Page last updated: 2024-11-05

urethane and Hyperplasia

urethane has been researched along with Hyperplasia in 45 studies

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"Hyperplasia of pulmonary alveolar epithelium was induced by exposure of adult mice to 0-1% urethane in drinking water, and their lungs were analysed using combined autoradiographic and morphometric methods."7.65Autoradiographic study of type II-cell hyperplasia in lungs of mice chronicall exposed to urethane. ( Kauffman, SL, 1976)
" In conclusion, AKT1E17K induces hyperplasia of mouse lung epithelium in vivo and cooperates with urethane to induce the fully malignant phenotype."3.83AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer. ( Belmonte, S; Camastra, C; Colelli, F; De Marco, C; Fagman, H; Gagliardi, M; Malanga, D; Mignogna, C; Mirante, T; Oliveira, DM; Paciello, O; Papparella, S; Rizzuto, A; Scarfò, M; Viglietto, G, 2016)
"In the A/J strain of mice, urethane (ethyl carbamate) induces lung hyperplasia, adenoma, and adenocarcinoma in a time-dependent manner."3.69Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. ( Chen, A; Horio, Y; Malkinson, AM; Rice, P; Roth, JA; Schrump, DS, 1996)
"In rats with retinopathies induced by excess fluorescent light or injections of urethane, the retinal pigment epithelium (RPE) undergoes focal hyperplasia."3.67Intercellular junctions of hyperplastic retinal pigment epithelium. ( Hirsch, D; Korte, GE, 1986)
"Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer."1.38The influence of physical activity in the progression of experimental lung cancer in mice. ( Cal, RN; Cordeiro, JA; Cury, PM; dos Santos, CH; Nagamine, KK; Neiva, CM; Paceli, RB, 2012)
"Lung cancer is the leading cause of cancer-related death worldwide."1.38Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. ( Hayakawa, T; Imai, T; Imaida, K; Komiya, M; Mutoh, M; Takahashi, M; Tsuta, K; Ueno, T; Wakabayashi, K; Yanaka, A; Yoshimoto, M, 2012)
"We examined platelet deposition, microthrombus formation, and neointimal hyperplasia 4 weeks after stent placement by measuring the activity of 111In-labeled platelets, by using scanning electron microscopy, and by measuring neointimal thickness."1.29In vivo evaluation of a fluorine-acryl-stylene-urethane-silicone antithrombogenic coating material copolymer for intravascular stents. ( Ishibashi, T; Matsuhashi, T; Miyachi, H; Sakamoto, K; Yamadera, A, 1996)
"The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation."1.28Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991)
"The first group showed squamous cell carcinomas in the nasal cavity (4 out of 10 mice), trachea (4 out of 10 mice) and lung (2 out of 10 mice)."1.27Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice. ( Ide, G; Iwasaki, I; Takahashi, A, 1985)
"All types of ductal hyperplasias are characterized by intraductal epithelial hyperplasia and have been shown to give rise to mammal adenocarcinomas in situ or by transplantation into the mammary gland-free fat pads of syngeneic mice."1.26Preneoplastic lesions in murine mammary cancer. ( Medina, D, 1976)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199032 (71.11)18.7374
1990's5 (11.11)18.2507
2000's4 (8.89)29.6817
2010's3 (6.67)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Zhang, YQ1
Tu, BZ1
Sha, Q1
Wang, H1
Qian, J1
Malanga, D1
Belmonte, S1
Colelli, F1
Scarfò, M1
De Marco, C1
Oliveira, DM1
Mirante, T1
Camastra, C1
Gagliardi, M1
Rizzuto, A1
Mignogna, C1
Paciello, O1
Papparella, S1
Fagman, H1
Viglietto, G1
GREEN, JW2
LUSHBAUGH, CC2
STORER, JB1
Paceli, RB1
Cal, RN1
dos Santos, CH1
Cordeiro, JA1
Neiva, CM1
Nagamine, KK1
Cury, PM1
Ueno, T1
Imaida, K1
Yoshimoto, M1
Hayakawa, T1
Takahashi, M1
Imai, T1
Yanaka, A1
Tsuta, K1
Komiya, M1
Wakabayashi, K1
Mutoh, M1
BALL, JK1
FIELD, WE2
ROE, FJ2
WALTERS, M1
SKJAEGGESTAD, O1
Pulling, LC1
Vuillemenot, BR1
Hutt, JA1
Devereux, TR1
Belinsky, SA1
Ozaki, M1
Ozaki, K1
Watanabe, T1
Uwagawa, S1
Okuno, Y1
Shirai, T2
Masuda, A1
Hirose, M2
Ikawa, E1
Ito, N1
Imai, S1
Tsubura, Y1
Hilgers, J1
Iversen, OH1
Astrup, EG1
Böcking, A1
Mittermayer, C1
von Deimling, O1
Matsuhashi, T1
Miyachi, H1
Ishibashi, T1
Sakamoto, K1
Yamadera, A1
Horio, Y1
Chen, A1
Rice, P1
Roth, JA1
Malkinson, AM1
Schrump, DS1
Cazorla, M1
Hernández, L1
Fernández, PL1
Fabra, A1
Peinado, MA1
Dasenbrock, C1
Tillmann, T1
Kamino, K1
Campo, E1
Kohler, M1
Morawieltz, G1
Cardesa, A1
Tomatis, L1
Mohr, U1
Kolesnichenko, TS4
Antoshina, EE2
Mori, I1
Yasuhara, K2
Hayashi, SM1
Nonoyama, T1
Nomura, T1
Yanai, T1
Masegi, T1
Mitsumori, K2
Koujitani, T1
Tamura, T1
Onodera, H1
Takagi, H1
Takizawa, T1
Hayashi, Y1
Medina, D4
Gullino, PM2
Yuspa, SH1
Viguera, C1
Nims, R1
Brem, SS1
Smith, GP1
Abraham, JL1
Theiss, JC1
Shimkin, MB1
Warner, MR1
Kauffman, SL2
Hennings, H1
Jiang, TL1
Yan, SC1
Zhao, LF1
Witschi, HP2
Korte, GE1
Hirsch, D1
Takahashi, A1
Iwasaki, I1
Ide, G1
Morse, CC1
Sacquet, E1
Puvion, F1
Adenis, L1
Demaille, A1
Vesselinovitch, SD1
Mihailovich, N1
Matsuyama, M1
Suzuki, H1
Shabad, LM1
Smetanin, EY1
Slaga, TJ1
Bowden, GT1
Shapas, BG1
Boutwell, RK1
Kolechichenko, TS1
Kvitnitskaia, VA1
White, MR1
Grendon, A1
Jones, HB1

