent important approaches for the study of the complex mechanisms involving genotype and environmental factors in cancer development, including lung cancer." | 1.62 | Urethane-induced lung carcinogenesis. ( Del Prete, A; Schioppa, T; Sozio, F; Sozzani, S, 2021) |
"Lung cancer is the most common cancer and the leading cause of total deaths worldwide." | 1.51 | Liquid crystalline assembly for potential combinatorial chemo-herbal drug delivery to lung cancer cells. ( Abdelaziz, HM; Elzoghby, AO; Fang, JY; Freag, MS; Helmy, MW; Samaha, MW, 2019) |
"Lung cancer is one of the most lethal cancers and lacks effective treatment strategy." | 1.51 | A synergistic approach for management of lung carcinoma through folic acid functionalized co-therapy of capsaicin and gefitinib nanoparticles: Enhanced apoptosis and metalloproteinase-9 down-regulation. ( Arya, M; Kaithwas, G; Kanoujia, J; Parashar, P; Saraf, SA; Singh, M; Tripathi, CB; Yadav, A, 2019) |
"Thus, the tumor growth and metastasis were compared in WT and ApoE knockout (KO) mice." | 1.51 | Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity. ( Han, SB; Hong, JT; Kim, KC; Lee, YS; Yeo, IJ, 2019) |
"Lung cancer is the leading cause of cancer death worldwide." | 1.48 | Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis. ( Chawsheen, HA; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q, 2018) |
"Lung cancer is a deadly disease with increasing cases diagnosed worldwide and still a very poor prognosis." | 1.46 | Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation. ( Enguita, AB; Hernández, P; Lázaro, S; Martínez-Palacio, J; Oteo, M; Paramio, JM; Pérez-Crespo, M; Sage, J; Santos, M, 2017) |
"Urethane is a recognized genotoxic carcinogen in fermented foods and beverages." | 1.43 | Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016) |
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62." | 1.43 | The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016) |
"Our data validate chemical carcinogenesis as a suitable "in vivo" model for further and more detailed studies on the molecular mechanisms of the death response induced by Col V in lung infiltrating adenocarcinoma opening new strategies for treatment." | 1.43 | Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model. ( Alveno, RA; Capelozzi, VL; Corrêa, PY; de Morais, J; Fabro, AT; Faustino, CB; Parra, ER; Rangel, MP; Teodoro, WR; Vargas, CM; Velosa, AP, 2016) |
"Half of lung cancers are diagnosed in former smokers, leading to a significant treatment burden in this population." | 1.43 | Prostacyclin reverses the cigarette smoke-induced decrease in pulmonary Frizzled 9 expression through miR-31. ( Dwyer-Nield, LD; Keith, RL; McArthur, DG; Merrick, DT; New, ML; Tennis, MA, 2016) |
"Lung cancer is a common and highly frequent cause of cancer‑associated mortality worldwide." | 1.43 | Inflammation has a role in urethane‑induced lung cancer in C57BL/6J mice. ( Chen, T; Lian, X; Lin, X; Lu, L; Wei, S; Xu, C; Zhou, L, 2016) |
" Recent clinical data suggest that these different dosing schedules may adversely affect antigen-specific immunotherapy." | 1.42 | Assessing the Effects of Concurrent versus Sequential Cisplatin/Radiotherapy on Immune Status in Lung Tumor-Bearing C57BL/6 Mice. ( DeGregorio, MW; Griffey, SM; Kao, CJ; Lin, YC; Vang, DP; Wolf, M; Wurz, GT, 2015) |
"Curcumin has long been recognized as a chemopreventive agent, but poor bioavailability and weak Nrf2 induction have prohibited clinical application." | 1.42 | A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response. ( Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B, 2015) |
"LPS-induced pulmonary inflammation did not increase lung carcinogenesis, whereas decreased pulmonary inflammation by macrophage depletion promoted lung carcinogenesis." | 1.42 | The Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound Healing. ( Cao, N; Du, G; Duan, Y; Geng, S; Guo, Z; Han, G; Li, H; Liu, L; Ma, X; Zheng, Y, 2015) |
" PCA has been orally feed to urethane (ethyl carbamate) primed lung cancerous mice at a dosage of 100 mg/kg body weight for 30 consecutive days." | 1.40 | Antineoplastic and immunomodulatory effect of polyphenolic components of Achyranthes aspera (PCA) extract on urethane induced lung cancer in vivo. ( Kumar, A; Narayan, C, 2014) |
"During the carcinogenesis phase, no detectable Th1- or Th2-associated cytokine responses were observed, but levels of pro-inflammatory cytokines were increased with distinctive kinetics." | 1.39 | Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model. ( DeGregorio, MW; Greenberg, BE; Griffey, SM; Gutierrez, AM; Kao, CJ; Vang, DP; Wolf, M; Wurz, GT, 2013) |
"Urethane treatment induced 5 hyperplasias, 41 adenomas and 12 adenocarcinomas in the lungs of 8 A/J mice." | 1.39 | SPECT/CT of lung nodules using 111In-DOTA-c(RGDfK) in a mouse lung carcinogenesis model. ( Fujii, H; Hayakawa, T; Imai, T; Mutoh, M; Tsuta, K; Yanaka, A; Yoshimoto, M, 2013) |
"Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer." | 1.38 | The influence of physical activity in the progression of experimental lung cancer in mice. ( Cal, RN; Cordeiro, JA; Cury, PM; dos Santos, CH; Nagamine, KK; Neiva, CM; Paceli, RB, 2012) |
"Pretreatment with pterostilbene at 50 or 250 mg/kg significantly reduced tumor multiplicity by 26 and 49%, respectively." | 1.38 | Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy. ( Chen, RJ; Ho, CT; Ho, YS; Pan, MH; Tsai, SJ; Wang, YJ; Wu, CH, 2012) |
"Lung cancer is the leading cause of cancer-related death worldwide." | 1.38 | Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. ( Hayakawa, T; Imai, T; Imaida, K; Komiya, M; Mutoh, M; Takahashi, M; Tsuta, K; Ueno, T; Wakabayashi, K; Yanaka, A; Yoshimoto, M, 2012) |
"Urethane-treated animals showed 2." | 1.37 | Urban, traffic- related particles and lung tumors in urethane treated mice. ( Assunção, JV; Lemos, M; Mauad, T; Pereira, FA; Saldiva, PH, 2011) |
"Lung cancer is one of the most important avoidable causes of death around the world, the most widespread carcinoma, with a very poor prognosis, and is the leading cause of cancer death in both developed and developing countries." | 1.37 | Characterization of a murine lung adenocarcinoma (LAC1), a useful experimental model to study progression of lung cancer. ( Díaz, Mdel P; Eynard, AR; Ortiz, S; Piegari, M; Valentich, MA, 2011) |
"Lung inflammation was assessed after 1 week." | 1.37 | Neutralization of tumor necrosis factor bioactivity ameliorates urethane-induced pulmonary oncogenesis in mice. ( Kairi, CA; Kalomenidis, I; Karabela, SP; Magkouta, S; Moschos, C; Psallidas, I; Roussos, C; Stathopoulos, GT; Stathopoulos, I; Zakynthinos, SG, 2011) |
"When pioglitazone was administered beginning 8 weeks after the first carcinogen treatment when microscopic adenomas already existed, pioglitazone significantly inhibited tumor load (sum of tumor volume per lung in average) by 64% (P < 0." | 1.36 | Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. ( James, M; Lu, Y; Lubet, RA; Szabo, E; Wang, Y; Wen, W; You, M, 2010) |
"Urethane is a chemical carcinogen found in tobacco smoke that causes activating mutations in Kras and induces lung tumors in mice." | 1.35 | Overexpression of Sprouty 2 in mouse lung epithelium inhibits urethane-induced tumorigenesis. ( Miller, YE; Minowada, G, 2009) |
"Urethane is a chemical carcinogen which causes lung tumorigenesis in mice with similarities to human adenocarcinoma (AC)." | 1.35 | Lung tumor development in the presence of sphingosine 1-phosphate agonist FTY720. ( Bueno, V; Lopes, CT; Oshima, CT; Palma, PV; Salinas, NR, 2009) |
"Bexarotene has demonstrated chemopreventive and therapeutic efficacy towards mouse lung tumors." | 1.35 | Modulation by bexarotene of mRNA expression of genes in mouse lung tumors. ( Alyaqoub, FS; Liu, Y; Lubet, RA; Pereira, MA; Steele, VE; Tao, L, 2008) |
"Urethane is an established animal carcinogen and has been classified as "reasonably anticipated to be a human carcinogen." | 1.34 | Inhibition of urethane-induced carcinogenicity in cyp2e1-/- in comparison to cyp2e1+/+ mice. ( Ghanayem, BI, 2007) |
"Urethane treatment accelerated number and size of lung tumors developing in SOPten(flox/flox) mice of both ages." | 1.34 | Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. ( Hamada, K; Horie, Y; Kawahara, K; Kishimoto, H; Kubo, H; Mak, TW; Nakano, T; Nakazato, M; Nishio, M; Sasaki, M; Sasaki, T; Suzuki, A; Whitsett, JA; Yajima, N; Yanagi, S, 2007) |
"Bexarotene (Targretin), is a synthetic high-affinity RXR receptor agonist with limited affinity for RAR receptors." | 1.33 | Prevention of lung cancer progression by bexarotene in mouse models. ( Jia, D; Lubet, RA; Wang, D; Wang, Y; Yao, R; You, M; Zhang, Z, 2006) |
" Three experiments were performed: (i) a dose-response study with vinyl carbamate-induced tumors; (ii) a limited treatment study also with vinyl carbamate and (iii) prevention of NNK-induced tumors." | 1.33 | Prevention of mouse lung tumors by targretin. ( Alyaqoub, FS; Gunning, WT; Kramer, PM; Liu, Y; Lubet, RA; Nines, R; Pereira, MA; Steele, VE, 2006) |
"Melatonin treatment significantly lowered concentrations of MDA in blood-serum and catalase (blood-serum and lung) rather than in the lung bearing urethane-induced tumor." | 1.33 | [Melatonin inhibits urethane-induced carcinogenesis tumors in murine lung]. ( Anisimov, VN; Plotnikova, NA; Semenchenko, AV; Vesnushkin, GM, 2006) |
" Ten weekly ethyl carbamate (EC) doses caused a nearly 100% lung tumor incidence with a tumor multiplicity >2; multiple EC dosing is thus an alternative to the time-consuming transfer of transgenes and null mutations to susceptible backgrounds." | 1.32 | Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections. ( Dwyer-Nield, LD; Franklin, WA; Keith, RL; Le, M; Malkinson, AM; Miller, YE, 2003) |
"There was a higher risk of aneuploidy in the 6-months-of-air-pollution-exposure group (relative risk: 1." | 1.31 | Urban levels of air pollution modifies the progression of urethane-induced lung tumours in mice. ( Capelozzi, VL; Conceição, GM; Cury, PM; Lichtenfels, AJ; Reymão, MS; Saldiva, PH, 2000) |
"8 tumors/mouse due to the Pas1 allele dosage effect." | 1.31 | Cancer modifier alleles inhibiting lung tumorigenesis are common in inbred mouse strains. ( Acevedo, A; Dragani, TA; Galbiati, F; Giannì Barrera, R; Manenti, G; Noci, S; Salido, E, 2002) |
"These neoplasms are rare in mice and suggest endocrine dysfunction as a component of preconception carcinogenesis." | 1.30 | Preconception urethane or chromium(III) treatment of male mice: multiple neoplastic and non-neoplastic changes in offspring. ( Anderson, LM; Birely, L; Diwan, BA; Haines, DC; Kasprzak, KS; Riggs, CW; Sipowicz, MA; Yu, W, 1999) |
" Dose-response relationship and sequential changes in lung tumorigenesis induced by urethan in athymic mice were compared with those in euthymic littermates." | 1.29 | Comparison of lung tumorigenesis induced by urethan in athymic nude mice and euthymic littermates. ( Kobayashi, S; Noda, Y; Otsu, H, 1994) |
" The tumors with a clear dose-response relationship were lung tumor (alveolar/bronchiolar adenoma or carcinoma) and liver tumor (hemangioma or angiosarcoma)." | 1.28 | Quantitative risk assessment of carcinogenicity of urethane (ethyl carbamate) on the basis of long-term oral administration to B6C3F1 mice. ( Arihiro, K; Inai, K; Khatun, N; Nishisaka, T; Tachiyama, Y; Takeshima, Y; Yonehara, S, 1991) |
"Urethane produced an increase in pulmonary tumor response in this study in agreement with previous investigations." | 1.28 | Pulmonary adenomas in A/J mice treated with silica. ( Chrisp, CE; Fisher, GL; McNeill, DA, 1990) |
" This hypothesis was tested directly by chronic administration of BHT, BHT-BuOH, and two other metabolites, 2,6-di-tert-butyl-4-hydroxymethyl phenol and 2,6-di-tert-butyl-1,4-benzoquinone to MA/MyJ mice following a single injection of urethane." | 1.28 | A metabolite of butylated hydroxytoluene with potent tumor-promoting activity in mouse lung. ( Fernandez, CA; Malkinson, AM; Schullek, KM; Thompson, JA, 1989) |
"When urethane was given to F1 offspring of parents that had been irradiated with 216 rad of X-rays, a large number of offspring (18." | 1.27 | X-ray-induced germ-line mutation leading to tumors. Its manifestation in mice given urethane post-natally. ( Nomura, T, 1983) |
"N-Nitrosocimetidine (NCM) is a nitrosation product of cimetidine, a commonly-prescribed pharmaceutical agent." | 1.27 | N-nitrosocimetidine as a modifier of chemically-initiated tumors in mice. ( Anderson, LM; Giner-Sorolla, A; Hagiwara, A; Kovatch, RM; Rehm, S; Rice, JM; Riggs, CW, 1988) |
"Vinyl carbamate (VC) is a suspect metabolic intermediate in ethyl carbamate (EC) carcinogenesis." | 1.27 | Tumorigenesis and genotoxicity of ethyl carbamate and vinyl carbamate in rodent cells. ( Allen, JW; Backer, LC; Campbell, JA; Hatch, GG; Nesnow, S; Pereira, MA; Sharief, Y; Stead, AG; Stoner, GD, 1986) |
"The first group showed squamous cell carcinomas in the nasal cavity (4 out of 10 mice), trachea (4 out of 10 mice) and lung (2 out of 10 mice)." | 1.27 | Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice. ( Ide, G; Iwasaki, I; Takahashi, A, 1985) |
" The results support the common assumption that tumor growth rate is independent of the rate of chronic administration of a carcinogen." | 1.26 | Relationship of lung adenoma prevalence and growth rate to acute urethan dose and target cell number. ( Dourson, ML; O'Flaherty, EJ, 1982) |
" This inverse dose-response relationship mimics the previously reported effect of 5-methyl cytidine on mammary tumour growth in C3H mice." | 1.26 | Inhibition of urethan induced lung tumour growth in strain A mice by 5-methyl cytidine. ( Theiss, JC, 1980) |
"cell transfer, and also the generalized malignant lymphomas induced by inoculation of filtered extracts contained C-type virus particles." | 1.26 | C-type virus particles in urethan-induced pulmonary and renal carcinomas, in cell-graft-transmitted carcinosarcomas, and in filtrate-induced lymphomas in mice. ( Dreyfuss, Y; Ehrenreich, T; Feldman, D; Gross, L; Moore, LA, 1976) |
"Urethane was found to be uniformly distributed in all the major organs of foetal, young and adult ICR/Jcl mice and then to disappear rapidly as measured by the incorporation of urethane-carbonyl-14C, thus permitting the accurate comparison of tumour susceptibility of cells in various organs of mice at different ages." | 1.26 | Comparison of tumour susceptibility among various organs of foetal, young and adult ICR/Jcl mice. ( Nomura, T, 1976) |
"Urethane treated SWR mice received 6 fortnightly injections of lymphocytes sensitized in vitro against syngeneic fibroblasts." | 1.25 | Increased incidence of urethane induced lung adenomata by autosensitized lymphocytes. ( Carnaud, C; Cohen, IR; Levo, Y; Trainin, N, 1974) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 336 (55.45) | 18.7374 |
1990's | 65 (10.73) | 18.2507 |
2000's | 89 (14.69) | 29.6817 |
2010's | 91 (15.02) | 24.3611 |
2020's | 25 (4.13) | 2.80 |
Authors | Studies |
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Mahmoud, MA | 1 |
El-Bana, MA | 1 |
Morsy, SM | 1 |
