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urethane and Hemangiosarcoma

urethane has been researched along with Hemangiosarcoma in 5 studies

Hemangiosarcoma: A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"To examine the tumor-promoting effect of troglitazone (TRG), a novel thiazolidinedione insulin-sensitizing agent, on splenic hemangiosarcomas in rasH2 mice, histopathological and molecular analyses were performed in the spleen of female rasH2 mice fed a diet containing 6,000 or 0 ppm TRG for 16 weeks after 1,000 or 0 mg/kg urethane (UR) initiation."7.74Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane. ( Dewa, Y; Hasumi, K; Jin, M; Matsumoto, S; Mitsumori, K; Nishimura, J; Saekusa, Y, 2008)
"We report subacute necrosis, peliosis hepatis, venoocclusive disease and hepatic angiosarcoma after long-term administration of urethane."4.78Liver disease from surreptitious administration of urethane. ( Cadranel, JF; Delamarre, N; Desaint, B; Florent, C; Legendre, C; Levy, VG, 1993)
"To examine the tumor-promoting effect of troglitazone (TRG), a novel thiazolidinedione insulin-sensitizing agent, on splenic hemangiosarcomas in rasH2 mice, histopathological and molecular analyses were performed in the spleen of female rasH2 mice fed a diet containing 6,000 or 0 ppm TRG for 16 weeks after 1,000 or 0 mg/kg urethane (UR) initiation."3.74Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane. ( Dewa, Y; Hasumi, K; Jin, M; Matsumoto, S; Mitsumori, K; Nishimura, J; Saekusa, Y, 2008)
"To determine if hemizygous transgenic mice carrying the human c-Ha-ras gene (CB6F1-Tg Hras2 mice (Hras2 mice)) are susceptible to the carcinogenic potential of known murine carcinogens, male and female Hras2 mice and their non-transgenic CB6F1 littermates (non-Tg mice) were each given a single intraperitoneal injection of 60 mg of vinyl carbamate (VC)/kg body weight or saline (vehicle control) and monitored for 16 wk without further treatment."3.69Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors. ( Hayashi, Y; Kodama, Y; Maronpot, RR; Mitsumori, K; Nomura, T; Wakana, S; Yamamoto, S; Yasuhara, K, 1997)
"Hepatic haemangiosarcoma is a deadly malignancy whose aetiology remains poorly understood."1.38ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model. ( Busch, SE; Gurley, KE; Kemp, CJ; Moser, RD, 2012)
" The tumors with a clear dose-response relationship were lung tumor (alveolar/bronchiolar adenoma or carcinoma) and liver tumor (hemangioma or angiosarcoma)."1.28Quantitative risk assessment of carcinogenicity of urethane (ethyl carbamate) on the basis of long-term oral administration to B6C3F1 mice. ( Arihiro, K; Inai, K; Khatun, N; Nishisaka, T; Tachiyama, Y; Takeshima, Y; Yonehara, S, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Busch, SE1
Gurley, KE1
Moser, RD1
Kemp, CJ1
Jin, M1
Matsumoto, S1
Dewa, Y1
Nishimura, J1
Saekusa, Y1
Hasumi, K1
Mitsumori, K2
Cadranel, JF1
Legendre, C1
Desaint, B1
Delamarre, N1
Florent, C1
Levy, VG1
Wakana, S1
Yamamoto, S1
Kodama, Y1
Yasuhara, K1
Nomura, T1
Hayashi, Y1
Maronpot, RR1
Inai, K1
Arihiro, K1
Takeshima, Y1
Yonehara, S1
Tachiyama, Y1
Khatun, N1
Nishisaka, T1

Reviews

1 review available for urethane and Hemangiosarcoma

ArticleYear
Liver disease from surreptitious administration of urethane.
    Journal of clinical gastroenterology, 1993, Volume: 17, Issue:1

    Topics: Chronic Disease; Female; Hemangiosarcoma; Humans; Liver; Liver Neoplasms; Middle Aged; Necrosis; Pel

1993

Other Studies

4 other studies available for urethane and Hemangiosarcoma

ArticleYear
ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model.
    The Journal of pathology, 2012, Volume: 227, Issue:3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Gene D

2012
Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane.
    Archives of toxicology, 2008, Volume: 82, Issue:10

    Topics: Angiogenic Proteins; Animals; Body Weight; Carcinogens; Cell Proliferation; Chromans; Female; Gene E

2008
Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:3

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Body Weight; Carcinogens; Codon; Disease Susceptibilit

1997
Quantitative risk assessment of carcinogenicity of urethane (ethyl carbamate) on the basis of long-term oral administration to B6C3F1 mice.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:4

    Topics: Adenoma; Animals; Carcinogens, Environmental; Carcinoma; Chi-Square Distribution; Dose-Response Rela

1991