Reviews

1 review available for urethane and Hyperplasia

ArticleYear
The paradigm of two-stage carcinogenesis: a critical attitude.
    Cancer investigation, 1984, Volume: 2, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholan

1984

Other Studies

44 other studies available for urethane and Hyperplasia

ArticleYear
[Effectiveness of different epidural coverage materials for preventing postoperative scar hyperplasia and dural adhesion in spine].
    Zhonghua yi xue za zhi, 2022, Jul-19, Volume: 102, Issue:27

    Topics: Animals; Cattle; Cicatrix; Collagen; Gelatin; Hyperplasia; Laminectomy; Polyesters; Rats; Rats, Wist

2022
AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Bronchi; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Fe

2016
Mode of inhibition of cellular proliferation by urethane.
    The Proceedings of the Institute of Medicine of Chicago, 1948, Jun-15, Volume: 17, Issue:6

    Topics: Cell Proliferation; Humans; Hyperplasia; Urethane

1948
The influence of physical activity in the progression of experimental lung cancer in mice.
    Pathology, research and practice, 2012, Jul-15, Volume: 208, Issue:7

    Topics: Animals; Carcinogens; Disease Models, Animal; Disease Progression; Hyperplasia; Lung Neoplasms; Male

2012
Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice.
    Anticancer research, 2012, Volume: 32, Issue:11

    Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinogens; Humans; Hyperplasia; Immunohis

2012
THE CARCINOGENIC AND CO-CARCINOGENIC EFFECTS OF PARAFFIN WAX PELLETS AND GLASS BEADS IN THE MOUSE BLADDER.
    British journal of urology, 1964, Volume: 36

    Topics: Animals; Carcinogens; Epithelium; Foreign Bodies; Glass; Hyperplasia; Leukemia; Leukemia, Myeloid; L

1964
EXPERIMENTAL EPIDERMAL HYPERPLASIA IN MICE: RELATION TO CARCINOGENESIS.
    Acta pathologica et microbiologica Scandinavica. Supplementum, 1964

    Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Cantharidin; Carcinogenesis; Carcinogens; Cell Division;

1964
Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens.
    Cancer research, 2004, Jun-01, Volume: 64, Issue:11

    Topics: Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; C

2004
Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains.
    Toxicologic pathology, 2005, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Disease Models, Animal; Genes, p53; Genes, ras; Genet