Badawy, EA | 1 |
Farrag, AE | 1 |
Badawy, AM | 1 |
Abdel-Wahhab, MA | 1 |
El-Dosoky, MA | 1 |
Yu, X | 1 |
Zou, YQ | 1 |
Wang, Y | 12 |
Chen, ZK | 1 |
Ma, DF | 1 |
Li, S | 3 |
Counter, CM | 5 |
Satoh, H | 3 |
Arai, Y | 1 |
Furukawa, E | 1 |
Moriguchi, T | 3 |
Hama, N | 1 |
Urushidate, T | 1 |
Totoki, Y | 1 |
Kato, M | 1 |
Ohe, Y | 1 |
Yamamoto, M | 4 |
Shibata, T | 2 |
Khalaf, MM | 2 |
Abo-Youssef, AM | 3 |
Malak, MN | 2 |
Hamzawy, MA | 3 |
Dwyer-Nield, L | 2 |
Keith, RL | 3 |
Tennis, MA | 2 |
Ibrahim, MA | 1 |
Mohamed, SR | 1 |
Dkhil, MA | 1 |
Thagfan, FA | 1 |
Abdel-Gaber, R | 1 |
Soliman, D | 1 |
Sahyon, HA | 1 |
El-Shafai, NM | 1 |
Elnajjar, N | 1 |
Althobaiti, F | 1 |
Aldhahrani, A | 1 |
Alharbi, NS | 1 |
Shoair, AGF | 1 |
El-Mehasseb, IM | 1 |
Abdel-Fattah, MM | 1 |
Mohamed, WR | 1 |
Hassanein, EHM | 1 |
Arab, HA | 1 |
Arafa, EA | 1 |
Li, F | 1 |
Hao, S | 1 |
Gao, J | 1 |
Jiang, P | 1 |
Fang, G | 1 |
Wang, S | 2 |
Chen, Q | 2 |
Luo, H | 1 |
Lian, X | 3 |
Shi, D | 1 |
Yang, X | 1 |
Zhang, Y | 3 |
Huang, Y | 1 |
Qi, X | 1 |
Su, T | 1 |
Lu, L | 3 |
Wang, Q | 1 |
Zhang, T | 1 |
Chang, X | 1 |
Wang, K | 1 |
Lee, MH | 1 |
Ma, WY | 1 |
Liu, K | 1 |
Dong, Z | 1 |
Shibata, MA | 1 |
Shibata, E | 1 |
Morimoto, J | 1 |
Kondo, Y | 1 |
Sun, F | 3 |
Guo, ZS | 1 |
Gregory, AD | 1 |
Shapiro, SD | 3 |
Xiao, G | 3 |
Qu, Z | 3 |
Han, X | 1 |
Liu, X | 3 |
Wang, X | 2 |
Guo, W | 1 |
Wen, Y | 1 |
Meng, W | 1 |
Peng, D | 1 |
Lv, P | 1 |
Zhang, X | 4 |
Shen, H | 1 |
Zhang, HJ | 1 |
Chang, WJ | 1 |
Jia, CY | 1 |
Qiao, L | 1 |
Zhou, J | 3 |
Zheng, XW | 1 |
Zhang, JH | 1 |
Li, HC | 1 |
Yang, ZY | 1 |
Liu, ZH | 1 |
Liu, GC | 1 |
Ji, SP | 1 |
Lu, F | 1 |
Lee, YS | 4 |
Lee, JY | 1 |
Song, SH | 1 |
Kim, DM | 1 |
Lee, JW | 1 |
Chi, XZ | 2 |
Ito, Y | 2 |
Bae, SC | 2 |
Radwan, E | 1 |
Ali, M | 1 |
Faied, SMA | 1 |
Omar, HM | 1 |
Mohamed, WS | 1 |
Abd-Elghaffar, SK | 1 |
Sayed, AA | 1 |
Zheng, J | 2 |
Guo, X | 1 |
Nakamura, Y | 1 |
Zhou, X | 1 |
Yamaguchi, R | 1 |
Zhang, J | 1 |
Ishigaki, Y | 1 |
Uramoto, H | 1 |
Yamada, S | 1 |
Sozio, F | 1 |
Schioppa, T | 1 |
Sozzani, S | 1 |
Del Prete, A | 1 |
Li, K | 1 |
Zheng, X | 1 |
Tang, H | 3 |
Zang, YS | 1 |
Zeng, C | 1 |
Shen, Y | 1 |
Pang, Y | 1 |
Xie, F | 1 |
Lu, X | 1 |
Luo, Y | 1 |
Li, Z | 4 |
Bi, W | 1 |
Jia, X | 1 |
Huang, T | 1 |
Wei, R | 1 |
Huang, K | 1 |
Chen, Z | 1 |
Zhu, Q | 1 |
He, Y | 1 |
Zhang, M | 2 |
Gu, Z | 1 |
Xiao, Y | 2 |
Fletcher, JA | 1 |
Kimura, A | 1 |
Utsumi, S | 1 |
Shimokawa, A | 1 |
Nishimori, R | 1 |
Stewart, NJ | 1 |
Kamada, Y | 1 |
Imai, H | 1 |
Fujiwara, H | 1 |
Chen, T | 2 |
Xu, C | 2 |
Lin, X | 3 |
Leung, YK | 1 |
Ho, SM | 1 |
Ruan, XZ | 1 |
Liu, C | 2 |
Liao, Y | 3 |
Fan, S | 2 |
Fu, X | 1 |
Xiong, J | 2 |
Zhou, S | 3 |
Zou, M | 2 |
Wang, J | 2 |
Gobbini, E | 1 |
Pilotto, S | 1 |
Pasello, G | 1 |
Polo, V | 1 |
Di Maio, M | 1 |
Arizio, F | 1 |
Galetta, D | 1 |
Petrillo, P | 1 |
Chiari, R | 1 |
Matocci, R | 1 |
Di Costanzo, A | 1 |
Di Stefano, TS | 1 |
Aglietta, M | 1 |
Cagnazzo, C | 1 |
Sperduti, I | 1 |
Bria, E | 1 |
Novello, S | 1 |
Mishra, M | 1 |
Jiang, H | 1 |
Chawsheen, HA | 1 |
Gerard, M | 1 |
Toledano, MB | 1 |
Wei, Q | 1 |
Champeris Tsaniras, S | 2 |
Villiou, M | 1 |
Giannou, AD | 2 |
Nikou, S | 1 |
Petropoulos, M | 1 |
Pateras, IS | 1 |
Tserou, P | 1 |
Karousi, F | 1 |
Lalioti, ME | 1 |
Gorgoulis, VG | 1 |
Patmanidi, AL | 1 |
Stathopoulos, GT | 7 |
Bravou, V | 1 |
Lygerou, Z | 1 |
Taraviras, S | 2 |
Yao, J | 1 |
Du, Z | 2 |
Zhang, S | 2 |
Lin, Y | 2 |
Li, H | 3 |
Zhou, L | 4 |
Yan, G | 2 |
Wu, X | 1 |
Duan, Y | 5 |
Du, G | 6 |
Parashar, P | 3 |
Tripathi, CB | 3 |
Arya, M | 3 |
Kanoujia, J | 3 |
Singh, M | 3 |
Yadav, A | 3 |
Saraf, SA | 3 |
Kumar, A | 2 |
Guleria, A | 1 |
Zhou, H | 1 |
Saliba, J | 1 |
Sandusky, GE | 1 |
Sears, CR | 1 |
Abdelaziz, HM | 1 |
Elzoghby, AO | 1 |
Helmy, MW | 1 |
Samaha, MW | 1 |
Fang, JY | 1 |
Freag, MS | 1 |
Kaithwas, G | 1 |
Kanellakis, NI | 1 |
Pepe, MAA | 1 |
Agalioti, T | 1 |
Zazara, DE | 1 |
Giopanou, I | 1 |
Psallidas, I | 2 |
Spella, M | 1 |
Marazioti, A | 1 |
Arendt, KAM | 1 |
Lamort, AS | 1 |
Papadaki, H | 1 |
Lilis, I | 1 |
Wang, M | 4 |
Lin, H | 3 |
Tong, Q | 1 |
Yeo, IJ | 1 |
Kim, KC | 1 |
Han, SB | 3 |
Hong, JT | 3 |
Sato, A | 1 |
Yamada, N | 1 |
Ogawa, Y | 1 |
Ikegami, M | 1 |
Wurz, GT | 2 |
Gutierrez, AM | 1 |
Greenberg, BE | 1 |
Vang, DP | 2 |
Griffey, SM | 2 |
Kao, CJ | 2 |
Wolf, M | 2 |
DeGregorio, MW | 2 |
Dassano, A | 1 |
Noci, S | 2 |
Galbiati, F | 4 |
Colombo, F | 2 |
Trincucci, G | 2 |
Pettinicchio, A | 3 |
Dragani, TA | 9 |
Manenti, G | 7 |
Fanjul-Fernández, M | 1 |
Folgueras, AR | 1 |
Fueyo, A | 1 |
Balbín, M | 1 |
Suárez, MF | 1 |
Fernández-García, MS | 1 |
Freije, JMP | 1 |
López-Otín, C | 1 |
Popovich, IG | 2 |
Piskunova, TS | 1 |
Tyndyk, ML | 1 |
Anikin, IV | 1 |
Zabezhinskiĭ, MA | 2 |
Anisimov, VN | 5 |
Hayakawa, T | 2 |
Mutoh, M | 3 |
Imai, T | 2 |
Tsuta, K | 2 |
Yanaka, A | 2 |
Fujii, H | 1 |
Yoshimoto, M | 2 |
Takai, J | 1 |
Ebina, M | 3 |
Sun, T | 2 |
Li, J | 2 |
Liu, W | 1 |
Zhao, B | 1 |
Liu, Y | 4 |
Li, X | 1 |
Wu, J | 1 |
Li, Y | 2 |
Yang, T | 1 |
Hu, G | 1 |
Dai, J | 1 |
Yang, Q | 1 |
Dai, L | 1 |
Jiang, Y | 1 |
Teixeira, D | 1 |
Almeida, JS | 1 |
Visniauskas, B | 1 |
Gomes, GN | 1 |
Hirata, AE | 1 |
Bueno, V | 5 |
Nakahara, SB | 1 |
Sanches, DS | 1 |
Caniceiro, BD | 1 |
Wysochi, HL | 1 |
da Silva, GB | 1 |
Latorre, AO | 1 |
Narayan, C | 1 |
Jan Treda, C | 1 |
Fukuhara, T | 1 |
Suzuki, T | 1 |
Nakamura, A | 1 |
Zaini, J | 1 |
Kikuchi, T | 1 |
Nukiwa, T | 1 |
Pandey, M | 3 |
Sultana, S | 2 |
Gupta, KP | 3 |
Sahay, S | 1 |
Tiwari, P | 1 |
Upadhyay, DS | 1 |
Yan, S | 1 |
Whitsett, JA | 3 |
Westcott, PM | 2 |
Halliwill, KD | 1 |
To, MD | 4 |
Rashid, M | 1 |
Rust, AG | 1 |
Keane, TM | 1 |
Delrosario, R | 1 |
Jen, KY | 1 |
Gurley, KE | 3 |
Kemp, CJ | 4 |
Fredlund, E | 1 |
Quigley, DA | 1 |
Adams, DJ | 1 |
Balmain, A | 4 |
Huang, L | 1 |
Carney, J | 1 |
Cardona, DM | 1 |
Pershing, NL | 1 |
Lampson, BL | 1 |
Belsky, JA | 1 |
Kaltenbrun, E | 1 |
MacAlpine, DM | 1 |
Yun, HM | 1 |
Park, KR | 1 |
Park, MH | 1 |
Kim, DH | 2 |
Jo, MR | 1 |
Kim, JY | 1 |
Kim, EC | 1 |
Yoon, DY | 1 |
Lin, YC | 1 |
Zhang, C | 1 |
Chen, G | 1 |
Xu, L | 1 |
Liu, Z | 1 |
Fu, S | 1 |
Yu, L | 2 |
Jiang, Z | 1 |
Zhou, B | 2 |
Shen, T | 1 |
Jiang, T | 1 |
Long, M | 1 |
Chen, J | 1 |
Ren, DM | 1 |
Wong, PK | 1 |
Chapman, E | 1 |
Zhang, DD | 1 |
Colombo, NB | 1 |
Rangel, MP | 2 |
Martins, V | 1 |
Hage, M | 1 |
Gelain, DP | 1 |
Barbeiro, DF | 1 |
Grisolia, CK | 1 |
Parra, ER | 3 |
Capelozzi, VL | 5 |
Burns, TF | 1 |
Stabile, LP | 1 |
Siegfried, JM | 1 |
Moser, RD | 1 |
Morozkova, TS | 2 |
Kaledin, VI | 3 |
Ma, X | 3 |
Deng, J | 1 |
Cao, N | 4 |
Guo, Z | 3 |
Zheng, Y | 3 |
Geng, S | 3 |
Meng, M | 2 |
Tsuji, S | 1 |
Kuwahara, Y | 1 |
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Mariano, JM | 2 |
De Flora, S | 3 |
Boucher, K | 1 |
Kolesnichenko, TS | 10 |
Antoshina, EE | 2 |
Mori, I | 3 |
Hayashi, S | 1 |
Shimo, T | 1 |
Onodera, H | 2 |
Cattanach, BM | 1 |
Papworth, D | 1 |
Patrick, G | 1 |
Goodhead, DT | 1 |
Hacker, T | 1 |
Cobb, L | 1 |
Whitehill, E | 1 |
Lin, L | 1 |
Gao, F | 1 |
Anna, CH | 1 |
White, CM | 1 |
Nagashima, Y | 1 |
Yajima, S | 2 |
Horikawa, S | 1 |
Kishimoto, M | 1 |
Hagemann, G | 1 |
Morawietz, G | 1 |
Fernandez, P | 1 |
Yu, W | 1 |
Sipowicz, MA | 1 |
Haines, DC | 1 |
Birely, L | 1 |
Riggs, CW | 2 |
Kasprzak, KS | 1 |
Umemura, T | 1 |
Hioki, K | 1 |
Inoue, T | 2 |
Kurokawa, Y | 1 |
Timofeeva, OA | 1 |
Filipenko, ML | 1 |
Kalina, M | 1 |
Shannon, JM | 1 |
Imianitov, EN | 1 |
Togo, AV | 1 |
Dong, Q | 1 |
Xiao, B | 1 |
Hayashi, SM | 2 |
Nonoyama, T | 2 |
Jiang, YG | 1 |
Chen, JK | 1 |
Wu, ZL | 1 |
Leyton, J | 1 |
Zia, F | 1 |
Tuthill, C | 1 |
Badamchian, M | 1 |
Goldstein, AL | 1 |
Lee, K | 1 |
Johnson, VJ | 1 |
Kumadaki, I | 1 |
D'Agostini, F | 1 |
Camoirano, A | 1 |
Wakefield, LM | 2 |
Abujiang, P | 1 |
Thompson, JA | 2 |
Carlson, TJ | 1 |
Sun, Y | 1 |
Yanai, T | 1 |
Masegi, T | 1 |
Ohno, J | 1 |
Sekido, Y | 1 |
Hasegawa, Y | 1 |
Nishizawa , J | 1 |
Saito, H | 1 |
Ishikawa, F | 1 |
Shimokata, K | 1 |
Salvador, AF | 1 |
Muñoz, SE | 1 |
Burstein, NA | 1 |
McIntire, KR | 1 |
Allison, AC | 1 |
Koujitani, T | 1 |
Tamura, T | 1 |
Takizawa, T | 1 |
McKenna, IM | 1 |
Ramakrishna, G | 1 |
Shiao, YH | 1 |
Powell, DA | 1 |
Saran, A | 1 |
Zaffaroni, D | 1 |
Pazzaglia, S | 1 |
Peissel, B | 1 |
Spinola, M | 1 |
Zanesi, N | 1 |
Rebessi, S | 1 |
Mancuso, MT | 1 |
Covelli, V | 1 |
Malkinson, A | 1 |
Radcliffe, R | 1 |
Bauer, A | 1 |
Kleeberger, S | 1 |
Giannì Barrera, R | 1 |
Salido, E | 1 |
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De Souza, P | 1 |
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Kikkawa, Y | 1 |
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Gross, L | 1 |
Feldman, D | 1 |
Dreyfuss, Y | 1 |
Ehrenreich, T | 1 |
Moore, LA | 1 |
Gunderson, TJ | 1 |
McSwigan, CE | 1 |
Whittemore, AS | 1 |
Sula, J | 1 |
Rédai, I | 1 |
Gomba, Sz | 1 |
Kawai, T | 1 |
Umezawa, I | 1 |
Komiyama, K | 1 |
Kawakubo, Y | 1 |
Nishiyama, Y | 1 |
Hata, T | 1 |
Lock, S | 3 |
Karmali, RA | 1 |
Horrobin, DF | 1 |
Good, RA | 1 |
Gruntenko, EV | 1 |
Nagy, A | 1 |
Herman, K | 1 |
Hadden, JW | 1 |
Balanski, RM | 2 |
Dzhioev, FK | 4 |
Williamson, D | 1 |
Brightwell, J | 2 |
Shabad, LM | 9 |
Bogush, TA | 2 |
Konopleva, IA | 1 |
Belitsky, GA | 2 |
Modianova, EA | 3 |
Malenkov, AG | 1 |
Dyson, P | 3 |
Jones, HB | 2 |
Grendon, A | 2 |
Takemoto, K | 1 |
Katayama, H | 1 |
Maruyama, T | 1 |
Komatsu, Y | 1 |
Bhide, SV | 1 |
Sirsat, MV | 1 |
Levo, Y | 3 |
Markowitz, O | 1 |
Snyder, F | 2 |
Malone, B | 2 |
Ménard, S | 3 |
Colinaghi, MI | 1 |
Boiocchi, M | 1 |
Troxell, MC | 1 |
Thompson, TL | 1 |
Terry, LS | 1 |
Neeper-Bradley, TL | 1 |
Conner, MK | 1 |
Seo, JS | 1 |
Chung, HT | 1 |
Cho, KJ | 1 |
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Gagnon, JM | 1 |
Rousseaux, CG | 1 |
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Borrello, MG | 1 |
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Ohmori, H | 1 |
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Murakami, T | 1 |
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Kuroiwa, A | 1 |
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Grunow, W | 1 |
Iversen, OH | 1 |
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Tachiyama, Y | 1 |
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Munson, L | 1 |
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Masuyama, T | 1 |
Tanaka, S | 1 |
Kurokawa, N | 1 |
Isa, Y | 2 |
Kristiansen, E | 2 |
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Knudsen, I | 1 |
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Bentel, JM | 2 |
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Nuzum, EO | 2 |
Hanson, LA | 1 |
Nagahara, N | 1 |
Kitamura, H | 1 |
Ogawa, T | 1 |
Ito, T | 1 |
Kanisawa, M | 1 |
Heinrich, U | 1 |
Pott, F | 1 |
Rittinghausen, S | 1 |
Steele, JG | 1 |
Loo, CK | 1 |
Jiang, TL | 1 |
Yan, SC | 1 |
Zhao, LF | 1 |
Collins, TF | 1 |
Sotomayor, RE | 1 |
Schullek, KM | 1 |
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Yokota, K | 1 |
Hattori, A | 1 |
Kunz, HW | 1 |
Gill, TJ | 1 |
Shinozuka, H | 1 |
Miyashita, N | 2 |
Moriwaki, K | 2 |
Migita, S | 1 |
Rhodes, GC | 1 |
Moore, GP | 1 |
Hasegawa, C | 1 |
Field, KJ | 1 |
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Hagiwara, A | 1 |
Giner-Sorolla, A | 1 |
Kovatch, RM | 1 |
Rehm, S | 1 |
Rice, JM | 1 |
Agassy-Cahalon, L | 1 |
Smorodinsky, NI | 1 |
Vorobtsova, IE | 1 |
Kitaev, EM | 1 |
Eriguchi, N | 1 |
Hara, H | 1 |
Yoshida, H | 1 |
Nishida, H | 1 |
Nakayama, T | 1 |
Ohishi, K | 1 |
Tsuda, H | 1 |
Inoue, S | 1 |
Ikeda, I | 1 |
Endo, A | 1 |
Last, JA | 1 |
Warren, DL | 1 |
Pecquet-Goad, E | 1 |
Thaete, LG | 3 |
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Oh, YR | 1 |
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Kim, YJ | 1 |
Burkhard, W | 1 |
Fritz-Niggli, H | 1 |
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Vezeridis, MP | 1 |
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Backer, LC | 1 |
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Astengo, M | 1 |
Serra, D | 1 |
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Superczynski, MJ | 1 |
Nesbitt, MN | 1 |
Skamene, E | 1 |
Takahashi, A | 1 |
Iwasaki, I | 1 |
Ide, G | 1 |
Lindenschmidt, RC | 1 |
Tryka, AF | 1 |
Ribacchi, R | 6 |
Carnaud, C | 1 |
Cohen, IR | 1 |
Gori, GB | 1 |
Ganter, P | 1 |
Maral, R | 1 |
Lespagnol, A | 1 |
Druckrey, H | 1 |
Ivankovic, S | 1 |
Bücheler, J | 1 |
Preussmann, R | 1 |
Sacquet, E | 1 |
Puvion, F | 1 |
Vlaeminck, MN | 2 |
Pluot, M | 1 |
Hopfner, C | 1 |
Adnet, JJ | 1 |
Caulet, T | 1 |
Vesselinovitch, SD | 6 |
Mihailovich, N | 6 |
Pietra, G | 1 |
Hollander, CF | 1 |
Bentvelzen, P | 1 |
Stromskaia, TP | 1 |
Pogosiants, EE | 2 |
Sokova, OI | 1 |
Prigozhina, EL | 1 |
Liebelt, A | 1 |
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Frei, JV | 1 |
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Rao, KV | 1 |
Smetanin, EY | 1 |
Pitsin, DG | 1 |
Kagan, GY | 1 |
Postnikova, ZA | 1 |
Morgunova, TD | 1 |
Rakovskay, IV | 1 |
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Frolov, AF | 2 |
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12 reviews available for urethane and Lung Neoplasms
Article | Year |
---|---|
Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate.
Topics: Allyl Compounds; Animals; Carcinogens, Environmental; DNA Adducts; Humans; Lung Neoplasms; Metabolic | 2010 |
[Vertical transmission of cancer promoting factors].
Topics: Animals; Female; Germ Cells; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Mutation; Neoplasms; Neop | 1984 |
Polygenic resistance to mouse pulmonary adenomas.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chromosomes, Huma | 2000 |
Quantitative theories of oncogenesis.
Topics: Adult; Age Factors; Aged; Animals; Carcinogens; Cell Division; Cell Survival; Cell Transformation, N | 1978 |
Experimental data concerning the question of the synergic action of the influenza virus and of some chemical carcinogens in the pathogenesis of lung cancer.
Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Humans; Influenza, Human; Lung Neoplasms | 1979 |
Genetic studies on lung tumor susceptibility and histogenesis in mice.
Topics: Alleles; Animals; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Cystadenoma; Genes, ras | 1991 |
Carcinogenesis of foods.
Topics: Animals; Carcinogens; Cooking; Dietary Fiber; Ethanol; Female; Food Contamination; Gastrointestinal | 1990 |
Developmental toxicity of urethan.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cells, Cultured; Cricetinae; Embryonic and F | 1989 |
Hazards of urethane (ethyl carbamate): a review of the literature.
Topics: Adenoma; Anesthesia; Animals; Chemistry; Female; History, 20th Century; Humans; Lung Neoplasms; Mate | 1988 |
The carcinogenic action and metabolism of urethan and N-hydroxyurethan.
Topics: Adenoma; Animals; Animals, Newborn; Body Fluids; Breast Neoplasms; Carbamates; Carcinogens; Carcinom | 1968 |
More about isonicotinic acid hydrazide toxicity.
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma; Chemical and Drug Induced Liver Injury; C | 1970 |
A critical review of experiments in chemical carcinogensis using newborn animals.