2005
Histopathologic study of the mode of inhibition of cellular proliferation by urethane; effect of urethane on Walker rat carcinoma 256.
    Cancer research, 1949, Volume: 9, Issue:4

    Topics: Animals; Carcinoma 256, Walker; Cell Proliferation; Hyperplasia; Neoplasms; Rats; Urethane

1949
Enhancement of N-bis(2-hydroxypropyl)nitrosamine-initiated lung tumor development in rats by bleomycin and N-methyl-N-nitrosourethane.
    Cancer letters, 1984, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Animals; Bleomycin; Carcinogens; Drug Synergism; Hyperplasia; Lung; Lung Neoplasms;

1984
Urethan-induced mammary tumorigenesis in a murine mammary tumor virus (MuMTV)-positive mouse strain: evidence for a keratinized nodule as an MuMTV-negative precursor lesion for squamous cell tumors.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:4

    Topics: Animals; Carcinogens; Female; Hyperplasia; Immunoenzyme Techniques; Mammary Glands, Animal; Mammary

1984
Urethane-induced lung hyperplasia: carboxylesterase isozymes as markers in lung pathology.
    Laboratory investigation; a journal of technical methods and pathology, 1981, Volume: 44, Issue:2

    Topics: Animals; Carboxylic Ester Hydrolases; Female; Histocytochemistry; Hyperplasia; Lung; Mice; Microscop

1981
In vivo evaluation of a fluorine-acryl-stylene-urethane-silicone antithrombogenic coating material copolymer for intravascular stents.
    Academic radiology, 1996, Volume: 3, Issue:7

    Topics: Animals; Blood Platelets; Dogs; Equipment Design; Fluorine; Hyperplasia; Iliac Vein; Indium Radioiso

1996
Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Disease Progression; Exons; Genes, p53

1996
Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice.
    Molecular carcinogenesis, 1998, Volume: 21, Issue:4

    Topics: Adenoma; Animals; Carcinoma; Cell Transformation, Neoplastic; Codon; Disease Progression; DNA, Neopl

1998
[Epithelium hyperplasia in cultured organotypic aggregates obtained from cells of mouse embryonic lungs].
    Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:6

    Topics: Animals; Carcinogens; Cell Aggregation; Cells, Cultured; Epithelial Cells; Female; Histocytochemistr

1998
Aberrant expression of cyclin D1 in pulmonary proliferative lesions induced by high doses of urethane in transgenic mice carrying the human prototype c-H-ras gene.
    The Journal of veterinary medical science, 2001, Volume: 63, Issue:3

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Carcinogens; Female; Gene Expression Regulati

2001
Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
    The Journal of toxicological sciences, 2001, Volume: 26, Issue:3

    Topics: Adenoma; Animals; Bronchi; Carcinogenicity Tests; Carcinogens; Carcinoma; Cocarcinogenesis; Disease

2001
Preneoplastic lesions in murine mammary cancer.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Hyperplasia; Mammary Neop

1976
Considerations on the preneoplastic lesions of the mammary gland.
    The American journal of pathology, 1977, Volume: 89, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Bromocriptine; Cell Transformat

1977
Maintenance of human skin on nude mice for studies of chemical carcinogenesis.
    Cancer letters, 1979, Volume: 6, Issue:4-5

    Topics: Animals; Carcinogens; Female; Humans; Hyperplasia; Male; Mice; Mice, Nude; Models, Biological; Neopl

1979
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia.
    Science (New York, N.Y.), 1977, Mar-04, Volume: 195, Issue:4281

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Iri

1977
Scanning electron microscope surface morphometry of type II alveolar lung cell response to urethane in strain A mice.
    Scanning electron microscopy, 1979, Issue:3

    Topics: Animals; Female; Hyperplasia; Mice; Microscopy, Electron, Scanning; Microvilli; Pulmonary Alveoli; U

1979
Mammary tumorigenesis in chemical carcinogen-treated mice. IV. Induction of mammary ductal hyperplasias.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Female; Hyperplasia; Mammary

1976
Autoradiographic study of type II-cell hyperplasia in lungs of mice chronicall exposed to urethane.
    Cell and tissue kinetics, 1976, Volume: 9, Issue:5

    Topics: Animals; Cell Division; Cell Survival; Epithelial Cells; Epithelium; Female; Hyperplasia; Kinetics;

1976
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
    Basic life sciences, 1991, Volume: 57