Topics: Age Factors; Animals; Animals, Newborn; Anthracenes; Benz(a)Anthracenes; Carcinogens; Cricetinae; Ha | 1968 |
594 other studies available for urethane and Lung Neoplasms
Article | Year |
---|---|
Synthesis and characterization of berberine-loaded chitosan nanoparticles for the protection of urethane-induced lung cancer.
Topics: Animals; bcl-2-Associated X Protein; Berberine; Caspase 9; Chitosan; Lung Neoplasms; Male; Mice; Nan | 2022 |
[Equol and its enantiomers inhibited urethane-induced lung cancer in mice].
Topics: Animals; Body Weight; Equol; Genistein; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; NF-E2-Relate | 2022 |
Non-canonical genomic driver mutations of urethane carcinogenesis.
Topics: Animals; Carcinogenesis; Carcinogens; Genomics; Lung Neoplasms; Mice; Mutation; Nucleotides; Proto-O | 2022 |
Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels.
Topics: Animals; Carcinogenesis; Disease Models, Animal; Genomics; Humans; Kelch-Like ECH-Associated Protein | 2022 |
Novel therapeutic modalities target cell signaling of Renin-Angiotensin system/NF-κB-induced cell cycle arrest and apoptosis in urethane-induced lung cancer in mice: An in vivo study.
Topics: Amides; Animals; Apoptosis; Carboplatin; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Cycle Check | 2022 |
Protocol for intranasal chemoprevention delivery in a urethane mouse lung cancer model.
Topics: Animals; Carcinogens; Chemoprevention; Disease Models, Animal; Enzyme Inhibitors; Iloprost; Lung Neo | 2022 |
The effect of Moringa oleifera leaf extracts against urethane-induced lung cancer in rat model.
Topics: Animals; Collagen; Lung Neoplasms; Moringa oleifera; Oxidative Stress; Plant Extracts; Plant Leaves; | 2023 |
Multiple targets of Nrf 2 inhibitor; trigonelline in combating urethane-induced lung cancer by caspase-executioner apoptosis, cGMP and limitation of cyclin D1 and Bcl2.
Topics: Alkaloids; Animals; Apoptosis; Caspases; Cyclin D1; Enzyme Inhibitors; Lung Neoplasms; Mice; Mice, I | 2022 |
Avocado peel extract loaded on chitosan nanoparticles alleviates urethane toxicity that causes lung cancer in a mouse model.
Topics: Animals; Chitosan; Humans; Lung Neoplasms; Mice; Nanoparticles; Persea; Plant Extracts; Urethane | 2023 |
Role of NF-κB/ICAM-1, JAK/STAT-3, and apoptosis signaling in the anticancer effect of tangeretin against urethane-induced lung cancer in BALB/c mice.
Topics: Animals; Apoptosis; Caspase 3; Intercellular Adhesion Molecule-1; Lung Neoplasms; Mice; Mice, Inbred | 2023 |
EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota.
Topics: Animals; Carcinogenesis; Diet, High-Fat; Gastrointestinal Microbiome; Leptin; Lung; Lung Neoplasms; | 2023 |
Time-restricted feeding affects the fecal microbiome metabolome and its diurnal oscillations in lung cancer mice.
Topics: Animals; Feces; Lung Neoplasms; Metabolome; Mice; Mice, Inbred C57BL; Mice, Nude; Microbiota; RNA, R | 2023 |
Evodiamine suppresses Notch3 signaling in lung tumorigenesis via direct binding to γ-secretases.
Topics: A549 Cells; Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Phytogenic; Carcin | 2020 |
Targeting Opsin4/Melanopsin with a Novel Small Molecule Suppresses PKC/RAF/MEK/ERK Signaling and Inhibits Lung Adenocarcinoma Progression.
Topics: A549 Cells; Adenocarcinoma of Lung; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell | 2020 |
Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Female; Genes, Dominant; Lung Neoplasms; Mam | 2020 |
Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer.
Topics: Animals; Antineoplastic Agents, Immunological; Cell Line, Tumor; Combined Modality Therapy; Female; | 2020 |
TNF-α-dependent lung inflammation upregulates superoxide dismutase-2 to promote tumor cell proliferation in lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cytokines; Female; Huma | 2020 |
Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway.
Topics: A549 Cells; Adenocarcinoma of Lung; Animals; beta Catenin; Cell Line, Tumor; Cell Movement; Cell Pro | 2020 |
Topics: Adenocarcinoma of Lung; Animals; Core Binding Factor Alpha 3 Subunit; Gene Expression Regulation, Ne | 2020 |
Novel therapeutic regimens for urethane-induced early lung cancer in rats: Combined cisplatin nanoparticles with vitamin-D
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cholecalciferol; Cisplatin; Disease Models, | 2021 |
Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane-Induced Lung Tumorigenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Humans; Interleukin-1beta; Lung Neoplasms; M | 2020 |
Urethane-induced lung carcinogenesis.
Topics: Animals; Carcinogenesis; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Urethane | 2021 |
Signaling levels mold the RAS mutation tropism of urethane.
Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; Genes, ras; Lung Neoplasms; Mice; Mice, 12 | 2021 |
E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
Topics: Amino Acid Sequence; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell | 2021 |
Inflammation during Lung Cancer Progression and Ethyl Pyruvate Treatment Observed by Pulmonary Functional Hyperpolarized
Topics: Animals; Carcinogens; Inflammation; Lung Neoplasms; Magnetic Resonance Imaging; Male; Mice; Pyruvate | 2021 |
Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cholesterol; Diet, Atherogenic; Gene Expr | 2017 |
G-Protein-Coupled Estrogen Receptor Antagonist G15 Decreases Estrogen-Induced Development of Non-Small Cell Lung Cancer.
Topics: A549 Cells; Adenocarcinoma; Animals; Benzodioxoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor | 2019 |
Effect of Contract Research Organization Bureaucracy in Clinical Trial Management: A Model From Lung Cancer.
Topics: Academies and Institutes; Clinical Trials as Topic; Contract Services; Financial Management; Humans; | 2018 |
Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinogens; Cell Proliferation; Cells, Cultured; Female; Gene E | 2018 |
Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.
Topics: Adenoma; Animals; Ataxia Telangiectasia Mutated Proteins; Azoxymethane; Carcinoma; Colonic Neoplasms | 2018 |
6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype.
Topics: Animals; Arginase; Catechols; Enzyme Inhibitors; Fatty Alcohols; Female; Humans; Interleukin-10; Int | 2018 |
A facile approach for fabricating CD44-targeted delivery of hyaluronic acid-functionalized PCL nanoparticles in urethane-induced lung cancer: Bcl-2, MMP-9, caspase-9, and BAX as potential markers.
Topics: A549 Cells; Animals; Antineoplastic Agents; Biomarkers, Tumor; Capsaicin; Carcinoma, Non-Small-Cell | 2019 |
Biotinylated naringenin intensified anticancer effect of gefitinib in urethane-induced lung cancer in rats: favourable modulation of apoptotic regulators and serum metabolomics.
Topics: A549 Cells; Animals; Apoptosis Regulatory Proteins; Drug Screening Assays, Antitumor; Female; Flavan | 2018 |
XPC protects against smoking- and carcinogen-induced lung adenocarcinoma.
Topics: Adenocarcinoma; Animals; Carcinogens; Cigarette Smoking; DNA Damage; Female; Humans; Lung Neoplasms; | 2019 |
Liquid crystalline assembly for potential combinatorial chemo-herbal drug delivery to lung cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cell Proliferation; Drug Deliv | 2019 |
A synergistic approach for management of lung carcinoma through folic acid functionalized co-therapy of capsaicin and gefitinib nanoparticles: Enhanced apoptosis and metalloproteinase-9 down-regulation.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capsaicin; Cell Surv | 2019 |
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.
Topics: Adenocarcinoma of Lung; Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Diethylnitrosamine; | 2019 |
Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis.
Topics: Allografts; Animals; Blood Coagulation Disorders; Carcinogenesis; Carcinoma, Lewis Lung; Emodin; Ext | 2019 |
Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.
Topics: A549 Cells; Animals; Apolipoproteins E; Cell Line, Tumor; Cell Proliferation; Cell Transformation, N | 2019 |
CCAAT/enhancer-binding protein-α suppresses lung tumor development in mice through the p38α MAP kinase pathway.
Topics: Animals; CCAAT-Enhancer-Binding Protein-alpha; Cell Death; Cell Proliferation; Disease Models, Anima | 2013 |
Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model.
Topics: Adenoma; Animals; Antigens, Neoplasm; Cancer Vaccines; Carcinogenesis; Cyclophosphamide; Cytokines; | 2013 |
Multigenic nature of the mouse pulmonary adenoma progression 1 locus.
Topics: Adenoma; Animals; Chromosome Mapping; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p16; Genet | 2013 |
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Topics: Animals; Carcinoma; Cell Proliferation; Disease Progression; Gene Expression Regulation, Enzymologic | 2013 |
[Metformin effect on urethane-induced tumorigenesis in mice].
Topics: Adenoma; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, N | 2012 |
SPECT/CT of lung nodules using 111In-DOTA-c(RGDfK) in a mouse lung carcinogenesis model.
Topics: Animals; Autoradiography; Cell Line, Tumor; Disease Models, Animal; Epithelial Cells; Gene Expressio | 2013 |
Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis.
Topics: Adenocarcinoma; Animals; Base Sequence; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2E1; DN | 2013 |
The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis.
Topics: Animals; Carcinogenesis; Disease Progression; Disease Susceptibility; DNA, Mitochondrial; Electron T | 2013 |
Altered miRNA expression profiles and miR-1a associated with urethane-induced pulmonary carcinogenesis.
Topics: Animals; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mice; Mice, Inbred BALB C; MicroRNA | 2013 |
Myeloid-derived suppressor cells and associated events in urethane-induced lung cancer.
Topics: Actins; Animals; Blotting, Western; Carcinogens; Flow Cytometry; Immunohistochemistry; Interleukin-6 | 2013 |
Effects of selenium on Pteridium aquilinum and urethane-induced lung carcinogenesis.
Topics: Adenoma; Animals; Carcinogens; Dietary Supplements; Female; Indans; Lung Neoplasms; Mice; Pteridium; | 2013 |
Antineoplastic and immunomodulatory effect of polyphenolic components of Achyranthes aspera (PCA) extract on urethane induced lung cancer in vivo.
Topics: Achyranthes; Animals; Antineoplastic Agents, Phytogenic; Catalase; Cytokines; DNA; Drug Screening As | 2014 |
Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.
Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; DNA Pr | 2014 |
Involvement of epigenetics and microRNA-29b in the urethane induced inception and establishment of mouse lung tumors.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; | 2014 |
Involvement of EZH2, SUV39H1, G9a and associated molecules in pathogenesis of urethane induced mouse lung tumors: potential targets for cancer control.
Topics: Animals; Enhancer of Zeste Homolog 2 Protein; Female; Histone-Lysine N-Methyltransferase; Histones; | 2014 |
Differential roles of STAT3 in the initiation and growth of lung cancer.
Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regul | 2015 |
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplasti | 2015 |
Decreased tumorigenesis in mice with a Kras point mutation at C118.
Topics: Alleles; Animals; Carcinogenesis; Carcinogens; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57B | 2014 |
Rare codons capacitate Kras-driven de novo tumorigenesis.
Topics: Adenoma; Animals; Carcinogenesis; Cell Proliferation; Cells, Cultured; Codon; Female; Humans; Lung N | 2015 |
PRDX6 promotes tumor development via the JAK2/STAT3 pathway in a urethane-induced lung tumor model.
Topics: Adenocarcinoma; Animals; Chemokine CCL5; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glut | 2015 |
Assessing the Effects of Concurrent versus Sequential Cisplatin/Radiotherapy on Immune Status in Lung Tumor-Bearing C57BL/6 Mice.
Topics: Adenoma; Animals; Cisplatin; Combined Modality Therapy; Cytokines; Humans; Lung Neoplasms; Mice; Mic | 2015 |
Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression.
Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Carcinogenesis; Disease Model | 2014 |
G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1.
Topics: Adenocarcinoma; Aged; Animals; Apoptosis; Blotting, Western; Carcinogens; Carcinoma, Non-Small-Cell | 2015 |
A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response.
Topics: Acetone; Animals; Anticarcinogenic Agents; Arsenites; Benzyl Compounds; Carcinogenesis; Cell Line, T | 2015 |
Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis.
Topics: Animals; Antioxidants; Carcinogenesis; Carcinogens; Comet Assay; DNA Damage; Ericales; Genome; Immun | 2015 |
NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.
Topics: Animals; Carcinogenesis; Cell Line, Tumor; Enzyme Stability; Gene Knockout Techniques; Genes, ras; H | 2016 |
Induction of Lung Tumors in Mice with Urethane.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Carcinogens; Injections, Intraperitoneal; Lun | 2015 |
Sex-Related Differences in the Sensitivity to Carcinogenic Effect of Urethane on the Lungs in Mice Are Reversed after Neonatal Androgenization.
Topics: Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug; Dru | 2015 |
Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Diseas | 2016 |
Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide.
Topics: Acrylamides; Adenocarcinoma; Adenoma; Animals; Aurora Kinase B; Biomarkers, Tumor; Carcinoembryonic | 2015 |
The Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound Healing.
Topics: Animals; Apoptosis; Biological Products; Body Weight; Carcinogenesis; Cell Differentiation; Cell Lin | 2015 |
The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Autophagy; Benzofurans; Capillary Permea | 2016 |
AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.
Topics: Animals; Bronchi; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Fe | 2016 |
Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model.
Topics: Administration, Intranasal; Animals; Apoptosis; Carcinogenesis; Collagen Type V; DNA Fragmentation; | 2016 |
NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth.
Topics: Animals; Cell Transformation, Neoplastic; Gene Expression Profiling; Lung Neoplasms; Male; Mice; Mic | 2016 |
Prostacyclin reverses the cigarette smoke-induced decrease in pulmonary Frizzled 9 expression through miR-31.
Topics: Animals; Bronchi; Cells, Cultured; Epithelial Cells; Epoprostenol; Frizzled Receptors; Gene Expressi | 2016 |
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Topics: Animals; Capsaicin; Carcinogenesis; Catechols; Disease Models, Animal; ErbB Receptors; Fatty Alcohol | 2016 |
Inflammation has a role in urethane‑induced lung cancer in C57BL/6J mice.
Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Carcinogens; Disease Models, Animal; Humans; Inf | 2016 |
Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Topics: Alleles; Animals; Cell Transformation, Neoplastic; Isoenzymes; Lung Neoplasms; Mice; Mice, Knockout; | 2016 |
Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.
Topics: Animals; Cell Transformation, Neoplastic; Lung Neoplasms; Mice; Mice, Knockout; Neoplasms, Experimen | 2017 |
Antitumor activity of intratracheal inhalation of temozolomide (TMZ) loaded into gold nanoparticles and/or liposomes against urethane-induced lung cancer in BALB/c mice.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Dacarbazi | 2017 |
Periodic analysis of urethane-induced pulmonary tumors in living A/J mice by respiration-gated X-ray microcomputed tomography.
Topics: Animals; Carcinogens; Disease Models, Animal; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Resp | 2008 |
Overexpression of Sprouty 2 in mouse lung epithelium inhibits urethane-induced tumorigenesis.
Topics: Adaptor Proteins, Signal Transducing; Alkaline Phosphatase; Animals; Carcinogens; Female; GPI-Linked | 2009 |
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
Topics: Animals; Carcinogens; Disease Models, Animal; Exons; Genes, ras; Humans; Lung; Lung Neoplasms; Mice; | 2008 |
Pulmonary-tumor induction with alkylated urethans.
Topics: Humans; Lung; Lung Neoplasms; Neoplasms; Urethane | 1948 |
The neoplastic potentialities of mouse embryo tissues; lung adenomas in baby mice as result of prenatal exposure to urethane.
Topics: Adenoma; Animals; Cell Division; Epithelial Cells; Female; Lung; Lung Neoplasms; Mice; Neoplasms; Ne | 1948 |
Some studies on the action of urethane on mice.
Topics: Animals; Lung; Lung Neoplasms; Mice; Neoplasms; Urethane | 1947 |
Tumor of the lung in rats following injections of urethane (ethylcarbamate).
Topics: Animals; Injections; Lung; Lung Neoplasms; Neoplasms; Rats; Urethane | 1947 |
Inhibition of vinyl carbamate-induced lung tumors and Kras2 mutations by the garlic derivative diallyl sulfone.
Topics: Allyl Compounds; Amino Acid Substitution; Animals; Garlic; Lung Neoplasms; Mice; Mutation; Proto-Onc | 2009 |
Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci.
Topics: Animals; Carcinogens; Chromosome Mapping; Disease Models, Animal; Female; Gene Expression Regulation | 2009 |
FTY720 and lung tumor development.
Topics: Adenoma; Animals; Fingolimod Hydrochloride; Immunosuppressive Agents; Lung Neoplasms; Male; Mice; Mi | 2009 |
Lung tumor development in the presence of sphingosine 1-phosphate agonist FTY720.
Topics: Adenoma; Animals; Apoptosis; Caspase 3; Cell Proliferation; Disease Models, Animal; Dose-Response Re | 2009 |
Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice.
Topics: Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Line, Tumor; Growth Differentiation Factor | 2009 |
Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Prol | 2010 |
Comparison of Ki-67 antigen expression and K-ras mutation in lung tumours induced by urethane in mice.
Topics: Animals; Cholecalciferol; Exons; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Ki-67 A | 2009 |
Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Nucleus; Chromones; Cyclin-Dependent Kinase Inhibitor | 2009 |
FoxO3a gene is a target of deletion in mouse lung adenocarcinoma.
Topics: Adenocarcinoma; Aflatoxin B1; Animals; Carcinogens; Disease Models, Animal; Forkhead Box Protein O3; | 2009 |
Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Blotting, Western; Female; Gene Expression Profili | 2010 |
Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.
Topics: Adenocarcinoma; Animals; Cell Proliferation; Fatty Acids, Unsaturated; Female; Ligands; Lung Neoplas | 2009 |
Transcriptome of normal lung distinguishes mouse lines with different susceptibility to inflammation and to lung tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Gene Expression; Gene Expr | 2010 |
Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer.
Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Proliferation; Core Binding Factor Alpha 3 Subun | 2010 |
In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Genetic Therapy; Inflammation; Lung Neoplasms; M | 2010 |
Association between decreases in type V collagen and apoptosis in mouse lung chemical carcinogenesis: a preliminary model to study cancer cell behavior.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Carcinogens; Caspase 9; Collagen Type V; Disease Models, Anim | 2010 |
Vascular endothelial growth factor receptor 2-targeted chemoprevention of murine lung tumors.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carc | 2010 |
Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Carcinogenicity Tests; Disease Models, Animal; Lung; Lung Neo | 2010 |
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Chemopreventi | 2010 |
Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.
Topics: Animals; Anticarcinogenic Agents; Cell Proliferation; Down-Regulation; Gene Deletion; Intermediate F | 2011 |
Endothelial cell-specific deletion of transcription factor FoxM1 increases urethane-induced lung carcinogenesis.
Topics: Animals; Cell Proliferation; Chromatin Immunoprecipitation; Endothelium, Vascular; Forkhead Box Prot | 2011 |
Identification of myeloid-derived suppressor cells and T regulatory cells in lung microenvironment after Urethane-induced lung tumor.
Topics: Adaptive Immunity; Animals; Antigens, Ly; Carcinogens; CD11b Antigen; CD4 Antigens; Forkhead Transcr | 2011 |
Protein kinase C δ is a downstream effector of oncogenic K-ras in lung tumors.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferat | 2011 |
Urban, traffic- related particles and lung tumors in urethane treated mice.
Topics: Air Pollutants; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Envir | 2011 |
Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes.
Topics: Animals; Cell Proliferation; Cell Survival; Chronic Disease; Epithelium; Humans; Inflammation; Lung; | 2012 |
Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation.
Topics: Animals; Bronchi; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Profiling; Ge | 2011 |
Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice.
Topics: Animals; Carcinogens; Female; Gene Deletion; Gene Expression Profiling; Lung Neoplasms; Mice; Mice, | 2011 |
A critical role for macrophages in promotion of urethane-induced lung carcinogenesis.
Topics: Animals; Carcinogens; Cell Separation; Cell Transformation, Neoplastic; Female; Flow Cytometry; Immu | 2011 |
Characterization of a murine lung adenocarcinoma (LAC1), a useful experimental model to study progression of lung cancer.
Topics: Adenocarcinoma; Animals; Cell Proliferation; Cells, Cultured; Concanavalin A; Erythrocyte Count; Hem | 2011 |
Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.
Topics: Animals; Atorvastatin; Colonic Neoplasms; Dimethylhydrazines; Female; Heptanoic Acids; Histone Deace | 2012 |
Neutralization of tumor necrosis factor bioactivity ameliorates urethane-induced pulmonary oncogenesis in mice.
Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Etanerc | 2011 |
Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Betacyanins; Caspases; Cell Transformat | 2013 |
Inhibitory roles of signal transducer and activator of transcription 3 in antitumor immunity during carcinogen-induced lung tumorigenesis.
Topics: Animals; Apoptosis; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferatio | 2012 |
The influence of physical activity in the progression of experimental lung cancer in mice.
Topics: Animals; Carcinogens; Disease Models, Animal; Disease Progression; Hyperplasia; Lung Neoplasms; Male | 2012 |
Alveolar hypoxia promotes murine lung tumor growth through a VEGFR-2/EGFR-dependent mechanism.
Topics: Animals; Antioxidants; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Blotting, We | 2012 |
Strain-specific variation in murine natural killer gene complex contributes to differences in immunosurveillance for urethane-induced lung cancer.
Topics: Adaptive Immunity; Animals; Bone Marrow Cells; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Lin | 2012 |
Involvement of STAT3, NF-κB and associated downstream molecules before and after the onset of urethane induced lung tumors in mouse.
Topics: Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Female; Interleukin-6; Lung Neoplasms; Mice; Mice | 2012 |
PET imaging of tumor associated macrophages using mannose coated 64Cu liposomes.
Topics: Animals; Copper Radioisotopes; Female; Liposomes; Lung Neoplasms; Macrophages; Magnetic Resonance Im | 2012 |
Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-κB and inhibition of monocyte chemoattractant protein-1 in urethane-induced lung tumor model.
Topics: Animals; Apoptosis; CCR5 Receptor Antagonists; CD8-Positive T-Lymphocytes; Chemokine CCL2; Dendritic | 2012 |
Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Epistasis, Genetic; Fema | 2013 |
The influence of physical activity in the progression of experimental lung cancer in mice.
Topics: Adaptation, Physiological; Animals; Carcinogens; Disease Progression; Lung; Lung Neoplasms; Mice; Ne | 2012 |
Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy.
Topics: Animals; Apoptosis; Autophagy; Cell Division; Cell Line, Tumor; Chemoprevention; Down-Regulation; Er | 2012 |
Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
Topics: Adenocarcinoma, Mucinous; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; Cell Line, | 2012 |
Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinogens; Humans; Hyperplasia; Immunohis | 2012 |
[Effect of aconiti lateralis radix praeparata and taraxaci herba on Chinese medicine signs and symptoms of urethane-induced lung cancer in mice].
Topics: Aconitum; Animals; Blood Circulation; Drugs, Chinese Herbal; Female; Humans; Lung Neoplasms; Mice; M | 2012 |
Prevention of mouse lung tumors by budesonide and its modulation of biomarkers.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Budesonide; Cell Divis | 2002 |
Altered expression of G1/S regulatory genes occurs early and frequently in lung carcinogenesis in transforming growth factor-beta1 heterozygous mice.
Topics: Adenocarcinoma; Animals; Cell Cycle Proteins; Cell Division; DNA Primers; Female; G1 Phase; Gene Exp | 2002 |
Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dose-Response Relationship, Drug; Female; Hydroxyurea | 2002 |
Effect of myelopeptide-2 on the development of spontaneous and urethane-induced tumors in mice.
Topics: Adenoma; Animals; Antineoplastic Agents; Carcinogens; Lung Neoplasms; Male; Mice; Oligopeptides; Ure | 2002 |
Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis.
Topics: Adenocarcinoma; Animals; Carcinogens; Loss of Heterozygosity; Lung Neoplasms; Mice; Mice, Inbred A; | 2002 |
Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Endothelial Growth Factors; Immunohistochemistry; In | 2002 |
Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2.
Topics: Adenoma; Alleles; Alternative Splicing; Amino Acid Substitution; Animals; Animals, Congenic; Chimera | 2003 |
Investigation of ethyl alcohol and beta-carotene effect on two models of carcinogenesis.
Topics: Animals; Benzo(a)pyrene; beta Carotene; Carcinogens; Ethanol; Liver; Lung Neoplasms; Mice; Mice, Inb | 2003 |
Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice.
Topics: Animals; Carcinogens; Codon; Crosses, Genetic; Female; Genes, ras; Lung Neoplasms; Male; Mice; Mice, | 2003 |
Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines.
Topics: Adenoma; Animals; Chromosome Mapping; Crosses, Genetic; Gene Expression Profiling; Genes, ras; Genet | 2003 |
Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections.
Topics: Adenocarcinoma; Animals; Butylated Hydroxytoluene; Carcinogens; Disease Models, Animal; Incidence; L | 2003 |
[Experimental lung adenomas induced by urethane].
Topics: Adenoma; Animals; Carcinogens; Lung Neoplasms; Neoplasms, Experimental; Urethane | 1952 |
[On urethane-induced experimental adenomas of the lung].
Topics: Adenoma; Animals; Lung; Lung Neoplasms; Neoplasms, Experimental; Urethane | 1953 |
Pulmonary-tumor induction in mice with chemical agents used in the clinical management of lymphomas.
Topics: Animals; Carcinogens; Lung Neoplasms; Lymphoma; Mechlorethamine; Mice; Neoplasms, Experimental; Nitr | 1954 |
Induction of lung adenomas following exposure of pregnant, newborn, and immature male mice to urethan.
Topics: Adenoma; Animals; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Pregnancy; Urethane | 1954 |
[Attempted cocarcinogenesis by combined urethane and turpentine in mice].
Topics: Animals; Cocarcinogenesis; Lung Neoplasms; Mice; Neoplasms, Experimental; Turpentine; Urethane | 1953 |
Pulmonary tumours in urethane-treated mice: failure to demonstrate an underlying infective aetiology.
Topics: Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1955 |
Some quantitative observations on the induction and growth of primary pulmonary tumors in strain A mice receiving urethan.
Topics: Animals; Lung; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Urethane | 1955 |
Are carcinogens responsible for the superimposed neoplastic changes occurring in mouse tumor cells? The effect of methylcholanthrene and urethane on pulmonary adenomas and of methylcholanthrene on mammary carcinomas.
Topics: Adenoma; Animals; Breast Neoplasms; Carcinogens; Humans; Lung; Lung Neoplasms; Methylcholanthrene; M | 1955 |
[Effect of adaptation hormones on urethane-induced lung tumors in adrenalectomized mice].
Topics: Adrenal Cortex Hormones; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1956 |
[Effect of adaptation hormones on urethane-induced lung tumors in adrenalectomized mice].
Topics: Adrenal Cortex Hormones; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1956 |
[Effect of adaptation hormones on urethane-induced lung tumors in adrenalectomized mice].
Topics: Adrenal Cortex Hormones; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1956 |
[Effect of adaptation hormones on urethane-induced lung tumors in adrenalectomized mice].
Topics: Adrenal Cortex Hormones; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1956 |
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis.
Topics: Adenine; Adenoma; Animals; DNA; Lung Neoplasms; Mice; Neoplasms; Nucleic Acids; Orotic Acid; Pyrimid | 1957 |
[Morphology and histogenesis of lung adenomas appearing in mice after introduction of urethane].
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1957 |
[Experimental data on blastomogenic activity of urethane].
Topics: Animals; Lung Neoplasms; Neoplasms, Experimental; Urethane | 1955 |
The transplantability and growth of urethan-induced pulmonary adenomas of the mouse.
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1957 |
[Effect of adaptation hormones on urethane lung tumors of an intact mouse].
Topics: Animals; Growth Hormone; Human Growth Hormone; Hydrocortisone; Lung Neoplasms; Mice; Neoplasms, Expe | 1958 |
[Effect of various agents on induced lung tumors].
Topics: Animals; Lung Neoplasms; Neoplasms, Experimental; Urethane | 1957 |
[The effect of ionizing radiations on urethane-induced adenoma of the lungs in mice].
Topics: Adenoma; Animals; Lung; Lung Neoplasms; Mice; Neoplasms, Experimental; Radiation Effects; Radiation, | 1961 |
Skin initiating action and lung carcinogenesis byderivatives of urethane (ethyl carbamate) and related compounds.
Topics: Animals; Carcinogenesis; Carcinogens; Humans; Lung; Lung Neoplasms; Neoplasms, Experimental; Skin Ne | 1959 |
Failure of the urethane antagonist-lysergic acid-diethylamide (LSD-25)--to inhibit lung carcinogenesis or the initiating phase of skin carcinogenesis in mice.
Topics: Animals; Carcinogenesis; Lung Neoplasms; Lysergic Acid Diethylamide; Mice; Neoplasms, Experimental; | 1959 |
Influence of altered atmospheric oxygen on urethan-induced pulmonary tumors in mice.
Topics: Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Oxygen; Urethane | 1959 |
[Morphological studies on experimental murine lung tumor induced by abdominal injection of urethane. 1. Macroscopic and statistical study].
Topics: Abdomen; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1961 |
[Morphological studies on experimental murine lung tumor induced by abdominal injuction of urethane. 3. Electron microscopical study].
Topics: Abdomen; Animals; Electrons; Lung Neoplasms; Mice; Microscopy, Electron; Neoplasms, Experimental; Ur | 1961 |
[The urethane-induced experimental pulmonary adenoma in the mouse. I. Histological study].
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1962 |
Induction of squamous carcinoma of the lung and of the stomach and oesophagus by diazomethane and N-methyl-N-nitroso-urethane, respectively.
Topics: Animals; Azo Compounds; Carcinogens; Carcinoma, Squamous Cell; Diazomethane; Esophageal Neoplasms; L | 1962 |
Inhibition of urethan lung tumor induction in mice by total-body x irradiation.
Topics: Animals; Cell Communication; Lung Neoplasms; Mice; Neoplasms; Radiation Effects; Urethane | 1963 |
Effect of urethane of pulmonary tumors produced by methylcholanthrene.
Topics: Humans; Lung Neoplasms; Methylcholanthrene; Urethane | 1963 |
[On the morphology of lung tumors in rats induced by intravenous injection of nitrosomethyl-urethane].
Topics: Animals; Injections, Intravenous; Lung Neoplasms; Nitroso Compounds; Rats; Urethane | 1963 |
Neoplastic response of various tissues to the administration of urethan.
Topics: Carcinogens; Leukemia; Leukemia, Experimental; Lung Neoplasms; Urethane | 1962 |
Lung carcinogenesis by urethane in newborn, suckling, and adult Swiss mice.
Topics: Animals; Animals, Newborn; Carcinogenesis; Lung Neoplasms; Mice; Urethane | 1962 |
The combined carcinogenic effect of cigarette smoke condensate and urethan.
Topics: Carcinogens; Humans; Lung Neoplasms; Nicotiana; Smoke; Smoking; Tars; Urethane | 1962 |
Induction of lymphocyticlasms, hepatomas, and other tumors after oral administration of urethan to infant mice.
Topics: Administration, Oral; Animals; Carcinoma, Hepatocellular; Leukemia; Leukemia, Lymphoid; Liver Neopla | 1962 |
EXPERIMENTAL INDUCTION OF SQUAMOUS CARCINOMA OF THE LUNG, OESOPHAGUS AND STOMACH. THE MODE OF THEIR INDUCTION.
Topics: Animals; Benzopyrenes; Carcinoma; Carcinoma, Squamous Cell; Esophageal Neoplasms; Lung Neoplasms; Mi | 1963 |
INFLUENCE OF AGE AND ROUTE OF ADMINISTRATION ON LUNG CARCINOGENESIS BY URETHAN IN SWISS MICE.
Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Female; Humans; Lactation; Lung Neoplasms; Mice; | 1963 |
SELECTION FOR INCREASED SUSCEPTIBILITY TO INDUCED LUNG TUMOURS IN THE MOUSE.
Topics: Animals; Disease Susceptibility; Genetics; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; | 1963 |
FURTHER EXPERIENCE WITH COMBINED CYTOTOXIC THERAPY IN BRONCHIAL CARCINOMA.
Topics: Bronchial Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide; Geriatrics; Leukopenia; Lung Neoplas | 1963 |
INHIBITION OF URETHAN LUNG TUMOR INDUCTION IN MICE BY TOTAL-BODY X-RADIATION.
Topics: Carcinogens; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Radiation Effects; Research; | 1963 |
X-RAY INHIBITION OF URETHAN-STIMULATED PROLIFERATION OF LUNG CELLS OF THE MOUSE AS ESTIMATED BY INCORPORATION OF TRITIATED THYMIDINE.
Topics: Animals; Carcinogens; Lung Neoplasms; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Radiatio | 1963 |
[MALIGNANT DEGENERATION OF THE URETHANE-INDUCED EXPERIMENTAL PULMONARY ADENOMA OF THE SWISS MOUSE. I. HISTOLOGICAL STUDY].
Topics: Adenoma; Lung Diseases; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Research; Toxicolo | 1963 |
[ON THE DEVELOPMENT OF SUBMICROSCOPIC CELLULAR INCLUSIONS IN LUNG TUMORS IN MICE].
Topics: Cell Nucleus; Electrons; Inclusion Bodies; Lung Neoplasms; Mice; Microscopy; Microscopy, Electron; R | 1963 |
INHIBITION BY URETHAN (ETHYL CARBAMATE) OF VIRUS INDUCTION OF LEUKAEMIA IN C3H MICE.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Leukemia; Leukemia, Experimental; Liver Neoplasms; Lung | 1963 |
[A MORPHOLOGICAL STUDY ON EXPERIMENTAL LUNG NEOPLASMS INDUCED BY URETHANE IN THE MOUSE ABDOMEN. 4. CHANGES IN THE MOUSE LUNG BY INJECTIONS OF URETHANE INTO THE PLACENTA].
Topics: Abdomen; Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Female; Fetus; Humans; Lung Neoplasm | 1963 |
INFLUENCE OF MUTAGENS ON THE INITIATION OF SKIN CARCINOGENESIS.
Topics: 2-Aminopurine; Acridines; Adenine; Carcinogenesis; Carcinogens; Idoxuridine; Lung Neoplasms; Mice; M | 1964 |
THE TISSUE REACTION TO HYPERBARIC OXYGEN.
Topics: Adenoma; Epididymis; Humans; Hyperbaric Oxygenation; Kidney; Lung; Lung Neoplasms; Male; Metabolism; | 1964 |
[CYTOSTATIC THERAPY].
Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambucil; Colchicine; Cyclophosphamide; Femal | 1964 |
TRENDS IN CARCINOGENESIS BY URETHAN ADMINISTRATION TO NEW-BORN MICE OF DIFFERENT STRAINS.
Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Genetics | 1964 |
[MALIGNANT DEGENERATION OF THE URETHANE-INDUCED EXPERIMENTAL PULMONARY ADENOMA IN THE SWISS MOUSE. 2. CYTOLOGICAL STUDY BY ELECTRON MICROSCOPE].
Topics: Adenoma; Electrons; Lung Neoplasms; Mice; Microscopy; Microscopy, Electron; Neoplasms; Neoplasms, Ex | 1964 |
CHANGES IN SUSCEPTIBILITY TO URETHANE-INDUCED LUNG TUMOURS PRODUCED BY SELECTIVE BREEDING IN MICE.
Topics: Breeding; Genetics; Injections, Intraperitoneal; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experim | 1964 |
THE CARCINOGENIC AND CO-CARCINOGENIC EFFECTS OF PARAFFIN WAX PELLETS AND GLASS BEADS IN THE MOUSE BLADDER.
Topics: Animals; Carcinogens; Epithelium; Foreign Bodies; Glass; Hyperplasia; Leukemia; Leukemia, Myeloid; L | 1964 |
[STRUCTURE AND PATHOLOGY OF THE ALVEOLI OF THE LUNG (LIGHT AND ELECTRON MICROSCOPE STUDIES)].
Topics: Anatomy; Animals; Electrons; Exudates and Transudates; Fetus; Lung; Lung Neoplasms; Mice; Microscopy | 1963 |
[HISTOCHEMICAL STUDIES ON PULMONARY ADENOMAS INDUCED IN MICE WITH URETHANE].
Topics: Adenoma; Animals; DNA; DNA, Neoplasm; Electron Transport Complex IV; Histocytochemistry; Lung Neopla | 1964 |
HORMONAL INFLUENCES ON URETHAN CARCINOGENESIS IN C3H/F MICE.
Topics: Adrenal Gland Neoplasms; Androgens; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinom | 1964 |
INTERACTION OF URETHAN AND FRACTIONATED OR REGIONAL X-RADIATION IN MICE: LUNG TUMOR AND LEUKEMIA INCIDENCE.
Topics: Animals; Incidence; Leukemia; Leukemia, Experimental; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Ex | 1964 |
URACIL MUSTARD: A POTENT INDUCER OF LUNG TUMORS IN MICE.
Topics: DNA; Lung Neoplasms; Mechlorethamine; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Com | 1965 |
[RELATIONSHIP BETWEEN CANCER AND TUBERCULOSIS. 2). A RETARDING EFFECT OF BCG INOCULATION FOR TUMOR INDUCTION IN MICE WITH INH OR URETHANE-4 NQO INJECTIONS].
Topics: Animals; Antitubercular Agents; BCG Vaccine; Isoniazid; Lung Neoplasms; Mice; Mycobacterium bovis; N | 1964 |
CHROMOSOME PATTERNS IN MOUSE LUNG TUMORS.
Topics: Adenoma; Animals; Chromosomes; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms; Neoplasms, | 1965 |
Studies of the mechanism of action of urethan in initiating pulmonary adenomas in mice. I. The indirect nature of its oncogenic influence.
Topics: Adenoma; Animals; Carcinogens; Lung Neoplasms; Mice; Urethane | 1955 |
[Experimental induction of lung tumors by urethane-ultrasonics-aerosols].
Topics: Aerosols; Humans; Lung Neoplasms; Ultrasonics; Urethane | 1961 |
[Experimental studies on pulmonary tumors produced with urethane in mice].
Topics: Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Urethane | 1961 |
[Provocation of lung tumors in the white mouse by urethane-ultrasonics aerosols].
Topics: Aerosols; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Ultrasonics; Urethane | 1962 |
Serum levels of surfactant protein D are increased in mice with lung tumors.
Topics: Adenocarcinoma; Animals; Carcinogens; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, | 2003 |
[Immunotherapy of lung tumors in Balb/c mice].
Topics: Animals; Carcinogens; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Prot | 2003 |
Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency.
Topics: Alleles; Animals; Body Weight; Disease Susceptibility; Female; Gene Deletion; Heterozygote; Homozygo | 2003 |
Prevalence of liver tumours in HIV-1 tat-transgenic mice treated with urethane.
Topics: Animals; Carcinogens; Cell Division; DNA, Complementary; Female; Gene Products, tat; HIV Infections; | 2004 |
Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression.
Topics: Adenocarcinoma; Animals; Carcinogens; Chromosomal Instability; Chromosome Deletion; Chromosome Mappi | 2004 |
Age of the host and other factors affecting the production with urethane of pulmonary adenomas in mice.
Topics: Adenoma; Animals; Cell Nucleus; Lung; Lung Neoplasms; Mice; Urethane | 1951 |
The histopathogenesis of pulmonary tumors induced in strain A mice by urethan.
Topics: Animals; Lung; Lung Neoplasms; Mice; Neoplasms; Urethane | 1951 |
Histogeny of pulmonary tumours induced in the mouse by urethane (ethyl carbamate).
Topics: Animals; Lung Neoplasms; Mice; Urethane | 1951 |
The transplacental effect of urethan on lung tumor genesis in mice.
Topics: Animals; Lung Neoplasms; Mice; Urethane | 1952 |
Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice.
Topics: Adenoma; Alleles; Amino Acid Substitution; Animals; Chromosome Mapping; Crosses, Genetic; Female; Ge | 2004 |
Serum levels of surfactant protein D are increased in mice with lung tumors.