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce

1991
Preventing effect of "liuwei dihuang decoction" on esophageal carcinoma.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2

    Topics: Animals; Cell Nucleus; Cyclic AMP; Cyclophosphamide; Drugs, Chinese Herbal; Epithelium; Esophageal N

1989
Separation of early diffuse alveolar cell proliferation from enhanced tumor development in mouse lung.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Animals; Butylated Hydroxytoluene; Cell Division; Hyperplasia; Lung Neoplasms; Male; Methylcholanthr

1986
Intercellular junctions of hyperplastic retinal pigment epithelium.
    Experientia, 1986, Jul-15, Volume: 42, Issue:7

    Topics: Animals; Cell Membrane Permeability; Histocytochemistry; Hyperplasia; Intercellular Junctions; Light

1986
Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:5

    Topics: Aerosols; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Epithelium; Hyperplasia; Lung Neoplas

1985
[Morphogenetic characteristics of the aggregates formed in epithelial and mesenchymal recombinations of the lungs from intact and urethane-exposed mouse embryos].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:1

    Topics: Animals; Culture Techniques; Epithelium; Female; Hyperplasia; Lung; Lung Neoplasms; Mesoderm; Metapl

1985
Cell kinetics in mouse lung following administration of carcinogens and butylated hydroxytoluene.
    Toxicology and applied pharmacology, 1985, Volume: 78, Issue:3

    Topics: Animals; Autoradiography; Butylated Hydroxytoluene; DNA; Drug Synergism; Hyperplasia; Injections, In

1985
[Mediastinal lymphoma of Swiss mice receiving urethane. X. Microscopic study of a series of germ-free animals receiving it for 10 weeks].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1970, Volume: 164, Issue:3

    Topics: Adenoma; Animals; Chemical and Drug Induced Liver Injury; Germ-Free Life; Hyperplasia; Leukocytosis;

1970
The effect of gonadectomy on the development of hepatomas induced by urethan.
    Cancer research, 1967, Volume: 27, Issue:10

    Topics: Adenoma; Adrenal Gland Diseases; Animals; Carcinoma, Hepatocellular; Castration; Female; Gonadal Ste

1967
Adrenal tumours and endocrine lesions induced in Syrian hamsters by urethane injected during suckling period.
    British journal of cancer, 1970, Volume: 24, Issue:2

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Animals; Animals, Newborn; Atrophy; Carcinogens; Crice

1970
Transplacental blastomogenesis in organ cultures of embryonic lung tissue.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:5

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Animals; Carcinogens; Female; Hyperplasia; Injections,

1971
Macromolecular synthesis following a single application of alkylating agents used as initiators of mouse skin tumorigenesis.
    Cancer research, 1973, Volume: 33, Issue:4

    Topics: Alkylating Agents; Animals; Croton Oil; Cytidine; DNA; Female; Hyperplasia; Leucine; Mice; Neoplasms

1973
Kinetics of alveolar epithelial hyperplasia in lungs of mice exposed to urethane. I. Quantitative analysis of cell populations.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 30, Issue:2

    Topics: Adenoma; Animals; Capillaries; Cell Count; Cell Division; Endothelium; Epithelial Cells; Female; Fib

1974
Mammary tumorigenesis in chemical carcinogen-treated mice. I. Incidence in BALB-c and C57BL mice.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:1

    Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Carcinogens; Hyperplasia; Mammary Neoplasms, Experiment

1974
[The short-term transplacental effect of urethane on organ cultures of embryonic mouse lung tissue].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:2

    Topics: Animals; Culture Techniques; Embryo, Mammalian; Female; Hyperplasia; Lung Diseases; Maternal-Fetal E

1970
Tumor incidence and cellularity in lungs of mice given various dose schedules of urethan.
    Cancer research, 1970, Volume: 30, Issue:4

    Topics: Age Factors; Animals; Cell Count; Female; Hyperplasia; Lung; Lung Neoplasms; Mice; Neoplasms, Experi

1970
[Early changes in the lungs of the progeny of mice following the effect of transplacental urethane].
    Voprosy onkologii, 1968, Volume: 14, Issue:6

    Topics: Adenoma; Animals; Bronchial Neoplasms; Female; Hyperplasia; Lung; Lung Neoplasms; Maternal-Fetal Exc

1968
Tumor promotion in the forestomach epithelium of mice by oral administration of citrus oils.
    Journal of the National Cancer Institute, 1965, Volume: 35, Issue:5

    Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Citrus; Glycols; Hyperplasia; Neoplasms, Exp

1965