Topics: Animals; Biomarkers, Tumor; Carcinogens; Enzyme-Linked Immunosorbent Assay; Lung Neoplasms; Mice; Mi | 2004 |
Sprouty 2 gene in mouse lung tumorigenesis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinogens; Carcinoma, Non-Small-Cell Lung; Humans; | 2004 |
Increased susceptibility to urethane-induced lung tumors in mice with decreased expression of connexin43.
Topics: Adenoma; Animals; Carcinogens; Connexin 43; Disease Susceptibility; Gene Deletion; Heterozygote; Lun | 2004 |
Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens.
Topics: Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; C | 2004 |
Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy.
Topics: Adenoma; Animals; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Lung | 2004 |
Chemoprevention: mouse colon and lung tumor bioassay and modulation of DNA methylation as a biomarker.
Topics: Animals; Azoxymethane; Biological Assay; Biomarkers; Budesonide; Carcinogens; Chemoprevention; Colon | 2005 |
Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains.
Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Disease Models, Animal; Genes, p53; Genes, ras; Genet | 2005 |
A moderate reduction of Bcl-x(L) expression protects against tumorigenesis; however, it also increases susceptibility to tissue injury.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Central Nervous System Depressants; Ethano | 2005 |
Increased susceptibility of vault poly(ADP-ribose) polymerase-deficient mice to carcinogen-induced tumorigenesis.
Topics: Animals; Carcinogens; Carrier Proteins; Colonic Neoplasms; Dimethylhydrazines; Female; Lung Neoplasm | 2005 |
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Progression; Genes, ras; | 2006 |
Prevention of lung cancer progression by bexarotene in mouse models.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Carcinoma, Non-S | 2006 |
Gene expression analysis of urethane-induced lung tumors in ras H2 mice.
Topics: Adenoma; Animals; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation, Neoplasti | 2006 |
Prevention of mouse lung tumors by targretin.
Topics: Animals; Anticarcinogenic Agents; Bexarotene; Chemoprevention; Dose-Response Relationship, Drug; Fem | 2006 |
Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Disease Susceptibility; | 2006 |
Immobilization effect of air-injected blanket (AIB) for abdomen fixation.
Topics: Abdomen; Abdominal Cavity; Abdominal Neoplasms; Air; Bedding and Linens; Breast Neoplasms; Fluorosco | 2005 |
A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dep | 2006 |
The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer.
Topics: Adenocarcinoma; Alleles; Animals; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Growth Process | 2006 |
Effect of silibinin on the growth and progression of primary lung tumors in mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cell P | 2006 |
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
Topics: Adenoma; Alleles; Animals; Carcinogens; Female; Genetic Predisposition to Disease; Lung Neoplasms; M | 2006 |
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT).
Topics: Animals; Anti-Inflammatory Agents; Budesonide; Chemoprevention; Disease Models, Animal; DNA Methylat | 2007 |
Altered expression of connexins in urethane-induced mouse lung adenomas.
Topics: Adenoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Connexins; Gene Expression Regulatio | 2006 |
Inhibition of urethane-induced carcinogenicity in cyp2e1-/- in comparison to cyp2e1+/+ mice.
Topics: Animals; Cytochrome P-450 CYP2E1; Eye Neoplasms; Harderian Gland; Inactivation, Metabolic; Liver Neo | 2007 |
Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers, Tumor; Body Weight; Budesonide; Caspase 3; Cell Proli | 2007 |
[Sensibility of several mouse strains to urethane induced lung tumors].
Topics: Animals; Carcinogens; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, I | 2006 |
[Melatonin inhibits urethane-induced carcinogenesis tumors in murine lung].
Topics: Adenoma; Animals; Antineoplastic Agents; Antioxidants; Biomarkers, Tumor; Catalase; Lung Neoplasms; | 2006 |
Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice.
Topics: Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Bone Marrow; Carcinogens; Cell Transformation, | 2007 |
Modulation by budesonide of a CpG endonuclease in mouse lung tumors.
Topics: Animals; Anti-Inflammatory Agents; Budesonide; CpG Islands; DNA Methylation; Endonucleases; Enzyme A | 2007 |
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Lung; Lung Ne | 2007 |
Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia.
Topics: Animals; Biomarkers, Tumor; Butylated Hydroxytoluene; Carcinogens; Cell Line; Cell Proliferation; Ce | 2007 |
Modulation by bexarotene of mRNA expression of genes in mouse lung tumors.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Bexarotene; DNA Methyltransferase 3A; Drug A | 2008 |
Glutathione transferase pi plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenoma; Animals; Benzo(a)pyrene; Carcinogens; D | 2007 |
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.
Topics: Adenocarcinoma; Animals; Bronchi; Cell Transformation, Neoplastic; Gene Expression; Lung; Lung Neopl | 2007 |
Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis.
Topics: Animals; Cell Transformation, Neoplastic; Disease Susceptibility; Epithelial Cells; Female; Lung Neo | 2007 |
[Atypical effect of urethane in leukemia].
Topics: Bronchi; Carcinoma, Bronchogenic; Humans; Leukemia; Lung Neoplasms; Pneumonectomy; Urethane | 1948 |
Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors.
Topics: Animals; Base Sequence; Carcinogens; Exons; Female; Genes, erbB-1; Genes, ras; Lung Neoplasms; Mice; | 2008 |
Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis.
Topics: Administration, Inhalation; Aerosols; Animals; Carcinogens; Cell Cycle Proteins; Drug Carriers; Gene | 2008 |
Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging.
Topics: Adenocarcinoma; Animals; Carcinogens; Disease Models, Animal; Image Interpretation, Computer-Assiste | 2008 |
Effects of vitamin D in lung, stomach, esophagus and testis tissues following administration of urethane in balb/c mice.
Topics: Animals; Esophagus; Female; Genes, ras; Humans; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred BALB | 2008 |
Inhibiting fatty acid synthase for chemoprevention of chemically induced lung tumors.
Topics: Animals; Anticarcinogenic Agents; Enzyme Inhibitors; Fatty Acid Synthases; Female; Humans; Lung Neop | 2008 |
FTY720 treatment in experimentally urethane-induced lung tumors.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Anticarcinogenic Agents; Carcinogens; Disease Models, | 2008 |
[Comparison of gamma-phenylpropylcarbamate and urethane in a carcinogen test in mice].
Topics: Adenoma; Animals; Animals, Newborn; Carcinogens; Female; Injections, Subcutaneous; Leukemia, Lymphoi | 1966 |
Fibrosing alveolitis and atypical proliferative lesions of the lung. An experimental study in Syrian hamsters.
Topics: Animals; Carcinogens; Cricetinae; Lung Neoplasms; Neoplasms, Experimental; Nitroso Compounds; Pulmon | 1967 |
Neoplasms in the rat associated with administration of urethan and aflatoxin.
Topics: Adenoma; Aflatoxins; Animals; Choline Deficiency; Diet; Hemangioendothelioma; Liver Cirrhosis; Liver | 1967 |
Multiple myeloma with cutaneous involvement.
Topics: Adult; Aged; Antitubercular Agents; Cyclophosphamide; Humans; Lung Neoplasms; Male; Melphalan; Multi | 1967 |
The comparison of teratogenic and carcinogenic effects of some carbamate compounds.
Topics: Abnormalities, Drug-Induced; Animals; Carbamates; Carcinogens; Cricetinae; Female; Injections, Intra | 1967 |
Enhancement of lung adenoma formation by neonatal thymectomy in mice treated with 7,12-dimethylbenz(a)anthracene or urethan.
Topics: Adenoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Carcinogens; Lung Neoplasms; Mice; Neoplasms | 1967 |
Enhancement of N-bis(2-hydroxypropyl)nitrosamine-initiated lung tumor development in rats by bleomycin and N-methyl-N-nitrosourethane.
Topics: Adenocarcinoma; Animals; Bleomycin; Carcinogens; Drug Synergism; Hyperplasia; Lung; Lung Neoplasms; | 1984 |
EPA studies on the toxicological effects of inhaled diesel engine emissions.
Topics: Air Pollutants; Animals; Atmosphere Exposure Chambers; Behavior, Animal; Carcinogens, Environmental; | 1982 |
Alterations in cyclic adenosine 3':5'-monophosphate-dependent protein kinases during normal and neoplastic lung development.
Topics: Adenoma; Animals; Animals, Newborn; Autoradiography; Cyclic AMP; Lung; Lung Neoplasms; Male; Mice; N | 1981 |
Short- and long-term studies on chemical carcinogenesis in BALB/Mo mice.
Topics: Adenoma; Animals; Animals, Newborn; Bromodeoxyuridine; Cocarcinogenesis; Deoxyadenosines; Female; Lu | 1984 |
Anticarcinogenic effect of long-term oral administration of red ginseng on newborn mice exposed to various chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Animals, Newborn; Carc | 1983 |
Inhibition of 7,12-dimethylbenz[a]anthracene- and urethan-induced lung tumor formation in A/J mice by long-term treatment with dehydroepiandrosterone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Dehydroepiandrosterone; | 1981 |
Enhancement of urethan-induced adenoma formation in Swiss mice exposed to methylmercury.
Topics: Adenoma; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Immune Tolerance; Lung N | 1984 |
The role of toxicological interactions in chemical carcinogenesis.
Topics: Administration, Oral; Animals; Anisoles; Benzo(a)pyrene; Butylated Hydroxyanisole; Butylated Hydroxy | 1984 |
[Effect of selenium on transplacental carcinogenesis].
Topics: Animals; Drug Antagonism; Ethylnitrosourea; Female; Lung Neoplasms; Male; Mice; Neoplasms, Experimen | 1984 |
Consideration of the mechanism of pulmonary adenogenesis in urethane-treated Swiss mice.
Topics: Adenoma; Animals; DDT; Dose-Response Relationship, Drug; Kinetics; Lung Neoplasms; Male; Mice; Ureth | 1984 |
Butylated hydroxyanisole and lung tumor development in A/J mice.
Topics: Animals; Anisoles; Benzo(a)pyrene; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Division | 1984 |
Spontaneous and urethan-induced tumor incidence in B6C3F1 versus B6CF1 mice.
Topics: Animals; Disease Models, Animal; Female; Hybridization, Genetic; Liver Neoplasms, Experimental; Lung | 1984 |
Major effect on susceptibility to urethan-induced pulmonary adenoma by a single gene in BALB/cBy mice.
Topics: Adenoma; Animals; Crosses, Genetic; Disease Susceptibility; Female; Genes; Killer Cells, Natural; Lu | 1983 |
Cells of origin of lung tumors in mice.
Topics: Animals; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Urethane | 1983 |
Enhancement of lung tumor formation in mice by dietary butylated hydroxytoluene: dose-time relationships and cell kinetics.
Topics: Animals; Autoradiography; Body Weight; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Di | 1983 |
Pharmacologic and genetic studies on the modulatory effects of butylated hydroxytoluene on mouse lung adenoma formation.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Lung; Lung Neoplasms; Mice; Mice, Inbred Strains; Oils; | 1984 |
Induction of persistent hypersensitivity to lung tumorigenesis by in utero X-radiation in mice.
Topics: Animals; Female; Fetus; Lung; Lung Neoplasms; Mice; Mice, Inbred ICR; Pregnancy; Urethane | 1984 |
Establishment of epithelial cell strains from normal adult mouse lung resembling a urethane-induced lung adenoma cell strain and a metastasizing mouse lung carcinoma cell line.
Topics: Adenoma; Animals; Carcinoma; Cell Division; Cell Line; Dexamethasone; Female; Lung; Lung Neoplasms; | 1984 |
Studies on the level of natural antibodies reactive with various tumor cells during urethane carcinogenesis in BALB/c mice.
Topics: Adenoma; Animals; Antibodies, Neoplasm; Cytotoxicity, Immunologic; Female; Immunity, Innate; Lung Ne | 1984 |
Localization of specific [3H]dexamethasone binding in urethan-induced mouse lung tumors.
Topics: Animals; Binding, Competitive; Cell Nucleus; Cytosol; Dexamethasone; Kinetics; Lung Neoplasms; Mice; | 1984 |
Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; DNA Repair; Ethylnitrosourea; Female; Hydroxamic Acids; | 1980 |
Diminution of chemically induced lung neoplasia in mice by phenobarbital pre-treatment.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Lung Neoplasms; Mice; Mice, Inb | 1982 |
Comparative inhibiting effects of methylxanthines on urethan-induced tumors, malformations, and presumed somatic mutations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Caffeine; DNA Repair; Lung Neoplasms; M | 1983 |
X-ray-induced germ-line mutation leading to tumors. Its manifestation in mice given urethane post-natally.
Topics: Animals; Carcinogens; Dose-Response Relationship, Radiation; Female; Germ Cells; Lung Neoplasms; Mal | 1983 |
Promotion of lung tumors in mice.
Topics: Animals; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Dose-Response Relationship, Drug | 1983 |
Modulation of the incidence of urethane induced mouse lung adenomas by butylated hydroxytoluene (BHT).
Topics: Adenoma; Animals; Biotransformation; Butylated Hydroxytoluene; Drug Interactions; Lung Neoplasms; Mi | 1983 |
Attempt to develop new mouse colony with high susceptibility to carcinogens.
Topics: Animals; Carcinogens; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ure | 1980 |
Inhibition of the activity of mouse natural killer cells by urethan.
Topics: Age Factors; Animals; Cytotoxicity, Immunologic; Immunity, Innate; Killer Cells, Natural; Lung Neopl | 1981 |
Susceptibility of various strains of mice to urethan-induced lung tumors and depressed natural killer cell activity.
Topics: Animals; Cytotoxicity, Immunologic; Killer Cells, Natural; Lung Neoplasms; Mice; Mice, Inbred A; Mic | 1981 |
Relationship of lung adenoma prevalence and growth rate to acute urethan dose and target cell number.
Topics: Adenoma; Animals; Cell Survival; Diet; Dose-Response Relationship, Drug; Female; Injections, Intrape | 1982 |
Relationship between urethan dose rate and adenoma latency: relevance of tumor growth rate and target cell number.
Topics: Adenoma; Animals; Cell Count; Cell Survival; Cell Transformation, Neoplastic; Diet; Dose-Response Re | 1982 |
[Morphological cardiovascular changes in the course of the neoplastic process in model RL-67 experimental tumor].
Topics: Animals; Carcinoma; Cardiovascular System; Lung Neoplasms; Mice; Mice, Inbred C57BL; Myocardium; Neo | 1982 |
Parental exposure to x rays and chemicals induces heritable tumours and anomalies in mice.
Topics: Animals; Female; Genes, Dominant; Lung Neoplasms; Male; Mice; Mutation; Neoplasms, Experimental; Neo | 1982 |
Reduced prevalence and growth rate of urethane-induced lung adenomas in ageing adult strain A mice.
Topics: Adenoma; Aging; Animals; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental; Organ | 1981 |
Modification of lung tumor development in A/J mice.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Carcinogens; Cell Division; Female; Lung Neoplasms; | 1981 |
Enhancement of tumor formation in mouse lung by dietary butylated hydroxytoluene.
Topics: Animals; Anisoles; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Drug Interactions; Ethoxyquin | 1981 |
Qualitative histological differences between transplacentally-induced lung tumors in young and aging mice.
Topics: Adenoma; Age Factors; Animals; Female; Fetus; Gestational Age; Lung Neoplasms; Lymphocytes; Mice; Mi | 1981 |
The effect of caffeine on two-stage skin carcinogenesis and on complete systemic carcinogenesis.
Topics: Adenoma; Animals; Caffeine; Drug Interactions; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Neopl | 1981 |
Ultrastructure of pulmonary tumors induced in rats by N-nitrosomethylurethane.
Topics: Adenoma; Animals; Female; Lung Neoplasms; Microscopy, Electron; Nitrosomethylurethane; Rats; Rats, I | 1981 |
Effect of lactate dehydrogenase virus on chemically induced mouse lung tumorigenesis.
Topics: Adenoma; Animals; Immunity; Lactate dehydrogenase-elevating virus; Lung Neoplasms; Male; Mice; Mice, | 1980 |
Comparative carcinogenicities and mutagenicities of vinyl carbamate, ethyl carbamate, and ethyl N-hydroxycarbamate.
Topics: Adenoma; Animals; Caffeine; Carbamates; Ducks; Ear Neoplasms; Female; Hydroxamic Acids; In Vitro Tec | 1980 |
Effect of the plant growth regulator, 2-chloroethylphosphonic acid, on spontaneous and chemically-induced lung tumorigenesis in strain A mice.
Topics: Adenoma; Animals; Cell Division; Cocarcinogenesis; DNA, Neoplasm; Female; Lung Neoplasms; Male; Mice | 1980 |
Inhibiting effects of antipain on urethane-induced lung neoplasia in mice.
Topics: Animals; Antipain; Caffeine; Female; Lung Neoplasms; Mice; Mice, Inbred ICR; Oligopeptides; Urethane | 1980 |
Possible in vivo formation of a carcinogenic substance from diethyl pyrocarbonate and ammonia.
Topics: Ammonia; Animals; Diethyl Pyrocarbonate; Female; Formates; Lung Neoplasms; Mice; Mice, Inbred Strain | 1980 |
Effect of commercial saccharin preparations on urethan-induced lung tumorigenesis in strain A mice.
Topics: Adenoma; Animals; Cocarcinogenesis; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimen | 1980 |
Inhibition of urethan induced lung tumour growth in strain A mice by 5-methyl cytidine.
Topics: Adenoma; Animals; Cell Division; Cell Survival; Cytidine; Lung Neoplasms; Mice; Neoplasms, Experimen | 1980 |
Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane.
Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Disease Models, Animal; Dose-Response Relationship, | 1995 |
Effects of cigarette smoke and disulfiram on tumorigenicity and clastogenicity of ethyl carbamate in mice.
Topics: Animals; Bone Marrow; Cytochrome P-450 Enzyme System; Disulfiram; Female; Lung Neoplasms; Male; Mice | 1995 |
Morphological changes and proliferative activity of alveolar epithelium in mouse lungs treated with urethan.
Topics: Animals; Cell Division; Epithelium; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nucleolus Org | 1995 |
Mutations of the Ki-ras protooncogene in 3-methylcholanthrene and urethan-induced and butylated hydroxytoluene-promoted lung tumors of strain A/J and SWR mice.
Topics: Animals; Base Sequence; Butylated Hydroxytoluene; Genes, ras; Lung Neoplasms; Male; Methylcholanthre | 1995 |
High frequency of K-ras mutations in spontaneous and vinyl carbamate-induced lung tumors of relatively resistant B6CF1 (C57BL/6J x BALB/cJ) mice.
Topics: Alleles; Animals; Base Sequence; Carcinogens; Codon; Crosses, Genetic; DNA Primers; Female; Genes, r | 1995 |
At least four genes and sex are associated with susceptibility to urethane-induced pulmonary adenomas in mice.
Topics: Adenoma; Animals; Base Sequence; Crosses, Genetic; Disease Susceptibility; Female; Genetic Markers; | 1994 |
Comparison of lung tumorigenesis induced by urethan in athymic nude mice and euthymic littermates.
Topics: Animals; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Lung Neoplasms; Male | 1994 |
[Role of sympathetic denervation in chemical carcinogenesis in the lungs in the pathogenesis of disorders of interleukin-1 production by alveolar macrophages].
Topics: Adenoma; Animals; Interleukin-1; Lung; Lung Neoplasms; Macrophages, Alveolar; Male; Mice; Mice, Inbr | 1993 |
Enhancement of tumor growth under short light/dark cycle in mouse lung.
Topics: Adenoma; Animals; DNA, Neoplasm; Lung Neoplasms; Male; Mice; Mice, Inbred A; Photoperiod; Urethane | 1994 |
Weak carcinogenicity of 2-hydroxyethyl carbamate in strain A mice: indication that this is not a proximal metabolite of ethyl carbamate.
Topics: Animals; Biotransformation; Carcinogens; Lung Neoplasms; Male; Mice; Urethane | 1994 |
Influence of low dietary iron and iron overload on urethan-induced lung tumors in mice.
Topics: Animals; Diet; Iron; Liver; Lung Neoplasms; Male; Mice; Random Allocation; Urethane | 1993 |
Comparison of dose-dependent enhancing effects of gamma-ray irradiation on urethan-induced lung tumorigenesis in athymic nude (nu/nu) mice ac (nu/+) littermates.
Topics: Animals; Dose-Response Relationship, Radiation; Gamma Rays; Lung Neoplasms; Mice; Mice, Inbred BALB | 1996 |
Diminished expression of CYP1A1 in urethane-induced lung tumors in strain A/J mice: analysis by in situ hybridization and immunohistochemical methods.
Topics: Animals; Blotting, Northern; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation, Enz | 1996 |
[Effect of radiation emitted from personal computer terminal on urethan-induced lung tumors in mice].
Topics: Animals; Computer Terminals; Female; Lung Neoplasms; Mice; Mice, Hairless; Microcomputers; Neoplasms | 1996 |
Expression of human Krev-1 gene in lungs of transgenic mice and subsequent reduction in multiplicity of ethyl carbamate-induced lung adenomas.
Topics: Adenoma; Animals; Gene Expression; Genes, ras; Genes, Tumor Suppressor; GTP-Binding Proteins; Humans | 1996 |
The activation of K-ras gene at an early stage of lung tumorigenesis in mice.
Topics: Animals; Carcinogens; Genes, ras; Lung Neoplasms; Male; Mice; Mutagenesis; Neoplasms, Experimental; | 1996 |
Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice.
Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Disease Progression; Exons; Genes, p53 | 1996 |
The inhibitory effect of vitamin E on pulmonary polyamine biosynthesis, cell proliferation and carcinogenesis in mice.
Topics: Animals; Biogenic Polyamines; Biomarkers, Tumor; Cell Division; Cyclooxygenase Inhibitors; Dinoprost | 1997 |
The inhibitory effect of vitamin E on K-ras mutation at an early stage of lung carcinogenesis in mice.
Topics: Animals; Blotting, Southern; Cell Division; Disease Models, Animal; Genes, ras; Lung; Lung Neoplasms | 1997 |
Genetic resistance to urethan-induced pulmonary adenomas in SMXA recombinant inbred mouse strains.
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Mice, Inbred Strains; Protein Kinase C; Recombination, Genet | 1997 |
The modulation effect of vitamin E on prostaglandin E2 level and ornithine decarboxylase activity at the promotion phase of lung tumorigenesis in mice.
Topics: Animals; Dinoprostone; Down-Regulation; Enzyme Induction; Lung Neoplasms; Male; Mice; Ornithine Deca | 1997 |
The inhibitory effect of vitamin E on arachidonic acid metabolism during the process of urethane-induced lung tumorigenesis in mice.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Hydroxyeicosa | 1997 |
Urban air pollution enhances the formation of urethane-induced lung tumors in mice.
Topics: Air Pollutants; Animals; Carcinogens; Female; Lung Neoplasms; Male; Mice; Urban Health; Urethane | 1997 |
Roles of the Pas1 and Par2 genes in determination of the unique, intermediate susceptibility of BALB/cByJ mice to urethane-induction of lung carcinogenesis: differential effects on tumor multiplicity, size and Kras2 mutations.
Topics: Animals; Codon; Crosses, Genetic; Female; Genes, ras; Genetic Predisposition to Disease; Lung Neopla | 1997 |
Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Body Weight; Carcinogens; Codon; Disease Susceptibilit | 1997 |
Mechanistic modeling of multiple tumorigenesis: an application to data on lung tumors in mice exposed to urethane.
Topics: Adenoma; Animals; Disease Models, Animal; Lung Neoplasms; Mice; Mice, Inbred A; Neoplasms, Experimen | 1997 |
Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice.
Topics: Adenoma; Animals; Carcinoma; Cell Transformation, Neoplastic; Codon; Disease Progression; DNA, Neopl | 1998 |
Reduction in transforming growth factor-beta type II receptor in mouse lung carcinogenesis.
Topics: Activin Receptors, Type I; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neop | 1998 |
Chemoprevention by N-acetylcysteine of urethane-induced clastogenicity and lung tumors in mice.
Topics: Acetylcysteine; Administration, Oral; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Body W | 1998 |
A model of multiple tumorigenesis allowing for cell death: quantitative insight into biological effects of urethane.
Topics: Animals; Binomial Distribution; Carcinogens; Cell Death; Confidence Intervals; Dose-Response Relatio | 1998 |
[Epithelium hyperplasia in cultured organotypic aggregates obtained from cells of mouse embryonic lungs].
Topics: Animals; Carcinogens; Cell Aggregation; Cells, Cultured; Epithelial Cells; Female; Histocytochemistr | 1998 |
Pulmonary fibrosis caused by N-methyl-N-nitrosourethane inhibits lung tumorigenesis by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
Topics: Animals; Base Sequence; Female; Genes, ras; Injections, Intraperitoneal; Injections, Subcutaneous; L | 1998 |
Investigation of lung tumour induction in C3H/HeH mice, with and without tumour promotion with urethane, following paternal X-irradiation.
Topics: Animals; Carcinogens; Child; Cocarcinogenesis; Dose-Response Relationship, Radiation; Fathers; Femal | 1998 |
At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice.
Topics: Adenoma; Animals; Chromosome Mapping; Crosses, Genetic; Female; Genetic Predisposition to Disease; L | 1998 |
Activation of extracellular signal-regulated kinase in lung tissues of mice treated with carcinogen.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Nucleus; Enzyme Activation; | 1999 |
Possible carcinogenic effects of X-rays in a transgenerational study with CBA mice.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cocarcinogenesis; Female; Genes, ras; Hematologic Neo | 1999 |
Preconception urethane or chromium(III) treatment of male mice: multiple neoplastic and non-neoplastic changes in offspring.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Chromium; DNA Damage; Female; Fertility; Lung Neoplasms; L | 1999 |
Susceptibility to urethane carcinogenesis of transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) and its modification by butylhydroxytoluene.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Carcinogens; Female; Genes, ras; Genetic Predisposition | 1999 |
[The study of correlation between the K-ras genotype and murine susceptibility to chemically induced lung neoplasms].
Topics: Animals; Carcinogens; Genes, ras; Genetic Predisposition to Disease; Lung Neoplasms; Mice; Mice, Inb | 1999 |
Surfactant protein C expression in urethane-induced murine pulmonary tumors.
Topics: Adenoma; Animals; Immunohistochemistry; In Situ Hybridization; Lung Neoplasms; Mice; Phenotype; Prot | 2000 |
[Search for Ki-ras codon 61 mutations in lung adenomas induced in neonatal BALB/c mice with 5-bromodesoxyuridine injection followed by urethane treatment].
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Codon; Disease Models, Animal; DNA, Neoplasm; Female; | 1999 |
[A comparison study on the sensitivity of lung tumor short-term induction test in three strains of mice].
Topics: Animals; Animals, Newborn; Carcinogens; Female; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, In | 1998 |
Carcinogen dose-dependent variation in the transgene mutation spectrum in urethane-induced lung tumors in transgenic mice carrying the human prototype c-Ha-ras gene.
Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Female; Genes, ras; Humans; Lung Neoplasms; | 2000 |
Promotive effect of diethylstilbestrol on urethan-induced mouse lung tumorigenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylstilbestrol; Drug Interactions; Female | 2000 |
Thymosinalpha1 is chemopreventive for lung adenoma formation in A/J mice.
Topics: Adenoma; Animals; Blood; Blotting, Western; Bronchi; Carcinogens; Female; Immunohistochemistry; Lung | 2000 |
The effect of exposure to a commercial 2,4-D herbicide formulation during gestation on urethan-induced lung adenoma formation in CD-1 mice.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenoma; Animals; Carcinogens; Female; Herbicides; Injections, Intra | 2000 |
Urban levels of air pollution modifies the progression of urethane-induced lung tumours in mice.
Topics: Adenoma; Air Pollutants; Air Pollution; Aneuploidy; Animals; Animals, Newborn; Brazil; Carcinogens; | 2000 |
Vitamin E inhibits cell proliferation and the activation of extracellular signal-regulated kinase during the promotion phase of lung tumorigenesis irrespective of antioxidative effect.
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinogens; Cell Division; Enzyme Activation; Female; | 2000 |
Interactions between N-acetylcysteine and ascorbic acid in modulating mutagenesis and carcinogenesis.
Topics: Acetylcysteine; Animals; Ascorbic Acid; Carcinogenicity Tests; Cell Transformation, Neoplastic; Chro | 2000 |
Enhanced tumorigenesis and reduced transforming growth factor-beta type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-beta1.
Topics: Animals; Blotting, Northern; Carcinogens; Crosses, Genetic; Female; Gene Amplification; Gene Dosage; | 2000 |
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethaso | 2000 |
Studies using structural analogs and inbred strain differences to support a role for quinone methide metabolites of butylated hydroxytoluene (BHT) in mouse lung tumor promotion.
Topics: Animals; Butylated Hydroxytoluene; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Femal | 2001 |
Aberrant expression of cyclin D1 in pulmonary proliferative lesions induced by high doses of urethane in transgenic mice carrying the human prototype c-H-ras gene.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Carcinogens; Female; Gene Expression Regulati | 2001 |
Telomerase activation and p53 mutations in urethane-induced A/J mouse lung tumor development.
Topics: Animals; Carcinogens; Enzyme Activation; Genes, p53; Lung Neoplasms; Mice; Mice, Inbred Strains; Mut | 2001 |
Delayed-type hypersensitivity and humoral immunity modulation by dietary lipids in a murine model of pulmonary tumorigenesis induced by urethan.
Topics: Adenocarcinoma; Animals; Antibody Formation; Carcinogens; Dietary Fats, Unsaturated; Disease Models, | 2001 |
Fine chromosomal localization of the mouse Par2 gene that confers resistance against urethane-induction of pulmonary adenomas.
Topics: Adenomatosis, Pulmonary; Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Crosses, Genet | 2001 |
Pulmonary tumors in germfree mice: induction with urethan.
Topics: Adenoviridae; Animals; Antibodies, Viral; Carcinogens; Encephalitis Viruses; Female; Germ-Free Life; | 1970 |
Influence of immunosuppression and immunorestoration on the formation of urethan-induced lung adenomas.
Topics: Adenoma; Animals; Antilymphocyte Serum; Carcinogens; Disease Susceptibility; Immunocompromised Host; | 1970 |
Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
Topics: Adenoma; Animals; Bronchi; Carcinogenicity Tests; Carcinogens; Carcinoma; Cocarcinogenesis; Disease | 2001 |
Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.
Topics: Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Crosses, Genetic; DNA Mutational An | 2001 |
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Pred | 2002 |
Quantitative trait loci that regulate susceptibility to both butylated hydroxytoluene-induced pulmonary inflammation and lung tumor promotion in CXB recombinant inbred mice.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Chromosome Mapping; Genetic Predisposition to Diseas | 2002 |
Cancer modifier alleles inhibiting lung tumorigenesis are common in inbred mouse strains.
Topics: Adenoma; Alleles; Animals; Carcinogens; Gene Dosage; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, | 2002 |
Partial inhibition of primary lung tumourigenesis by tetramisole.
Topics: Animals; Anticarcinogenic Agents; Female; Lung Neoplasms; Male; Mice; Regression Analysis; Tetramiso | 1977 |
[Serum desoxyribonuclease and hexokinase activity in mice exposed to urethane and certain pesticides].
Topics: Adenoma; Administration, Oral; Animals; Carcinogens; Deoxyribonucleases; Enzyme Activation; Fungicid | 1975 |
The influence of nutritional factors on pulmonary adenomas in mice.
Topics: Adenoma; Animals; Body Weight; Choline; Inositol; Lung Neoplasms; Mice; Mice, Inbred Strains; Niacin | 1977 |
Activities of four glycolytic enzymes (HK, PFK, PK, and LDH) and isozymic pattern of LDH in mouse lung tumor induced by urethan.
Topics: Age Factors; Animals; Glycolysis; Hexokinase; Isoenzymes; L-Lactate Dehydrogenase; Lung; Lung Neopla | 1979 |
Clonal isolation of epithelial cells from mouse lung adenoma.
Topics: Adenoma; Aneuploidy; Animals; Cell Division; Cells, Cultured; Clone Cells; Hydrocortisone; Karyotypi | 1975 |
C-type virus particles in urethan-induced pulmonary and renal carcinomas, in cell-graft-transmitted carcinosarcomas, and in filtrate-induced lymphomas in mice.
Topics: Adenocarcinoma, Papillary; Animals; Carcinosarcoma; Kidney Neoplasms; Lung Neoplasms; Lymphoma; Mice | 1976 |
Comparison of tumour susceptibility among various organs of foetal, young and adult ICR/Jcl mice.
Topics: Aging; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Fe | 1976 |
Protein phosphorylation in normal and neoplastic development. Cyclic AMP-dependent protein kinase activity in urethane-induced pulmonary tumours.
Topics: Animals; Cyclic AMP; Cytosol; Lung; Lung Neoplasms; Mice; Neoplasms, Experimental; Protein Kinases; | 1977 |
Effect of reovirus infection on pulmonary tumor response to urethan in strain A mice.
Topics: Adenoma; Animals; Immunity; Immunosuppression Therapy; Interferons; Lung Neoplasms; Male; Mice; Mice | 1978 |
Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate.
Topics: Adenoma; Animals; Biotransformation; Carcinogens; Female; In Vitro Techniques; Lung Neoplasms; Mice; | 1978 |
Induction of lymphomas by urethane in combination with diethylstilboestrol in CFLP mice.
Topics: Animals; Diethylstilbestrol; Drug Synergism; Lung Neoplasms; Lymphoma; Male; Mice; Mice, Inbred Stra | 1979 |
Histopathological studies on experimentally induced pulmonary, pleural and peritoneal neoplasms in mice by intraperitoneal injection of chrysotile asbestos and N-methyl-N-nitrosourethane.
Topics: Adenocarcinoma; Animals; Asbestos; Female; Injections, Intraperitoneal; Lung Neoplasms; Male; Mice; | 1979 |
Tumor development in lung of ddY mice following transplacental exposure to 1-ethyl-1-nitrosourea.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Gestational Age; Injections, Intraperitoneal; Injections | 1979 |
Enhancement of adenoma formation in mouse lung by butylated hydroxytoluene.
Topics: Adenoma; Animals; Butylated Hydroxytoluene; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred | 1979 |
Effects of prolactin and suppression of prolactin secretion on experimental tumours of lung and muscle in mice.
Topics: Animals; Bromocriptine; Lung Neoplasms; Male; Mice; Moloney murine leukemia virus; Neoplasms, Experi | 1977 |
Transplacental lung tumorigenesis in the athymic mouse.
Topics: Adenoma; Animals; Antigens, Neoplasm; Female; Immunity; Lung Neoplasms; Male; Maternal-Fetal Exchang | 1978 |
Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice.
Topics: Adenoma; Animals; Caffeine; DNA; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experi | 1978 |
Toxicity of butylated hydroxytoluene in mouse following oral administration.
Topics: Adenoma; Administration, Oral; Animals; Butylated Hydroxytoluene; Cresols; DNA; Drug Interactions; L | 1978 |
Two crops of primary lung tumors in BALB/c mice after a single transplacental exposure to urethane.
Topics: Adenoma; Age Factors; Animals; Female; Gestational Age; Lung Neoplasms; Male; Maternal-Fetal Exchang | 1978 |
[Lower urethane carcinogenicity for the lungs of thymus-free nude mice in comparison with immunologically normal littermate mice].
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Thymus Gland; Urethane | 1978 |
Effect of butylated hydroxytoluene and paraquat on urethan tumorigenesis in mouse lung.
Topics: Animals; Butylated Hydroxytoluene; Cresols; Drug Synergism; Female; Lung Neoplasms; Mice; Paraquat; | 1978 |
Report from Sloan-Kettering Institute: environmental carcinogenesis.
Topics: Animals; Carcinogens; Cyclic N-Oxides; Drug Interactions; Environmental Exposure; Female; Genital Ne | 1978 |
[The relationship between the activity of microsomal enzymes and pulmonary carcinogenesis in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Barbital; Chlorpromazine; | 1976 |
Murine pulmonary adenoma bioassay of potentially effective agents against slow-growing solid tumors.
Topics: Adenoma; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; | 1977 |
Enhancement of urethan tumorigenesis in mouse lung by butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; Cell Division; Cell Nucleus; Cresols; DNA, Neoplasm; Drug Adminis | 1977 |
Effect of inhaled plutonium dioxide on development of urethan-induced pulmonary adenomas.
Topics: Adenoma; Administration, Intranasal; Animals; Lung; Lung Neoplasms; Mice; Neoplasms, Experimental; P | 1977 |
Dextramycine (the dextraisomer of chloramphenicol) as an inhibitor of the induction of lung adenomas in mice.
Topics: Adenoma; Animals; Chloramphenicol; Isomerism; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neopl | 1977 |
[Effect of the tissue-specific lung adhesive factor on the urethane induction of pulmonary adenomas in mice].
Topics: Adenoma; Animals; Biological Products; Cell Nucleus; Dose-Response Relationship, Drug; Lung; Lung Ne | 1977 |
Cell kinetics of urethane-induced murine pulmonary adenomas: III. Implications of the disparity between the rates of entry into DNA synthesis and into mitosis.
Topics: Adenoma; Animals; Cell Cycle; Cell Nucleus; DNA, Neoplasm; Lung Neoplasms; Male; Metaphase; Mice; Mi | 1977 |
Environmental factors in the origin of cancer and estimation of the possible hazard to man.
Topics: Animals; Diethylstilbestrol; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation | 1975 |
Cell kinetics of urethane induced murine pulmonary adenomata: I. The growth rate.
Topics: Adenoma; Animals; Cell Division; Colchicine; DNA, Neoplasm; Female; Lung Neoplasms; Male; Mice; Mice | 1975 |
Letter: Transmission of tumors and malformations to the next generation of mice subsequent to urethan treatment.
Topics: Abnormalities, Drug-Induced; Animals; Carcinogens; Female; Lung Neoplasms; Male; Maternal-Fetal Exch | 1975 |
[Experimetal study of pulmonary emphysema and lung tumor (1)].
Topics: Animals; Female; Lung Neoplasms; Nitrosomethylurethane; Papain; Pulmonary Emphysema; Rats; Urethane | 1975 |
Biological studies on the effect of DNA extracted from urethan treated mice.
Topics: Adenocarcinoma; Animals; Animals, Newborn; DNA; Embryo, Mammalian; Fatty Liver; Female; Lung Neoplas | 1975 |
On the influence of chloramphenicol on the induction of lung adenomas by urethane in mice.
Topics: Adenoma; Animals; Chloramphenicol; Drug Interactions; Female; Lung Neoplasms; Male; Mice; Mice, Inbr | 1975 |
Hydantoin immunosuppression and carcinogenesis.
Topics: Adenoma; Animals; Concanavalin A; Female; Immune Adherence Reaction; Immunity; Immunosuppression The | 1975 |
Acyltransferases and the biosynthesis of pulmonary surfactant lipid in adenoma alveolar type II cells.
Topics: Acyltransferases; Adenoma; Animals; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Microsomes; N | 1975 |
Cell kinetics of urethane-induced murine pulmonary adenomata: II, the growth fraction and cell loss factor.
Topics: Adenoma; Age Factors; Animals; Cell Survival; Kinetics; Lung Neoplasms; Male; Mice; Mitosis; Neoplas | 1976 |
Relationship between antigenicity and morphology of murine lung adenomata.
Topics: Adenoma; Animals; Antigens, Neoplasm; Cell Survival; Cortisone; Cytotoxicity Tests, Immunologic; Fem | 1976 |
Test for carcinogenicity of metallic compounds by the pulmonary tumor response in strain A mice.
Topics: Adenoma; Animals; Female; Lead; Lung Neoplasms; Male; Manganese Poisoning; Metals; Mice; Molybdenum; | 1976 |
Tumor formation and sister chromatid exchange induction by ethyl carbamate: relationships among non-pregnant murine females, gravid dams, and transplacentally exposed offspring.
Topics: Adenoma; Animals; Cell Cycle; Cell Death; Female; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Mic | 1992 |
Lung adenoma development and NK activity in mice treated with multiple carcinogens.
Topics: Adenoma; Animals; Diethylnitrosamine; Female; Killer Cells, Natural; Lung Neoplasms; Methylnitrosour | 1992 |
The effect of a commercial 2,4-D formulation on chemical- and viral-induced tumor production in mice.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenoma; Animals; Cell Transformation, Viral; Drug Synergism; Leukem | 1992 |
Multiple molecular alterations in mouse lung tumors.
Topics: Animals; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, ras; Genes, Retinoblasto | 1992 |
Comparison of Ki-ras gene mutation among simultaneously occurring multiple urethan-induced lung tumors in individual mice.
Topics: Amino Acid Sequence; Animals; DNA, Neoplasm; Exons; Female; Genes, ras; Lung Neoplasms; Male; Mice; | 1992 |
Two-step carcinogenesis induced by neonatal exposure to 5-bromo-2'- deoxyuridine and subsequent administration of urethan in BALB/c mice.
Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Body Weight; Bromodeoxyuridine; Cocarcinogenesis | 1992 |
1,N6-ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate.
Topics: Adenosine; Animals; Ditiocarb; Epoxy Compounds; Ethers, Cyclic; Female; Liver Neoplasms, Experimenta | 1990 |
The effects of Tordon 202c exposure on urethan-induced lung adenoma formation in female CD-1 mice.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenoma; Animals; Dose-Response Relationship, Drug; Drinking; Drug S | 1991 |
Effect of ethanol on the induction of lung tumours by ethyl carbamate in mice.
Topics: Adenoma; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Lung Neoplasms; Mice; Urethane | 1991 |
Urethan (ethyl carbamate) is an effective promoter of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis in mouse skin two-stage experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Cocarcinogenesis; Female; Lung Neoplasms; Male; | 1991 |
Quantitative risk assessment of carcinogenicity of urethane (ethyl carbamate) on the basis of long-term oral administration to B6C3F1 mice.
Topics: Adenoma; Animals; Carcinogens, Environmental; Carcinoma; Chi-Square Distribution; Dose-Response Rela | 1991 |
Usefulness of medium-term bioassay determining formations of pulmonary adenoma in NIH(GP) mice for finding anticarcinogenic agents from natural products.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Aflatoxin B1; Animals; Antineoplastic Agents, Phytogenic; | 1991 |
Quantitative analysis of genetic susceptibility to liver and lung carcinogenesis in mice.
Topics: Age Factors; Animals; Disease Susceptibility; Female; Liver Neoplasms, Experimental; Lung Neoplasms; | 1991 |
Inhibition by wine of tumorigenesis induced by ethyl carbamate (urethane) in mice.
Topics: Adenoma; Administration, Oral; Animals; Dose-Response Relationship, Drug; Ethanol; Liver Neoplasms, | 1991 |
Carcinogenicity of sublimed urethane in mice through the respiratory tract.
Topics: Administration, Inhalation; Animals; Carcinogenicity Tests; Dose-Response Relationship, Drug; Female | 1990 |
Chronic ethanol intake and reduction of lung tumours from urethane in strain A mice.
Topics: Adenoma; Animals; Dose-Response Relationship, Drug; Drug Interactions; Eating; Ethanol; Female; Live | 1990 |
Pulmonary adenomas in A/J mice treated with silica.
Topics: Adenoma; Animals; Lung Neoplasms; Male; Mice; Mice, Inbred A; Silicon Dioxide; Urethane | 1990 |
Activated Ki-ras proto-oncogene in spontaneously transformed and chemical tumor-derived cell lines related to the mouse lung alveologenic carcinoma.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Base Sequence; Cell Transformation, Neoplasti | 1990 |
Ki-ras activation and expression in transformed mouse lung cell lines.
Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Cell Division; Cell Transformation, Neoplastic; Gen | 1990 |
Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas.
Topics: Adenocarcinoma; Adenoma; Animals; Codon; Gene Expression; Lung Neoplasms; Mice; Mice, Inbred A; Muta | 1990 |
Tumorigenicity of nickel subsulfide in Strain A/J mice.
Topics: Adenoma; Administration, Inhalation; Animals; Carcinogens; Injections, Intraperitoneal; Lung Neoplas | 1990 |
Effect of glycerol on cell kinetics and tumorigenesis in mouse lung following urethan administration.
Topics: Animals; Bronchi; Cell Cycle; Cell Transformation, Neoplastic; DNA; Epithelium; Glycerol; Interphase | 1990 |
Comparison of chronic inhalation effects in rodents after long-term exposure to either coal oven flue gas mixed with pyrolized pitch or diesel engine exhaust.
Topics: Administration, Inhalation; Animals; Body Burden; Coal; Cocarcinogenesis; Cricetinae; Female; Lung; | 1986 |
A cell culture model of chemically and spontaneously derived mouse lung alveologenic carcinoma.
Topics: Adenoma; Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Female; Fibronectins; Ker | 1988 |
Preventing effect of "liuwei dihuang decoction" on esophageal carcinoma.
Topics: Animals; Cell Nucleus; Cyclic AMP; Cyclophosphamide; Drugs, Chinese Herbal; Epithelium; Esophageal N | 1989 |
A metabolite of butylated hydroxytoluene with potent tumor-promoting activity in mouse lung.
Topics: Animals; Biotransformation; Butylated Hydroxytoluene; Carcinogens; Cocarcinogenesis; Lung; Lung Neop | 1989 |
Experimental analysis of the effects of cyclosporine on the induction and growth of epithelial tumors.
Topics: Adenoma; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Divi | 1989 |
The H-2 class II genes and the susceptibility to the development of pulmonary adenoma in mice.
Topics: Adenoma; Animals; Genes, MHC Class I; Genetic Predisposition to Disease; Haplotypes; Lung Neoplasms; | 1989 |
Enhanced malignant phenotype of urethane-induced lung adenoma associated with sialoadenectomy in BALB/c mice.
Topics: Adenoma; Animals; Epidermal Growth Factor; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Subman | 1989 |
Inhibiting effects of nicotinamide on urethane-induced malformations and tumors in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Dose-Response Relationship, Drug; Fem | 1988 |
Changes in cyclic adenosine 3':5'-monophosphate-dependent protein kinases during the progression of urethan-induced mouse lung tumors.
Topics: Affinity Labels; Animals; Calcium; Cyclic AMP; Female; Hydrogen-Ion Concentration; Isoenzymes; Light | 1985 |
The effect of cadmium on chemical- and viral-induced tumor production in mice.
Topics: Adenoma; Animals; Cadmium; Female; Immunosuppressive Agents; Kidney; Leukemia Virus, Murine; Leukemi | 1986 |
The effect of lead on chemical- and viral-induced tumor production in mice.
Topics: Adenoma; Animals; Female; Immunosuppression Therapy; Lead; Leukemia Virus, Murine; Leukemia, Experim | 1987 |
H-2-controlled genetic susceptibility to pulmonary adenomas induced by urethane and 4-nitroquinoline 1-oxide in A/Wy congenic strains.
Topics: 4-Nitroquinoline-1-oxide; Adenoma; Animals; H-2 Antigens; Lung Neoplasms; Mice; Mice, Inbred Strains | 1987 |
[Effect of glucuronic acid on the carcinogenic action of urethane, dibutylnitrosamine and 7,12-dimethyl[A]anthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Glucuronates; Glucuronic Acid; Lung Neoplasm | 1988 |
N-nitrosocimetidine as a modifier of chemically-initiated tumors in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cimetidine; Cocarcinogenesis; Lung Neoplasms; Mice; Neopl | 1988 |
The immune system during the precancer period: naturally-occurring tumor reactive monoclonal antibodies and urethane carcinogenesis.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Immunity, Innate; Leukemia L5178; Lung Neopla | 1988 |
Urethane-induced lung adenomas in the first-generation progeny of irradiated male mice.
Topics: Adenoma; Animals; DNA; DNA Damage; Leukemia, Myeloid; Litter Size; Lung Neoplasms; Male; Mammary Neo | 1988 |
Chemopreventive effect of antineoplaston A-10 on urethane-induced pulmonary neoplasm in mice.
Topics: Adenoma; Animals; Benzeneacetamides; Female; Lung Neoplasms; Mice; Piperidines; Piperidones; Urethan | 1988 |
Individual and strain differences in patterns of long-term persistence of urethane-induced sister chromatid exchanges (SCEs) in mouse lymphocytes and their relation to carcinogen susceptibility.
Topics: Adenoma; Animals; Female; Lung Neoplasms; Lymphocytes; Lymphoma; Mice; Mice, Inbred C57BL; Neoplasms | 1988 |
Influence of copper and zinc on urethan-induced adenoma development in mice.
Topics: Adenoma; Administration, Oral; Animals; Copper; Female; Lung Neoplasms; Mice; Sleep; Urethane; Zinc | 1988 |
Alterations in urethan-induced adenoma formation in mice exposed to selenium and nickel.
Topics: Adenoma; Animals; Body Weight; Cocarcinogenesis; Drinking; Female; Lung Neoplasms; Mice; Nickel; Sel | 1987 |
Modification by ozone of lung tumor development in mice.
Topics: Air Pollution; Animals; Cocarcinogenesis; Drug Interactions; Humans; Lung Neoplasms; Male; Mice; Mic | 1987 |
Cellular derivation of lung tumors in sensitive and resistant strains of mice: results at 28 and 56 weeks after urethan treatment.
Topics: Adenoma; Animals; Immunity, Innate; Lung Neoplasms; Mice; Mice, Inbred Strains; Time Factors; Uretha | 1987 |
Effect of red ginseng on natural killer cell activity in mice with lung adenoma induced by urethan and benzo(a)pyrene.
Topics: Adenoma; Animals; Animals, Newborn; Benzo(a)pyrene; Cell Line; Cytotoxicity, Immunologic; Killer Cel | 1987 |
Antiteratogenic and anticarcinogenic effects of X-rays in urethane-treated NMRI mice.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Chloroquine; Female; Lung Neoplasms; Male; Mice | 1987 |
The effect of arsenic on urethan-induced adenoma formation in Swiss mice.
Topics: Adenoma; Animals; Arsenates; Arsenic; Arsenites; Body Weight; Disease Models, Animal; Drinking; Fema | 1987 |
Alterations in urethan-induced adenoma formation in mice exposed to selenium and arsenic.
Topics: Adenoma; Animals; Arsenic; Body Weight; Drinking; Drug Interactions; Female; Lung Neoplasms; Mice; S | 1987 |
Chemopreventive and antineoplastic activity of N-homocysteine thiolactonyl retinamide.
Topics: Animals; Antineoplastic Agents; Homocysteine; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbred C57 | 1987 |
Separation of early diffuse alveolar cell proliferation from enhanced tumor development in mouse lung.
Topics: Animals; Butylated Hydroxytoluene; Cell Division; Hyperplasia; Lung Neoplasms; Male; Methylcholanthr | 1986 |
Tumorigenesis and genotoxicity of ethyl carbamate and vinyl carbamate in rodent cells.
Topics: Animals; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Female; Lung Neoplasms; | 1986 |
Genetic variation in the proliferation of murine pulmonary type II cells: basal rates and alterations following urethan treatment.
Topics: Animals; Cell Division; Female; Lung; Lung Neoplasms; Mice; Mice, Inbred Strains; Species Specificit | 1986 |
Inhibition of urethan-induced lung tumors in mice by dietary N-acetylcysteine.
Topics: Acetylcysteine; Animals; Diet; Glutathione; Lung Neoplasms; Male; Mice; Urethane | 1986 |
Lung tumor induction in strain A mice with benzotrichloride.
Topics: Animals; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; | 1986 |
Genetic influence on type 2 or Clara cell origin of pulmonary adenomas in urethan-treated mice.
Topics: Adenoma; Age Factors; Animals; Butylated Hydroxytoluene; Lung Neoplasms; Lymphocytes; Mice; Mice, In | 1985 |
Susceptibility to urethan-induced pulmonary adenomas between A/J and C57BL/6J mice: use of AXB and BXA recombinant inbred lines indicating a three-locus genetic model.
Topics: Adenoma; Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Female; Lung Neoplasms; Male; Mice; | 1985 |
In vivo formation of a carcinogenic substance from diethyl pyrocarbonate in the presence of ammonia.
Topics: Ammonia; Animals; Biotransformation; Chromatography, Thin Layer; Diethyl Pyrocarbonate; Female; Form | 1985 |
Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice.
Topics: Aerosols; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Epithelium; Hyperplasia; Lung Neoplas | 1985 |
Effects of strain and age on prophylaxis and co-carcinogenesis of urethan-induced mouse lung adenomas by butylated hydroxytoluene.
Topics: Adenoma; Age Factors; Animals; Butylated Hydroxytoluene; Cocarcinogenesis; Lung Neoplasms; Mice; Mic | 1986 |
Inhibition of mouse lung tumor development by hyperoxia.
Topics: Animals; Body Weight; Cell Division; Dose-Response Relationship, Drug; Free Radicals; Lung; Lung Neo | 1986 |
[Morphogenetic characteristics of the aggregates formed in epithelial and mesenchymal recombinations of the lungs from intact and urethane-exposed mouse embryos].
Topics: Animals; Culture Techniques; Epithelium; Female; Hyperplasia; Lung; Lung Neoplasms; Mesoderm; Metapl | 1985 |
Cell kinetics in mouse lung following administration of carcinogens and butylated hydroxytoluene.
Topics: Animals; Autoradiography; Butylated Hydroxytoluene; DNA; Drug Synergism; Hyperplasia; Injections, In | 1985 |
[Demonstration by immunofluorescence of group-specific antigens of the C particles in spontaneous tumors of the lung and those induced by chemicl carcinogens in BALBc mice].
Topics: Animals; Antigens; Cytoplasmic Granules; Epitopes; Fluorescent Antibody Technique; Hydrazines; Inclu | 1972 |
Increased incidence of urethane induced lung adenomata by autosensitized lymphocytes.
Topics: Adenoma; Animals; Autoantibodies; Autoantigens; Concanavalin A; Female; Fibroblasts; Graft vs Host R | 1974 |
[On crystalline amyloid].
Topics: Amyloidosis; Animals; Cytoplasmic Granules; Injections, Intraperitoneal; Kidney Glomerulus; Liver Ne | 1965 |
Biological tests of carcinogenic activity.
Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla | 1968 |
Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice.
Topics: Alkylating Agents; Allyl Compounds; Animals; Antineoplastic Agents; Biological Assay; Busulfan; Buta | 1973 |
[Histochemical study of induced and grafted pulmonary tumors in mice].
Topics: Animals; Histocytochemistry; In Vitro Techniques; Lung Neoplasms; Mice; Neoplasm Transplantation; Ne | 1966 |
[Pulmonary adenoma in the Swiss mouse receiving urethane. V. Action of various urethane antagonists].
Topics: Aminobenzoates; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Sulfanilamides; Urethane | 1967 |
[Production of stomach and pancreatic cancer in the guinea pig using methylnitroso-urea and methylnitroso-urethane].
Topics: Animals; Body Weight; Carcinoma; Ear Neoplasms; Guinea Pigs; Laryngeal Neoplasms; Leukemia; Lung Neo | 1968 |
Organ culture of lung tissue, as a method of the study of lung tumours and the blastomogenic action of substances that can induce them.
Topics: Adenoma; Animals; Carcinogens; Culture Techniques; Embryo, Mammalian; Female; Lung; Lung Neoplasms; | 1968 |
[Mediastinal lymphoma of Swiss mice receiving urethane. X. Microscopic study of a series of germ-free animals receiving it for 10 weeks].
Topics: Adenoma; Animals; Chemical and Drug Induced Liver Injury; Germ-Free Life; Hyperplasia; Leukocytosis; | 1970 |
[Pulmonary adenoma in Swiss mice receiving urethane. 8. Action of phenobarbital].
Topics: Adenoma; Animals; Drug Antagonism; Female; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Phen | 1970 |
[Pulmonary adenoma in Swiss mice receiving urethane. IX. Development of adenoma in young mice suckled by mothers subjected to the poison].
Topics: Adenoma; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Lung Neoplasms; Mice | 1970 |
[Ultrastructural aspect of lesions induced in the mouse lung by N-nitroso-N-methylurethane. With an attempt at interpretation of crystalline cellular inclusions].
Topics: Animals; Carcinogens; Lung; Lung Neoplasms; Mice; Microscopy, Electron; Nitroso Compounds; Pulmonary | 1972 |
The protective effect of hydantoin treatment on carcinogenesis.
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Mice, Inbred Strains; Phenytoin; Urethane | 1974 |
The neonatal and infant age periods as biologic factors which modify multicarcinogenesis by urethan.
Topics: Age Factors; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Eye Neoplasms; Female; Liver Neop | 1967 |
The effect of gonadectomy on the development of hepatomas induced by urethan.
Topics: Adenoma; Adrenal Gland Diseases; Animals; Carcinoma, Hepatocellular; Castration; Female; Gonadal Ste | 1967 |
The prenatal exposure of mice to urethan and the consequent development of tumors in various tissues.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Liver Neoplasms; L | 1967 |
Enhancement of urethan induction of hepatomas in mice by prior partial hepatectomy.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Hepatectomy; Leukemia, Experimental; Liver Neoplasm | 1968 |
[The oncogenic effect of urethane and myeloid chlorleukemia virus on adult mice].
Topics: Adenoma; Age Factors; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Leukemia Virus, Murin | 1970 |
[A new animal for experimental oncologic research--the Dzhungarian hamster].
Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel | 1970 |
Effect of partial hepatectomy on tumor incidence in BALB-c mice treated with urethan.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Division; Female; Hepatectomy; Leukemia, Exper | 1970 |
Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds.
Topics: Adenoma; Animals; Animals, Newborn; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Carcinoma, Hep | 1970 |
Comparative studies on the kinetics of the neoplastic competence in mice.
Topics: Adenoma; Age Factors; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Female; Lacrimal Apparat | 1970 |
Perinatal carcinogenesis by urethan.
Topics: Adenoma; Age Factors; Animals; Carcinoma, Hepatocellular; Cystadenoma; Female; Gestational Age; Lacr | 1971 |
Transplacental blastomogenesis in organ cultures of embryonic lung tissue.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Carcinogens; Female; Hyperplasia; Injections, | 1971 |
[Isolation of C particles from 3 cell lines in vitro from primary tumors of the lung induced with urethane in BALBc mice].
Topics: Adenocarcinoma, Papillary; Animals; Cell Line; Hydrazines; In Vitro Techniques; Inclusion Bodies, Vi | 1972 |
Transplacental carcinogenesis by urethan in mice: teratogenesis and carcinogenesis in relation to organogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Carcinoma, Hepatocellular; Cystadenoma; Endometrial Hyperplasi | 1972 |
[Comparative study of the lipid fractions and 32 P-orthophosphate incorporation in individual phospholipids from experimental lung tumors and from normal lungs].
Topics: Animals; Chromatography, Thin Layer; Gels; Injections, Intraperitoneal; Lipid Metabolism; Lung; Lung | 1972 |
Carcinogenesis by urethan via mother's milk and its enhancement of transplacental carcinogenesis in mice.
Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Cystadenoma; Female; Gestational | 1973 |
Reaction of mice on infection with mycoplasma and leukosis viruses.
Topics: Acholeplasma laidlawii; Animals; Female; Hybridization, Genetic; Leukemia Virus, Murine; Leukemia, E | 1973 |
The effect of long-term exposure to DDT on CF-1 MICE.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DDT; Dose-Response Relationship, Drug; Female; Fert | 1972 |
Effects of partial hepatectomy on carcinogenicity, metabolism, and binding to DNA of ethyl carbamate.
Topics: Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Croton Oil; DNA; Female; Hemangioma; Hepat | 1974 |
Suppression of chemically induced pulmonary tumors by treatment of strain A mice with murine sarcoma virus.
Topics: Adenoma; Animals; Female; Gammaretrovirus; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inb | 1974 |
Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N-methyl-N-nitrosourethan during pregnancy or lactation.
Topics: Abnormalities, Drug-Induced; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Fetus; Gestati | 1974 |
Increased incidence of urethan-induced lung adenomas in neonatally thymectmized mice challenged with lymphoid cells.
Topics: Adenoma; Animals; Animals, Newborn; Antibody Formation; Graft vs Host Reaction; Leukocyte Count; Lun | 1969 |
The use of a combination of cytostatics with substances influencing neuro-humoral regulation (K6) in the treatment of lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Bronchogenic; Drug Synergism; Hu | 1971 |
[Lung organ cultures as a model for the study of mouse sensitivity to urethane action].
Topics: Adenoma; Age Factors; Animals; Cell Transformation, Neoplastic; Culture Techniques; Drug Resistance; | 1974 |
[Inhibition of urethane carcinogenesis by antioxidants and carbon tetrachloride].
Topics: Adenoma; Administration, Oral; Animals; Antioxidants; Carbon Tetrachloride; Cell Transformation, Neo | 1974 |
Sensitivity of a lung cell in the developing mouse embryo to tumor induction by urethan.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Differentiation; Dose-Response Relationship, Dru | 1974 |
[Stimulation of pulmonary tumorigenesis by urethane in BALB/c mice pretreated with soluble antigens extracted from a mammary tumor in ascitic form (ATPC+) by use of hypertonic solutions of potassium chloride].
Topics: Animals; Antigens, Neoplasm; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BAL | 1974 |
[Stimulation of pulmonary tumorigenesis by urethane in BALB/c mice pretreated with soluble antigens extracted from a tumor of the lung is ascitic form (LTA) by use of hypertonic solution of potassium chloride].
Topics: Animals; Antigens, Neoplasm; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Pot | 1974 |
[Lung tumors developing under the effect of urethane and influenza virus].
Topics: Adenoma; Animals; Carcinogens; Lung Neoplasms; Mice; Neoplasms, Experimental; Oncogenic Viruses; Ort | 1974 |
Immunogenicity and immunosensitivity of urethane-induced murine lung adenomata, in relation to the immunological impairment of the primary tumour host.
Topics: Adenoma; Animals; Antibody-Producing Cells; Cortisone; Cross Reactions; Cytotoxicity Tests, Immunolo | 1973 |
The failure of intermediates of DNA synthesis to influence the initiation by urethane of skin tumours in mice.
Topics: Animals; DNA; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic | 1972 |
Induction of tumors by direct injection of carcinogen into mouse fetus.
Topics: Animals; Carcinogens; Female; Fetus; Injections; Lung Neoplasms; Methylcholanthrene; Mice; Neoplasms | 1972 |
Electron microscopic study of interstitial pneumonia, with special reference to alveolar epithelial cells.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Amphibians; Animals; Biopsy; Birds; Epithelium; Female; Humans | 1972 |
Radiotherapy of experimental lung tumors in the presence and absence of a radioprotective drug, S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721).
Topics: Adenoma; Animals; Dose-Response Relationship, Radiation; Lung Neoplasms; Male; Mice; Neoplasms, Expe | 1973 |
Inhibition of urethane-induced pulmonary adenomas by inhaled plutonium-239.
Topics: Adenoma; Animals; Cell Transformation, Neoplastic; Injections, Intraperitoneal; Lung Neoplasms; Male | 1973 |
Inhibition of chemical carcinogen-induced pulmonary neoplasia by butylated hydroxyanisole.
Topics: Adenoma; Animals; Anisoles; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Diet; Female; Lung Neopla | 1973 |
[Mechanical properties of normal tissue and lung adenomas in mice].
Topics: Adenoma; Animals; Cell Adhesion; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbred C57BL; Micromani | 1973 |
[Cellular cohesive forces in the pulmonary tissue of different lines of mice and their sensitivity to induction of lung tumors by urethane].
Topics: Adenoma; Animals; Cell Adhesion; Crosses, Genetic; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbre | 1973 |
[The sensitivity of mouse line A and C57Bl embryonic lung tissue to the transplacental action of urethane in tissue culture].
Topics: Adenoma; Animals; Female; In Vitro Techniques; Lung; Lung Neoplasms; Maternal-Fetal Exchange; Mice; | 1973 |
[Comparative evaluation of the blastomogenic action of a binary mixture of alkylcarbamates and its components].
Topics: Adenoma; Animals; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Urethane | 1973 |
Urethan-induced pulmonary adenoma as a tool for the study of surfactant biosynthesis.
Topics: Adenoma; Adenosine Triphosphate; Animals; Calcium; Carbon Radioisotopes; Carcinoma, Squamous Cell; C | 1973 |
The role of radiation biology in the evaluation of somatic hazards. What can the radiobiologist usefully do?
Topics: Animals; Environmental Exposure; Humans; Leukemia, Radiation-Induced; Lung Neoplasms; Maximum Allowa | 1973 |
Frequency and organ distribution of lung tumor metastases in CF-1 mice.
Topics: Animals; Carcinoma; Female; Heart Neoplasms; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Lung | 1974 |
Kinetics of alveolar epithelial hyperplasia in lungs of mice exposed to urethane. I. Quantitative analysis of cell populations.
Topics: Adenoma; Animals; Capillaries; Cell Count; Cell Division; Endothelium; Epithelial Cells; Female; Fib | 1974 |
An evaluation of the tumorigenicity of cyclophosphamide and urethan in newborn mice.
Topics: Animals; Animals, Newborn; Body Weight; Cyclophosphamide; Dose-Response Relationship, Drug; Female; | 1974 |
An analysis of the changing urethan response of the developing mouse embryo in relation to mortality, malformation, and neoplasm.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Embryo Implantation; Embryo, Mammalian; | 1974 |
The predictive value of skin allograft survival times during the development of urethan-induced lung adenomas in BALB-c mice.
Topics: Adenoma; Animals; Female; Histocompatibility; Immunity; Lung Neoplasms; Male; Mice; Neoplasms, Exper | 1970 |
[Effect of urethane and cortisone on carcinogenesis in lung isotransplants in mice].
Topics: Animals; Cortisone; Immunosuppressive Agents; Lung Neoplasms; Lung Transplantation; Mice; Neoplasms, | 1970 |
[Different susceptibility of the alveolar and tracheobronchial epithelia of BALB-c-Cb-Se mice to tumorigenesis induced with urethane in isogenic transplants].
Topics: Animals; Animals, Newborn; Epithelium; Lung Neoplasms; Lung Transplantation; Mice; Neoplasms, Experi | 1970 |
Study of the potential carcinogenicity of topical drug. Suggestions for a new experimental approach.
Topics: Adenocarcinoma; Administration, Topical; Animals; Anti-Inflammatory Agents; Bronchial Neoplasms; Car | 1971 |
[Variations of desoxyribonucleic acid activity of pulmonary tissue of the Swiss mouse treated with 3,4-benzopyrene of urethane].
Topics: Adenoma; Analysis of Variance; Animals; Animals, Newborn; Benzopyrenes; Carcinogens; DNA; Female; Lu | 1968 |
Suppression of urethan-induced lung adenomas in mice treated with trehalose-6,6-dimycolate (cord factor) and living bacillus Calmette Guérin.
Topics: Adenoma; Animals; BCG Vaccine; Glycolipids; Granuloma; Injections, Intraperitoneal; Injections, Intr | 1971 |
Improvement of lung tumor radiotherapy through differential chemoprotection of normal and tumor tissue.
Topics: Animals; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organothiophosph | 1972 |
Comparative study of carcinogenic activity of hydroxyurea and urethane in XVII-G mice.
Topics: Animals; Carcinogens; Hydroxyurea; Injections, Intraperitoneal; Injections, Subcutaneous; Lung Neopl | 1972 |
Tumour formation in mice by urethane administered with related carbamates.
Topics: Animals; Carbamates; Carcinoma; Carcinoma, Squamous Cell; Croton Oil; Drug Interactions; Esters; Inj | 1972 |
Alterations in cell proliferation in mouse lung following urethane exposure. 3. Effects of chronic exposure on type 2 alveolar epithelial cell.
Topics: Animals; Autoradiography; Body Weight; Cell Division; Drinking; Epithelial Cells; Epithelium; Lung N | 1972 |
Long-term toxicity studies of chlorpropham and propham in mice and hamsters.
Topics: Animals; Carbamates; Chlorpropham; Cricetinae; Female; Growth; Herbicides; Injections, Subcutaneous; | 1972 |
Demonstration of cellular immunity against urethan-induced lung adenomas of mice.
Topics: Adenoma; Animals; Antigens; Antigens, Neoplasm; Cross Reactions; Cytotoxicity Tests, Immunologic; Im | 1971 |
Alteration in cell proliferation in mouse lung following urethane exposure. II. Effects of chronic exposure on terminal bronchiolar epithelium.
Topics: Adenoma; Animals; Autoradiography; Bronchi; DNA; Environmental Exposure; Epithelial Cells; Epitheliu | 1971 |
Intracellular components of neoplastic and normal alveolar cells from mouse lungs: quantitative ultrastructural comparison.
Topics: Animals; Cell Nucleolus; Chromatin; Cytoplasm; Cytosol; Endoplasmic Reticulum; Female; Golgi Apparat | 1971 |
[Chemotherapy of malignant cancer using carbazilquinone].
Topics: Alanine Transaminase; Alkaline Phosphatase; Antineoplastic Agents; Aspartate Aminotransferases; Azir | 1971 |
Dose-response studies in experimentally induced lung tumours.
Topics: Adenocarcinoma; Adenoma; Air Pollution; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Carc | 1971 |
Urethan-induced lung tumors in mice: x-radiation dose dependent inhibition. USNRDL-TR-911.
Topics: Animals; Lung; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Radiation Effects; Urethane | 1965 |
Early alveolar cell mitotic activity and pulmonary tumor incidence in urethan treated x-irradiated mice. USNRDL-TR-68-51.
Topics: Animals; Lung Neoplasms; Male; Mice; Mitosis; Neoplasms, Experimental; Pulmonary Alveoli; Urethane | 1968 |
[Inhibitory action of the pre-treatment with phenobarbital on the pulmonary carcinogenic activity of ethyl urethane in mice].
Topics: Animals; Female; Lung Neoplasms; Male; Phenobarbital; Rats; Urethane | 1967 |
Modification of urethane-lung tumor incidence by low x-radiation doses, cortisone and transfusion of isogenic lymphocytes. NRDL-TR-69-1.
Topics: Cortisone; Lung Neoplasms; Lymphocyte Transfusion; Neoplasms, Experimental; Transplantation, Homolog | 1968 |
Histopathology of primary lung tumours in the mouse.
Topics: Animals; Benz(a)Anthracenes; Bronchi; Lung; Lung Neoplasms; Mice; Neoplasms, Experimental; Neoplasms | 1969 |
Utilization of newborn mice in the bioassay of chemical carcinogens.
Topics: Adenoma; Aflatoxins; Aniline Compounds; Animals; Animals, Newborn; Benzene Derivatives; Biological A | 1969 |
The oxidative enzyme pattern of the urethane-induced pulmonary adenoma.
Topics: Adenoma; Animals; Citric Acid Cycle; Female; Glutamate Dehydrogenase; Glycerolphosphate Dehydrogenas | 1969 |
Mouse mammary carcinogenesis by ethyl and butyl carbamates.
Topics: Animals; Carbamates; Female; Injections, Intraperitoneal; Lung Neoplasms; Mammary Neoplasms, Experim | 1969 |
[Comparison of various biochemical indices under normal conditions and during blastomogenesis in mice].
Topics: Adenoma; Animals; Deoxyribonucleases; Glucosephosphate Dehydrogenase; Lung Neoplasms; Mice; Rats; Ur | 1969 |
Lung tumor response in strain A mice as a quantitative bioassay of carcinogenic activity of some carbamates and aziridines.
Topics: Animals; Azirines; Biological Assay; Carbamates; Carcinogens; Lung Neoplasms; Mice; Urethane | 1969 |
[Transplacental effect of blastomogenic substances. Some further studies on organ cultures].
Topics: Adenoma; Animals; Benz(a)Anthracenes; Biphenyl Compounds; Carcinogens; Culture Techniques; Embryo, M | 1969 |
[Testing of dimetacrine and azapropazone in a carcinogen test on mice].
Topics: Acridines; Adenoma; Animals; Animals, Newborn; Anti-Inflammatory Agents; Antidepressive Agents; Carc | 1969 |
[The relationship of age to the sensitivity of mice to the blastomogenic effect of urethane].
Topics: Adenoma; Age Factors; Animals; Carcinogens; Lung Neoplasms; Mice; Urethane | 1969 |
Effect of actinomycin D and urethan on successive litters and generations of mice.
Topics: Abnormalities, Drug-Induced; Animals; Breeding; Dactinomycin; Female; Fetal Death; Lung Neoplasms; M | 1970 |
Lung tumor-bearing strain A mice with coincident leukemia: an electron microscopic study.
Topics: Adenoma; Animals; Histiocytes; Leukemia; Liver; Lung Neoplasms; Mice; Microscopy, Electron; Neoplasm | 1970 |
[The effect of urethane and N-hydroxyurethane on organ cultures of mouse lung tissue].
Topics: Animals; Embryo, Mammalian; Lung; Lung Neoplasms; Mice; Neoplasms, Experimental; Organ Culture Techn | 1970 |
Postnatal cellular proliferation in mouse and hamster lung.
Topics: Adenoma; Animals; Animals, Newborn; Autoradiography; Cell Division; Cell Nucleus; Cricetinae; DNA; L | 1970 |
[The effect of influenza virus on experimental carcinogenesis].
Topics: Animals; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experime | 1970 |
Absence of thymic involvement in the inhibition of urethan lung adenomagenesis by x-radiation.
Topics: Adenoma; Animals; Lung Neoplasms; Male; Mice; Radiation Effects; Thymectomy; Thymus Gland; Urethane | 1970 |
Recovery from the inhibitory effect of x-radiation on urethan lung adenomagenesis.
Topics: Adenoma; Animals; Female; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Radiation; Radiation | 1970 |
A study of nitrosamines and S-carboxyl derivatives of cysteine as lung carcinogens in adult SWR mice.
Topics: Animals; Cysteine; Female; Injections, Intraperitoneal; Liver Neoplasms; Lung Neoplasms; Male; Mice; | 1970 |
The induction of malignant melanomas in Syrian white hamster by neonatal exposure to urethan.
Topics: Age Factors; Animals; Animals, Newborn; Cricetinae; Female; Kidney Neoplasms; Liver Neoplasms; Lung | 1970 |
Susceptibility of guinea pigs to chemical carcinogens: 7,12-Dimethylbenz(a)anthracene and urethan.
Topics: Adenocarcinoma; Age Factors; Animals; Animals, Newborn; Benz(a)Anthracenes; Female; Guinea Pigs; Inj | 1970 |
[The relationship between the dose and the effect of a carcinogenic substance in experimental production of lung cancer].
Topics: Adenoma; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinoma; Lung Neoplasms; Mice; Neoplasms, Expe | 1970 |
Tumor incidence and cellularity in lungs of mice given various dose schedules of urethan.
Topics: Age Factors; Animals; Cell Count; Female; Hyperplasia; Lung; Lung Neoplasms; Mice; Neoplasms, Experi | 1970 |
[Tumors of the lung, reticulum and breast in BALB-c Cb-Se mice descending from parents treated with urethane in the neonatal period].
Topics: Animals; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Neo | 1970 |
[Age-specific sensitivity of mice embryos to the blastomogenic effect of urethane].
Topics: Adenoma; Animals; Female; Fetus; Gestational Age; Lung Neoplasms; Mice; Neoplasms, Experimental; Pre | 1971 |
Induction of lung adenomas by chronic inhalation of bis (chloromethyl) ether.
Topics: Adenoma; Aerosols; Alkylating Agents; Animals; Ethers; Lung Neoplasms; Male; Mice; Occupational Medi | 1971 |
Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.
Topics: Animals; Body Weight; Chlordan; Cycloheximide; Dactinomycin; Flavonoids; Hematocrit; Lung Neoplasms; | 1971 |
[On the effect of various pyrimidine derivatives on the blastogenic activity of urethane].
Topics: Animals; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Pyrimidines; Urethane | 1967 |
[On the effect of magnesium salts on the urethane induction of pulmonary adenomas in mice].
Topics: Adenoma; Animals; Lung Neoplasms; Magnesium; Male; Mice; Neoplasms, Experimental; Urethane | 1967 |
Tumours of the intestines induced in rats by intraperitoneal injections of N-methyl- and N-ethyl-N-nitrosourethanes.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Female; Injections, Intraperitoneal; Intestinal Neopl | 1968 |
Pulmonary adenoma of strain A mice: an electron microscopic study.
Topics: Adenoma; Aging; Animals; Lung Neoplasms; Mice; Microscopy, Electron; Urethane | 1968 |
Strain differences in carcinogenesis by urethane administration to suckling mice with special reference to induction of lung cancer.
Topics: Animals; Animals, Newborn; Carcinoma; Female; Hybridization, Genetic; Inbreeding; Injections, Subcut | 1968 |
Induction of malignant lymphoma and other tumors during experiments with anthralin painting of mice.
Topics: Acetone; Adenoma; Animals; Anthracenes; Carcinoma; Injections, Intraperitoneal; Lung Neoplasms; Lymp | 1968 |
Organ culture of lung tissue as a method for studying lung tumours and blastomogenic action of substances that can induce them.
Topics: Adenoma; Age Factors; Animals; Culture Techniques; Female; Lung; Lung Neoplasms; Mice; Neoplasms, Ex | 1968 |
[Early changes in the lungs of the progeny of mice following the effect of transplacental urethane].
Topics: Adenoma; Animals; Bronchial Neoplasms; Female; Hyperplasia; Lung; Lung Neoplasms; Maternal-Fetal Exc | 1968 |
[The transplacental blastomogenic effect of urethane at various stages in the postnatal life of mice].
Topics: Age Factors; Animals; Female; Fetus; Lung; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Neoplasms, | 1968 |
Carcinogenesis in dd-I mice injected during suckling period with urethane, nitrogen mustard N-oxide, and nitroso-urethane.
Topics: Adenoma; Animals; Animals, Newborn; Carcinoma; Female; Injections, Subcutaneous; Lacrimal Apparatus; | 1969 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Inje | 1969 |
[Alkaline phosphatase activity in lung tissues of XVII-G and C57BL mice].
Topics: Age Factors; Alkaline Phosphatase; Animals; Benz(a)Anthracenes; Bile Ducts; Female; Fluorenes; Histo | 1969 |
[The effect of thymine on the development of adenomain the lungs of mice under the influence of urethane and N-hydroxyurethane].
Topics: Adenoma; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Thymine; Urethane | 1969 |
Modification of urethan-lung tumor incidence by low x-radiation doses, cortisone, and transfusion of isotgenic lymphocytes.
Topics: Animals; beta-Aminoethyl Isothiourea; Cortisone; Injections, Intraperitoneal; Injections, Subcutaneo | 1969 |
Comparative study of lung carcinogenesis, promoting action in leukaemogenesis and initiating action in skin tumorigenesis by urethane, hydrazine and related compounds.
Topics: Animals; Carcinogens; Hydrazines; Leukemia, Experimental; Lung Neoplasms; Mice; Skin Neoplasms; Uret | 1969 |
An electron microscopic study of pulmonary adenomas in mice.
Topics: Adenoma; Animals; Carcinogens; Isoniazid; Lung Neoplasms; Mice; Microscopy, Electron; Neoplasms, Exp | 1965 |
[Influence of extract of Eleutherococcus on urethane-induced lung adenomas in mice].
Topics: Animals; Antineoplastic Agents; Lung Neoplasms; Mice; Neoplasms, Experimental; Plants, Medicinal; Ur | 1965 |
Lung tumours in mouse embryo homografts.
Topics: Animals; Embryo, Mammalian; Female; Hydrocarbons; Isoniazid; Leiomyoma; Lung; Lung Neoplasms; Mice; | 1965 |
Urethan carcinogenesis and nucleic acid metabolism: factors influencing lung adenoma induction.
Topics: Aminopterin; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Nucleic Acids; Orotic Acid; Thy | 1966 |
Carcinogenesis in naturally tumour-resistant mice. X-irradiation versus urethane as a carcinogenic agent.
Topics: Animals; Carcinogens; Female; In Vitro Techniques; Lung Neoplasms; Lymphoma; Male; Mammary Neoplasms | 1966 |
Incidence of lung tumours induced by urethane in mice exposed to reduced atmospheric pressure.
Topics: Animals; Atmospheric Pressure; Carcinogens; Female; Lung Neoplasms; Male; Mice; Neoplasms, Experimen | 1966 |
The carcinogenic action and metabolism of N-hydroxyurethane in newborn mice.
Topics: Animals; Carcinogens; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Urethane | 1966 |
Induction of lung tumours by the action of radiation and urethane.
Topics: Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Urethane | 1966 |